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Search of human proteins with 20070107
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
(354 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 730 0.0
gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens] 334 8e-92
gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens] 327 1e-89
gi|4557489 cone-rod homeobox protein [Homo sapiens] 224 1e-58
gi|12707580 paired-like homeobox 2b [Homo sapiens] 116 3e-26
gi|4826912 paired-like homeodomain 3 [Homo sapiens] 103 3e-22
gi|46249382 paired-like homeobox 2a [Homo sapiens] 103 3e-22
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 103 3e-22
gi|24497589 aristaless related homeobox [Homo sapiens] 102 4e-22
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 102 5e-22
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 102 7e-22
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 101 1e-21
gi|14149760 orthopedia homeobox [Homo sapiens] 101 1e-21
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 96 6e-20
gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 93 3e-19
gi|7706659 paired related homeobox 2 [Homo sapiens] 92 9e-19
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap... 89 6e-18
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 88 1e-17
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 88 1e-17
gi|122937321 UNC homeobox [Homo sapiens] 88 1e-17
gi|21361183 paired-like homeodomain transcription factor 2 isofo... 87 2e-17
gi|24234711 paired-like homeodomain transcription factor 2 isofo... 87 2e-17
gi|24234708 paired-like homeodomain transcription factor 2 isofo... 87 2e-17
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 87 2e-17
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 87 2e-17
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 87 2e-17
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 87 3e-17
gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens] 86 4e-17
gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] 86 4e-17
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens] 86 4e-17
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 730 bits (1885), Expect = 0.0
Identities = 354/354 (100%), Positives = 354/354 (100%)
Query: 1 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT 60
MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT
Sbjct: 1 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT 60
Query: 61 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSG 120
RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSG
Sbjct: 61 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSG 120
Query: 121 SESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPA 180
SESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPA
Sbjct: 121 SESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPA 180
Query: 181 SISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSS 240
SISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSS
Sbjct: 181 SISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSS 240
Query: 241 SYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHH 300
SYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHH
Sbjct: 241 SYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHH 300
Query: 301 HQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL 354
HQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL
Sbjct: 301 HQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL 354
>gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]
Length = 289
Score = 334 bits (856), Expect = 8e-92
Identities = 209/363 (57%), Positives = 232/363 (63%), Gaps = 83/363 (22%)
Query: 1 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT 60
MMSYLKQPPY +NGL L MDLLHPSVGYPATPRKQRRERTTFTR+QLDVLEALFAKT
Sbjct: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKT 60
Query: 61 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ---SGSGTKSRPAKKKSSPVRE 117
RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ +G K RPAKKK+SP RE
Sbjct: 61 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPARE 120
Query: 118 -SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSI 176
SS S +SGQFTPP SS S + ASSS+ PV SI
Sbjct: 121 VSSESGTSGQFTPP---SSTSVPTIASSSA--------------PV------------SI 151
Query: 177 WSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYP 236
WSPASISP S P S S +SCMQRS YPM+Y Q Y QGY
Sbjct: 152 WSPASISPLSDPLSTS----------SSCMQRS-----------YPMTYTQASGYSQGY- 189
Query: 237 TPSSSYFGGVDCSSYLAPMHSHHHP---HQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHH 293
S+SYFGG+DC SYL PMH H P LSPM +++ H + P + LS
Sbjct: 190 AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPAS---LST----- 240
Query: 294 HHHHHHHHQGYGGSGLAFNS-ADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQ-ASWRF 351
QGYG S L FNS DCLDYK+ +++WKLNFN+ DCLDYKDQ +SW+F
Sbjct: 241 --------QGYGASSLGFNSTTDCLDYKD-----QTASWKLNFNA-DCLDYKDQTSSWKF 286
Query: 352 QVL 354
QVL
Sbjct: 287 QVL 289
>gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens]
Length = 297
Score = 327 bits (837), Expect = 1e-89
Identities = 209/371 (56%), Positives = 232/371 (62%), Gaps = 91/371 (24%)
Query: 1 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYP--------ATPRKQRRERTTFTRSQLDV 52
MMSYLKQPPY +NGL L MDLLHPSVGYP ATPRKQRRERTTFTR+QLDV
Sbjct: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60
Query: 53 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ---SGSGTKSRPAK 109
LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ +G K RPAK
Sbjct: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120
Query: 110 KKSSPVRE-SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSL 168
KK+SP RE SS S +SGQFTPP SS S + ASSS+ PV
Sbjct: 121 KKTSPAREVSSESGTSGQFTPP---SSTSVPTIASSSA--------------PV------ 157
Query: 169 STPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQG 228
SIWSPASISP S P S S +SCMQRS YPM+Y Q
Sbjct: 158 ------SIWSPASISPLSDPLSTS----------SSCMQRS-----------YPMTYTQA 190
Query: 229 GSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHP---HQLSPMAPSSMAGHHHHHPHAHHP 285
Y QGY S+SYFGG+DC SYL PMH H P LSPM +++ H + P +
Sbjct: 191 SGYSQGY-AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPAS--- 245
Query: 286 LSQSSGHHHHHHHHHHQGYGGSGLAFNS-ADCLDYKEPGAAAASSAWKLNFNSPDCLDYK 344
LS QGYG S L FNS DCLDYK+ +++WKLNFN+ DCLDYK
Sbjct: 246 LST-------------QGYGASSLGFNSTTDCLDYKD-----QTASWKLNFNA-DCLDYK 286
Query: 345 DQ-ASWRFQVL 354
DQ +SW+FQVL
Sbjct: 287 DQTSSWKFQVL 297
>gi|4557489 cone-rod homeobox protein [Homo sapiens]
Length = 299
Score = 224 bits (570), Expect = 1e-58
Identities = 152/366 (41%), Positives = 198/366 (54%), Gaps = 79/366 (21%)
Query: 1 MMSYLKQPP-YGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAK 59
MM+Y+ P Y +N L L+GP++DL+H +V YP+ PRKQRRERTTFTRSQL+ LEALFAK
Sbjct: 1 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK 60
Query: 60 TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQS--------GSGTKSRPAKKK 111
T+YPD++ REEVALKINLPESRVQVWFKNRRAKCRQQ+Q G K+RPAK+K
Sbjct: 61 TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK 120
Query: 112 SSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTP 171
+ T P S+ S S +P G G+P A +++
Sbjct: 121 AG--------------TSPRPSTDVCPDPLGISDSYSP---PLPGPSGSPTTAVATV--- 160
Query: 172 AASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSY 231
SIWSPAS SP +PE A VA+G + +A Y M+Y ++
Sbjct: 161 ---SIWSPASESP--------LPEAQRA--------GLVASGPSLTSAPYAMTYAPASAF 201
Query: 232 ---GQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQ 288
Y +P SSYF G+D YL+PM QL A S ++G A P S
Sbjct: 202 CSSPSAYGSP-SSYFSGLD--PYLSPM-----VPQLGGPALSPLSGPSVGPSLAQSPTSL 253
Query: 289 SSGHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQAS 348
S Q YG A++ D L++K+P + WK +N D LDYKDQ++
Sbjct: 254 SG-----------QSYG----AYSPVDSLEFKDP-----TGTWKFTYNPMDPLDYKDQSA 293
Query: 349 WRFQVL 354
W+FQ+L
Sbjct: 294 WKFQIL 299
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 116 bits (290), Expect = 3e-26
Identities = 84/217 (38%), Positives = 112/217 (51%), Gaps = 32/217 (14%)
Query: 36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT +QL LE +FA+T YPDI+ REE+ALKI+L E+RVQVWF+NRRAK R+
Sbjct: 96 RKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 155
Query: 96 QQQS-----------GSGTKSRPAKKKSSPVRESSGSESSGQFTP---PAVSSSASSSSS 141
Q+++ SG KS ++ S +S+ +S+G P P S A+
Sbjct: 156 QERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPTPSCGANGGGG 215
Query: 142 ASSSSAN-PAAAAAAGLGGNP------------VAAASSLSTPAASSIWSPASISPGSAP 188
S A P AA G GG P AAA++ + AA + + G AP
Sbjct: 216 GGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGGPGQGWAP 275
Query: 189 AS---VSVPEPLAAP--SNTSCMQRSVAAGAATAAAS 220
S+P+ L P S S +QR A AA +S
Sbjct: 276 GPGPITSIPDSLGGPFASVLSSLQRPNGAKAALVKSS 312
>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
Length = 302
Score = 103 bits (256), Expect = 3e-22
Identities = 74/202 (36%), Positives = 103/202 (50%), Gaps = 26/202 (12%)
Query: 36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
+KQRR+RT FT QL LEA F + RYPD+ REE+A+ NL E+RV+VWFKNRRAK R+
Sbjct: 60 KKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRK 119
Query: 96 QQQSG-----SGTKSRPAKKKSSPVRESSGSESSGQFTPPAVS------------SSASS 138
+++S G+ + P P E S G + P A++ +S +
Sbjct: 120 RERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNV 179
Query: 139 SSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLA 198
AS +P ++ AA + P AAA+ + P ++ PG APA+VS
Sbjct: 180 GPLASQPVFSPPSSIAASM--VPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVS------ 231
Query: 199 APSNTSCMQRSVAAGAATAAAS 220
SC S AA AA AA+S
Sbjct: 232 -SGAVSCPYASAAAAAAAAASS 252
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 103 bits (256), Expect = 3e-22
Identities = 69/180 (38%), Positives = 86/180 (47%), Gaps = 35/180 (19%)
Query: 36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT +QL LE +FA+T YPDI+ REE+ALKI+L E+RVQVWF+NRRAK R+
Sbjct: 88 RKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 147
Query: 96 QQQSGS--GTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPA--- 150
Q+++ S G KK S +S P S+AS + A+P
Sbjct: 148 QERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSP 207
Query: 151 -------------------------AAAAAGLGGNPVAAASSLSTPAASSIWSPASISPG 185
A A G GG P A A+ L W PA PG
Sbjct: 208 SPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAGAAEL-----LKAWQPAESGPG 262
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 103 bits (256), Expect = 3e-22
Identities = 63/166 (37%), Positives = 87/166 (52%), Gaps = 12/166 (7%)
Query: 36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT QL+ LEA+FA+T YPD+F REE+A+KINL E+RVQVWF+NRRAK R+
Sbjct: 36 RKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRK 95
Query: 96 QQQSGS----GTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPAA 151
++ S G K A+ PVR + +PP + S + + +
Sbjct: 96 TERGASDQEPGAKEPMAEVTPPPVRNIN--------SPPPGDQARSKKEALEAQQSLGRT 147
Query: 152 AAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPL 197
AG + L+T + S + G S VP+P+
Sbjct: 148 VGPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPM 193
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 102 bits (255), Expect = 4e-22
Identities = 78/202 (38%), Positives = 114/202 (56%), Gaps = 20/202 (9%)
Query: 36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT QL+ LE F KT YPD+F REE+A++++L E+RVQVWF+NRRAK R+
Sbjct: 326 RKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRK 385
Query: 96 QQQSGSGT--KSRPAKKKSSPVRESSGSESSGQFTP--PAVSSSASSSSSASSSSANPAA 151
++++G+ T P S S + F P PA+ SA ++++A++++A P+
Sbjct: 386 REKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPAL-DSAWTAAAAAAAAAFPSL 444
Query: 152 AAAAGLGGNPVAAAS-SLSTPAASSIW-SPASISPGSAPASVSVPEPLAAPSNTSCMQR- 208
G P + A LST ++++ PA ISP S PL + S + + R
Sbjct: 445 PPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFG-RLFSTMAPLTSASTAAALLRQ 503
Query: 209 -------SVAAGA----ATAAA 219
+VA+GA ATAAA
Sbjct: 504 PTPAVEGAVASGALADPATAAA 525
Score = 34.7 bits (78), Expect = 0.13
Identities = 35/137 (25%), Positives = 56/137 (40%), Gaps = 19/137 (13%)
Query: 89 RRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSAN 148
RR+ C+ + + + P ++ P + GS S SS+ +
Sbjct: 35 RRSPCKMRLLGAAQSLPAPLTSRADPEKAVQGSPKS------------SSAPFEAELHLP 82
Query: 149 PAAAAAAGLGGNPV---AAASSLSTPAASSIWSPASISP-GSAPASVSVPEPLAAPSNTS 204
P G GG + AAA++ + AA++ + A+ P G AP P P A P
Sbjct: 83 PKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATAGPRGEAPPP---PPPTARPGERP 139
Query: 205 CMQRSVAAGAATAAASY 221
+ AA AA AAA++
Sbjct: 140 DGAGAAAAAAAAAAAAW 156
Score = 29.6 bits (65), Expect = 4.3
Identities = 38/146 (26%), Positives = 54/146 (36%), Gaps = 24/146 (16%)
Query: 97 QQSGSGTKSRPAKKKSSPVRESSGSESS--GQFTPPAVS--SSASSSSSASSSSANPAAA 152
Q G RP K SP SS S G+ +P + +A S + +S A+P A
Sbjct: 4 QYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADPEKA 63
Query: 153 AAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAA 212
G+P S S P + + P + L P +Q + AA
Sbjct: 64 VQ----GSP----KSSSAPFEAELHLPPKL------------RRLYGPGGGRLLQGAAAA 103
Query: 213 GAATAAASYPMSYGQGGSYGQGYPTP 238
AA AAA+ + G G+ P P
Sbjct: 104 AAAAAAAAAAAATATAGPRGEAPPPP 129
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 102 bits (254), Expect = 5e-22
Identities = 97/313 (30%), Positives = 127/313 (40%), Gaps = 71/313 (22%)
Query: 17 LAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKIN 76
LAG + Y + RKQRR RT FT QL+ LE F KT YPD+ MRE +A+ N
Sbjct: 50 LAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTN 109
Query: 77 LPESRVQVWFKNRRAKCRQQQQS----------------GSG------------TKSRPA 108
LPE+RVQVWFKNRRAK R++Q+S G G T+ P
Sbjct: 110 LPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPR 169
Query: 109 KKKSSP-------VRESSGSES-------------SGQFTPPAVSSSASSSSSASSSSAN 148
S P + E S SES +G P A S + S +
Sbjct: 170 LPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGS 229
Query: 149 PAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSN----TS 204
P A + L PVA L P+ S SP S+ + +AA +N +S
Sbjct: 230 PKADSPGSLTITPVAPGGGLLGPSHSYSSSPLSL----FRLQEQFRQHMAATNNLVHYSS 285
Query: 205 CMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQ- 263
A AA AAA+ P Y + + G + C SY + + HQ
Sbjct: 286 FEVGGPAPAAAAAAAAVP------------YLGVNMAPLGSLHCQSYYQSLSAAAAAHQG 333
Query: 264 --LSPMAPSSMAG 274
SP+ P+ AG
Sbjct: 334 VWGSPLLPAPPAG 346
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 102 bits (253), Expect = 7e-22
Identities = 94/299 (31%), Positives = 123/299 (41%), Gaps = 71/299 (23%)
Query: 31 YPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRR 90
Y + RKQRR RT FT QL+ LE F KT YPD+ MRE +A+ NLPE+RVQVWFKNRR
Sbjct: 59 YGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRR 118
Query: 91 AKCRQQQQS----------------GSG------------TKSRPAKKKSSP-------V 115
AK R++Q+S G G T+ P S P +
Sbjct: 119 AKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSL 178
Query: 116 RESSGSES-------------SGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPV 162
E S SES +G P A S + S +P A + L PV
Sbjct: 179 SEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPV 238
Query: 163 AAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSN----TSCMQRSVAAGAATAA 218
A L P+ S SP S+ + +AA +N +S A AA AA
Sbjct: 239 APGGGLLGPSHSYSSSPLSL----FRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAA 294
Query: 219 ASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQ---LSPMAPSSMAG 274
A+ P Y + + G + C SY + + HQ SP+ P+ AG
Sbjct: 295 AAVP------------YLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAG 341
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 101 bits (251), Expect = 1e-21
Identities = 72/179 (40%), Positives = 99/179 (55%), Gaps = 22/179 (12%)
Query: 36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
+KQ+R RT FT +QL+ LE FAKT YPDIFMREE+AL+I L ESRVQVWF+NRRAK ++
Sbjct: 102 QKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKK 161
Query: 96 QQQSGSGTKSRPAKKKSSPVRESSG----SESSGQFTPPAVSSSASSSSSASSSSANP-- 149
+KK++ V + G + QF A +++A+ S S AN
Sbjct: 162 -------------RKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTR 208
Query: 150 -AAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQ 207
AAAA G+ P+ A A S+ S S++ G P S+ + LA SN + +Q
Sbjct: 209 WAAAAMPGVSQLPLPPALGRQQAMAQSL-SQCSLAAGPPPNSMGLSNSLAG-SNGAGLQ 265
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 101 bits (251), Expect = 1e-21
Identities = 72/179 (40%), Positives = 99/179 (55%), Gaps = 22/179 (12%)
Query: 36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
+KQ+R RT FT +QL+ LE FAKT YPDIFMREE+AL+I L ESRVQVWF+NRRAK ++
Sbjct: 102 QKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKK 161
Query: 96 QQQSGSGTKSRPAKKKSSPVRESSG----SESSGQFTPPAVSSSASSSSSASSSSANP-- 149
+KK++ V + G + QF A +++A+ S S AN
Sbjct: 162 -------------RKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTR 208
Query: 150 -AAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQ 207
AAAA G+ P+ A A S+ S S++ G P S+ + LA SN + +Q
Sbjct: 209 WAAAAMPGVSQLPLPPALGRQQAMAQSL-SQCSLAAGPPPNSMGLSNSLAG-SNGAGLQ 265
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 95.5 bits (236), Expect = 6e-20
Identities = 75/229 (32%), Positives = 94/229 (41%), Gaps = 44/229 (19%)
Query: 27 PSVGYPATP--------------RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVA 72
PS G P P +K RR RTTFT QL LE F K+ YPD++ REE+A
Sbjct: 111 PSPGLPVGPATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELA 170
Query: 73 LKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAV 132
K+NLPE RVQVWF+NRRAK R+Q++ + K + SP+ S S S +P
Sbjct: 171 GKVNLPEVRVQVWFQNRRAKWRRQEK----LEVSSMKLQDSPLLSFSRSPPSATLSP--- 223
Query: 133 SSSASSSSSASSSSANPAAAAAAGLGGNPVAAA----SSLSTPAASSIWSPASISPGSAP 188
A G GG P A S L P + PG P
Sbjct: 224 ------------------LGAGPGSGGGPAGGALPLESWLGPPLPGGGATALQSLPGFGP 265
Query: 189 ASVSVPEPLAAPSNTSCMQRSVAAG-AATAAASYPMSYGQGGSYGQGYP 236
+ S+P P S G A P SY G +G +P
Sbjct: 266 PAQSLPASYTPPPPPPPFLNSPPLGPGLQPLAPPPPSYPCGPGFGDKFP 314
>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
sapiens]
Length = 314
Score = 93.2 bits (230), Expect = 3e-19
Identities = 62/183 (33%), Positives = 93/183 (50%), Gaps = 28/183 (15%)
Query: 32 PATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRA 91
PA +KQRR+RT FT QL LEA F + RYPD+ MREE+A+ NL E RV+VWFKNRRA
Sbjct: 83 PAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRA 142
Query: 92 KCRQQQQ--------------------------SGSGTKSRPAKKKSSPVRESSGSESSG 125
K R++++ + + + A K +P S+ S +
Sbjct: 143 KWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFF 202
Query: 126 QFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPG 185
P S S S+ S+ SS P++ + G P + ++++ SS+ S ++SPG
Sbjct: 203 NSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGSSLNS--AMSPG 260
Query: 186 SAP 188
+ P
Sbjct: 261 ACP 263
>gi|7706659 paired related homeobox 2 [Homo sapiens]
Length = 253
Score = 91.7 bits (226), Expect = 9e-19
Identities = 60/167 (35%), Positives = 93/167 (55%), Gaps = 5/167 (2%)
Query: 6 KQPPYGMNGLGLAGPAMDLLHPSVGYPAT-PRKQRRERTTFTRSQLDVLEALFAKTRYPD 64
++P G +G A + P G A +KQRR RTTF SQL LE +F +T YPD
Sbjct: 71 REPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPD 130
Query: 65 IFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESS 124
F+REE+A ++NL E+RVQVWF+NRRAK R+ +++ ++S K S + + E
Sbjct: 131 AFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYS---QEAAIEQP 187
Query: 125 GQFTPPAVSSS-ASSSSSASSSSANPAAAAAAGLGGNPVAAASSLST 170
P A+S S ++S+ S+ P + ++G V A+S+++
Sbjct: 188 VAPRPTALSPDYLSWTASSPYSTVPPYSPGSSGPATPGVNMANSIAS 234
>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
sapiens]
Length = 184
Score = 89.0 bits (219), Expect = 6e-18
Identities = 47/91 (51%), Positives = 60/91 (65%), Gaps = 2/91 (2%)
Query: 19 GPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLP 78
GPA + G A +K RR RTTFT QL LE F + YPD++ REE+A K++LP
Sbjct: 8 GPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLP 67
Query: 79 ESRVQVWFKNRRAKCRQQQ--QSGSGTKSRP 107
E RVQVWF+NRRAK R+Q+ +SGSG + P
Sbjct: 68 EVRVQVWFQNRRAKWRRQERLESGSGAVAAP 98
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 87.8 bits (216), Expect = 1e-17
Identities = 65/192 (33%), Positives = 95/192 (49%), Gaps = 29/192 (15%)
Query: 16 GLAGPAMDLLHP--SVGYPATPR------KQRRERTTFTRSQLDVLEALFAKTRYPDIFM 67
G GP + LH S G P + K+RR RTTF+ QL+ LE +F KT YPD++
Sbjct: 123 GSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYA 182
Query: 68 REEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQF 127
RE++AL+ +L E+RVQVWF+NRRAK R++++ G + R + + ++S Q
Sbjct: 183 REQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDSHPQL 242
Query: 128 TPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSA 187
+S AS S +P GG + + + +P SP S GS
Sbjct: 243 ---------QNSLWASPGSGSP--------GGPCLVSPEGIPSPC----MSPYSHPHGSV 281
Query: 188 PASVSVPEPLAA 199
+ VP P AA
Sbjct: 282 AGFMGVPAPSAA 293
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 87.8 bits (216), Expect = 1e-17
Identities = 58/164 (35%), Positives = 90/164 (54%), Gaps = 15/164 (9%)
Query: 37 KQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ 96
K+RR RTTFT QL+ LE +F KT YPD++ RE++A++ +L E+RVQVWF+NRRAK R++
Sbjct: 213 KKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKR 272
Query: 97 QQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPA--VSSSASSSSSASSSSANPAAAAA 154
++ G + R + + + +E+ Q P+ ++ A+S A +P A
Sbjct: 273 ERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVPCDPVPACM 332
Query: 155 AGLGGNPVAAASS----LSTPAA---------SSIWSPASISPG 185
+ P + ASS LS A S++ AS+SPG
Sbjct: 333 SPHAHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPG 376
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 87.8 bits (216), Expect = 1e-17
Identities = 69/217 (31%), Positives = 97/217 (44%), Gaps = 37/217 (17%)
Query: 37 KQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ 96
K+RR RT FT QL+ LE F ++ YPD+FMRE +AL+++L ESRVQVWF+NRRAK R++
Sbjct: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
Query: 97 QQSGSGTKSRPA---------------------------KKKSSPVRESSGSESSGQFTP 129
+ + G RPA KKK ++ S+ +P
Sbjct: 164 ENTKKG-PGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSP 222
Query: 130 PAVSSSASSSSSASSSSA-------NPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASI 182
+S ++ SS + S P AA G G + AA + P +P +
Sbjct: 223 GGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPP-APGTC 281
Query: 183 SPGSAPASVSVPEPLAAPSNTSCMQ-RSVAAGAATAA 218
P P+ S P P + S GAA AA
Sbjct: 282 DPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAA 318
Score = 36.6 bits (83), Expect = 0.035
Identities = 33/105 (31%), Positives = 44/105 (41%), Gaps = 12/105 (11%)
Query: 107 PAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPA---------AAAAAGL 157
PA + P + S G+ S P + + S + AS + PA AAA G
Sbjct: 413 PAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGG 472
Query: 158 GGNPVAAASSLSTP---AASSIWSPASISPGSAPASVSVPEPLAA 199
GG+ A ++ P A S P SP PA+ VPEP AA
Sbjct: 473 GGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAA 517
Score = 30.8 bits (68), Expect = 1.9
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 10/75 (13%)
Query: 97 QQSGSGTKSRPAKKKSSPVRESS----------GSESSGQFTPPAVSSSASSSSSASSSS 146
Q+SG+G + RP + G+ + +P +V S S S ++
Sbjct: 289 QRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAA 348
Query: 147 ANPAAAAAAGLGGNP 161
+N AAAAAAGL P
Sbjct: 349 SNAAAAAAAGLDFAP 363
>gi|21361183 paired-like homeodomain transcription factor 2 isoform
c [Homo sapiens]
Length = 324
Score = 87.4 bits (215), Expect = 2e-17
Identities = 60/189 (31%), Positives = 105/189 (55%), Gaps = 24/189 (12%)
Query: 32 PATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRA 91
P+ ++QRR+RT FT QL LEA F + RYPD+ REE+A+ NL E+RV+VWFKNRRA
Sbjct: 86 PSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRA 145
Query: 92 KCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTP-----PAVS-SSASSSSSASSS 145
K R+++++ +++ + G + +G P P S ++ ++ S+S
Sbjct: 146 KWRKRERN----------QQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS 195
Query: 146 SANPAAAAAAGLGGNPVAAAS------SLSTPAASSIWSPASIS--PGSAPASVSVPEPL 197
+ + + NP+++ S S+S+ + SS P++++ PGS+ S++ L
Sbjct: 196 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL 255
Query: 198 AAPSNTSCM 206
++PS S +
Sbjct: 256 SSPSLNSAV 264
>gi|24234711 paired-like homeodomain transcription factor 2 isoform
a [Homo sapiens]
Length = 271
Score = 87.4 bits (215), Expect = 2e-17
Identities = 60/189 (31%), Positives = 105/189 (55%), Gaps = 24/189 (12%)
Query: 32 PATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRA 91
P+ ++QRR+RT FT QL LEA F + RYPD+ REE+A+ NL E+RV+VWFKNRRA
Sbjct: 33 PSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRA 92
Query: 92 KCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTP-----PAVS-SSASSSSSASSS 145
K R+++++ +++ + G + +G P P S ++ ++ S+S
Sbjct: 93 KWRKRERN----------QQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS 142
Query: 146 SANPAAAAAAGLGGNPVAAAS------SLSTPAASSIWSPASIS--PGSAPASVSVPEPL 197
+ + + NP+++ S S+S+ + SS P++++ PGS+ S++ L
Sbjct: 143 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL 202
Query: 198 AAPSNTSCM 206
++PS S +
Sbjct: 203 SSPSLNSAV 211
>gi|24234708 paired-like homeodomain transcription factor 2 isoform
b [Homo sapiens]
Length = 317
Score = 87.4 bits (215), Expect = 2e-17
Identities = 60/189 (31%), Positives = 105/189 (55%), Gaps = 24/189 (12%)
Query: 32 PATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRA 91
P+ ++QRR+RT FT QL LEA F + RYPD+ REE+A+ NL E+RV+VWFKNRRA
Sbjct: 79 PSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRA 138
Query: 92 KCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTP-----PAVS-SSASSSSSASSS 145
K R+++++ +++ + G + +G P P S ++ ++ S+S
Sbjct: 139 KWRKRERN----------QQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS 188
Query: 146 SANPAAAAAAGLGGNPVAAAS------SLSTPAASSIWSPASIS--PGSAPASVSVPEPL 197
+ + + NP+++ S S+S+ + SS P++++ PGS+ S++ L
Sbjct: 189 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL 248
Query: 198 AAPSNTSCM 206
++PS S +
Sbjct: 249 SSPSLNSAV 257
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 87.4 bits (215), Expect = 2e-17
Identities = 84/277 (30%), Positives = 114/277 (41%), Gaps = 60/277 (21%)
Query: 6 KQPPYGMNG-LGLAGPAMDLLHPSVGYPATP--RKQRRERTTFTRSQLDVLEALFAKTRY 62
K+ + ++G LG G +D P P RKQRR RTTFT QL+ LE F +T Y
Sbjct: 182 KKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHY 241
Query: 63 PDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-------------------------- 96
PDI+ REE+A + L E+RVQVWF NRRA+ R+Q
Sbjct: 242 PDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLP 301
Query: 97 --------------QQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSA 142
Q G T RP S + + + ++ + + S SS
Sbjct: 302 PYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSY 361
Query: 143 SSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPL----- 197
S S NPAA + N + S+ +P SI S P A S+ PL
Sbjct: 362 SDSFMNPAAPS------NHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSI-SPLHGGLD 414
Query: 198 -AAPSNTSCMQR--SVAAGAA--TAAASYPMSYGQGG 229
A + SC QR S+ G + T+ A P +Y G
Sbjct: 415 SATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTG 451
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 87.4 bits (215), Expect = 2e-17
Identities = 84/277 (30%), Positives = 114/277 (41%), Gaps = 60/277 (21%)
Query: 6 KQPPYGMNG-LGLAGPAMDLLHPSVGYPATP--RKQRRERTTFTRSQLDVLEALFAKTRY 62
K+ + ++G LG G +D P P RKQRR RTTFT QL+ LE F +T Y
Sbjct: 180 KKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHY 239
Query: 63 PDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-------------------------- 96
PDI+ REE+A + L E+RVQVWF NRRA+ R+Q
Sbjct: 240 PDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLP 299
Query: 97 --------------QQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSA 142
Q G T RP S + + + ++ + + S SS
Sbjct: 300 PYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSY 359
Query: 143 SSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPL----- 197
S S NPAA + N + S+ +P SI S P A S+ PL
Sbjct: 360 SDSFMNPAAPS------NHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSI-SPLHGGLD 412
Query: 198 -AAPSNTSCMQR--SVAAGAA--TAAASYPMSYGQGG 229
A + SC QR S+ G + T+ A P +Y G
Sbjct: 413 SATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTG 449
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 87.4 bits (215), Expect = 2e-17
Identities = 84/277 (30%), Positives = 114/277 (41%), Gaps = 60/277 (21%)
Query: 6 KQPPYGMNG-LGLAGPAMDLLHPSVGYPATP--RKQRRERTTFTRSQLDVLEALFAKTRY 62
K+ + ++G LG G +D P P RKQRR RTTFT QL+ LE F +T Y
Sbjct: 182 KKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHY 241
Query: 63 PDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-------------------------- 96
PDI+ REE+A + L E+RVQVWF NRRA+ R+Q
Sbjct: 242 PDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLP 301
Query: 97 --------------QQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSA 142
Q G T RP S + + + ++ + + S SS
Sbjct: 302 PYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSY 361
Query: 143 SSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPL----- 197
S S NPAA + N + S+ +P SI S P A S+ PL
Sbjct: 362 SDSFMNPAAPS------NHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSI-SPLHGGLD 414
Query: 198 -AAPSNTSCMQR--SVAAGAA--TAAASYPMSYGQGG 229
A + SC QR S+ G + T+ A P +Y G
Sbjct: 415 SATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTG 451
>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
Length = 245
Score = 86.7 bits (213), Expect = 3e-17
Identities = 49/119 (41%), Positives = 73/119 (61%), Gaps = 7/119 (5%)
Query: 36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTF SQL LE +F +T YPD F+RE++A ++NL E+RVQVWF+NRRAK R+
Sbjct: 92 RKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRR 151
Query: 96 QQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAA 154
+ ++ A K +S ++ SG ++ + P + + S +A+P +A A
Sbjct: 152 NE------RAMLANKNASLLKSYSGDVTAVE-QPIVPRPAPRPTDYLSWGTASPYSAMA 203
>gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens]
Length = 225
Score = 86.3 bits (212), Expect = 4e-17
Identities = 40/64 (62%), Positives = 50/64 (78%)
Query: 34 TPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 93
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 113 TKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 172
Query: 94 RQQQ 97
R+Q+
Sbjct: 173 RKQE 176
>gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens]
Length = 292
Score = 86.3 bits (212), Expect = 4e-17
Identities = 40/64 (62%), Positives = 50/64 (78%)
Query: 34 TPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 93
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 113 TKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 172
Query: 94 RQQQ 97
R+Q+
Sbjct: 173 RKQE 176
>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
Length = 217
Score = 86.3 bits (212), Expect = 4e-17
Identities = 41/78 (52%), Positives = 55/78 (70%)
Query: 36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTF SQL LE +F +T YPD F+RE++A ++NL E+RVQVWF+NRRAK R+
Sbjct: 92 RKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRR 151
Query: 96 QQQSGSGTKSRPAKKKSS 113
+++ K+ K S
Sbjct: 152 NERAMLANKNASLLKSYS 169
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.123 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,050,184
Number of Sequences: 37866
Number of extensions: 831756
Number of successful extensions: 18498
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 826
Number of HSP's successfully gapped in prelim test: 949
Number of HSP's that attempted gapping in prelim test: 6892
Number of HSP's gapped (non-prelim): 6759
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.