Guide to the Human Genome
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Name: OTX2 Sequence: fasta or formatted (297aa) NCBI GI: 11119420
Description:

orthodenticle homeobox 2 isoform a

Referenced in:

Homeobox and Related Proteins
Stem Cells and Early Development

Other entries for this name:
alt prot [289aa] orthodenticle homeobox 2 isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.4         22           2
 C cysteine            2.0          6           1
 D aspartate           3.7         11           1
 E glutamate           2.4          7           2
 F phenylalanine       3.0          9           1
 G glycine             6.7         20           2
 H histidine           1.3          4           2
 I isoleucine          1.7          5           1
 K lysine              4.7         14           3
 L leucine             7.4         22           2
 M methionine          3.0          9           2
 N asparagine          3.4         10           1
 P proline             8.1         24           2
 Q glutamine           7.4         22           7
 R arginine            4.7         14           2
 S serine             14.5         43           3
 T threonine           8.4         25           2
 V valine              4.0         12           1
 W tryptophan          1.7          5           1
 Y tyrosine            4.4         13           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   orthodenticle homeobox 2 isoform a 
OTX2                  0.954   orthodenticle homeobox 2 isoform b 
OTX1                  0.517   orthodenticle homeobox 1 
CRX                   0.401   cone-rod homeobox protein 
ARGFX                 0.134   arginine-fifty homeobox 
PHOX2A                0.128   paired-like homeobox 2a 
DRGX                  0.122   dorsal root ganglia homeobox 
PHOX2B                0.120   paired-like homeobox 2b 
PAX6                  0.116   paired box gene 6 isoform a 
PAX6                  0.116   paired box gene 6 isoform b 
PAX6                  0.116   paired box gene 6 isoform a 
PRRX2                 0.115   paired related homeobox 2 
DMBX1                 0.113   diencephalon/mesencephalon homeobox 1 isoform b [Hom...
DMBX1                 0.113   diencephalon/mesencephalon homeobox 1 isoform a [Hom...
PAX3                  0.113   paired box 3 isoform PAX3h 
SHOX                  0.111   short stature homeobox isoform SHOXb 
SHOX                  0.111   short stature homeobox isoform SHOXa 
PAX3                  0.111   paired box 3 isoform PAX3i 
PAX3                  0.111   paired box 3 isoform PAX3e 
PAX3                  0.111   paired box 3 isoform PAX3d 
PAX3                  0.111   paired box 3 isoform PAX3 
OTP                   0.111   PREDICTED: orthopedia homeobox 
OTP                   0.111   orthopedia homeobox 
SHOX2                 0.110   short stature homeobox 2 isoform a 
SHOX2                 0.110   short stature homeobox 2 isoform b 
PITX1                 0.110   paired-like homeodomain transcription factor 1 [Hom...
PAX3                  0.108   paired box 3 isoform PAX3g 
ARX                   0.106   aristaless related homeobox 
PITX3                 0.106   paired-like homeodomain 3 
PRRX1                 0.104   paired mesoderm homeobox 1 isoform pmx-1b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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