Guide to the Human Genome
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Search of human proteins with 20070103

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20070103 TEA domain family member 2 [Homo sapiens]
         (447 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20070103 TEA domain family member 2 [Homo sapiens]                 915   0.0  
gi|46411152 TEA domain family member 4 isoform 1 [Homo sapiens]       538   e-153
gi|11386151 TEA domain family member 1 [Homo sapiens]                 535   e-152
gi|42490753 TEA domain family member 3 [Homo sapiens]                 530   e-150
gi|46411156 TEA domain family member 4 isoform 2 [Homo sapiens]       488   e-138
gi|46411159 TEA domain family member 4 isoform 3 [Homo sapiens]       363   e-100
gi|40548415 dishevelled associated activator of morphogenesis 2 ...    43   7e-04
gi|52485606 formin-like 2 [Homo sapiens]                               42   9e-04
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    41   0.002
gi|253683544 POM121 membrane glycoprotein-like 2 [Homo sapiens]        40   0.003
gi|157168329 formin 1 [Homo sapiens]                                   39   0.007
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int...    39   0.007
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]    39   0.007
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]                      39   0.013
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    38   0.016
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    38   0.016
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    38   0.016
gi|47132519 Ras association and pleckstrin homology domains 1 is...    37   0.028
gi|31652264 RNA binding motif protein 26 [Homo sapiens]                37   0.028
gi|149363685 hypothetical protein LOC23379 [Homo sapiens]              37   0.036
gi|14043024 BCL2-associated athanogene 3 [Homo sapiens]                37   0.036
gi|41350201 epsin 1 isoform c [Homo sapiens]                           37   0.036
gi|194248095 epsin 1 isoform b [Homo sapiens]                          37   0.036
gi|194272148 epsin 1 isoform a [Homo sapiens]                          37   0.036
gi|38373671 SEC24-related protein C [Homo sapiens]                     37   0.036
gi|38373669 SEC24-related protein C [Homo sapiens]                     37   0.036
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    37   0.048
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    37   0.048
gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r...    37   0.048
gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r...    37   0.048

>gi|20070103 TEA domain family member 2 [Homo sapiens]
          Length = 447

 Score =  915 bits (2365), Expect = 0.0
 Identities = 447/447 (100%), Positives = 447/447 (100%)

Query: 1   MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY 60
           MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY
Sbjct: 1   MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY 60

Query: 61  PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK 120
           PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK
Sbjct: 61  PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK 120

Query: 121 DQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPF 180
           DQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPF
Sbjct: 121 DQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPF 180

Query: 181 SQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP 240
           SQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP
Sbjct: 181 SQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP 240

Query: 241 DAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLV 300
           DAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLV
Sbjct: 241 DAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLV 300

Query: 301 KFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVET 360
           KFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVET
Sbjct: 301 KFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVET 360

Query: 361 ERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL 420
           ERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL
Sbjct: 361 ERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL 420

Query: 421 LLCTAYVFEVSTSERGAQHHIYRLVRD 447
           LLCTAYVFEVSTSERGAQHHIYRLVRD
Sbjct: 421 LLCTAYVFEVSTSERGAQHHIYRLVRD 447


>gi|46411152 TEA domain family member 4 isoform 1 [Homo sapiens]
          Length = 434

 Score =  538 bits (1386), Expect = e-153
 Identities = 279/431 (64%), Positives = 326/431 (75%), Gaps = 16/431 (3%)

Query: 19  SEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYG 78
           S EGS   +GGS+        DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYG
Sbjct: 18  SPEGST-ASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYG 76

Query: 79  RNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVSKDKAFQTMATMSSA 138
           RNELIARYIKLRTGKTRTRKQVSSHIQVLARRK+REIQ+KLKDQ +KDKA Q+MA MSSA
Sbjct: 77  RNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKDQAAKDKALQSMAAMSSA 136

Query: 139 QLISAPSLQAKLG-PTGPQASELFQFWSGG-SGPPWNVPDVKPFSQTPFTLSLTPPSTDL 196
           Q+ISA +  + +    GP    +  FW G   G      DVKPFSQ  + +    P   L
Sbjct: 137 QIISATAFHSSMALARGPGRPAVSGFWQGALPGQAGTSHDVKPFSQQTYAVQ---PPLPL 193

Query: 197 PGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQ 256
           PG+E P   +P P   P+PP WQ R + +++L ++EFSAF+E     D+Y +HLFVHI Q
Sbjct: 194 PGFESPAGPAPSPSAPPAPP-WQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQ 252

Query: 257 HCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAG 316
             PS   P LE+VD+RQIYDKFPEKKGGL++L++RGP +AFFLVKFWADLN     E   
Sbjct: 253 SSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDE--- 309

Query: 317 AGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLR 376
                    FYGVSSQYES E+M +TCS+KVCSFGKQVVEKVETE A+ E+G + YR+ R
Sbjct: 310 ------GSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHR 363

Query: 377 SPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERG 436
           SP+CEY++NF+HKL+ LPE+YMMNSVLENFTILQVVTNRDTQE LLC AYVFEVS SE G
Sbjct: 364 SPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHG 423

Query: 437 AQHHIYRLVRD 447
           AQHHIYRLV++
Sbjct: 424 AQHHIYRLVKE 434


>gi|11386151 TEA domain family member 1 [Homo sapiens]
          Length = 411

 Score =  535 bits (1378), Expect = e-152
 Identities = 283/418 (67%), Positives = 322/418 (77%), Gaps = 31/418 (7%)

Query: 40  DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQ 99
           DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQ
Sbjct: 15  DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQ 74

Query: 100 VSSHIQVLARRKSREIQSKLKDQVSKDKAFQTMATMSSAQLISAPSLQAKLG------PT 153
           VSSHIQVLARRKSR+  SKLKDQ +KDKA Q MA MSSAQ++SA ++  KLG      PT
Sbjct: 75  VSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPT 134

Query: 154 GPQASELFQFWSG--GSGPPWNVPDVKPFSQTPFTL--SLTPPSTDLPGYEPPQALSPLP 209
            P A     FW G   +G P +  DVKPF Q  + +  ++T P   +PG+EP  A     
Sbjct: 135 FPGAPG---FWPGMIQTGQPGSSQDVKPFVQQAYPIQPAVTAP---IPGFEPASA----- 183

Query: 210 PPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESV 269
            P PS PAWQ R +GT +L+LVEFSAF+E     DSY +HLFVHI     S   P LESV
Sbjct: 184 -PAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESV 242

Query: 270 DVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGV 329
           D+RQIYDKFPEKKGGL+EL+ +GP +AFFLVKFWADLN     +         +G FYGV
Sbjct: 243 DIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDD---------AGAFYGV 293

Query: 330 SSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHK 389
           +SQYES E+MT+TCS+KVCSFGKQVVEKVETE A+ E+GRFVYR+ RSPMCEY++NF+HK
Sbjct: 294 TSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHK 353

Query: 390 LRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD 447
           L+ LPE+YMMNSVLENFTIL VVTNRDTQE LLC A VFEVS SE GAQHHIYRLV+D
Sbjct: 354 LKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD 411


>gi|42490753 TEA domain family member 3 [Homo sapiens]
          Length = 435

 Score =  530 bits (1364), Expect = e-150
 Identities = 282/445 (63%), Positives = 330/445 (74%), Gaps = 24/445 (5%)

Query: 14  SGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDE 73
           + W  S    E    G EG       DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDE
Sbjct: 4   NSWNASSSPGEAREDGPEGLDKGLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDE 63

Query: 74  GKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK----DQVSKDKAF 129
           GKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLAR+K RE Q  +K    DQVSKDKA 
Sbjct: 64  GKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKDKAL 123

Query: 130 QTMATMSSAQLISAPSLQAKLGPTGPQASELF----QFWSGG---SGPPWNVPDVKPFSQ 182
           Q+MA+MSSAQ++SA  LQ K  P  P    +F    +FWS        P    D+KPF+Q
Sbjct: 124 QSMASMSSAQIVSASVLQNKFSPPSPLPQAVFSTSSRFWSSPPLLGQQPGPSQDIKPFAQ 183

Query: 183 TPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDA 242
             + +    P T L  YEP   L+PLP    S P WQ R + ++RL+L+E+SAF+E    
Sbjct: 184 PAYPIQPPLPPT-LSSYEP---LAPLPSAAASVPVWQDRTIASSRLRLLEYSAFMEVQRD 239

Query: 243 VDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKF 302
            D+Y +HLFVHI Q  P+   PPLE+VDVRQIYDKFPEKKGGL+ELY++GPP+AFFLVKF
Sbjct: 240 PDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKF 299

Query: 303 WADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETER 362
           WADLN   S  + G G       FYGVSSQY S + MT++ S+KVCSFGKQVVEKVETE 
Sbjct: 300 WADLN---STIQEGPGA------FYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEY 350

Query: 363 AQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLL 422
           A+LE+GRFVYR+ RSPMCEY++NF+HKL+ LPE+YMMNSVLENFTILQVVT+RD+QE LL
Sbjct: 351 ARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLL 410

Query: 423 CTAYVFEVSTSERGAQHHIYRLVRD 447
             A+VFEVSTSE GAQHH+Y+LV+D
Sbjct: 411 VIAFVFEVSTSEHGAQHHVYKLVKD 435


>gi|46411156 TEA domain family member 4 isoform 2 [Homo sapiens]
          Length = 391

 Score =  488 bits (1256), Expect = e-138
 Identities = 260/430 (60%), Positives = 300/430 (69%), Gaps = 57/430 (13%)

Query: 19  SEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYG 78
           S EGS   +GGS+        DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYG
Sbjct: 18  SPEGST-ASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYG 76

Query: 79  RNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVSKDKAFQTMATMSSA 138
           RNELIARYIKLRTGKTRTRKQVSSHIQVLARRK+REIQ+KLK                  
Sbjct: 77  RNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLK------------------ 118

Query: 139 QLISAPSLQAKLGPTGPQASELFQFWSGG-SGPPWNVPDVKPFSQTPFTLSLTPPSTDLP 197
                                   FW G   G      DVKPFSQ  + +    P   LP
Sbjct: 119 ------------------------FWQGALPGQAGTSHDVKPFSQQTYAVQ---PPLPLP 151

Query: 198 GYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQH 257
           G+E P   +P P   P+PP WQ R + +++L ++EFSAF+E     D+Y +HLFVHI Q 
Sbjct: 152 GFESPAGPAPSPSAPPAPP-WQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQS 210

Query: 258 CPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGA 317
            PS   P LE+VD+RQIYDKFPEKKGGL++L++RGP +AFFLVKFWADLN     E    
Sbjct: 211 SPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDE---- 266

Query: 318 GGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRS 377
                   FYGVSSQYES E+M +TCS+KVCSFGKQVVEKVETE A+ E+G + YR+ RS
Sbjct: 267 -----GSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRS 321

Query: 378 PMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGA 437
           P+CEY++NF+HKL+ LPE+YMMNSVLENFTILQVVTNRDTQE LLC AYVFEVS SE GA
Sbjct: 322 PLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGA 381

Query: 438 QHHIYRLVRD 447
           QHHIYRLV++
Sbjct: 382 QHHIYRLVKE 391


>gi|46411159 TEA domain family member 4 isoform 3 [Homo sapiens]
          Length = 305

 Score =  363 bits (931), Expect = e-100
 Identities = 186/318 (58%), Positives = 227/318 (71%), Gaps = 15/318 (4%)

Query: 132 MATMSSAQLISAPSLQAKLG-PTGPQASELFQFWSGG-SGPPWNVPDVKPFSQTPFTLSL 189
           MA MSSAQ+ISA +  + +    GP    +  FW G   G      DVKPFSQ  + +  
Sbjct: 1   MAAMSSAQIISATAFHSSMALARGPGRPAVSGFWQGALPGQAGTSHDVKPFSQQTYAVQ- 59

Query: 190 TPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRH 249
             P   LPG+E P   +P P   P+PP WQ R + +++L ++EFSAF+E     D+Y +H
Sbjct: 60  --PPLPLPGFESPAGPAPSPSAPPAPP-WQGRSVASSKLWMLEFSAFLEQQQDPDTYNKH 116

Query: 250 LFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWG 309
           LFVHI Q  PS   P LE+VD+RQIYDKFPEKKGGL++L++RGP +AFFLVKFWADLN  
Sbjct: 117 LFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTN 176

Query: 310 PSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGR 369
              E            FYGVSSQYES E+M +TCS+KVCSFGKQVVEKVETE A+ E+G 
Sbjct: 177 IEDE---------GSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGH 227

Query: 370 FVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFE 429
           + YR+ RSP+CEY++NF+HKL+ LPE+YMMNSVLENFTILQVVTNRDTQE LLC AYVFE
Sbjct: 228 YSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFE 287

Query: 430 VSTSERGAQHHIYRLVRD 447
           VS SE GAQHHIYRLV++
Sbjct: 288 VSASEHGAQHHIYRLVKE 305


>gi|40548415 dishevelled associated activator of morphogenesis 2
           [Homo sapiens]
          Length = 1067

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 14/133 (10%)

Query: 88  KLRTGKTRTRKQVSSHIQVLAR--RKSREIQSKLKDQVSKDKAFQTMATMSSAQLISAPS 145
           +++  + +  K    H+++++R  RK RE ++K    + K++  +T+  M       +  
Sbjct: 440 EVKQWRDQAEKFRKEHMELVSRLERKERECETKT---LEKEEMMRTLNKMKDKLARESQE 496

Query: 146 LQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQ-- 203
           L+   G      ++L +  +G    P       P    P TLS +  + DLP   PP   
Sbjct: 497 LRQARGQVAELVAQLSELSTGPVSSP-------PPPGGPLTLSSSMTTNDLPPPPPPLPF 549

Query: 204 ALSPLPPPTPSPP 216
           A  P PPP P PP
Sbjct: 550 ACCPPPPPPPLPP 562


>gi|52485606 formin-like 2 [Homo sapiens]
          Length = 1092

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 10/105 (9%)

Query: 114 EIQSKLKDQVSKDKAFQTMATMSSAQLISAPSLQA--KLGPTGPQASELFQFWSGGSGPP 171
           E Q  +K Q   D     +  ++S  L     + A   +GPT   AS      SG   PP
Sbjct: 476 EKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAAS------SGPLPPP 529

Query: 172 WNVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPP 216
              P + P S TP T+   P +  +P   PP    P PPP P PP
Sbjct: 530 --PPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPP 572


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 3/75 (4%)

Query: 143 APSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEPP 202
           AP+  A  GP GP  S     W+ G G  +  P++   S  P+     PP    PG  PP
Sbjct: 132 APTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYP---APPPPQAPGAAPP 188

Query: 203 QALSPLPPPTPSPPA 217
                +PP    PPA
Sbjct: 189 VPWGTVPPGAWGPPA 203



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 24/67 (35%), Positives = 28/67 (41%), Gaps = 14/67 (20%)

Query: 162 QFWSGGSGPPWN-------VPDVKPFSQTPFTLSLTPPSTDL-----PGYEPPQALSPLP 209
           Q W G +  PWN       VP   P S TP T+   P  T +     P   PP   +P P
Sbjct: 32  QGWPGSN--PWNNPSAPSSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPPAPFP 89

Query: 210 PPTPSPP 216
           P  PS P
Sbjct: 90  PSGPSCP 96


>gi|253683544 POM121 membrane glycoprotein-like 2 [Homo sapiens]
          Length = 1035

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 40/121 (33%), Positives = 49/121 (40%), Gaps = 23/121 (19%)

Query: 133 ATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPP 192
           AT  +   +  PSL     P G   SEL          P   PD KP   T   + LTP 
Sbjct: 427 ATSVAHSPLKTPSLPT---PPGCSQSELL---------PGTSPDSKP---TATFILLTPT 471

Query: 193 STDLPGYE---PPQAL----SPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDS 245
           S  LP  +   PP       SP+PP  P+PP  Q+  LG         SA   PPDA  +
Sbjct: 472 SPTLPVTDTTWPPSTSQADRSPMPPDPPAPPTIQSTLLGMVSSPTSHLSASA-PPDATSA 530

Query: 246 Y 246
           +
Sbjct: 531 H 531


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 31/88 (35%), Positives = 36/88 (40%), Gaps = 11/88 (12%)

Query: 128 AFQTMATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTL 187
           A Q M  M+S Q  + P   A + P  P  S L      GS  P   P + P S  P   
Sbjct: 630 ALQPMEGMASNQQKALPPPPASIPPPPPLPSGL------GSLSP--APPMPPVSAGP--- 678

Query: 188 SLTPPSTDLPGYEPPQALSPLPPPTPSP 215
            L PP    P   PP +  P PPP P P
Sbjct: 679 PLPPPPPPPPPLPPPSSAGPPPPPPPPP 706



 Score = 32.3 bits (72), Expect = 0.90
 Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 6/47 (12%)

Query: 170 PPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPP 216
           PP ++P   P      +LS  PP        P  A  PLPPP P PP
Sbjct: 648 PPASIPPPPPLPSGLGSLSPAPPMP------PVSAGPPLPPPPPPPP 688


>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
           interacting protein [Homo sapiens]
          Length = 1211

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 5/70 (7%)

Query: 170 PPWNVPDVKPFSQTPF-----TLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLG 224
           PP    D KP S++         +L  P T L    PP    PLPPP P  P   +RGLG
Sbjct: 760 PPLPFHDAKPSSRSSDGSRGPAQALAKPLTQLSHPVPPPPPPPLPPPVPCAPPMLSRGLG 819

Query: 225 TARLQLVEFS 234
             R +    S
Sbjct: 820 HRRSETSHMS 829


>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
          Length = 753

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 4/98 (4%)

Query: 168 SGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGY-EPPQALSPLPPPTPSPPAWQARGLGTA 226
           +G   +V DV P +    +LSL  P    PG  EPPQ L P   P+  PPA  + G G+ 
Sbjct: 398 NGDAESVSDVPPSTGNSASLSL--PLVLQPGLSEPPQPLLPASAPSAPPPA-PSLGPGSQ 454

Query: 227 RLQLVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAP 264
           +       A ++PP+    +      +  +  P P AP
Sbjct: 455 QAAFGNPPALLQPPEVPVPHSTQFAANHQEFLPHPQAP 492


>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
          Length = 547

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 30/119 (25%), Positives = 47/119 (39%), Gaps = 19/119 (15%)

Query: 102 SHIQVLARRKSREIQSKLKDQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQASELF 161
           S   +L R   ++ Q +L++Q  ++                 P+L+ K+   G  +S  +
Sbjct: 343 SMTSILTRNMDKQRQKRLQEQKQQEG------------YDGGPNLRTKVWQRGTPSSSPY 390

Query: 162 QFWSGGSGPPWNVPDVKPFSQT----PFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPP 216
                    PW+ P +    QT    P +   TPP    P   PP +   LPPP P PP
Sbjct: 391 V---SPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPP 446


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 42/137 (30%), Positives = 53/137 (38%), Gaps = 14/137 (10%)

Query: 141 ISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYE 200
           + AP       P  P A+   Q     + PP  VP   P S  P + S TPP    P   
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS-PPMSPSATPP----PQAP 502

Query: 201 PPQALSPL---PPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQH 257
           PP A  PL    PP  +PPA     L T  LQ +       P  A  S    L +     
Sbjct: 503 PPLAAPPLQLAKPPPQAPPA-----LATPPLQALPSPPASFPGQAPFSPSASLPMS-PLA 556

Query: 258 CPSPGAPPLESVDVRQI 274
            P P APP+ +  + Q+
Sbjct: 557 TPPPQAPPVLAAPLLQV 573



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 29/78 (37%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 141 ISAPSLQ-AKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGY 199
           ++AP LQ AK  P  P A       +  S PP + P   PFS +  +L ++P +T  P  
Sbjct: 505 LAAPPLQLAKPPPQAPPALATPPLQALPS-PPASFPGQAPFSPSA-SLPMSPLATP-PPQ 561

Query: 200 EPPQALSPLPPPTPSPPA 217
            PP   +PL    PSPPA
Sbjct: 562 APPVLAAPLLQVPPSPPA 579



 Score = 33.1 bits (74), Expect = 0.53
 Identities = 24/72 (33%), Positives = 29/72 (40%), Gaps = 13/72 (18%)

Query: 181 SQTPFTLSLTPPSTDL------------PGYEPPQALSPLPPPTPSPPAWQARGLGTARL 228
           SQ P TL  TP S+ L            P    P +L  LP P  +PP+     LG+  L
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 374

Query: 229 QLVEFSAFVEPP 240
           Q    S    PP
Sbjct: 375 QATH-SFLPSPP 385


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 42/137 (30%), Positives = 53/137 (38%), Gaps = 14/137 (10%)

Query: 141 ISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYE 200
           + AP       P  P A+   Q     + PP  VP   P S  P + S TPP    P   
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS-PPMSPSATPP----PQAP 463

Query: 201 PPQALSPL---PPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQH 257
           PP A  PL    PP  +PPA     L T  LQ +       P  A  S    L +     
Sbjct: 464 PPLAAPPLQLAKPPPQAPPA-----LATPPLQALPSPPASFPGQAPFSPSASLPMS-PLA 517

Query: 258 CPSPGAPPLESVDVRQI 274
            P P APP+ +  + Q+
Sbjct: 518 TPPPQAPPVLAAPLLQV 534



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 33/120 (27%), Positives = 47/120 (39%), Gaps = 10/120 (8%)

Query: 127 KAFQTMATMSSAQLISAPSLQ----AKLGPTGPQASELFQFWSGGSGPPWN--VPDVKPF 180
           ++  + AT  S+   S PS +    A   P+ P+   L         PP     P + P 
Sbjct: 231 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 290

Query: 181 SQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP 240
           S +P     TP  +  P    P +L  LP P  +PP+     LG+  LQ    S    PP
Sbjct: 291 SSSPLA---TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH-SFLPSPP 346



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 29/78 (37%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 141 ISAPSLQ-AKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGY 199
           ++AP LQ AK  P  P A       +  S PP + P   PFS +  +L ++P +T  P  
Sbjct: 466 LAAPPLQLAKPPPQAPPALATPPLQALPS-PPASFPGQAPFSPSA-SLPMSPLATP-PPQ 522

Query: 200 EPPQALSPLPPPTPSPPA 217
            PP   +PL    PSPPA
Sbjct: 523 APPVLAAPLLQVPPSPPA 540


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 5/75 (6%)

Query: 141 ISAPSLQAKLGPTGPQASELFQ-FWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGY 199
           +S P  ++ + P  P+AS LF  F      PP   P+  P S  P    L+PP  D P  
Sbjct: 581 MSPPPEESPMSPP-PEASRLFPPFEESPLSPP---PEESPLSPPPEASRLSPPPEDSPMS 636

Query: 200 EPPQALSPLPPPTPS 214
            PP+     PPP  S
Sbjct: 637 PPPEESPMSPPPEVS 651



 Score = 37.0 bits (84), Expect = 0.036
 Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 4/48 (8%)

Query: 168 SGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSP 215
           S PP   P   PF ++P    L+PP  +LP   PP+A    PPP  SP
Sbjct: 537 SPPPEASPLSPPFEESP----LSPPPEELPTSPPPEASRLSPPPEESP 580



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 5/73 (6%)

Query: 143 APSLQAKLGPTGPQASELFQ-FWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEP 201
           +P+L+  L P  P+AS L   F      PP   P+  P S  P    L+PP  + P   P
Sbjct: 529 SPALETPLSPP-PEASPLSPPFEESPLSPP---PEELPTSPPPEASRLSPPPEESPMSPP 584

Query: 202 PQALSPLPPPTPS 214
           P+     PPP  S
Sbjct: 585 PEESPMSPPPEAS 597



 Score = 32.3 bits (72), Expect = 0.90
 Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 5/78 (6%)

Query: 141 ISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVK----PFSQTPFTLSLTPPSTDL 196
           +S P  ++ L P  P++S           PP   P       P S  P    L+PP  + 
Sbjct: 494 LSPPPEESPLSPP-PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552

Query: 197 PGYEPPQALSPLPPPTPS 214
           P   PP+ L   PPP  S
Sbjct: 553 PLSPPPEELPTSPPPEAS 570



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 16/42 (38%), Positives = 20/42 (47%)

Query: 174 VPDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSP 215
           +P V   S  P    L+PP  + P   PP+A    PPP  SP
Sbjct: 656 LPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSP 697



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 15/40 (37%), Positives = 18/40 (45%)

Query: 175 PDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPS 214
           P+  P S  P    L+PP  D P   PP+     PPP  S
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDS 714



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 12/75 (16%)

Query: 141 ISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYE 200
           +S P  ++   P  P+AS L         PP   P+  P S  P  L L+ P  + P   
Sbjct: 449 LSPPPEESPTSPP-PEASRL--------SPP---PEELPASPLPEALHLSRPLEESPLSP 496

Query: 201 PPQALSPLPPPTPSP 215
           PP+     PPP  SP
Sbjct: 497 PPEESPLSPPPESSP 511



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 47/189 (24%), Positives = 66/189 (34%), Gaps = 46/189 (24%)

Query: 144  PSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQ 203
            P  QA L P+ P   ++F+        P +  D  P++Q P T    PP        PP+
Sbjct: 2353 PPAQA-LAPSPPSHPDIFR--------PGSYTD--PYAQPPLTPRPQPP--------PPE 2393

Query: 204  ALSPLPPPT-PSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLF---VHISQHCP 259
            +   LPP + PS P                FS     P +  S Q  L    +     CP
Sbjct: 2394 SCCALPPRSLPSDP----------------FSRVPASPQSQSSSQSPLTPRPLSAEAFCP 2437

Query: 260  SPGAPPLESVDVRQIYDKFPEKKGGLRELYD---RGPPHAFFLVKFWADLNWG----PSG 312
            SP  P  +S D        P+ +     L+      PP   F     A  + G    P+ 
Sbjct: 2438 SPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAA 2497

Query: 313  EEAGAGGSI 321
              AG  G +
Sbjct: 2498 LPAGPAGEL 2506



 Score = 29.6 bits (65), Expect = 5.8
 Identities = 14/40 (35%), Positives = 18/40 (45%)

Query: 175 PDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPS 214
           P+V   S  P    L+PP  + P   PP+     PPP  S
Sbjct: 648 PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS 687



 Score = 29.6 bits (65), Expect = 5.8
 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 144  PSLQAKLGPTGPQASELFQ-FWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTD-LPGYEP 201
            P+L+   G   P A++L    +S G GP W+ PD    +Q P   SL P   D + G   
Sbjct: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGP-WDPPDNLAETQKPEQSSLVPGHLDQVNGQVV 4407

Query: 202  PQA--LSPLPPPTPSPPAWQARGL 223
            P+A  LS    P   P A  A+ +
Sbjct: 4408 PEASQLSIKQEPREEPCALGAQSV 4431



 Score = 29.3 bits (64), Expect = 7.6
 Identities = 23/94 (24%), Positives = 39/94 (41%), Gaps = 11/94 (11%)

Query: 88   KLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVSKDKAFQTMATMSS---------- 137
            K++    + RKQ   H  ++A  ++++ Q + + Q  + +    +A   S          
Sbjct: 3573 KIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLP 3632

Query: 138  AQLISAPSLQAKLGPTGPQASELFQFWSGGSGPP 171
             QL+    LQ   GP G QA  L +   GG   P
Sbjct: 3633 GQLLPGHGLQPPQGPPGGQAGGL-RLTPGGMALP 3665


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 174 VPDVKPFSQ--TPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLV 231
           VP + P  +  TP+T S   P    P   PP    P PPP P  P+  A   G+A    V
Sbjct: 606 VPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFV 665

Query: 232 EFSAFVEPPDA 242
           ++S      +A
Sbjct: 666 KYSTITRLQNA 676



 Score = 35.8 bits (81), Expect = 0.081
 Identities = 41/152 (26%), Positives = 56/152 (36%), Gaps = 45/152 (29%)

Query: 141 ISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTP-FTLSLTPPSTDLP-- 197
           I AP+    + P   QA+           PP   P V P  + P F  S  PPS   P  
Sbjct: 785 IPAPTSTKTVAPVVTQAA-----------PPTPTPPVPPAKKQPAFPASYIPPSPPTPPV 833

Query: 198 --------------GYEPPQALSPLP----------PPTPSPPAWQARGLGTARLQLVEF 233
                            PP  LSP+P          PP P+PPA +++      L+ V  
Sbjct: 834 PVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ-----PLKPVPA 888

Query: 234 SAFVEPPDAVDSYQRHLFVHISQHCPSPGAPP 265
           +   + P AV +  +  +   S   PSP  PP
Sbjct: 889 NVAPQSPPAVKAKPK--WQPSSIPVPSPDFPP 918



 Score = 32.3 bits (72), Expect = 0.90
 Identities = 30/103 (29%), Positives = 38/103 (36%), Gaps = 14/103 (13%)

Query: 115 IQSKLKDQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNV 174
           + S +K   S+     T   M S  L   P   A + P  P A +    W   S P  + 
Sbjct: 858 VPSVVKQIASQFPPPPTPPAMESQPLKPVP---ANVAPQSPPAVKAKPKWQPSSIPVPS- 913

Query: 175 PDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPA 217
           PD  P           PP + L    PP +  P PPP P P A
Sbjct: 914 PDFPP----------PPPESSLVFPPPPPSPVPAPPPPPPPTA 946



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 16/72 (22%)

Query: 201 PPQALSPLPPPTPSPPAWQARGLGTARLQ-------LVEFSAFVEPPDAVDSYQRHLFVH 253
           PP  + P PPP P PP     G   A+L+       L +FSA   PP  +   + H   H
Sbjct: 704 PPNGVVPPPPPPPPPP---TPGSAMAQLKPAPCAPSLPQFSA---PPPPL---KIHQVQH 754

Query: 254 ISQHCPSPGAPP 265
           I+Q  P    PP
Sbjct: 755 ITQVAPPTPPPP 766



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 43/155 (27%), Positives = 54/155 (34%), Gaps = 27/155 (17%)

Query: 145 SLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQT-PFTLSLTPP-STDLPGYEPP 202
           S  A+L P  P A  L QF      PP  +  V+  +Q  P T    PP    LP   PP
Sbjct: 723 SAMAQLKPA-PCAPSLPQF--SAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP 779

Query: 203 QALSPLP----------------PPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSY 246
           + L  +P                PPTP+PP   A+         +  S    PP      
Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS----PPTPPVPV 835

Query: 247 QRHLFVHISQHCPSPGAPPLESVD--VRQIYDKFP 279
                      C  P   PL  V   V+QI  +FP
Sbjct: 836 PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP 870



 Score = 29.6 bits (65), Expect = 5.8
 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 10/75 (13%)

Query: 142 SAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEP 201
           S P       P  P++S +F        PP   P   P    P T S TP  +  PG + 
Sbjct: 908 SIPVPSPDFPPPPPESSLVFP-------PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKT 960

Query: 202 PQALSP---LPPPTP 213
            +  SP    PPPTP
Sbjct: 961 SKTSSPGGKKPPPTP 975


>gi|31652264 RNA binding motif protein 26 [Homo sapiens]
          Length = 980

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 29/107 (27%), Positives = 41/107 (38%), Gaps = 13/107 (12%)

Query: 173 NVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQAL---------SPLPPPTPSPPAWQARGL 223
           N+P + PF   P  +   PP    PG  PP  +          P+PPP P PP+      
Sbjct: 324 NLPGMLPFPAQPPVVEGPPP----PGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTG 379

Query: 224 GTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVD 270
               L  ++ S    PP++  S    +      H P P  P L + D
Sbjct: 380 PPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTAD 426


>gi|149363685 hypothetical protein LOC23379 [Homo sapiens]
          Length = 2266

 Score = 37.0 bits (84), Expect = 0.036
 Identities = 47/168 (27%), Positives = 68/168 (40%), Gaps = 25/168 (14%)

Query: 70   LSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVSKDKAF 129
            L   GK   R+++  +    +  KT    +V +H   +A+  S E ++  K Q S+ +  
Sbjct: 1546 LEPSGKNKNRSKISNKDQSNKPVKTSASSRVETHQSEVAQSFSGE-KANTKTQRSQTQTI 1604

Query: 130  QTMA-----------TMSSAQLISAPSLQAKLGP---TGPQASELFQ---FWSGGSGPPW 172
               A           T+S  +    P L   L P   T P+ S+        S  S P  
Sbjct: 1605 LANADTSTPTDCSPDTLSKIRQEVGPPLPPLLAPLIATPPRTSQPLSPLISSSSPSSPAS 1664

Query: 173  NVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQA 220
             V  V PF +TP      PP+   P  E P+  SP P P+PSP A  A
Sbjct: 1665 PVGQVSPFRETP-----VPPAMS-PWPEDPRRASP-PDPSPSPSAASA 1705


>gi|14043024 BCL2-associated athanogene 3 [Homo sapiens]
          Length = 575

 Score = 37.0 bits (84), Expect = 0.036
 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 26/79 (32%)

Query: 147 QAKLGPTGPQASELFQFWSGGSGPPWNVP--------DVKPFSQTPFTLSLTPPSTDLPG 198
           ++K GP GP+             PP ++P        D KP SQ P      PP ++   
Sbjct: 322 ESKPGPVGPEL------------PPGHIPIQVIRKEVDSKPVSQKP------PPPSEKVE 363

Query: 199 YEPPQALSPLPPPTPSPPA 217
            + P A  P PPP+P P A
Sbjct: 364 VKVPPAPVPCPPPSPGPSA 382


>gi|41350201 epsin 1 isoform c [Homo sapiens]
          Length = 550

 Score = 37.0 bits (84), Expect = 0.036
 Identities = 33/93 (35%), Positives = 40/93 (43%), Gaps = 14/93 (15%)

Query: 137 SAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQT-PFTLSLT----P 191
           +A L+   SL ++ GPT P A     F  GG GP        PF    P TL+L      
Sbjct: 452 NAALVDLDSLVSRPGPTPPGAKASNPFLPGG-GPATGPSVTNPFQPAPPATLTLNQLRLS 510

Query: 192 PSTDLPGYEPPQALSPL-------PPPTPSPPA 217
           P   +PG  PP  +SPL       P   P PPA
Sbjct: 511 PVPPVPG-APPTYISPLGGGPGLPPMMPPGPPA 542


>gi|194248095 epsin 1 isoform b [Homo sapiens]
          Length = 576

 Score = 37.0 bits (84), Expect = 0.036
 Identities = 33/93 (35%), Positives = 40/93 (43%), Gaps = 14/93 (15%)

Query: 137 SAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQT-PFTLSLT----P 191
           +A L+   SL ++ GPT P A     F  GG GP        PF    P TL+L      
Sbjct: 478 NAALVDLDSLVSRPGPTPPGAKASNPFLPGG-GPATGPSVTNPFQPAPPATLTLNQLRLS 536

Query: 192 PSTDLPGYEPPQALSPL-------PPPTPSPPA 217
           P   +PG  PP  +SPL       P   P PPA
Sbjct: 537 PVPPVPG-APPTYISPLGGGPGLPPMMPPGPPA 568


>gi|194272148 epsin 1 isoform a [Homo sapiens]
          Length = 662

 Score = 37.0 bits (84), Expect = 0.036
 Identities = 33/93 (35%), Positives = 40/93 (43%), Gaps = 14/93 (15%)

Query: 137 SAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQT-PFTLSLT----P 191
           +A L+   SL ++ GPT P A     F  GG GP        PF    P TL+L      
Sbjct: 564 NAALVDLDSLVSRPGPTPPGAKASNPFLPGG-GPATGPSVTNPFQPAPPATLTLNQLRLS 622

Query: 192 PSTDLPGYEPPQALSPL-------PPPTPSPPA 217
           P   +PG  PP  +SPL       P   P PPA
Sbjct: 623 PVPPVPG-APPTYISPLGGGPGLPPMMPPGPPA 654


>gi|38373671 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 37.0 bits (84), Expect = 0.036
 Identities = 40/136 (29%), Positives = 52/136 (38%), Gaps = 6/136 (4%)

Query: 196 LPGYE--PPQALSPLPPPTPSPPAWQARG-LGTARLQLVEFSAFVEPPDAVDSYQRHLFV 252
           +PGY+  PPQ +S  PP + +PPA  A+   G A             P +    QR   +
Sbjct: 48  VPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQR---L 104

Query: 253 HISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSG 312
             SQ   SP AP      V Q Y   P       +L       A       + L +GP  
Sbjct: 105 PGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPT 164

Query: 313 EEAGAGGSISSGGFYG 328
             A A GS  + G YG
Sbjct: 165 SLASASGSFPNSGLYG 180


>gi|38373669 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 37.0 bits (84), Expect = 0.036
 Identities = 40/136 (29%), Positives = 52/136 (38%), Gaps = 6/136 (4%)

Query: 196 LPGYE--PPQALSPLPPPTPSPPAWQARG-LGTARLQLVEFSAFVEPPDAVDSYQRHLFV 252
           +PGY+  PPQ +S  PP + +PPA  A+   G A             P +    QR   +
Sbjct: 48  VPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQR---L 104

Query: 253 HISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSG 312
             SQ   SP AP      V Q Y   P       +L       A       + L +GP  
Sbjct: 105 PGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPT 164

Query: 313 EEAGAGGSISSGGFYG 328
             A A GS  + G YG
Sbjct: 165 SLASASGSFPNSGLYG 180


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 40/128 (31%), Positives = 47/128 (36%), Gaps = 21/128 (16%)

Query: 182 QTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAW----QARGL----GTARLQLVEF 233
           Q P  L L PP  D PG E      P PPP P PP        RGL    GT+     E 
Sbjct: 671 QPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCCYPSED 730

Query: 234 SAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKK--------GGL 285
           S+  E     D  +    V +  H P  G    E  D     ++  E +        GG 
Sbjct: 731 SSEDE-----DDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGG 785

Query: 286 RELYDRGP 293
           R L  RGP
Sbjct: 786 RFLQGRGP 793



 Score = 29.3 bits (64), Expect = 7.6
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 5/64 (7%)

Query: 6   AGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDI-----EQSFQEALAIY 60
           A A+   G+G  G+  G   G G   GAG   G  A+G  S  +     + SF   L  +
Sbjct: 339 AAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKF 398

Query: 61  PPCG 64
           P CG
Sbjct: 399 PGCG 402


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 40/128 (31%), Positives = 47/128 (36%), Gaps = 21/128 (16%)

Query: 182 QTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAW----QARGL----GTARLQLVEF 233
           Q P  L L PP  D PG E      P PPP P PP        RGL    GT+     E 
Sbjct: 671 QPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCCYPSED 730

Query: 234 SAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKK--------GGL 285
           S+  E     D  +    V +  H P  G    E  D     ++  E +        GG 
Sbjct: 731 SSEDE-----DDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGG 785

Query: 286 RELYDRGP 293
           R L  RGP
Sbjct: 786 RFLQGRGP 793



 Score = 29.3 bits (64), Expect = 7.6
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 5/64 (7%)

Query: 6   AGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDI-----EQSFQEALAIY 60
           A A+   G+G  G+  G   G G   GAG   G  A+G  S  +     + SF   L  +
Sbjct: 339 AAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKF 398

Query: 61  PPCG 64
           P CG
Sbjct: 399 PGCG 402


>gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 353

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 11/127 (8%)

Query: 138 AQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLP 197
           A+  S  S Q    P    A++L+Q   G  GP  ++  V P +     +   P S D  
Sbjct: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTR 201

Query: 198 GYE---PPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHI 254
            +E   PP   + +  P   PP    RGLG+    L+    ++ P  A     R L  H+
Sbjct: 202 SWEGTKPPAKCASVSSPRCLPP----RGLGSPSFLLI----YLSPAPARGEPCRALTGHL 253

Query: 255 SQHCPSP 261
           SQ   +P
Sbjct: 254 SQRHWAP 260


>gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 368

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 11/127 (8%)

Query: 138 AQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLP 197
           A+  S  S Q    P    A++L+Q   G  GP  ++  V P +     +   P S D  
Sbjct: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTR 201

Query: 198 GYE---PPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHI 254
            +E   PP   + +  P   PP    RGLG+    L+    ++ P  A     R L  H+
Sbjct: 202 SWEGTKPPAKCASVSSPRCLPP----RGLGSPSFLLI----YLSPAPARGEPCRALTGHL 253

Query: 255 SQHCPSP 261
           SQ   +P
Sbjct: 254 SQRHWAP 260


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,770,855
Number of Sequences: 37866
Number of extensions: 1190050
Number of successful extensions: 13858
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 346
Number of HSP's that attempted gapping in prelim test: 10928
Number of HSP's gapped (non-prelim): 2491
length of query: 447
length of database: 18,247,518
effective HSP length: 105
effective length of query: 342
effective length of database: 14,271,588
effective search space: 4880883096
effective search space used: 4880883096
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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