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Search of human proteins with 199559532
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|199559532 Abelson helper integration site 1 isoform b [Homo
sapiens]
(1053 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|199559532 Abelson helper integration site 1 isoform b [Homo s... 2155 0.0
gi|199559490 Abelson helper integration site 1 isoform a [Homo s... 2114 0.0
gi|199559438 Abelson helper integration site 1 isoform a [Homo s... 2114 0.0
gi|31542701 Abelson helper integration site 1 isoform a [Homo sa... 2114 0.0
gi|16554629 WD repeat domain 5 [Homo sapiens] 111 3e-24
gi|16554627 WD repeat domain 5 [Homo sapiens] 111 3e-24
gi|23199987 WD repeat domain 5B [Homo sapiens] 111 4e-24
gi|45238858 WD repeat domain 44 protein [Homo sapiens] 92 3e-18
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 80 1e-14
gi|124256480 APG16 autophagy 16-like isoform 1 [Homo sapiens] 74 9e-13
gi|124256478 APG16 autophagy 16-like isoform 2 [Homo sapiens] 74 9e-13
gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo ... 73 2e-12
gi|147904340 WD repeat domain 82 [Homo sapiens] 69 2e-11
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 68 4e-11
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 67 1e-10
gi|26665869 WD repeat domain 51B [Homo sapiens] 67 1e-10
gi|32189425 WD repeat domain 69 [Homo sapiens] 65 3e-10
gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [H... 63 1e-09
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 63 1e-09
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 63 1e-09
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 63 1e-09
gi|53759148 retinoblastoma binding protein 5 [Homo sapiens] 63 1e-09
gi|153791298 mitogen-activated protein kinase organizer 1 [Homo ... 61 6e-09
gi|14150114 mitogen-activated protein kinase organizer 1 [Homo s... 61 6e-09
gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [... 60 8e-09
gi|5174447 guanine nucleotide binding protein (G protein), beta ... 60 1e-08
gi|19913367 transducin beta-like 1Y [Homo sapiens] 59 2e-08
gi|19913365 transducin beta-like 1Y [Homo sapiens] 59 2e-08
gi|15150805 transducin beta-like 1Y [Homo sapiens] 59 2e-08
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens] 59 2e-08
>gi|199559532 Abelson helper integration site 1 isoform b [Homo
sapiens]
Length = 1053
Score = 2155 bits (5583), Expect = 0.0
Identities = 1053/1053 (100%), Positives = 1053/1053 (100%)
Query: 1 MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT 60
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT
Sbjct: 1 MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT 60
Query: 61 SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED 120
SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED
Sbjct: 61 SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED 120
Query: 121 KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET 180
KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
Sbjct: 121 KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET 180
Query: 181 DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE 240
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE
Sbjct: 181 DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE 240
Query: 241 VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK 300
VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK
Sbjct: 241 VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK 300
Query: 301 PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM 360
PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
Sbjct: 301 PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM 360
Query: 361 ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW 420
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW
Sbjct: 361 ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW 420
Query: 421 EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK 480
EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK
Sbjct: 421 EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK 480
Query: 481 LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP 540
LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
Sbjct: 481 LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP 540
Query: 541 DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK 600
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK
Sbjct: 541 DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK 600
Query: 601 HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL 660
HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL
Sbjct: 601 HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL 660
Query: 661 SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS 720
SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
Sbjct: 661 SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS 720
Query: 721 MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL 780
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL
Sbjct: 721 MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL 780
Query: 781 EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA 840
EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA
Sbjct: 781 EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA 840
Query: 841 ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN 900
ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
Sbjct: 841 ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN 900
Query: 901 MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS 960
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS
Sbjct: 901 MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS 960
Query: 961 FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN 1020
FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN
Sbjct: 961 FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN 1020
Query: 1021 MLTAQEILHQFGFTQTDSHFAEFNTCILWWKKH 1053
MLTAQEILHQFGFTQTDSHFAEFNTCILWWKKH
Sbjct: 1021 MLTAQEILHQFGFTQTDSHFAEFNTCILWWKKH 1053
>gi|199559490 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 2114 bits (5477), Expect = 0.0
Identities = 1038/1046 (99%), Positives = 1038/1046 (99%)
Query: 1 MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT 60
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT
Sbjct: 1 MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT 60
Query: 61 SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED 120
SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED
Sbjct: 61 SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED 120
Query: 121 KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET 180
KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
Sbjct: 121 KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET 180
Query: 181 DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE 240
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE
Sbjct: 181 DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE 240
Query: 241 VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK 300
VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK
Sbjct: 241 VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK 300
Query: 301 PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM 360
PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
Sbjct: 301 PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM 360
Query: 361 ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW 420
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW
Sbjct: 361 ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW 420
Query: 421 EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK 480
EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK
Sbjct: 421 EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK 480
Query: 481 LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP 540
LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
Sbjct: 481 LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP 540
Query: 541 DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK 600
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK
Sbjct: 541 DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK 600
Query: 601 HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL 660
HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL
Sbjct: 601 HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL 660
Query: 661 SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS 720
SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
Sbjct: 661 SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS 720
Query: 721 MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL 780
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL
Sbjct: 721 MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL 780
Query: 781 EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA 840
EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA
Sbjct: 781 EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA 840
Query: 841 ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN 900
ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
Sbjct: 841 ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN 900
Query: 901 MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS 960
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS
Sbjct: 901 MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS 960
Query: 961 FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN 1020
FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN
Sbjct: 961 FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN 1020
Query: 1021 MLTAQEILHQFGFTQTDSHFAEFNTC 1046
MLTAQEILHQFGFTQT E C
Sbjct: 1021 MLTAQEILHQFGFTQTGIISIERKPC 1046
>gi|199559438 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 2114 bits (5477), Expect = 0.0
Identities = 1038/1046 (99%), Positives = 1038/1046 (99%)
Query: 1 MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT 60
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT
Sbjct: 1 MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT 60
Query: 61 SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED 120
SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED
Sbjct: 61 SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED 120
Query: 121 KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET 180
KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
Sbjct: 121 KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET 180
Query: 181 DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE 240
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE
Sbjct: 181 DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE 240
Query: 241 VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK 300
VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK
Sbjct: 241 VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK 300
Query: 301 PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM 360
PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
Sbjct: 301 PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM 360
Query: 361 ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW 420
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW
Sbjct: 361 ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW 420
Query: 421 EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK 480
EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK
Sbjct: 421 EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK 480
Query: 481 LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP 540
LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
Sbjct: 481 LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP 540
Query: 541 DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK 600
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK
Sbjct: 541 DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK 600
Query: 601 HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL 660
HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL
Sbjct: 601 HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL 660
Query: 661 SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS 720
SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
Sbjct: 661 SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS 720
Query: 721 MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL 780
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL
Sbjct: 721 MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL 780
Query: 781 EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA 840
EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA
Sbjct: 781 EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA 840
Query: 841 ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN 900
ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
Sbjct: 841 ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN 900
Query: 901 MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS 960
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS
Sbjct: 901 MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS 960
Query: 961 FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN 1020
FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN
Sbjct: 961 FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN 1020
Query: 1021 MLTAQEILHQFGFTQTDSHFAEFNTC 1046
MLTAQEILHQFGFTQT E C
Sbjct: 1021 MLTAQEILHQFGFTQTGIISIERKPC 1046
>gi|31542701 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 2114 bits (5477), Expect = 0.0
Identities = 1038/1046 (99%), Positives = 1038/1046 (99%)
Query: 1 MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT 60
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT
Sbjct: 1 MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETT 60
Query: 61 SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED 120
SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED
Sbjct: 61 SDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEED 120
Query: 121 KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET 180
KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
Sbjct: 121 KQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET 180
Query: 181 DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE 240
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE
Sbjct: 181 DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKE 240
Query: 241 VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK 300
VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK
Sbjct: 241 VPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPK 300
Query: 301 PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM 360
PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
Sbjct: 301 PKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM 360
Query: 361 ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW 420
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW
Sbjct: 361 ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEW 420
Query: 421 EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK 480
EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK
Sbjct: 421 EEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLK 480
Query: 481 LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP 540
LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
Sbjct: 481 LLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP 540
Query: 541 DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK 600
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK
Sbjct: 541 DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNK 600
Query: 601 HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL 660
HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL
Sbjct: 601 HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDL 660
Query: 661 SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS 720
SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
Sbjct: 661 SWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS 720
Query: 721 MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL 780
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL
Sbjct: 721 MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL 780
Query: 781 EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA 840
EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA
Sbjct: 781 EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGA 840
Query: 841 ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN 900
ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
Sbjct: 841 ANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN 900
Query: 901 MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS 960
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS
Sbjct: 901 MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGS 960
Query: 961 FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN 1020
FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN
Sbjct: 961 FQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSN 1020
Query: 1021 MLTAQEILHQFGFTQTDSHFAEFNTC 1046
MLTAQEILHQFGFTQT E C
Sbjct: 1021 MLTAQEILHQFGFTQTGIISIERKPC 1046
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 111 bits (278), Expect = 3e-24
Identities = 84/328 (25%), Positives = 161/328 (49%), Gaps = 33/328 (10%)
Query: 598 PNKHL-FSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNI 656
PN L F+L + + FS NG LA++ A + I ++ G+F + + GH
Sbjct: 33 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADK---LIKIWGAYDGKFEKTISGHKLG 89
Query: 657 IYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLP-HPSFVYTAKFHPAVRELVVT 715
I D++WS D + ++++S D T +IW ++++ + L H ++V+ F+P L+V+
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIW--DVSSGKCLKTLKGHSNYVFCCNFNPQ-SNLIVS 146
Query: 716 GCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYV 775
G +D +RIW V+ + ++ H ++++ F+ +G + S G+ +W+T
Sbjct: 147 GSFDESVRIWDVKTGK----CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDT-- 200
Query: 776 KINDLEHSVHHWTINKEIKET--EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDL-RIL 832
+ + +T + P+S+++ PNGK +L T D+TL++ D +
Sbjct: 201 -------------ASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGK 247
Query: 833 VARKFVGAANYREKIHSTLTPC-GTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIR 891
+ + G N + I + + G ++ +GSED +VY+WN +T E V +
Sbjct: 248 CLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG--HTDVVI 305
Query: 892 DISYHPFENMVAFCAFGQNEPILLYIYD 919
+ HP EN++A A ++ I L+ D
Sbjct: 306 STACHPTENIIASAALENDKTIKLWKSD 333
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 111 bits (278), Expect = 3e-24
Identities = 84/328 (25%), Positives = 161/328 (49%), Gaps = 33/328 (10%)
Query: 598 PNKHL-FSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNI 656
PN L F+L + + FS NG LA++ A + I ++ G+F + + GH
Sbjct: 33 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADK---LIKIWGAYDGKFEKTISGHKLG 89
Query: 657 IYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLP-HPSFVYTAKFHPAVRELVVT 715
I D++WS D + ++++S D T +IW ++++ + L H ++V+ F+P L+V+
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIW--DVSSGKCLKTLKGHSNYVFCCNFNPQ-SNLIVS 146
Query: 716 GCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYV 775
G +D +RIW V+ + ++ H ++++ F+ +G + S G+ +W+T
Sbjct: 147 GSFDESVRIWDVKTGK----CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDT-- 200
Query: 776 KINDLEHSVHHWTINKEIKET--EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDL-RIL 832
+ + +T + P+S+++ PNGK +L T D+TL++ D +
Sbjct: 201 -------------ASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGK 247
Query: 833 VARKFVGAANYREKIHSTLTPC-GTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIR 891
+ + G N + I + + G ++ +GSED +VY+WN +T E V +
Sbjct: 248 CLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG--HTDVVI 305
Query: 892 DISYHPFENMVAFCAFGQNEPILLYIYD 919
+ HP EN++A A ++ I L+ D
Sbjct: 306 STACHPTENIIASAALENDKTIKLWKSD 333
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 111 bits (277), Expect = 4e-24
Identities = 78/304 (25%), Positives = 151/304 (49%), Gaps = 28/304 (9%)
Query: 617 FSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDG 676
FS NG LA++ A R II++ G++ + L GH I D++WS D ++++S D
Sbjct: 49 FSPNGEWLASSSADR---LIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDK 105
Query: 677 TARIWKNEINNTNTFRVLP-HPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAI 735
T ++W ++ + + L H ++V+ F+P L+++G +D ++IW+V+ +
Sbjct: 106 TLKLW--DVRSGKCLKTLKGHSNYVFCCNFNPP-SNLIISGSFDETVKIWEVKTGK---- 158
Query: 736 LVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKE 795
++ H ++++ F+ G + SG G+ +W+ K + +
Sbjct: 159 CLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAA-----------SGQCLKTLVD 207
Query: 796 TEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDL-RILVARKFVGAANYREKIHSTLTPC 854
+ P+S+++ PNGK +L T D+TL++ D R + + G N + I + +
Sbjct: 208 DD--NPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVT 265
Query: 855 -GTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEPI 913
G ++ +GSED +VY+WN +T E V + + HP EN++A A ++ I
Sbjct: 266 GGKWIVSGSEDNLVYIWNLQTKEIVQKLQG--HTDVVISAACHPTENLIASAALENDKTI 323
Query: 914 LLYI 917
L++
Sbjct: 324 KLWM 327
>gi|45238858 WD repeat domain 44 protein [Homo sapiens]
Length = 913
Score = 92.0 bits (227), Expect = 3e-18
Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 14/222 (6%)
Query: 652 GHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRE 711
GH + DLSWSK+ +++L+SS D T R+W I+ H FV FHP
Sbjct: 605 GHTADLLDLSWSKN-YFLLSSSMDKTVRLW--HISRRECLCCFQHIDFVTAIAFHPRDDR 661
Query: 712 LVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVW 771
++G D +R+W + + L + D I + F G + G G + +
Sbjct: 662 YFLSGSLDGKLRLWNIP--DKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFY 719
Query: 772 NTYVKINDLEHSVHHWTINKEIKETEFK-GIPISYLEIHPNGKRLLIHTKDSTLRIMDLR 830
+T EH +H I+ K G I+ +E P ++L+ + DS +R+ DLR
Sbjct: 720 DT-------EHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLR 772
Query: 831 IL-VARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWN 871
L ++ K+ G N +I ++ + T+L +GSED VY+W+
Sbjct: 773 DLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWS 814
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 80.1 bits (196), Expect = 1e-14
Identities = 90/369 (24%), Positives = 158/369 (42%), Gaps = 43/369 (11%)
Query: 550 MMALQEEKGK-----PVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQA-CRIPNKHLF 603
M+ Q+ KG PV +RH + PG + + G C +
Sbjct: 1 MIEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIM 60
Query: 604 SLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSG-RFMRELCGHLNIIYDLSW 662
L+ E +C F NG LA+A R I+L+ + L GH + +L +
Sbjct: 61 LLSGHEGEVYCCKFHPNGSTLASAGFDR---LILLWNVYGDCDNYATLKGHSGAVMELHY 117
Query: 663 SKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVR--ELVVTGCYDS 720
+ D + ++S+D T +W +E R+ H SFV + +PA R +LV TG D
Sbjct: 118 NTDGSMLFSASTDKTVAVWDSE-TGERVKRLKGHTSFVNSC--YPARRGPQLVCTGSDDG 174
Query: 721 MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDL 780
+++W ++R+ +AI Q + + ++ F+ + SG I VW DL
Sbjct: 175 TVKLW--DIRKKAAIQTFQ---NTYQVLAVTFNDTSDQIISGGIDNDIKVW-------DL 222
Query: 781 EHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARK---- 836
+ +T+ ++ L + G LL + D+T+R+ D+R ++
Sbjct: 223 RQNKLTYTMRGHADS-------VTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVK 275
Query: 837 -FVGAANYREK--IHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDI 893
F G + EK + + +P G+ + AGS D VYVW +T + +Y I ++
Sbjct: 276 IFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVW--DTTSRRILYKLPGHAGSINEV 333
Query: 894 SYHPFENMV 902
++HP E ++
Sbjct: 334 AFHPDEPII 342
Score = 32.0 bits (71), Expect = 3.1
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 5/77 (6%)
Query: 609 ERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHY 668
E+ +S +G +AA A R Y +++ S R + +L GH I ++++ D+
Sbjct: 285 EKNLLRCSWSPDGSKIAAGSADRFVY---VWDTTSRRILYKLPGHAGSINEVAFHPDEPI 341
Query: 669 ILTSSSDGTARIWKNEI 685
I+++SSD R++ EI
Sbjct: 342 IISASSD--KRLYMGEI 356
>gi|124256480 APG16 autophagy 16-like isoform 1 [Homo sapiens]
Length = 607
Score = 73.6 bits (179), Expect = 9e-13
Identities = 81/337 (24%), Positives = 145/337 (43%), Gaps = 56/337 (16%)
Query: 571 SVDTEPGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACAS 630
+VDT PG KEV R+P A + + H +NA + FS R+LA
Sbjct: 297 NVDTHPG--SGKEV----RVPATALCVFDAHDGEVNA-------VQFSPGSRLLATGGMD 343
Query: 631 RDGYPIILYEIPSGR--FMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNE---I 685
R + L+E+ + F L G I + + Y+L +S+D +RIW + +
Sbjct: 344 RR---VKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRL 400
Query: 686 NNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKS 745
+T T H V +AKF +V+G +D +++W + +
Sbjct: 401 RHTLT----GHSGKVLSAKFL-LDNARIVSGSHDRTLKLWDLRSK--------------- 440
Query: 746 FINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKE--IKETEFKGIPI 803
+C T +++G IV V + + W I E ++E E G I
Sbjct: 441 ----VCIKT----VFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLG-KI 491
Query: 804 SYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGAANYR---EKIHSTLTPCGTFLFA 860
+ L+++P LL ++D L+++DLR ++ A ++ + +P G+++ A
Sbjct: 492 TALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAA 551
Query: 861 GSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHP 897
GS +G +Y+W+ TG+ + S S I +++ P
Sbjct: 552 GSAEGSLYIWSVLTGKVEKVLSK-QHSSSINAVAWSP 587
Score = 30.4 bits (67), Expect = 9.2
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 713 VVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWN 772
V G + + IW V + +L +Q H S IN++ + G H+ S D V+W
Sbjct: 549 VAAGSAEGSLYIWSVLTGKVEKVLSKQ---HSSSINAVAWSPSGSHVVSVDKGCKAVLWA 605
Query: 773 TY 774
Y
Sbjct: 606 QY 607
>gi|124256478 APG16 autophagy 16-like isoform 2 [Homo sapiens]
Length = 588
Score = 73.6 bits (179), Expect = 9e-13
Identities = 81/337 (24%), Positives = 145/337 (43%), Gaps = 56/337 (16%)
Query: 571 SVDTEPGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACAS 630
+VDT PG KEV R+P A + + H +NA + FS R+LA
Sbjct: 278 NVDTHPG--SGKEV----RVPATALCVFDAHDGEVNA-------VQFSPGSRLLATGGMD 324
Query: 631 RDGYPIILYEIPSGR--FMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNE---I 685
R + L+E+ + F L G I + + Y+L +S+D +RIW + +
Sbjct: 325 RR---VKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRL 381
Query: 686 NNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKS 745
+T T H V +AKF +V+G +D +++W + +
Sbjct: 382 RHTLT----GHSGKVLSAKFL-LDNARIVSGSHDRTLKLWDLRSK--------------- 421
Query: 746 FINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKE--IKETEFKGIPI 803
+C T +++G IV V + + W I E ++E E G I
Sbjct: 422 ----VCIKT----VFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLG-KI 472
Query: 804 SYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGAANYR---EKIHSTLTPCGTFLFA 860
+ L+++P LL ++D L+++DLR ++ A ++ + +P G+++ A
Sbjct: 473 TALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAA 532
Query: 861 GSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHP 897
GS +G +Y+W+ TG+ + S S I +++ P
Sbjct: 533 GSAEGSLYIWSVLTGKVEKVLSK-QHSSSINAVAWSP 568
Score = 30.4 bits (67), Expect = 9.2
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 713 VVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWN 772
V G + + IW V + +L +Q H S IN++ + G H+ S D V+W
Sbjct: 530 VAAGSAEGSLYIWSVLTGKVEKVLSKQ---HSSSINAVAWSPSGSHVVSVDKGCKAVLWA 586
Query: 773 TY 774
Y
Sbjct: 587 QY 588
>gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo
sapiens]
Length = 513
Score = 72.8 bits (177), Expect = 2e-12
Identities = 63/300 (21%), Positives = 136/300 (45%), Gaps = 28/300 (9%)
Query: 614 CLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHL--------NIIYDLSWSKD 665
C FS +G+ L S DG+ I ++ +G+ ++L + + + +S+D
Sbjct: 219 CARFSPDGQYLVTG--SVDGF-IEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRD 275
Query: 666 DHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIW 725
+ T + DG ++WK + H V F + +++ +D IRI
Sbjct: 276 TEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQ-ILSASFDQTIRIH 334
Query: 726 KVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVH 785
++ S +++F H SF+N F +GH++ S G + +WN +K + ++
Sbjct: 335 GLK----SGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWN--MKTTECSNTF- 387
Query: 786 HWTINKEIKETEFKGIPISYLEIHP-NGKRLLIHTKDSTLRIMDLRILVARKF-VGAANY 843
K + T I ++ + + P N + ++ + +T+ IM+++ + R F G
Sbjct: 388 -----KSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREG 442
Query: 844 REKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVA 903
+ + L+P G +++ ED ++Y ++ TG+ + + + I++HP +N++A
Sbjct: 443 GDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLT--VHEKDVIGIAHHPHQNLIA 500
Score = 57.4 bits (137), Expect = 7e-08
Identities = 39/128 (30%), Positives = 68/128 (53%), Gaps = 14/128 (10%)
Query: 571 SVDTE---PGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAA 627
S DTE G ++ K + WK GQ R + A +G CL FS + + +A
Sbjct: 273 SRDTEMLATGAQDGKIKV-WKIQSGQCLRRFER------AHSKGVTCLSFSKDSSQILSA 325
Query: 628 CASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINN 687
+ I ++ + SG+ ++E GH + + + ++++D HYI+++SSDGT +IW +
Sbjct: 326 SFDQT---IRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTE 382
Query: 688 -TNTFRVL 694
+NTF+ L
Sbjct: 383 CSNTFKSL 390
>gi|147904340 WD repeat domain 82 [Homo sapiens]
Length = 313
Score = 69.3 bits (168), Expect = 2e-11
Identities = 77/299 (25%), Positives = 128/299 (42%), Gaps = 28/299 (9%)
Query: 614 CLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSS 673
C DFS NG + + S D I+LY+ G+ R L + + ++ + ++ SS
Sbjct: 26 CFDFSPNGETVIS---SSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSS 82
Query: 674 SDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDS 733
+ I +++ R P S A V + ++G D IR+W +
Sbjct: 83 NKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQ 142
Query: 734 AILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEH--SVHHWTINK 791
++ H FD EG +G V + VK+ DL T
Sbjct: 143 GLM------HLQGKPVCSFDPEGLIFAAG-------VNSEMVKLYDLRSFDKGPFATFKM 189
Query: 792 EIKET-EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMD-LRILVARKFVGAANYRE-KIH 848
+ T E+ G+ S +GK +LI T S +R++D + +V F G AN + +
Sbjct: 190 QYDRTCEWTGLKFSN-----DGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLE 244
Query: 849 STLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHP-FENMVAFCA 906
++ TP F+ GSEDG ++VWN E+G +VA+ D PI + ++P F + C+
Sbjct: 245 ASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVL-DGKHTGPITCLQFNPKFMTFASACS 302
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 68.2 bits (165), Expect = 4e-11
Identities = 57/248 (22%), Positives = 104/248 (41%), Gaps = 12/248 (4%)
Query: 624 LAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSS-DGTARIWK 682
L A DG I ++E+ +G + L GH +++ DLS++ IL S+S D T RIW
Sbjct: 124 LVLATGLNDGQ-IKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWD 182
Query: 683 NEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDV 742
+ + H +VY P ++ + + + +W + S L+R+ +
Sbjct: 183 LNKHGKQIQVLSGHLQWVYCCSISPDC-SMLCSAAGEKSVFLWSMR----SYTLIRKLEG 237
Query: 743 HKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIP 802
H+S + S F + + + +++W+ Y + S+HH ++ + +++
Sbjct: 238 HQSSVVSCDFSPDSALLVTASYDTNVIMWDPYT--GERLRSLHHTQVDPAMDDSDVHISS 295
Query: 803 ISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGS 862
+ + P G L D LRI L + F N + T P G + G+
Sbjct: 296 LRSVCFSPEGLYLATVADDRLLRIWALELKTPIAFAPMTN---GLCCTFFPHGGVIATGT 352
Query: 863 EDGIVYVW 870
DG V W
Sbjct: 353 RDGHVQFW 360
Score = 39.7 bits (91), Expect = 0.015
Identities = 42/190 (22%), Positives = 79/190 (41%), Gaps = 29/190 (15%)
Query: 697 PSFVYTAKFHPAVREL----VVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCF 752
PS A+ HP V ++ + TG D I+IW+V+ + +L+ H+ + L F
Sbjct: 106 PSRKLWARHHPQVPDVSCLVLATGLNDGQIKIWEVQ----TGLLLLNLSGHQDVVRDLSF 161
Query: 753 DTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYL---EIH 809
G +I+V + K ++ W +NK K+ + + ++ I
Sbjct: 162 TPSG---------SLILVSASRDK------TLRIWDLNKHGKQIQVLSGHLQWVYCCSIS 206
Query: 810 PNGKRLLIHTKDSTLRIMDLR-ILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVY 868
P+ L + ++ + +R + RK G + + +P L S D V
Sbjct: 207 PDCSMLCSAAGEKSVFLWSMRSYTLIRKLEG--HQSSVVSCDFSPDSALLVTASYDTNVI 264
Query: 869 VWNPETGEQV 878
+W+P TGE++
Sbjct: 265 MWDPYTGERL 274
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 66.6 bits (161), Expect = 1e-10
Identities = 64/260 (24%), Positives = 108/260 (41%), Gaps = 35/260 (13%)
Query: 620 NGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTAR 679
+GR+LA D + L+ I + L GH + + + + + I+ S G+ R
Sbjct: 32 SGRLLATG---GDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIR 88
Query: 680 IWKNEINNTNTFRVLP-HPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVR 738
+W ++ R L H + + + FHP E V +G D+ I++W + + V
Sbjct: 89 VW--DLEAAKILRTLMGHKANICSLDFHP-YGEFVASGSQDTNIKLWDIRRKG----CVF 141
Query: 739 QFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEF 798
++ H + L F +G + S +H+V W + +EF
Sbjct: 142 RYRGHSQAVRCLRFSPDGKWLASAAD----------------DHTVKLWDLTAGKMMSEF 185
Query: 799 KGI--PISYLEIHPNGKRLLIHTKDSTLRIMDL-RILVARKFVGAANYREKIHSTL-TPC 854
G P++ +E HPN L + D T+R DL + V G + S L P
Sbjct: 186 PGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPG---PVRSVLFNPD 242
Query: 855 GTFLFAGSEDGI-VYVWNPE 873
G L++G +D + VY W PE
Sbjct: 243 GCCLYSGCQDSLRVYGWEPE 262
Score = 48.5 bits (114), Expect = 3e-05
Identities = 50/218 (22%), Positives = 93/218 (42%), Gaps = 35/218 (16%)
Query: 693 VLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCF 752
++ H S V + A L+ TG D + +W + + + H S + S+
Sbjct: 16 IVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSI----NKPNCIMSLTGHTSPVESVRL 71
Query: 753 DTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNG 812
+T + +G +G I VW DLE + K ++ I L+ HP G
Sbjct: 72 NTPEELIVAGSQSGSIRVW-------DLEAA-------KILRTLMGHKANICSLDFHPYG 117
Query: 813 KRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPC------GTFLFAGSEDGI 866
+ + ++D+ +++ D+R RK +R + HS C G +L + ++D
Sbjct: 118 EFVASGSQDTNIKLWDIR----RK---GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
Query: 867 VYVWNPETGEQVAMYSDLP-FKSPIRDISYHPFENMVA 903
V +W+ G+ M S+ P P+ + +HP E ++A
Sbjct: 171 VKLWDLTAGK---MMSEFPGHTGPVNVVEFHPNEYLLA 205
Score = 44.7 bits (104), Expect = 5e-04
Identities = 32/112 (28%), Positives = 57/112 (50%), Gaps = 13/112 (11%)
Query: 614 CLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSS 673
CL FS +G+ LA+A D + + L+++ +G+ M E GH + + + +++ + + S
Sbjct: 152 CLRFSPDGKWLASAA---DDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGS 208
Query: 674 SDGTARIWKNEINNTNTFRVLP----HPSFVYTAKFHPAVRELVVTGCYDSM 721
SD T R W E F+V+ P V + F+P + +GC DS+
Sbjct: 209 SDRTIRFWDLE-----KFQVVSCIEGEPGPVRSVLFNPD-GCCLYSGCQDSL 254
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 66.6 bits (161), Expect = 1e-10
Identities = 66/263 (25%), Positives = 113/263 (42%), Gaps = 26/263 (9%)
Query: 615 LDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSS 674
+ FS +G +LA+A SRD + G+F E H + + +S D ++ T+S
Sbjct: 66 VQFSPHGNLLASA--SRDRTVRLWIPDKRGKFS-EFKAHTAPVRSVDFSADGQFLATASE 122
Query: 675 DGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSA 734
D + ++W + + + H +V AKF P R L+V+ D I+IW ++
Sbjct: 123 DKSIKVW-SMYRQRFLYSLYRHTHWVRCAKFSPDGR-LIVSCSEDKTIKIWDTTNKQ--- 177
Query: 735 ILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIK 794
V F F N + F+ G + S + VW+ V++N L + H+ ++
Sbjct: 178 -CVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWD--VRVNKL---LQHYQVHSG-- 229
Query: 795 ETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPC 854
++ + HP+G L+ + D TL+I+DL L R + + +
Sbjct: 230 -------GVNCISFHPSGNYLITASSDGTLKILDL--LEGRLIYTLQGHTGPVFTVSFSK 280
Query: 855 GTFLFA-GSEDGIVYVWNPETGE 876
G LFA G D V +W E
Sbjct: 281 GGELFASGGADTQVLLWRTNFDE 303
Score = 35.8 bits (81), Expect = 0.22
Identities = 38/184 (20%), Positives = 76/184 (41%), Gaps = 37/184 (20%)
Query: 732 DSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWN--------TYVKINDL--- 780
+ +L R F HK+ I SL G + + +++WN YV D+
Sbjct: 6 EDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTS 65
Query: 781 ---------------EHSVHHWTINKEIKETEFKG--IPISYLEIHPNGKRLLIHTKDST 823
+ +V W +K K +EFK P+ ++ +G+ L ++D +
Sbjct: 66 VQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKS 125
Query: 824 LRIMDLRILVARKFVGAANYREKIH----STLTPCGTFLFAGSEDGIVYVWNPETGEQVA 879
+++ + ++F+ + YR H + +P G + + SED + +W+ + V
Sbjct: 126 IKVWS---MYRQRFLYSL-YRH-THWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVN 180
Query: 880 MYSD 883
+SD
Sbjct: 181 NFSD 184
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 65.5 bits (158), Expect = 3e-10
Identities = 68/271 (25%), Positives = 116/271 (42%), Gaps = 42/271 (15%)
Query: 638 LYEIPSGRFMRELCGHLNIIYDLSWSKD-DHYILTSSSDGTARIWKNEINNT-NTFRVLP 695
L++ SG + L GH N++Y ++++ I T S D T ++W E +TFR
Sbjct: 118 LWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFR--G 175
Query: 696 HPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTE 755
H + + F+P LV TG D+ ++W ++ E+ V H + I SL F+T
Sbjct: 176 HTAEIVCLSFNPQ-STLVATGSMDTTAKLWDIQNGEE----VYTLRGHSAEIISLSFNTS 230
Query: 756 GHHMYSGDCTGVIVVW--NTYVKIN-------DLEHSVHHW--------TINKEIKETE- 797
G + +G +VVW +T K+N ++ + +W +++K K +
Sbjct: 231 GDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDA 290
Query: 798 FKGIPISYLEIHPN----------GKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKI 847
G ++ L H + GK + + D T RI RK + E
Sbjct: 291 TNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFS---AATRKCIAKLEGHEGE 347
Query: 848 HSTLT--PCGTFLFAGSEDGIVYVWNPETGE 876
S ++ P G L GS D +W+ +TG+
Sbjct: 348 ISKISFNPQGNHLLTGSSDKTARIWDAQTGQ 378
Score = 52.8 bits (125), Expect = 2e-06
Identities = 61/266 (22%), Positives = 100/266 (37%), Gaps = 42/266 (15%)
Query: 614 CLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSS 673
CL F+ ++A L++I +G + L GH I LS++ I+T S
Sbjct: 182 CLSFNPQSTLVATGSMDTTAK---LWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGS 238
Query: 674 SDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDS 733
D T +W + ++ H + + +A F+ L++TG D ++W +
Sbjct: 239 FDHTVVVWDADTGRKVNI-LIGHCAEISSASFNWDC-SLILTGSMDKTCKLWDATNGKCV 296
Query: 734 AILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEI 793
A L H I CFD G + + G +++ + K I
Sbjct: 297 ATLTG----HDDEILDSCFDYTGKLIATASADGTARIFSAATR--------------KCI 338
Query: 794 KETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMD------LRILVARK---FVGAANYR 844
+ E IS + +P G LL + D T RI D L++L F A NY+
Sbjct: 339 AKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYK 398
Query: 845 EKIHSTLTPCGTFLFAGSEDGIVYVW 870
G + GS+D +W
Sbjct: 399 ----------GNIVITGSKDNTCRIW 414
Score = 48.5 bits (114), Expect = 3e-05
Identities = 37/174 (21%), Positives = 78/174 (44%), Gaps = 11/174 (6%)
Query: 600 KHLFSLNAGERGCFCLDFSHNG-RILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIY 658
+ +++L L F+ +G RI+ + + +++++ +GR + L GH I
Sbjct: 210 EEVYTLRGHSAEIISLSFNTSGDRIITGSF----DHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 659 DLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCY 718
S++ D ILT S D T ++W + N + H + + F +L+ T
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLW-DATNGKCVATLTGHDDEILDSCF-DYTGKLIATASA 323
Query: 719 DSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWN 772
D RI+ R+ + + + H+ I+ + F+ +G+H+ +G +W+
Sbjct: 324 DGTARIFSAATRK----CIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWD 373
Score = 47.4 bits (111), Expect = 7e-05
Identities = 34/111 (30%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 617 FSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDG 676
F + G+++A A A DG I + + + + +L GH I +S++ +++LT SSD
Sbjct: 311 FDYTGKLIATASA--DGTARI-FSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDK 367
Query: 677 TARIWKNEINNTNTFRVLP-HPSFVYTAKFHPAVRELVVTGCYDSMIRIWK 726
TARIW + +VL H +++ F+ +V+TG D+ RIW+
Sbjct: 368 TARIW--DAQTGQCLQVLEGHTDEIFSCAFNYK-GNIVITGSKDNTCRIWR 415
>gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [Homo
sapiens]
Length = 340
Score = 63.2 bits (152), Expect = 1e-09
Identities = 63/272 (23%), Positives = 115/272 (42%), Gaps = 42/272 (15%)
Query: 645 RFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLP-HPSFVYTA 703
R R L GHL IY + W+ D ++++S DG +W + TN +P S+V T
Sbjct: 46 RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVW--DSYTTNKVHAIPLRSSWVMTC 103
Query: 704 KFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHM---- 759
+ P+ V G D+M I+ ++ RE + + R+ H +++ F + + +
Sbjct: 104 AYAPS-GNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162
Query: 760 --------------------YSGDCTGVIVV--WNTYVKINDLEHSVHHWTINKEIKETE 797
++GDC + V +N ++ + S W + +
Sbjct: 163 DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFIS-GACDASAKLWDVREGTCRQT 221
Query: 798 FKG--IPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTP-- 853
F G I+ + PNG+ + + D++ R+ DLR ++ + ++ E I +T
Sbjct: 222 FTGHESDINAICFFPNGEAICTGSDDASCRLFDLR--ADQELICFSH--ESIICGITSVA 277
Query: 854 ---CGTFLFAGSEDGIVYVWNPETGEQVAMYS 882
G LFAG +D VW+ E+V + S
Sbjct: 278 FSLSGRLLFAGYDDFNCNVWDSMKSERVGILS 309
Score = 35.4 bits (80), Expect = 0.28
Identities = 30/126 (23%), Positives = 56/126 (44%), Gaps = 6/126 (4%)
Query: 638 LYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWK-NEINNTNTFRVLPH 696
L++I +G+ GH L+ S D + ++ + D +A++W E TF H
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTF--TGH 225
Query: 697 PSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEG 756
S + F P E + TG D+ R++ ++R D ++ + I S+ F G
Sbjct: 226 ESDINAICFFPN-GEAICTGSDDASCRLF--DLRADQELICFSHESIICGITSVAFSLSG 282
Query: 757 HHMYSG 762
+++G
Sbjct: 283 RLLFAG 288
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 63.2 bits (152), Expect = 1e-09
Identities = 54/232 (23%), Positives = 91/232 (39%), Gaps = 23/232 (9%)
Query: 598 PNKHLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNII 657
P + + C++FS +G +LA+ SRD I G H +
Sbjct: 12 PQSRAYRFTGHKDAVTCVNFSPSGHLLASG--SRDKTVRIWVPNVKGE-STVFRAHTATV 68
Query: 658 YDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGC 717
+ + D +T+S D T ++W F + H ++V AKF P R L+V+
Sbjct: 69 RSVHFCSDGQSFVTASDDKTVKVWATH-RQKFLFSLSQHINWVRCAKFSPDGR-LIVSAS 126
Query: 718 YDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKI 777
D +++W RE V + H F+ + F G + + + VW+
Sbjct: 127 DDKTVKLWDKSSRE----CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHR 182
Query: 778 NDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDL 829
+ +H +N L HP+G L+ + DSTL+I+DL
Sbjct: 183 LLQHYQLHSAAVNG--------------LSFHPSGNYLITASSDSTLKILDL 220
Score = 47.8 bits (112), Expect = 6e-05
Identities = 56/285 (19%), Positives = 114/285 (40%), Gaps = 34/285 (11%)
Query: 642 PSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNT-FRVLPHPSFV 700
P R R GH + + +++S H + + S D T RIW + +T FR H + V
Sbjct: 12 PQSRAYR-FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRA--HTATV 68
Query: 701 YTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMY 760
+ F + V T D +++W ++ + H +++ F +G +
Sbjct: 69 RSVHFCSDGQSFV-TASDDKTVKVWATHRQK----FLFSLSQHINWVRCAKFSPDGRLIV 123
Query: 761 SGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTK 820
S + +W+ VH + E G ++Y++ HP+G +
Sbjct: 124 SASDDKTVKLWD-----KSSRECVHSYC--------EHGGF-VTYVDFHPSGTCIAAAGM 169
Query: 821 DSTLRIMDL---RILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQ 877
D+T+++ D+ R+L + AA H P G +L S D + + + G
Sbjct: 170 DNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH----PSGNYLITASSDSTLKILDLMEGR- 224
Query: 878 VAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEPILLYIYDFHV 922
+Y+ + P +++ F + G +E ++++ +F +
Sbjct: 225 -LLYTLHGHQGPATTVAFS--RTGEYFASGGSDEQVMVWKSNFDI 266
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 63.2 bits (152), Expect = 1e-09
Identities = 54/232 (23%), Positives = 91/232 (39%), Gaps = 23/232 (9%)
Query: 598 PNKHLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNII 657
P + + C++FS +G +LA+ SRD I G H +
Sbjct: 50 PQSRAYRFTGHKDAVTCVNFSPSGHLLASG--SRDKTVRIWVPNVKGE-STVFRAHTATV 106
Query: 658 YDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGC 717
+ + D +T+S D T ++W F + H ++V AKF P R L+V+
Sbjct: 107 RSVHFCSDGQSFVTASDDKTVKVWATH-RQKFLFSLSQHINWVRCAKFSPDGR-LIVSAS 164
Query: 718 YDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKI 777
D +++W RE V + H F+ + F G + + + VW+
Sbjct: 165 DDKTVKLWDKSSRE----CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHR 220
Query: 778 NDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDL 829
+ +H +N L HP+G L+ + DSTL+I+DL
Sbjct: 221 LLQHYQLHSAAVNG--------------LSFHPSGNYLITASSDSTLKILDL 258
Score = 57.4 bits (137), Expect = 7e-08
Identities = 65/313 (20%), Positives = 129/313 (41%), Gaps = 36/313 (11%)
Query: 614 CLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSS 673
C+DFS N + LA+ S D ++ + P R R GH + + +++S H + + S
Sbjct: 24 CVDFSINTKQLASG--SMDSCLMVWHMKPQSRAYR-FTGHKDAVTCVNFSPSGHLLASGS 80
Query: 674 SDGTARIWKNEINNTNT-FRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMRED 732
D T RIW + +T FR H + V + F + V T D +++W ++
Sbjct: 81 RDKTVRIWVPNVKGESTVFRA--HTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQK- 136
Query: 733 SAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKE 792
+ H +++ F +G + S + +W+ VH +
Sbjct: 137 ---FLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD-----KSSRECVHSYC---- 184
Query: 793 IKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDL---RILVARKFVGAANYREKIHS 849
E G ++Y++ HP+G + D+T+++ D+ R+L + AA H
Sbjct: 185 ----EHGGF-VTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH- 238
Query: 850 TLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQ 909
P G +L S D + + + G +Y+ + P +++ F + G
Sbjct: 239 ---PSGNYLITASSDSTLKILDLMEGR--LLYTLHGHQGPATTVAFS--RTGEYFASGGS 291
Query: 910 NEPILLYIYDFHV 922
+E ++++ +F +
Sbjct: 292 DEQVMVWKSNFDI 304
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 63.2 bits (152), Expect = 1e-09
Identities = 54/232 (23%), Positives = 91/232 (39%), Gaps = 23/232 (9%)
Query: 598 PNKHLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNII 657
P + + C++FS +G +LA+ SRD I G H +
Sbjct: 50 PQSRAYRFTGHKDAVTCVNFSPSGHLLASG--SRDKTVRIWVPNVKGE-STVFRAHTATV 106
Query: 658 YDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGC 717
+ + D +T+S D T ++W F + H ++V AKF P R L+V+
Sbjct: 107 RSVHFCSDGQSFVTASDDKTVKVWATH-RQKFLFSLSQHINWVRCAKFSPDGR-LIVSAS 164
Query: 718 YDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKI 777
D +++W RE V + H F+ + F G + + + VW+
Sbjct: 165 DDKTVKLWDKSSRE----CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHR 220
Query: 778 NDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDL 829
+ +H +N L HP+G L+ + DSTL+I+DL
Sbjct: 221 LLQHYQLHSAAVNG--------------LSFHPSGNYLITASSDSTLKILDL 258
Score = 57.4 bits (137), Expect = 7e-08
Identities = 65/313 (20%), Positives = 129/313 (41%), Gaps = 36/313 (11%)
Query: 614 CLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSS 673
C+DFS N + LA+ S D ++ + P R R GH + + +++S H + + S
Sbjct: 24 CVDFSINTKQLASG--SMDSCLMVWHMKPQSRAYR-FTGHKDAVTCVNFSPSGHLLASGS 80
Query: 674 SDGTARIWKNEINNTNT-FRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMRED 732
D T RIW + +T FR H + V + F + V T D +++W ++
Sbjct: 81 RDKTVRIWVPNVKGESTVFRA--HTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQK- 136
Query: 733 SAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKE 792
+ H +++ F +G + S + +W+ VH +
Sbjct: 137 ---FLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD-----KSSRECVHSYC---- 184
Query: 793 IKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDL---RILVARKFVGAANYREKIHS 849
E G ++Y++ HP+G + D+T+++ D+ R+L + AA H
Sbjct: 185 ----EHGGF-VTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH- 238
Query: 850 TLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQ 909
P G +L S D + + + G +Y+ + P +++ F + G
Sbjct: 239 ---PSGNYLITASSDSTLKILDLMEGR--LLYTLHGHQGPATTVAFS--RTGEYFASGGS 291
Query: 910 NEPILLYIYDFHV 922
+E ++++ +F +
Sbjct: 292 DEQVMVWKSNFDI 304
>gi|53759148 retinoblastoma binding protein 5 [Homo sapiens]
Length = 538
Score = 63.2 bits (152), Expect = 1e-09
Identities = 66/303 (21%), Positives = 126/303 (41%), Gaps = 29/303 (9%)
Query: 617 FSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDG 676
F+ G +LA C DG I++++ + + + H++ + L WS+D H ++++S+D
Sbjct: 32 FNRWGTLLAVGC--NDGR-IVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDN 88
Query: 677 TARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAIL 736
W ++ + + + PS + ++HP + V+ S + + DS +
Sbjct: 89 IVSQW--DVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTL---SDSKHV 143
Query: 737 VRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKET 796
V D FD G ++Y+G+ G I+V T D + V + + T
Sbjct: 144 VLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT-----DSQDLVASFRVTTGTSNT 198
Query: 797 EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTL--TPC 854
I +E G LI+T D +R+ D R ++ G +K+ + TP
Sbjct: 199 ----TAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPW 254
Query: 855 GTFLFAGSEDGIV---------YVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFC 905
F+G + IV Y+W G V + + + D+++HP ++A
Sbjct: 255 KKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGEL-LLDVAWHPVRPIIASI 313
Query: 906 AFG 908
+ G
Sbjct: 314 SSG 316
Score = 32.7 bits (73), Expect = 1.8
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 14/113 (12%)
Query: 812 GKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPC----GTFLFAGSEDGIV 867
G L + D + I D K + A IH + C G L + S D IV
Sbjct: 36 GTLLAVGCNDGRIVIWDFLTRGIAKIISA-----HIHPVCSLCWSRDGHKLVSASTDNIV 90
Query: 868 YVWNPETGEQVAMYSDLPFKSPIRDISYHP-FENMVAFCAFGQNEPILLYIYD 919
W+ +G+ + F SPI + YHP +N V C ++ P++L + D
Sbjct: 91 SQWDVLSGDCDQRFR---FPSPILKVQYHPRDQNKVLVCPM-KSAPVMLTLSD 139
>gi|153791298 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 60.8 bits (146), Expect = 6e-09
Identities = 69/290 (23%), Positives = 123/290 (42%), Gaps = 42/290 (14%)
Query: 640 EIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSF 699
E+P R CG + + ++ D +Y LT SD T ++W N + T H
Sbjct: 12 ELPQKRLKTLDCGQ-GAVRAVRFNVDGNYCLTCGSDKTLKLW-NPLRGTLLRTYSGHGYE 69
Query: 700 VYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHM 759
V A + +G D + +W V S +VR+F H +N++ F+ E +
Sbjct: 70 VLDAA-GSFDNSSLCSGGGDKAVVLWDVA----SGQVVRKFRGHAGKVNTVQFNEEATVI 124
Query: 760 YSGDCTGVIVVWN-------------------TYVKINDLEHSVHHWTINKEIKE----- 795
SG I W+ + VK++D H + +++ ++
Sbjct: 125 LSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVSD--HEILAGSVDGRVRRYDLRM 182
Query: 796 ----TEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRI-LVARKFVGAANYREKIHST 850
+++ G PI+ +G+ L+ + DSTLR++D + ++ G N K+
Sbjct: 183 GQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCC 242
Query: 851 LTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKS-PIRDISYHPFE 899
L+ T + + SEDG V+ W+ G A+ LP S ++ ++YHP E
Sbjct: 243 LSERDTHVVSCSEDGKVFFWDLVEG---ALALALPVGSGVVQSLAYHPTE 289
Score = 34.3 bits (77), Expect = 0.63
Identities = 13/57 (22%), Positives = 32/57 (56%)
Query: 625 AAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIW 681
++ C+ ++L+++ SG+ +R+ GH + + ++++ IL+ S D + R W
Sbjct: 80 SSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCW 136
>gi|14150114 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 60.8 bits (146), Expect = 6e-09
Identities = 69/290 (23%), Positives = 123/290 (42%), Gaps = 42/290 (14%)
Query: 640 EIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSF 699
E+P R CG + + ++ D +Y LT SD T ++W N + T H
Sbjct: 12 ELPQKRLKTLDCGQ-GAVRAVRFNVDGNYCLTCGSDKTLKLW-NPLRGTLLRTYSGHGYE 69
Query: 700 VYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHM 759
V A + +G D + +W V S +VR+F H +N++ F+ E +
Sbjct: 70 VLDAA-GSFDNSSLCSGGGDKAVVLWDVA----SGQVVRKFRGHAGKVNTVQFNEEATVI 124
Query: 760 YSGDCTGVIVVWN-------------------TYVKINDLEHSVHHWTINKEIKE----- 795
SG I W+ + VK++D H + +++ ++
Sbjct: 125 LSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVSD--HEILAGSVDGRVRRYDLRM 182
Query: 796 ----TEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRI-LVARKFVGAANYREKIHST 850
+++ G PI+ +G+ L+ + DSTLR++D + ++ G N K+
Sbjct: 183 GQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCC 242
Query: 851 LTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKS-PIRDISYHPFE 899
L+ T + + SEDG V+ W+ G A+ LP S ++ ++YHP E
Sbjct: 243 LSERDTHVVSCSEDGKVFFWDLVEG---ALALALPVGSGVVQSLAYHPTE 289
Score = 34.3 bits (77), Expect = 0.63
Identities = 13/57 (22%), Positives = 32/57 (56%)
Query: 625 AAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIW 681
++ C+ ++L+++ SG+ +R+ GH + + ++++ IL+ S D + R W
Sbjct: 80 SSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCW 136
>gi|20357529 guanine nucleotide-binding protein, beta-2 subunit
[Homo sapiens]
Length = 340
Score = 60.5 bits (145), Expect = 8e-09
Identities = 57/243 (23%), Positives = 103/243 (42%), Gaps = 28/243 (11%)
Query: 645 RFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLP-HPSFVYTA 703
R R L GHL IY + W D ++++S DG IW + TN +P S+V T
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIW--DSYTTNKVHAIPLRSSWVMTC 103
Query: 704 KFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCF-DTEGHHMYSG 762
+ P+ V G D++ I+ ++ RE + + R+ H +++ F D SG
Sbjct: 104 AYAPS-GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSG 162
Query: 763 DCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGI--PISYLEIHPNGKRLLIHTK 820
D T + W I + F G + L + P+G+ +
Sbjct: 163 DTTCAL------------------WDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 821 DSTLRIMDLRILVARK-FVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVA 879
D+++++ D+R + R+ F+G + + P G GS+D +++ +++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAV--AFFPNGYAFTTGSDDATCRLFDLRADQELL 262
Query: 880 MYS 882
MYS
Sbjct: 263 MYS 265
Score = 33.1 bits (74), Expect = 1.4
Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 6/126 (4%)
Query: 638 LYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWK-NEINNTNTFRVLPH 696
L++I +G+ GH + LS + D ++ + D + ++W + TF + H
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF--IGH 225
Query: 697 PSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEG 756
S + F P TG D+ R++ ++R D +L+ D I S+ F G
Sbjct: 226 ESDINAVAFFPN-GYAFTTGSDDATCRLF--DLRADQELLMYSHDNIICGITSVAFSRSG 282
Query: 757 HHMYSG 762
+ +G
Sbjct: 283 RLLLAG 288
>gi|5174447 guanine nucleotide binding protein (G protein), beta
polypeptide 2-like 1 [Homo sapiens]
Length = 317
Score = 59.7 bits (143), Expect = 1e-08
Identities = 69/311 (22%), Positives = 124/311 (39%), Gaps = 50/311 (16%)
Query: 582 KEVIKWKR--------LPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACASRDG 633
K +I WK +P +A R + + + G F L S +G +
Sbjct: 38 KTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLR--------- 88
Query: 634 YPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRV 693
L+++ +G R GH + +++S D+ I++ S D T ++W T +
Sbjct: 89 ----LWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQD 144
Query: 694 LPHPSFVYTAKFHPAVRELVVTGC-YDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCF 752
H +V +F P ++ C +D ++++W + + L H ++N++
Sbjct: 145 ESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA----NCKLKTNHIGHTGYLNTVTV 200
Query: 753 DTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNG 812
+G SG G ++W DL H +T++ G I+ L PN
Sbjct: 201 SPDGSLCASGGKDGQAMLW-------DLNEGKHLYTLD--------GGDIINALCFSPNR 245
Query: 813 KRLLIHTKDSTLRIMDL--RILV---ARKFVGAANYREKIHST---LTPCGTFLFAGSED 864
L T S ++I DL +I+V ++ + ++ E T + G LFAG D
Sbjct: 246 YWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTD 304
Query: 865 GIVYVWNPETG 875
+V VW G
Sbjct: 305 NLVRVWQVTIG 315
Score = 47.0 bits (110), Expect = 9e-05
Identities = 47/216 (21%), Positives = 92/216 (42%), Gaps = 25/216 (11%)
Query: 669 ILTSSSDGTARIWKNEINNTN---TFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIW 725
IL++S D T +WK + TN R L S + + + ++G +D +R+W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 726 KVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVH 785
+ + R+F H + S+ F ++ + SG I +WNT V
Sbjct: 91 DLT----TGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL--------GVC 138
Query: 786 HWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTK--DSTLRIMDL-RILVARKFVGAAN 842
+T+ E +E+ +S + PN +I + D +++ +L + +G
Sbjct: 139 KYTVQDE-SHSEW----VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTG 193
Query: 843 YREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQV 878
Y + T++P G+ +G +DG +W+ G+ +
Sbjct: 194 YLNTV--TVSPDGSLCASGGKDGQAMLWDLNEGKHL 227
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 59.3 bits (142), Expect = 2e-08
Identities = 68/276 (24%), Positives = 116/276 (42%), Gaps = 35/276 (12%)
Query: 615 LDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSS 674
LD++ +G +LA S DG+ I E +G L H I+ L W+K +Y+L++
Sbjct: 241 LDWNSDGTLLAMG--SYDGFARIWTE--NGNLASTLGQHKGPIFALKWNKKGNYVLSAGV 296
Query: 675 DGTARIWK---NEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSM-IRIWKVEMR 730
D T IW E F P + + C M I + ++
Sbjct: 297 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-------NNMTFASCSTDMCIHVCRLGCD 349
Query: 731 EDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVK--INDLE-HSVHHW 787
V+ F H + +N++ +D G + S + +W+ ++DL+ HS +
Sbjct: 350 HP----VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY 405
Query: 788 TINKEIKETEFKGIPISYLEIHPNGKRLLIHTK-DSTLRIMDLRILVARKFVGAANYREK 846
TI K P +PN +L DST+R+ D+ V + ++E
Sbjct: 406 TI---------KWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTL--MKHQEP 454
Query: 847 IHST-LTPCGTFLFAGSEDGIVYVWNPETGEQVAMY 881
++S +P G +L +GS D V++WN ++G V Y
Sbjct: 455 VYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490
Score = 44.3 bits (103), Expect = 6e-04
Identities = 64/344 (18%), Positives = 130/344 (37%), Gaps = 63/344 (18%)
Query: 640 EIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWK-NEINNTNTFRVLPHPS 698
EIP + L GH + ++ +W+ + + S D TARIW NE +N + +++
Sbjct: 166 EIPPNK-ATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHC 224
Query: 699 FVYTAKFHPAVRE-----------LVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFI 747
P+ ++ L+ G YD RIW ++ L HK I
Sbjct: 225 IREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW-----TENGNLASTLGQHKGPI 279
Query: 748 NSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVH-------HWTIN---------- 790
+L ++ +G+++ S ++W+ + + H W N
Sbjct: 280 FALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDM 339
Query: 791 ----------KEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLR-------ILV 833
+K + ++ ++ P+G L + D TL+I ++ +
Sbjct: 340 CIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQA 399
Query: 834 ARKFVGAANYREKIHSTLTPCGTFLFA-GSEDGIVYVWNPETGEQVAMYSDLPFKSPIRD 892
K + + +T P + + A S D V +W+ E G V ++ + + P+
Sbjct: 400 HSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQG--VCTHTLMKHQEPVYS 457
Query: 893 ISYHPFENMVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGT 936
+++ P +A +F + Y++ ++ Q + Y GT
Sbjct: 458 VAFSPDGKYLASGSFDK------YVHIWNT--QSGSLVHSYQGT 493
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 59.3 bits (142), Expect = 2e-08
Identities = 68/276 (24%), Positives = 116/276 (42%), Gaps = 35/276 (12%)
Query: 615 LDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSS 674
LD++ +G +LA S DG+ I E +G L H I+ L W+K +Y+L++
Sbjct: 241 LDWNSDGTLLAMG--SYDGFARIWTE--NGNLASTLGQHKGPIFALKWNKKGNYVLSAGV 296
Query: 675 DGTARIWK---NEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSM-IRIWKVEMR 730
D T IW E F P + + C M I + ++
Sbjct: 297 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-------NNMTFASCSTDMCIHVCRLGCD 349
Query: 731 EDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVK--INDLE-HSVHHW 787
V+ F H + +N++ +D G + S + +W+ ++DL+ HS +
Sbjct: 350 HP----VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY 405
Query: 788 TINKEIKETEFKGIPISYLEIHPNGKRLLIHTK-DSTLRIMDLRILVARKFVGAANYREK 846
TI K P +PN +L DST+R+ D+ V + ++E
Sbjct: 406 TI---------KWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTL--MKHQEP 454
Query: 847 IHST-LTPCGTFLFAGSEDGIVYVWNPETGEQVAMY 881
++S +P G +L +GS D V++WN ++G V Y
Sbjct: 455 VYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490
Score = 44.3 bits (103), Expect = 6e-04
Identities = 64/344 (18%), Positives = 130/344 (37%), Gaps = 63/344 (18%)
Query: 640 EIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWK-NEINNTNTFRVLPHPS 698
EIP + L GH + ++ +W+ + + S D TARIW NE +N + +++
Sbjct: 166 EIPPNK-ATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHC 224
Query: 699 FVYTAKFHPAVRE-----------LVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFI 747
P+ ++ L+ G YD RIW ++ L HK I
Sbjct: 225 IREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW-----TENGNLASTLGQHKGPI 279
Query: 748 NSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVH-------HWTIN---------- 790
+L ++ +G+++ S ++W+ + + H W N
Sbjct: 280 FALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDM 339
Query: 791 ----------KEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLR-------ILV 833
+K + ++ ++ P+G L + D TL+I ++ +
Sbjct: 340 CIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQA 399
Query: 834 ARKFVGAANYREKIHSTLTPCGTFLFA-GSEDGIVYVWNPETGEQVAMYSDLPFKSPIRD 892
K + + +T P + + A S D V +W+ E G V ++ + + P+
Sbjct: 400 HSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQG--VCTHTLMKHQEPVYS 457
Query: 893 ISYHPFENMVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGT 936
+++ P +A +F + Y++ ++ Q + Y GT
Sbjct: 458 VAFSPDGKYLASGSFDK------YVHIWNT--QSGSLVHSYQGT 493
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 59.3 bits (142), Expect = 2e-08
Identities = 68/276 (24%), Positives = 116/276 (42%), Gaps = 35/276 (12%)
Query: 615 LDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSS 674
LD++ +G +LA S DG+ I E +G L H I+ L W+K +Y+L++
Sbjct: 241 LDWNSDGTLLAMG--SYDGFARIWTE--NGNLASTLGQHKGPIFALKWNKKGNYVLSAGV 296
Query: 675 DGTARIWK---NEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSM-IRIWKVEMR 730
D T IW E F P + + C M I + ++
Sbjct: 297 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-------NNMTFASCSTDMCIHVCRLGCD 349
Query: 731 EDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVK--INDLE-HSVHHW 787
V+ F H + +N++ +D G + S + +W+ ++DL+ HS +
Sbjct: 350 HP----VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY 405
Query: 788 TINKEIKETEFKGIPISYLEIHPNGKRLLIHTK-DSTLRIMDLRILVARKFVGAANYREK 846
TI K P +PN +L DST+R+ D+ V + ++E
Sbjct: 406 TI---------KWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTL--MKHQEP 454
Query: 847 IHST-LTPCGTFLFAGSEDGIVYVWNPETGEQVAMY 881
++S +P G +L +GS D V++WN ++G V Y
Sbjct: 455 VYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490
Score = 44.3 bits (103), Expect = 6e-04
Identities = 64/344 (18%), Positives = 130/344 (37%), Gaps = 63/344 (18%)
Query: 640 EIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWK-NEINNTNTFRVLPHPS 698
EIP + L GH + ++ +W+ + + S D TARIW NE +N + +++
Sbjct: 166 EIPPNK-ATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHC 224
Query: 699 FVYTAKFHPAVRE-----------LVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFI 747
P+ ++ L+ G YD RIW ++ L HK I
Sbjct: 225 IREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW-----TENGNLASTLGQHKGPI 279
Query: 748 NSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVH-------HWTIN---------- 790
+L ++ +G+++ S ++W+ + + H W N
Sbjct: 280 FALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDM 339
Query: 791 ----------KEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLR-------ILV 833
+K + ++ ++ P+G L + D TL+I ++ +
Sbjct: 340 CIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQA 399
Query: 834 ARKFVGAANYREKIHSTLTPCGTFLFA-GSEDGIVYVWNPETGEQVAMYSDLPFKSPIRD 892
K + + +T P + + A S D V +W+ E G V ++ + + P+
Sbjct: 400 HSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQG--VCTHTLMKHQEPVYS 457
Query: 893 ISYHPFENMVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGT 936
+++ P +A +F + Y++ ++ Q + Y GT
Sbjct: 458 VAFSPDGKYLASGSFDK------YVHIWNT--QSGSLVHSYQGT 493
>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
Length = 631
Score = 58.9 bits (141), Expect = 2e-08
Identities = 53/235 (22%), Positives = 96/235 (40%), Gaps = 24/235 (10%)
Query: 638 LYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVL-PH 696
L+++ G + GH ++ +W +++ +SS D T++IW ++N+ L H
Sbjct: 420 LWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIW--DVNSERCRCTLYGH 477
Query: 697 PSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEG 756
V + +F P L +T D + IW + I + H IN FD G
Sbjct: 478 TDSVNSIEFFPFSNTL-LTSSADKTLSIWDAR----TGICEQSLYGHMHSINDAIFDPRG 532
Query: 757 HHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLL 816
H + S D GV +W+ + K+ I + P + + +G+ L
Sbjct: 533 HMIASCDACGVTKLWD-FRKL-------------LPIVSIDIGPSPGNEVNFDSSGRVLA 578
Query: 817 IHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWN 871
+ + + ++DL+ K +G N + + G LF+G DG V W+
Sbjct: 579 QASGNGVIHLLDLKSGEIHKLMGHENEAHTV--VFSHDGEILFSGGSDGTVRTWS 631
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,089,547
Number of Sequences: 37866
Number of extensions: 2023914
Number of successful extensions: 11236
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 637
Number of HSP's that attempted gapping in prelim test: 8596
Number of HSP's gapped (non-prelim): 2653
length of query: 1053
length of database: 18,247,518
effective HSP length: 113
effective length of query: 940
effective length of database: 13,968,660
effective search space: 13130540400
effective search space used: 13130540400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.