Guide to the Human Genome
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Search of human proteins with 19923748

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923748 dihydrolipoamide S-succinyltransferase (E2
component of 2-oxo-glutarate complex) [Homo sapiens]
         (453 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923748 dihydrolipoamide S-succinyltransferase (E2 component...   894   0.0  
gi|31711992 dihydrolipoamide S-acetyltransferase [Homo sapiens]       158   8e-39
gi|203098753 pyruvate dehydrogenase complex, component X isoform...   148   9e-36
gi|110671329 dihydrolipoamide branched chain transacylase precur...   145   1e-34
gi|203098816 pyruvate dehydrogenase complex, component X isoform...   143   4e-34
gi|33356148 formin-like 1 [Homo sapiens]                               60   5e-09
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...    49   7e-06
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    49   1e-05
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    49   1e-05
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    49   1e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    49   1e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    48   2e-05
gi|55741677 SET domain containing 1A [Homo sapiens]                    47   4e-05
gi|21071077 dishevelled-associated activator of morphogenesis 1 ...    47   5e-05
gi|110349719 titin isoform N2-A [Homo sapiens]                         46   6e-05
gi|118402590 myosin XV [Homo sapiens]                                  46   6e-05
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...    46   6e-05
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...    46   6e-05
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...    46   6e-05
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     46   6e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   8e-05
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              46   8e-05
gi|145386517 phostensin [Homo sapiens]                                 46   8e-05
gi|199559805 phostensin [Homo sapiens]                                 46   8e-05
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]                      46   8e-05
gi|52485606 formin-like 2 [Homo sapiens]                               45   1e-04
gi|154146199 sal-like 3 [Homo sapiens]                                 45   1e-04
gi|239752280 PREDICTED: similar to family with sequence similari...    45   1e-04
gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo sap...    45   1e-04
gi|11386183 WAS protein family, member 2 [Homo sapiens]                45   1e-04

>gi|19923748 dihydrolipoamide S-succinyltransferase (E2 component of
           2-oxo-glutarate complex) [Homo sapiens]
          Length = 453

 Score =  894 bits (2309), Expect = 0.0
 Identities = 453/453 (100%), Positives = 453/453 (100%)

Query: 1   MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCQGPGYPNSRKVVINNSVFSVRFF 60
           MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCQGPGYPNSRKVVINNSVFSVRFF
Sbjct: 1   MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCQGPGYPNSRKVVINNSVFSVRFF 60

Query: 61  RTTAVCKDDLVTVKTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPAN 120
           RTTAVCKDDLVTVKTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPAN
Sbjct: 61  RTTAVCKDDLVTVKTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPAN 120

Query: 121 GVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPI 180
           GVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPI
Sbjct: 121 GVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPI 180

Query: 181 PTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKE 240
           PTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKE
Sbjct: 181 PTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKE 240

Query: 241 AQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNA 300
           AQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNA
Sbjct: 241 AQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNA 300

Query: 301 VIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELA 360
           VIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELA
Sbjct: 301 VIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELA 360

Query: 361 IEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVAL 420
           IEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVAL
Sbjct: 361 IEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVAL 420

Query: 421 TYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL 453
           TYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL
Sbjct: 421 TYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL 453


>gi|31711992 dihydrolipoamide S-acetyltransferase [Homo sapiens]
          Length = 647

 Score =  158 bits (400), Expect = 8e-39
 Identities = 128/431 (29%), Positives = 197/431 (45%), Gaps = 56/431 (12%)

Query: 73  VKTPAFAESVTEGDV-RWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDG 131
           V  PA + ++T G V RWEK VG+ ++E +++ EIETDK ++       G +  +LVP+G
Sbjct: 221 VLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEG 280

Query: 132 GK-VEGGTPLFTLRKTGA---APAKAKPAEAP---AAAAPKAEPTAAAVPPPAAPI-PTQ 183
            + V  GTPL  + +  A   A A  +P E         P   P  AAVPP   P+ PT 
Sbjct: 281 TRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTP 340

Query: 184 MPPVPSPSQPPSGK----------------PVSAVKPT--------------------VA 207
             P P+    P G+                 ++ VK T                     A
Sbjct: 341 SAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPA 400

Query: 208 PPLAEPGAGKGLRSEHRE-----KMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEM 262
           P    P  G G+            ++ +R+ IAQRL +++ T        +++M  +  +
Sbjct: 401 PAAVVPPTGPGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLV 460

Query: 263 RARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVA 322
           R    +  + +   K+      +KASA A  + P  N+   DT   +     +D+SVAV+
Sbjct: 461 RKELNK--ILEGRSKISVNDFIIKASALACLKVPEANSSWMDTV--IRQNHVVDVSVAVS 516

Query: 323 TPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFG 382
           TP GL+ P++ N        I   +  L  KAR+ +L   +  GGTFTISN G+FG    
Sbjct: 517 TPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNF 576

Query: 383 TPIINPPQSAILGMHGIFDRPVAIGGK--VEVRPMMYVALTYDHRLIDGREAVTFLRKIK 440
           + IINPPQ+ IL +    D+ V    +   +V  MM V L+ DHR++DG     +L + +
Sbjct: 577 SAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFR 636

Query: 441 AAVEDPRVLLL 451
             +E P  +LL
Sbjct: 637 KYLEKPITMLL 647



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 11/143 (7%)

Query: 73  VKTPAFAESVTEGDV-RWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDG 131
           V  P+ + ++  G + RWEK  GD + E +++ E+ETDK +V   S     +  +LV +G
Sbjct: 94  VPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAEG 153

Query: 132 GK--VEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPS 189
            +    G     T+ K     A  K     ++AAP   P AA  P PAA   T  PP PS
Sbjct: 154 TRDVPIGAIICITVGKPEDIEA-FKNYTLDSSAAP--TPQAAPAPTPAA---TASPPTPS 207

Query: 190 PSQPPSGKP--VSAVKPTVAPPL 210
              P S  P  +  + P ++P +
Sbjct: 208 AQAPGSSYPPHMQVLLPALSPTM 230


>gi|203098753 pyruvate dehydrogenase complex, component X isoform 1
           [Homo sapiens]
          Length = 501

 Score =  148 bits (374), Expect = 9e-36
 Identities = 126/468 (26%), Positives = 214/468 (45%), Gaps = 93/468 (19%)

Query: 58  RFFRTTAVCKDDLVTVKTPAFAESVTEGD-VRWEKAVGDTVAEDEVVCEIETDKTSVQVP 116
           R+F +T   + D + +  P+ + ++ EG+ V+W K  G+ V+  + +CEIETDK  V + 
Sbjct: 44  RWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLD 103

Query: 117 SPANGVIEALLVPDGGK-----------VEGGTP---LFTLRKTGAAPAKAKPAEAPAAA 162
           +  +G++  ++V +G K           VE G     +   +  G  P  +KP+E     
Sbjct: 104 ASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSE----P 159

Query: 163 APKAEPTAAAVPPPAAPIP----------------------------------------- 181
            P  EP   ++P     IP                                         
Sbjct: 160 RPSPEP-QISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALK 218

Query: 182 ----------TQMPPVPSPSQPPSG-KPVSAV-----KPTVAPPLAEPGAGKGLRSEHRE 225
                     T+  P P+P+  P+   P+ A         V PP++ PG    + +    
Sbjct: 219 LVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEI 278

Query: 226 KMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFV 285
             + +R+ IA+RL E+++T        + D+  + ++R       L K ++K+      +
Sbjct: 279 PASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQD-----LVKDDIKVSVNDFII 333

Query: 286 KASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIER 345
           KA+A  L++ P VN   D    + +   +IDISVAVAT +GL+ P+I++  A    +I  
Sbjct: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 391

Query: 346 TITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVA 405
           ++  L +KAR  +L  E+  GG+F+ISN G+FG    T +INPPQ+ IL + G F RPV 
Sbjct: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAV-GRF-RPVL 449

Query: 406 I-------GGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDP 446
                     K++ R ++ V ++ D R++D   A  FL+  KA +E+P
Sbjct: 450 KLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497


>gi|110671329 dihydrolipoamide branched chain transacylase precursor
           [Homo sapiens]
          Length = 482

 Score =  145 bits (365), Expect = 1e-34
 Identities = 118/445 (26%), Positives = 190/445 (42%), Gaps = 66/445 (14%)

Query: 59  FFRTTAVCKDDLVTVKTPAFAESVTEGDVR-WEKAVGDTVAEDEVVCEIETDKTSVQVPS 117
           F +TTA  +  +V  K     E + E  V+ W    GDTV++ + +CE+++DK SV + S
Sbjct: 53  FLKTTAALRGQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITS 112

Query: 118 PANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAA---------------- 161
             +GVI+ L          G PL  +       ++    E PA                 
Sbjct: 113 RYDGVIKKLYYNLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTHQEIKGRKTL 172

Query: 162 AAPKA--------------------------------EPTAAAVPPPAAPIPTQMPPVPS 189
           A P                                  E    A+ PP+  +   MPP P 
Sbjct: 173 ATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEI-MPPPPK 231

Query: 190 PSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLT 249
           P       P+   KP V     +    KG             Q+   +   A        
Sbjct: 232 PKDMTV--PILVSKPPVFTGKDKTEPIKGF------------QKAMVKTMSAALKIPHFG 277

Query: 250 TFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEV 309
             +EID++ + ++R   K     +  +KL FM  F+KA++  L + P++NA +D+  + +
Sbjct: 278 YCDEIDLTELVKLREELKPIAFAR-GIKLSFMPFFLKAASLGLLQFPILNASVDENCQNI 336

Query: 310 VYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTF 369
            Y+   +I +A+ T +GL+VP ++NV+  +  DI   +  L +    ++L+  D+ GGTF
Sbjct: 337 TYKASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTF 396

Query: 370 TISNGGVFGSLFGTPIINPPQSAILGMHGIFDRP-VAIGGKVEVRPMMYVALTYDHRLID 428
           T+SN G  G  F  P+I PP+ AI  +  I   P     G+V    +M V+ + DHR+ID
Sbjct: 397 TLSNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVID 456

Query: 429 GREAVTFLRKIKAAVEDPRVLLLDL 453
           G     F    K+ +E+P  +LLDL
Sbjct: 457 GATMSRFSNLWKSYLENPAFMLLDL 481


>gi|203098816 pyruvate dehydrogenase complex, component X isoform 2
           [Homo sapiens]
          Length = 486

 Score =  143 bits (360), Expect = 4e-34
 Identities = 123/457 (26%), Positives = 208/457 (45%), Gaps = 93/457 (20%)

Query: 69  DLVTVKTPAFAESVTEGD-VRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALL 127
           D + +  P+ + ++ EG+ V+W K  G+ V+  + +CEIETDK  V + +  +G++  ++
Sbjct: 40  DPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIV 99

Query: 128 VPDGGK-----------VEGGTP---LFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAV 173
           V +G K           VE G     +   +  G  P  +KP+E      P  EP   ++
Sbjct: 100 VEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSE----PRPSPEP-QISI 154

Query: 174 PPPAAPIP---------------------------------------------------T 182
           P     IP                                                   T
Sbjct: 155 PVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKIT 214

Query: 183 QMPPVPSPSQPPSG-KPVSAV-----KPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQ 236
           +  P P+P+  P+   P+ A         V PP++ PG    + +      + +R+ IA+
Sbjct: 215 ESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAK 274

Query: 237 RLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQP 296
           RL E+++T        + D+  + ++R       L K ++K+      +KA+A  L++ P
Sbjct: 275 RLTESKSTVPHAYATADCDLGAVLKVRQD-----LVKDDIKVSVNDFIIKAAAVTLKQMP 329

Query: 297 VVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARK 356
            VN   D    + +   +IDISVAVAT +GL+ P+I++  A    +I  ++  L +KAR 
Sbjct: 330 DVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARD 387

Query: 357 NELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVAI-------GGK 409
            +L  E+  GG+F+ISN G+FG    T +INPPQ+ IL + G F RPV           K
Sbjct: 388 GKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAV-GRF-RPVLKLTEDEEGNAK 445

Query: 410 VEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDP 446
           ++ R ++ V ++ D R++D   A  FL+  KA +E+P
Sbjct: 446 LQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 482


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 58/201 (28%), Positives = 77/201 (38%), Gaps = 30/201 (14%)

Query: 84  EGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPS----PANGVIEALLVPDGGKVEGGTP 139
           +G +R  +  GD V+       IE    +V  PS    P  GV      PD        P
Sbjct: 486 KGLIRILRGPGDAVS-------IEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAP 538

Query: 140 LFTLRKTGAAPAKAKPAEAPAAAAPKAEP-TAAAVPPPAAPIPTQMPPVPSPSQPPSGK- 197
                     P    P EAP +A P+A P   +  PPPA P+P  +PP P P  PP G  
Sbjct: 539 GAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTD 598

Query: 198 -PVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQR----------LKEAQNTCA 246
            PV    P   PP   P    G R        + ++ I  +          LK +Q T  
Sbjct: 599 GPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNWVALKPSQITGT 658

Query: 247 MLTTFN------EIDMSNIQE 261
           + T  N      E+DMS+ +E
Sbjct: 659 VFTELNDEKVLQELDMSDFEE 679


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 33/121 (27%), Positives = 48/121 (39%), Gaps = 13/121 (10%)

Query: 150  PAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPP 209
            PA++ P+  P +  P   P A   PPP  P P    P+P    PP+ +P          P
Sbjct: 1389 PARSPPSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLP---PPPNLEPAPPSLGDPGEP 1445

Query: 210  LAEPGAGKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEA 269
             A PG   G  S   E +  +     +R K         + + E+D   I   R RH++ 
Sbjct: 1446 AAHPGPSTG-PSTKNENVATLSVSSLERRK---------SRYAELDFEKIMHTRKRHQDM 1495

Query: 270  F 270
            F
Sbjct: 1496 F 1496


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 37/83 (44%), Positives = 42/83 (50%), Gaps = 11/83 (13%)

Query: 149 APAKAKPAEAPAAAAPKAEPTAAAVPPPA-APIPTQMP-------PVPSPSQPPSGKPVS 200
           APA A PA AP AA P A P A AV  PA AP P   P       P P+P+  P+  P  
Sbjct: 144 APAPA-PAPAPVAA-PVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAP 201

Query: 201 AVKPTVAP-PLAEPGAGKGLRSE 222
           A  P  AP   AE GA +G R +
Sbjct: 202 APAPDAAPQESAEQGANQGQRGQ 224


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 37/83 (44%), Positives = 42/83 (50%), Gaps = 11/83 (13%)

Query: 149 APAKAKPAEAPAAAAPKAEPTAAAVPPPA-APIPTQMP-------PVPSPSQPPSGKPVS 200
           APA A PA AP AA P A P A AV  PA AP P   P       P P+P+  P+  P  
Sbjct: 144 APAPA-PAPAPVAA-PVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAP 201

Query: 201 AVKPTVAP-PLAEPGAGKGLRSE 222
           A  P  AP   AE GA +G R +
Sbjct: 202 APAPDAAPQESAEQGANQGQRGQ 224


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 37/83 (44%), Positives = 42/83 (50%), Gaps = 11/83 (13%)

Query: 149 APAKAKPAEAPAAAAPKAEPTAAAVPPPA-APIPTQMP-------PVPSPSQPPSGKPVS 200
           APA A PA AP AA P A P A AV  PA AP P   P       P P+P+  P+  P  
Sbjct: 155 APAPA-PAPAPVAA-PVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAP 212

Query: 201 AVKPTVAP-PLAEPGAGKGLRSE 222
           A  P  AP   AE GA +G R +
Sbjct: 213 APAPDAAPQESAEQGANQGQRGQ 235


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 35/92 (38%), Positives = 40/92 (43%), Gaps = 7/92 (7%)

Query: 125 ALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQM 184
           A L+P       GT + T    GAA   A  A +P AA   A P AA  PPP AP     
Sbjct: 223 AALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLAR 282

Query: 185 PPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAG 216
           PP       P+G P +A  P V PP A    G
Sbjct: 283 PP-----GHPAGPPTAA--PAVPPPAAAQNGG 307



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 30/73 (41%), Positives = 32/73 (43%), Gaps = 6/73 (8%)

Query: 148 AAPAKAKPAEAPAAAAPKAEPTAAAVPP--PAAPIPTQMPPVPSPSQPPSGKPVSAVKPT 205
           AAPA A PA AP    P   P   A PP  PA P PT  P VP P+   +G    A  P 
Sbjct: 259 AAPAPAAPAAAP--PPPPPAPATLARPPGHPAGP-PTAAPAVPPPAAAQNGGSAGAA-PA 314

Query: 206 VAPPLAEPGAGKG 218
            AP    P    G
Sbjct: 315 PAPAAGGPAGVSG 327



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 15/89 (16%)

Query: 131 GGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSP 190
           G  V  G+P       GA PA   PAE    AAP+  P   A P    P   Q P  PSP
Sbjct: 59  GNHVVSGSPAGA---AGAGPAA--PAEGAPGAAPEPPPAGRARPGGGGP---QRPGPPSP 110

Query: 191 SQP--PSG--KPVSAVKPTVAPPLAEPGA 215
            +P  P+G   P + ++P   PP    G+
Sbjct: 111 RRPLVPAGPAPPAAKLRP---PPEGSAGS 136



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 7/98 (7%)

Query: 148 AAPAKAKPAEAPAAAA-------PKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVS 200
           AAPA A P   PA A        P   PTAA   PP A          +P+  P+    +
Sbjct: 264 AAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA 323

Query: 201 AVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRL 238
            V     P  A      G+++E  +++ +     AQ L
Sbjct: 324 GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTL 361



 Score = 33.1 bits (74), Expect = 0.53
 Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 7/87 (8%)

Query: 118 PANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPA 177
           PA     A  VP     + G         GAAPA A  A  PA  + +  P AAA   PA
Sbjct: 287 PAGPPTAAPAVPPPAAAQNGG------SAGAAPAPAPAAGGPAGVSGQPGPGAAAA-APA 339

Query: 178 APIPTQMPPVPSPSQPPSGKPVSAVKP 204
             +  + P     + PP+ + ++A  P
Sbjct: 340 PGVKAESPKRVVQAAPPAAQTLAASGP 366



 Score = 32.7 bits (73), Expect = 0.69
 Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 9/78 (11%)

Query: 142 TLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPP------VPSPSQPPS 195
           TL  +G A   A     P      A P+ AAVPPPA   PT +P         S S+ P+
Sbjct: 360 TLAASGPASTAASMVIGPTMQG--ALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPT 417

Query: 196 GKPVSAVKPTVAPPLAEP 213
               S ++ T+ P +  P
Sbjct: 418 A-TTSGIRATLTPTVLAP 434



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 29/104 (27%), Positives = 37/104 (35%), Gaps = 13/104 (12%)

Query: 116 PSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPP 175
           PSP   ++ A   P   K+          +  A      PA A  AA P+  P   A P 
Sbjct: 108 PSPRRPLVPAGPAPPAAKLRPPP------EGSAGSCAPVPAAAAVAAGPEPAPAGPAKPA 161

Query: 176 PAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKGL 219
             A +  +  P P P   P   P    KP      A PGA + L
Sbjct: 162 GPAALAARAGPGPGPGPGPGPGP-GPGKP------AGPGAAQTL 198



 Score = 30.0 bits (66), Expect = 4.5
 Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 8/59 (13%)

Query: 148 AAPAKAKPAEAPA----AAAPKAEPTAAAVPPPAAPI----PTQMPPVPSPSQPPSGKP 198
           AAPA    AE+P     AA P A+  AA+ P   A      PT    +PSP+  P   P
Sbjct: 336 AAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAP 394


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 38/112 (33%), Positives = 43/112 (38%), Gaps = 9/112 (8%)

Query: 116  PSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPT-AAAVP 174
            PSP          P   K    TP      T  A     P   PA  +PK  PT  AA P
Sbjct: 934  PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993

Query: 175  P-----PAAPIPTQMPPVPSPSQP-PSGKPVSAVKPTVA--PPLAEPGAGKG 218
            P     PA P P   P  P+ + P P G P +   P  A  PP A P + KG
Sbjct: 994  PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG 1045



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 34/117 (29%), Positives = 38/117 (32%), Gaps = 8/117 (6%)

Query: 110  KTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPT 169
            K  +  PSP          P   K    TP      T  A     P   PA   PK  PT
Sbjct: 1206 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265

Query: 170  AAAVPPPAAPIPTQMPP--------VPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKG 218
              A  PP+       PP        V +P  P  G   S  K    PP A P + KG
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 7/76 (9%)

Query: 150 PAKAKPAEAPAAAAPKAEPTAAAVPP-----PAAPIP--TQMPPVPSPSQPPSGKPVSAV 202
           PA   P +APA +   + P  A   P     PA+P P     PP  +P  P  G    + 
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959

Query: 203 KPTVAPPLAEPGAGKG 218
           K    PP A P + KG
Sbjct: 960 KWAPTPPAATPPSPKG 975



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 32/118 (27%), Positives = 43/118 (36%), Gaps = 20/118 (16%)

Query: 117 SPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAK----PAEAPAAAAPKAEPTAAA 172
           +P   V+      +G           L  T ++P KA+    P   PA+ +PK  PT  A
Sbjct: 885 TPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA 944

Query: 173 VPPP------------AAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKG 218
             PP             AP     PP  +P  P  G    + K    PP A P + KG
Sbjct: 945 ATPPSPKGGPATPSPKWAP----TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 36/114 (31%), Positives = 39/114 (34%), Gaps = 13/114 (11%)

Query: 116  PSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPP 175
            PSP          P   K    TP      T  A     P   PA  +PK  PT  AV P
Sbjct: 957  PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP 1016

Query: 176  P-------AAPIP--TQMPPV---PSPSQPPSGKPVSAVKPTV-APPLAEPGAG 216
            P       A P P     PP    PSP   P+  P+    PT  A  L  P  G
Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 35/105 (33%), Positives = 39/105 (37%), Gaps = 9/105 (8%)

Query: 116  PSPANGVIEALLVPDGGKVEGGTPLFTLR--KTGAAPAKAKPAEAPAAAAPKAEPTAAAV 173
            PSP  G   A  +P G      TP  TL   K G A    K A  P AA P +     A 
Sbjct: 1041 PSP-KGSPAATPLPKGAPT---TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPAT 1096

Query: 174  PPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKG 218
            P P       MPP  +P  P  G      K     P A P + KG
Sbjct: 1097 PSPKG---APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 33/117 (28%), Positives = 37/117 (31%), Gaps = 8/117 (6%)

Query: 110  KTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPT 169
            K  +  P P          P   K    TP      T  A     P    A  +PK  PT
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219

Query: 170  AAAVPPP------AAPIPTQMP--PVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKG 218
              A  PP      A P P   P  P  +P  P  G      K    PP A P + KG
Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 28/108 (25%), Positives = 37/108 (34%), Gaps = 5/108 (4%)

Query: 110  KTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPT 169
            K S   P P        + P   K   GTP        +      P+       P A P+
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPK---GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377

Query: 170  AAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAP--PLAEPGA 215
                P    P P + P +PSP   P+   V  + P  AP  P+   GA
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGA 1425



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 36/116 (31%), Positives = 50/116 (43%), Gaps = 18/116 (15%)

Query: 110  KTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAK---AKPA-------EAP 159
            K    +PSP        ++P   K    TP+   R+  A P+K     PA       +AP
Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKAPATPV--TREGAATPSKGDLTPPAVTPVSLKKAP 1447

Query: 160  AAAAPKAEP-TAAAVPPPAAPIPTQMPPVPSPSQPPSGKPV-SAVKPTVAPPLAEP 213
            A +APK  P T ++   P  P  T     PSP +PP+ K V ++  P  AP    P
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTP----PSPKEPPAPKQVATSSSPKKAPATPAP 1499



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 32/111 (28%), Positives = 36/111 (32%), Gaps = 8/111 (7%)

Query: 116  PSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPP 175
            PSP    +     P   K    TP      T  A     P    A   PK  PT  A  P
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156

Query: 176  P------AAPIPTQMP--PVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKG 218
            P      A P P   P  P  +P  P  G    + K     P A P + KG
Sbjct: 1157 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 32/117 (27%), Positives = 37/117 (31%), Gaps = 8/117 (6%)

Query: 110  KTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPT 169
            K  +  P P          P   K    TP      T  A     P    A  +PK  PT
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196

Query: 170  AAAVPPP------AAPIPTQMP--PVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKG 218
              A  PP      A P P   P  P  +P  P  G    + K     P A P + KG
Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1253



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 27/100 (27%), Positives = 31/100 (31%)

Query: 110  KTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPT 169
            K  +  PSP          P   K    TP      T  A     P    A  +PK  PT
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242

Query: 170  AAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPP 209
              A  PP+       PP      PP+  P S       PP
Sbjct: 1243 TPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 6/72 (8%)

Query: 149  APAKAKPAEAPAAAAPKAEPTAAAVPPPA---APIPTQMPPVPSPSQPPSGKPVSAVKPT 205
            APA + P   PA  + K +PT  AV PP+    P P Q+    SP + P+  P     PT
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA-TPAPMGAPT 1504

Query: 206  VAPPLAEPGAGK 217
            +  P   P + K
Sbjct: 1505 L--PAVIPSSPK 1514



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 34/121 (28%), Positives = 44/121 (36%), Gaps = 26/121 (21%)

Query: 116  PSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVP- 174
            PSP        + P   K   G+P  T    GA+     PA  P +  PK  P A  +P 
Sbjct: 1003 PSPKGAPTPPAVTPPSPK---GSPAATPFPKGAS---TPPAATPPS--PKGSPAATPLPK 1054

Query: 175  ----PPAAPIPT-------------QMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGK 217
                 PAA +P+               PP  +P  P  G    + K    PP A P + K
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK 1114

Query: 218  G 218
            G
Sbjct: 1115 G 1115



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 11/82 (13%)

Query: 139  PLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPP---PAAPIPTQM---PPVPSPSQ 192
            P  T+      PA   P EAPA  + K   +  AV P     AP P ++   P V SPS 
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSP 1610

Query: 193  PPSGKPVSAVKPTVAPPLAEPG 214
              +  P     P V PP  E G
Sbjct: 1611 KEAPTP-----PAVTPPSPEKG 1627



 Score = 36.6 bits (83), Expect = 0.048
 Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 20/126 (15%)

Query: 106  IETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAP- 164
            + + K +  +P+P     EA   P   K     P  T      AP+  +    PA  +P 
Sbjct: 1555 VPSPKKTPAIPTPK----EAPATPSS-KEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609

Query: 165  -KAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPV--SAVKPTVAPPLA--------EP 213
             K  PT  AV PP+   P + P  P+P   P+  PV  S++K +   P +         P
Sbjct: 1610 PKEAPTPPAVTPPS---PEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP 1666

Query: 214  GAGKGL 219
             A KGL
Sbjct: 1667 QASKGL 1672



 Score = 36.2 bits (82), Expect = 0.063
 Identities = 31/104 (29%), Positives = 38/104 (36%), Gaps = 6/104 (5%)

Query: 116  PSPANGVIEALLVPDGGKVEGG-TPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVP 174
            PSP  G   A   P G       TP        A P     +  PAA  P  + + AA P
Sbjct: 994  PSPKGG--PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP 1051

Query: 175  PPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKG 218
             P     T    +PSP     G    ++K    PP A P + KG
Sbjct: 1052 LPKGAPTTPAATLPSPK---GGPATPSLKGAPTPPAATPPSPKG 1092



 Score = 35.8 bits (81), Expect = 0.082
 Identities = 30/81 (37%), Positives = 35/81 (43%), Gaps = 14/81 (17%)

Query: 145  KTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPP-AAPIPTQM-PPVPS-----PSQPPSGK 197
            K G A +  K A  P AA P +   +   PPP  AP P  + PP P      P+  PS K
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357

Query: 198  -----PVSAVKPTVAPPLAEP 213
                 P S   PT  PP A P
Sbjct: 1358 GGPTTPSSKEGPT--PPAATP 1376



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 25/75 (33%), Positives = 29/75 (38%), Gaps = 8/75 (10%)

Query: 145  KTGAAPAKAKPAEAPAAAAPKAEPTAAAVPP--PAAPIPTQMPPVPS---PSQPPSGKPV 199
            K G A    K A  P AA P +     A PP   A   P   PP P     + PP G P 
Sbjct: 1091 KGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT 1150

Query: 200  SAVKPTVAPPLAEPG 214
            +   P   PP  + G
Sbjct: 1151 T---PAATPPSPKGG 1162



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 26/95 (27%), Positives = 30/95 (31%), Gaps = 3/95 (3%)

Query: 116  PSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPP 175
            P P          P   K    TP        A      P   PA + PK  PT  A  P
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317

Query: 176  PAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPL 210
            P+   P   P  P P   P+   V+   P   P L
Sbjct: 1318 PS---PKGSPGTPPPKGAPTPPAVTPPSPKGTPTL 1349



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 28/75 (37%), Positives = 30/75 (40%), Gaps = 5/75 (6%)

Query: 145  KTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPP-AAPIPTQMPPVPSPSQPPSGKPVSAVK 203
            K G A    K A  PA   P +     A  PP  AP P    P PSP   P G P     
Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP-PSPKGSP-GTPPPKGA 1332

Query: 204  PTVAPPLAEPGAGKG 218
            PT  PP   P + KG
Sbjct: 1333 PT--PPAVTPPSPKG 1345



 Score = 32.3 bits (72), Expect = 0.91
 Identities = 22/88 (25%), Positives = 34/88 (38%), Gaps = 22/88 (25%)

Query: 153  AKPAEAPAAAAPKAEPTA------------------AAVPPP-AAPIPTQMPPVPSPSQP 193
            + P E PA  + + +P A                  A +PP    P P + P +P+P + 
Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570

Query: 194  PSGKPVSAVKPTVAPPLAEPGAGKGLRS 221
            P+     + K   +PP   P   KG  S
Sbjct: 1571 PA---TPSSKEASSPPAVTPSTYKGAPS 1595



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 28/101 (27%), Positives = 34/101 (33%), Gaps = 12/101 (11%)

Query: 125  ALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKA-----EPTAAAVPPPAAP 179
            A+ VP   K    TP     K   A   +K A +P A  P        P    +PP    
Sbjct: 1552 AMTVPSPKK----TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607

Query: 180  IPTQMPPVPSPSQPPS---GKPVSAVKPTVAPPLAEPGAGK 217
               +  P P    PPS   G    A K T   P   P + K
Sbjct: 1608 PSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLK 1648



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 3/42 (7%)

Query: 153  AKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPP 194
            + P +APA  AP   PT  AV P +   P ++P  PS  + P
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSS---PKEVPATPSSRRDP 1526



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 44/188 (23%), Positives = 62/188 (32%), Gaps = 51/188 (27%)

Query: 135  EGGTPLFTLRKTGAAPAKA--KPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPS--- 189
            +  TPL     T AA  K   KP  A  +AAP    +    P P   +P +   +PS   
Sbjct: 1768 KASTPL-----TAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPG 1822

Query: 190  ----------------------PSQPPSG------------KPVSAVKPTVAP----PLA 211
                                  P +P SG             P SA  P   P    P+ 
Sbjct: 1823 LVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVT 1882

Query: 212  EPGAGKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFL 271
            +   G G  S+  E +  + +   Q   +A    A L    EID   + + +    E   
Sbjct: 1883 KNNKGSGTESDSDESVPELEE---QDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKA 1939

Query: 272  KKHNLKLG 279
            +K   KLG
Sbjct: 1940 RKAMSKLG 1947



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 43/165 (26%), Positives = 58/165 (35%), Gaps = 28/165 (16%)

Query: 73  VKTPAFAESVTEGDVRWEKAVGDTVAE------DEVVCEIETDKTSVQVPSPANGVIEAL 126
           +KT ++A   + G +     +  TVA       D       T K +    + A+  +E  
Sbjct: 621 IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680

Query: 127 --LVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQM 184
             L P    V+ GT L TL     A      A +P        P A  V  P  P     
Sbjct: 681 VSLAPKNHPVKEGT-LTTLPLVPTASENCPVAPSPQNTCA---PLATLVLAPEIP----- 731

Query: 185 PPVPSPSQPPSGKP-----------VSAVKPTVAPPLAEPGAGKG 218
             VPSPS PP+G P            SA+ P  + P   P    G
Sbjct: 732 KSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSG 776



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 3/65 (4%)

Query: 151 AKAKPA--EAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAP 208
           +K  PA   +P   +PK  PT +AV  P +P    +PP  +P+      P     P    
Sbjct: 846 SKDSPATTHSPTPPSPKGAPTPSAV-TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904

Query: 209 PLAEP 213
           P   P
Sbjct: 905 PKQAP 909


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 38/112 (33%), Positives = 48/112 (42%), Gaps = 12/112 (10%)

Query: 114  QVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAK-AKPAEAPAAAAPKAEPTAAA 172
            +VP P    +E   VP   +V  G+P+  L +  A+PA+ A P E    +AP   P   A
Sbjct: 1083 EVPVPTPAPVE---VPVPERV-AGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPA 1138

Query: 173  VPPPAAPIPTQMPPVPSPSQPPSGKPVSAVK-------PTVAPPLAEPGAGK 217
             PP  AP P + P  P P  PP  K    V        P   PP A P   K
Sbjct: 1139 GPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAK 1190



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 40/140 (28%), Positives = 58/140 (41%), Gaps = 9/140 (6%)

Query: 144 RKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVK 203
           R T   P +A   E P A  P AE TA   PP      + +PP PS       +P ++  
Sbjct: 378 RHTSYPPRRATREEPPGA--PFAENTAERFPPSYT---SYLPPEPSRPTDQDYRPPASEA 432

Query: 204 PTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMR 263
           P   PP    G G G  S  RE++ R   R A   +    + A  TT   +  +    + 
Sbjct: 433 PPPEPPEPGGGGGGGGPSPEREEV-RTSPRPASPAR--SGSPAPETTNESVPFAQHSSLD 489

Query: 264 ARHKEAFLKKHNLKLGFMSA 283
           +R  E  LK+   K  F+++
Sbjct: 490 SR-IEMLLKEQRSKFSFLAS 508



 Score = 33.9 bits (76), Expect = 0.31
 Identities = 17/35 (48%), Positives = 17/35 (48%), Gaps = 1/35 (2%)

Query: 175 PPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPP 209
           PP AP P Q PP P P  PP   P  A  P   PP
Sbjct: 594 PPPAPTPPQQPP-PPPPPPPPPPPYLASLPLGYPP 627



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 18/77 (23%)

Query: 154  KPAEAPAAAAPKAE-----PTAAAVP-------PPAAPIPTQ-----MPPVPSPSQPPSG 196
            +PA  P+A+ P  E     P    VP        P  P+P Q      P  P+   PPS 
Sbjct: 1070 RPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSA 1129

Query: 197  KPVSAVKPTVAPPLAEP 213
             P+   +P   PP   P
Sbjct: 1130 -PLRPPEPPAGPPAPAP 1145



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 18/58 (31%), Positives = 20/58 (34%), Gaps = 7/58 (12%)

Query: 159 PAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQP-------PSGKPVSAVKPTVAPP 209
           PA   P+  P     PPP  P    +P    P QP       P G P     P   PP
Sbjct: 596 PAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPP 653



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 7/59 (11%)

Query: 157  EAPAAAAPKAEPTAAAVPPPAAPIPTQMP-PVPSPSQPPSGKPVSAVKPTVAPPLAEPG 214
            E   AA P A P     PP   P+PT  P  VP P +  +G PV+ +    A P    G
Sbjct: 1068 EERPAALPSASP-----PPREVPVPTPAPVEVPVPER-VAGSPVTPLPEQEASPARPAG 1120


>gi|21071077 dishevelled-associated activator of morphogenesis 1
           [Homo sapiens]
          Length = 1078

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 23/62 (37%), Positives = 28/62 (45%)

Query: 158 APAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGK 217
           AP    P + P +   PPP  P+P  M P P P  PP G P     P +   +  PGA  
Sbjct: 535 APGGPFPSSVPGSLLPPPPPPPLPGGMLPPPPPPLPPGGPPPPPGPPPLGAIMPPPGAPM 594

Query: 218 GL 219
           GL
Sbjct: 595 GL 596


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 52/188 (27%), Positives = 77/188 (40%), Gaps = 41/188 (21%)

Query: 67   KDDLVTVKTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDK-TSVQVPSPANGVI-- 123
            +++++ VK PA         V  +K V   ++E+++     T++  SV VP     ++  
Sbjct: 9224 QEEVIEVKVPA---------VHTKKMV---ISEEKMFFASHTEEEVSVTVPEVQKEIVTE 9271

Query: 124  EALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAE-APAAAAPKAEPTAAAVPP-PAAPIP 181
            E + V    +VE         K    P K  P E AP     K EP A  VP  P  P+P
Sbjct: 9272 EKIHVAISKRVEPPP------KVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVP 9325

Query: 182  TQMPPVPSPSQPPSGKP----------------VSAVKPTVAPPLAEPGAGKGLRSEHRE 225
             +  PVP P + P+  P                V   K   APP   P   KG+ +E  E
Sbjct: 9326 EEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTE--E 9383

Query: 226  KMNRMRQR 233
            K+  + QR
Sbjct: 9384 KITIVTQR 9391



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 34/112 (30%), Positives = 42/112 (37%), Gaps = 4/112 (3%)

Query: 115   VPSPANGVIEALLVPD-GGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAV 173
             VP P         VP+   K E   P+   +K    PAK    E P    P+ E     V
Sbjct: 9965  VPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVP--EVPKKPVPE-EKVPVPV 10021

Query: 174   PPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHRE 225
             P      P ++P VP    P    PV A K   APP   P   K L  E ++
Sbjct: 10022 PKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKK 10073



 Score = 35.8 bits (81), Expect = 0.082
 Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 5/86 (5%)

Query: 144   RKTGAAPAK---AKPAEAPAAAAPKAEPTAAAVPPPAAPI--PTQMPPVPSPSQPPSGKP 198
             +K    PAK   A P + P A           VPPP  P   PT++P VP  + P    P
Sbjct: 10508 KKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVP 10567

Query: 199   VSAVKPTVAPPLAEPGAGKGLRSEHR 224
              +      +PP   P A K +  E +
Sbjct: 10568 EAIPPKPESPPPEVPEAPKEVVPEKK 10593



 Score = 35.8 bits (81), Expect = 0.082
 Identities = 21/69 (30%), Positives = 27/69 (39%), Gaps = 2/69 (2%)

Query: 145   KTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKP 204
             K  A P    P        P        +P P   +P   P +P P+  P  KP + VK 
Sbjct: 10973 KKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK-VPEIKPAIPLPAPEPKPKPEAEVK- 11030

Query: 205   TVAPPLAEP 213
             T+ PP  EP
Sbjct: 11031 TIKPPPVEP 11039



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 27/86 (31%), Positives = 33/86 (38%), Gaps = 3/86 (3%)

Query: 128   VPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPV 187
             VP     E   P+   +K  A PAK    E P    P+ +    A     AP P ++P V
Sbjct: 10007 VPKKPVPEEKVPVPVPKKVEAPPAKVP--EVPKKPVPEKKVPVPAPKKVEAP-PAKVPEV 10063

Query: 188   PSPSQPPSGKPVSAVKPTVAPPLAEP 213
             P    P   KP    K   APP   P
Sbjct: 10064 PKKLIPEEKKPTPVPKKVEAPPPKVP 10089



 Score = 33.1 bits (74), Expect = 0.53
 Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 19/139 (13%)

Query: 95    DTVAEDEVVCEIETDKTSVQVPS-PANGVIEAL-LVPDGGKVEGGTPLFTLRKTGAAPAK 152
             + V E +V    + +    +VP  P   V+E    VP   + E   P         AP +
Sbjct: 10755 EVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEE 10814

Query: 153   --AKPAEAPAAAAPKAEPTAAAVPPPAAP------IPTQMPPV------PSPSQPPSGKP 198
               A   E P   A + EP    VPPPA P      IP +  PV      P P +P   K 
Sbjct: 10815 EIAPEEEKPVPVAEEEEPE---VPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKV 10871

Query: 199   VSAVKPTVAPPLAEPGAGK 217
             +   K    PP   P   K
Sbjct: 10872 IEKPKLKPRPPPPPPAPPK 10890



 Score = 32.7 bits (73), Expect = 0.69
 Identities = 41/150 (27%), Positives = 57/150 (38%), Gaps = 9/150 (6%)

Query: 99   EDEVVCEIETDKTSVQV-PSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAK----A 153
            E+E   E E + T  +V   P   V+E  L     +VE      T R+      K    A
Sbjct: 9511 EEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPA 9570

Query: 154  KPAEAPAAAAPKAEPTAAAVPPPAAPIP--TQMPPVPSPSQPPSGKPVSAVKPTVAPPLA 211
            K  E P A  P+A           AP+P   ++PP   P +P    P   V P V   + 
Sbjct: 9571 KIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVI-KME 9629

Query: 212  EPGAGKGLRSEHREKMNRMRQRIAQRLKEA 241
            EP   K +   H +     +  +A   KEA
Sbjct: 9630 EPLPAK-VTERHMQITQEEKVLVAVTKKEA 9658



 Score = 32.7 bits (73), Expect = 0.69
 Identities = 24/81 (29%), Positives = 30/81 (37%), Gaps = 2/81 (2%)

Query: 146   TGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQ--PPSGKPVSAVK 203
             T   P K  PA+ P             VP      PT++P V  P +  P    PV   K
Sbjct: 10457 TKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAK 10516

Query: 204   PTVAPPLAEPGAGKGLRSEHR 224
                APP   P A K +  E +
Sbjct: 10517 KPEAPPPKVPEAPKEVVPEKK 10537



 Score = 32.3 bits (72), Expect = 0.91
 Identities = 17/56 (30%), Positives = 22/56 (39%), Gaps = 1/56 (1%)

Query: 159   PAAAAPKAEPTAAAVPPPAAPIP-TQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEP 213
             P    P+  P    VP    P+P  + P  P P  P + K V   K    PP  +P
Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKP 10546



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 33/125 (26%), Positives = 43/125 (34%), Gaps = 10/125 (8%)

Query: 97    VAEDEVVCEIETDKTSVQVPS--PANGVI--EALLVPDGGKVEGGTPLFTLRKTGAAPAK 152
             V E++V    E      +VP   P   V+  + + VP   K E   P          P K
Sbjct: 10477 VVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEK 10536

Query: 153   AKPAEAPAAAAPKAEPTAAAVPPPAA----PIPTQMPPVPSPSQPPSGKPVSAVKPTVAP 208
               P   P    P+  PT     P AA     +P  +PP P    P   +    V P    
Sbjct: 10537 KVPVPPPKK--PEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKV 10594

Query: 209   PLAEP 213
             P A P
Sbjct: 10595 PAAPP 10599



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 19/56 (33%), Positives = 22/56 (39%), Gaps = 2/56 (3%)

Query: 154   KPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPP 209
             K  EAP A  P+           A P   ++PP   P  P   KPV   KP V  P
Sbjct: 10740 KKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPK--KPVLEEKPAVPVP 10793



 Score = 30.0 bits (66), Expect = 4.5
 Identities = 23/84 (27%), Positives = 29/84 (34%), Gaps = 9/84 (10%)

Query: 150   PAKAKPAEAPAAAAPKAEPTAAAVPPPAAPI---------PTQMPPVPSPSQPPSGKPVS 200
             PA+      PAA      P    VP   AP          P ++P VP    P    P+ 
Sbjct: 10678 PAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLV 10737

Query: 201   AVKPTVAPPLAEPGAGKGLRSEHR 224
               K   APP   P   K +  E +
Sbjct: 10738 VPKKPEAPPAKVPEVPKEVVPEKK 10761



 Score = 29.6 bits (65), Expect = 5.9
 Identities = 21/71 (29%), Positives = 25/71 (35%), Gaps = 6/71 (8%)

Query: 153  AKPAEAPAAAAPKA------EPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTV 206
            AK  EAP A  P+       E     V       P  +P +P    P   KPV   +  V
Sbjct: 9362 AKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEV 9421

Query: 207  APPLAEPGAGK 217
             PP   P   K
Sbjct: 9422 PPPPKVPALPK 9432



 Score = 29.6 bits (65), Expect = 5.9
 Identities = 15/38 (39%), Positives = 17/38 (44%)

Query: 180  IPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGK 217
            IP ++P VP    P   KPV   K   APP   P   K
Sbjct: 9946 IPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPK 9983



 Score = 29.6 bits (65), Expect = 5.9
 Identities = 25/84 (29%), Positives = 28/84 (33%), Gaps = 8/84 (9%)

Query: 139   PLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMP----PVPSPSQPP 194
             P  T R+         P   PA   P  EP     P P A + T  P    P P+P   P
Sbjct: 10992 PTVTKRERKIPEPTKVPEIKPAIPLPAPEPK----PKPEAEVKTIKPPPVEPEPTPIAAP 11047

Query: 195   SGKPVSAVKPTVAPPLAEPGAGKG 218
                PV   K     P  E    KG
Sbjct: 11048 VTVPVVGKKAEAKAPKEEAAKPKG 11071



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 4/58 (6%)

Query: 157  EAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPS--GKPVSAVKPTVAPPLAE 212
            E+P  A P  E     VP    P+P +   VP P + P+   KPV   K  V  P+A+
Sbjct: 9393 ESPPPAVP--EIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAK 9448



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 31/115 (26%), Positives = 40/115 (34%), Gaps = 6/115 (5%)

Query: 113   VQVPSPANGVIEALLVPDGGKV---EGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPT 169
             V VP P    +    VP+  KV   E   P     K  + P +    E P   A + EP 
Sbjct: 10622 VPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV--FEEPEEVALE-EPP 10678

Query: 170   AAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHR 224
             A  V  P    P Q+   P    P    P    K    PP+  P   K +  E +
Sbjct: 10679 AEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKK 10733


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 2/68 (2%)

Query: 148  AAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVA 207
            +A  ++ PAE P A  P+A+PT+    PPA P+  +  P P    P +  P   +KP  A
Sbjct: 2482 SAALRSLPAEKPPA--PEAQPTSVGTGPPAKPVLLRATPKPLAPAPLAKAPRLPIKPVAA 2539

Query: 208  PPLAEPGA 215
            P LA+  A
Sbjct: 2540 PVLAQDQA 2547



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 25/113 (22%)

Query: 138 TPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAA--VPPPAAPIP-TQMPPVPS----- 189
           +P  +LR     P    PA  P +      P  AA  + PP +P+P +  PP P      
Sbjct: 796 SPQLSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPLGLCH 855

Query: 190 ---------PSQPP------SGKPVSAVKPTVAPPLAEPGAGKGLRS--EHRE 225
                    PS+ P      S  P  AVKP V  P   P      R+  EHRE
Sbjct: 856 SPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAWRAPLEHRE 908



 Score = 33.9 bits (76), Expect = 0.31
 Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 14/88 (15%)

Query: 150 PAKAKPAEAPAAAAPKAEPTAAAVPPPAAP------------IPTQMPPVPSPSQPPSGK 197
           P   +P  +    AP   P  + +P PA+P             P  +PP P  S     +
Sbjct: 664 PVPPRPPSSGPPPAPPLSPALSGLPRPASPYGSLRRHPPPWAAPAHVPPAPQASWWAFVE 723

Query: 198 PVSAVKPTVAPP-LAEPGAGKGLRSEHR 224
           P  AV P V P  LA PG     R   R
Sbjct: 724 P-PAVSPEVPPDLLAFPGPRPSFRGSRR 750


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 34/98 (34%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 139  PLFTLRKTGAAPAKAKPAEA-PAAAAPKAEPTAAAVPPPAAPIPTQMPPV---PSPSQPP 194
            P+  + +    PA AKPA A P AA P A   A   PP A    T   PV   P+  +PP
Sbjct: 2690 PVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPP 2749

Query: 195  SG---KPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNR 229
            +    KPV+       P  A+P A K   ++   KM+R
Sbjct: 2750 AAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSR 2787



 Score = 33.5 bits (75), Expect = 0.41
 Identities = 29/98 (29%), Positives = 36/98 (36%), Gaps = 4/98 (4%)

Query: 110  KTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEA--PAAAAPKAE 167
            K +   P+PA  V    +      V    P+     T A P  AKPA    PAAAA K  
Sbjct: 2700 KPAAAKPAPAKPVAAKPVATKMATVR--PPVAVKPATAAKPVAAKPAAVRPPAAAAAKPV 2757

Query: 168  PTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPT 205
             T   VP P A  P    P  +       + V   + T
Sbjct: 2758 ATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEIT 2795


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 34/98 (34%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 139  PLFTLRKTGAAPAKAKPAEA-PAAAAPKAEPTAAAVPPPAAPIPTQMPPV---PSPSQPP 194
            P+  + +    PA AKPA A P AA P A   A   PP A    T   PV   P+  +PP
Sbjct: 2896 PVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPP 2955

Query: 195  SG---KPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNR 229
            +    KPV+       P  A+P A K   ++   KM+R
Sbjct: 2956 AAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSR 2993



 Score = 33.5 bits (75), Expect = 0.41
 Identities = 29/98 (29%), Positives = 36/98 (36%), Gaps = 4/98 (4%)

Query: 110  KTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEA--PAAAAPKAE 167
            K +   P+PA  V    +      V    P+     T A P  AKPA    PAAAA K  
Sbjct: 2906 KPAAAKPAPAKPVAAKPVATKMATVR--PPVAVKPATAAKPVAAKPAAVRPPAAAAAKPV 2963

Query: 168  PTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPT 205
             T   VP P A  P    P  +       + V   + T
Sbjct: 2964 ATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEIT 3001


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 34/98 (34%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 139  PLFTLRKTGAAPAKAKPAEA-PAAAAPKAEPTAAAVPPPAAPIPTQMPPV---PSPSQPP 194
            P+  + +    PA AKPA A P AA P A   A   PP A    T   PV   P+  +PP
Sbjct: 2289 PVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPP 2348

Query: 195  SG---KPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNR 229
            +    KPV+       P  A+P A K   ++   KM+R
Sbjct: 2349 AAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSR 2386



 Score = 33.5 bits (75), Expect = 0.41
 Identities = 29/98 (29%), Positives = 36/98 (36%), Gaps = 4/98 (4%)

Query: 110  KTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEA--PAAAAPKAE 167
            K +   P+PA  V    +      V    P+     T A P  AKPA    PAAAA K  
Sbjct: 2299 KPAAAKPAPAKPVAAKPVATKMATVR--PPVAVKPATAAKPVAAKPAAVRPPAAAAAKPV 2356

Query: 168  PTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPT 205
             T   VP P A  P    P  +       + V   + T
Sbjct: 2357 ATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEIT 2394


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 34/90 (37%), Positives = 39/90 (43%), Gaps = 20/90 (22%)

Query: 146 TGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPI--------------PTQMPPVPSPS 191
           T  AP +A P  APAAAA  A P   A PPP AP+                  PP P P+
Sbjct: 107 TPPAPPRA-PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA 165

Query: 192 QP----PSGKPVSAVKPT-VAPPLAEPGAG 216
           QP        P++A  P   APP   P AG
Sbjct: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPAG 195



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/75 (36%), Positives = 29/75 (38%), Gaps = 4/75 (5%)

Query: 131 GGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKA----EPTAAAVPPPAAPIPTQMPP 186
           G + +   PL       AAP    P   P  A P A    EP     P P AP   Q PP
Sbjct: 168 GPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPP 227

Query: 187 VPSPSQPPSGKPVSA 201
            P P  PP G  V A
Sbjct: 228 PPQPQPPPEGGAVRA 242



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 35/101 (34%), Positives = 41/101 (40%), Gaps = 11/101 (10%)

Query: 117 SPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAE--APAAAAPKAEPTAAAVP 174
           +P      A   P  G  + G      R   AAP  A P    AP A AP A P  A  P
Sbjct: 148 APRAAAAAATAPPSPGPAQPGP-----RAQRAAPLAAPPPAPAAPPAVAPPAGPRRA--P 200

Query: 175 PPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGA 215
           PPA  +  + PP+P P QPP+        P    P  E GA
Sbjct: 201 PPA--VAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGA 239



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 28/68 (41%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 148 AAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVA 207
           A  A A PA AP AAA  A  TA   P PA P P      P  + PP+     AV P   
Sbjct: 138 APVAAAAPARAPRAAAAAA--TAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAG 195

Query: 208 PPLAEPGA 215
           P  A P A
Sbjct: 196 PRRAPPPA 203



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 29/73 (39%), Positives = 35/73 (47%), Gaps = 8/73 (10%)

Query: 148 AAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVS----AVK 203
           AAPA+A  A A AA AP +   A   P      P   PP P+P+ PP+  P +    A  
Sbjct: 143 AAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPP-PAPAAPPAVAPPAGPRRAPP 201

Query: 204 PTVA---PPLAEP 213
           P VA   PPL  P
Sbjct: 202 PAVAAREPPLPPP 214



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 4/68 (5%)

Query: 150 PAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPP 209
           P +     AP  A   A   AAA  PP  P P   PP P  +  P+  P +A     APP
Sbjct: 102 PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPP-PPAPVAAAAPARAPRAAAAAATAPP 160

Query: 210 L---AEPG 214
               A+PG
Sbjct: 161 SPGPAQPG 168



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 22/63 (34%), Positives = 26/63 (41%), Gaps = 2/63 (3%)

Query: 153 AKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAE 212
           A   + P   A    P  A    PAA      PP P+P  PP+  PV+A  P  AP  A 
Sbjct: 96  AARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPA--PVAAAAPARAPRAAA 153

Query: 213 PGA 215
             A
Sbjct: 154 AAA 156


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 13/75 (17%)

Query: 149 APAKAKPAEAPAAAA---------PKAEP--TAAAVPPPAAPIPTQMPPVPSPSQPPSGK 197
           +P+   P++AP + A         P A P  + +A PPP AP P   PP+  P  PP+  
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745

Query: 198 PV--SAVKPTVAPPL 210
           P+  SA  P   PPL
Sbjct: 746 PMSPSATPPPRVPPL 760



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 32/71 (45%), Positives = 36/71 (50%), Gaps = 6/71 (8%)

Query: 148 AAPAKAKPAEAPAAA--APKAEPTAAAVPPPAAPIPTQMPPVP--SPSQPPSGKPVSAVK 203
           AAP    P   PA+   +P A P   A PP AAP P Q+PP P  SP   PS  P   V 
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQVPPSPPASPPMSPSATPPPRVP 758

Query: 204 PTV-APPLAEP 213
           P + APPL  P
Sbjct: 759 PLLAAPPLQVP 769



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 149 APAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVS---AVKPT 205
           +P  + P +AP +       + +A PP  AP     PP+  P  PP+  P+S      P 
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725

Query: 206 VAPPLAEP 213
             PPLA P
Sbjct: 726 APPPLAAP 733



 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 9/70 (12%)

Query: 149 APAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPP---VPSP------SQPPSGKPV 199
           AP   +   +P    P   P++ A PPP AP     PP   +PSP      + PP   P 
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624

Query: 200 SAVKPTVAPP 209
            A+ P  APP
Sbjct: 625 LALPPLQAPP 634



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 39/115 (33%), Positives = 50/115 (43%), Gaps = 27/115 (23%)

Query: 119 ANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAK--AKPAEAPAAAAPKAEPT-----AA 171
           A G   A   P   K +G   L  LR     P +  A PA  P +++P A P+     A 
Sbjct: 259 ARGTPRAPAHPSQPKPKG---LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315

Query: 172 AVPPP---AAPIPTQMPP-----------VPSPSQPPSGKPV---SAVKPTVAPP 209
            VPPP   A P+P  +PP            PSPS PPS + +    A  P+ APP
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 150 PAKAKPAEA--PAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVA 207
           P +A PA A  P    P    +  A PPP AP    +PP+ +P  PP+  P+S   P   
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS---PLAT 647

Query: 208 PPLAEPGA 215
           P    P A
Sbjct: 648 PSPQAPNA 655



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/120 (25%), Positives = 43/120 (35%), Gaps = 12/120 (10%)

Query: 104 CEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAA 163
           C ++   + +  P P      A   P         PL  L     +P    P +AP   A
Sbjct: 567 CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626

Query: 164 --PKAEPTAAAVPPPAAPIPTQMPPVPS---------PSQPPSGKPVSA-VKPTVAPPLA 211
             P   P +    PP +P+ T  P  P+         P  PP   PV A   P  +PP++
Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 149 APAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPV-PSPSQPPSGKPVSAVKPTVA 207
           +P  + P    A   P+A P  AA P    P P   PP+ PS + PP   P+ A  P   
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768

Query: 208 PP 209
           PP
Sbjct: 769 PP 770



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 3/67 (4%)

Query: 150 PAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVS--AVKPTVA 207
           P  A P + P +       + +A PPP  P     PP+  P  PP+  P+S  A  P  A
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788

Query: 208 PP-LAEP 213
           PP LA P
Sbjct: 789 PPALATP 795



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 7/76 (9%)

Query: 145 KTGAAPAKAKPAEAPAAAAP---KAEPTAAAVPPPAAPIPTQMPPVPSP----SQPPSGK 197
           +T +AP      E P   AP   +A P+    PPP  P     PP  +P    S P  G 
Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL 606

Query: 198 PVSAVKPTVAPPLAEP 213
           P   + P   PP   P
Sbjct: 607 PSPPLSPLATPPPQAP 622



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 5/62 (8%)

Query: 153 AKPAEAPAAAAPKAEPTAAAVPP-PAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLA 211
           A P  +P+A  P   P + A PP    P P   PP+   + PP   P     P  APPL 
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP----PPLAAPPLQ 736

Query: 212 EP 213
            P
Sbjct: 737 VP 738



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 27/69 (39%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 150 PAKAKPAEAP----AAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPT 205
           P +  P+ AP     A+AP   P     PP  AP P Q PP P  + PP      A  P 
Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLET-PPCPAPCPLQAPPSPLTTPPPETPSSIATPPP 592

Query: 206 VAPP-LAEP 213
            APP LA P
Sbjct: 593 QAPPALASP 601



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 14/112 (12%)

Query: 118 PANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAK-AKPAEAPAAAAPKAEPTAAAV--- 173
           P  G+    L P         P   L    A P+  A P  +P A      P A AV   
Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 661

Query: 174 -----PPPAAPI-----PTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGA 215
                PPP+ P+     P   PPV   + PPS  P S   P +  P + P +
Sbjct: 662 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 7/68 (10%)

Query: 153 AKPAEAPAAAAPKAEPTAAAVPP---PAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVA-- 207
           A P  +P+A  P   P   A PP   P +P P  +P  P    PP   P  A  P  A  
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSP-PASLPMSPLAKPPPQAPPALATPPLQALP 801

Query: 208 -PPLAEPG 214
            PP + PG
Sbjct: 802 SPPASFPG 809



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 31/84 (36%), Positives = 37/84 (44%), Gaps = 16/84 (19%)

Query: 138 TPLFTLRKTGAAPAKAKPAEAPAAAA-----------PKAEPTAAAVPPPAAPIPTQMPP 186
           +PL T   +G    KA+P   P  AA           P A P   A P P+AP   Q  P
Sbjct: 302 SPLATPSPSGT---KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP 358

Query: 187 VPSPSQPPSGKPVSAVKPTV-APP 209
            P P+ PPS  P S   P + APP
Sbjct: 359 SP-PATPPSQAPPSMTTPPMQAPP 381



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 28/82 (34%), Positives = 35/82 (42%), Gaps = 9/82 (10%)

Query: 149 APAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQP--PSGKPVSAVKPTV 206
           +P    P +AP A A    P   A+P P A  P Q P  PS S P  P   P     P +
Sbjct: 779 SPLAKPPPQAPPALAT---PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835

Query: 207 APPLAE----PGAGKGLRSEHR 224
           A PL +    P A   L++  R
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRR 857



 Score = 35.8 bits (81), Expect = 0.082
 Identities = 25/70 (35%), Positives = 31/70 (44%), Gaps = 7/70 (10%)

Query: 149 APAKAKPAEAPAAAAPKAEPTAA-----AVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVK 203
           +P  + P    A   P+A P  A     A+P P A  P Q P  PS S P S  P++   
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS--PLATPP 828

Query: 204 PTVAPPLAEP 213
           P   P LA P
Sbjct: 829 PQAPPVLAAP 838



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 30/102 (29%), Positives = 40/102 (39%), Gaps = 12/102 (11%)

Query: 116 PSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAP---KAEPTAAA 172
           PSP+      +  PD       TPL          A   P   P+ +AP   +  P+  A
Sbjct: 307 PSPSGTKARPVPPPDNA----ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362

Query: 173 VPPPAAPIPTQMPPVPSPSQ----PPSGKPVSAVKPTV-APP 209
            PP  AP     PP+ +P      PP   P S   P++ APP
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404



 Score = 33.9 bits (76), Expect = 0.31
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 149 APAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVK--PTV 206
           +P  + P +AP + +     +  A PPP AP     P +  P  PP+   + A +  PT 
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861

Query: 207 APPLAEPG 214
            P  +  G
Sbjct: 862 GPDTSVSG 869



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 9/70 (12%)

Query: 149 APAKAKPAEAPAAAAPKAEPTAAA----VPPPAAPIPT----QMPPVPSPSQPPSGKPVS 200
           +P+ + P    A   P+A P  AA    VPP     PT    + PP P P    SG  ++
Sbjct: 814 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 873

Query: 201 -AVKPTVAPP 209
            A+ P   PP
Sbjct: 874 LALAPGPPPP 883



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 31/108 (28%), Positives = 41/108 (37%), Gaps = 9/108 (8%)

Query: 125 ALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVP---PPAAPIP 181
           AL V       G  PL    + G       P  AP A   ++  T++  P   PPA+   
Sbjct: 43  ALRVLGAAGAVGRKPL--AERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG 100

Query: 182 TQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNR 229
            + PP  + S  P   P  A   T   PL +    KGLR    E + R
Sbjct: 101 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ----KGLRISAEETVAR 144



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 1/60 (1%)

Query: 153 AKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSA-VKPTVAPPLA 211
           A P + P +       +  A PPP AP     PP+ +   PP+  P  A   P+ + P++
Sbjct: 763 APPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 28/78 (35%), Positives = 32/78 (41%), Gaps = 2/78 (2%)

Query: 137 GTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSG 196
           G P   L+   AAP  A    AP  A PK  P   A PP +AP P   P  P+ + P   
Sbjct: 498 GAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQS 557

Query: 197 KPVSAVKPTVAPPLAEPG 214
            P   V    AP L   G
Sbjct: 558 TPTPGV--AAAPTLVSGG 573



 Score = 33.5 bits (75), Expect = 0.41
 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 4/122 (3%)

Query: 129  PDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVP 188
            PDGG ++G       R  G++P  A P E P  + P   P  A        +P + P  P
Sbjct: 1672 PDGG-LKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPP 1730

Query: 189  SP-SQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKEAQNTCAM 247
             P     S +     +P    P   P  G  ++    +K + +R  +   LK  +   A 
Sbjct: 1731 GPIGTERSQRTDRGTEPGPIRPSHRP--GPPVQFGTSDKDSDLRLVVGDSLKAEKELTAS 1788

Query: 248  LT 249
            +T
Sbjct: 1789 VT 1790



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 42/178 (23%), Positives = 59/178 (33%), Gaps = 20/178 (11%)

Query: 144 RKTGAAPAKAKPAEAPAAA--APKAEPTAAAV-------PPPAAP-IPTQMPPVPSPSQP 193
           R + +A  + +P EA      +P +EP            PP   P  P   PP+P P + 
Sbjct: 359 RDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRG 418

Query: 194 PSGK--PVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTF 251
           P+G   P         PP   P           ++    RQR  Q   E           
Sbjct: 419 PAGNWGPPGDYPDRGGPPCKPPAP--------EDEDEAWRQRRKQSSSEISLAVERARRR 470

Query: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEV 309
            E +   +QE R       LK+ + K G     +KA   A    P   A      KE+
Sbjct: 471 REEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKEL 528



 Score = 30.0 bits (66), Expect = 4.5
 Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 1/60 (1%)

Query: 164 PKAEPTAAAVPPPAAPIP-TQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSE 222
           PK+   + A PP + P+P +Q P    P +PP+    + + P+     A+     G   +
Sbjct: 95  PKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGD 154



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 31/118 (26%)

Query: 150 PAKAKPAEAP----AAAAP-----------------KAEPTAAAVPPPAAPIPTQMPPVP 188
           PA+A PA++      AAAP                 +A P    +P    P P +  P  
Sbjct: 549 PAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVP-- 606

Query: 189 SPSQPPSGKPVSAVKPT---VAPPLAEPGAGKGLRSEHREKMNR-MRQRIAQRLKEAQ 242
               PP+  PV  V+P    + P    P  G G     +    R  RQ+  Q LK+ Q
Sbjct: 607 ----PPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQ 660



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 11/82 (13%)

Query: 116  PSPANGVIEALLVPDGGKV--EGGTPLFTLRKTGAAPAKAKPAEAPAAA--APKAEPTAA 171
            PSPA     A     GG+V    G P    R  G  P +  P  +P A   APK  PT  
Sbjct: 1146 PSPA----PARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGP 1201

Query: 172  AVPPPAAPIPTQMPPVPSPSQP 193
             +PP   P+  ++  +P P  P
Sbjct: 1202 -LPPSKEPLKEKL--IPGPLSP 1220


>gi|145386517 phostensin [Homo sapiens]
          Length = 613

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 45/157 (28%), Positives = 66/157 (42%), Gaps = 15/157 (9%)

Query: 83  TEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDG-GKVEG----- 136
           TEG   W+  +    A +    +IE      + P  A  ++E+  V  G G+ E      
Sbjct: 329 TEG---WKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGA 385

Query: 137 -GTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAV-PPPAAPIPTQMPPVPSPSQPP 194
            G PL  L+   + P+   P +A      + E  A  + PPP AP+ +  PP P+  QPP
Sbjct: 386 QGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPL-SPPPPAPTAPQPP 444

Query: 195 SGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMR 231
               +S +   V    A PG G   RS H   +N  R
Sbjct: 445 GDPLMSRLFYGVK---AGPGVGAPRRSGHTFTVNPRR 478


>gi|199559805 phostensin [Homo sapiens]
          Length = 613

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 45/157 (28%), Positives = 66/157 (42%), Gaps = 15/157 (9%)

Query: 83  TEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDG-GKVEG----- 136
           TEG   W+  +    A +    +IE      + P  A  ++E+  V  G G+ E      
Sbjct: 329 TEG---WKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGA 385

Query: 137 -GTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAV-PPPAAPIPTQMPPVPSPSQPP 194
            G PL  L+   + P+   P +A      + E  A  + PPP AP+ +  PP P+  QPP
Sbjct: 386 QGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPL-SPPPPAPTAPQPP 444

Query: 195 SGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMR 231
               +S +   V    A PG G   RS H   +N  R
Sbjct: 445 GDPLMSRLFYGVK---AGPGVGAPRRSGHTFTVNPRR 478


>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
          Length = 904

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 47/143 (32%), Positives = 60/143 (41%), Gaps = 17/143 (11%)

Query: 89  WEKAVGDTVAEDEVVCE---IETDKTSVQVPSPANGVIEALL-VPDGGKVEGGTPLFTLR 144
           WE A G++ A   V        T  TSV V SPA      L   P  GKV         R
Sbjct: 287 WEPAAGNSPARASVPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRP-------R 339

Query: 145 KTGAAP---AKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSA 201
            T ++P   + A P  A AA+ P A P +A  P PA P     P V +P    S    SA
Sbjct: 340 VTNSSPMGWSSAAPCTAAAASHP-AVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSA 398

Query: 202 VKPTVAPPLAEPGAGKGLRSEHR 224
              TV PP   P A +  ++ ++
Sbjct: 399 A--TVDPPAWTPSASRTQQARNK 419



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 28/101 (27%), Positives = 39/101 (38%), Gaps = 5/101 (4%)

Query: 120 NGVIEALLVPDGGKVEGG--TPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPA 177
           N   +   VP G  + G   TP   L K  +        +   +A  +A   A   P PA
Sbjct: 418 NKFFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAPAPGRPSPA 477

Query: 178 -APIPTQMPPVPSPSQPPSGKPVSAVKPTV--APPLAEPGA 215
            A +P+  P   +P   P  KP+ +  P V   P   EP A
Sbjct: 478 TAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPA 518



 Score = 32.3 bits (72), Expect = 0.91
 Identities = 38/123 (30%), Positives = 53/123 (43%), Gaps = 22/123 (17%)

Query: 140 LFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAA--VPPPAAPIPTQMPPV---PSPSQPP 194
           L  L + GA PA  +P+ A  AA P ++P   A    P A P+ +  P V   PS  +PP
Sbjct: 460 LSALEEAGA-PAPGRPSPA-TAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPP 517

Query: 195 ------SGKPVSAVKPTVAPPLAEP------GAGKGLRSE---HREKMNRMRQRIAQRLK 239
                 S    SA+ P     LAE       GAG   + E    + K   + Q ++  L+
Sbjct: 518 APLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQ 577

Query: 240 EAQ 242
           E Q
Sbjct: 578 EGQ 580


>gi|52485606 formin-like 2 [Homo sapiens]
          Length = 1092

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 35/133 (26%), Positives = 52/133 (39%), Gaps = 10/133 (7%)

Query: 90  EKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAA 149
           E+A+      ++ + E+E   T +++    +G I  L V   G +  G+ +      G  
Sbjct: 459 EEAIQRQSTLEKKIHELEKQGT-IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPT 517

Query: 150 PAKAK--------PAEAPAAAAPKAEPTAAAVPP-PAAPIPTQMPPVPSPSQPPSGKPVS 200
              A         P   P++  P+        PP P  P P   PP P P  PP   P  
Sbjct: 518 MGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGP 577

Query: 201 AVKPTVAPPLAEP 213
           A +   APPLA P
Sbjct: 578 AAETVPAPPLAPP 590


>gi|154146199 sal-like 3 [Homo sapiens]
          Length = 1300

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 35/96 (36%), Positives = 44/96 (45%), Gaps = 9/96 (9%)

Query: 134 VEGGTPLFTLRKTG-AAPAK---AKPAEAPAAAAPK----AEPTAAAVPPPAAPIPTQMP 185
           +  G P   +  +G AAPA    A+P   P + A      AEP+A A P  AAP P    
Sbjct: 266 LSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPS-AAPAPAAPA 324

Query: 186 PVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRS 221
           P P+P    S +P SA  P    P +  GA  GL S
Sbjct: 325 PAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPS 360



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 26/66 (39%), Positives = 33/66 (50%), Gaps = 7/66 (10%)

Query: 131 GGKVEGGTPLFTLRKTGAAPAKAKPAEAPA-AAAPKAEPTAAAVPPPAAP--IPTQMPPV 187
           GG  E   P        AAPA A PA APA  +A  ++P +A+ PP  AP  +    P +
Sbjct: 303 GGPAEPSAPA----APSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGL 358

Query: 188 PSPSQP 193
           PSP  P
Sbjct: 359 PSPLLP 364



 Score = 30.0 bits (66), Expect = 4.5
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 6/59 (10%)

Query: 149 APAKAKPAEAPAAA--APKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPT 205
           A  +A+P E  A    A  A  T A  PPPAAP     PP P+   P +   + A+  T
Sbjct: 120 AEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAP----APPTPAYGAPSTNVTLEALLST 174


>gi|239752280 PREDICTED: similar to family with sequence similarity
           48, member B2 [Homo sapiens]
          Length = 779

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 38/115 (33%), Positives = 50/115 (43%), Gaps = 9/115 (7%)

Query: 135 EGGTPL---FTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVP--- 188
           + G+PL   F       A A   PA APAAA   A    AA    AAP  +Q P VP   
Sbjct: 446 QAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIK 505

Query: 189 -SPSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKEAQ 242
            S  +P +G+P   VK  +AP +       GL++ + E   R  Q +    K  Q
Sbjct: 506 ASRRRPAAGRPTRFVK--IAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQ 558


>gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo
           sapiens]
          Length = 288

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/66 (40%), Positives = 32/66 (48%), Gaps = 5/66 (7%)

Query: 150 PAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPP 209
           PA A  A  PAAA P A    AA PP A P       VP+  +PP+  P +A    V P 
Sbjct: 113 PAAAPAAVCPAAADPSAASLCAASPPAAVP-----AAVPAAVRPPAAGPPAAALAAVYPA 167

Query: 210 LAEPGA 215
            A+P A
Sbjct: 168 AADPSA 173



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 29/82 (35%), Positives = 33/82 (40%), Gaps = 16/82 (19%)

Query: 150 PAKAKPAEA------PAAAAPKAEPTAAAVP---PPAAPIPTQMPPVPSPS-------QP 193
           PA A P+ A      P AA P A P A   P   PPAA +    P    PS        P
Sbjct: 122 PAAADPSAASLCAASPPAAVPAAVPAAVRPPAAGPPAAALAAVYPAAADPSAASLCAASP 181

Query: 194 PSGKPVSAVKPTVAPPLAEPGA 215
            +  P +A    VAP    PGA
Sbjct: 182 LAAVPAAASPAAVAPAAVCPGA 203



 Score = 35.8 bits (81), Expect = 0.082
 Identities = 25/90 (27%), Positives = 34/90 (37%), Gaps = 4/90 (4%)

Query: 122 VIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIP 181
           V  A   P    +   +PL  +    +  A A  A  P AA P A    AA  P A P  
Sbjct: 164 VYPAAADPSAASLCAASPLAAVPAAASPAAVAPAAVCPGAAGPSAASLCAASQPAAVPAA 223

Query: 182 TQMPPVPSPSQPPSGKPVSAVKPTVAPPLA 211
                 P+ + P +  P +A +   AP  A
Sbjct: 224 AS----PAAAAPLAVNPAAAARAAAAPAAA 249



 Score = 35.8 bits (81), Expect = 0.082
 Identities = 29/67 (43%), Positives = 34/67 (50%), Gaps = 5/67 (7%)

Query: 150 PAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPV-PSPSQPPS-GKPVS---AVKP 204
           PA    A +PAAAAP A   AAA    AAP    +  V  SP+ P +  +PVS   A  P
Sbjct: 217 PAAVPAAASPAAAAPLAVNPAAAARAAAAPAAACVQSVAESPATPLAIAQPVSFPPAPVP 276

Query: 205 TVAPPLA 211
              PPLA
Sbjct: 277 CAVPPLA 283



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 34/136 (25%), Positives = 46/136 (33%), Gaps = 22/136 (16%)

Query: 92  AVGDTVAEDEVVCEIETDKTSVQV-----PSPANGVIEALLVPDGGKVEGGTPLFTLRKT 146
           A G   A    VC    D ++  +     P+     + A + P       G P   L   
Sbjct: 109 AAGPPAAAPAAVCPAAADPSAASLCAASPPAAVPAAVPAAVRPPAA----GPPAAAL--A 162

Query: 147 GAAPAKAKPAEA-----------PAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPS 195
              PA A P+ A           PAAA+P A   AA  P  A P    +     P+  P+
Sbjct: 163 AVYPAAADPSAASLCAASPLAAVPAAASPAAVAPAAVCPGAAGPSAASLCAASQPAAVPA 222

Query: 196 GKPVSAVKPTVAPPLA 211
               +A  P    P A
Sbjct: 223 AASPAAAAPLAVNPAA 238



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 2/70 (2%)

Query: 148 AAPAKAKPAEA-PAAAAPKAEPTAAAVPPPAAPIPTQMP-PVPSPSQPPSGKPVSAVKPT 205
           A+P  A PA A PAA AP A    AA P  A+      P  VP+ + P +  P++     
Sbjct: 179 ASPLAAVPAAASPAAVAPAAVCPGAAGPSAASLCAASQPAAVPAAASPAAAAPLAVNPAA 238

Query: 206 VAPPLAEPGA 215
            A   A P A
Sbjct: 239 AARAAAAPAA 248



 Score = 33.5 bits (75), Expect = 0.41
 Identities = 21/52 (40%), Positives = 23/52 (44%), Gaps = 5/52 (9%)

Query: 148 AAPAKAKPAEAP-AAAAPKAEPTAAAVPPPAAPI----PTQMPPVPSPSQPP 194
           AAP    PA A  AAAAP A    +    PA P+    P   PP P P   P
Sbjct: 229 AAPLAVNPAAAARAAAAPAAACVQSVAESPATPLAIAQPVSFPPAPVPCAVP 280



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 24/69 (34%), Positives = 27/69 (39%), Gaps = 2/69 (2%)

Query: 148 AAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSP-SQPPSGKPVSAVKPTV 206
           +AP     A   A A   A   AA  PP A P P   P    P +  PS   + A  P  
Sbjct: 81  SAPVVVPSALTRAVAWRPAAAPAAVRPPAAGP-PAAAPAAVCPAAADPSAASLCAASPPA 139

Query: 207 APPLAEPGA 215
           A P A P A
Sbjct: 140 AVPAAVPAA 148



 Score = 30.0 bits (66), Expect = 4.5
 Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 5/64 (7%)

Query: 128 VPDGGKVEGGTPLFTLRKTGAAPAKAKPAEA--PAAAAPKAEPTAAAVPP--PAAPIPTQ 183
           VP         PL  +    AA A A PA A   + A   A P A A P   P AP+P  
Sbjct: 220 VPAAASPAAAAPL-AVNPAAAARAAAAPAAACVQSVAESPATPLAIAQPVSFPPAPVPCA 278

Query: 184 MPPV 187
           +PP+
Sbjct: 279 VPPL 282


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 24/67 (35%), Positives = 29/67 (43%), Gaps = 3/67 (4%)

Query: 149 APAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKP---VSAVKPT 205
           +P   KP  AP  A P   P    +PPP  P+    P  P P  PPS  P    +A  P 
Sbjct: 308 SPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPP 367

Query: 206 VAPPLAE 212
             PP A+
Sbjct: 368 PPPPAAD 374



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 4/74 (5%)

Query: 139 PLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKP 198
           P F      AAP    P   PAA  P   P   + P   AP P   PP P P  PP    
Sbjct: 353 PSFPPHPDFAAPPPPPPP--PAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPF--T 408

Query: 199 VSAVKPTVAPPLAE 212
            +  +P + PPL++
Sbjct: 409 GADGQPAIPPPLSD 422



 Score = 33.5 bits (75), Expect = 0.41
 Identities = 22/64 (34%), Positives = 25/64 (39%), Gaps = 4/64 (6%)

Query: 155 PAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSP--SQPPSGKPVSAVKPTVAPPLAE 212
           P  +P +  P   P  AA PPP  P     P +P P  SQP  G P     P    P   
Sbjct: 348 PPPSPPSFPP--HPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPP 405

Query: 213 PGAG 216
           P  G
Sbjct: 406 PFTG 409



 Score = 33.1 bits (74), Expect = 0.53
 Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 1/69 (1%)

Query: 145 KTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKP 204
           K  +  + + P  AP   +P       A PP   P P  M  +P P  PP G       P
Sbjct: 290 KRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIP-PPPPPVGFGSPGTPP 348

Query: 205 TVAPPLAEP 213
             +PP   P
Sbjct: 349 PPSPPSFPP 357



 Score = 32.7 bits (73), Expect = 0.69
 Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 28/100 (28%)

Query: 144 RKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQM----------------PPV 187
           R +  +P+   PA  P  + P  +P  A  P P  P P  +                PP 
Sbjct: 291 RSSVVSPSHPPPAP-PLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPP 349

Query: 188 PSP----------SQPPSGKPVSAVKPTV-APPLAEPGAG 216
           PSP          + PP   P +A  PT+  PPL++P  G
Sbjct: 350 PSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGG 389



 Score = 32.3 bits (72), Expect = 0.91
 Identities = 28/99 (28%), Positives = 35/99 (35%), Gaps = 4/99 (4%)

Query: 117 SPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPP 176
           SP+    E  L P     E   P+   R +G A  K     +P+   P     +   P P
Sbjct: 257 SPSPSFSEDNLPPP--PAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKP 314

Query: 177 AAPIPTQMPPVPSP--SQPPSGKPVSAVKPTVAPPLAEP 213
               P   PP P P    PP   PV    P   PP + P
Sbjct: 315 GFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPP 353



 Score = 30.0 bits (66), Expect = 4.5
 Identities = 19/58 (32%), Positives = 24/58 (41%), Gaps = 3/58 (5%)

Query: 162 AAPKAEPTAA-AVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKG 218
           A PK     + + PPPA P+ +  PP P P   P   P     P +  P   P  G G
Sbjct: 287 AGPKRSSVVSPSHPPPAPPLGS--PPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFG 342


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,641,347
Number of Sequences: 37866
Number of extensions: 1044389
Number of successful extensions: 25950
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 500
Number of HSP's successfully gapped in prelim test: 1059
Number of HSP's that attempted gapping in prelim test: 11311
Number of HSP's gapped (non-prelim): 9000
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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