Search of human proteins with 19923632

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923632 Kazal-type serine peptidase inhibitor domain 1
precursor [Homo sapiens]
         (304 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precu...   651   0.0  
gi|56090548 insulin-like growth factor binding protein-like 1 [H...   174   9e-44
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa...   173   2e-43
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]            91   1e-18
gi|22129776 HtrA serine peptidase 3 [Homo sapiens]                     73   3e-13
gi|144226847 obscurin-like 1 [Homo sapiens]                            60   2e-09
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ...    57   3e-08
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ...    57   3e-08
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ...    57   3e-08
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ...    57   3e-08
gi|110431348 deleted in colorectal carcinoma [Homo sapiens]            55   6e-08
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ...    55   6e-08
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact...    54   1e-07
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    54   1e-07
gi|54873613 agrin [Homo sapiens]                                       54   2e-07
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]         54   2e-07
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    54   2e-07
gi|157311649 neogenin homolog 1 [Homo sapiens]                         53   4e-07
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    52   5e-07
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    52   5e-07
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo...    52   5e-07
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor...    52   5e-07
gi|109150416 peroxidasin [Homo sapiens]                                52   5e-07
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa...    51   1e-06
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]       50   2e-06
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]        50   2e-06
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]       50   2e-06
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]        50   2e-06
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n...    50   2e-06
gi|126517478 peroxidasin homolog-like [Homo sapiens]                   50   3e-06

>gi|19923632 Kazal-type serine peptidase inhibitor domain 1
           precursor [Homo sapiens]
          Length = 304

 Score =  651 bits (1679), Expect = 0.0
 Identities = 304/304 (100%), Positives = 304/304 (100%)

Query: 1   MLPPPRPAAALALPVLLLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAPCRPEE 60
           MLPPPRPAAALALPVLLLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAPCRPEE
Sbjct: 1   MLPPPRPAAALALPVLLLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAPCRPEE 60

Query: 61  CAAPRGCLAGRVRDACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECRLDTGGDLSRGE 120
           CAAPRGCLAGRVRDACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECRLDTGGDLSRGE
Sbjct: 61  CAAPRGCLAGRVRDACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECRLDTGGDLSRGE 120

Query: 121 VPEPLCACRSQSPLCGSDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYD 180
           VPEPLCACRSQSPLCGSDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYD
Sbjct: 121 VPEPLCACRSQSPLCGSDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYD 180

Query: 181 TWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQI 240
           TWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQI
Sbjct: 181 TWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQI 240

Query: 241 QAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPEEEAESEEN 300
           QAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPEEEAESEEN
Sbjct: 241 QAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPEEEAESEEN 300

Query: 301 DDYY 304
           DDYY
Sbjct: 301 DDYY 304


>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
           sapiens]
          Length = 278

 Score =  174 bits (441), Expect = 9e-44
 Identities = 111/288 (38%), Positives = 136/288 (47%), Gaps = 29/288 (10%)

Query: 7   PAAALALPVLLLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAPCRPEECAAPRG 66
           P  +L LP+LLLLL+ L PP      SP       G  R       C PCRPE C AP  
Sbjct: 2   PRLSLLLPLLLLLLLPLLPPL-----SPSLGIRDVGGRR-----PKCGPCRPEGCPAPAP 51

Query: 67  CLAGRVR--DACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECRLDTGGDLSRGEVPEP 124
           C A  +   D CGCC  C   EG  C         G CG  L C     G    G     
Sbjct: 52  CPAPGISALDECGCCARCLGAEGASC----GGRAGGRCGPGLVCASQAAGAAPEGT---G 104

Query: 125 LCACRSQSPLCGSDGHTYSQICRLQEAARARPDAN---LTVAHPGPCESGPQIVSHPYDT 181
           LC C  +  +CGSDG +Y  +C L+  AR  P A+   L  A  GPCE  P +V  P   
Sbjct: 105 LCVCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSV 164

Query: 182 WNVTGQDVIFGCEVFAYPMASIEWRK-----DGLDI--QLPGDDPHISVQFRGGPQRFEV 234
            NVTG  V   CEV A P   I WRK     +G     +LPGD  +I+VQ RGGP   E 
Sbjct: 165 HNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEA 224

Query: 235 TGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIP 282
           T W+ I  +R  DEG Y+C   N +G+ E+ +++TVL   +  S   P
Sbjct: 225 TAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRSFHFP 272


>gi|4504619 insulin-like growth factor binding protein 7 [Homo
           sapiens]
          Length = 282

 Score =  173 bits (438), Expect = 2e-43
 Identities = 93/242 (38%), Positives = 124/242 (51%), Gaps = 20/242 (8%)

Query: 48  AEGEGCAPCRPEECAA--PRGCLAGRVRDACGCCWECANLEGQLCDLDPSAHFYGHCGEQ 105
           +  + C PC P  C    P GCL G  RDACGCC  CA  EG+ C    +    G+C   
Sbjct: 27  SSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGR--GYCAPG 84

Query: 106 LEC------RLDTGGDLSRGEVPEPLCACRSQSPLCGSDGHTYSQICRLQEA---ARARP 156
           +EC      R    G  + G     +C C+S+ P+CGSDG TY   C+L+ A   A +R 
Sbjct: 85  MECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRG 144

Query: 157 DANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRK---DGLDIQ 213
           +  +T    G CE GP IV+ P D WNVTG  V   CEV   P   + W K       +Q
Sbjct: 145 EKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQ 204

Query: 214 ----LPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLT 269
               LPGD  ++++Q RGGP++ EVTGW+ +  +   D G Y C   N+ GQ  A A +T
Sbjct: 205 RTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKIT 264

Query: 270 VL 271
           V+
Sbjct: 265 VV 266


>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
          Length = 480

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 72/187 (38%), Positives = 86/187 (45%), Gaps = 33/187 (17%)

Query: 7   PAAALALPVLLLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAP-CRPEECAA-P 64
           P AAL LP+LLLLL      P  A+ S      R G    LA G  C   C P  C   P
Sbjct: 4   PRAAL-LPLLLLLLAA----PASAQLS------RAGRSAPLAAG--CPDRCEPARCPPQP 50

Query: 65  RGCLAGRVRDACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECRLDTGGDLS---RGEV 121
             C  GR RDACGCC  C   EG  C L       G CGE L+C +  G   S   R   
Sbjct: 51  EHCEGGRARDACGCCEVCGAPEGAACGLQE-----GPCGEGLQCVVPFGVPASATVRRRA 105

Query: 122 PEPLCACRSQSPLCGSDGHTYSQICRLQEAARA-----RPDANLTVAHPGPCESG---PQ 173
              LC C S  P+CGSD +TY+ +C+L+ A+R      RP   + V   G C  G   P 
Sbjct: 106 QAGLCVCASSEPVCGSDANTYANLCQLRAASRRSERLHRPP--VIVLQRGACGQGQEDPN 163

Query: 174 IVSHPYD 180
            + H Y+
Sbjct: 164 SLRHKYN 170


>gi|22129776 HtrA serine peptidase 3 [Homo sapiens]
          Length = 453

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 59/179 (32%), Positives = 70/179 (39%), Gaps = 43/179 (24%)

Query: 8   AAALALPVLLLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAPCRPEECAAPRGC 67
           A AL L  L  L +   PP   A P P                   A C    C +PR C
Sbjct: 3   ARALLLAALAALALAREPP---AAPCP-------------------ARCDVSRCPSPR-C 39

Query: 68  LAGRVRDACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECRLDTGGDLSRGEVPEPLCA 127
             G V D C CC  CA  EG+ C           CGE LEC         RG     LC 
Sbjct: 40  PGGYVPDLCNCCLVCAASEGEPC----GGPLDSPCGESLEC--------VRG-----LCR 82

Query: 128 CRSQSPLCGSDGHTYSQICRLQEAARARPDANLTVA---HPGPCESGPQIVSHPYDTWN 183
           CR    +CG+DGHTY+ +C LQ A+R     + T       G C  G   +S P   +N
Sbjct: 83  CRWSHAVCGTDGHTYANVCALQAASRRALQLSGTPVRQLQKGACPLGLHQLSSPRYKFN 141


>gi|144226847 obscurin-like 1 [Homo sapiens]
          Length = 1896

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 39/128 (30%), Positives = 54/128 (42%), Gaps = 7/128 (5%)

Query: 148 LQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRK 207
           LQ A R  P        PG  E  P  ++ P   W + G +V+  C     P  ++ W K
Sbjct: 111 LQPAERPLPS-------PGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEK 163

Query: 208 DGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPAS 267
           DG+ +    D  H ++Q          +  L+I A R  D G Y C  RNA G  +A A 
Sbjct: 164 DGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGAL 223

Query: 268 LTVLTPDQ 275
           L V  P +
Sbjct: 224 LQVHQPPE 231



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 32/111 (28%), Positives = 43/111 (38%), Gaps = 9/111 (8%)

Query: 163 AHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHIS 222
           A  G   S P  +  P     V+G +    C V   P   + W K G  +        +S
Sbjct: 3   ASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAA---SERLS 59

Query: 223 VQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
               G      +T      A  P+D G Y C  RNA G+  A A++TVL P
Sbjct: 60  FPADGAEHGLLLT------AALPTDAGVYVCRARNAAGEAYAAAAVTVLEP 104



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 32/98 (32%), Positives = 44/98 (44%), Gaps = 15/98 (15%)

Query: 174  IVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFE 233
            IV  P+D     G    F CE+ +  +A + W KDG  +      P + +Q  G  +   
Sbjct: 1631 IVRGPHDLEVTEGDTATFECEL-SQALADVTWEKDGNALT---PSPRLRLQALGTRRL-- 1684

Query: 234  VTGWLQIQAVRPSDEGTYRCLGRNALGQVEA-PASLTV 270
                LQ++   PSD GTY C    A+G   A P  LTV
Sbjct: 1685 ----LQLRRCGPSDAGTYSC----AVGTARAGPVRLTV 1714



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 40/131 (30%), Positives = 51/131 (38%), Gaps = 17/131 (12%)

Query: 144 QICRLQEAARARPD-ANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMAS 202
           Q+ +  E+  A PD A   V  P  C         P   W   G+   F C V   P   
Sbjct: 225 QVHQPPESPPADPDEAPAPVVEPLKCA--------PKTFWVNEGKHAKFRCYVMGKPEPE 276

Query: 203 IEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQV 262
           IEW  +G  + LP D   +  + R G    +V   L  QA    D G Y C  RN+ GQ 
Sbjct: 277 IEWHWEGRPL-LP-DRRRLMYRDRDGGFVLKV---LYCQA---KDRGLYVCAARNSAGQT 328

Query: 263 EAPASLTVLTP 273
            +   L V  P
Sbjct: 329 LSAVQLHVKEP 339



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 10/71 (14%)

Query: 184 VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
           +T + V+  CEV     A + W KDG +++    +    V    GP R      L + A 
Sbjct: 820 ITSECVMLACEVDRED-APVRWYKDGQEVE----ESDFVVLENEGPHRR-----LVLPAT 869

Query: 244 RPSDEGTYRCL 254
           +PSD G ++C+
Sbjct: 870 QPSDGGEFQCV 880



 Score = 28.9 bits (63), Expect = 5.9
 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 16/106 (15%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
            VT + V+  CE+ +   A + W KDGL++    ++    V  R GP+       L + A 
Sbjct: 1002 VTLECVVLMCEL-SREDAPVRWYKDGLEV----EESEALVLERDGPR-----CRLVLPAA 1051

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNL 289
            +P D G + C      G   A  ++TV  P +      P  RSL+L
Sbjct: 1052 QPEDGGEFVC----DAGDDSAFFTVTVTAPPE--RIVHPAARSLDL 1091



 Score = 28.9 bits (63), Expect = 5.9
 Identities = 34/142 (23%), Positives = 53/142 (37%), Gaps = 34/142 (23%)

Query: 156  PDANLTVAHPGPCESGPQIVS--HPYDTWNVT----------------------GQDVIF 191
            P   LT+ H  P ++G  +    H   T+NV                       G+ V+ 
Sbjct: 1134 PTRTLTLPHAQPEDAGEYVCETRHEAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVL 1193

Query: 192  GCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTY 251
             CE+ +   A + W  +G  +Q  G+   +  +   GP+R      L IQA  P+  G Y
Sbjct: 1194 SCEL-SRAGAPVVWSHNGRPVQ-EGEGLELHAE---GPRRV-----LCIQAAGPAHAGLY 1243

Query: 252  RCLGRNALGQVEAPASLTVLTP 273
             C    A G      ++ V  P
Sbjct: 1244 TCQSGAAPGAPSLSFTVQVAEP 1265


>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
           isoform 4 precursor [Homo sapiens]
          Length = 1505

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 26/139 (18%)

Query: 156 PDANLTVAHPGPC--ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQ 213
           P   L V   G C  E  P+ +  P D   V+G    F C+    P   + W K G  + 
Sbjct: 15  PMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN 74

Query: 214 LPGDDPHISVQFRGGPQRFEVTGW-------LQIQAVR-PSDEGTYRCLGRNALGQVEAP 265
                           QRFE   +       L+IQ +R P DE  Y C+ +N++G++   
Sbjct: 75  ---------------SQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVH 119

Query: 266 ASLTVLTPDQLNSTGIPQL 284
           A LTVL  DQL S G P +
Sbjct: 120 AKLTVLREDQLPS-GFPNI 137



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 193 CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
           C     P   I W KD L +     +  I  Q R G         LQI++   +D+G Y 
Sbjct: 156 CAASGNPDPEITWFKDFLPVDPSASNGRIK-QLRSGA--------LQIESSEETDQGKYE 206

Query: 253 CLGRNALG-QVEAPASLTV 270
           C+  N+ G +  +PA+L V
Sbjct: 207 CVATNSAGVRYSSPANLYV 225



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 15/85 (17%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G +V   C     PM  ++W +   D+  P DD  +      G    E+T          
Sbjct: 250 GGNVNITCVAVGSPMPYVKWMQGAEDLT-PEDDMPV------GRNVLELTD--------V 294

Query: 246 SDEGTYRCLGRNALGQVEAPASLTV 270
            D   Y C+  ++LG +EA A +TV
Sbjct: 295 KDSANYTCVAMSSLGVIEAVAQITV 319


>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
           isoform 2 precursor [Homo sapiens]
          Length = 1910

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 26/139 (18%)

Query: 156 PDANLTVAHPGPC--ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQ 213
           P   L V   G C  E  P+ +  P D   V+G    F C+    P   + W K G  + 
Sbjct: 15  PMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN 74

Query: 214 LPGDDPHISVQFRGGPQRFEVTGW-------LQIQAVR-PSDEGTYRCLGRNALGQVEAP 265
                           QRFE   +       L+IQ +R P DE  Y C+ +N++G++   
Sbjct: 75  ---------------SQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVH 119

Query: 266 ASLTVLTPDQLNSTGIPQL 284
           A LTVL  DQL S G P +
Sbjct: 120 AKLTVLREDQLPS-GFPNI 137



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 193 CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
           C     P   I W KD L +     +  I  Q R G         LQI++   +D+G Y 
Sbjct: 156 CAASGNPDPEITWFKDFLPVDPSASNGRIK-QLRSGA--------LQIESSEETDQGKYE 206

Query: 253 CLGRNALG-QVEAPASLTV 270
           C+  N+ G +  +PA+L V
Sbjct: 207 CVATNSAGVRYSSPANLYV 225



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 15/85 (17%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G +V   C     PM  ++W +   D+  P DD  +      G    E+T          
Sbjct: 246 GGNVNITCVAVGSPMPYVKWMQGAEDLT-PEDDMPV------GRNVLELTD--------V 290

Query: 246 SDEGTYRCLGRNALGQVEAPASLTV 270
            D   Y C+  ++LG +EA A +TV
Sbjct: 291 KDSANYTCVAMSSLGVIEAVAQITV 315


>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
           isoform 3 precursor [Homo sapiens]
          Length = 1501

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 26/139 (18%)

Query: 156 PDANLTVAHPGPC--ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQ 213
           P   L V   G C  E  P+ +  P D   V+G    F C+    P   + W K G  + 
Sbjct: 15  PMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN 74

Query: 214 LPGDDPHISVQFRGGPQRFEVTGW-------LQIQAVR-PSDEGTYRCLGRNALGQVEAP 265
                           QRFE   +       L+IQ +R P DE  Y C+ +N++G++   
Sbjct: 75  ---------------SQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVH 119

Query: 266 ASLTVLTPDQLNSTGIPQL 284
           A LTVL  DQL S G P +
Sbjct: 120 AKLTVLREDQLPS-GFPNI 137



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 193 CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
           C     P   I W KD L +     +  I  Q R G         LQI++   +D+G Y 
Sbjct: 156 CAASGNPDPEITWFKDFLPVDPSASNGRIK-QLRSGA--------LQIESSEETDQGKYE 206

Query: 253 CLGRNALG-QVEAPASLTV 270
           C+  N+ G +  +PA+L V
Sbjct: 207 CVATNSAGVRYSSPANLYV 225



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 15/85 (17%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G +V   C     PM  ++W +   D+  P DD  +      G    E+T          
Sbjct: 246 GGNVNITCVAVGSPMPYVKWMQGAEDLT-PEDDMPV------GRNVLELTD--------V 290

Query: 246 SDEGTYRCLGRNALGQVEAPASLTV 270
            D   Y C+  ++LG +EA A +TV
Sbjct: 291 KDSANYTCVAMSSLGVIEAVAQITV 315


>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
           isoform 1 precursor [Homo sapiens]
          Length = 1948

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 26/139 (18%)

Query: 156 PDANLTVAHPGPC--ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQ 213
           P   L V   G C  E  P+ +  P D   V+G    F C+    P   + W K G  + 
Sbjct: 15  PMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN 74

Query: 214 LPGDDPHISVQFRGGPQRFEVTGW-------LQIQAVR-PSDEGTYRCLGRNALGQVEAP 265
                           QRFE   +       L+IQ +R P DE  Y C+ +N++G++   
Sbjct: 75  ---------------SQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVH 119

Query: 266 ASLTVLTPDQLNSTGIPQL 284
           A LTVL  DQL S G P +
Sbjct: 120 AKLTVLREDQLPS-GFPNI 137



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 193 CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVT---GWLQIQAVRPSDEG 249
           C     P   I W KD L +     +  I  Q R   + FE T   G LQI++   +D+G
Sbjct: 156 CAASGNPDPEITWFKDFLPVDPSASNGRIK-QLRS--ETFESTPIRGALQIESSEETDQG 212

Query: 250 TYRCLGRNALG-QVEAPASLTV 270
            Y C+  N+ G +  +PA+L V
Sbjct: 213 KYECVATNSAGVRYSSPANLYV 234



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 15/85 (17%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G +V   C     PM  ++W +   D+  P DD  +      G    E+T          
Sbjct: 259 GGNVNITCVAVGSPMPYVKWMQGAEDLT-PEDDMPV------GRNVLELTD--------V 303

Query: 246 SDEGTYRCLGRNALGQVEAPASLTV 270
            D   Y C+  ++LG +EA A +TV
Sbjct: 304 KDSANYTCVAMSSLGVIEAVAQITV 328


>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
          Length = 1447

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 39/125 (31%), Positives = 57/125 (45%), Gaps = 18/125 (14%)

Query: 158 ANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGD 217
           A LTV  P      P  ++HP + +     D+ F C V   P+ ++ W K+G D+ +P D
Sbjct: 323 AELTVLVP------PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNG-DVVIPSD 375

Query: 218 DPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLN 277
                 Q  GG         L+I  V  SDEG Y+C+  N  G  +  A L V  P   +
Sbjct: 376 ----YFQIVGGSN-------LRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPS 424

Query: 278 STGIP 282
           S+ +P
Sbjct: 425 SSVLP 429



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 11/73 (15%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDI-QLPGDDPHISVQFRGGPQRFEVTGWLQIQAVR 244
           G  V+  CEV   PM +I W+K+  D+  +PGD   + +           +G LQI  ++
Sbjct: 154 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLP----------SGALQISRLQ 203

Query: 245 PSDEGTYRCLGRN 257
           P D G YRC  RN
Sbjct: 204 PGDIGIYRCSARN 216



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 11/99 (11%)

Query: 175 VSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEV 234
           +  P +   + G+D +  C V  YP  S  W +    IQL            GG      
Sbjct: 243 LQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSK----KYSLLGGSN---- 294

Query: 235 TGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
              L I  V   D G Y C+       + A A LTVL P
Sbjct: 295 ---LLISNVTDDDSGMYTCVVTYKNENISASAELTVLVP 330



 Score = 28.9 bits (63), Expect = 5.9
 Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 16/87 (18%)

Query: 173 QIVSHPYDTWNVTGQDVIFGCEVFA-YPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           + +S P D   + G +V+  C   +   +  I+W+KDG+ + L  D+    +        
Sbjct: 41  RFLSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLS------- 93

Query: 232 FEVTGWLQIQAVRPS-----DEGTYRC 253
               G L IQ +  S     DEG Y+C
Sbjct: 94  ---NGSLLIQNILHSRHHKPDEGLYQC 117


>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
           sapiens]
          Length = 1386

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 50/159 (31%), Positives = 68/159 (42%), Gaps = 20/159 (12%)

Query: 119 GEVPEPLCACRSQSPL-----CGSDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQ 173
           GE+P      RS   L        D  TY+ +       RA    +L+V  P      PQ
Sbjct: 296 GELPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAE-NSVGRAEASGSLSVHVP------PQ 348

Query: 174 IVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFE 233
           +V+ P D     G+ V F CE    P  +I W+K+G  + L    P  S+Q  G   RF 
Sbjct: 349 LVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLL---FPSQSLQPTG---RFS 402

Query: 234 VT--GWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
           V+  G L I AV+  D G Y C   +  G + A A L +
Sbjct: 403 VSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEI 441



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 35/107 (32%), Positives = 48/107 (44%), Gaps = 17/107 (15%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P  +  P +   +    V F CEV   P   + WRK+  D +LP               R
Sbjct: 258 PSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKE--DGELPTG-------------R 302

Query: 232 FEVTG--WLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
           +E+     L I  V   DEGTY C+  N++G+ EA  SL+V  P QL
Sbjct: 303 YEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQL 349



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 39/141 (27%), Positives = 54/141 (38%), Gaps = 5/141 (3%)

Query: 143 SQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMAS 202
           S +  L        D +L  +  GP ++ P+IV  P D     G+     C     P  +
Sbjct: 35  SSLAALNHTLLPPGDPSLNGSRVGPEDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPN 94

Query: 203 IEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQV 262
           IEW K+G  +    +DP            F     +  +  RP DEG Y C+ RN LG  
Sbjct: 95  IEWYKNGARVATVREDPRAHRLLLPSGALF-FPRIVHGRRARP-DEGVYTCVARNYLGAA 152

Query: 263 ---EAPASLTVLTPDQLNSTG 280
               A   + VL  D   S G
Sbjct: 153 ASRNASLEVAVLRDDFRQSPG 173



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 11/90 (12%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P I+  P +   V G  V   C V   P  S+ W+KDG  +Q  GDD    +QF     +
Sbjct: 451 PVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQ--GDD----LQF-----K 499

Query: 232 FEVTGWLQIQAVRPSDEGTYRCLGRNALGQ 261
               G L I  V+  D G Y C+ +++ G+
Sbjct: 500 TMANGTLYIANVQEMDMGFYSCVAKSSTGE 529



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 12/70 (17%)

Query: 198 YPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRN 257
           +P  S+ WRKDG   +L  ++  I++  RGG         L +     SD G Y C+  N
Sbjct: 193 HPEPSVSWRKDGA--RLKEEEGRITI--RGGK--------LMMSHTLKSDAGMYVCVASN 240

Query: 258 ALGQVEAPAS 267
             G+ E+ A+
Sbjct: 241 MAGERESAAA 250


>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
           RhoGEF isoform a [Homo sapiens]
          Length = 6620

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 41/134 (30%), Positives = 54/134 (40%), Gaps = 9/134 (6%)

Query: 139 GHTYSQICRLQEA-ARARPDANLTVAHPGPC-ESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           G +   +CR + A   A     L V     C E  P  +  P       G +  F C V 
Sbjct: 75  GDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVG 134

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGR 256
             P  ++ W KDG  +  P D P + V+  G          L+I+A RP D GTY     
Sbjct: 135 GSPRPAVSWSKDGRRLGEP-DGPRVRVEELGEASA------LRIRAARPRDGGTYEVRAE 187

Query: 257 NALGQVEAPASLTV 270
           N LG   A A+L V
Sbjct: 188 NPLGAASAAAALVV 201



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 35/87 (40%), Positives = 43/87 (49%), Gaps = 12/87 (13%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPH--ISVQFRGGPQRFEVTGWLQIQAV 243
            G  V F C V   PM S+ W KDG   +L  +D H  I+   +GG Q       L I AV
Sbjct: 5140 GYPVSFDCVVTGQPMPSVRWFKDG---KLLEEDDHYMINEDQQGGHQ-------LIITAV 5189

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTV 270
             P+D G YRCL  N++G     A L V
Sbjct: 5190 VPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 12/111 (10%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            G+ V   C V   P   I W KDG  +Q+  D  HI ++   G      +  L + ++  
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQV--DPHHILIEDPDG------SCALILDSLTG 6079

Query: 246  SDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPEEEAE 296
             D G Y C   +A G       + V  P +     + ++R+   V  E+A+
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQVPPRF----VNKVRASPFVEGEDAQ 6126



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 7/90 (7%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
            V G+D  F C +   P   I W KDG  +   G+      + R G         L I+A 
Sbjct: 6120 VEGEDAQFTCTIEGAPYPQIRWYKDGA-LLTTGNKFQTLSEPRSG------LLVLVIRAA 6172

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
               D G Y C   N LG   A A L + +P
Sbjct: 6173 SKEDLGLYECELVNRLGSARASAELRIQSP 6202



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 10/105 (9%)

Query: 172  PQIVSHPYDTWNVTGQDVI-FGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQ 230
            PQ+V    D     G  +  F  +V  YP   + W KDG  +       HI +  +    
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA---HIRMTDK---- 5312

Query: 231  RFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQ 275
              ++   L+I +V   D G Y     NA+G   + A L V  PD+
Sbjct: 5313 --KILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDE 5355



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 25/102 (24%), Positives = 36/102 (35%), Gaps = 15/102 (14%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P+ ++ P       G+D    C++   P   + W KD   +              G   R
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVA------------AGARFR 57

Query: 232 FEVTG---WLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
               G    L I  +   D G Y C  RNA+G+  A   L V
Sbjct: 58  LAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99



 Score = 31.6 bits (70), Expect = 0.91
 Identities = 26/110 (23%), Positives = 44/110 (40%), Gaps = 17/110 (15%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLD---IQLPGDDPHISVQFRGGPQRFEVTGWLQIQA 242
            G  + F  +V   P+ ++ W ++  +   + +  D P  +V              L +  
Sbjct: 5385 GSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHS------LVLLD 5438

Query: 243  VRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPE 292
            V    +GTY C+  NA GQ    ASL V        +G+P++     V E
Sbjct: 5439 VGRQHQGTYTCIASNAAGQALCSASLHV--------SGLPKVEEQEKVKE 5480



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G+     C V   P     W+KDG  +     +    V +    + F     L+I   + 
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVT----EGRRHVVYEDAQENFV----LKILFCKQ 303

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTP 273
           SD G Y C   N +GQ  +   + V  P
Sbjct: 304 SDRGLYTCTASNLVGQTYSSVLVVVREP 331



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 10/61 (16%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            CEV + P A + WRKDG  +QL   D +  +   G       T  L +  V P D G Y 
Sbjct: 2668 CEV-SDPEAHVVWRKDG--VQLGPSDKYDFLHTAG-------TRGLVVHDVSPEDAGLYT 2717

Query: 253  C 253
            C
Sbjct: 2718 C 2718



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 12/88 (13%)

Query: 187  QDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPS 246
            +DV F CEV       ++W   GL +Q    +    V  R G  R      L+++ V P 
Sbjct: 4174 EDVEFSCEVSRAGATGVQWCLQGLPLQ---SNEVTEVAVRDG--RIHT---LRLKGVTPE 4225

Query: 247  DEGTYRCLGRNALGQVEAPASLTVLTPD 274
            D GT        LG   + A LTV  P+
Sbjct: 4226 DAGTVSF----HLGNHASSAQLTVRAPE 4249



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 30/103 (29%), Positives = 41/103 (39%), Gaps = 10/103 (9%)

Query: 169  ESGPQIVSHPY-DTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRG 227
            + GP   SH + DT    G  +   C V +       W KDG+++   G   HI      
Sbjct: 4895 QEGPMF-SHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELT-DGRHHHID----- 4947

Query: 228  GPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
              Q  + T  L I  +  +D G Y C   N  GQV   A + V
Sbjct: 4948 --QLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVV 4988



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 21/86 (24%), Positives = 36/86 (41%), Gaps = 10/86 (11%)

Query: 187  QDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPS 246
            Q V+  C+    P A ++W KD   +  P +   +S++ +           L+I  + P+
Sbjct: 2484 QSVVLSCDFRPAPKA-VQWYKDDTPLS-PSEKFKMSLEGQMAE--------LRILRLMPA 2533

Query: 247  DEGTYRCLGRNALGQVEAPASLTVLT 272
            D G YRC   +A    E       +T
Sbjct: 2534 DAGVYRCQAGSAHSSTEVTVEAREVT 2559


>gi|148833506 obscurin, cytoskeletal calmodulin and
           titin-interacting RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 41/134 (30%), Positives = 54/134 (40%), Gaps = 9/134 (6%)

Query: 139 GHTYSQICRLQEA-ARARPDANLTVAHPGPC-ESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           G +   +CR + A   A     L V     C E  P  +  P       G +  F C V 
Sbjct: 75  GDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVG 134

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGR 256
             P  ++ W KDG  +  P D P + V+  G          L+I+A RP D GTY     
Sbjct: 135 GSPRPAVSWSKDGRRLGEP-DGPRVRVEELGEASA------LRIRAARPRDGGTYEVRAE 187

Query: 257 NALGQVEAPASLTV 270
           N LG   A A+L V
Sbjct: 188 NPLGAASAAAALVV 201



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 35/87 (40%), Positives = 43/87 (49%), Gaps = 12/87 (13%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPH--ISVQFRGGPQRFEVTGWLQIQAV 243
            G  V F C V   PM S+ W KDG   +L  +D H  I+   +GG Q       L I AV
Sbjct: 5140 GYPVSFDCVVTGQPMPSVRWFKDG---KLLEEDDHYMINEDQQGGHQ-------LIITAV 5189

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTV 270
             P+D G YRCL  N++G     A L V
Sbjct: 5190 VPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 35/113 (30%), Positives = 45/113 (39%), Gaps = 13/113 (11%)

Query: 185  TGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVR 244
            TG    F   +   P  S+ W KD + +    D   +S Q  G       T  L ++ V 
Sbjct: 6370 TGGTAQFEAIIEGDPQPSVTWYKDSVQLV---DSTRLSQQQEG------TTYSLVLRHVA 6420

Query: 245  PSDEGTYRCLGRNALGQVEAPASLTVL----TPDQLNSTGIPQLRSLNLVPEE 293
              D G Y CL +N  GQV   A L VL     PD    +   +L S   V EE
Sbjct: 6421 SKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQSHRRKLHSFYEVKEE 6473



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 8/94 (8%)

Query: 169  ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
            +  P  +    D   V GQ V   C+V A P A   W KDG  ++         V     
Sbjct: 7460 DRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSS-----RVLISAT 7514

Query: 229  PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQV 262
             + F++   L I  V   D G Y C   NALG V
Sbjct: 7515 LKNFQL---LTILVVVAEDLGVYTCSVSNALGTV 7545



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 12/111 (10%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            G+ V   C V   P   I W KDG  +Q+  D  HI ++   G      +  L + ++  
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQV--DPHHILIEDPDG------SCALILDSLTG 6079

Query: 246  SDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPEEEAE 296
             D G Y C   +A G       + V  P +     + ++R+   V  E+A+
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQVPPRF----VNKVRASPFVEGEDAQ 6126



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 7/90 (7%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
            V G+D  F C +   P   I W KDG  +   G+      + R G         L I+A 
Sbjct: 6120 VEGEDAQFTCTIEGAPYPQIRWYKDGA-LLTTGNKFQTLSEPRSG------LLVLVIRAA 6172

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
               D G Y C   N LG   A A L + +P
Sbjct: 6173 SKEDLGLYECELVNRLGSARASAELRIQSP 6202



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 10/105 (9%)

Query: 172  PQIVSHPYDTWNVTGQDVI-FGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQ 230
            PQ+V    D     G  +  F  +V  YP   + W KDG  +       HI +  +    
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA---HIRMTDK---- 5312

Query: 231  RFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQ 275
              ++   L+I +V   D G Y     NA+G   + A L V  PD+
Sbjct: 5313 --KILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDE 5355



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 25/102 (24%), Positives = 36/102 (35%), Gaps = 15/102 (14%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P+ ++ P       G+D    C++   P   + W KD   +              G   R
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVA------------AGARFR 57

Query: 232 FEVTG---WLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
               G    L I  +   D G Y C  RNA+G+  A   L V
Sbjct: 58  LAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99



 Score = 31.6 bits (70), Expect = 0.91
 Identities = 26/110 (23%), Positives = 44/110 (40%), Gaps = 17/110 (15%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLD---IQLPGDDPHISVQFRGGPQRFEVTGWLQIQA 242
            G  + F  +V   P+ ++ W ++  +   + +  D P  +V              L +  
Sbjct: 5385 GSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHS------LVLLD 5438

Query: 243  VRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPE 292
            V    +GTY C+  NA GQ    ASL V        +G+P++     V E
Sbjct: 5439 VGRQHQGTYTCIASNAAGQALCSASLHV--------SGLPKVEEQEKVKE 5480



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G+     C V   P     W+KDG  +     +    V +    + F     L+I   + 
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVT----EGRRHVVYEDAQENFV----LKILFCKQ 303

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTP 273
           SD G Y C   N +GQ  +   + V  P
Sbjct: 304 SDRGLYTCTASNLVGQTYSSVLVVVREP 331



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 10/61 (16%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            CEV + P A + WRKDG  +QL   D +  +   G       T  L +  V P D G Y 
Sbjct: 2668 CEV-SDPEAHVVWRKDG--VQLGPSDKYDFLHTAG-------TRGLVVHDVSPEDAGLYT 2717

Query: 253  C 253
            C
Sbjct: 2718 C 2718



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 12/88 (13%)

Query: 187  QDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPS 246
            +DV F CEV       ++W   GL +Q    +    V  R G  R      L+++ V P 
Sbjct: 4174 EDVEFSCEVSRAGATGVQWCLQGLPLQ---SNEVTEVAVRDG--RIHT---LRLKGVTPE 4225

Query: 247  DEGTYRCLGRNALGQVEAPASLTVLTPD 274
            D GT        LG   + A LTV  P+
Sbjct: 4226 DAGTVSF----HLGNHASSAQLTVRAPE 4249



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 30/103 (29%), Positives = 41/103 (39%), Gaps = 10/103 (9%)

Query: 169  ESGPQIVSHPY-DTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRG 227
            + GP   SH + DT    G  +   C V +       W KDG+++   G   HI      
Sbjct: 4895 QEGPMF-SHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELT-DGRHHHID----- 4947

Query: 228  GPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
              Q  + T  L I  +  +D G Y C   N  GQV   A + V
Sbjct: 4948 --QLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVV 4988



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 21/86 (24%), Positives = 36/86 (41%), Gaps = 10/86 (11%)

Query: 187  QDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPS 246
            Q V+  C+    P A ++W KD   +  P +   +S++ +           L+I  + P+
Sbjct: 2484 QSVVLSCDFRPAPKA-VQWYKDDTPLS-PSEKFKMSLEGQMAE--------LRILRLMPA 2533

Query: 247  DEGTYRCLGRNALGQVEAPASLTVLT 272
            D G YRC   +A    E       +T
Sbjct: 2534 DAGVYRCQAGSAHSSTEVTVEAREVT 2559


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 43/142 (30%), Positives = 56/142 (39%), Gaps = 31/142 (21%)

Query: 54  APCRPEECAAPRGCLAGRVRDACGCCWECANLE-----------GQLCDLDPSAHFYGH- 101
           +PC   +CA    C     + AC C   C++L            G  C+L+ +A   G  
Sbjct: 466 SPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGRE 525

Query: 102 --------CGEQLECRLDTGGDLSRGEVPEPLCACRSQ-----SPLCGSDGHTYSQICRL 148
                   C    +CR    G L   E     C C S+      P+CGSDGHTY   C L
Sbjct: 526 IQVARKGPCDRCGQCRF---GALCEAETGR--CVCPSECVALAQPVCGSDGHTYPSECML 580

Query: 149 QEAARARPDANLTVAHPGPCES 170
              A      +L VA  GPCE+
Sbjct: 581 HVHA-CTHQISLHVASAGPCET 601



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 41/136 (30%), Positives = 52/136 (38%), Gaps = 24/136 (17%)

Query: 55  PCRPEECAAPR-GCLAGRVRDACGCCWECANLEGQLCDLDPSAH-----FYGH-CGEQLE 107
           PC  + C   R G L       C C  EC  L   +C  D   +      + H C  Q+ 
Sbjct: 533 PC--DRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQIS 590

Query: 108 CRL------DTGGDL--------SRGEVPEPLCACRSQSPLCGSDGHTYSQICRLQEAAR 153
             +      +T GD         S G+   P C      P+CGSDG TY   C L+EAA 
Sbjct: 591 LHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAA- 649

Query: 154 ARPDANLTVAHPGPCE 169
                 +  A  GPCE
Sbjct: 650 CLQQTQIEEARAGPCE 665



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 38/142 (26%), Positives = 54/142 (38%), Gaps = 20/142 (14%)

Query: 52  GCAPCRPEECAAPR----------GCLAGRVRDACGCCWECANLEGQLCDLDPSAHFYGH 101
           GC PC  +   A R           C  G     CG C +   L    C+ D SA     
Sbjct: 843 GCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAP--AT 900

Query: 102 CGEQ-----LECRLDTGGDLSRGEVPEPLCACRSQSPLCGSDGHTYSQICRLQEAARARP 156
           C E        C  ++G   +    P   C   + + +CGSDG TY   C+L+  A  R 
Sbjct: 901 CAEMRCEFGARCVEESGS--AHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIA-CRQ 957

Query: 157 DANLTVAHPGPCESGPQIVSHP 178
              +++   GPC+      +HP
Sbjct: 958 GLQISIQSLGPCQEAVAPSTHP 979



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 42/146 (28%), Positives = 47/146 (32%), Gaps = 40/146 (27%)

Query: 58  PEECAAPRGCLAGRVRDACGC-----------------------CW----ECANLEG--- 87
           PE C     CL+ R R  C C                       CW    EC        
Sbjct: 396 PEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPS 455

Query: 88  ---QLCDLDPSAHFYGHCGEQLECRLDTGGDLSRGEVPEPLCACRS-QSPLCGSDGHTYS 143
                CD  PS      C     C +  G         E L AC S   P+CGSDG TY 
Sbjct: 456 KHQGPCDQAPSPCLGVQCAFGATCAVKNG-----QAACECLQACSSLYDPVCGSDGVTYG 510

Query: 144 QICRLQEAARARPDANLTVAHPGPCE 169
             C L EA        + VA  GPC+
Sbjct: 511 SACEL-EATACTLGREIQVARKGPCD 535



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 49/174 (28%), Positives = 60/174 (34%), Gaps = 49/174 (28%)

Query: 47  LAEGEGCAPCRPEECAAPRGCLAGRVRDACGC-----------CWECANLEGQLCDLDPS 95
           +A    C  C    CA    C AG+    C C           C       G  C+L  +
Sbjct: 593 VASAGPCETCGDAVCAFGAVCSAGQ----CVCPRCEHPPPGPVCGSDGVTYGSACELREA 648

Query: 96  AHFY---------GHCGEQLECRLDTGGDLSRGEVPEPLC-------------------- 126
           A            G C EQ EC     G    G+  + LC                    
Sbjct: 649 ACLQQTQIEEARAGPC-EQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDF 707

Query: 127 ACRSQ--SPLCGSDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHP 178
           +C+S   SP+CGSDG TYS  C L++ AR      L VA  G C  GP     P
Sbjct: 708 SCQSVPGSPVCGSDGVTYSTECELKK-ARCESQRGLYVAAQGACR-GPTFAPLP 759



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 43/164 (26%), Positives = 61/164 (37%), Gaps = 37/164 (22%)

Query: 44  MRLLAEGEGCA---PCRPEECAAPRGCL--AGRVRDACGCCWECANL-EGQLCDLDPSAH 97
           +RLL+ G  C    PC    C+    C   A  +  +C C   C    EG +C  D  A 
Sbjct: 234 IRLLSRGP-CGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSD-GAD 291

Query: 98  FYGHCG---------EQLECRLDTGGDLSRGEVPEPLCACR------------------- 129
           + G C          E +  + D   D  +G +P+P  +CR                   
Sbjct: 292 YPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPA 351

Query: 130 SQSPLCGSDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQ 173
            Q+P+CG DG TY   C +  +  AR    L     G C+   Q
Sbjct: 352 RQAPVCGDDGVTYENDCVMGRSGAAR-GLLLQKVRSGQCQGRDQ 394



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 7/55 (12%)

Query: 124 PLCACR------SQSPLCGSDGHTYSQICRLQEAARARPDANLTVAHPGPCESGP 172
           P C+C       +  P+C  DG TY   C  Q+ A  R    +   H GPC+  P
Sbjct: 412 PRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQ-AECRQQRAIPSKHQGPCDQAP 465



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 7/51 (13%)

Query: 126 CACRSQ------SPLCGSDGHTYSQICRLQEAARARPDANLTVAHPGPCES 170
           C C+        +P+CGSD  TYS  C LQ  A+      + +   GPC S
Sbjct: 195 CVCKKSPCPSVVAPVCGSDASTYSNECELQR-AQCSQQRRIRLLSRGPCGS 244


>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
          Length = 1215

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 23/160 (14%)

Query: 138 DGHTYSQICR-LQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           D  TY+  CR + E   A  +  L V H       PQ+   P D     G+  +  C   
Sbjct: 642 DAGTYT--CRAVNELGDASAEIQLAVGH------APQLTELPRDVTVELGRSALLACRAT 693

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQF---RGGPQRFEVTGWLQIQAVRPSDEGTYRC 253
             P  ++ WR+        GD   + ++    RG   R   +G L  ++V P D+  Y C
Sbjct: 694 GRPPPTVTWRR--------GDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVC 745

Query: 254 LGRNALGQVEAPASLTVL--TPDQLNSTGIPQLRSLNLVP 291
             RN  G+V+A A L V    P Q+ S+  P +R L   P
Sbjct: 746 EARNVFGKVQAEARLIVTGHAPPQIASSA-PTVRVLEGQP 784



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 12/107 (11%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           PQ+  H        G +V   C    YP   I W ++   +Q   +D  I V        
Sbjct: 491 PQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQ---EDSRIHV-------- 539

Query: 232 FEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNS 278
            +  G L IQ V P D G Y C   N +G  +   +L    P  +++
Sbjct: 540 -DAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSA 585



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 14/91 (15%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G++ +  CE    P   + W + GL++ L  +                 +G L+I A + 
Sbjct: 595 GEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSS--------------SGKLRIPAAQE 640

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
            D GTY C   N LG   A   L V    QL
Sbjct: 641 RDAGTYTCRAVNELGDASAEIQLAVGHAPQL 671



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 23/133 (17%)

Query: 148 LQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVT---GQDVIFGCEVFAYPMASIE 204
           +  A   R  A + V  P P     Q+V  P    NVT   G+  +  C V      ++ 
Sbjct: 382 VSRAGTGRAKAQIVVTDPPP-----QLVPAP----NVTVSPGETAVLSCRVLGEAPYNLT 432

Query: 205 WRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEA 264
           W +D     LP     ++       Q  +++  L+I  + P+D G Y+C+  NA G   A
Sbjct: 433 WVRDWR--VLPASTGRVA-------QLADLS--LEISGIIPTDGGRYQCVASNANGVTRA 481

Query: 265 PASLTVLTPDQLN 277
              L V    Q++
Sbjct: 482 SVWLLVREAPQVS 494



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 22/91 (24%), Positives = 36/91 (39%), Gaps = 11/91 (12%)

Query: 170  SGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGP 229
            +G +  + P       G++V   CE    P   + W KD   +      P I+ ++   P
Sbjct: 955  NGSRNANVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPV------PPITNRYGLLP 1008

Query: 230  QRFEVTGWLQIQAVRPSDEGTYRCLGRNALG 260
                 +G L++  V+  D G Y C   N  G
Sbjct: 1009 -----SGSLRLAQVQVGDSGHYECTASNPAG 1034



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 27/106 (25%), Positives = 39/106 (36%), Gaps = 13/106 (12%)

Query: 177 HPYDTWNVTGQDV--IFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEV 234
           HP  T ++T + V     C     P  +I W K+   +   G  PH +V   G       
Sbjct: 862 HPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRG--PHYNVSKEGT------ 913

Query: 235 TGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTG 280
              L I      D G Y C   N +G       L+V T  +++  G
Sbjct: 914 ---LLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNG 956


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 23/160 (14%)

Query: 138 DGHTYSQICR-LQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           D  TY+  CR + E   A  +  L V H       PQ+   P D     G+  +  C   
Sbjct: 759 DAGTYT--CRAVNELGDASAEIQLAVGH------APQLTELPRDVTVELGRSALLACRAT 810

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQF---RGGPQRFEVTGWLQIQAVRPSDEGTYRC 253
             P  ++ WR+        GD   + ++    RG   R   +G L  ++V P D+  Y C
Sbjct: 811 GRPPPTVTWRR--------GDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVC 862

Query: 254 LGRNALGQVEAPASLTVL--TPDQLNSTGIPQLRSLNLVP 291
             RN  G+V+A A L V    P Q+ S+  P +R L   P
Sbjct: 863 EARNVFGKVQAEARLIVTGHAPPQIASSA-PTVRVLEGQP 901



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 53/178 (29%), Positives = 70/178 (39%), Gaps = 33/178 (18%)

Query: 121  VPEPLCACRSQSPLCGSDGHTYSQICRLQEA-------ARARP----DANLTVAHPGPCE 169
            +P PL    SQ  L    GHT  +I ++Q A         A P    D N T+    P  
Sbjct: 3352 LPLPL----SQRTLLHGSGHTL-RISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPV 3406

Query: 170  SGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGP 229
              P  V    D   V G  V   CE    P+  + W KDG        +P +S     GP
Sbjct: 3407 LEP--VEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDG--------EPLLSQSLEQGP 3456

Query: 230  QRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSL 287
                    LQ++AV   D GTY C+  +  G+      LTV+ P  +  +G P   SL
Sbjct: 3457 S-------LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSL 3507



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 13/116 (11%)

Query: 169  ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
            ++ P +   P     V  ++V+  CE    P  +I W+K+GL++        +S Q   G
Sbjct: 3945 QASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATG-----VSTQVLPG 3999

Query: 229  PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQL 284
                   G L+I    P D G Y C+ +N+ G       L V  P  + + G+P L
Sbjct: 4000 -------GQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIEN-GLPDL 4047



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 11/90 (12%)

Query: 189  VIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDE 248
            ++  C V A P   I W +DG+ +Q   +D H     RG   RF     LQ+QA+  +D 
Sbjct: 3599 LVLECSVEAEPAPKITWHRDGIVLQ---EDAHTQFPERG---RF-----LQLQALSTADS 3647

Query: 249  GTYRCLGRNALGQVEAPASLTVLTPDQLNS 278
            G Y C  RNA G       + + T   + S
Sbjct: 3648 GDYSCTARNAAGSTSVAFRVEIHTVPTIRS 3677



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 13/90 (14%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDD--PHISVQFRGGPQRFEVTGWLQIQAV 243
            GQ+V   CE    P   + W KDG  +   G D  PH+     GG         L ++ +
Sbjct: 3232 GQEVRLDCEADGQPPPDVAWLKDGSPL---GQDMGPHLRFYLDGGS--------LVLKGL 3280

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
            R SD G Y C+  N  G+     ++ VL P
Sbjct: 3281 RASDAGAYTCVAHNPAGEDARLHTVNVLVP 3310



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 24/98 (24%), Positives = 44/98 (44%), Gaps = 11/98 (11%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
            V G  ++  C+V   P  ++ W KD + ++       +S   RGG         LQ+  +
Sbjct: 3137 VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVS---RGGR--------LQLSRL 3185

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGI 281
            +P+  GTY C+  N   +      + VL   ++ S+G+
Sbjct: 3186 QPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGV 3223



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 46/147 (31%), Positives = 60/147 (40%), Gaps = 20/147 (13%)

Query: 138  DGHTYSQICRLQ-EAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
            D   YS  CR + +A  A+ D +L V  P P   G        +   + G DV   C   
Sbjct: 1380 DSGLYS--CRAENQAGTAQRDFHLLVLTP-PSVLGAGAAQ---EVLGLAGADVELQCWTS 1433

Query: 197  AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGR 256
              P   +EW KD   + LPG  PH+ VQ  G  Q   +TG          DEG Y+C+  
Sbjct: 1434 GVPTPQVEWTKDRQPV-LPGG-PHLQVQEDG--QVLRITG------SHVGDEGRYQCVAF 1483

Query: 257  NALGQVEAPASLTVLTPDQL---NSTG 280
            +  GQ      L V  P  +   N TG
Sbjct: 1484 SPAGQQARDFQLRVHAPPTIWGSNETG 1510



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 15/127 (11%)

Query: 148  LQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNV-TGQDVIFGCEVFAYPMASIEWR 206
            L  A R +    L+V  P      P+    P D   V  G   +  CE  A P  ++ W 
Sbjct: 3011 LNAAGRDQKLVQLSVLVPPAFRQAPR---GPQDAVLVRVGDKAVLSCETDALPEPTVTWY 3067

Query: 207  KDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPA 266
            KDG  + L       +   RGG +       L+IQ  + SD+G Y C   N  G+     
Sbjct: 3068 KDGQPLVLA----QRTQALRGGQR-------LEIQEAQVSDKGLYSCKVSNVAGEAVRTF 3116

Query: 267  SLTVLTP 273
            +LTV  P
Sbjct: 3117 TLTVQVP 3123



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 31/102 (30%), Positives = 42/102 (41%), Gaps = 12/102 (11%)

Query: 169  ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
            +S P     P D    +G DV   C+    P  +IEW + G  ++        S + R  
Sbjct: 4306 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRA-------SRRLRTL 4358

Query: 229  PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
            P      G L ++ V   D GTY C+  N LG   A A L V
Sbjct: 4359 PD-----GSLWLENVETGDAGTYDCVAHNLLGSATARAFLVV 4395



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 12/107 (11%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           PQ+  H        G +V   C    YP   I W ++   +Q   +D  I V        
Sbjct: 608 PQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQ---EDSRIHV-------- 656

Query: 232 FEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNS 278
            +  G L IQ V P D G Y C   N +G  +   +L    P  +++
Sbjct: 657 -DAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSA 702



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 44/144 (30%), Positives = 56/144 (38%), Gaps = 26/144 (18%)

Query: 134  LCGSDGHTYSQICRLQEAARARPDANLTVAHPGPC-ESGPQIVSHPYDTWNVT-GQDVIF 191
            L  +D   YS  C  + AA +   A     H  P   SGP  V       NV+  Q  + 
Sbjct: 3642 LSTADSGDYS--CTARNAAGSTSVAFRVEIHTVPTIRSGPPAV-------NVSVNQTALL 3692

Query: 192  GCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVT--GWLQIQAVRPSDEG 249
             C+    P   + WRKD + +     DP           RFE+   G L+IQ V   D G
Sbjct: 3693 PCQADGVPAPLVSWRKDRVPL-----DPR--------SPRFEILPEGSLRIQPVLAQDAG 3739

Query: 250  TYRCLGRNALGQVEAPASLTVLTP 273
             Y CL  N+ G       L VL P
Sbjct: 3740 HYLCLASNSAGSDRQGRDLRVLEP 3763



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 30/88 (34%), Positives = 35/88 (39%), Gaps = 11/88 (12%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            CE    P  +I W KDG    LP       V  RGG Q       LQ+   + SD G Y 
Sbjct: 1524 CEARGVPTPNITWFKDGA--LLPTSTK--VVYTRGGRQ-------LQLGRAQSSDAGVYT 1572

Query: 253  CLGRNALGQVEAPASLTVLTPDQLNSTG 280
            C   NA+G  E    L V  P  +   G
Sbjct: 1573 CKASNAVGAAEKATRLDVYVPPTIEGAG 1600



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 11/103 (10%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            CE +A P  +I W KDG  +      P   +Q  G  +       LQIQ  + SD G Y 
Sbjct: 2661 CESWAVPPPTIRWYKDGQPVT-----PSSRLQVLGEGRL------LQIQPTQVSDSGRYL 2709

Query: 253  CLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPEEEA 295
            C+  N  G+ +   ++ +  P      G        L  EEEA
Sbjct: 2710 CVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEA 2752



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 10/97 (10%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
            V G++    C     P   + WRK      L G  P ++V   G          L + +V
Sbjct: 1219 VAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQ-PGVAVLEEGS---------LFLASV 1268

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTG 280
             P+D G Y C   N +G     A L V  P  +   G
Sbjct: 1269 SPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDG 1305



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 4/104 (3%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLP----GDDPHISVQFRGGPQRFEVTGWLQ 239
            + GQ +   C+   +P+  I W KD   + +P    G    +     GG +  +    L 
Sbjct: 1313 MAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLH 1372

Query: 240  IQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQ 283
               ++  D G Y C   N  G  +    L VLTP  +   G  Q
Sbjct: 1373 FPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQ 1416



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 17/100 (17%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            CE  A+P  +I W KDG   +        ++Q   G      T  LQI   +  D G Y 
Sbjct: 2563 CEALAFPSPNITWMKDGAPFEASR-----NIQLLPG------THGLQILNAQKEDAGQYT 2611

Query: 253  CLGRNALGQVEAPASLTVLTP------DQLNSTGIPQLRS 286
            C+  N LG+      + VL P      D L   G+ ++++
Sbjct: 2612 CVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKT 2651



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 17/102 (16%)

Query: 172  PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
            PQ+   P     + G+ +   C     P   + W KDG+ +Q  G  P  SV F      
Sbjct: 1120 PQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQ--GRGPQGSVHFA----- 1172

Query: 232  FEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
                      A+R SD G YRC   N+ G       L VL P
Sbjct: 1173 ----------AIRTSDAGRYRCEASNSAGVDAWEVELRVLEP 1204



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 13/110 (11%)

Query: 180  DTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQ 239
            D     G      C+    P  +I W KDG  +   G +   ++Q          +G L 
Sbjct: 4046 DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVS--GAEGKFTIQ---------PSGELL 4094

Query: 240  IQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNL 289
            ++ +   D GTY C   NA+G+      LT+L       T +P  RSL L
Sbjct: 4095 VKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVF--TTLPGDRSLRL 4142



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 15/92 (16%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGW--LQIQ 241
            +    V   C+V A+P   + W KD   + L             G + F + G   LQ+ 
Sbjct: 2950 ILNSSVSLPCDVHAHPNPEVTWYKDSQALSL-------------GEEVFLLPGTHTLQLG 2996

Query: 242  AVRPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
              R SD G Y C   NA G+ +    L+VL P
Sbjct: 2997 RARLSDSGMYTCEALNAAGRDQKLVQLSVLVP 3028



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 28/92 (30%), Positives = 34/92 (36%), Gaps = 11/92 (11%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTG-WLQIQAVR 244
            G      CE    P   I WRKDG    LPG+          G Q     G  L +   +
Sbjct: 2177 GHPTSLSCECRGVPFPKISWRKDGQ--PLPGEG--------AGLQHVSAVGRLLYLGQAQ 2226

Query: 245  PSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
             + EGTY C   N +G       L V  P Q+
Sbjct: 2227 LAQEGTYTCECSNVVGNSSQDLQLEVHVPPQI 2258



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 14/91 (15%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G++ +  CE    P   + W + GL++ L  +                 +G L+I A + 
Sbjct: 712 GEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSS--------------SGKLRIPAAQE 757

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
            D GTY C   N LG   A   L V    QL
Sbjct: 758 RDAGTYTCRAVNELGDASAEIQLAVGHAPQL 788



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 35/150 (23%), Positives = 58/150 (38%), Gaps = 23/150 (15%)

Query: 140  HTYSQICRLQE-AARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTG---QDVIFGCEV 195
            HT    C  +  A RA     L+V  P      P+++       N+T      +   CE 
Sbjct: 2323 HTGRYSCVAENLAGRAERKFELSVLVP------PELIGDLDPLTNITAALHSPLTLLCEA 2376

Query: 196  FAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGW-LQIQAVRPSDEGTYRCL 254
               P  +I W + G +   PG+D ++              GW L++   +  D G Y CL
Sbjct: 2377 MGIPPPAIRWFR-GEEPVSPGEDTYLLAG-----------GWMLKMTQTQEQDSGLYSCL 2424

Query: 255  GRNALGQVEAPASLTVLTPDQLNSTGIPQL 284
              N  G+     S+ VL P  + +  + ++
Sbjct: 2425 ASNEAGEARRNFSVEVLVPPSIENEDLEEV 2454



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 32/141 (22%), Positives = 50/141 (35%), Gaps = 17/141 (12%)

Query: 137  SDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
            SD   Y+  C+   A  A   A     +  P   G      PY    V G+ V   C   
Sbjct: 1566 SDAGVYT--CKASNAVGAAEKATRLDVYVPPTIEGAG--GRPYVVKAVAGRPVALECVAR 1621

Query: 197  AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTG-WLQIQAVRPSDEGTYRCLG 255
             +P  ++ W  +GL +                  R E  G  L++++   +  G Y C+ 
Sbjct: 1622 GHPSPTLSWHHEGLPVA------------ESNESRLETDGSVLRLESPGEASSGLYSCVA 1669

Query: 256  RNALGQVEAPASLTVLTPDQL 276
             +  G+     S+ V  P QL
Sbjct: 1670 SSPAGEAVLQYSVEVQVPPQL 1690



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 33/139 (23%), Positives = 49/139 (35%), Gaps = 23/139 (16%)

Query: 138  DGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFA 197
            D  TYS +  + EA  AR    LTV  P   E   Q    P +     G  +   C+   
Sbjct: 3467 DSGTYSCVA-VSEAGEARRHFQLTVMEPPHIEDSGQ----PTELSLTPGAPMELLCDAQG 3521

Query: 198  YPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRN 257
             P  +I W KDG  +    ++   +                  + +R  D G Y CL  +
Sbjct: 3522 TPQPNITWHKDGQALTRLENNSRAT------------------RVLRVRDAGLYTCLAES 3563

Query: 258  ALGQVEAPASLTVLTPDQL 276
              G +E    + V  P  +
Sbjct: 3564 PAGAIEKSFRVRVQAPPNI 3582



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 19/110 (17%)

Query: 167  PCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFR 226
            P   GP +V+ P          V   C     P  ++ W KDG  +  P   P + V F 
Sbjct: 1983 PSLPGPVLVNTP----------VRLTCNATGAPSPTLMWLKDGNPVS-PAGTPGLQV-FP 2030

Query: 227  GGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
            GG         L + + R SD G Y C+  +A+G+      L V  P  +
Sbjct: 2031 GGRV-------LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSI 2073



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 26/86 (30%), Positives = 34/86 (39%), Gaps = 11/86 (12%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            GQ     C V  +P   + W KDG  +   GD  HIS               LQ+     
Sbjct: 2460 GQTAHLMCNVTGHPQPKLTWFKDGRPLAR-GDAHHISPD----------GVLLQVLQANL 2508

Query: 246  SDEGTYRCLGRNALGQVEAPASLTVL 271
            S  G Y C+  NA+G+      L+VL
Sbjct: 2509 SSAGHYSCIAANAVGEKTKHFQLSVL 2534



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 11/84 (13%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            C     P  ++ W +DG  +   G +  + +Q +G          L ++  + +  G Y 
Sbjct: 2280 CNATGKPPPTVTWERDGQPV---GAELGLQLQNQGQS--------LHVERAQAAHTGRYS 2328

Query: 253  CLGRNALGQVEAPASLTVLTPDQL 276
            C+  N  G+ E    L+VL P +L
Sbjct: 2329 CVAENLAGRAERKFELSVLVPPEL 2352



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 12/75 (16%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            G  +   C V   P+  I W KDGL ++      H+  Q + G         L I     
Sbjct: 4233 GGSIQLDCVVRGDPVPDIHWIKDGLPLR----GSHLRHQLQNGS--------LTIHRTER 4280

Query: 246  SDEGTYRCLGRNALG 260
             D G Y+CL  N +G
Sbjct: 4281 DDAGRYQCLAENEMG 4295



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 23/133 (17%)

Query: 148 LQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVT---GQDVIFGCEVFAYPMASIE 204
           +  A   R  A + V  P P     Q+V  P    NVT   G+  +  C V      ++ 
Sbjct: 499 VSRAGTGRAKAQIVVTDPPP-----QLVPAP----NVTVSPGETAVLSCRVLGEAPYNLT 549

Query: 205 WRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEA 264
           W +D     LP     ++       Q  +++  L+I  + P+D G Y+C+  NA G   A
Sbjct: 550 WVRDWR--VLPASTGRVA-------QLADLS--LEISGIIPTDGGRYQCVASNANGVTRA 598

Query: 265 PASLTVLTPDQLN 277
              L V    Q++
Sbjct: 599 SVWLLVREAPQVS 611



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 36/149 (24%), Positives = 46/149 (30%), Gaps = 36/149 (24%)

Query: 147  RLQEAA-RARPDANLTVAHPGPCESG------------------------PQIVSHPYDT 181
            RLQ+ A R  P   L +  PGP +S                         P I     D 
Sbjct: 3807 RLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDF 3866

Query: 182  WNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQ 241
                   V+  C     P  ++ W K G  +             RG   R   +G L+I 
Sbjct: 3867 TVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGA-----------RGSGYRVSPSGALEIG 3915

Query: 242  AVRPSDEGTYRCLGRNALGQVEAPASLTV 270
               P   G Y C  RN+ G       LTV
Sbjct: 3916 QALPIHAGRYTCSARNSAGVAHKHVFLTV 3944



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 34/134 (25%), Positives = 46/134 (34%), Gaps = 18/134 (13%)

Query: 137  SDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
            SD   YS +  +      R D  L V  P      P I+    +   V  + V   C+  
Sbjct: 2043 SDSGRYSCVA-VSAVGEDRQDVVLQVHMP------PSILGEELNVSVVANESVALECQSH 2095

Query: 197  AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGR 256
            A P   + W KDG  ++ P    H+S               LQ+      D G Y C   
Sbjct: 2096 AMPPPVLSWWKDGRPLE-PRPGVHLSAD----------KALLQVDRADVWDAGHYTCEAL 2144

Query: 257  NALGQVEAPASLTV 270
            N  G  E   +L V
Sbjct: 2145 NQAGHSEKHYNLNV 2158



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 21/95 (22%), Positives = 37/95 (38%), Gaps = 11/95 (11%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            C     P+ +I W ++GL        P + V   G          LQ+     +D  +Y 
Sbjct: 2867 CPALGNPVPTISWLQNGLPFS---PSPRLQVLEDGQV--------LQVSTAEVADAASYM 2915

Query: 253  CLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSL 287
            C+  N  G  E   +L V  P ++    + Q+ ++
Sbjct: 2916 CVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAI 2950



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 34/151 (22%), Positives = 52/151 (34%), Gaps = 19/151 (12%)

Query: 124  PLCACRSQSPLCGSDGHTYSQICRLQEAARA-RPDANLTVAHPGPCESGPQIVSHPYDTW 182
            P  + R Q  L    GH    +C    +A + R   +L V  P      P I   P +  
Sbjct: 3724 PEGSLRIQPVLAQDAGH---YLCLASNSAGSDRQGRDLRVLEP------PAIAPSPSNLT 3774

Query: 183  NVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQA 242
                   +  CE    P   + W KDG  +           + + G  R   +  L + A
Sbjct: 3775 LTAHTPALLPCEASGSPKPLVVWWKDGQKLDF---------RLQQGAYRLLPSNALLLTA 3825

Query: 243  VRPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
              P D   + C+  N +G+      +TV  P
Sbjct: 3826 PGPQDSAQFECVVSNEVGEAHRLYQVTVHVP 3856



 Score = 32.7 bits (73), Expect = 0.41
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 227  GGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
            G P  + +   LQI+ V   DEG Y C   N  G+ +   +L VL P  +
Sbjct: 1839 GIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNI 1888



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 14/39 (35%), Positives = 21/39 (53%)

Query: 238  LQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
            L+I+  + SD G+YRC+  N  G  E    L V  P ++
Sbjct: 1941 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRI 1979



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 11/81 (13%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            C+  A P   + W ++   +   GD+  +    +GG         LQI  VR  + G Y 
Sbjct: 2772 CDTNAIPPPDLTWYREDQPLSA-GDEVSV---LQGGRV-------LQIPLVRAENAGRYS 2820

Query: 253  CLGRNALGQVEAPASLTVLTP 273
            C   N +G+      L VLTP
Sbjct: 2821 CKASNEVGEDWLHYELLVLTP 2841



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 17/94 (18%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTG---WLQIQA 242
            G+ V   C V   P   + W KDGL + L               QR  + G    L+I  
Sbjct: 3328 GELVTMVCPVRGSPPIHVSWLKDGLPLPL--------------SQRTLLHGSGHTLRISK 3373

Query: 243  VRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
            V+ +D G + C+  +  G  +   +L V  P  L
Sbjct: 3374 VQLADAGIFTCVAASPAGVADRNFTLQVQVPPVL 3407


>gi|157311649 neogenin homolog 1 [Homo sapiens]
          Length = 1461

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 29/103 (28%), Positives = 51/103 (49%), Gaps = 12/103 (11%)

Query: 169 ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
           ++ P+ +  P + +     D++F CEV   P  +++W K+G D+ +P D   I  +    
Sbjct: 338 QAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNG-DMVIPSDYFKIVKEHN-- 394

Query: 229 PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVL 271
                    LQ+  +  SDEG Y+C+  N +G  +A A L +L
Sbjct: 395 ---------LQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIIL 428



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 38/131 (29%), Positives = 54/131 (41%), Gaps = 18/131 (13%)

Query: 172 PQIVS------HPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQF 225
           P+++S       P     V GQDV+  C     P  +I+W K+  +  L  +     V  
Sbjct: 243 PEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKN--EEALDTESSERLVLL 300

Query: 226 RGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL--NSTGIPQ 283
            GG         L+I  V   D GTY C+  N    +EA A LTV    +     T I  
Sbjct: 301 AGGS--------LEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYA 352

Query: 284 LRSLNLVPEEE 294
             S+++V E E
Sbjct: 353 HESMDIVFECE 363



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 18/41 (43%), Positives = 23/41 (56%)

Query: 178 PYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDD 218
           P DT +V G  VI  C  ++ P   IEW+KDG  + L  DD
Sbjct: 59  PVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDD 99



 Score = 28.9 bits (63), Expect = 5.9
 Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 12/83 (14%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P+  S P  +    G + I  CEV A  +  + W ++   + L  DD  I +        
Sbjct: 152 PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLL--DDRVIKLP------- 202

Query: 232 FEVTGWLQIQAVRPSDEGTYRCL 254
              +G L I      D G YRC+
Sbjct: 203 ---SGMLVISNATEGDGGLYRCV 222


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 53/178 (29%), Positives = 70/178 (39%), Gaps = 33/178 (18%)

Query: 121  VPEPLCACRSQSPLCGSDGHTYSQICRLQEA-------ARARP----DANLTVAHPGPCE 169
            +P PL    SQ  L    GHT  +I ++Q A         A P    D N T+    P  
Sbjct: 2161 LPLPL----SQRTLLHGSGHTL-RISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPV 2215

Query: 170  SGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGP 229
              P  V    D   V G  V   CE    P+  + W KDG        +P +S     GP
Sbjct: 2216 LEP--VEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDG--------EPLLSQSLEQGP 2265

Query: 230  QRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSL 287
                    LQ++AV   D GTY C+  +  G+      LTV+ P  +  +G P   SL
Sbjct: 2266 S-------LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSL 2316



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 13/116 (11%)

Query: 169  ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
            ++ P +   P     V  ++V+  CE    P  +I W+K+GL++        +S Q   G
Sbjct: 2754 QASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATG-----VSTQVLPG 2808

Query: 229  PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQL 284
                   G L+I    P D G Y C+ +N+ G       L V  P  + + G+P L
Sbjct: 2809 -------GQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIEN-GLPDL 2856



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 11/90 (12%)

Query: 189  VIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDE 248
            ++  C V A P   I W +DG+ +Q   +D H     RG   RF     LQ+QA+  +D 
Sbjct: 2408 LVLECSVEAEPAPKITWHRDGIVLQ---EDAHTQFPERG---RF-----LQLQALSTADS 2456

Query: 249  GTYRCLGRNALGQVEAPASLTVLTPDQLNS 278
            G Y C  RNA G       + + T   + S
Sbjct: 2457 GDYSCTARNAAGSTSVAFRVEIHTVPTIRS 2486



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 13/90 (14%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDD--PHISVQFRGGPQRFEVTGWLQIQAV 243
            GQ+V   CE    P   + W KDG  +   G D  PH+     GG         L ++ +
Sbjct: 2041 GQEVRLDCEADGQPPPDVAWLKDGSPL---GQDMGPHLRFYLDGGS--------LVLKGL 2089

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
            R SD G Y C+  N  G+     ++ VL P
Sbjct: 2090 RASDAGAYTCVAHNPAGEDARLHTVNVLVP 2119



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 24/98 (24%), Positives = 44/98 (44%), Gaps = 11/98 (11%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
            V G  ++  C+V   P  ++ W KD + ++       +S   RGG         LQ+  +
Sbjct: 1946 VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVS---RGGR--------LQLSRL 1994

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGI 281
            +P+  GTY C+  N   +      + VL   ++ S+G+
Sbjct: 1995 QPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGV 2032



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 15/127 (11%)

Query: 148  LQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNV-TGQDVIFGCEVFAYPMASIEWR 206
            L  A R +    L+V  P      P+    P D   V  G   +  CE  A P  ++ W 
Sbjct: 1820 LNAAGRDQKLVQLSVLVPPAFRQAPR---GPQDAVLVRVGDKAVLSCETDALPEPTVTWY 1876

Query: 207  KDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPA 266
            KDG  + L       +   RGG +       L+IQ  + SD+G Y C   N  G+     
Sbjct: 1877 KDGQPLVLA----QRTQALRGGQR-------LEIQEAQVSDKGLYSCKVSNVAGEAVRTF 1925

Query: 267  SLTVLTP 273
            +LTV  P
Sbjct: 1926 TLTVQVP 1932



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 31/102 (30%), Positives = 42/102 (41%), Gaps = 12/102 (11%)

Query: 169  ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
            +S P     P D    +G DV   C+    P  +IEW + G  ++        S + R  
Sbjct: 3115 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRA-------SRRLRTL 3167

Query: 229  PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
            P      G L ++ V   D GTY C+  N LG   A A L V
Sbjct: 3168 PD-----GSLWLENVETGDAGTYDCVAHNLLGSATARAFLVV 3204



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 44/144 (30%), Positives = 56/144 (38%), Gaps = 26/144 (18%)

Query: 134  LCGSDGHTYSQICRLQEAARARPDANLTVAHPGPC-ESGPQIVSHPYDTWNVT-GQDVIF 191
            L  +D   YS  C  + AA +   A     H  P   SGP  V       NV+  Q  + 
Sbjct: 2451 LSTADSGDYS--CTARNAAGSTSVAFRVEIHTVPTIRSGPPAV-------NVSVNQTALL 2501

Query: 192  GCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVT--GWLQIQAVRPSDEG 249
             C+    P   + WRKD + +     DP           RFE+   G L+IQ V   D G
Sbjct: 2502 PCQADGVPAPLVSWRKDRVPL-----DPR--------SPRFEILPEGSLRIQPVLAQDAG 2548

Query: 250  TYRCLGRNALGQVEAPASLTVLTP 273
             Y CL  N+ G       L VL P
Sbjct: 2549 HYLCLASNSAGSDRQGRDLRVLEP 2572



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 33/100 (33%), Positives = 42/100 (42%), Gaps = 13/100 (13%)

Query: 184 VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
           + G DV   C     P   +EW KD   + LPG  PH+ VQ  G  Q   +TG       
Sbjct: 230 LAGADVELQCWTSGVPTPQVEWTKDRQPV-LPGG-PHLQVQEDG--QVLRITG------S 279

Query: 244 RPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL---NSTG 280
              DEG Y+C+  +  GQ      L V  P  +   N TG
Sbjct: 280 HVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETG 319



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 30/88 (34%), Positives = 35/88 (39%), Gaps = 11/88 (12%)

Query: 193 CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
           CE    P  +I W KDG    LP       V  RGG Q       LQ+   + SD G Y 
Sbjct: 333 CEARGVPTPNITWFKDGA--LLPTSTK--VVYTRGGRQ-------LQLGRAQSSDAGVYT 381

Query: 253 CLGRNALGQVEAPASLTVLTPDQLNSTG 280
           C   NA+G  E    L V  P  +   G
Sbjct: 382 CKASNAVGAAEKATRLDVYVPPTIEGAG 409



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 11/103 (10%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            CE +A P  +I W KDG  +      P   +Q  G  +       LQIQ  + SD G Y 
Sbjct: 1470 CESWAVPPPTIRWYKDGQPVT-----PSSRLQVLGEGRL------LQIQPTQVSDSGRYL 1518

Query: 253  CLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPEEEA 295
            C+  N  G+ +   ++ +  P      G        L  EEEA
Sbjct: 1519 CVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEA 1561



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 17/100 (17%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            CE  A+P  +I W KDG   +        ++Q   G      T  LQI   +  D G Y 
Sbjct: 1372 CEALAFPSPNITWMKDGAPFEASR-----NIQLLPG------THGLQILNAQKEDAGQYT 1420

Query: 253  CLGRNALGQVEAPASLTVLTP------DQLNSTGIPQLRS 286
            C+  N LG+      + VL P      D L   G+ ++++
Sbjct: 1421 CVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKT 1460



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 13/110 (11%)

Query: 180  DTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQ 239
            D     G      C+    P  +I W KDG  +   G +   ++Q          +G L 
Sbjct: 2855 DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVS--GAEGKFTIQ---------PSGELL 2903

Query: 240  IQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNL 289
            ++ +   D GTY C   NA+G+      LT+L       T +P  RSL L
Sbjct: 2904 VKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVF--TTLPGDRSLRL 2951



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 25/89 (28%), Positives = 33/89 (37%), Gaps = 10/89 (11%)

Query: 192 GCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTY 251
           GC     P   + WRK      L G  P ++V   G          L + +V P+D G Y
Sbjct: 23  GCGTHGTPKPQVTWRKGPSSEPLHGQ-PGVAVLEEGS---------LFLASVSPADSGDY 72

Query: 252 RCLGRNALGQVEAPASLTVLTPDQLNSTG 280
            C   N +G     A L V  P  +   G
Sbjct: 73  ECQATNEVGSTSRRAKLVVYVPPSIREDG 101



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 15/92 (16%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGW--LQIQ 241
            +    V   C+V A+P   + W KD   + L             G + F + G   LQ+ 
Sbjct: 1759 ILNSSVSLPCDVHAHPNPEVTWYKDSQALSL-------------GEEVFLLPGTHTLQLG 1805

Query: 242  AVRPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
              R SD G Y C   NA G+ +    L+VL P
Sbjct: 1806 RARLSDSGMYTCEALNAAGRDQKLVQLSVLVP 1837



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 28/92 (30%), Positives = 34/92 (36%), Gaps = 11/92 (11%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTG-WLQIQAVR 244
            G      CE    P   I WRKDG    LPG+          G Q     G  L +   +
Sbjct: 986  GHPTSLSCECRGVPFPKISWRKDGQ--PLPGEG--------AGLQHVSAVGRLLYLGQAQ 1035

Query: 245  PSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
             + EGTY C   N +G       L V  P Q+
Sbjct: 1036 LAQEGTYTCECSNVVGNSSQDLQLEVHVPPQI 1067



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 35/150 (23%), Positives = 58/150 (38%), Gaps = 23/150 (15%)

Query: 140  HTYSQICRLQE-AARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTG---QDVIFGCEV 195
            HT    C  +  A RA     L+V  P      P+++       N+T      +   CE 
Sbjct: 1132 HTGRYSCVAENLAGRAERKFELSVLVP------PELIGDLDPLTNITAALHSPLTLLCEA 1185

Query: 196  FAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGW-LQIQAVRPSDEGTYRCL 254
               P  +I W + G +   PG+D ++              GW L++   +  D G Y CL
Sbjct: 1186 MGIPPPAIRWFR-GEEPVSPGEDTYLLAG-----------GWMLKMTQTQEQDSGLYSCL 1233

Query: 255  GRNALGQVEAPASLTVLTPDQLNSTGIPQL 284
              N  G+     S+ VL P  + +  + ++
Sbjct: 1234 ASNEAGEARRNFSVEVLVPPSIENEDLEEV 1263



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 32/141 (22%), Positives = 50/141 (35%), Gaps = 17/141 (12%)

Query: 137 SDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           SD   Y+  C+   A  A   A     +  P   G      PY    V G+ V   C   
Sbjct: 375 SDAGVYT--CKASNAVGAAEKATRLDVYVPPTIEGAG--GRPYVVKAVAGRPVALECVAR 430

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTG-WLQIQAVRPSDEGTYRCLG 255
            +P  ++ W  +GL +                  R E  G  L++++   +  G Y C+ 
Sbjct: 431 GHPSPTLSWHHEGLPVA------------ESNESRLETDGSVLRLESPGEASSGLYSCVA 478

Query: 256 RNALGQVEAPASLTVLTPDQL 276
            +  G+     S+ V  P QL
Sbjct: 479 SSPAGEAVLQYSVEVQVPPQL 499



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 33/139 (23%), Positives = 49/139 (35%), Gaps = 23/139 (16%)

Query: 138  DGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFA 197
            D  TYS +  + EA  AR    LTV  P   E   Q    P +     G  +   C+   
Sbjct: 2276 DSGTYSCVA-VSEAGEARRHFQLTVMEPPHIEDSGQ----PTELSLTPGAPMELLCDAQG 2330

Query: 198  YPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRN 257
             P  +I W KDG  +    ++   +                  + +R  D G Y CL  +
Sbjct: 2331 TPQPNITWHKDGQALTRLENNSRAT------------------RVLRVRDAGLYTCLAES 2372

Query: 258  ALGQVEAPASLTVLTPDQL 276
              G +E    + V  P  +
Sbjct: 2373 PAGAIEKSFRVRVQAPPNI 2391



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 19/110 (17%)

Query: 167 PCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFR 226
           P   GP +V+ P          V   C     P  ++ W KDG  +  P   P + V F 
Sbjct: 792 PSLPGPVLVNTP----------VRLTCNATGAPSPTLMWLKDGNPVS-PAGTPGLQV-FP 839

Query: 227 GGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
           GG         L + + R SD G Y C+  +A+G+      L V  P  +
Sbjct: 840 GGRV-------LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSI 882



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 26/86 (30%), Positives = 34/86 (39%), Gaps = 11/86 (12%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            GQ     C V  +P   + W KDG  +   GD  HIS               LQ+     
Sbjct: 1269 GQTAHLMCNVTGHPQPKLTWFKDGRPLAR-GDAHHISPD----------GVLLQVLQANL 1317

Query: 246  SDEGTYRCLGRNALGQVEAPASLTVL 271
            S  G Y C+  NA+G+      L+VL
Sbjct: 1318 SSAGHYSCIAANAVGEKTKHFQLSVL 1343



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 11/84 (13%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            C     P  ++ W +DG  +   G +  + +Q +G          L ++  + +  G Y 
Sbjct: 1089 CNATGKPPPTVTWERDGQPV---GAELGLQLQNQGQS--------LHVERAQAAHTGRYS 1137

Query: 253  CLGRNALGQVEAPASLTVLTPDQL 276
            C+  N  G+ E    L+VL P +L
Sbjct: 1138 CVAENLAGRAERKFELSVLVPPEL 1161



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 12/75 (16%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            G  +   C V   P+  I W KDGL ++      H+  Q + G         L I     
Sbjct: 3042 GGSIQLDCVVRGDPVPDIHWIKDGLPLR----GSHLRHQLQNGS--------LTIHRTER 3089

Query: 246  SDEGTYRCLGRNALG 260
             D G Y+CL  N +G
Sbjct: 3090 DDAGRYQCLAENEMG 3104



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 36/149 (24%), Positives = 46/149 (30%), Gaps = 36/149 (24%)

Query: 147  RLQEAA-RARPDANLTVAHPGPCESG------------------------PQIVSHPYDT 181
            RLQ+ A R  P   L +  PGP +S                         P I     D 
Sbjct: 2616 RLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDF 2675

Query: 182  WNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQ 241
                   V+  C     P  ++ W K G  +             RG   R   +G L+I 
Sbjct: 2676 TVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGA-----------RGSGYRVSPSGALEIG 2724

Query: 242  AVRPSDEGTYRCLGRNALGQVEAPASLTV 270
               P   G Y C  RN+ G       LTV
Sbjct: 2725 QALPIHAGRYTCSARNSAGVAHKHVFLTV 2753



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 34/134 (25%), Positives = 47/134 (35%), Gaps = 18/134 (13%)

Query: 137 SDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           SD   YS +  +      R D  L V  P      P I+    +   V  + V   C+  
Sbjct: 852 SDSGRYSCVA-VSAVGEDRQDVVLQVHMP------PSILGEELNVSVVANESVALECQSH 904

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGR 256
           A P   + W KDG  ++ P    H+S               LQ+      D G Y C   
Sbjct: 905 AMPPPVLSWWKDGRPLE-PRPGVHLSAD----------KALLQVDRADVWDAGHYTCEAL 953

Query: 257 NALGQVEAPASLTV 270
           N  G+ E   +L V
Sbjct: 954 NQAGRSEKHYNLNV 967



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 21/95 (22%), Positives = 37/95 (38%), Gaps = 11/95 (11%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            C     P+ +I W ++GL        P + V   G          LQ+     +D  +Y 
Sbjct: 1676 CPALGNPVPTISWLQNGLPFS---PSPRLQVLEDGQV--------LQVSTAEVADAASYM 1724

Query: 253  CLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSL 287
            C+  N  G  E   +L V  P ++    + Q+ ++
Sbjct: 1725 CVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAI 1759



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 34/151 (22%), Positives = 52/151 (34%), Gaps = 19/151 (12%)

Query: 124  PLCACRSQSPLCGSDGHTYSQICRLQEAARA-RPDANLTVAHPGPCESGPQIVSHPYDTW 182
            P  + R Q  L    GH    +C    +A + R   +L V  P      P I   P +  
Sbjct: 2533 PEGSLRIQPVLAQDAGH---YLCLASNSAGSDRQGRDLRVLEP------PAIAPSPSNLT 2583

Query: 183  NVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQA 242
                   +  CE    P   + W KDG  +           + + G  R   +  L + A
Sbjct: 2584 LTAHTPALLPCEASGSPKPLVVWWKDGQKLDF---------RLQQGAYRLLPSNALLLTA 2634

Query: 243  VRPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
              P D   + C+  N +G+      +TV  P
Sbjct: 2635 PGPQDSAQFECVVSNEVGEAHRLYQVTVHVP 2665



 Score = 32.7 bits (73), Expect = 0.41
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 227 GGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
           G P  + +   LQI+ V   DEG Y C   N  G+ +   +L VL P  +
Sbjct: 648 GIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNI 697



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 14/39 (35%), Positives = 21/39 (53%)

Query: 238 LQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
           L+I+  + SD G+YRC+  N  G  E    L V  P ++
Sbjct: 750 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRI 788



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 11/81 (13%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            C+  A P   + W ++   +   GD+  +    +GG         LQI  VR  + G Y 
Sbjct: 1581 CDTNAIPPPDLTWYREDQPLSA-GDEVSV---LQGGRV-------LQIPLVRAENAGRYS 1629

Query: 253  CLGRNALGQVEAPASLTVLTP 273
            C   N +G+      L VLTP
Sbjct: 1630 CKASNEVGEDWLHYELLVLTP 1650



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 17/94 (18%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTG---WLQIQA 242
            G+ V   C V   P   + W KDGL + L               QR  + G    L+I  
Sbjct: 2137 GELVTMVCPVRGSPPIHVSWLKDGLPLPL--------------SQRTLLHGSGHTLRISK 2182

Query: 243  VRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
            V+ +D G + C+  +  G  +   +L V  P  L
Sbjct: 2183 VQLADAGIFTCVAASPAGVADRNFTLQVQVPPVL 2216


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 53/178 (29%), Positives = 70/178 (39%), Gaps = 33/178 (18%)

Query: 121  VPEPLCACRSQSPLCGSDGHTYSQICRLQEA-------ARARP----DANLTVAHPGPCE 169
            +P PL    SQ  L    GHT  +I ++Q A         A P    D N T+    P  
Sbjct: 2070 LPLPL----SQRTLLHGSGHTL-RISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPV 2124

Query: 170  SGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGP 229
              P  V    D   V G  V   CE    P+  + W KDG        +P +S     GP
Sbjct: 2125 LEP--VEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDG--------EPLLSQSLEQGP 2174

Query: 230  QRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSL 287
                    LQ++AV   D GTY C+  +  G+      LTV+ P  +  +G P   SL
Sbjct: 2175 S-------LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSL 2225



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 13/116 (11%)

Query: 169  ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
            ++ P +   P     V  ++V+  CE    P  +I W+K+GL++        +S Q   G
Sbjct: 2663 QASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATG-----VSTQVLPG 2717

Query: 229  PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQL 284
                   G L+I    P D G Y C+ +N+ G       L V  P  + + G+P L
Sbjct: 2718 -------GQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIEN-GLPDL 2765



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 11/90 (12%)

Query: 189  VIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDE 248
            ++  C V A P   I W +DG+ +Q   +D H     RG   RF     LQ+QA+  +D 
Sbjct: 2317 LVLECSVEAEPAPKITWHRDGIVLQ---EDAHTQFPERG---RF-----LQLQALSTADS 2365

Query: 249  GTYRCLGRNALGQVEAPASLTVLTPDQLNS 278
            G Y C  RNA G       + + T   + S
Sbjct: 2366 GDYSCTARNAAGSTSVAFRVEIHTVPTIRS 2395



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 13/90 (14%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDD--PHISVQFRGGPQRFEVTGWLQIQAV 243
            GQ+V   CE    P   + W KDG  +   G D  PH+     GG         L ++ +
Sbjct: 1950 GQEVRLDCEADGQPPPDVAWLKDGSPL---GQDMGPHLRFYLDGGS--------LVLKGL 1998

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
            R SD G Y C+  N  G+     ++ VL P
Sbjct: 1999 RASDAGAYTCVAHNPAGEDARLHTVNVLVP 2028



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 24/98 (24%), Positives = 44/98 (44%), Gaps = 11/98 (11%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
            V G  ++  C+V   P  ++ W KD + ++       +S   RGG         LQ+  +
Sbjct: 1855 VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVS---RGGR--------LQLSRL 1903

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGI 281
            +P+  GTY C+  N   +      + VL   ++ S+G+
Sbjct: 1904 QPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGV 1941



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 46/147 (31%), Positives = 60/147 (40%), Gaps = 20/147 (13%)

Query: 138 DGHTYSQICRLQ-EAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           D   YS  CR + +A  A+ D +L V  P P   G        +   + G DV   C   
Sbjct: 98  DSGLYS--CRAENQAGTAQRDFHLLVLTP-PSVLGAGAAQ---EVLGLAGADVELQCWTS 151

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGR 256
             P   +EW KD   + LPG  PH+ VQ  G  Q   +TG          DEG Y+C+  
Sbjct: 152 GVPTPQVEWTKDRQPV-LPGG-PHLQVQEDG--QVLRITG------SHVGDEGRYQCVAF 201

Query: 257 NALGQVEAPASLTVLTPDQL---NSTG 280
           +  GQ      L V  P  +   N TG
Sbjct: 202 SPAGQQARDFQLRVHAPPTIWGSNETG 228



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 15/127 (11%)

Query: 148  LQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNV-TGQDVIFGCEVFAYPMASIEWR 206
            L  A R +    L+V  P      P+    P D   V  G   +  CE  A P  ++ W 
Sbjct: 1729 LNAAGRDQKLVQLSVLVPPAFRQAPR---GPQDAVLVRVGDKAVLSCETDALPEPTVTWY 1785

Query: 207  KDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPA 266
            KDG  + L       +   RGG +       L+IQ  + SD+G Y C   N  G+     
Sbjct: 1786 KDGQPLVLA----QRTQALRGGQR-------LEIQEAQVSDKGLYSCKVSNVAGEAVRTF 1834

Query: 267  SLTVLTP 273
            +LTV  P
Sbjct: 1835 TLTVQVP 1841



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 31/102 (30%), Positives = 42/102 (41%), Gaps = 12/102 (11%)

Query: 169  ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
            +S P     P D    +G DV   C+    P  +IEW + G  ++        S + R  
Sbjct: 3024 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRA-------SRRLRTL 3076

Query: 229  PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
            P      G L ++ V   D GTY C+  N LG   A A L V
Sbjct: 3077 PD-----GSLWLENVETGDAGTYDCVAHNLLGSATARAFLVV 3113



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 44/144 (30%), Positives = 56/144 (38%), Gaps = 26/144 (18%)

Query: 134  LCGSDGHTYSQICRLQEAARARPDANLTVAHPGPC-ESGPQIVSHPYDTWNVT-GQDVIF 191
            L  +D   YS  C  + AA +   A     H  P   SGP  V       NV+  Q  + 
Sbjct: 2360 LSTADSGDYS--CTARNAAGSTSVAFRVEIHTVPTIRSGPPAV-------NVSVNQTALL 2410

Query: 192  GCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVT--GWLQIQAVRPSDEG 249
             C+    P   + WRKD + +     DP           RFE+   G L+IQ V   D G
Sbjct: 2411 PCQADGVPAPLVSWRKDRVPL-----DPR--------SPRFEILPEGSLRIQPVLAQDAG 2457

Query: 250  TYRCLGRNALGQVEAPASLTVLTP 273
             Y CL  N+ G       L VL P
Sbjct: 2458 HYLCLASNSAGSDRQGRDLRVLEP 2481



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 30/88 (34%), Positives = 35/88 (39%), Gaps = 11/88 (12%)

Query: 193 CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
           CE    P  +I W KDG    LP       V  RGG Q       LQ+   + SD G Y 
Sbjct: 242 CEARGVPTPNITWFKDGA--LLPTSTK--VVYTRGGRQ-------LQLGRAQSSDAGVYT 290

Query: 253 CLGRNALGQVEAPASLTVLTPDQLNSTG 280
           C   NA+G  E    L V  P  +   G
Sbjct: 291 CKASNAVGAAEKATRLDVYVPPTIEGAG 318



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 11/103 (10%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            CE +A P  +I W KDG  +      P   +Q  G  +       LQIQ  + SD G Y 
Sbjct: 1379 CESWAVPPPTIRWYKDGQPVT-----PSSRLQVLGEGRL------LQIQPTQVSDSGRYL 1427

Query: 253  CLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPEEEA 295
            C+  N  G+ +   ++ +  P      G        L  EEEA
Sbjct: 1428 CVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEA 1470



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 4/104 (3%)

Query: 184 VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLP----GDDPHISVQFRGGPQRFEVTGWLQ 239
           + GQ +   C+   +P+  I W KD   + +P    G    +     GG +  +    L 
Sbjct: 31  MAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLH 90

Query: 240 IQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQ 283
              ++  D G Y C   N  G  +    L VLTP  +   G  Q
Sbjct: 91  FPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQ 134



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 13/110 (11%)

Query: 180  DTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQ 239
            D     G      C+    P  +I W KDG  +   G +   ++Q          +G L 
Sbjct: 2764 DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVS--GAEGKFTIQ---------PSGELL 2812

Query: 240  IQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNL 289
            ++ +   D GTY C   NA+G+      LT+L       T +P  RSL L
Sbjct: 2813 VKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVF--TTLPGDRSLRL 2860



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 17/100 (17%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            CE  A+P  +I W KDG   +        ++Q   G      T  LQI   +  D G Y 
Sbjct: 1281 CEALAFPSPNITWMKDGAPFEASR-----NIQLLPG------THGLQILNAQKEDAGQYT 1329

Query: 253  CLGRNALGQVEAPASLTVLTP------DQLNSTGIPQLRS 286
            C+  N LG+      + VL P      D L   G+ ++++
Sbjct: 1330 CVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKT 1369



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 15/92 (16%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGW--LQIQ 241
            +    V   C+V A+P   + W KD   + L             G + F + G   LQ+ 
Sbjct: 1668 ILNSSVSLPCDVHAHPNPEVTWYKDSQALSL-------------GEEVFLLPGTHTLQLG 1714

Query: 242  AVRPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
              R SD G Y C   NA G+ +    L+VL P
Sbjct: 1715 RARLSDSGMYTCEALNAAGRDQKLVQLSVLVP 1746



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 28/92 (30%), Positives = 34/92 (36%), Gaps = 11/92 (11%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTG-WLQIQAVR 244
           G      CE    P   I WRKDG    LPG+          G Q     G  L +   +
Sbjct: 895 GHPTRLSCECRGVPFPKISWRKDGQ--PLPGEG--------AGLQHVSAVGRLLYLGQAQ 944

Query: 245 PSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
            + EGTY C   N +G       L V  P Q+
Sbjct: 945 LAQEGTYTCECSNVVGNSSQDLQLEVHVPPQI 976



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 35/150 (23%), Positives = 58/150 (38%), Gaps = 23/150 (15%)

Query: 140  HTYSQICRLQE-AARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTG---QDVIFGCEV 195
            HT    C  +  A RA     L+V  P      P+++       N+T      +   CE 
Sbjct: 1041 HTGRYSCVAENLAGRAERKFELSVLVP------PELIGDLDPLTNITAALHSPLTLLCEA 1094

Query: 196  FAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGW-LQIQAVRPSDEGTYRCL 254
               P  +I W + G +   PG+D ++              GW L++   +  D G Y CL
Sbjct: 1095 MGIPPPAIRWFR-GEEPVSPGEDTYLLAG-----------GWMLKMTQTQEQDSGLYSCL 1142

Query: 255  GRNALGQVEAPASLTVLTPDQLNSTGIPQL 284
              N  G+     S+ VL P  + +  + ++
Sbjct: 1143 ASNEAGEARRNFSVEVLVPPSIENEDLEEV 1172



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 32/141 (22%), Positives = 50/141 (35%), Gaps = 17/141 (12%)

Query: 137 SDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           SD   Y+  C+   A  A   A     +  P   G      PY    V G+ V   C   
Sbjct: 284 SDAGVYT--CKASNAVGAAEKATRLDVYVPPTIEGAG--GRPYVVKAVAGRPVALECVAR 339

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTG-WLQIQAVRPSDEGTYRCLG 255
            +P  ++ W  +GL +                  R E  G  L++++   +  G Y C+ 
Sbjct: 340 GHPSPTLSWHHEGLPVA------------ESNESRLETDGSVLRLESPGEASSGLYSCVA 387

Query: 256 RNALGQVEAPASLTVLTPDQL 276
            +  G+     S+ V  P QL
Sbjct: 388 SSPAGEAVLQYSVEVQVPPQL 408



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 33/139 (23%), Positives = 49/139 (35%), Gaps = 23/139 (16%)

Query: 138  DGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFA 197
            D  TYS +  + EA  AR    LTV  P   E   Q    P +     G  +   C+   
Sbjct: 2185 DSGTYSCVA-VSEAGEARRHFQLTVMEPPHIEDSGQ----PTELSLTPGAPMELLCDAQG 2239

Query: 198  YPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRN 257
             P  +I W KDG  +    ++   +                  + +R  D G Y CL  +
Sbjct: 2240 TPQPNITWHKDGQALTRLENNSRAT------------------RVLRVRDAGLYTCLAES 2281

Query: 258  ALGQVEAPASLTVLTPDQL 276
              G +E    + V  P  +
Sbjct: 2282 PAGAIEKSFRVRVQAPPNI 2300



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 19/110 (17%)

Query: 167 PCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFR 226
           P   GP +V+ P          V   C     P  ++ W KDG  +  P   P + V F 
Sbjct: 701 PSLPGPVLVNTP----------VRLTCNATGAPSPTLMWLKDGNPVS-PAGTPGLQV-FP 748

Query: 227 GGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
           GG         L + + R SD G Y C+  +A+G+      L V  P  +
Sbjct: 749 GGRV-------LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSI 791



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 26/86 (30%), Positives = 34/86 (39%), Gaps = 11/86 (12%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            GQ     C V  +P   + W KDG  +   GD  HIS               LQ+     
Sbjct: 1178 GQTAHLMCNVTGHPQPKLTWFKDGRPLAR-GDAHHISPD----------GVLLQVLQANL 1226

Query: 246  SDEGTYRCLGRNALGQVEAPASLTVL 271
            S  G Y C+  NA+G+      L+VL
Sbjct: 1227 SSAGHYSCIAANAVGEKTKHFQLSVL 1252



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 12/75 (16%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            G  +   C V   P+  I W KDGL ++      H+  Q + G         L I+    
Sbjct: 2951 GGSIQLDCVVRGDPVPDIHWIKDGLPLR----GSHLRHQLQNGS--------LTIRRTER 2998

Query: 246  SDEGTYRCLGRNALG 260
             D G Y+CL  N +G
Sbjct: 2999 DDAGRYQCLAENEMG 3013



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 11/84 (13%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            C     P  ++ W +DG  +   G +  + +Q +G          L ++  + +  G Y 
Sbjct: 998  CNATGKPPPTVTWERDGQPV---GAELGLQLQNQGQS--------LHVERAQAAHTGRYS 1046

Query: 253  CLGRNALGQVEAPASLTVLTPDQL 276
            C+  N  G+ E    L+VL P +L
Sbjct: 1047 CVAENLAGRAERKFELSVLVPPEL 1070



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 36/149 (24%), Positives = 46/149 (30%), Gaps = 36/149 (24%)

Query: 147  RLQEAA-RARPDANLTVAHPGPCESG------------------------PQIVSHPYDT 181
            RLQ+ A R  P   L +  PGP +S                         P I     D 
Sbjct: 2525 RLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDF 2584

Query: 182  WNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQ 241
                   V+  C     P  ++ W K G  +             RG   R   +G L+I 
Sbjct: 2585 TVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGA-----------RGSGYRVSPSGALEIG 2633

Query: 242  AVRPSDEGTYRCLGRNALGQVEAPASLTV 270
               P   G Y C  RN+ G       LTV
Sbjct: 2634 QALPIHAGRYTCSARNSAGVAHKHVFLTV 2662



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 34/134 (25%), Positives = 46/134 (34%), Gaps = 18/134 (13%)

Query: 137 SDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           SD   YS +  +      R D  L V  P      P I+    +   V  + V   C+  
Sbjct: 761 SDSGRYSCVA-VSAVGEDRQDVVLQVHMP------PSILGEELNVSVVANESVALECQSH 813

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGR 256
           A P   + W KDG  ++ P    H+S               LQ+      D G Y C   
Sbjct: 814 AMPPPVLSWWKDGRPLE-PRPGVHLSAD----------KALLQVDRADVWDAGHYTCEAL 862

Query: 257 NALGQVEAPASLTV 270
           N  G  E   +L V
Sbjct: 863 NQAGHSEKHYNLNV 876



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 21/95 (22%), Positives = 37/95 (38%), Gaps = 11/95 (11%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            C     P+ +I W ++GL        P + V   G          LQ+     +D  +Y 
Sbjct: 1585 CPALGNPVPTISWLQNGLPFS---PSPRLQVLEDGQV--------LQVSTAEVADAASYM 1633

Query: 253  CLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSL 287
            C+  N  G  E   +L V  P ++    + Q+ ++
Sbjct: 1634 CVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAI 1668



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 34/151 (22%), Positives = 52/151 (34%), Gaps = 19/151 (12%)

Query: 124  PLCACRSQSPLCGSDGHTYSQICRLQEAARA-RPDANLTVAHPGPCESGPQIVSHPYDTW 182
            P  + R Q  L    GH    +C    +A + R   +L V  P      P I   P +  
Sbjct: 2442 PEGSLRIQPVLAQDAGH---YLCLASNSAGSDRQGRDLRVLEP------PAIAPSPSNLT 2492

Query: 183  NVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQA 242
                   +  CE    P   + W KDG  +           + + G  R   +  L + A
Sbjct: 2493 LTAHTPALLPCEASGSPKPLVVWWKDGQKLDF---------RLQQGAYRLLPSNALLLTA 2543

Query: 243  VRPSDEGTYRCLGRNALGQVEAPASLTVLTP 273
              P D   + C+  N +G+      +TV  P
Sbjct: 2544 PGPQDSAQFECVVSNEVGEAHRLYQVTVHVP 2574



 Score = 32.7 bits (73), Expect = 0.41
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 227 GGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
           G P  + +   LQI+ V   DEG Y C   N  G+ +   +L VL P  +
Sbjct: 557 GIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNI 606



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 14/39 (35%), Positives = 21/39 (53%)

Query: 238 LQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
           L+I+  + SD G+YRC+  N  G  E    L V  P ++
Sbjct: 659 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRI 697



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 11/81 (13%)

Query: 193  CEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYR 252
            C+  A P   + W ++   +   GD+  +    +GG         LQI  VR  + G Y 
Sbjct: 1490 CDTNAIPPPDLTWYREDQPLSA-GDEVSV---LQGGRV-------LQIPLVRAENAGRYS 1538

Query: 253  CLGRNALGQVEAPASLTVLTP 273
            C   N +G+      L VLTP
Sbjct: 1539 CKASNEVGEDWLHYELLVLTP 1559



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 17/94 (18%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTG---WLQIQA 242
            G+ V   C V   P   + W KDGL + L               QR  + G    L+I  
Sbjct: 2046 GELVTMVCPVRGSPPIHVSWLKDGLPLPL--------------SQRTLLHGSGHTLRISK 2091

Query: 243  VRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQL 276
            V+ +D G + C+  +  G  +   +L V  P  L
Sbjct: 2092 VQLADAGIFTCVAASPAGVADRNFTLQVQVPPVL 2125


>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
           ROBO2a [Homo sapiens]
          Length = 1394

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 37/102 (36%), Positives = 48/102 (47%), Gaps = 7/102 (6%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P+IV HP D     G+     C+    P  +IEW KDG  ++   DDP            
Sbjct: 47  PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 106

Query: 232 FEVTGWLQIQAVRPS--DEGTYRCLGRNALGQ-VEAPASLTV 270
           F    +L+I   R S  DEG+Y C+ RN LG+ V   ASL V
Sbjct: 107 F----FLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEV 144



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 23/141 (16%)

Query: 137 SDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           SD   Y+ +       R    A LTV         P  +  P +   +  + V F C+V 
Sbjct: 212 SDAGMYTCVGTNMVGERDSDPAELTVFER------PTFLRRPINQVVLEEEAVEFRCQVQ 265

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTG--WLQIQAVRPSDEGTYRCL 254
             P  ++ W+KD  D+             RG   R+++     L+I+    +DEGTY C+
Sbjct: 266 GDPQPTVRWKKDDADLP------------RG---RYDIKDDYTLRIKKTMSTDEGTYMCI 310

Query: 255 GRNALGQVEAPASLTVLTPDQ 275
             N +G++EA A+LTV  P Q
Sbjct: 311 AENRVGKMEASATLTVRAPPQ 331



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 40/134 (29%), Positives = 51/134 (38%), Gaps = 11/134 (8%)

Query: 137 SDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           +D  TY  I       +    A LTV  P      PQ V  P D     G+ V F CE  
Sbjct: 302 TDEGTYMCIAE-NRVGKMEASATLTVRAP------PQFVVRPRDQIVAQGRTVTFPCETK 354

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGR 256
             P  ++ W+K+G    L  + P    Q          TG L I  ++ SD G Y C   
Sbjct: 355 GNPQPAVFWQKEGSQNLLFPNQP----QQPNSRCSVSPTGDLTITNIQRSDAGYYICQAL 410

Query: 257 NALGQVEAPASLTV 270
              G + A A L V
Sbjct: 411 TVAGSILAKAQLEV 424



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 14/96 (14%)

Query: 177 HPYDTWNVTGQDVIFGCEV-FAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVT 235
           +P D     G+  I  C+    +P  +I W+KD + I    DD    +  RGG       
Sbjct: 154 NPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRI----DDKEERISIRGGK------ 203

Query: 236 GWLQIQAVRPSDEGTYRCLGRNALGQVEA-PASLTV 270
             L I   R SD G Y C+G N +G+ ++ PA LTV
Sbjct: 204 --LMISNTRKSDAGMYTCVGTNMVGERDSDPAELTV 237



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 11/99 (11%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P I+  P +         +  C+    P+  I W K+G     PG DP  ++Q +G    
Sbjct: 434 PIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTF--PGRDPRATIQEQGT--- 488

Query: 232 FEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
                 LQI+ +R SD GTY C+  ++ G+    A L V
Sbjct: 489 ------LQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 521


>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
           ROBO2b [Homo sapiens]
          Length = 1378

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 37/102 (36%), Positives = 48/102 (47%), Gaps = 7/102 (6%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P+IV HP D     G+     C+    P  +IEW KDG  ++   DDP            
Sbjct: 31  PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90

Query: 232 FEVTGWLQIQAVRPS--DEGTYRCLGRNALGQ-VEAPASLTV 270
           F    +L+I   R S  DEG+Y C+ RN LG+ V   ASL V
Sbjct: 91  F----FLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEV 128



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 23/141 (16%)

Query: 137 SDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           SD   Y+ +       R    A LTV         P  +  P +   +  + V F C+V 
Sbjct: 196 SDAGMYTCVGTNMVGERDSDPAELTVFER------PTFLRRPINQVVLEEEAVEFRCQVQ 249

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTG--WLQIQAVRPSDEGTYRCL 254
             P  ++ W+KD  D+             RG   R+++     L+I+    +DEGTY C+
Sbjct: 250 GDPQPTVRWKKDDADLP------------RG---RYDIKDDYTLRIKKTMSTDEGTYMCI 294

Query: 255 GRNALGQVEAPASLTVLTPDQ 275
             N +G++EA A+LTV  P Q
Sbjct: 295 AENRVGKMEASATLTVRAPPQ 315



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 40/134 (29%), Positives = 51/134 (38%), Gaps = 11/134 (8%)

Query: 137 SDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVF 196
           +D  TY  I       +    A LTV  P      PQ V  P D     G+ V F CE  
Sbjct: 286 TDEGTYMCIAE-NRVGKMEASATLTVRAP------PQFVVRPRDQIVAQGRTVTFPCETK 338

Query: 197 AYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGR 256
             P  ++ W+K+G    L  + P    Q          TG L I  ++ SD G Y C   
Sbjct: 339 GNPQPAVFWQKEGSQNLLFPNQP----QQPNSRCSVSPTGDLTITNIQRSDAGYYICQAL 394

Query: 257 NALGQVEAPASLTV 270
              G + A A L V
Sbjct: 395 TVAGSILAKAQLEV 408



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 14/96 (14%)

Query: 177 HPYDTWNVTGQDVIFGCEV-FAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVT 235
           +P D     G+  I  C+    +P  +I W+KD + I    DD    +  RGG       
Sbjct: 138 NPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRI----DDKEERISIRGGK------ 187

Query: 236 GWLQIQAVRPSDEGTYRCLGRNALGQVEA-PASLTV 270
             L I   R SD G Y C+G N +G+ ++ PA LTV
Sbjct: 188 --LMISNTRKSDAGMYTCVGTNMVGERDSDPAELTV 221



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 11/99 (11%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P I+  P +         +  C+    P+  I W K+G     PG DP  ++Q +G    
Sbjct: 418 PIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTF--PGRDPRATIQEQGT--- 472

Query: 232 FEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
                 LQI+ +R SD GTY C+  ++ G+    A L V
Sbjct: 473 ------LQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 505


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 12/103 (11%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P   S P DT    G +V   C     P  +I W KDG+ +   G   HIS +       
Sbjct: 525 PVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKF-HISPE------- 576

Query: 232 FEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPD 274
               G+L I  V P+D G Y C+ RN +G       L+V  PD
Sbjct: 577 ----GFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPD 615



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 33/99 (33%), Positives = 41/99 (41%), Gaps = 12/99 (12%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           PQ    P D   + GQ V F CE    P   I W K G   QL  D  H+ +        
Sbjct: 433 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGG--SQLSVDRRHLVLS------- 483

Query: 232 FEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
              +G L+I  V   D+G Y C   N +G  +  A LTV
Sbjct: 484 ---SGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTV 519



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 31/119 (26%), Positives = 49/119 (41%), Gaps = 12/119 (10%)

Query: 145 ICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIE 204
           IC      + R  A +T      CE  P+I S P D    +G  V F C     P   I 
Sbjct: 221 ICEYPRRIQGRSVATITPEELN-CER-PRITSEPQDADVTSGNTVYFTCRAEGNPKPEII 278

Query: 205 WRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVE 263
           W ++  ++ +  D     +            G L IQ  + +D+G Y+C+ +N  G+V+
Sbjct: 279 WLRNNNELSMKTDSRLNLLD----------DGTLMIQNTQETDQGIYQCMAKNVAGEVK 327



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 32/108 (29%), Positives = 42/108 (38%), Gaps = 11/108 (10%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P  V  P +T  + G+ V   C    +P   I W + G    LP D P +++   GG   
Sbjct: 342 PTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR-GDRTPLPVD-PRVNITPSGG--- 396

Query: 232 FEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNST 279
                 L IQ V   D G Y C   N +  V A A + V    Q   T
Sbjct: 397 ------LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVT 438


>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
           sapiens]
          Length = 2113

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 41/135 (30%), Positives = 53/135 (39%), Gaps = 17/135 (12%)

Query: 141 TYSQICRLQEAARARPDANLTVAHPGPCESGPQIVS--HPYDTWNVTGQDVIFGCEVFAY 198
           TY  I + + +   R      ++   P ES P I+   H  + W   G  V   C    Y
Sbjct: 255 TYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVW--AGHTVELPCTASGY 312

Query: 199 PMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNA 258
           P+ +I W KDG    LP D                +TG L I  +R  D GTY C   N 
Sbjct: 313 PIPAIRWLKDGR--PLPADSRWTK----------RITG-LTISDLRTEDSGTYICEVTNT 359

Query: 259 LGQVEAPASLTVLTP 273
            G  EA   L V+ P
Sbjct: 360 FGSAEATGILMVIDP 374



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 11/83 (13%)

Query: 171 GPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQ 230
           GP  +    +   V G+D +  C V  YP  SI+W KD L   LP  D H  V F  G  
Sbjct: 564 GPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL--LLP--DNHRQVVFENGTL 619

Query: 231 RFEVTGWLQIQAVRPSDEGTYRC 253
           +            +  DEG Y C
Sbjct: 620 KL-------TDVQKGMDEGEYLC 635



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 11/132 (8%)

Query: 145  ICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIE 204
            +  +  A R      +T+   G   +  +I+S          +DV   C     P  +++
Sbjct: 1325 VAAVTSAGRGNSSEKVTIEPAGKAPA--KIISFGGTVTTPWMKDVRLPCNSVGDPAPAVK 1382

Query: 205  WRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEA 264
            W KD  D  +P     +S+    G +     G L ++AV+  D G Y C   N  G    
Sbjct: 1383 WTKDSEDSAIP-----VSMD---GHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGFDTI 1434

Query: 265  PASLTV-LTPDQ 275
              +L V + PDQ
Sbjct: 1435 IVNLLVQVPPDQ 1446



 Score = 31.6 bits (70), Expect = 0.91
 Identities = 25/107 (23%), Positives = 40/107 (37%), Gaps = 4/107 (3%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P+IVS   +     G+     C     P  ++ W  D  D  +  D  H + Q+      
Sbjct: 468 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALD--DEPIVRDGSHRTNQYTMSDGT 525

Query: 232 FEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNS 278
                 + +   +  D G YRC  RN +G  E  A + V  P  + +
Sbjct: 526 --TISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRA 570



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 28/119 (23%), Positives = 44/119 (36%), Gaps = 27/119 (22%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQR 231
           P+ V  P +   + G+  +  C V  YP   + W+                 +  G PQ+
Sbjct: 750 PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWK---------------HAKGSGNPQQ 794

Query: 232 FE---VTGWLQ--------IQAVRPSDEGTYRCLGRNALG-QVEAPASLTVLTPDQLNS 278
           +    +TG +Q        I+ V   D G Y C   N +G  +     LTV  P  + S
Sbjct: 795 YHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITS 853



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 27/89 (30%), Positives = 34/89 (38%), Gaps = 10/89 (11%)

Query: 186 GQDVIFGCEVFAYPMA-SIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVR 244
           GQ +   C V +  M   I WRKDG  + + G    I  +        E    LQI +V 
Sbjct: 670 GQLLYIPCVVSSGDMPIRITWRKDG-QVIISGSGVTIESK--------EFMSSLQISSVS 720

Query: 245 PSDEGTYRCLGRNALGQVEAPASLTVLTP 273
               G Y C+  NA   V     L V  P
Sbjct: 721 LKHNGNYTCIASNAAATVSRERQLIVRVP 749


>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
          Length = 1863

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/102 (34%), Positives = 40/102 (39%), Gaps = 12/102 (11%)

Query: 169 ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
           E  P   S   D   + GQD +  C V   P+  I W  +G  IQ         V     
Sbjct: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV----- 565

Query: 229 PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
                    L IQ   P D GTY CL  NALGQV   A +TV
Sbjct: 566 -------AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 9/103 (8%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           GQ   F C++   P   + W K  + +Q       +SV  + G Q  E+ G      V  
Sbjct: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQ---PSARVSVSEKNGMQVLEIHG------VNQ 225

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLN 288
            D G Y CL  N  G+    A L++   D  N + + + ++ N
Sbjct: 226 DDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/118 (27%), Positives = 47/118 (39%), Gaps = 9/118 (7%)

Query: 151 AARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGL 210
           A   R  A LTV  P    + P  +S P       GQ V+  C +   P  ++ W +DG 
Sbjct: 701 AGEVRTQAVLTVQEPHD-GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759

Query: 211 DIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASL 268
              L  D  H  V       + E    L ++ V+P   G Y  L +N +G+     SL
Sbjct: 760 --ALCKDTGHFEV------LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 9/101 (8%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            G+ ++  C+V + P A+I W  +G  ++        + +F    Q   +   + I+   P
Sbjct: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLK--------TTKFIILSQEGSLCS-VSIEKALP 1162

Query: 246  SDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRS 286
             D G Y+C+ +N  GQ E    +TV       +T  P+++S
Sbjct: 1163 EDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 13/116 (11%)

Query: 158 ANLTVAHPGPCESG-PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPG 216
           AN  +   G  +S  P+  S P        Q V F CEV   P   + W  +G  ++   
Sbjct: 399 ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR--- 455

Query: 217 DDPHISVQFRGGPQRFEVTG--WLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
                  +  G  + +E  G  +L +   R  D GTY C   NA GQ+    +L V
Sbjct: 456 -------RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 9/88 (10%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G  V    +V   P   + W  +G +IQ   +D H   +   G Q       L IQ V P
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQR---GTQHS-----LCIQEVFP 687

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTP 273
            D GTY C   N+ G+V   A LTV  P
Sbjct: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQEP 715



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 25/97 (25%), Positives = 38/97 (39%), Gaps = 8/97 (8%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
            V G    F C++  YP   + W KD   I+   +  H  + +       +    L I  V
Sbjct: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDE-----DGNCSLIISDV 1821

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTG 280
               D+  Y C   N+LG+    A L V T ++    G
Sbjct: 1822 CGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1858



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 28/104 (26%), Positives = 35/104 (33%), Gaps = 8/104 (7%)

Query: 167 PCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFR 226
           P    P  +  P +     G    F   V  YP   + W ++G  I   G    +    R
Sbjct: 28  PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT-SGGRFLLDCGIR 86

Query: 227 GGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
           G       T  L I AV   D G Y C   N  G  +    LTV
Sbjct: 87  G-------TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 31/101 (30%), Positives = 42/101 (41%), Gaps = 11/101 (10%)

Query: 172  PQIVSHPYDTWNVTGQDV-IFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQ 230
            PQI+  P D     G+ V +FG      P+ +  W K    IQ   +  H+ V+      
Sbjct: 1238 PQIIQFPEDQKVRAGESVELFGKVTGTQPI-TCTWMKFRKQIQ---ESEHMKVE------ 1287

Query: 231  RFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVL 271
              E    L I A R    G Y  L  N LG  +A  +LTV+
Sbjct: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328


>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
          Length = 1914

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/102 (34%), Positives = 40/102 (39%), Gaps = 12/102 (11%)

Query: 169 ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
           E  P   S   D   + GQD +  C V   P+  I W  +G  IQ         V     
Sbjct: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV----- 565

Query: 229 PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
                    L IQ   P D GTY CL  NALGQV   A +TV
Sbjct: 566 -------AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 9/103 (8%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           GQ   F C++   P   + W K  + +Q       +SV  + G Q  E+ G      V  
Sbjct: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQ---PSARVSVSEKNGMQVLEIHG------VNQ 225

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLN 288
            D G Y CL  N  G+    A L++   D  N + + + ++ N
Sbjct: 226 DDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/118 (27%), Positives = 47/118 (39%), Gaps = 9/118 (7%)

Query: 151 AARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGL 210
           A   R  A LTV  P    + P  +S P       GQ V+  C +   P  ++ W +DG 
Sbjct: 701 AGEVRTQAVLTVQEPHD-GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759

Query: 211 DIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASL 268
              L  D  H  V       + E    L ++ V+P   G Y  L +N +G+     SL
Sbjct: 760 --ALCKDTGHFEV------LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 9/101 (8%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            G+ ++  C+V + P A+I W  +G  ++        + +F    Q   +   + I+   P
Sbjct: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLK--------TTKFIILSQEGSLCS-VSIEKALP 1162

Query: 246  SDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRS 286
             D G Y+C+ +N  GQ E    +TV       +T  P+++S
Sbjct: 1163 EDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 13/116 (11%)

Query: 158 ANLTVAHPGPCESG-PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPG 216
           AN  +   G  +S  P+  S P        Q V F CEV   P   + W  +G  ++   
Sbjct: 399 ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR--- 455

Query: 217 DDPHISVQFRGGPQRFEVTG--WLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
                  +  G  + +E  G  +L +   R  D GTY C   NA GQ+    +L V
Sbjct: 456 -------RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 9/88 (10%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G  V    +V   P   + W  +G +IQ   +D H   +   G Q       L IQ V P
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQR---GTQHS-----LCIQEVFP 687

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTP 273
            D GTY C   N+ G+V   A LTV  P
Sbjct: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQEP 715



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 25/97 (25%), Positives = 38/97 (39%), Gaps = 8/97 (8%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
            V G    F C++  YP   + W KD   I+   +  H  + +       +    L I  V
Sbjct: 1821 VEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDE-----DGNCSLIISDV 1872

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTG 280
               D+  Y C   N+LG+    A L V T ++    G
Sbjct: 1873 CGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1909



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 28/104 (26%), Positives = 35/104 (33%), Gaps = 8/104 (7%)

Query: 167 PCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFR 226
           P    P  +  P +     G    F   V  YP   + W ++G  I   G    +    R
Sbjct: 28  PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT-SGGRFLLDCGIR 86

Query: 227 GGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
           G       T  L I AV   D G Y C   N  G  +    LTV
Sbjct: 87  G-------TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 31/101 (30%), Positives = 42/101 (41%), Gaps = 11/101 (10%)

Query: 172  PQIVSHPYDTWNVTGQDV-IFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQ 230
            PQI+  P D     G+ V +FG      P+ +  W K    IQ   +  H+ V+      
Sbjct: 1238 PQIIQFPEDQKVRAGESVELFGKVTGTQPI-TCTWMKFRKQIQ---ESEHMKVE------ 1287

Query: 231  RFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVL 271
              E    L I A R    G Y  L  N LG  +A  +LTV+
Sbjct: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328


>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
          Length = 1794

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/102 (34%), Positives = 40/102 (39%), Gaps = 12/102 (11%)

Query: 169 ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
           E  P   S   D   + GQD +  C V   P+  I W  +G  IQ         V     
Sbjct: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV----- 496

Query: 229 PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
                    L IQ   P D GTY CL  NALGQV   A +TV
Sbjct: 497 -------AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 9/103 (8%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           GQ   F C++   P   + W K  + +Q       +SV  + G Q  E+ G      V  
Sbjct: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQ---PSARVSVSEKNGMQVLEIHG------VNQ 225

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLN 288
            D G Y CL  N  G+    A L++   D  N + + + ++ N
Sbjct: 226 DDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/118 (27%), Positives = 47/118 (39%), Gaps = 9/118 (7%)

Query: 151 AARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGL 210
           A   R  A LTV  P    + P  +S P       GQ V+  C +   P  ++ W +DG 
Sbjct: 632 AGEVRTQAVLTVQEPHD-GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690

Query: 211 DIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASL 268
              L  D  H  V       + E    L ++ V+P   G Y  L +N +G+     SL
Sbjct: 691 --ALCKDTGHFEV------LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 740



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 9/101 (8%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            G+ ++  C+V + P A+I W  +G  ++        + +F    Q   +   + I+   P
Sbjct: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLK--------TTKFIILSQEGSLCS-VSIEKALP 1093

Query: 246  SDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRS 286
             D G Y+C+ +N  GQ E    +TV       +T  P+++S
Sbjct: 1094 EDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1134



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 9/88 (10%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G  V    +V   P   + W  +G +IQ   +D H   +   G Q       L IQ V P
Sbjct: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQR---GTQHS-----LCIQEVFP 618

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTP 273
            D GTY C   N+ G+V   A LTV  P
Sbjct: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQEP 646



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 25/97 (25%), Positives = 38/97 (39%), Gaps = 8/97 (8%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
            V G    F C++  YP   + W KD   I+   +  H  + +       +    L I  V
Sbjct: 1701 VEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDE-----DGNCSLIISDV 1752

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTG 280
               D+  Y C   N+LG+    A L V T ++    G
Sbjct: 1753 CGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1789



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 28/104 (26%), Positives = 35/104 (33%), Gaps = 8/104 (7%)

Query: 167 PCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFR 226
           P    P  +  P +     G    F   V  YP   + W ++G  I   G    +    R
Sbjct: 28  PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT-SGGRFLLDCGIR 86

Query: 227 GGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
           G       T  L I AV   D G Y C   N  G  +    LTV
Sbjct: 87  G-------TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 31/101 (30%), Positives = 42/101 (41%), Gaps = 11/101 (10%)

Query: 172  PQIVSHPYDTWNVTGQDV-IFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQ 230
            PQI+  P D     G+ V +FG      P+ +  W K    IQ   +  H+ V+      
Sbjct: 1169 PQIIQFPEDQKVRAGESVELFGKVTGTQPI-TCTWMKFRKQIQ---ESEHMKVE------ 1218

Query: 231  RFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVL 271
              E    L I A R    G Y  L  N LG  +A  +LTV+
Sbjct: 1219 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1259


>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
          Length = 1845

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/102 (34%), Positives = 40/102 (39%), Gaps = 12/102 (11%)

Query: 169 ESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGG 228
           E  P   S   D   + GQD +  C V   P+  I W  +G  IQ         V     
Sbjct: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV----- 496

Query: 229 PQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
                    L IQ   P D GTY CL  NALGQV   A +TV
Sbjct: 497 -------AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 9/103 (8%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           GQ   F C++   P   + W K  + +Q       +SV  + G Q  E+ G      V  
Sbjct: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQ---PSARVSVSEKNGMQVLEIHG------VNQ 225

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLN 288
            D G Y CL  N  G+    A L++   D  N + + + ++ N
Sbjct: 226 DDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/118 (27%), Positives = 47/118 (39%), Gaps = 9/118 (7%)

Query: 151 AARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGL 210
           A   R  A LTV  P    + P  +S P       GQ V+  C +   P  ++ W +DG 
Sbjct: 632 AGEVRTQAVLTVQEPHD-GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690

Query: 211 DIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASL 268
              L  D  H  V       + E    L ++ V+P   G Y  L +N +G+     SL
Sbjct: 691 --ALCKDTGHFEV------LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 740



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 9/101 (8%)

Query: 186  GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
            G+ ++  C+V + P A+I W  +G  ++        + +F    Q   +   + I+   P
Sbjct: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLK--------TTKFIILSQEGSLCS-VSIEKALP 1093

Query: 246  SDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRS 286
             D G Y+C+ +N  GQ E    +TV       +T  P+++S
Sbjct: 1094 EDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1134



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 9/88 (10%)

Query: 186 GQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRP 245
           G  V    +V   P   + W  +G +IQ   +D H   +   G Q       L IQ V P
Sbjct: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQR---GTQHS-----LCIQEVFP 618

Query: 246 SDEGTYRCLGRNALGQVEAPASLTVLTP 273
            D GTY C   N+ G+V   A LTV  P
Sbjct: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQEP 646



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 25/97 (25%), Positives = 38/97 (39%), Gaps = 8/97 (8%)

Query: 184  VTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAV 243
            V G    F C++  YP   + W KD   I+   +  H  + +       +    L I  V
Sbjct: 1752 VEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDE-----DGNCSLIISDV 1803

Query: 244  RPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTG 280
               D+  Y C   N+LG+    A L V T ++    G
Sbjct: 1804 CGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1840



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 28/104 (26%), Positives = 35/104 (33%), Gaps = 8/104 (7%)

Query: 167 PCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFR 226
           P    P  +  P +     G    F   V  YP   + W ++G  I   G    +    R
Sbjct: 28  PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT-SGGRFLLDCGIR 86

Query: 227 GGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
           G       T  L I AV   D G Y C   N  G  +    LTV
Sbjct: 87  G-------TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 31/101 (30%), Positives = 42/101 (41%), Gaps = 11/101 (10%)

Query: 172  PQIVSHPYDTWNVTGQDV-IFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQ 230
            PQI+  P D     G+ V +FG      P+ +  W K    IQ   +  H+ V+      
Sbjct: 1169 PQIIQFPEDQKVRAGESVELFGKVTGTQPI-TCTWMKFRKQIQ---ESEHMKVE------ 1218

Query: 231  RFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVL 271
              E    L I A R    G Y  L  N LG  +A  +LTV+
Sbjct: 1219 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1259


>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
           netrin domain containing 1 precursor [Homo sapiens]
          Length = 548

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 73/309 (23%), Positives = 105/309 (33%), Gaps = 73/309 (23%)

Query: 7   PAAALALPVLLLLLVVLTP---PPTGARPSPGPDYLRRG-WMRLLAEGEG-CAPCRPEEC 61
           PA    LP+LLLL +       P  G+ P   P+ L    W+   +  E  C+  R ++C
Sbjct: 2   PALRPLLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQSTCERECS--RDQDC 59

Query: 62  AAPR----------GCLAGRVRDACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECRLD 111
           AA             C+A R   +       A+ EG +C    S           +C + 
Sbjct: 60  AAAEKCCINVCGLHSCVAARFPGSPAAPTTAASCEGFVCPQQGS-----------DCDIW 108

Query: 112 TGGDLSRGEVPEPLCACRSQ-----SPLCGSDGHTYSQICRLQEAARAR----------- 155
            G         +P+C CR +     S  C SDG TY   C +   A  R           
Sbjct: 109 DG---------QPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKH 159

Query: 156 ----------PDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEW 205
                     P        PG     P + S P       G      C+V   P  ++ W
Sbjct: 160 VLSWPPSSPGPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW 219

Query: 206 RKDGL---DIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQV 262
            K      ++ +  D  + +V            G L +   RP D G Y C  RNA G +
Sbjct: 220 EKQSHQRENLIMRPDQMYGNVVVTS-------IGQLVLYNARPEDAGLYTCTARNAAGLL 272

Query: 263 EAPASLTVL 271
            A   L+V+
Sbjct: 273 RADFPLSVV 281


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 42/156 (26%), Positives = 68/156 (43%), Gaps = 20/156 (12%)

Query: 139 GHTYSQI-CRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFA 197
           GHT +   C        R  A++TV     C+S P+I   P D    +G  V F C    
Sbjct: 202 GHTQAAATCEYPRRLHGRAVASVTVEEFN-CQS-PRITFEPQDVEVPSGNTVYFTCRAEG 259

Query: 198 YPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRN 257
            P   I W  +   + L  DD  ++V        F+  G L I+  R SD+G Y+C+ RN
Sbjct: 260 NPKPEIIWIHNNHSLDLE-DDTRLNV--------FD-DGTLMIRNTRESDQGVYQCMARN 309

Query: 258 ALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPEE 293
           + G+ +  +++       L  + +P   S  + P++
Sbjct: 310 SAGEAKTQSAM-------LRYSSLPAKPSFVIQPQD 338



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 28/109 (25%), Positives = 42/109 (38%), Gaps = 15/109 (13%)

Query: 172 PQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKD-GLDIQLPGDDPHISVQFRGGPQ 230
           P  V  P DT  + G      C    +P   I W +D GL++               G +
Sbjct: 330 PSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELD--------------GSR 375

Query: 231 RFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNST 279
               +  L +Q +   D G + C   N+ G V+A A++ V  P Q   T
Sbjct: 376 HVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVT 424



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 12/93 (12%)

Query: 178 PYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGW 237
           P DT    G+++   C     P   I W K+G+ I               G    +  G 
Sbjct: 517 PQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQIT------------ESGKFHVDDEGT 564

Query: 238 LQIQAVRPSDEGTYRCLGRNALGQVEAPASLTV 270
           L I      D+G Y C+ RN+ G       LTV
Sbjct: 565 LTIYDAGFPDQGRYECVARNSFGLAVTNMFLTV 597



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 18/132 (13%)

Query: 158 ANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGD 217
           AN+ V  P      PQ    P D   +    V + CE    P   I W K G  + + G 
Sbjct: 411 ANIIVQAP------PQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQ 464

Query: 218 DPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLN 277
              +S            +G L+I      D+G Y C   ++LG  +    LTV       
Sbjct: 465 HTVLS------------SGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAV 512

Query: 278 STGIPQLRSLNL 289
            T +PQ  S+ +
Sbjct: 513 FTQLPQDTSVEV 524


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.139    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,334,466
Number of Sequences: 37866
Number of extensions: 942787
Number of successful extensions: 5104
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 200
Number of HSP's successfully gapped in prelim test: 192
Number of HSP's that attempted gapping in prelim test: 3466
Number of HSP's gapped (non-prelim): 1358
length of query: 304
length of database: 18,247,518
effective HSP length: 102
effective length of query: 202
effective length of database: 14,385,186
effective search space: 2905807572
effective search space used: 2905807572
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.