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Search of human proteins with 19923629
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]
(508 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923629 Fc receptor-like 2 precursor [Homo sapiens] 1016 0.0
gi|21314764 Fc receptor-like 3 precursor [Homo sapiens] 457 e-128
gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens] 436 e-122
gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens] 436 e-122
gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens] 379 e-105
gi|157694526 Fc receptor-like 5 [Homo sapiens] 293 2e-79
gi|14550416 Fc receptor-like 4 precursor [Homo sapiens] 276 2e-74
gi|157057547 Fc receptor-like 6 [Homo sapiens] 137 2e-32
gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens] 113 4e-25
gi|50878302 Fc receptor-like B [Homo sapiens] 100 3e-21
gi|10835133 Fc fragment of IgG, high affinity Ia, receptor (CD64... 96 6e-20
gi|110347451 platelet/endothelial cell adhesion molecule [Homo s... 78 2e-14
gi|13489095 sialoadhesin precursor [Homo sapiens] 77 5e-14
gi|110349719 titin isoform N2-A [Homo sapiens] 75 2e-13
gi|45594240 limbic system-associated membrane protein [Homo sapi... 72 2e-12
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 69 8e-12
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 69 8e-12
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 69 8e-12
gi|15147240 brother of CDO [Homo sapiens] 69 8e-12
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 69 1e-11
gi|157819143 IgLON family member 5 [Homo sapiens] 66 7e-11
gi|156564378 carcinoembryonic antigen-related cell adhesion mole... 66 9e-11
gi|156564393 carcinoembryonic antigen-related cell adhesion mole... 65 1e-10
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 65 2e-10
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 65 2e-10
gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo... 62 9e-10
gi|142976733 surface glycoprotein, Ig superfamily member [Homo s... 61 3e-09
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 60 5e-09
gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens] 60 6e-09
gi|146229333 hypothetical protein LOC284021 [Homo sapiens] 59 1e-08
>gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]
Length = 508
Score = 1016 bits (2627), Expect = 0.0
Identities = 508/508 (100%), Positives = 508/508 (100%)
Query: 1 MLLWSLLVIFDAVTEQADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSV 60
MLLWSLLVIFDAVTEQADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSV
Sbjct: 1 MLLWSLLVIFDAVTEQADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSV 60
Query: 61 FKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIE 120
FKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIE
Sbjct: 61 FKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIE 120
Query: 121 GGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAE 180
GGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAE
Sbjct: 121 GGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAE 180
Query: 181 TVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWY 240
TVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWY
Sbjct: 181 TVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWY 240
Query: 241 REATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRP 300
REATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRP
Sbjct: 241 REATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRP 300
Query: 301 VLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTA 360
VLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTA
Sbjct: 301 VLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTA 360
Query: 361 EHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLLYA 420
EHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLLYA
Sbjct: 361 EHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLLYA 420
Query: 421 LFHKISGESSATNEPRGASRPNPQEFTYSSPTPDMEELQPVYVNVGSVDVDVVYSQVWSM 480
LFHKISGESSATNEPRGASRPNPQEFTYSSPTPDMEELQPVYVNVGSVDVDVVYSQVWSM
Sbjct: 421 LFHKISGESSATNEPRGASRPNPQEFTYSSPTPDMEELQPVYVNVGSVDVDVVYSQVWSM 480
Query: 481 QQPESSANIRTLLENKDSQVIYSSVKKS 508
QQPESSANIRTLLENKDSQVIYSSVKKS
Sbjct: 481 QQPESSANIRTLLENKDSQVIYSSVKKS 508
>gi|21314764 Fc receptor-like 3 precursor [Homo sapiens]
Length = 734
Score = 457 bits (1175), Expect = e-128
Identities = 227/374 (60%), Positives = 280/374 (74%), Gaps = 3/374 (0%)
Query: 18 DSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSDS 77
D L L A VFEGD+++L+CQG+ N + Y+KD K+L + S V D+
Sbjct: 100 DWLILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNS-VSRDN 158
Query: 78 GNYFCSTKGQLFLWD--KTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQ 135
Y C+ + ++ D TS + I+VQELF PVL ASS PIEG P++L CET+LSPQ
Sbjct: 159 SKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQ 218
Query: 136 RLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQI 195
R DVQLQF FR++Q LG GWS SP LQI A+W+ED+GSYWC+ ETVTH I+K+SL+SQI
Sbjct: 219 RPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQI 278
Query: 196 HVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRS 255
VQR+P+SNV+LEIR GGQ+ EG+ ++L+CSVA G+G VTFSW++E S+G+KTQRS
Sbjct: 279 RVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRS 338
Query: 256 LSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGD 315
L AEL + VKESDAG+YYC ADN H PI S + + VRIPVS PVLT R+P A VGD
Sbjct: 339 LLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGD 398
Query: 316 LLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLG 375
LLELHCE+LRGSPPILY+FYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSC+A+NGLG
Sbjct: 399 LLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLG 458
Query: 376 AQCSEAVPVSISGP 389
AQ S V + ++ P
Sbjct: 459 AQHSHGVSLRVTVP 472
Score = 263 bits (672), Expect = 3e-70
Identities = 192/510 (37%), Positives = 271/510 (53%), Gaps = 37/510 (7%)
Query: 26 SSVFEGDSIVLKCQGE---QNWKIQ-KMAYHKDNKELSV-FKKFSDFLIQSAVLSDSGNY 80
S+ EG + L C+ + Q +Q + + +D++ L + + + I + DSG+Y
Sbjct: 199 STPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSY 258
Query: 81 FCSTKGQLFLWDKTSNIVKIKVQELFQRPV---LTASSFQPIEGGPVSLKCETRLSPQRL 137
+C + K S +I+VQ + V + + Q IEG + L C S +
Sbjct: 259 WCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLIC----SVAQG 314
Query: 138 DVQLQFCFFRENQVLGSGWSSS----PELQISAVWSEDTGSYWCKAETVTHRIRKQSLQS 193
+ F + +E +V G + EL + V D G Y+C A+ V I ++
Sbjct: 315 SGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRV 374
Query: 194 QIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQ 253
+ RIP+S+ L RAP G L L C G+ + + +Y E ++G +
Sbjct: 375 TV---RIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHE--DVTLGNSSA 429
Query: 254 RSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAV 313
S ++ +G Y C ADNG S V++ V +PVSRPVLTLR+PGAQA V
Sbjct: 430 PSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVV 489
Query: 314 GDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNG 373
GDLLELHCE+LRGS PILY FYHED TLGN SA SGGGASFNLSLT EHSGNYSCEA+NG
Sbjct: 490 GDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTEHSGNYSCEADNG 549
Query: 374 LGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLL-YALFHKISGESSAT 432
LGAQ S+ V ++++G R L AG+ + +L A LL YA + G SAT
Sbjct: 550 LGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLAAAAALLHYARARRKPGGLSAT 609
Query: 433 ----------NEPRGA--SRPNPQEFTYSSPTPDMEELQPVYVNVGSVDVDVVYSQVWSM 480
EP + SR +PQE T+S P M EL+P+Y NV D + +YSQ+WS+
Sbjct: 610 GTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPM-ELEPMYSNVNPGDSNPIYSQIWSI 668
Query: 481 QQ-PESSANIRTL-LENKDSQVIYSSVKKS 508
Q E+SAN + E+++ V+YS +KK+
Sbjct: 669 QHTKENSANCPMMHQEHEELTVLYSELKKT 698
Score = 82.8 bits (203), Expect = 7e-16
Identities = 95/390 (24%), Positives = 168/390 (43%), Gaps = 46/390 (11%)
Query: 1 MLLWSLLVIFDAVTEQAD----SLTLVAP--SSVFEGDSIVLKCQGEQNWKIQKMAYHKD 54
MLLW LL+I EQ+ ++ L+ P S+ F+G+ + L C + Q Y
Sbjct: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
Query: 55 NKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
+++L K +++ GNY C T+G S+ V ++ F L
Sbjct: 61 DEKLLKIKH------DKIQITEPGNYQCKTRG-----SSLSDAVHVE----FSPDWLILQ 105
Query: 115 SFQPI-EGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTG 173
+ P+ EG V L+C+ + + Q ++++ + L + ++ ++ +++V S D
Sbjct: 106 ALHPVFEGDNVILRCQGKDNKN----THQKVYYKDGKQLPNSYNLE-KITVNSV-SRDNS 159
Query: 174 SYWCKAETVTH--RIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLC----S 227
Y C A + I S I VQ + + V +RA EG + L C S
Sbjct: 160 KYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPV---LRASSSTPIEGSPMTLTCETQLS 216
Query: 228 VAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSK 287
+ FS +R++ +G S S L+IPA+ D+G Y+C + I+ +
Sbjct: 217 PQRPDVQLQFSLFRDSQTLGLG----WSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKR 272
Query: 288 VVNIPV---RIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHED--VTLG 342
+ + R+PVS L +R G Q G+ + L C +GS + + ++ E +LG
Sbjct: 273 SLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLG 332
Query: 343 NSSAPSGGGASFNLSLTAEHSGNYSCEANN 372
+ S L++ +G Y C A+N
Sbjct: 333 RKTQRSLLAELHVLTVKESDAGRYYCAADN 362
>gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]
Length = 429
Score = 436 bits (1122), Expect = e-122
Identities = 234/403 (58%), Positives = 293/403 (72%), Gaps = 10/403 (2%)
Query: 111 LTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSE 170
L AS P EG PV+L C+ Q D Q QFCFFR+ + LG GWSSSP+LQI+A+W E
Sbjct: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
Query: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230
DTGSYWC+A+T+ ++ + S +SQI+V R+P+++VSLE + PGGQV EG +L+L+CSVA
Sbjct: 80 DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
Query: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290
GTG++TF WY+ A G ++ KTQRSL+AE EIP+V+ESDA +YYC A+NG+ P S +V+
Sbjct: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
Query: 291 IPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGG 350
I VRIPVSRP+L LR+P AQAAV D+LELHCEALRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
Query: 351 GASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLG 410
GASFNLSLT EHSGNYSCEANNGLGAQ SEAV ++ + P G R + +T+GV+ GL LG
Sbjct: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLG 318
Query: 411 FTGVALLL-YALFHKISGESSATNEPRGASRPNPQEFTY-SSPTPDMEELQPVYVNVGSV 468
VALL Y L KI G SA + R P PQEFTY +SPTP +LQP+Y NV V
Sbjct: 319 PATVALLFCYGLKRKI-GRRSARDPLRSLPSPLPQEFTYLNSPTPG--QLQPIYENVNVV 375
Query: 469 DVDVVYSQVWSMQQPESSANIRTL---LENKDSQVIYSSVKKS 508
D VYS + Q + S TL +E+K S IYS ++K+
Sbjct: 376 SGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKA 418
Score = 54.3 bits (129), Expect = 3e-07
Identities = 72/306 (23%), Positives = 122/306 (39%), Gaps = 19/306 (6%)
Query: 1 MLLWSLLVIFDAVTEQADSLTLVAPSSVFEGDSIVLKCQGE--QNWKIQ-KMAYHKDNKE 57
ML LL+I + E A+ + +PS EG + L C+ Q+ Q + + +D +
Sbjct: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
Query: 58 LSVFKKFSDFL-IQSAVLSDSGNYFC--STKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
L S L I + D+G+Y+C T L + S I +V
Sbjct: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
Query: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRE----NQVLGSGWSSSPELQISAVWSE 170
Q +EG + L C + + F +++ N + S + E +I +V
Sbjct: 121 GGQVMEGDRLVLICSVAMGTG----DITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRES 176
Query: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230
D Y+C AE + + RIP+S L +RAP Q L L C
Sbjct: 177 DAEQYYCVAENGYGPSPSGLVSITV---RIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
Query: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290
G+ + + +Y E ++G ++ S ++ E +G Y C A+NG +S+ V
Sbjct: 234 GSPPILYWFYHE--DITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
Query: 291 IPVRIP 296
+ +P
Sbjct: 292 LNFTVP 297
>gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]
Length = 428
Score = 436 bits (1121), Expect = e-122
Identities = 235/403 (58%), Positives = 294/403 (72%), Gaps = 11/403 (2%)
Query: 111 LTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSE 170
L AS P EG PV+L C+ Q D Q QFCFFR+ + LG GWSSSP+LQI+A+W E
Sbjct: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
Query: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230
DTGSYWC+A+T+ ++ + S +SQI+V R+P+++VSLE + PGGQV EG +L+L+CSVA
Sbjct: 80 DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
Query: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290
GTG++TF WY+ A G ++ KTQRSL+AE EIP+V+ESDA +YYC A+NG+ P S +V+
Sbjct: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
Query: 291 IPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGG 350
I VRIPVSRP+L LR+P AQAAV D+LELHCEALRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
Query: 351 GASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLG 410
GASFNLSLT EHSGNYSCEANNGLGAQ SEAV ++ + P G R + +T+GV+ GL LG
Sbjct: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLG 318
Query: 411 FTGVALLL-YALFHKISGESSATNEPRGASRPNPQEFTY-SSPTPDMEELQPVYVNVGSV 468
VALL Y L KI G SA + R P PQEFTY +SPTP +LQP+Y NV V
Sbjct: 319 PATVALLFCYGLKRKI-GRRSARDPLRSLPSPLPQEFTYLNSPTPG--QLQPIYENVNVV 375
Query: 469 DVDVVYSQVWSMQQPESSANIRTL---LENKDSQVIYSSVKKS 508
D VYS + QPE + TL +E+K S IYS ++K+
Sbjct: 376 SGDEVYSLAY-YNQPEQESVAETLGTHMEDKVSLDIYSRLRKA 417
Score = 54.3 bits (129), Expect = 3e-07
Identities = 72/306 (23%), Positives = 122/306 (39%), Gaps = 19/306 (6%)
Query: 1 MLLWSLLVIFDAVTEQADSLTLVAPSSVFEGDSIVLKCQGE--QNWKIQ-KMAYHKDNKE 57
ML LL+I + E A+ + +PS EG + L C+ Q+ Q + + +D +
Sbjct: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
Query: 58 LSVFKKFSDFL-IQSAVLSDSGNYFC--STKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
L S L I + D+G+Y+C T L + S I +V
Sbjct: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
Query: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRE----NQVLGSGWSSSPELQISAVWSE 170
Q +EG + L C + + F +++ N + S + E +I +V
Sbjct: 121 GGQVMEGDRLVLICSVAMGTG----DITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRES 176
Query: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230
D Y+C AE + + RIP+S L +RAP Q L L C
Sbjct: 177 DAEQYYCVAENGYGPSPSGLVSITV---RIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
Query: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290
G+ + + +Y E ++G ++ S ++ E +G Y C A+NG +S+ V
Sbjct: 234 GSPPILYWFYHE--DITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
Query: 291 IPVRIP 296
+ +P
Sbjct: 292 LNFTVP 297
>gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens]
Length = 366
Score = 379 bits (974), Expect = e-105
Identities = 202/355 (56%), Positives = 247/355 (69%), Gaps = 44/355 (12%)
Query: 111 LTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSE 170
L AS P EG PV+L C+ Q D Q QFCFFR+ + LG GWSSSP+LQI+A+W E
Sbjct: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
Query: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230
DTGSYWC+A+T+ ++ + S +SQI+V R+P+++VSLE + PGGQV EG +L+L+CSVA
Sbjct: 80 DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
Query: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290
GTG++TF WY+ A G ++ KTQRSL+AE EIP+V+ESDA +YYC A+NG+ P S +V+
Sbjct: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
Query: 291 IPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGG 350
I VRIPVSRP+L LR+P AQAAV D+LELHCEALRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
Query: 351 GASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLG 410
GASFNLSLT EHSGNYSCEANNGLGAQ SEAV L
Sbjct: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAV-------------------------TLN 293
Query: 411 FTGVALLLYALFHKISGESSATNEPRGASRPNPQEFTY-SSPTPDMEELQPVYVN 464
FT G SA + R P PQEFTY +SPTP +LQP+Y N
Sbjct: 294 FT--------------GRRSARDPLRSLPSPLPQEFTYLNSPTPG--QLQPIYEN 332
Score = 53.9 bits (128), Expect = 3e-07
Identities = 77/319 (24%), Positives = 127/319 (39%), Gaps = 21/319 (6%)
Query: 1 MLLWSLLVIFDAVTEQADSLTLVAPSSVFEGDSIVLKCQGE--QNWKIQ-KMAYHKDNKE 57
ML LL+I + E A+ + +PS EG + L C+ Q+ Q + + +D +
Sbjct: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
Query: 58 LSVFKKFSDFL-IQSAVLSDSGNYFC--STKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
L S L I + D+G+Y+C T L + S I +V
Sbjct: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
Query: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRE----NQVLGSGWSSSPELQISAVWSE 170
Q +EG + L C + + F +++ N + S + E +I +V
Sbjct: 121 GGQVMEGDRLVLICSVAMGTG----DITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRES 176
Query: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230
D Y+C AE + + RIP+S L +RAP Q L L C
Sbjct: 177 DAEQYYCVAENGYGPSPSGLVSITV---RIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
Query: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVV- 289
G+ + + +Y E ++G ++ S ++ E +G Y C A+NG +S+ V
Sbjct: 234 GSPPILYWFYHE--DITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
Query: 290 -NIPVRIPVSRPVLTLRSP 307
N R P+ +L SP
Sbjct: 292 LNFTGRRSARDPLRSLPSP 310
>gi|157694526 Fc receptor-like 5 [Homo sapiens]
Length = 977
Score = 293 bits (751), Expect = 2e-79
Identities = 172/371 (46%), Positives = 221/371 (59%), Gaps = 5/371 (1%)
Query: 19 SLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSDSG 78
SL L AP SVFEGDS+VL+C+ + + Y DN L+ K +DF I A L D+G
Sbjct: 104 SLILQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKNDNV-LAFLNKRTDFHIPHACLKDNG 162
Query: 79 NYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLD 138
Y C T + +SN VKI+VQE F RPVL ASSFQPI G PV+L CET+LS +R D
Sbjct: 163 AYRC-TGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSD 221
Query: 139 VQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQ 198
V L+F FFR++Q LG GWS SP QI+A+WS+D+G YWCKA T+ + + S +S I VQ
Sbjct: 222 VPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQ 281
Query: 199 RIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSA 258
IP S+ L + EG K+ L C + + +Y E G + K+ R
Sbjct: 282 -IPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHE--GVPLRHKSVRCERG 338
Query: 259 ELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLE 318
++ ++G YYC ADNG SK V++ V +PVS PVL L SP G +
Sbjct: 339 ASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVT 398
Query: 319 LHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQC 378
LHCEA RGS PILYQF+HE L SA S GG + + SLTAEHSGNY C A+NG G Q
Sbjct: 399 LHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQR 458
Query: 379 SEAVPVSISGP 389
S+AV +S++ P
Sbjct: 459 SKAVSLSVTVP 469
Score = 275 bits (703), Expect = 7e-74
Identities = 197/499 (39%), Positives = 265/499 (53%), Gaps = 36/499 (7%)
Query: 24 APSSVFEGDSIVLKCQGEQNW-KIQKMAYHKD-----NKELSVFKKFSDFLIQSAVLSDS 77
A + FEG ++ L C+ ++ +I YH+D + SV + F S S
Sbjct: 480 AEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSF---SLTEGHS 536
Query: 78 GNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLT--ASSFQPIEGGPVSLKCET-RLSP 134
GNY+C+ + S +V + V RP+LT Q + G + L CE R SP
Sbjct: 537 GNYYCTADNGF--GPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSP 594
Query: 135 QRLDVQLQFCFFRENQVLGS-----GWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQ 189
L + F+ E+ LGS G +S L ++A E +G+Y C+A
Sbjct: 595 PIL-----YWFYHEDVTLGSSSAPSGGEASFNLSLTA---EHSGNYSCEANNGLVAQHSD 646
Query: 190 SLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMG 249
++ + V P+S L RAP Q G L L C G+ + + +Y E ++G
Sbjct: 647 TISLSVIV---PVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHE--DVTLG 701
Query: 250 KKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGA 309
K + S ++ +G Y C ADNG +S++V + V +PVSRPVLTLR+PG
Sbjct: 702 KISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGT 761
Query: 310 QAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCE 369
AAVGDLLELHCEALRGSP ILY+F+HEDVTLGN S+PSGG AS NLSLTAEHSGNYSCE
Sbjct: 762 HAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPSGG-ASLNLSLTAEHSGNYSCE 820
Query: 370 ANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLLYALFHKISGES 429
A+NGLGAQ SE V + I+G R GV GL + G ALLLY + +G
Sbjct: 821 ADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGLLSIAGLAAGALLLYCWLSRKAGRK 880
Query: 430 SATNEPRGASRPNPQEFTYSSPTPDMEELQPVYVNVGSVDVDVVYSQVWSMQQPE--SSA 487
A++ R S + QE TY + P EELQPVY N +VVYS+V +Q+ + + A
Sbjct: 881 PASDPARSPSDSDSQEPTYHN-VPAWEELQPVYTNANPRGENVVYSEVRIIQEKKKHAVA 939
Query: 488 NIRTLLENKDSQVIYSSVK 506
+ L NK S +IYS VK
Sbjct: 940 SDPRHLRNKGSPIIYSEVK 958
Score = 226 bits (576), Expect = 4e-59
Identities = 147/368 (39%), Positives = 207/368 (56%), Gaps = 18/368 (4%)
Query: 29 FEGDSIVLKCQGEQNWKIQKMAYHKDNKEL---SVFKKFSDFLIQSAVLSDSGNYFCSTK 85
FEG + L C+ +++ ++ + L SV + + S +SGNY+C+
Sbjct: 299 FEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTAD 358
Query: 86 GQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPI--EGGPVSLKCETRLSPQRLDVQLQF 143
L K S V + V PVL SS + + EG V+L CE QR + + +
Sbjct: 359 NGLGA--KPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEA----QRGSLPILY 412
Query: 144 CFFRENQVLGS-GWSSSPELQIS-AVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIP 201
F E L +S+ + IS ++ +E +G+Y+C A+ R +++ + V P
Sbjct: 413 QFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTV---P 469
Query: 202 ISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELE 261
+S+ L + + EG + L C V G+ + + +Y E + + S+
Sbjct: 470 VSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHE--DMPLWSSSTPSVGRVSF 527
Query: 262 IPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHC 321
++ E +G YYC ADNG P +S+VV++ V +PVSRP+LTLR P AQA VGDLLELHC
Sbjct: 528 SFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHC 587
Query: 322 EALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEA 381
EA RGSPPILY FYHEDVTLG+SSAPSGG ASFNLSLTAEHSGNYSCEANNGL AQ S+
Sbjct: 588 EAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDT 647
Query: 382 VPVSISGP 389
+ +S+ P
Sbjct: 648 ISLSVIVP 655
Score = 218 bits (556), Expect = 8e-57
Identities = 162/437 (37%), Positives = 220/437 (50%), Gaps = 31/437 (7%)
Query: 20 LTLVAPSS-VFEGDSIVLKCQGEQNWKIQKMAYHKDNKEL---SVFKKFSDFLIQSAVLS 75
L L +P +FEG + L C+ ++ +H + L S + S
Sbjct: 382 LNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAE 441
Query: 76 DSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPI--EGGPVSLKCETRLS 133
SGNY+C+ + S V + V PVLT SS + + EG V+L CE
Sbjct: 442 HSGNYYCTADNGF--GPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEV--- 496
Query: 134 PQRLDVQLQFCFFRENQVLGSGWSSSPEL-QISAVWS---EDTGSYWCKAETVTHRIRKQ 189
QR Q+ + F+ E+ L S SS+P + ++S +S +G+Y+C A+ R +
Sbjct: 497 -QRGSPQILYQFYHEDMPLWS--SSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSE 553
Query: 190 SLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYRE-ATGTSM 248
+ + V P+S L +R P Q G L L C G+ + + +Y E T S
Sbjct: 554 VVSLFVTV---PVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSS 610
Query: 249 GKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPG 308
+ S L + A +G Y C A+NG V S +++ V +PVSRP+LT R+P
Sbjct: 611 SAPSGGEASFNLSLTA---EHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPR 667
Query: 309 AQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSC 368
AQA VGDLLELHCEALRGS PILY FYHEDVTLG SAPSGGGASFNLSLT EHSG YSC
Sbjct: 668 AQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSC 727
Query: 369 EANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVL------GFTGVALLLYALF 422
EA+NGL AQ SE V + ++ P + A G L G L+LY F
Sbjct: 728 EADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFF 787
Query: 423 HKISGESSATNEPRGAS 439
H+ + ++ GAS
Sbjct: 788 HEDVTLGNRSSPSGGAS 804
Score = 126 bits (316), Expect = 5e-29
Identities = 115/401 (28%), Positives = 184/401 (45%), Gaps = 37/401 (9%)
Query: 1 MLLWSLLVIFDAVTEQ-----ADSLTLVAP-SSVFEGDSIVLKCQGEQNWKIQKMAYHKD 54
MLLW +L++ V+ Q + L P ++VF+G+ + L C+G + + QK ++
Sbjct: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
Query: 55 NKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
+ ++ D +++ + +SG Y C +G S+ V + + ++ +
Sbjct: 61 YLGKEILRETPDNILE---VQESGEYRCQAQG-----SPLSSPVHL---DFSSASLILQA 109
Query: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGS 174
EG V L+C + +V L ++ + VL + + + I +D G+
Sbjct: 110 PLSVFEGDSVVLRCRA-----KAEVTLNNTIYKNDNVL-AFLNKRTDFHIPHACLKDNGA 163
Query: 175 YWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLC----SVAG 230
Y C + S +I VQ P + L RA Q G + L C S+
Sbjct: 164 YRCTGYKES-CCPVSSNTVKIQVQE-PFTRPVL--RASSFQPISGNPVTLTCETQLSLER 219
Query: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290
+ F ++R+ +G SLS +I A+ D+G Y+C+A + S
Sbjct: 220 SDVPLRFRFFRDDQTLGLG----WSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPR 275
Query: 291 --IPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPS 348
I V+IP S PVLTL A G + LHCE S LY+FYHE V L + S
Sbjct: 276 SWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRC 335
Query: 349 GGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGP 389
GAS + SLT E+SGNY C A+NGLGA+ S+AV +S++ P
Sbjct: 336 ERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVP 376
>gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]
Length = 515
Score = 276 bits (707), Expect = 2e-74
Identities = 152/305 (49%), Positives = 195/305 (63%), Gaps = 13/305 (4%)
Query: 17 ADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSD 76
+DSL L AP SVFEGD++VL+C + K+ + Y + LS+ K D LI A ++
Sbjct: 102 SDSLILQAPYSVFEGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNN 161
Query: 77 SGNYFCSTKGQ---LFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLS 133
+GNY C G +F SN IK+QELF P L A+ QP EG V+L CET+L
Sbjct: 162 NGNYRCIGYGDENDVF----RSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLP 217
Query: 134 PQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQS 193
P+R D L F FFR+ +V+ S WS+ PELQ+ VW E++GSYWC AETV I K S
Sbjct: 218 PERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSL 277
Query: 194 QIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQ 253
QIHVQRIP+S V LE + GGQ EG+ L+L+CSVA GTG+ TFSW+RE S+G+KTQ
Sbjct: 278 QIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQ 337
Query: 254 RSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVR-IPVSRPVLTLRSPGAQAA 312
RSL AELE+PA+++S AG YYC ADN + P+QS V+N+ VR P +R L A A
Sbjct: 338 RSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLV-----AAGA 392
Query: 313 VGDLL 317
G LL
Sbjct: 393 TGGLL 397
Score = 138 bits (347), Expect = 1e-32
Identities = 143/527 (27%), Positives = 236/527 (44%), Gaps = 51/527 (9%)
Query: 1 MLLWSLLVIFDAVTEQADS-----LTLVAP-SSVFEGDSIVLKCQGEQNWKIQKMA-YHK 53
MLLW+ L+ F V Q+ + +++ P ++ F+G+ + L C G Q + +K YH+
Sbjct: 1 MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
Query: 54 D--NKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVL 111
++L++ + + +SG Y C +G SN V++ LF L
Sbjct: 61 HYWGEKLTLTPG------NTLEVRESGLYRCQARGS-----PRSNPVRL----LFSSDSL 105
Query: 112 TASS-FQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSE 170
+ + EG + L+C R + V+ + N + S + S +L I S
Sbjct: 106 ILQAPYSVFEGDTLVLRCHRRRKEKLTAVKYTW-----NGNILSISNKSWDLLIPQASSN 160
Query: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVA- 229
+ G+Y C + + +S + +I E++A Q TEG + L C
Sbjct: 161 NNGNYRC----IGYGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQL 216
Query: 230 ---GGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADN--GHVPI 284
+ F+++R+ T EL++P V ++G Y+C A+ G++
Sbjct: 217 PPERSDTPLHFNFFRDGEVILSDWSTY----PELQLPTVWRENSGSYWCGAETVRGNIHK 272
Query: 285 QSKVVNIPV-RIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDV--TL 341
S + I V RIPVS +L + G QA G++L L C G+ + ++ ED+ +L
Sbjct: 273 HSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESL 332
Query: 342 GNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGV 401
G + S ++ H+G Y C A+N G S + V++ G R L+ AG
Sbjct: 333 GRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGA 392
Query: 402 LWGLFGVLGFTGVALLLYALFHKISGESSATNEPRGASRPNPQEFTYSSPTPDMEELQPV 461
GL L VALL + + SG +E R P P E ++S P ELQ +
Sbjct: 393 TGGLLSAL-LLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSI-CPAQVELQSL 450
Query: 462 YVNVGSVDVDVVYSQVWSMQ--QPESSANIRTLLENKDSQVIYSSVK 506
YV+V D+VYS++ + Q + E + RTLLE+KD V+YS VK
Sbjct: 451 YVDVHPKKGDLVYSEIQTTQLGEEEEANTSRTLLEDKDVSVVYSEVK 497
>gi|157057547 Fc receptor-like 6 [Homo sapiens]
Length = 434
Score = 137 bits (346), Expect = 2e-32
Identities = 124/406 (30%), Positives = 178/406 (43%), Gaps = 52/406 (12%)
Query: 120 EGGPVSLKCE----TRLSPQRLDVQLQFCFF-RENQVLGSGWSSSPELQISAVWSEDTGS 174
EG ++L+C+ T LS + +F F +ENQ L G A + G
Sbjct: 31 EGDALTLRCQGWKNTPLSQVKFYRDGKFLHFSKENQTLSMG----------AATVQSRGQ 80
Query: 175 YWCKAET--VTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVA--- 229
Y C + + + S + + VQ + V I +P + EG + L C
Sbjct: 81 YSCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSP--EPREGSLVTLRCQTKLHP 138
Query: 230 -GGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRA--DNGHVPIQS 286
+ FS++++ R EL IP KE D+G Y+C + G V QS
Sbjct: 139 LRSALRLLFSFHKDGHTLQ-----DRGPHPELCIPGAKEGDSGLYWCEVAPEGGQVQKQS 193
Query: 287 KVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSA 346
+ + V+ PVSRPVLTL A AVGD+++L CEA RGSPPILY FY ++ +GN SA
Sbjct: 194 PQLEVRVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGNHSA 253
Query: 347 PSGGGASFNLSLTAEH-SGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGL 405
P GG S + +E +GNYSCEA N + + SE +S+ G V W
Sbjct: 254 PCGGTTSLLFPVKSEQDAGNYSCEAENSVSRERSEPKKLSLKGSQVLFTPASNWLVPWLP 313
Query: 406 FGVLGF--TGVALLLYALFHKISGESSATNEPRGASRPNPQEFTYSSPTPDMEELQPVYV 463
+LG ALL+Y + +G P P + PT E P+Y
Sbjct: 314 ASLLGLMVIAAALLVYVRSWRKAG-------------PLPSQI---PPTAPGGEQCPLYA 357
Query: 464 NV---GSVDVDVVYSQVWSMQQPESSANIRTLLENKDSQVIYSSVK 506
NV D VVYS V + + + + KDS +I + V+
Sbjct: 358 NVHHQKGKDEGVVYSVVHRTSKRSEARSAEFTVGRKDSSIICAEVR 403
Score = 134 bits (338), Expect = 1e-31
Identities = 91/285 (31%), Positives = 143/285 (50%), Gaps = 11/285 (3%)
Query: 1 MLLWSLLVIFDAVTEQADSLTLVA-PSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELS 59
MLLW+ +++F + L L A P+ VFEGD++ L+CQG +N + ++ +++D K L
Sbjct: 1 MLLWTAVLLFVPCVGKTVWLYLQAWPNPVFEGDALTLRCQGWKNTPLSQVKFYRDGKFLH 60
Query: 60 VFKKFSDFLIQSAVLSDSGNYFCSTKGQLF----LWDKTSNIVKIKVQELFQRPVLTA-S 114
K+ + +A + G Y CS GQ+ + +TS ++VQELF PVL+A
Sbjct: 61 FSKENQTLSMGAATVQSRGQYSCS--GQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIP 118
Query: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGS 174
S +P EG V+L+C+T+L P R ++L F F ++ L PEL I D+G
Sbjct: 119 SPEPREGSLVTLRCQTKLHPLRSALRLLFSFHKDGHTL-QDRGPHPELCIPGAKEGDSGL 177
Query: 175 YWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGN 234
YWC+ +++KQS Q ++ VQ P+S L + G + LLC G+
Sbjct: 178 YWCEVAPEGGQVQKQSPQLEVRVQ-APVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPP 236
Query: 235 VTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADN 279
+ +S+Y + + L P E DAG Y C A+N
Sbjct: 237 ILYSFYLDEKIVG-NHSAPCGGTTSLLFPVKSEQDAGNYSCEAEN 280
>gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens]
Length = 376
Score = 113 bits (283), Expect = 4e-25
Identities = 70/187 (37%), Positives = 108/187 (57%), Gaps = 9/187 (4%)
Query: 18 DSLTLVAPSS-VFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSD 76
D L L P+ VFEGD +VL+CQ Q+W + ++ +++D L +F I +D
Sbjct: 95 DWLILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRDGSALGPPGPNREFSITVVQKAD 154
Query: 77 SGNYFCS----TKGQLFLWDKTSNIVKIKVQELFQRPVLTA-SSFQPIEGGPVSLKCETR 131
SG+Y CS + G +T+++V I VQELF P+L A S +P G P++L C+T+
Sbjct: 155 SGHYHCSGIFQSPGPGI--PETASVVAITVQELFPAPILRAVPSAEPQAGSPMTLSCQTK 212
Query: 132 LSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSL 191
L QR +L F F+++ +++ S SS E QI + +GSYWC+A T +++ KQS
Sbjct: 213 LPLQRSAARLLFSFYKDGRIVQSRGLSS-EFQIPTASEDHSGSYWCEAATEDNQVWKQSP 271
Query: 192 QSQIHVQ 198
Q +I VQ
Sbjct: 272 QLEIRVQ 278
Score = 52.8 bits (125), Expect = 7e-07
Identities = 46/173 (26%), Positives = 78/173 (45%), Gaps = 19/173 (10%)
Query: 207 LEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVK 266
L ++ P V EG L+L C ++YR+ G+++G + E I V+
Sbjct: 97 LILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRD--GSALGPPGP---NREFSITVVQ 151
Query: 267 ESDAGKYYC----RADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCE 322
++D+G Y+C ++ +P + VV I V+ P+L P A+ G + L C+
Sbjct: 152 KADSGHYHCSGIFQSPGPGIPETASVVAITVQELFPAPILRA-VPSAEPQAGSPMTLSCQ 210
Query: 323 AL----RGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAE-HSGNYSCEA 370
R + +L+ FY + G G + F + +E HSG+Y CEA
Sbjct: 211 TKLPLQRSAARLLFSFYKD----GRIVQSRGLSSEFQIPTASEDHSGSYWCEA 259
Score = 40.8 bits (94), Expect = 0.003
Identities = 41/162 (25%), Positives = 70/162 (43%), Gaps = 18/162 (11%)
Query: 142 QFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKA--ETVTHRIRKQSLQSQIHVQR 199
Q F+R+ LG + E I+ V D+G Y C ++ I + + I VQ
Sbjct: 126 QVTFYRDGSALGPP-GPNREFSITVVQKADSGHYHCSGIFQSPGPGIPETASVVAITVQE 184
Query: 200 IPISNVSLEIRAPGGQVTEGQKLILLCS----VAGGTGNVTFSWYREATGTSMGKKTQ-R 254
+ + + + P + G + L C + + FS+Y++ G+ Q R
Sbjct: 185 LFPAPILRAV--PSAEPQAGSPMTLSCQTKLPLQRSAARLLFSFYKD------GRIVQSR 236
Query: 255 SLSAELEIPAVKESDAGKYYCRA--DNGHVPIQSKVVNIPVR 294
LS+E +IP E +G Y+C A ++ V QS + I V+
Sbjct: 237 GLSSEFQIPTASEDHSGSYWCEAATEDNQVWKQSPQLEIRVQ 278
Score = 38.1 bits (87), Expect = 0.019
Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 5/78 (6%)
Query: 292 PVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGG 351
P + VS L L+ P GDLL L C+A + P FY + LG P G
Sbjct: 87 PFHLIVSYDWLILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRDGSALG----PPGPN 142
Query: 352 ASFNLSLTAE-HSGNYSC 368
F++++ + SG+Y C
Sbjct: 143 REFSITVVQKADSGHYHC 160
>gi|50878302 Fc receptor-like B [Homo sapiens]
Length = 426
Score = 100 bits (249), Expect = 3e-21
Identities = 78/265 (29%), Positives = 123/265 (46%), Gaps = 20/265 (7%)
Query: 18 DSLTLVAP-SSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSD 76
D L L P + VFEG+ +VL+C+G + + K+ Y+ D + + F +++ + A SD
Sbjct: 103 DWLILQVPYAPVFEGEPLVLRCRGWYDKVVYKLHYYHDGQAVRYFHSSANYTVLQARASD 162
Query: 77 SGNYFCSTKGQLFLWDKT--SNIVKIKVQELFQRPVLTASSFQPIEG---GPVSLKCETR 131
SG Y CS ++ + S V + VQELF+ PVL + G G V L+C+TR
Sbjct: 163 SGRYQCSGTMRIPVESAPMFSAKVAVTVQELFRAPVLRVMGPREARGAALGGVVLRCDTR 222
Query: 132 LSPQRLDVQLQFCFFRENQ-VLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQS 190
L PQ+ D LQF F++ ++ V W + E + E+ SYWC+A T T +RK+S
Sbjct: 223 LHPQKRDTPLQFAFYKYSRAVRRFDWGA--EYTVPEPEVEELESYWCEAATATRSVRKRS 280
Query: 191 LQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGK 250
Q+ P+ S AP ++A G ++F + +
Sbjct: 281 PWLQLPGPGSPLDPASTTAPAPWA-----------AALAPGNRPLSFRKPPVSRSVPLVT 329
Query: 251 KTQRSLSAELEIPAVKESDAGKYYC 275
+ + S L+ PA AG C
Sbjct: 330 SVRNTTSTGLQFPASGAPTAGPPAC 354
Score = 34.7 bits (78), Expect = 0.21
Identities = 55/226 (24%), Positives = 90/226 (39%), Gaps = 34/226 (15%)
Query: 120 EGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKA 179
+G V+LKC+ P L++Q + +L S E+Q V Y C+
Sbjct: 36 KGERVTLKCDG-YHPLLLELQPISTLWYLGHLLLPSHKKSIEVQTPGV-------YRCQT 87
Query: 180 ETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSW 239
R + IH+ +SN L ++ P V EG+ L+L C G V +
Sbjct: 88 -------RGAPVSDPIHLS---VSNDWLILQVPYAPVFEGEPLVLRC--RGWYDKVVYKL 135
Query: 240 YREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYC----RADNGHVPIQSKVVNIPVRI 295
+ G ++ SA + + SD+G+Y C R P+ S V + V+
Sbjct: 136 HYYHDGQAV---RYFHSSANYTVLQARASDSGRYQCSGTMRIPVESAPMFSAKVAVTVQE 192
Query: 296 PVSRPVLTLRSP--GAQAAVGDLLELHCEA----LRGSPPILYQFY 335
PVL + P AA+G ++ L C+ + P+ + FY
Sbjct: 193 LFRAPVLRVMGPREARGAALGGVV-LRCDTRLHPQKRDTPLQFAFY 237
>gi|10835133 Fc fragment of IgG, high affinity Ia, receptor (CD64)
[Homo sapiens]
Length = 374
Score = 96.3 bits (238), Expect = 6e-20
Identities = 63/180 (35%), Positives = 96/180 (53%), Gaps = 6/180 (3%)
Query: 20 LTLVAPSSVF-EGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSDSG 78
L L S VF EG+ + L+C ++ + + Y+++ K F S+ I +S +G
Sbjct: 105 LLLQVSSRVFTEGEPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNG 164
Query: 79 NYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPI-EGGPVSLKCETRLSPQRL 137
Y CS G+ TS + + V+ELF PVL AS P+ EG V+L CET+L QR
Sbjct: 165 TYHCSGMGK---HRYTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRP 221
Query: 138 DVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHV 197
+QL F F+ ++ L G ++S E QI ED+G YWC+A T + K+S + ++ V
Sbjct: 222 GLQLYFSFYMGSKTL-RGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQV 280
Score = 37.7 bits (86), Expect = 0.025
Identities = 78/342 (22%), Positives = 138/342 (40%), Gaps = 60/342 (17%)
Query: 3 LWSL--LVIFDAVTEQADS----LTLVAP-SSVFEGDSIVLKCQ-------GEQNWKIQK 48
+W L L+++ V Q D+ +TL P SVF+ +++ L C+ W +
Sbjct: 1 MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNG 60
Query: 49 MAYHKDNKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQR 108
A + I SA ++DSG Y C S+ +++++ +
Sbjct: 61 TATQTSTPS---------YRITSASVNDSGEYRCQRG-----LSGRSDPIQLEIHRGWL- 105
Query: 109 PVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGS-GWSSSPELQISAV 167
+L SS EG P++L+C +V ++R + W+S+ L I
Sbjct: 106 -LLQVSSRVFTEGEPLALRCHAWKDKLVYNV----LYYRNGKAFKFFHWNSN--LTILKT 158
Query: 168 WSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAP---GGQVTEGQKLIL 224
G+Y C HR + + + P ++ + +P G VT + L
Sbjct: 159 NISHNGTYHCSGMG-KHRYTSAGISVTVK-ELFPAPVLNASVTSPLLEGNLVTLSCETKL 216
Query: 225 LCSVAGGTGNVTFSWYREATGTSMGKKTQR--SLSAELEIPAVKESDAGKYYCRA--DNG 280
L G + FS+Y MG KT R + S+E +I + D+G Y+C A ++G
Sbjct: 217 LLQRPGL--QLYFSFY-------MGSKTLRGRNTSSEYQILTARREDSGLYWCEAATEDG 267
Query: 281 HV-----PIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLL 317
+V ++ +V+ + + PV VL + G V +L
Sbjct: 268 NVLKRSPELELQVLGLQLPTPVWFHVLFYLAVGIMFLVNTVL 309
>gi|110347451 platelet/endothelial cell adhesion molecule [Homo
sapiens]
Length = 738
Score = 77.8 bits (190), Expect = 2e-14
Identities = 118/514 (22%), Positives = 206/514 (40%), Gaps = 73/514 (14%)
Query: 28 VFEGDSIVLKCQGEQNWKIQK---MAYHKDNKELSVFKKFSDFLIQS--AVLSDSGNYFC 82
+ EG + +KC + Q+ + KD K + + + + S A++ SGNY C
Sbjct: 246 IMEGAQLHIKCTIQVTHLAQEFPEIIIQKD-KAIVAHNRHGNKAVYSVMAMVEHSGNYTC 304
Query: 83 STKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQ 142
+ K S+IV + + ELF +P L +S +G ++L C +P
Sbjct: 305 KVESSRI--SKVSSIV-VNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPA-----N 356
Query: 143 FCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPI 202
F +E+ ++ S + D+G+Y C A + ++K + + + +
Sbjct: 357 FTIQKEDTIV-----SQTQDFTKIASKSDSGTYICTAG-IDKVVKKSNTVQIVVCEMLSQ 410
Query: 203 SNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEI 262
+S + + +V +GQ + + C GT +++ + + K + +
Sbjct: 411 PRISYDAQF---EVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDN 467
Query: 263 PAVKESDAGKYYCRADN--GHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELH 320
P ++ +Y C ADN H + S+V+ + V PV +++ S + D++ L
Sbjct: 468 P----TEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIV-LQ 522
Query: 321 CEALRGSPPILYQFYHEDVTLGNSSAPSGGGASF--NLSLTAEHSGNYSCEANNGLGAQC 378
C GS PI Y+FY E S +F + E G Y C A N A
Sbjct: 523 CAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFN--RANH 580
Query: 379 SEAVPVSISGPDGYRRDLMTAGVL---W--GLFGVLGFTGV--ALLLYALFHKISGESSA 431
+ +VP R ++T V+ W GL V+ GV ALL+ A ++ A
Sbjct: 581 ASSVP---------RSKILTVRVILAPWKKGLIAVV-IIGVIIALLIIAAKCYFLRKAKA 630
Query: 432 TNEPRGASRP-----NPQEFTYSSPTPDMEE------------LQPVYVNVGSVDVDVVY 474
P SRP N S P + ++P+ N ++ DV Y
Sbjct: 631 KQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYGHNDDVRNHAMKPINDNKEPLNSDVQY 690
Query: 475 SQVWSMQQPESSANIRTLLENKDSQVIYSSVKKS 508
++V SSA L KD++ +YS V+K+
Sbjct: 691 TEV-----QVSSAESHKDLGKKDTETVYSEVRKA 719
Score = 59.3 bits (142), Expect = 8e-09
Identities = 74/300 (24%), Positives = 124/300 (41%), Gaps = 37/300 (12%)
Query: 100 IKVQELFQRPVLTASSFQPI-EGGPVSLKCE---TRLSPQRLDVQLQFCFFRENQVLGSG 155
+ V E F P S I EG + +KC T L+ + ++ +Q ++ ++
Sbjct: 227 VTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQ----KDKAIVAHN 282
Query: 156 WSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSL----EIRA 211
+ + E +G+Y CK E+ RI K V I ++ L E+ +
Sbjct: 283 RHGNKAVYSVMAMVEHSGNYTCKVES--SRISK--------VSSIVVNITELFSKPELES 332
Query: 212 PGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAG 271
+ +G++L L CS+ G F+ +E T S + + S +SD+G
Sbjct: 333 SFTHLDQGERLNLSCSIPGAPP-ANFTIQKEDTIVSQTQDFTKIAS---------KSDSG 382
Query: 272 KYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPIL 331
Y C A V +S V I V +S+P ++ + + G +E+ CE++ G+ PI
Sbjct: 383 TYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQ-FEVIKGQTIEVRCESISGTLPIS 441
Query: 332 YQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANN--GLGAQCSEAVPVSISGP 389
YQ L NS+ S A F + T + Y C A+N SE + V + P
Sbjct: 442 YQLLKTSKVLENSTKNSNDPAVFKDNPTED--VEYQCVADNCHSHAKMLSEVLRVKVIAP 499
>gi|13489095 sialoadhesin precursor [Homo sapiens]
Length = 1709
Score = 76.6 bits (187), Expect = 5e-14
Identities = 95/346 (27%), Positives = 134/346 (38%), Gaps = 59/346 (17%)
Query: 72 AVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVS-LKCET 130
A +D+G YFC Q + S V + V PVLTA F + G V L C
Sbjct: 380 ATRADTGFYFCEV--QNVHGSERSGPVSVVVNHPPLTPVLTA--FLETQAGLVGILHCSV 435
Query: 131 RLSPQRLDVQLQFCFFREN---------QVLGSGWSSSPELQISAVWSEDTGSYWCKAET 181
P V + + G+ +S L+I + D+G Y C A
Sbjct: 436 VSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGPNSLRLEIRDLEETDSGEYKCSA-- 493
Query: 182 VTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLC-SVAGGTGNVTFSWY 240
T+ + + H +N + + +P +V EGQ + L C S T + FSWY
Sbjct: 494 -TNSLGNATSTLDFH------ANAARLLISPAAEVVEGQAVTLSCRSGLSPTPDARFSWY 546
Query: 241 REATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHV---PIQSKVVNI--PVRI 295
G + L +PA +DAG Y+CRA +GH P V+ + P R
Sbjct: 547 LN------GALLHEGPGSSLLLPAASSTDAGSYHCRARDGHSASGPSSPAVLTVLYPPRQ 600
Query: 296 PVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASF- 354
P L L + GA A LL ++ PP Q H+D + +S PSGGG S
Sbjct: 601 PTFTTRLDLDAAGAGAGRRGLLLCRVDS---DPPARLQLLHKDRVVA-TSLPSGGGCSTC 656
Query: 355 -----NLSLT--------------AEHSGNYSCEANNGLGAQCSEA 381
+ +T E G Y CEA+N LG + A
Sbjct: 657 GGCSPRMKVTKAPNLLRVEIHNPLLEEEGLYLCEASNALGNASTSA 702
Score = 62.4 bits (150), Expect = 9e-10
Identities = 94/399 (23%), Positives = 157/399 (39%), Gaps = 47/399 (11%)
Query: 66 DFLIQSAVLSDSGNY-FCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPV 124
+ L++ DSG+Y F ++ W + +E R AS + +EG V
Sbjct: 99 NLLLKDLQPEDSGSYNFRFEISEVNRWSDVKGTLVTVTEE--PRVPTIASPVELLEGTEV 156
Query: 125 SLKCETRLSPQRLDVQLQF--------CFFRENQVLGSGWSSSPELQISAVWSEDTGSYW 176
C T + V+LQ+ F + +G L ++ W +
Sbjct: 157 DFNCSTPYVCLQEQVRLQWQGQDPARSVTFNSQKFEPTGVGHLETLHMAMSWQDHGRILR 216
Query: 177 CKAETVTHRIRKQSLQSQIHVQ-RIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNV 235
C+ HR QS+IH+Q + V + + G + G+ + L C V V
Sbjct: 217 CQLSVANHRA-----QSEIHLQVKYAPKGVKILLSPSGRNILPGELVTLTCQVNSSYPAV 271
Query: 236 T-FSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVR 294
+ W ++ G + KT L +P SDAG Y C+A+NG +V+ P+
Sbjct: 272 SSIKWLKD--GVRLQTKT-----GVLHLPQAAWSDAGVYTCQAENG----VGSLVSPPIS 320
Query: 295 IPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPIL-YQFYHEDVTLGNSSAPSGGGAS 353
+ + + + SP + L C +P L Y +Y V L ++ + +
Sbjct: 321 LHIFMAEVQV-SPAGPILENQTVTLVCNTPNEAPSDLRYSWYKNHVLLEDAHSHT---LR 376
Query: 354 FNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTA--GVLWGLFGVLGF 411
+L+ A+ +G Y CE N G++ S V V ++ P ++TA GL G+L
Sbjct: 377 LHLATRAD-TGFYFCEVQNVHGSERSGPVSVVVNHPP--LTPVLTAFLETQAGLVGILHC 433
Query: 412 TGVA--LLLYALFH------KISGESSATNEPRGASRPN 442
+ V+ L L H SG+S + G S PN
Sbjct: 434 SVVSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGPN 472
Score = 60.8 bits (146), Expect = 3e-09
Identities = 59/223 (26%), Positives = 85/223 (38%), Gaps = 32/223 (14%)
Query: 166 AVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILL 225
A WS D G Y C+AE + + I + + +S P G + E Q + L+
Sbjct: 295 AAWS-DAGVYTCQAENGVGSLVSPPISLHIFMAEVQVS--------PAGPILENQTVTLV 345
Query: 226 CSVAG-GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPI 284
C+ ++ +SWY+ + + S L + +D G Y+C N H
Sbjct: 346 CNTPNEAPSDLRYSWYKNHV------LLEDAHSHTLRLHLATRADTGFYFCEVQNVHGSE 399
Query: 285 QSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNS 344
+S V++ V P PVLT VG LHC + P H L ++
Sbjct: 400 RSGPVSVVVNHPPLTPVLTAFLETQAGLVG---ILHCSVV-SEPLATLVLSHGGHILAST 455
Query: 345 S-----APSGGGASFNLSLTAE-------HSGNYSCEANNGLG 375
S +P G S SL E SG Y C A N LG
Sbjct: 456 SGDSDHSPRFSGTSGPNSLRLEIRDLEETDSGEYKCSATNSLG 498
Score = 60.8 bits (146), Expect = 3e-09
Identities = 63/242 (26%), Positives = 98/242 (40%), Gaps = 34/242 (14%)
Query: 157 SSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQV 216
++S +L++ + D+GSY C+A V SL Q+ + +S P ++
Sbjct: 856 ANSLKLEVRELGLGDSGSYRCEATNVLGS-SNTSLFFQVRGAWVQVS--------PSPEL 906
Query: 217 TEGQKLILLCSVAGGTGNVT-FSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYC 275
EGQ ++L C V G T + WYR+ G+ Q S SA L A+ + AG Y+C
Sbjct: 907 QEGQAVVLSCQVHTGVPEGTSYRWYRD------GQPLQESTSATLRFAAITLTQAGAYHC 960
Query: 276 RADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFY 335
+A S I + + + +TL + G L L C + PP +
Sbjct: 961 QAQAPGSATTSLAAPISLHVSYAPRHVTLTTL-MDTGPGRLGLLLCR-VDSDPPAQLRLL 1018
Query: 336 HED----VTLGNSSAPSGGGASFNLSLT------------AEHSGNYSCEANNGLGAQCS 379
H D TL P G ++++ E G Y CEA+N LG +
Sbjct: 1019 HGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRLEIHGAMLEDEGVYICEASNTLGQASA 1078
Query: 380 EA 381
A
Sbjct: 1079 SA 1080
Score = 45.8 bits (107), Expect = 9e-05
Identities = 60/232 (25%), Positives = 92/232 (39%), Gaps = 28/232 (12%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQK 221
L+I ED G Y C+A ++ + + S + Q + NV + PG V EGQ
Sbjct: 1052 LEIHGAMLEDEGVYICEA---SNTLGQASASADFDAQAV---NVQVW---PGATVREGQL 1102
Query: 222 LILLCSV-AGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCR-ADN 279
+ L C V +T++WY++ QR + + +P V DA Y C
Sbjct: 1103 VNLTCLVWTTHPAQLTYTWYQDG--------QQRLDAHSIPLPNVTVRDATSYRCGVGPP 1154
Query: 280 GHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDV 339
G P S+ P+ + V LR + G L L + PP H
Sbjct: 1155 GRAPRLSR----PITLDVLYAPRNLRLTYLLESHGGQLALVLCTVDSRPPAQLALSHAGR 1210
Query: 340 TLGNSSAPSGGGASFNLSLTA---EHSGNYSCEANNGLGAQCSEAVPVSISG 388
L +S+A S + L L G YSC A + LG Q + ++ + + G
Sbjct: 1211 LLASSTAASVPN-TLRLELRGPQPRDEGFYSCSARSPLG-QANTSLELRLEG 1260
Score = 44.7 bits (104), Expect = 2e-04
Identities = 44/169 (26%), Positives = 69/169 (40%), Gaps = 13/169 (7%)
Query: 219 GQKLILLCSV-AGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRA 277
GQ ++LC+V + + S +S +L EL P + D G Y C A
Sbjct: 1186 GQLALVLCTVDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPR--DEGFYSCSA 1243
Query: 278 DNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHE 337
+ P+ ++ +R+ R +L +P A G + + C P LY +YH
Sbjct: 1244 RS---PLGQANTSLELRLEGVRVIL---APEAAVPEGAPITVTCADPAAHAPTLYTWYHN 1297
Query: 338 DVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSI 386
L A S SF L T H+G YSC+A + G + S + +
Sbjct: 1298 GRWLQEGPAAS---LSF-LVATRAHAGAYSCQAQDAQGTRSSRPAALQV 1342
Score = 42.4 bits (98), Expect = 0.001
Identities = 49/189 (25%), Positives = 70/189 (37%), Gaps = 36/189 (19%)
Query: 209 IRAPGGQVTEGQKLILLCSVAGG---TGNVTFSWYREATGTSMGKKTQRSLSAE----LE 261
+ PG V EG L L C + GG GN TF+W+ R L AE L
Sbjct: 1448 VAEPGLDVPEGAALNLSCRLLGGPGPVGNSTFAWF----------WNDRRLHAEPVPTLA 1497
Query: 262 IPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHC 321
V + AG Y+C A+ S V + V P P + + + + +L+
Sbjct: 1498 FTHVARAQAGMYHCLAELPTGAAASAPVMLRVLYPPKTPTMMV-FVEPEGGLRGILDCRV 1556
Query: 322 EALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNL--------------SLTAEHSGNYS 367
+ S P+ H L SS P G A ++ +L G Y
Sbjct: 1557 D----SEPLASLTLHLGSRLVASSQPQGAPAEPHIHVLASPNALRVDIEALRPSDQGEYI 1612
Query: 368 CEANNGLGA 376
C A+N LG+
Sbjct: 1613 CSASNVLGS 1621
Score = 35.4 bits (80), Expect = 0.12
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 11/131 (8%)
Query: 257 SAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDL 316
S +LE+ + D+G Y C A N + S ++ ++ R SP + G
Sbjct: 858 SLKLEVRELGLGDSGSYRCEATN---VLGSSNTSLFFQV---RGAWVQVSPSPELQEGQA 911
Query: 317 LELHCEALRGSPP-ILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLG 375
+ L C+ G P Y++Y + L S++ + A+ L+ +G Y C+A
Sbjct: 912 VVLSCQVHTGVPEGTSYRWYRDGQPLQESTSATLRFAAITLT----QAGAYHCQAQAPGS 967
Query: 376 AQCSEAVPVSI 386
A S A P+S+
Sbjct: 968 ATTSLAAPISL 978
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 74.7 bits (182), Expect = 2e-13
Identities = 103/420 (24%), Positives = 172/420 (40%), Gaps = 63/420 (15%)
Query: 13 VTEQADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKF-------- 64
+TE+A S+ V +GD L+ + +I + KD +EL++ K+
Sbjct: 4581 ITEEAVSI------DVTQGDPATLQVKFSGTKEITAK-WFKDGQELTLGSKYKISVTDTV 4633
Query: 65 SDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTAS--SFQPIEGG 122
S I S DSG Y + + ++S +I V +L P T I+G
Sbjct: 4634 SILKIISTEKKDSGEYTFEVQNDV---GRSSCKARINVLDLIIPPSFTKKLKKMDSIKGS 4690
Query: 123 PVSLKCETRLSPQRLDVQLQFCFFRENQVLGSG-------WSSSPELQISAVWSEDTGSY 175
+ L+C S + +Q +F+++Q + + ++ L+IS + D+G+Y
Sbjct: 4691 FIDLECIVAGS-HPISIQ----WFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTY 4745
Query: 176 WCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNV 235
C A T++ + V+ P + P Q + L ++ GGT +
Sbjct: 4746 TCSA---TNKAGHNQCSGHLTVKEPPYF-----VEKPQSQDVNPNTRVQLKALVGGTAPM 4797
Query: 236 TFSWYREATGTSMGKKT---QRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSK----V 288
T W+++ G + S LE+ A K +D+G Y C+ N SK V
Sbjct: 4798 TIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFV 4857
Query: 289 VNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHE--DVTLGNSSA 346
P I PVL LR+ G C+ + G+P I +Y + ++T
Sbjct: 4858 KEPPQFIKKPSPVLVLRN-------GQSTTFECQ-ITGTPKIRVSWYLDGNEITAIQKHG 4909
Query: 347 PS--GGGASFNLS-LTAEHSGNYSCEANNGLG-AQCSEAVPVSISGPDGYRRDLMTAGVL 402
S G A+F +S E+SG Y CEA N G A CS + + + P + R+L V+
Sbjct: 4910 ISFIDGLATFQISGARVENSGTYVCEARNDAGTASCS--IELKVKEPPTFIRELKPVEVV 4967
Score = 67.8 bits (164), Expect = 2e-11
Identities = 86/366 (23%), Positives = 148/366 (40%), Gaps = 46/366 (12%)
Query: 48 KMAYHKDNKELSVFKKF--------SDFLIQSAVLSDSGNYFCSTKGQL--FLWDKTSNI 97
K ++KD + L KK+ + SA L DSG Y ++ + T +
Sbjct: 4047 KPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTV 4106
Query: 98 VKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSG-- 155
+ + F +P+ S + G L C+ S + ++ +F++ + + +
Sbjct: 4107 LDRDIAPFFTKPLRNVDS---VVNGTCRLDCKIAGS-----LPMRVSWFKDGKEIAASDR 4158
Query: 156 -----WSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIR 210
+ L+I V D G++ C+A T+ + + + VQ P +
Sbjct: 4159 YRIAFVEGTASLEIIRVDMNDAGNFTCRA---TNSVGSKDSSGALIVQEPPSF-----VT 4210
Query: 211 APGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKK---TQRSLSAELEIPAVKE 267
PG + + L S G+ +T W++ G T+ +L + LE+ VK
Sbjct: 4211 KPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKT 4270
Query: 268 SDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGS 327
SD+G Y C+ N ++ N+ V+ P + + P GD +L C+ + G+
Sbjct: 4271 SDSGTYTCKVSNVAGGVECSA-NLFVKEPAT--FVEKLEPSQLLKKGDATQLACK-VTGT 4326
Query: 328 PPILYQFYHEDVTLGNSSAP--SGGGASFNLSLT---AEHSGNYSCEANNGLGA-QCSEA 381
PPI ++ D + SS S ++ L LT E SG Y CEA N G+ CS
Sbjct: 4327 PPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSI 4386
Query: 382 VPVSIS 387
V V S
Sbjct: 4387 VIVKES 4392
Score = 66.6 bits (161), Expect = 5e-11
Identities = 96/411 (23%), Positives = 163/411 (39%), Gaps = 46/411 (11%)
Query: 20 LTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNK-----ELSVF--KKFSDFLIQSA 72
+T + P GDS+ L+CQ +I Y D K E + + +
Sbjct: 6082 VTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKV 6141
Query: 73 VLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIE---GGPVSLKCE 129
++DSG Y C + + S+ ++QE Q P A + IE G PV+L C
Sbjct: 6142 NINDSGEYTCKAENSI---GTASSKTVFRIQER-QLPPSFARQLKDIEQTVGLPVTLTCR 6197
Query: 130 TRLSPQRLDVQLQFCFFRENQVLG-------SGWSSSPELQISAVWSEDTGSYWCKAETV 182
S +Q C++R+ +L S + L+I +G Y C A
Sbjct: 6198 LNGS-----APIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSA--- 6249
Query: 183 THRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYRE 242
++ + S +++ R P + +I+ V G+ C V G + +W ++
Sbjct: 6250 SNPLGTASSSARL-TAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQP-MRITWSKD 6307
Query: 243 ATGTSMGKK---TQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSR 299
G T + L I V + D+G+Y C+A N + + + + +
Sbjct: 6308 NKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATND---VGKDMCSAQLSVKEPP 6364
Query: 300 PVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLT 359
+ A G+ ++L C+ + GSP I ++ D L S + + LT
Sbjct: 6365 KFVKKLEASKVAKQGESIQLECK-ISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLT 6423
Query: 360 -----AEHSGNYSCEANNGLG-AQCSEAVPVSISGPDGYRRDLMTAGVLWG 404
AE SG+Y CEA+NG+G A CS A +++ P + + G L G
Sbjct: 6424 INEASAEDSGDYICEAHNGVGDASCSTA--LTVKAPPVFTQKPSPVGALKG 6472
Score = 60.5 bits (145), Expect = 4e-09
Identities = 80/343 (23%), Positives = 134/343 (39%), Gaps = 44/343 (12%)
Query: 54 DNKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRP---V 110
DN +S + I+S SG Y C K + S + + L Q P V
Sbjct: 5092 DNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNE-------SGVERCYAFLLVQEPAQIV 5144
Query: 111 LTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFREN-QVLGSGWSSSP------ELQ 163
A S E P++L+C +P+ L+ + ++ Q++ S + S +
Sbjct: 5145 EKAKSVDVTEKDPMTLECVVAGTPE-----LKVKWLKDGKQIVPSRYFSMSFENNVASFR 5199
Query: 164 ISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHV--QRIPISNVSLEIRAPGGQVTEGQK 221
I +V +D+G Y K E + S + + V Q IP S + G
Sbjct: 5200 IQSVMKQDSGQYTFKVE---NDFGSSSCDAYLRVLDQNIPPSFTKKLTKM---DKVLGSS 5253
Query: 222 LILLCSVAGGTGNVTFSWYREATGTSMGKKTQ---RSLSAELEIPAVKESDAGKYYCRAD 278
+ + C V+G ++ W+++ S K + S LE+ ++ D Y C+
Sbjct: 5254 IHMECKVSGSLP-ISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVS 5312
Query: 279 NGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHED 338
N V I + V P L PG Q A+ D L+G+PP +++ +D
Sbjct: 5313 N--VAGDDACSGI---LTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDD 5367
Query: 339 VTLGNSS----APSGGGASFNL-SLTAEHSGNYSCEANNGLGA 376
V L + G + NL S+ A +G Y+C N +G+
Sbjct: 5368 VELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGS 5410
Score = 60.5 bits (145), Expect = 4e-09
Identities = 90/384 (23%), Positives = 152/384 (39%), Gaps = 51/384 (13%)
Query: 28 VFEGDSIVLKCQ--GEQNWKIQKMAYHKDNKELSVFKKFS--------DFLIQSAVLSDS 77
V G+S +C G Q +I + KDNKE+ ++ I DS
Sbjct: 6282 VIAGESADFECHVTGAQPMRI---TWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDS 6338
Query: 78 GNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRL 137
G Y C + D S + +K F + L AS +G + L+C+ SP+
Sbjct: 6339 GQYTCQATNDVGK-DMCSAQLSVKEPPKFVKK-LEASKVAK-QGESIQLECKISGSPE-- 6393
Query: 138 DVQLQFCFFRENQVLGSGW-------SSSPELQISAVWSEDTGSYWCKAETVTHRIRKQS 190
++ +FR + L W +S L I+ +ED+G Y C+A + + S
Sbjct: 6394 ---IKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAH---NGVGDAS 6447
Query: 191 LQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGK 250
+ + V+ P+ + +P G + +G +IL C ++G T W ++ K
Sbjct: 6448 CSTALTVKAPPVFT---QKPSPVGAL-KGSDVILQCEISG-TPPFEVVWVKDRKQVRNSK 6502
Query: 251 K---TQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSP 307
K T + L I ++ SD G+Y+C+A N + S + V+ P +
Sbjct: 6503 KFKITSKHFDTSLHILNLEASDVGEYHCKATN---EVGSDTCSCSVKFK-EPPRFVKKLS 6558
Query: 308 GAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNL------SLTAE 361
+GD +EL + G PI + + + S + N+ S A
Sbjct: 6559 DTSTLIGDAVELRA-IVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEAS 6617
Query: 362 HSGNYSCEANNGLG-AQCSEAVPV 384
+SG Y C+ N G +CS + V
Sbjct: 6618 NSGKYICQIKNDAGMRECSAVLTV 6641
Score = 60.1 bits (144), Expect = 5e-09
Identities = 93/388 (23%), Positives = 146/388 (37%), Gaps = 45/388 (11%)
Query: 42 QNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIK 101
Q +K + Y D + K S I + D G Y C + + S +
Sbjct: 3488 QWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE---YGSVSCTATLT 3544
Query: 102 VQELFQRPVLTA-SSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSP 160
V E + L+ S G C +P + Q G+ S SP
Sbjct: 3545 VTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIW---------QKDGAALSPSP 3595
Query: 161 E-----------LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEI 209
L++S + +D G Y CKA +++ Q+++ + P LE
Sbjct: 3596 NWRISDAENKHILELSNLTIQDRGVYSCKA---SNKFGADICQAELIIIDKPHFIKELE- 3651
Query: 210 RAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLS---AELEIPAVK 266
Q +K+ L C V VT +W ++ GK + A LEIP K
Sbjct: 3652 ---PVQSAINKKVHLECQVDEDR-KVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAK 3707
Query: 267 ESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRG 326
D+G Y C A N S + VR P S + P G+ LHC+ L+G
Sbjct: 3708 LKDSGTYVCTASN-EAGSSSCSATVTVREPPS--FVKKVDPSYLMLPGESARLHCK-LKG 3763
Query: 327 SPPILYQFYHEDVTLGNSSAPS----GGGASFNLS-LTAEHSGNYSCEANNGLGAQCSEA 381
SP I ++ + L S+ A +++ + E SG+YSCEA N +G+ S +
Sbjct: 3764 SPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSD-SCS 3822
Query: 382 VPVSISGPDGYRRDLMTAGVLWGLFGVL 409
+ I P + + L A ++ G +L
Sbjct: 3823 TEIVIKEPPSFIKTLEPADIVRGTNALL 3850
Score = 59.7 bits (143), Expect = 6e-09
Identities = 70/250 (28%), Positives = 108/250 (43%), Gaps = 22/250 (8%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQK 221
L+I + ED G Y C E + K S +QI + P LE +V+ G
Sbjct: 7925 LEIPSSTVEDAGQYNCYIENASG---KDSCSAQILILEPPYFVKQLE----PVKVSVGDS 7977
Query: 222 LILLCSVAGGTGNVTFSWYREATG---TSMGKKTQRSLSAELEIPAVKESDAGKYYCRAD 278
L C +AG T + SWY+ T T+ K R+ A L V +D+G+Y C+A+
Sbjct: 7978 ASLQCQLAG-TPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAE 8036
Query: 279 N--GHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYH 336
N G V + + ++P P + + Q VG + C A+ GS PI +Y
Sbjct: 8037 NSVGEVSASTFLTVQEQKLP---PSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYK 8092
Query: 337 EDVTLGNS----SAPSGGGASFNLSLTAEH-SGNYSCEANNGLGAQCSEAVPVSISGPDG 391
+ L +S ++ A+ N+ T +G YSC A N +G+ S A + G +
Sbjct: 8093 DGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNP 8152
Query: 392 YRRDLMTAGV 401
D+ A V
Sbjct: 8153 PFFDIRLAPV 8162
Score = 57.4 bits (137), Expect = 3e-08
Identities = 91/378 (24%), Positives = 154/378 (40%), Gaps = 66/378 (17%)
Query: 31 GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVL--------SDSGNYFC 82
G S+V++C+ + I +H+ N E+S +K+ L + SDSG+Y C
Sbjct: 7696 GSSVVMECKVYGSPPISVSWFHEGN-EISSGRKYQTTLTDNTCALTVNMLEESDSGDYTC 7754
Query: 83 STKGQLFLWDKTSNIVKIKVQELFQRP----VLTASS--FQPIEGG--PVSL---KCETR 131
+ ++ + + Q+P VLT ++ F I G P S+ K +
Sbjct: 7755 IATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSE 7814
Query: 132 LSP-QRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQS 190
L P R +V L+ S EL++ V + +G Y C V++ K S
Sbjct: 7815 LVPGDRCNVSLE--------------DSVAELELFDVDTSQSGEYTC---IVSNEAGKAS 7857
Query: 191 LQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGK 250
+ +++ + P V R + +G+ LIL + G T ++ +W + + +
Sbjct: 7858 CTTHLYI-KAPAKFVK---RLNDYSIEKGKPLILEGTFTG-TPPISVTWKKNGINVTPSQ 7912
Query: 251 K---TQRSLSAELEIPAVKESDAGKYYCRADNG----HVPIQSKVVNIPVRIPVSRPVLT 303
+ T SA LEIP+ DAG+Y C +N Q ++ P + PV
Sbjct: 7913 RCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPV-- 7970
Query: 304 LRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSA------PSGGGASFNLS 357
+ +VGD L C+ L G+P I +Y D L ++ + FN
Sbjct: 7971 ------KVSVGDSASLQCQ-LAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFN-Q 8022
Query: 358 LTAEHSGNYSCEANNGLG 375
+ SG Y C+A N +G
Sbjct: 8023 VDINDSGEYICKAENSVG 8040
Score = 57.0 bits (136), Expect = 4e-08
Identities = 63/228 (27%), Positives = 88/228 (38%), Gaps = 18/228 (7%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQK 221
L+I D G Y C+ E R +L S + LE G
Sbjct: 6043 LEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAV-------GDS 6095
Query: 222 LILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLS---AELEIPAVKESDAGKYYCRAD 278
+ L C VAG T +T SWY+ T + + + A L V +D+G+Y C+A+
Sbjct: 6096 VSLQCQVAG-TPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAE 6154
Query: 279 NGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHED 338
N SK V ++ P + + VG + L C L GS PI +Y +
Sbjct: 6155 NSIGTASSKTV-FRIQERQLPPSFARQLKDIEQTVGLPVTLTCR-LNGSAPIQVCWYRDG 6212
Query: 339 VTLGN-----SSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEA 381
V L + +S L HSG YSC A+N LG S A
Sbjct: 6213 VLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSA 6260
Score = 55.8 bits (133), Expect = 9e-08
Identities = 47/171 (27%), Positives = 69/171 (40%), Gaps = 11/171 (6%)
Query: 219 GQKLILLCSVAGGTGNVTFSWYREATGTSMG---KKTQRSLSAELEIPAVKESDAGKYYC 275
G+ L C V GT + SWY+E T K ++ A L I V SD G+Y C
Sbjct: 7034 GEPATLQCKV-DGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSC 7092
Query: 276 RADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFY 335
+ADN + S V + ++ P + +G + C + GS P+ +Y
Sbjct: 7093 KADNSVGAVASSAV-LVIKARKLPPFFARKLKDVHETLGFPVAFECR-INGSEPLQVSWY 7150
Query: 336 HEDVTLGN-----SSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEA 381
+ V L + +S L H G Y+C A+N LG S A
Sbjct: 7151 KDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSA 7201
Score = 55.1 bits (131), Expect = 2e-07
Identities = 60/234 (25%), Positives = 103/234 (44%), Gaps = 18/234 (7%)
Query: 158 SSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVT 217
+S L + V D+G Y C A + + K S +Q++++ I + + + T
Sbjct: 8206 NSAHLTVLKVDKGDSGQYTCYA---VNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEET 8262
Query: 218 EGQKLILLCSVAGGTGNVTFSWYR---EATGTSMGKKTQRSLSAELEIPAVKESDAGKYY 274
EG L VAG +T +WY+ E TS + T ++ + L++ +DAG Y
Sbjct: 8263 EGNSFKLEGRVAGSQP-ITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYT 8321
Query: 275 CRADN--GHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILY 332
C+ N G S +V ++ P PV + G+ ++L C ++GS PI
Sbjct: 8322 CKVSNDAGSALCTSSIV---IKEPKKPPVFDQHLTPVTVSEGEYVQLSCH-VQGSEPIRI 8377
Query: 333 QFYHEDVTLGNSSAPS----GGGASFNLSLTAE-HSGNYSCEANNGLGAQCSEA 381
Q+ + S S G A L A+ SG+Y C+A+N G+ +++
Sbjct: 8378 QWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKS 8431
Score = 54.7 bits (130), Expect = 2e-07
Identities = 83/395 (21%), Positives = 151/395 (38%), Gaps = 61/395 (15%)
Query: 11 DAVTEQADSLTLVAPSSVFEGDSIV-LKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLI 69
D T D++ L A F+ S+V LK +GE + +N +S + +
Sbjct: 6559 DTSTLIGDAVELRAIVEGFQPISVVWLKDRGE-------VIRESENTRISFIDNIATLQL 6611
Query: 70 QSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCE 129
S S+SG Y C K + + ++ + ++ + ++P G P +L+C
Sbjct: 6612 GSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKP----EPMTVTTGNPFALECV 6667
Query: 130 TRLSPQRLDVQLQFCFFRENQVLGSG-------WSSSPELQISAVWSEDTGSYWCKAETV 182
+P +L +F++ + L + + L+I D G Y + V
Sbjct: 6668 VTGTP-----ELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLY---SFEV 6719
Query: 183 THRIRKQSLQSQIHV--QRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWY 240
+ + K + +HV + +P S + + G ++L C V+ G+ ++ W+
Sbjct: 6720 KNSVGKSNCTVSVHVSDRIVPPSFIR---KLKDVNAILGASVVLECRVS-GSAPISVGWF 6775
Query: 241 REATGTSMGKKTQRSLS---AELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPV 297
++ G K Q S S L + ++ SD G Y C A N + V + V
Sbjct: 6776 QDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAV-----LTV 6830
Query: 298 SRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLS 357
P ++P + + + +RG+PP +++ S G S N+S
Sbjct: 6831 QEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWF-------KGSRELVPGESCNIS 6883
Query: 358 L------------TAEHSGNYSCEANNGLG-AQCS 379
L SG+YSC N G A C+
Sbjct: 6884 LEDFVTELELFEVQPLESGDYSCLVTNDAGSASCT 6918
Score = 53.9 bits (128), Expect = 3e-07
Identities = 98/434 (22%), Positives = 176/434 (40%), Gaps = 57/434 (13%)
Query: 22 LVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVL------- 74
L A V GDS L+C+ + +I ++ + ++ EL K+ I S +
Sbjct: 5429 LEASKIVKAGDSSRLECKIAGSPEI-RVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLS 5487
Query: 75 -SDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPI----EGGPVSLKCE 129
DSG++ C + TS K+ V+E PV SSF PI + VSL+CE
Sbjct: 5488 TEDSGDFICEAQNPA---GSTSCSTKVIVKE---PPVF--SSFPPIVETLKNAEVSLECE 5539
Query: 130 TRLSPQRLDV----QLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHR 185
+P V + Q ++ ++ + +S + I V + D G Y CKA+ +
Sbjct: 5540 LSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTS--IHILNVDTSDIGEYHCKAQ---NE 5594
Query: 186 IRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATG 245
+ + + ++ P L V G+ L S+ G + W +E
Sbjct: 5595 VGSDTCVCTVKLKEPPRFVSKLNSLT----VVAGEPAELQASIEGAQP-IFVQWLKEKEE 5649
Query: 246 TSMGKKTQRSLSAE----LEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPV 301
+ R E L+ + ++AGKY C+ N ++ + + V P V
Sbjct: 5650 VIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDG-GMRENMATLMVLEPA---V 5705
Query: 302 LTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFN------ 355
+ ++ VG+ L C+ + G+P + ++Y + L +S+ + +N
Sbjct: 5706 IVEKAGPMTVTVGETCTLECK-VAGTPELSVEWYKDGKLL--TSSQKHKFSFYNKISSLR 5762
Query: 356 -LSLTAEHSGNYSCEANNGLG-AQCSEAVPVSISG-PDGYRRDLMTAGVLWGLFGVL--G 410
LS+ + +G Y+ + N +G + C+ V VS P + R L G + G +L
Sbjct: 5763 ILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECK 5822
Query: 411 FTGVALLLYALFHK 424
G + + A FH+
Sbjct: 5823 VAGSSPISVAWFHE 5836
Score = 52.8 bits (125), Expect = 7e-07
Identities = 89/422 (21%), Positives = 170/422 (40%), Gaps = 60/422 (14%)
Query: 13 VTEQADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELS------VFKKFSD 66
V E +T V G ++ LK + + + + + K NKEL + K+ +
Sbjct: 4202 VQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLT-IRWFKGNKELVSGGSCYITKEALE 4260
Query: 67 FLIQSAVL--SDSGNYFCSTKGQLFLWDKTSNI---VKIKVQELFQRPVLTASSFQPIE- 120
++ ++ SDSG Y C K SN+ V+ + P +P +
Sbjct: 4261 SSLELYLVKTSDSGTYTC----------KVSNVAGGVECSANLFVKEPATFVEKLEPSQL 4310
Query: 121 ---GGPVSLKCETRLSPQRLDVQLQFCFFRENQVLG-------SGWSSSPELQISAVWSE 170
G L C+ +P ++ +F ++ + S S+ L+++ V E
Sbjct: 4311 LKKGDATQLACKVTGTPP-----IKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIE 4365
Query: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230
D+G Y C+A+ + S + V+ P + +V + ++LL VAG
Sbjct: 4366 DSGEYMCEAQ---NEAGSDHCSSIVIVKESPYFTKEFKPI----EVLKEYDVMLLAEVAG 4418
Query: 231 GTGNVTFSWYREATGTSMGKKTQRSLS---AELEIPAVKESDAGKYYCRADNGHVPIQSK 287
T +W+++ T G+K + + L+I +DAG+Y CR N + S
Sbjct: 4419 -TPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTN---EVGSS 4474
Query: 288 VVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHE--DVTLGNSS 345
+ + R+ + P ++ + +++ L+GS PI + + ++T ++
Sbjct: 4475 ICS--ARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNI 4532
Query: 346 APS--GGGASFNLS-LTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVL 402
+ AS LS + +H G Y C+A N G Q A+ +S+ P + ++ V
Sbjct: 4533 RMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSAL-LSVKEPATITEEAVSIDVT 4591
Query: 403 WG 404
G
Sbjct: 4592 QG 4593
Score = 52.4 bits (124), Expect = 1e-06
Identities = 86/377 (22%), Positives = 150/377 (39%), Gaps = 36/377 (9%)
Query: 48 KMAYHKDNKELSVFKKF--------SDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVK 99
++ ++KD ++L KK+ + I + SD G Y C + ++ D VK
Sbjct: 5547 EVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGS-DTCVCTVK 5605
Query: 100 IKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQL---QFCFFRENQVLGSGW 156
+K F V +S + G P L+ Q + VQ + RE++ + +
Sbjct: 5606 LKEPPRF---VSKLNSLTVVAGEPAELQASIE-GAQPIFVQWLKEKEEVIRESENIRITF 5661
Query: 157 SSS-PELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQ 215
+ LQ + + G Y C+ I+ + + + + +A
Sbjct: 5662 VENVATLQFAKAEPANAGKYICQ-------IKNDGGMRENMATLMVLEPAVIVEKAGPMT 5714
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLS---AELEIPAVKESDAGK 272
VT G+ L C VAG T ++ WY++ + +K + S + L I +V+ DAG
Sbjct: 5715 VTVGETCTLECKVAG-TPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGT 5773
Query: 273 YYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILY 332
Y + N +V S + V P T R +G L C+ + GS PI
Sbjct: 5774 YTFQVQN-NVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECK-VAGSSPISV 5831
Query: 333 QFYHEDVTLGNSSAP----SGGGASFNL-SLTAEHSGNYSCEANNGLGAQCSEAVPVSIS 387
++HE + + + S + L SL + GNY+C A N G+ AV +++
Sbjct: 5832 AWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAV-LTVQ 5890
Query: 388 GPDGYRRDLMTAGVLWG 404
P + ++ VL G
Sbjct: 5891 EPPSFVKEPEPLEVLPG 5907
Score = 50.4 bits (119), Expect = 4e-06
Identities = 91/404 (22%), Positives = 153/404 (37%), Gaps = 53/404 (13%)
Query: 10 FDAVTEQADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS---- 65
F V E A + V E D + L+C ++ K+ + KD K++ + FS
Sbjct: 5134 FLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPEL-KVKWLKDGKQIVPSRYFSMSFE 5192
Query: 66 ----DFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTA--SSFQPI 119
F IQS + DSG Y + + +S ++V + P T + +
Sbjct: 5193 NNVASFRIQSVMKQDSGQYTFKVEND---FGSSSCDAYLRVLDQNIPPSFTKKLTKMDKV 5249
Query: 120 EGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSG-------WSSSPELQISAVWSEDT 172
G + ++C+ S L + Q+ F++ + + + S L+++ + EDT
Sbjct: 5250 LGSSIHMECKVSGS---LPISAQW--FKDGKEISTSAKYRLVCHERSVSLEVNNLELEDT 5304
Query: 173 GSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGT 232
+Y CK V + + V+ P V PG Q + ++ GT
Sbjct: 5305 ANYTCKVSNVAG---DDACSGILTVKEPPSFLVK-----PGRQQAIPDSTVEFKAILKGT 5356
Query: 233 GNVTFSWYREATGTSMGKKTQRSLSAE---LEIPAVKESDAGKYYCRADNGHVPIQSKVV 289
W+++ G K L L + +V S G+Y C HV
Sbjct: 5357 PPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTC-----HVTNDVGSD 5411
Query: 290 NIPVRIPVSRPVLTLRSPGAQAAV--GDLLELHCEALRGSPPILYQFYHEDVTLGNSSA- 346
+ + V+ P ++ A V GD L C+ + GSP I ++ + L S
Sbjct: 5412 SCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECK-IAGSPEIRVVWFRNEHELPASDKY 5470
Query: 347 -----PSGGGASFNLSLTAEHSGNYSCEANNGLGA-QCSEAVPV 384
S N +L+ E SG++ CEA N G+ CS V V
Sbjct: 5471 RMTFIDSVAVIQMN-NLSTEDSGDFICEAQNPAGSTSCSTKVIV 5513
Score = 48.1 bits (113), Expect = 2e-05
Identities = 86/396 (21%), Positives = 155/396 (39%), Gaps = 74/396 (18%)
Query: 48 KMAYHKDNKELSVFKKFSDFLIQSAVL--------SDSGNYFCSTKGQLFLWDKTSNIVK 99
K+ ++KD E+ KF + S + DSG+Y C S+
Sbjct: 7336 KVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAA---GSASSSTS 7392
Query: 100 IKVQELFQRPVLTASSFQPIE---GGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGW 156
+KV+E P + PIE G V L+CE + +P ++++ + L SG
Sbjct: 7393 LKVKE----PPIFRKKPHPIETLKGADVHLECELQGTPP-----FHVSWYKDKRELRSGK 7443
Query: 157 SSS-------PELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIP-----ISN 204
+ I V + D G Y CKA T+ + + I ++ P +S+
Sbjct: 7444 KYKIMSENFLTSIHILNVDAADIGEYQCKA---TNDVGSDTCVGSIALKAPPRFVKKLSD 7500
Query: 205 VSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLS-----AE 259
+S + K + L + G ++ W+++ G + + +S A
Sbjct: 7501 ISTVVG----------KEVQLQTTIEGAEPISVVWFKDK-GEIVRESDNIWISYSENIAT 7549
Query: 260 LEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLEL 319
L+ V+ ++AGKY C+ N +Q + V P + + + + GD L
Sbjct: 7550 LQFSRVEPANAGKYTCQIKN-DAGMQECFATLSVLEPAT---IVEKPESIKVTTGDTCTL 7605
Query: 320 HCEALRGSPPILYQFYHE--DVTLGNSSAPSGGGASFN-------LSLTAEHSGNYSCEA 370
C + G+P + +++ + ++T N S FN +++ SG YS E
Sbjct: 7606 EC-TVAGTPELSTKWFKDGKELTSDNKYKIS----FFNKVSGLKIINVAPSDSGVYSFEV 7660
Query: 371 NNGLGA-QCSEAVPVS-ISGPDGYRRDLMTAGVLWG 404
N +G C+ ++ VS + P + R L L G
Sbjct: 7661 QNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSG 7696
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/393 (22%), Positives = 154/393 (39%), Gaps = 68/393 (17%)
Query: 48 KMAYHKDNKELSV-FK-KFSD------FLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVK 99
K++++K+ + LS FK KF L+ A D+ Y C K + TS +
Sbjct: 3269 KISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGV-ATTSASLS 3327
Query: 100 IKVQELF----QRPVLTASSFQPI------EGGPVSLKC-----ETRLSPQRLDVQLQFC 144
++V E+ + PV + P+ EG P +C + ++S D +++
Sbjct: 3328 VEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPS 3387
Query: 145 -FFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETV------THRIRKQSLQSQIHV 197
FFR Q + + +L+I+ + ED G+Y A T + ++ +S +H
Sbjct: 3388 RFFRMTQ-----FEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILH- 3441
Query: 198 QRIPISNVSLEIRAPGG--------QVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMG 249
+RI + +E++A +V G C + NV F W++
Sbjct: 3442 ERIE-QEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAP-NVRFQWFKAGREIYES 3499
Query: 250 KKTQRSLS---AELEIPAVKESDAGKYYCRADNGHVPIQ-SKVVNIPVRIPVSRPVLTLR 305
K S + LEI + D G+Y C+A N + + + + + P P R
Sbjct: 3500 DKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYP---PTFLSR 3556
Query: 306 SPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNL--------- 356
VG + C P++ + +D G + +PS +
Sbjct: 3557 PKSLTTFVGKAAKFICTVT--GTPVIETIWQKD---GAALSPSPNWRISDAENKHILELS 3611
Query: 357 SLTAEHSGNYSCEANNGLGAQCSEAVPVSISGP 389
+LT + G YSC+A+N GA +A + I P
Sbjct: 3612 NLTIQDRGVYSCKASNKFGADICQAELIIIDKP 3644
Score = 46.6 bits (109), Expect = 5e-05
Identities = 90/393 (22%), Positives = 151/393 (38%), Gaps = 55/393 (13%)
Query: 25 PSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNK-------ELSVFKKFSDFLIQSAVLSDS 77
P V GDS L+CQ +I Y D K ++ + + ++DS
Sbjct: 7969 PVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDS 8028
Query: 78 GNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTAS--SFQPIEGGPVSLKCETRLSPQ 135
G Y C + + + S + VQE P + Q G PV C S
Sbjct: 8029 GEYICKAENSV---GEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEP 8085
Query: 136 RLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDT-----------GSYWCKAETVTH 184
+ ++++ + L SP +Q S + + T G Y C T T+
Sbjct: 8086 -----ISVSWYKDGKPL----KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSC---TATN 8133
Query: 185 RIRKQSLQSQIHV---QRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYR 241
I S +++ + + P ++ L AP V G+ C V G T + SW +
Sbjct: 8134 PIGSASSSARLILTEGKNPPFFDIRL---APVDAVV-GESADFECHVTG-TQPIKVSWAK 8188
Query: 242 EATGTSMGKKTQRSL---SAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVS 298
++ G K Q S SA L + V + D+G+Y C A N V S + ++ +
Sbjct: 8189 DSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVN-EVGKDSCTAQLNIKERLI 8247
Query: 299 RPVLTLR-SPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLS 357
P T R S + G+ +L + GS PI +Y ++ + +S + L
Sbjct: 8248 PPSFTKRLSETVEETEGNSFKLE-GRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 8306
Query: 358 LTAEHSGN-----YSCEANNGLG-AQCSEAVPV 384
L +G Y+C+ +N G A C+ ++ +
Sbjct: 8307 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVI 8339
Score = 45.8 bits (107), Expect = 9e-05
Identities = 93/394 (23%), Positives = 154/394 (39%), Gaps = 51/394 (12%)
Query: 13 VTEQADSLTLVAPSSVF-EGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQS 71
V E + V PS + G+S L C+ + + IQ + + K+NKELS + + S
Sbjct: 3733 VREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQ-VTWFKNNKELSESNTVRMYFVNS 3791
Query: 72 AVL--------SDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGP 123
+ DSG+Y C + D S + IK F + T + G
Sbjct: 3792 EAILDITDVKVEDSGSYSCEAVNDVGS-DSCSTEIVIKEPPSF---IKTLEPADIVRGTN 3847
Query: 124 VSLKCETRLSPQRLDVQLQFCFFRENQVLGSG-------WSSSPELQISAVWSEDTGSYW 176
L+CE + + +F++ + + S S L+I + S D G Y
Sbjct: 3848 ALLQCEVSGTGP-----FEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYE 3902
Query: 177 CKAETVTHRIRKQSLQSQIHVQRIPISNVSL--EIRAPGGQVTEGQKLILLCSVAGGTGN 234
C V + + K + H+ + P + V ++ A GGQ + L + G+
Sbjct: 3903 C---VVANEVGKCGCMAT-HLLKEPPTFVKKVDDLIALGGQT------VTLQAAVRGSEP 3952
Query: 235 VTFSWYREATGTSMGKKTQRSLS---AELEIPAVKESDAGKYYCRADNGHVPIQSKVVNI 291
++ +W + K + S S A L IP V+ S GKY C A+N Q+ V +
Sbjct: 3953 ISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAEN-EAGSQTSVGEL 4011
Query: 292 PVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNS-----SA 346
V+ P + R+ Q GD L + G+P + ++Y + L S S
Sbjct: 4012 IVKEPAK---IIERAELIQVTAGDPATLE-YTVAGTPELKPKWYKDGRPLVASKKYRISF 4067
Query: 347 PSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSE 380
+ S SG Y+ E +N +G+ E
Sbjct: 4068 KNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCE 4101
Score = 44.7 bits (104), Expect = 2e-04
Identities = 84/398 (21%), Positives = 150/398 (37%), Gaps = 62/398 (15%)
Query: 31 GDSIVLKCQGEQNWKIQKMAYHKDNKELSV------FKK-FSDFLIQSAVLSDSGNYFCS 83
G+ L+C+ + +I+ Y + K S FK + +I SD G Y C
Sbjct: 7034 GEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCK 7093
Query: 84 TKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIE---GGPVSLKCETRLSPQRLDVQ 140
+ +S ++ IK ++L P A + + G PV+ +C S
Sbjct: 7094 ADNSVGAV-ASSAVLVIKARKL---PPFFARKLKDVHETLGFPVAFECRINGSEP----- 7144
Query: 141 LQFCFFRENQVLGSGWSSSPE-------LQISAVWSEDTGSYWCKAETVTHRIRKQSLQS 193
LQ ++++ +L + LQI G Y C A S +
Sbjct: 7145 LQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTA-SSSAKL 7203
Query: 194 QIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQ 253
+ +P +++ + G+ C V G T + +W ++ G +
Sbjct: 7204 ILSEHEVP---PFFDLKPVSVDLALGESGTFKCHVTG-TAPIKITWAKDNREIRPGGNYK 7259
Query: 254 RSL---SAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRS--PG 308
+L +A L + V + DAG+Y C A N I K + ++ V P ++ P
Sbjct: 7260 MTLVENTATLTVLKVGKGDAGQYTCYASN----IAGKD-SCSAQLGVQEPPRFIKKLEPS 7314
Query: 309 AQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLS----------- 357
+ C+ + GSP I +Y ++ + SS F +S
Sbjct: 7315 RIVKQDEFTRYECK-IGGSPEIKVLWYKDETEIQESS-------KFRMSFVDSVAVLEMH 7366
Query: 358 -LTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRR 394
L+ E SG+Y+CEA+N G+ S + + + P +R+
Sbjct: 7367 NLSVEDSGDYTCEAHNAAGS-ASSSTSLKVKEPPIFRK 7403
Score = 43.9 bits (102), Expect = 3e-04
Identities = 83/402 (20%), Positives = 142/402 (35%), Gaps = 47/402 (11%)
Query: 13 VTEQADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKEL--------SVFKKF 64
V E A + P +V G++ L+C+ ++ + ++KD K L S + K
Sbjct: 5700 VLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELS-VEWYKDGKLLTSSQKHKFSFYNKI 5758
Query: 65 SDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTA--SSFQPIEGG 122
S I S D+G Y + + K+S + V + P T + + G
Sbjct: 5759 SSLRILSVERQDAGTYTFQVQNNV---GKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGA 5815
Query: 123 PVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPE-------LQISAVWSEDTGSY 175
L+C+ S + +F E + SG LQ++++ S D G+Y
Sbjct: 5816 SCILECKVAGSSP-----ISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNY 5870
Query: 176 WCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNV 235
C A V ++ + VQ P ++ P K + SV GT
Sbjct: 5871 TCVAANVA---GSDECRAVLTVQEPPSF-----VKEPEPLEVLPGKNVTFTSVIRGTPPF 5922
Query: 236 TFSWYREATGTSMGKKTQ---RSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIP 292
+W+R A G + AELE+ + S +G+Y C N + +
Sbjct: 5923 KVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSN-----NAGQASCT 5977
Query: 293 VRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGA 352
R+ V P L+ + + G+ PI + + + S +
Sbjct: 5978 TRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTT 6037
Query: 353 SFN-----LSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGP 389
L+ T +G YSCE N G A+ ++ P
Sbjct: 6038 EKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPP 6079
Score = 41.6 bits (96), Expect = 0.002
Identities = 43/154 (27%), Positives = 66/154 (42%), Gaps = 12/154 (7%)
Query: 238 SWYREAT--GTSMGKKTQRSLS---AELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIP 292
SW+R+ TS Q S S A+L IPAV ++++G+Y +A NG S +
Sbjct: 38 SWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATS-TAELL 96
Query: 293 VRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNS--SAPSGG 350
V+ + P R G + L + G P + +FY + + +S S
Sbjct: 97 VKAETAPPNFVQRLQSMTVRQGSQVRLQVR-VTGIPTPVVKFYRDGAEIQSSLDFQISQE 155
Query: 351 GASFNLSLT---AEHSGNYSCEANNGLGAQCSEA 381
G ++L + E SG YS A N +G S A
Sbjct: 156 GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTA 189
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/347 (21%), Positives = 129/347 (37%), Gaps = 38/347 (10%)
Query: 51 YHKDNKEL------SVFKKFSDFLIQ--SAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKV 102
+ KDNKEL SV+K + ++ +A +DSG Y C + + + +
Sbjct: 4801 WFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEP 4860
Query: 103 QELFQRP--VLTASSFQPIEGGPVSLKCETRLSPQ-RLDVQLQFCFFRENQVLGSGWSSS 159
+ ++P VL + G + +C+ +P+ R+ L Q G +
Sbjct: 4861 PQFIKKPSPVLVLRN-----GQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDG 4915
Query: 160 -PELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTE 218
QIS E++G+Y C+A + S ++ V+ P L+ +V +
Sbjct: 4916 LATFQISGARVENSGTYVCEAR---NDAGTASCSIELKVKEPPTFIRELK----PVEVVK 4968
Query: 219 GQKLILLCSVAGGTGNVTFSWYREATGTSMGKK---TQRSLSAELEIPAVKESDAGKYYC 275
+ L C V G T +W + KK T R L I SD G+Y C
Sbjct: 4969 YSDVELECEVTG-TPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQC 5027
Query: 276 RADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFY 335
N + + R+ + P ++ V + GSPPI +
Sbjct: 5028 IVSN-----EGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWL 5082
Query: 336 HEDVTLGNSS----APSGGGASFNL-SLTAEHSGNYSCEANNGLGAQ 377
+D L + A+ + S+ HSG Y+C+A N G +
Sbjct: 5083 KDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVE 5129
Score = 37.0 bits (84), Expect = 0.042
Identities = 64/270 (23%), Positives = 113/270 (41%), Gaps = 40/270 (14%)
Query: 49 MAYHKDNKELS-------VFKKFSDFL-IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKI 100
+A++K+N E+ FK + L ++ A ++D+G Y C TS+IV
Sbjct: 8281 VAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIV-- 8338
Query: 101 KVQELFQRPVLTASSFQPI---EGGPVSLKCETRLSPQRLDVQLQFC-----FFRENQVL 152
++E + PV P+ EG V L C + S +++Q+ ++
Sbjct: 8339 -IKEPKKPPVFD-QHLTPVTVSEGEYVQLSCHVQGSEP---IRIQWLKAGREIKPSDRCS 8393
Query: 153 GSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAP 212
S S + L++ V D+G Y CKA V + +S++ ++ P + + A
Sbjct: 8394 FSFASGTAVLELRDVAKADSGDYVCKASNVAG---SDTTKSKVTIKDKPAVAPATKKAAV 8450
Query: 213 GGQ---VTEGQKLILL-------CSVAGGTGNVTFSW----YREATGTSMGKKTQRSLSA 258
G+ V+E Q + ++ + GG W +R+ Q+ A
Sbjct: 8451 DGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEA 8510
Query: 259 ELEIPAVKESDAGKYYCRADNGHVPIQSKV 288
+LEI ++D+G Y C A N H I+S V
Sbjct: 8511 KLEIRDTTKTDSGLYRCVAFNEHGEIESNV 8540
Score = 36.6 bits (83), Expect = 0.055
Identities = 32/105 (30%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Query: 289 VNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNS---- 344
V PV IPV+ P L G+ + L C + G P +Y ED + +S
Sbjct: 932 VPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECH-ISGYPSPTVTWYREDYQIESSIDFQ 990
Query: 345 -SAPSGGGASFNLSLTAEHSGNYSCEANNGLG---AQCSEAVPVS 385
+ SG AE SG ++C A N G C AV VS
Sbjct: 991 ITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 1035
Score = 31.2 bits (69), Expect = 2.3
Identities = 40/147 (27%), Positives = 55/147 (37%), Gaps = 10/147 (6%)
Query: 257 SAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDL 316
S+ L IP V +D GKY +NG +S V++ V + P + + G +
Sbjct: 27326 SSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV---LDTPAACQKLQVKHVSRGTV 27382
Query: 317 LELHCEAL--RGSPPILYQFYHEDVTLGNSSAPSG--GGASFNLSLTAEHSGNY---SCE 369
L L GSP I Y D T S S SF L +E + + E
Sbjct: 27383 TLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 27442
Query: 370 ANNGLGAQCSEAVPVSISGPDGYRRDL 396
G+G C PV + RDL
Sbjct: 27443 NEIGIGEPCETTEPVKAAEVPAPIRDL 27469
Score = 30.8 bits (68), Expect = 3.0
Identities = 69/334 (20%), Positives = 126/334 (37%), Gaps = 49/334 (14%)
Query: 75 SDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSP 134
SDSG Y C+ K S+ K LT + + E VS + + ++P
Sbjct: 32917 SDSGLYTCTVKNSA---GSVSSSCK-----------LTIKAIKDTEAQKVSTQKTSEITP 32962
Query: 135 QRLDV---QLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSL 191
Q+ V ++ R ++ S S +L + ++ S +E V
Sbjct: 32963 QKKAVVQEEISQKALRSEEIKMSEAKSQEKLAL-----KEEASKVLISEEVKKSAATSLE 33017
Query: 192 QSQIHVQRIPISNVSLEIRAPGG--------QVTEGQKLILLCSVAGGTGNVTFSWYREA 243
+S +H + S S E+R + EGQ+L+L ++AG T W
Sbjct: 33018 KSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT---DVKWVLNG 33074
Query: 244 TGTSMGKKTQRSLSAELEIPAVKES---DAGKYYC--RADNGHVPIQSKVVNIPVRIPVS 298
+ ++ + +S + +K++ D G C + G V Q ++ + +S
Sbjct: 33075 VELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQ---YDLTLSKELS 33131
Query: 299 RPVLTLRSPGAQ-AAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLS 357
+ P +Q G + CE + G P +++ ++ + SS S + S
Sbjct: 33132 DAPAFISQPRSQNINEGQNVLFTCE-ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYS 33190
Query: 358 L-----TAEHSGNYSCEANNGLGAQCSEAVPVSI 386
L + SG Y+ +A N G QCS + +
Sbjct: 33191 LEIRNASVSDSGKYTIKAKNFRG-QCSATASLMV 33223
Score = 30.0 bits (66), Expect = 5.2
Identities = 36/149 (24%), Positives = 65/149 (43%), Gaps = 23/149 (15%)
Query: 15 EQADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDF------- 67
E+A +A V E D+I L C+ + ++ ++K ++E+ ++
Sbjct: 12461 EEAVFTKNLANIEVSETDTIKLVCEVSKPGA--EVIWYKGDEEIIETGRYEILTEGRKRI 12518
Query: 68 -LIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSL 126
+IQ+A L D+GNY C +T K+KV EL + + + +EG
Sbjct: 12519 LVIQNAHLEDAGNYNCRLPS-----SRTDG--KVKVHELAAEFISKPQNLEILEGEKAEF 12571
Query: 127 KCETRLSPQRLDVQLQFCFFRENQVLGSG 155
C +S + VQ + R+++ L SG
Sbjct: 12572 VCS--ISKESFPVQWK----RDDKTLESG 12594
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 71.6 bits (174), Expect = 2e-12
Identities = 70/241 (29%), Positives = 111/241 (46%), Gaps = 31/241 (12%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIH-VQRIP--ISNVSLEIRAPGGQVTE 218
L+I V D GSY C +T + + SQ++ + ++P ISN+S ++ V E
Sbjct: 96 LRIQKVDVYDEGSYTCSVQT-----QHEPKTSQVYLIVQVPPKISNISSDVT-----VNE 145
Query: 219 GQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRAD 278
G + L+C +A G +W R T T + + LEI + +GKY C+A
Sbjct: 146 GSNVTLVC-MANGRPEPVITW-RHLTPTGREFEGEEEY---LEILGITREQSGKYECKAA 200
Query: 279 NGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHED 338
N K V + V P P +T S +A G L CEA P +++Y +D
Sbjct: 201 NEVSSADVKQVKVTVNYP---PTIT-ESKSNEATTGRQASLKCEASAVPAPD-FEWYRDD 255
Query: 339 VTLGNSSA----PSGGGASFNLS-LTAEHSGNYSCEANNGLGAQCSEAV---PVSISGPD 390
+ +++ + G +S ++ +T EH GNY+C A N LG + V P S+ G +
Sbjct: 256 TRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFRPGSVRGIN 315
Query: 391 G 391
G
Sbjct: 316 G 316
Score = 39.3 bits (90), Expect = 0.009
Identities = 50/203 (24%), Positives = 76/203 (37%), Gaps = 24/203 (11%)
Query: 200 IPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGK--------- 250
+P+ +V V +G IL C V V +W + G
Sbjct: 27 LPVRSVDFNRGTDNITVRQGDTAILRCVVEDKNSKV--AWLNRSGIIFAGHDKWSLDPRV 84
Query: 251 --KTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPG 308
+ + SL L I V D G Y C H P S+V I V++P P ++ S
Sbjct: 85 ELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLI-VQVP---PKISNISSD 140
Query: 309 AQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASF--NLSLTAEHSGNY 366
G + L C A G P + + H L + G + L +T E SG Y
Sbjct: 141 VTVNEGSNVTLVCMA-NGRPEPVITWRH----LTPTGREFEGEEEYLEILGITREQSGKY 195
Query: 367 SCEANNGLGAQCSEAVPVSISGP 389
C+A N + + + V V+++ P
Sbjct: 196 ECKAANEVSSADVKQVKVTVNYP 218
Score = 29.3 bits (64), Expect = 8.8
Identities = 29/144 (20%), Positives = 54/144 (37%), Gaps = 33/144 (22%)
Query: 77 SGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQR 136
SG Y C ++ ++++ ++KV + + + S + G SLKCE P
Sbjct: 192 SGKYECKAANEV----SSADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAP 247
Query: 137 LDVQLQFCFFRENQVLGS-------GWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQ 189
F ++R++ + S L ++ V E G+Y C A
Sbjct: 248 -----DFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVA---------- 292
Query: 190 SLQSQIHVQRIPISNVSLEIRAPG 213
++ ++N SL + PG
Sbjct: 293 -------ANKLGVTNASLVLFRPG 309
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 69.3 bits (168), Expect = 8e-12
Identities = 88/360 (24%), Positives = 150/360 (41%), Gaps = 30/360 (8%)
Query: 31 GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFL------IQSAVLSDSGNYFCST 84
GD VL C+ + + + ++KD + L + ++ IQ A +SD G Y C
Sbjct: 1856 GDKAVLSCETDALPE-PTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKV 1914
Query: 85 KGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFC 144
+T + ++V F+ P + + G P+ L C+ P L+
Sbjct: 1915 SNVAGEAVRTFTLT-VQVPPTFENP--KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDR 1971
Query: 145 FFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISN 204
E+ + S LQ+S + G+Y C AE RK + + + RI S
Sbjct: 1972 MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSG 2031
Query: 205 VSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREAT--GTSMGKKTQRSL-SAELE 261
V+ E V EGQ++ L C A G +W ++ + G MG + L L
Sbjct: 2032 VARE-----HHVLEGQEVRLDCE-ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLV 2085
Query: 262 IPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAV---GDLLE 318
+ ++ SDAG Y C A N +++ + V +P P + + G+ V G+L+
Sbjct: 2086 LKGLRASDAGAYTCVAHN-PAGEDARLHTVNVLVP---PTIKQGADGSGTLVSRPGELVT 2141
Query: 319 LHCEALRGSPPILYQFYHEDVTLGNSSAP--SGGGASFNLS-LTAEHSGNYSCEANNGLG 375
+ C +RGSPPI + + + L S G G + +S + +G ++C A + G
Sbjct: 2142 MVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAG 2200
Score = 62.0 bits (149), Expect = 1e-09
Identities = 76/334 (22%), Positives = 132/334 (39%), Gaps = 38/334 (11%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKC 128
I L+D+G + C + D+ + +++V + + PV + + G V L C
Sbjct: 2180 ISKVQLADAGIFTCVAASPAGVADRNFTL-QVQVPPVLE-PVEFQNDVVVVRGSLVELPC 2237
Query: 129 ETRLSPQRLDVQLQFCFFRENQ-VLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIR 187
E R P L + ++ + +L P LQ+ AV + D+G+Y C A + R
Sbjct: 2238 EARGVPLPL-----VSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 2292
Query: 188 KQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTS 247
+ + + I S E+ +T G + LLC A GT +W+++ +
Sbjct: 2293 RHFQLTVMEPPHIEDSGQPTEL-----SLTPGAPMELLCD-AQGTPQPNITWHKDGQALT 2346
Query: 248 MGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSP 307
+ R+ ++ DAG Y C A++ I+ R+ V P +
Sbjct: 2347 RLENNSRATR------VLRVRDAGLYTCLAESPAGAIEKS-----FRVRVQAPPNIVGPR 2395
Query: 308 GAQAAVG---DLLELHCEALRGSPPILYQFYHEDVTL---GNSSAPSGGGASFNLSLTAE 361
G + VG L L C ++ P ++ + + L ++ P G +L+
Sbjct: 2396 GPRFVVGLAPGQLVLEC-SVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTA 2454
Query: 362 HSGNYSCEANNGLGAQC------SEAVPVSISGP 389
SG+YSC A N G+ VP SGP
Sbjct: 2455 DSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGP 2488
Score = 60.8 bits (146), Expect = 3e-09
Identities = 82/351 (23%), Positives = 137/351 (39%), Gaps = 39/351 (11%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSF------------ 116
IQ +SDSG Y C D+ N++ I+V +FQ+ +++F
Sbjct: 1506 IQPTQVSDSGRYLCVATNVAGEDDQDFNVL-IQVPPMFQKVGDFSAAFEILSREEEARGG 1564
Query: 117 -----QPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSG-----WSSSPELQISA 166
+ +E P L C+T P ++RE+Q L +G LQI
Sbjct: 1565 VTEYREIVENNPAYLYCDTNAIPPP-----DLTWYREDQPLSAGDEVSVLQGGRVLQIPL 1619
Query: 167 VWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLC 226
V +E+ G Y CKA ++ + + L ++ V P+ E V + L C
Sbjct: 1620 VRAENAGRYSCKA---SNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQC 1676
Query: 227 SVAGGTGNVTFSWYREATGTSMGKKTQRSLSAE-LEIPAVKESDAGKYYCRADNGHVPIQ 285
A G T SW + S + Q + L++ + +DA Y C A+N
Sbjct: 1677 P-ALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAEN-QAGSA 1734
Query: 286 SKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEA-LRGSPPILYQFYHEDVTLGNS 344
K+ + V++P L L A + + L C+ +P + + + ++LG
Sbjct: 1735 EKLFTLRVQVPPRIAGLDLEQ--VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEE 1792
Query: 345 SAPSGGGASFNLS-LTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRR 394
G + L SG Y+CEA N G + V +S+ P +R+
Sbjct: 1793 VFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRD-QKLVQLSVLVPPAFRQ 1842
Score = 58.5 bits (140), Expect = 1e-08
Identities = 68/229 (29%), Positives = 99/229 (43%), Gaps = 22/229 (9%)
Query: 150 QVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEI 209
QVL G +L+I+ ED G+Y C A+ ++ ++ VQ P+ +E
Sbjct: 2804 QVLPGG-----QLRIAHASPEDAGNYLCIAKNSAGSAMGKT---RLVVQVPPV----IEN 2851
Query: 210 RAPGGQVTEGQKLILLCSVAGGTG-NVTFSWYREATGTSMGKKTQRSLSAELEIPAVKES 268
P TEG L C G N+T+ + + GK T + S EL + ++
Sbjct: 2852 GLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQP-SGELLVKNLEGQ 2910
Query: 269 DAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSP 328
DAG Y C A+N V + V++ + + PV T +GD L L C A RGSP
Sbjct: 2911 DAGTYTCTAENA-VGRARRRVHLTILV---LPVFTTLPGDRSLRLGDRLWLRCAA-RGSP 2965
Query: 329 P--ILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLG 375
I + VT G S GG +++ E SG Y C A N +G
Sbjct: 2966 TPRIGWTVNDRPVTEGVSEQ-DGGSTLQRAAVSREDSGTYVCWAENRVG 3013
Score = 57.4 bits (137), Expect = 3e-08
Identities = 63/238 (26%), Positives = 92/238 (38%), Gaps = 38/238 (15%)
Query: 153 GSGWSSSPE--LQISAVWSEDTGSYWCKAET---VTHRIRKQSLQSQIHVQRIPISNVSL 207
GSG+ SP L+I G Y C A V H+ ++Q+ V+ +P
Sbjct: 2710 GSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSV---- 2765
Query: 208 EIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKE 267
+RA ++ +LL A G T +W +E + G TQ +L I
Sbjct: 2766 -VRAVA------EEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASP 2818
Query: 268 SDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGS 327
DAG Y C A N K + V++P PV+ P G L C+A RGS
Sbjct: 2819 EDAGNYLCIAKNSAGSAMGK-TRLVVQVP---PVIENGLPDLSTTEGSHAFLPCKA-RGS 2873
Query: 328 PPILYQFYHEDVTLGNSSAP-SGGGASFNL---------SLTAEHSGNYSCEANNGLG 375
P ++T P SG F + +L + +G Y+C A N +G
Sbjct: 2874 P-------EPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG 2924
Score = 56.2 bits (134), Expect = 7e-08
Identities = 86/378 (22%), Positives = 146/378 (38%), Gaps = 37/378 (9%)
Query: 27 SVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELS------VFKKFSDFLIQSAVLSDSGNY 80
S EG L C+ + + + + KD + +S + + L+++ D+G Y
Sbjct: 2857 STTEGSHAFLPCKARGSPE-PNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTY 2915
Query: 81 FCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTA--SSFQPIEGGPVSLKCETRLSPQ-RL 137
C+ + + + V + + L PV T G + L+C R SP R+
Sbjct: 2916 TCTAENAV---GRARRRVHLTILVL---PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRI 2969
Query: 138 DVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHV 197
+ E G S+ LQ +AV ED+G+Y C AE +R+ + S +HV
Sbjct: 2970 GWTVNDRPVTEGVSEQDGGST---LQRAAVSREDSGTYVCWAE---NRVGRTQAVSFVHV 3023
Query: 198 QRIPI---SNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQR 254
+ P+ S + GG I L V G W ++ +
Sbjct: 3024 KEAPVLQGEAFSYLVEPVGGS-------IQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQ 3076
Query: 255 SLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVG 314
+ L I + DAG+Y C A+N + + KVV + + S PV + G
Sbjct: 3077 LQNGSLTIHRTERDDAGRYQCLAEN-EMGVAKKVV---ILVLQSAPVFQVEPQDMTVRSG 3132
Query: 315 DLLELHCEAL-RGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNG 373
D + L C+A +P I + + + G+ + ++ +G Y C A+N
Sbjct: 3133 DDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNL 3192
Query: 374 LGAQCSEAVPVSISGPDG 391
LG+ + A V P G
Sbjct: 3193 LGSATARAFLVVRGEPQG 3210
Score = 55.1 bits (131), Expect = 2e-07
Identities = 65/240 (27%), Positives = 96/240 (40%), Gaps = 29/240 (12%)
Query: 161 ELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGG-----Q 215
+LQ+ S D G Y CKA K + R+ + V I GG +
Sbjct: 366 QLQLGRAQSSDAGVYTCKASNAVGAAEKAT--------RLDV-YVPPTIEGAGGRPYVVK 416
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAE---LEIPAVKESDAGK 272
G+ + L C VA G + T SW+ E G + + + L + L + + E+ +G
Sbjct: 417 AVAGRPVALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGL 473
Query: 273 YYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPG-AQAAVGDLLELHCEALRGSPPIL 331
Y C A + P V+ V + V +L G VG LEL C+A GSP
Sbjct: 474 YSCVASS---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQA-SGSPVPT 529
Query: 332 YQFYHED---VTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISG 388
Q+ L S G + +HSG ++C+A N G +E V VS+ G
Sbjct: 530 IQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAE-VEVSVHG 588
Score = 50.1 bits (118), Expect = 5e-06
Identities = 62/222 (27%), Positives = 91/222 (40%), Gaps = 20/222 (9%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPI---SNVSLEIRAPGGQVTE 218
L+I+ D G Y C A + + Q+ Q+ V P SN + E+ V E
Sbjct: 274 LRITGSHVGDEGRYQCVAFSPAGQ---QARDFQLRVHAPPTIWGSNETGEVA-----VME 325
Query: 219 GQKLILLCSVAG-GTGNVTFSWYREATGTSMGKKTQRSLSA-ELEIPAVKESDAGKYYCR 276
+ LLC G T N+T W+++ K + +L++ + SDAG Y C+
Sbjct: 326 DHLVQLLCEARGVPTPNIT--WFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCK 383
Query: 277 ADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYH 336
A N V K + V +P + R +A G + L C A RG P ++H
Sbjct: 384 ASNA-VGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVA-RGHPSPTLSWHH 441
Query: 337 E--DVTLGNSSAPSGGGASFNLSLTAE-HSGNYSCEANNGLG 375
E V N S G+ L E SG YSC A++ G
Sbjct: 442 EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAG 483
Score = 46.6 bits (109), Expect = 5e-05
Identities = 71/255 (27%), Positives = 97/255 (38%), Gaps = 41/255 (16%)
Query: 156 WSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQ 215
+S P LQI V D G Y C A + +S+ V + ++E
Sbjct: 653 YSLPPPLQIEKVDLRDEGIYTCAATNLAG-------ESKREVALKVLVPPNIEPGPVNKA 705
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAE-LEIPAVKESDAGKYY 274
V E + L C +A G SW++ S S+ L I + SDAG Y
Sbjct: 706 VLENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 764
Query: 275 CRADN--GHVPIQSKV-VNIPVRI--PVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPP 329
C A N G ++ + VN+P RI P S P V + L C A P
Sbjct: 765 CVASNVAGSTELRYGLRVNVPPRITLPPSLP--------GPVLVNTPVRLTCNATGAPSP 816
Query: 330 ILYQFYHEDVTLGNSSAPSG--------GGASFNL-SLTAEHSGNYSCEANNGLGAQCSE 380
L + +D GN +P+G GG L S A SG YSC A + +G +
Sbjct: 817 TL--MWLKD---GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD 871
Query: 381 AV-----PVSISGPD 390
V P SI G +
Sbjct: 872 VVLQVHMPPSILGEE 886
Score = 42.7 bits (99), Expect = 8e-04
Identities = 60/242 (24%), Positives = 98/242 (40%), Gaps = 38/242 (15%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQV----- 216
LQI ED G Y C VT+ + + + V P S+ P G+V
Sbjct: 1406 LQILNAQKEDAGQYTC---VVTNELGEAVKNYHVEVLIPP----SISKDDPLGEVGVKEV 1458
Query: 217 -TEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAEL-EIPAVKESDAGKYY 274
T+ + L + T WY++ + + Q L +I + SD+G+Y
Sbjct: 1459 KTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYL 1518
Query: 275 CRADNGHVPIQSKVVNIPVRIP----------VSRPVLTLRSPGAQAAVGDLLE------ 318
C A N + N+ +++P + +L+ R A+ V + E
Sbjct: 1519 CVATNV-AGEDDQDFNVLIQVPPMFQKVGDFSAAFEILS-REEEARGGVTEYREIVENNP 1576
Query: 319 --LHCEALRGSPPILYQFYHEDVTL--GNSSAPSGGGASFNLSLT-AEHSGNYSCEANNG 373
L+C+ PP L +Y ED L G+ + GG + L AE++G YSC+A+N
Sbjct: 1577 AYLYCDTNAIPPPDL-TWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNE 1635
Query: 374 LG 375
+G
Sbjct: 1636 VG 1637
Score = 42.7 bits (99), Expect = 8e-04
Identities = 79/326 (24%), Positives = 120/326 (36%), Gaps = 48/326 (14%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRP---VLTASSFQPIEGGPVS 125
IQ + D+G+Y C + ++ ++ + P LTA + P
Sbjct: 2539 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHT-------PAL 2591
Query: 126 LKCETRLSP----------QRLDVQLQFCFFR---ENQVLGSGWSSSPELQISAVWSEDT 172
L CE SP Q+LD +LQ +R N +L + Q V S +
Sbjct: 2592 LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEV 2651
Query: 173 GSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGT 232
G HR+ Q +HV I++ + VT ++L C + G
Sbjct: 2652 GE--------AHRL----YQVTVHVPPT-IADDQTDFT-----VTMMAPVVLTCH-STGI 2692
Query: 233 GNVTFSWYREATGT-SMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNI 291
T SW + + G + S S LEI AG+Y C A N V
Sbjct: 2693 PAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLT 2752
Query: 292 PVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALR-GSPPILYQFYHEDVTLGNSSAPSGG 350
PV +P+ ++ +A + + L CEA P I +Q +V G S+ G
Sbjct: 2753 VQASPVVKPLPSV----VRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG 2808
Query: 351 GASFNLSLTAEHSGNYSCEANNGLGA 376
G + E +GNY C A N G+
Sbjct: 2809 GQLRIAHASPEDAGNYLCIAKNSAGS 2834
Score = 40.4 bits (93), Expect = 0.004
Identities = 75/326 (23%), Positives = 117/326 (35%), Gaps = 49/326 (15%)
Query: 72 AVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQEL---FQRPVLTASSFQP------IEGG 122
A L+ G Y C + SN+V Q+L P A +P ++ G
Sbjct: 1034 AQLAQEGTYTC----------ECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDG 1083
Query: 123 PVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGW-----SSSPELQISAVWSEDTGSYWC 177
+L+C P + R+ Q +G+ + L + + TG Y C
Sbjct: 1084 VATLECNATGKPPPT-----VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSC 1138
Query: 178 KAETVTHRI-RKQSLQSQIHVQRI----PISNVSLEIRAPGGQVTEGQKLILLCSVAGGT 232
AE + R RK L + + I P++N++ + +P L LLC A G
Sbjct: 1139 VAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSP---------LTLLCE-AMGI 1188
Query: 233 GNVTFSWYREATGTSMGKKTQRSLSA-ELEIPAVKESDAGKYYCRADNGHVPIQSKVVNI 291
W+R S G+ T L++ +E D+G Y C A N + ++
Sbjct: 1189 PPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASN-EAGEARRNFSV 1247
Query: 292 PVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYH-EDVTLGNSSAPSGG 350
V +P S L + G L C P L F + G++ S
Sbjct: 1248 EVLVPPSIENEDLEEV-IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD 1306
Query: 351 GASFN-LSLTAEHSGNYSCEANNGLG 375
G L +G+YSC A N +G
Sbjct: 1307 GVLLQVLQANLSSAGHYSCIAANAVG 1332
Score = 38.9 bits (89), Expect = 0.011
Identities = 42/145 (28%), Positives = 56/145 (38%), Gaps = 21/145 (14%)
Query: 150 QVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHV----QRIPISNV 205
QVLG G LQI D+G Y C A V Q I V Q++ +
Sbjct: 1496 QVLGEGRL----LQIQPTQVSDSGRYLCVATNVAGE-DDQDFNVLIQVPPMFQKVGDFSA 1550
Query: 206 SLEI-----RAPGG-----QVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRS 255
+ EI A GG ++ E L C +WYRE S G +
Sbjct: 1551 AFEILSREEEARGGVTEYREIVENNPAYLYCDT-NAIPPPDLTWYREDQPLSAGDEVSVL 1609
Query: 256 LSAE-LEIPAVKESDAGKYYCRADN 279
L+IP V+ +AG+Y C+A N
Sbjct: 1610 QGGRVLQIPLVRAENAGRYSCKASN 1634
Score = 35.0 bits (79), Expect = 0.16
Identities = 82/346 (23%), Positives = 128/346 (36%), Gaps = 52/346 (15%)
Query: 69 IQSAVLSDSGNYFCSTKG-----QLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGP 123
I+ A LSD+G+Y C +L + + +I + PVL + P
Sbjct: 752 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNT--------P 803
Query: 124 VSLKCETRLSPQRLDVQLQFCFFRENQVLGSG------WSSSPELQISAVWSEDTGSYWC 177
V L C +P + L+ N V +G + L +++ + D+G Y C
Sbjct: 804 VRLTCNATGAPSPTLMWLK----DGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC 859
Query: 178 KAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTF 237
A + R Q + Q+H +P S + E+ V + + L C +
Sbjct: 860 VAVSAVGEDR-QDVVLQVH---MPPSILGEELNV---SVVANESVALECQ-SHAMPPPVL 911
Query: 238 SWYREATGTSMGKKTQRSLSAE---LEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVR 294
SW+++ G + + LSA+ L++ DAG Y C A N K N+ V
Sbjct: 912 SWWKD--GRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALN-QAGRSEKHYNLNVW 968
Query: 295 IPVSRPVLTLR-SPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTL-----GNSSAPS 348
+ PV LR S G L CE RG P + + L G +
Sbjct: 969 V---APVFPLRESHTLTVREGHPTSLSCEC-RGVPFPKISWRKDGQPLPGEGAGLQHVSA 1024
Query: 349 GGGASFNLSLTAEHSGNYSCEANNGLG-----AQCSEAVPVSISGP 389
G + G Y+CE +N +G Q VP I+GP
Sbjct: 1025 VGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGP 1070
Score = 34.3 bits (77), Expect = 0.28
Identities = 79/350 (22%), Positives = 122/350 (34%), Gaps = 71/350 (20%)
Query: 58 LSVFKKFSDFLIQSAVLSDSGNYFC---STKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
L VF + SA SDSG Y C S G+ D+ ++++ + L S
Sbjct: 835 LQVFPGGRVLTLASARASDSGRYSCVAVSAVGE----DRQDVVLQVHMPPSILGEELNVS 890
Query: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISA-------- 166
+ V+L+C++ P + ++++ + L P + +SA
Sbjct: 891 V---VANESVALECQSHAMPPPV-----LSWWKDGRPL----EPRPGVHLSADKALLQVD 938
Query: 167 ---VWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLI 223
VW D G Y C+A R K ++V P+ + + V EG
Sbjct: 939 RADVW--DAGHYTCEALNQAGRSEKHY---NLNVWVAPVFPLR---ESHTLTVREGHPTS 990
Query: 224 LLCSVAGGTGNVTF---SWYREAT---GTSMGKKTQRSLSAELEIPAVKESDAGKYYCRA 277
L C G V F SW ++ G G + ++ L + + + G Y C
Sbjct: 991 LSCECRG----VPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCEC 1046
Query: 278 DNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAV--GDLLELHCEALRGSPPILYQFY 335
N V S+ + + V +P + R P Q +V + L C A PP
Sbjct: 1047 SNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATLECNATGKPPPT----- 1098
Query: 336 HEDVTLGNSSAPSGGGASFNLS----------LTAEHSGNYSCEANNGLG 375
VT P G L A H+G YSC A N G
Sbjct: 1099 ---VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAG 1145
Score = 33.9 bits (76), Expect = 0.36
Identities = 30/119 (25%), Positives = 45/119 (37%), Gaps = 9/119 (7%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQK 221
LQ+ A+ + D+G Y C A S+ ++ + +P ++ P V+ Q
Sbjct: 2446 LQLQALSTADSGDYSCTARNAAG---STSVAFRVEIHTVP----TIRSGPPAVNVSVNQT 2498
Query: 222 LILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSL-SAELEIPAVKESDAGKYYCRADN 279
+L C A G SW ++ L L I V DAG Y C A N
Sbjct: 2499 ALLPCQ-ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN 2556
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 69.3 bits (168), Expect = 8e-12
Identities = 88/360 (24%), Positives = 150/360 (41%), Gaps = 30/360 (8%)
Query: 31 GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFL------IQSAVLSDSGNYFCST 84
GD VL C+ + + + ++KD + L + ++ IQ A +SD G Y C
Sbjct: 3047 GDKAVLSCETDALPE-PTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKV 3105
Query: 85 KGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFC 144
+T + ++V F+ P + + G P+ L C+ P L+
Sbjct: 3106 SNVAGEAVRTFTLT-VQVPPTFENP--KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDR 3162
Query: 145 FFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISN 204
E+ + S LQ+S + G+Y C AE RK + + + RI S
Sbjct: 3163 MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSG 3222
Query: 205 VSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREAT--GTSMGKKTQRSL-SAELE 261
V+ E V EGQ++ L C A G +W ++ + G MG + L L
Sbjct: 3223 VARE-----HHVLEGQEVRLDCE-ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLV 3276
Query: 262 IPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAV---GDLLE 318
+ ++ SDAG Y C A N +++ + V +P P + + G+ V G+L+
Sbjct: 3277 LKGLRASDAGAYTCVAHN-PAGEDARLHTVNVLVP---PTIKQGADGSGTLVSRPGELVT 3332
Query: 319 LHCEALRGSPPILYQFYHEDVTLGNSSAP--SGGGASFNLS-LTAEHSGNYSCEANNGLG 375
+ C +RGSPPI + + + L S G G + +S + +G ++C A + G
Sbjct: 3333 MVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAG 3391
Score = 62.0 bits (149), Expect = 1e-09
Identities = 76/334 (22%), Positives = 132/334 (39%), Gaps = 38/334 (11%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKC 128
I L+D+G + C + D+ + +++V + + PV + + G V L C
Sbjct: 3371 ISKVQLADAGIFTCVAASPAGVADRNFTL-QVQVPPVLE-PVEFQNDVVVVRGSLVELPC 3428
Query: 129 ETRLSPQRLDVQLQFCFFRENQ-VLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIR 187
E R P L + ++ + +L P LQ+ AV + D+G+Y C A + R
Sbjct: 3429 EARGVPLPL-----VSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 3483
Query: 188 KQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTS 247
+ + + I S E+ +T G + LLC A GT +W+++ +
Sbjct: 3484 RHFQLTVMEPPHIEDSGQPTEL-----SLTPGAPMELLCD-AQGTPQPNITWHKDGQALT 3537
Query: 248 MGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSP 307
+ R+ ++ DAG Y C A++ I+ R+ V P +
Sbjct: 3538 RLENNSRATR------VLRVRDAGLYTCLAESPAGAIEKS-----FRVRVQAPPNIVGPR 3586
Query: 308 GAQAAVG---DLLELHCEALRGSPPILYQFYHEDVTL---GNSSAPSGGGASFNLSLTAE 361
G + VG L L C ++ P ++ + + L ++ P G +L+
Sbjct: 3587 GPRFVVGLAPGQLVLEC-SVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTA 3645
Query: 362 HSGNYSCEANNGLGAQC------SEAVPVSISGP 389
SG+YSC A N G+ VP SGP
Sbjct: 3646 DSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGP 3679
Score = 60.8 bits (146), Expect = 3e-09
Identities = 82/351 (23%), Positives = 137/351 (39%), Gaps = 39/351 (11%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSF------------ 116
IQ +SDSG Y C D+ N++ I+V +FQ+ +++F
Sbjct: 2697 IQPTQVSDSGRYLCVATNVAGEDDQDFNVL-IQVPPMFQKVGDFSAAFEILSREEEARGG 2755
Query: 117 -----QPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSG-----WSSSPELQISA 166
+ +E P L C+T P ++RE+Q L +G LQI
Sbjct: 2756 VTEYREIVENNPAYLYCDTNAIPPP-----DLTWYREDQPLSAGDEVSVLQGGRVLQIPL 2810
Query: 167 VWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLC 226
V +E+ G Y CKA ++ + + L ++ V P+ E V + L C
Sbjct: 2811 VRAENAGRYSCKA---SNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQC 2867
Query: 227 SVAGGTGNVTFSWYREATGTSMGKKTQRSLSAE-LEIPAVKESDAGKYYCRADNGHVPIQ 285
A G T SW + S + Q + L++ + +DA Y C A+N
Sbjct: 2868 P-ALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAEN-QAGSA 2925
Query: 286 SKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEA-LRGSPPILYQFYHEDVTLGNS 344
K+ + V++P L L A + + L C+ +P + + + ++LG
Sbjct: 2926 EKLFTLRVQVPPRIAGLDLEQ--VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEE 2983
Query: 345 SAPSGGGASFNLS-LTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRR 394
G + L SG Y+CEA N G + V +S+ P +R+
Sbjct: 2984 VFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRD-QKLVQLSVLVPPAFRQ 3033
Score = 58.5 bits (140), Expect = 1e-08
Identities = 68/229 (29%), Positives = 99/229 (43%), Gaps = 22/229 (9%)
Query: 150 QVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEI 209
QVL G +L+I+ ED G+Y C A+ ++ ++ VQ P+ +E
Sbjct: 3995 QVLPGG-----QLRIAHASPEDAGNYLCIAKNSAGSAMGKT---RLVVQVPPV----IEN 4042
Query: 210 RAPGGQVTEGQKLILLCSVAGGTG-NVTFSWYREATGTSMGKKTQRSLSAELEIPAVKES 268
P TEG L C G N+T+ + + GK T + S EL + ++
Sbjct: 4043 GLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQP-SGELLVKNLEGQ 4101
Query: 269 DAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSP 328
DAG Y C A+N V + V++ + + PV T +GD L L C A RGSP
Sbjct: 4102 DAGTYTCTAENA-VGRARRRVHLTILV---LPVFTTLPGDRSLRLGDRLWLRCAA-RGSP 4156
Query: 329 P--ILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLG 375
I + VT G S GG +++ E SG Y C A N +G
Sbjct: 4157 TPRIGWTVNDRPVTEGVSEQ-DGGSTLQRAAVSREDSGTYVCWAENRVG 4204
Score = 57.4 bits (137), Expect = 3e-08
Identities = 63/238 (26%), Positives = 92/238 (38%), Gaps = 38/238 (15%)
Query: 153 GSGWSSSPE--LQISAVWSEDTGSYWCKAET---VTHRIRKQSLQSQIHVQRIPISNVSL 207
GSG+ SP L+I G Y C A V H+ ++Q+ V+ +P
Sbjct: 3901 GSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSV---- 3956
Query: 208 EIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKE 267
+RA ++ +LL A G T +W +E + G TQ +L I
Sbjct: 3957 -VRAVA------EEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASP 4009
Query: 268 SDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGS 327
DAG Y C A N K + V++P PV+ P G L C+A RGS
Sbjct: 4010 EDAGNYLCIAKNSAGSAMGK-TRLVVQVP---PVIENGLPDLSTTEGSHAFLPCKA-RGS 4064
Query: 328 PPILYQFYHEDVTLGNSSAP-SGGGASFNL---------SLTAEHSGNYSCEANNGLG 375
P ++T P SG F + +L + +G Y+C A N +G
Sbjct: 4065 P-------EPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG 4115
Score = 56.2 bits (134), Expect = 7e-08
Identities = 86/378 (22%), Positives = 146/378 (38%), Gaps = 37/378 (9%)
Query: 27 SVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELS------VFKKFSDFLIQSAVLSDSGNY 80
S EG L C+ + + + + KD + +S + + L+++ D+G Y
Sbjct: 4048 STTEGSHAFLPCKARGSPE-PNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTY 4106
Query: 81 FCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTA--SSFQPIEGGPVSLKCETRLSPQ-RL 137
C+ + + + V + + L PV T G + L+C R SP R+
Sbjct: 4107 TCTAENAV---GRARRRVHLTILVL---PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRI 4160
Query: 138 DVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHV 197
+ E G S+ LQ +AV ED+G+Y C AE +R+ + S +HV
Sbjct: 4161 GWTVNDRPVTEGVSEQDGGST---LQRAAVSREDSGTYVCWAE---NRVGRTQAVSFVHV 4214
Query: 198 QRIPI---SNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQR 254
+ P+ S + GG I L V G W ++ +
Sbjct: 4215 KEAPVLQGEAFSYLVEPVGGS-------IQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQ 4267
Query: 255 SLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVG 314
+ L I + DAG+Y C A+N + + KVV + + S PV + G
Sbjct: 4268 LQNGSLTIHRTERDDAGRYQCLAEN-EMGVAKKVV---ILVLQSAPVFQVEPQDMTVRSG 4323
Query: 315 DLLELHCEAL-RGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNG 373
D + L C+A +P I + + + G+ + ++ +G Y C A+N
Sbjct: 4324 DDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNL 4383
Query: 374 LGAQCSEAVPVSISGPDG 391
LG+ + A V P G
Sbjct: 4384 LGSATARAFLVVRGEPQG 4401
Score = 55.8 bits (133), Expect = 9e-08
Identities = 84/327 (25%), Positives = 123/327 (37%), Gaps = 39/327 (11%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKC 128
I + +D G Y C + T V + V+E Q + T+S +G V + C
Sbjct: 574 ISGIIPTDGGRYQCVASNANGV---TRASVWLLVREAPQVSIHTSSQHFS-QGVEVKVSC 629
Query: 129 ETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQ----ISAVWSEDTGSYWCKAETVTH 184
P + RE+Q L + Q I V ED G+Y C+A T+
Sbjct: 630 SASGYPTP-----HISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA---TN 681
Query: 185 RIRKQSLQSQIHVQRIP-ISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREA 243
+ ++ P +S V+ + V G++ +L+C A G WYR
Sbjct: 682 EVGTDQETVTLYYTDPPSVSAVNAVVL-----VAVGEEAVLVCE-ASGVPPPRVIWYRG- 734
Query: 244 TGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSR-PVL 302
G M + S S +L IPA +E DAG Y CRA N + + +++ V P L
Sbjct: 735 -GLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVN-----ELGDASAEIQLAVGHAPQL 788
Query: 303 TLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTL--------GNSSAPSGGGASF 354
T +G L C A PP + + L G+ S G F
Sbjct: 789 TELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLF 848
Query: 355 NLSLTAEHSGNYSCEANNGLGAQCSEA 381
S+ E Y CEA N G +EA
Sbjct: 849 FESVAPEDQAPYVCEARNVFGKVQAEA 875
Score = 55.1 bits (131), Expect = 2e-07
Identities = 65/240 (27%), Positives = 96/240 (40%), Gaps = 29/240 (12%)
Query: 161 ELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQ----- 215
+LQ+ S D G Y CKA K + R+ + V I GG+
Sbjct: 1557 QLQLGRAQSSDAGVYTCKASNAVGAAEKAT--------RLDVY-VPPTIEGAGGRPYVVK 1607
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAE---LEIPAVKESDAGK 272
G+ + L C VA G + T SW+ E G + + + L + L + + E+ +G
Sbjct: 1608 AVAGRPVALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGL 1664
Query: 273 YYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPG-AQAAVGDLLELHCEALRGSPPIL 331
Y C A + P V+ V + V +L G VG LEL C+A GSP
Sbjct: 1665 YSCVASS---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQA-SGSPVPT 1720
Query: 332 YQFYHED---VTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISG 388
Q+ L S G + +HSG ++C+A N G +E V VS+ G
Sbjct: 1721 IQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAE-VEVSVHG 1779
Score = 52.4 bits (124), Expect = 1e-06
Identities = 82/315 (26%), Positives = 125/315 (39%), Gaps = 35/315 (11%)
Query: 76 DSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPI---EGGPVSLKCETRL 132
DSG Y C + Q + +++ + VL A + Q + G V L+C T
Sbjct: 1380 DSGLYSCRAENQAGTAQRDFHLLVLTPPS-----VLGAGAAQEVLGLAGADVELQCWTSG 1434
Query: 133 SPQRLDVQLQFCFFRENQVLGSGWSSSPE----LQISAVWSEDTGSYWCKAETVTHRIRK 188
P Q+++ R+ + G E L+I+ D G Y C A + +
Sbjct: 1435 VPTP---QVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQ--- 1488
Query: 189 QSLQSQIHVQRIPI---SNVSLEIRAPGGQVTEGQKLILLCSVAG-GTGNVTFSWYREAT 244
Q+ Q+ V P SN + E+ V E + LLC G T N+T W+++
Sbjct: 1489 QARDFQLRVHAPPTIWGSNETGEVA-----VMEDHLVQLLCEARGVPTPNIT--WFKDGA 1541
Query: 245 GTSMGKKTQRSLSA-ELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLT 303
K + +L++ + SDAG Y C+A N V K + V +P +
Sbjct: 1542 LLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNA-VGAAEKATRLDVYVPPTIEGAG 1600
Query: 304 LRSPGAQAAVGDLLELHCEALRGSPPILYQFYHE--DVTLGNSSAPSGGGASFNLSLTAE 361
R +A G + L C A RG P ++HE V N S G+ L E
Sbjct: 1601 GRPYVVKAVAGRPVALECVA-RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGE 1659
Query: 362 -HSGNYSCEANNGLG 375
SG YSC A++ G
Sbjct: 1660 ASSGLYSCVASSPAG 1674
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/239 (24%), Positives = 96/239 (40%), Gaps = 23/239 (9%)
Query: 157 SSSPELQISAVWSEDTGSYWCKA--ETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGG 214
S + +I + G+Y C A T R + Q + + Q +P NV+
Sbjct: 476 SGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVT-------- 527
Query: 215 QVTEGQKLILLCSVAGGTGNVTFSWYRE--ATGTSMGKKTQRSLSAELEIPAVKESDAGK 272
V+ G+ +L C V G +W R+ S G+ Q + LEI + +D G+
Sbjct: 528 -VSPGETAVLSCRVLG-EAPYNLTWVRDWRVLPASTGRVAQLA-DLSLEISGIIPTDGGR 584
Query: 273 YYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILY 332
Y C A N + ++ V + VR P +++ + + G +++ C A G P
Sbjct: 585 YQCVASNANGVTRASVW-LLVR---EAPQVSIHTSSQHFSQGVEVKVSCSA-SGYPTPHI 639
Query: 333 QFYHEDVTLGNSSA--PSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGP 389
+ E L S G + E +GNYSC+A N +G E V + + P
Sbjct: 640 SWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTD-QETVTLYYTDP 697
Score = 46.6 bits (109), Expect = 5e-05
Identities = 71/255 (27%), Positives = 97/255 (38%), Gaps = 41/255 (16%)
Query: 156 WSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQ 215
+S P LQI V D G Y C A + +S+ V + ++E
Sbjct: 1844 YSLPPPLQIEKVDLRDEGIYTCAATNLAG-------ESKREVALKVLVPPNIEPGPVNKA 1896
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAE-LEIPAVKESDAGKYY 274
V E + L C +A G SW++ S S+ L I + SDAG Y
Sbjct: 1897 VLENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 1955
Query: 275 CRADN--GHVPIQSKV-VNIPVRI--PVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPP 329
C A N G ++ + VN+P RI P S P V + L C A P
Sbjct: 1956 CVASNVAGSTELRYGLRVNVPPRITLPPSLP--------GPVLVNTPVRLTCNATGAPSP 2007
Query: 330 ILYQFYHEDVTLGNSSAPSG--------GGASFNL-SLTAEHSGNYSCEANNGLGAQCSE 380
L + +D GN +P+G GG L S A SG YSC A + +G +
Sbjct: 2008 TL--MWLKD---GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD 2062
Query: 381 AV-----PVSISGPD 390
V P SI G +
Sbjct: 2063 VVLQVHMPPSILGEE 2077
Score = 45.4 bits (106), Expect = 1e-04
Identities = 79/286 (27%), Positives = 113/286 (39%), Gaps = 46/286 (16%)
Query: 129 ETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAE----TVTH 184
E RLS RL L + E +L SG L+++ V D+G Y C A + +H
Sbjct: 1058 EMRLSVNRL--ALSKYVWEEYGLLPSG-----SLRLAQVQVGDSGHYECTASNPAGSASH 1110
Query: 185 RIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREAT 244
R L Q+ Q P V +V G+ L L C VA G SW ++
Sbjct: 1111 RY---VLGVQVPPQVQPGPRVL--------KVLVGEALDLNC-VAEGNPEPQLSWSKDGV 1158
Query: 245 GTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTL 304
G+ Q S+ A++ SDAG+Y C A N + + V + V P
Sbjct: 1159 -VLQGRGPQGSV----HFAAIRTSDAGRYRCEASNS-AGVDAWEVELRVLEPPHWGA-DE 1211
Query: 305 RSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGG---------GASFN 355
S + G+ L C A RG+P + G SS P G G+ F
Sbjct: 1212 TSGLLERVAGENASLPCPA-RGTPKPQVTWRK-----GPSSEPLHGQPGVAVLEEGSLFL 1265
Query: 356 LSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGV 401
S++ SG+Y C+A N +G+ S + + P R D A V
Sbjct: 1266 ASVSPADSGDYECQATNEVGS-TSRRAKLVVYVPPSIREDGRKANV 1310
Score = 42.7 bits (99), Expect = 8e-04
Identities = 60/242 (24%), Positives = 98/242 (40%), Gaps = 38/242 (15%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQV----- 216
LQI ED G Y C VT+ + + + V P S+ P G+V
Sbjct: 2597 LQILNAQKEDAGQYTC---VVTNELGEAVKNYHVEVLIPP----SISKDDPLGEVGVKEV 2649
Query: 217 -TEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAEL-EIPAVKESDAGKYY 274
T+ + L + T WY++ + + Q L +I + SD+G+Y
Sbjct: 2650 KTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYL 2709
Query: 275 CRADNGHVPIQSKVVNIPVRIP----------VSRPVLTLRSPGAQAAVGDLLE------ 318
C A N + N+ +++P + +L+ R A+ V + E
Sbjct: 2710 CVATNV-AGEDDQDFNVLIQVPPMFQKVGDFSAAFEILS-REEEARGGVTEYREIVENNP 2767
Query: 319 --LHCEALRGSPPILYQFYHEDVTL--GNSSAPSGGGASFNLSLT-AEHSGNYSCEANNG 373
L+C+ PP L +Y ED L G+ + GG + L AE++G YSC+A+N
Sbjct: 2768 AYLYCDTNAIPPPDL-TWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNE 2826
Query: 374 LG 375
+G
Sbjct: 2827 VG 2828
Score = 42.7 bits (99), Expect = 8e-04
Identities = 79/326 (24%), Positives = 120/326 (36%), Gaps = 48/326 (14%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRP---VLTASSFQPIEGGPVS 125
IQ + D+G+Y C + ++ ++ + P LTA + P
Sbjct: 3730 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHT-------PAL 3782
Query: 126 LKCETRLSP----------QRLDVQLQFCFFR---ENQVLGSGWSSSPELQISAVWSEDT 172
L CE SP Q+LD +LQ +R N +L + Q V S +
Sbjct: 3783 LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEV 3842
Query: 173 GSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGT 232
G HR+ Q +HV I++ + VT ++L C + G
Sbjct: 3843 GE--------AHRL----YQVTVHVPPT-IADDQTDFT-----VTMMAPVVLTCH-STGI 3883
Query: 233 GNVTFSWYREATGT-SMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNI 291
T SW + + G + S S LEI AG+Y C A N V
Sbjct: 3884 PAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLT 3943
Query: 292 PVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALR-GSPPILYQFYHEDVTLGNSSAPSGG 350
PV +P+ ++ +A + + L CEA P I +Q +V G S+ G
Sbjct: 3944 VQASPVVKPLPSV----VRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG 3999
Query: 351 GASFNLSLTAEHSGNYSCEANNGLGA 376
G + E +GNY C A N G+
Sbjct: 4000 GQLRIAHASPEDAGNYLCIAKNSAGS 4025
Score = 40.4 bits (93), Expect = 0.004
Identities = 75/326 (23%), Positives = 117/326 (35%), Gaps = 49/326 (15%)
Query: 72 AVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQEL---FQRPVLTASSFQP------IEGG 122
A L+ G Y C + SN+V Q+L P A +P ++ G
Sbjct: 2225 AQLAQEGTYTC----------ECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDG 2274
Query: 123 PVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGW-----SSSPELQISAVWSEDTGSYWC 177
+L+C P + R+ Q +G+ + L + + TG Y C
Sbjct: 2275 VATLECNATGKPPPT-----VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSC 2329
Query: 178 KAETVTHRI-RKQSLQSQIHVQRI----PISNVSLEIRAPGGQVTEGQKLILLCSVAGGT 232
AE + R RK L + + I P++N++ + +P L LLC A G
Sbjct: 2330 VAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSP---------LTLLCE-AMGI 2379
Query: 233 GNVTFSWYREATGTSMGKKTQRSLSA-ELEIPAVKESDAGKYYCRADNGHVPIQSKVVNI 291
W+R S G+ T L++ +E D+G Y C A N + ++
Sbjct: 2380 PPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASN-EAGEARRNFSV 2438
Query: 292 PVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYH-EDVTLGNSSAPSGG 350
V +P S L + G L C P L F + G++ S
Sbjct: 2439 EVLVPPSIENEDLEEV-IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD 2497
Query: 351 GASFN-LSLTAEHSGNYSCEANNGLG 375
G L +G+YSC A N +G
Sbjct: 2498 GVLLQVLQANLSSAGHYSCIAANAVG 2523
Score = 39.7 bits (91), Expect = 0.007
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 43/250 (17%)
Query: 152 LGSGWSS------SPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNV 205
LG+G S S L +V ED Y C+A V +++ ++ I P
Sbjct: 831 LGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEA--RLIVTGHAPPQIA 888
Query: 206 SLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAV 265
S AP +V EGQ + L C V G W ++ G + L +
Sbjct: 889 S---SAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRA 945
Query: 266 KESDAGKYYCRADN----GHVPIQSKVVNIPVRIPVSRPVLT--LRSPGAQAAVGDLLEL 319
+ AG+Y C A N H ++ VV +P RI P T + + G A+ L
Sbjct: 946 LQEHAGRYSCVATNTAGSQHRDVE-LVVQVPPRI---HPTATHHITNEGVPAS------L 995
Query: 320 HCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSL---------TAEHSGNYSCEA 370
C A G P + E ++A + G +N+S +A+ +G Y C A
Sbjct: 996 PCVA-SGVPAPTITWTKE------TNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTA 1048
Query: 371 NNGLGAQCSE 380
N +G E
Sbjct: 1049 TNTVGFSSQE 1058
Score = 38.9 bits (89), Expect = 0.011
Identities = 42/145 (28%), Positives = 56/145 (38%), Gaps = 21/145 (14%)
Query: 150 QVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHV----QRIPISNV 205
QVLG G LQI D+G Y C A V Q I V Q++ +
Sbjct: 2687 QVLGEGRL----LQIQPTQVSDSGRYLCVATNVAGE-DDQDFNVLIQVPPMFQKVGDFSA 2741
Query: 206 SLEI-----RAPGG-----QVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRS 255
+ EI A GG ++ E L C +WYRE S G +
Sbjct: 2742 AFEILSREEEARGGVTEYREIVENNPAYLYCDT-NAIPPPDLTWYREDQPLSAGDEVSVL 2800
Query: 256 LSAE-LEIPAVKESDAGKYYCRADN 279
L+IP V+ +AG+Y C+A N
Sbjct: 2801 QGGRVLQIPLVRAENAGRYSCKASN 2825
Score = 38.5 bits (88), Expect = 0.015
Identities = 83/349 (23%), Positives = 123/349 (35%), Gaps = 80/349 (22%)
Query: 112 TASSFQPIEGGPVSLKC---ETRLSPQRLDVQLQFCFFRENQVLGSGWSSS----PELQI 164
+A + + +EG PVSL C R P+R + ++ + L G S L +
Sbjct: 890 SAPTVRVLEGQPVSLPCIVLAGRPLPER-------HWLKDGRPLPPGSRHSIRADGSLHL 942
Query: 165 SAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLIL 224
E G Y C A T+ Q ++ VQ P + A EG L
Sbjct: 943 DRALQEHAGRYSCVA---TNTAGSQHRDVELVVQVPP----RIHPTATHHITNEGVPASL 995
Query: 225 LCSVAGGTGNVTFSWYREATG-TSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVP 283
C VA G T +W +E TS G S L I DAG Y C A N V
Sbjct: 996 PC-VASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATN-TVG 1053
Query: 284 IQSKVVNIPV-RIPVSRPV--------------------------LTLRSPGAQAA---- 312
S+ + + V R+ +S+ V T +P A+
Sbjct: 1054 FSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYV 1113
Query: 313 -------------------VGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGAS 353
VG+ L+L+C A G+P + + V L G+
Sbjct: 1114 LGVQVPPQVQPGPRVLKVLVGEALDLNCVA-EGNPEPQLSWSKDGVVLQGRGPQ---GSV 1169
Query: 354 FNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVL 402
++ +G Y CEA+N G E V + + P + D T+G+L
Sbjct: 1170 HFAAIRTSDAGRYRCEASNSAGVDAWE-VELRVLEPPHWGAD-ETSGLL 1216
Score = 36.6 bits (83), Expect = 0.055
Identities = 70/309 (22%), Positives = 116/309 (37%), Gaps = 41/309 (13%)
Query: 28 VFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSDSGNYFC--STK 85
V G+++ L C E N + Q +++ KD L + SD+G Y C S
Sbjct: 1131 VLVGEALDLNCVAEGNPEPQ-LSWSKDGVVLQGRGPQGSVHFAAIRTSDAGRYRCEASNS 1189
Query: 86 GQLFLWDKTSNIVKIKVQELFQRPV-LTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFC 144
+ W+ V+++V E T+ + + G SL C R +P+ Q+ +
Sbjct: 1190 AGVDAWE-----VELRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKP---QVTWR 1241
Query: 145 FFRENQVL----GSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRI 200
++ L G L +++V D+G Y C+A T+ + S ++++ V
Sbjct: 1242 KGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQA---TNEVGSTSRRAKLVVYVP 1298
Query: 201 PISNVSLEIRAPGGQVTEGQKLILLCSVAG------------GTGNVTFSWYREATGTSM 248
P ++ + R GQ L L C G V W
Sbjct: 1299 P--SIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGW 1356
Query: 249 GKKTQRSLSAE---LEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLR 305
G+ L E L P ++E D+G Y CRA+N Q+ + V P L
Sbjct: 1357 GQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAEN-----QAGTAQRDFHLLVLTPPSVLG 1411
Query: 306 SPGAQAAVG 314
+ AQ +G
Sbjct: 1412 AGAAQEVLG 1420
Score = 36.6 bits (83), Expect = 0.055
Identities = 84/348 (24%), Positives = 130/348 (37%), Gaps = 56/348 (16%)
Query: 69 IQSAVLSDSGNYFCSTKG-----QLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGP 123
I+ A LSD+G+Y C +L + + +I + PVL + P
Sbjct: 1943 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNT--------P 1994
Query: 124 VSLKCETRLSPQRLDVQLQFCFFRENQVLGSG------WSSSPELQISAVWSEDTGSYWC 177
V L C +P + L+ N V +G + L +++ + D+G Y C
Sbjct: 1995 VRLTCNATGAPSPTLMWLK----DGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC 2050
Query: 178 KAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTF 237
A + R Q + Q+H +P S + E+ V + + L C +
Sbjct: 2051 VAVSAVGEDR-QDVVLQVH---MPPSILGEELNV---SVVANESVALECQ-SHAMPPPVL 2102
Query: 238 SWYREATGTSMGKKTQRSLSAE---LEIPAVKESDAGKYYCRADN--GHVPIQSKVVNIP 292
SW+++ G + + LSA+ L++ DAG Y C A N GH K N+
Sbjct: 2103 SWWKD--GRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGH---SEKHYNLN 2157
Query: 293 VRIPVSRPVLTLR-SPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTL-----GNSSA 346
V + PV LR S G L CE RG P + + L G
Sbjct: 2158 VWV---APVFPLRESHTLTVREGHPTSLSCEC-RGVPFPKISWRKDGQPLPGEGAGLQHV 2213
Query: 347 PSGGGASFNLSLTAEHSGNYSCEANNGLG-----AQCSEAVPVSISGP 389
+ G + G Y+CE +N +G Q VP I+GP
Sbjct: 2214 SAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGP 2261
Score = 33.9 bits (76), Expect = 0.36
Identities = 30/119 (25%), Positives = 45/119 (37%), Gaps = 9/119 (7%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQK 221
LQ+ A+ + D+G Y C A S+ ++ + +P ++ P V+ Q
Sbjct: 3637 LQLQALSTADSGDYSCTARNAAG---STSVAFRVEIHTVP----TIRSGPPAVNVSVNQT 3689
Query: 222 LILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSL-SAELEIPAVKESDAGKYYCRADN 279
+L C A G SW ++ L L I V DAG Y C A N
Sbjct: 3690 ALLPCQ-ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN 3747
Score = 32.7 bits (73), Expect = 0.80
Identities = 79/351 (22%), Positives = 123/351 (35%), Gaps = 73/351 (20%)
Query: 58 LSVFKKFSDFLIQSAVLSDSGNYFC---STKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
L VF + SA SDSG Y C S G+ D+ ++++ + L S
Sbjct: 2026 LQVFPGGRVLTLASARASDSGRYSCVAVSAVGE----DRQDVVLQVHMPPSILGEELNVS 2081
Query: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISA-------- 166
+ V+L+C++ P + ++++ + L P + +SA
Sbjct: 2082 V---VANESVALECQSHAMPPPV-----LSWWKDGRPL----EPRPGVHLSADKALLQVD 2129
Query: 167 ---VWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQ-RIPISNVSLEIRAPGGQVTEGQKL 222
VW D G Y C+A Q+ S+ H + ++ V + V EG
Sbjct: 2130 RADVW--DAGHYTCEA-------LNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPT 2180
Query: 223 ILLCSVAGGTGNVTF---SWYREAT---GTSMGKKTQRSLSAELEIPAVKESDAGKYYCR 276
L C G V F SW ++ G G + ++ L + + + G Y C
Sbjct: 2181 SLSCECRG----VPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCE 2236
Query: 277 ADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAV--GDLLELHCEALRGSPPILYQF 334
N V S+ + + V +P + R P Q +V + L C A PP
Sbjct: 2237 CSNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATLECNATGKPPPT---- 2289
Query: 335 YHEDVTLGNSSAPSGGGASFNLS----------LTAEHSGNYSCEANNGLG 375
VT P G L A H+G YSC A N G
Sbjct: 2290 ----VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAG 2336
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 69.3 bits (168), Expect = 8e-12
Identities = 88/360 (24%), Positives = 150/360 (41%), Gaps = 30/360 (8%)
Query: 31 GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFL------IQSAVLSDSGNYFCST 84
GD VL C+ + + + ++KD + L + ++ IQ A +SD G Y C
Sbjct: 1765 GDKAVLSCETDALPE-PTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKV 1823
Query: 85 KGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFC 144
+T + ++V F+ P + + G P+ L C+ P L+
Sbjct: 1824 SNVAGEAVRTFTLT-VQVPPTFENP--KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDR 1880
Query: 145 FFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISN 204
E+ + S LQ+S + G+Y C AE RK + + + RI S
Sbjct: 1881 MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSG 1940
Query: 205 VSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREAT--GTSMGKKTQRSL-SAELE 261
V+ E V EGQ++ L C A G +W ++ + G MG + L L
Sbjct: 1941 VARE-----HHVLEGQEVRLDCE-ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLV 1994
Query: 262 IPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAV---GDLLE 318
+ ++ SDAG Y C A N +++ + V +P P + + G+ V G+L+
Sbjct: 1995 LKGLRASDAGAYTCVAHN-PAGEDARLHTVNVLVP---PTIKQGADGSGTLVSRPGELVT 2050
Query: 319 LHCEALRGSPPILYQFYHEDVTLGNSSAP--SGGGASFNLS-LTAEHSGNYSCEANNGLG 375
+ C +RGSPPI + + + L S G G + +S + +G ++C A + G
Sbjct: 2051 MVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAG 2109
Score = 62.0 bits (149), Expect = 1e-09
Identities = 76/334 (22%), Positives = 132/334 (39%), Gaps = 38/334 (11%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKC 128
I L+D+G + C + D+ + +++V + + PV + + G V L C
Sbjct: 2089 ISKVQLADAGIFTCVAASPAGVADRNFTL-QVQVPPVLE-PVEFQNDVVVVRGSLVELPC 2146
Query: 129 ETRLSPQRLDVQLQFCFFRENQ-VLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIR 187
E R P L + ++ + +L P LQ+ AV + D+G+Y C A + R
Sbjct: 2147 EARGVPLPL-----VSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 2201
Query: 188 KQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTS 247
+ + + I S E+ +T G + LLC A GT +W+++ +
Sbjct: 2202 RHFQLTVMEPPHIEDSGQPTEL-----SLTPGAPMELLCD-AQGTPQPNITWHKDGQALT 2255
Query: 248 MGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSP 307
+ R+ ++ DAG Y C A++ I+ R+ V P +
Sbjct: 2256 RLENNSRATR------VLRVRDAGLYTCLAESPAGAIEKS-----FRVRVQAPPNIVGPR 2304
Query: 308 GAQAAVG---DLLELHCEALRGSPPILYQFYHEDVTL---GNSSAPSGGGASFNLSLTAE 361
G + VG L L C ++ P ++ + + L ++ P G +L+
Sbjct: 2305 GPRFVVGLAPGQLVLEC-SVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTA 2363
Query: 362 HSGNYSCEANNGLGAQC------SEAVPVSISGP 389
SG+YSC A N G+ VP SGP
Sbjct: 2364 DSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGP 2397
Score = 60.8 bits (146), Expect = 3e-09
Identities = 82/351 (23%), Positives = 137/351 (39%), Gaps = 39/351 (11%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSF------------ 116
IQ +SDSG Y C D+ N++ I+V +FQ+ +++F
Sbjct: 1415 IQPTQVSDSGRYLCVATNVAGEDDQDFNVL-IQVPPMFQKVGDFSAAFEILSREEEARGG 1473
Query: 117 -----QPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSG-----WSSSPELQISA 166
+ +E P L C+T P ++RE+Q L +G LQI
Sbjct: 1474 VTEYREIVENNPAYLYCDTNAIPPP-----DLTWYREDQPLSAGDEVSVLQGGRVLQIPL 1528
Query: 167 VWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLC 226
V +E+ G Y CKA ++ + + L ++ V P+ E V + L C
Sbjct: 1529 VRAENAGRYSCKA---SNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQC 1585
Query: 227 SVAGGTGNVTFSWYREATGTSMGKKTQRSLSAE-LEIPAVKESDAGKYYCRADNGHVPIQ 285
A G T SW + S + Q + L++ + +DA Y C A+N
Sbjct: 1586 P-ALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAEN-QAGSA 1643
Query: 286 SKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEA-LRGSPPILYQFYHEDVTLGNS 344
K+ + V++P L L A + + L C+ +P + + + ++LG
Sbjct: 1644 EKLFTLRVQVPPRIAGLDLEQ--VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEE 1701
Query: 345 SAPSGGGASFNLS-LTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRR 394
G + L SG Y+CEA N G + V +S+ P +R+
Sbjct: 1702 VFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRD-QKLVQLSVLVPPAFRQ 1751
Score = 58.5 bits (140), Expect = 1e-08
Identities = 68/229 (29%), Positives = 99/229 (43%), Gaps = 22/229 (9%)
Query: 150 QVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEI 209
QVL G +L+I+ ED G+Y C A+ ++ ++ VQ P+ +E
Sbjct: 2713 QVLPGG-----QLRIAHASPEDAGNYLCIAKNSAGSAMGKT---RLVVQVPPV----IEN 2760
Query: 210 RAPGGQVTEGQKLILLCSVAGGTG-NVTFSWYREATGTSMGKKTQRSLSAELEIPAVKES 268
P TEG L C G N+T+ + + GK T + S EL + ++
Sbjct: 2761 GLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQP-SGELLVKNLEGQ 2819
Query: 269 DAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSP 328
DAG Y C A+N V + V++ + + PV T +GD L L C A RGSP
Sbjct: 2820 DAGTYTCTAENA-VGRARRRVHLTILV---LPVFTTLPGDRSLRLGDRLWLRCAA-RGSP 2874
Query: 329 P--ILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLG 375
I + VT G S GG +++ E SG Y C A N +G
Sbjct: 2875 TPRIGWTVNDRPVTEGVSEQ-DGGSTLQRAAVSREDSGTYVCWAENRVG 2922
Score = 57.4 bits (137), Expect = 3e-08
Identities = 63/238 (26%), Positives = 92/238 (38%), Gaps = 38/238 (15%)
Query: 153 GSGWSSSPE--LQISAVWSEDTGSYWCKAET---VTHRIRKQSLQSQIHVQRIPISNVSL 207
GSG+ SP L+I G Y C A V H+ ++Q+ V+ +P
Sbjct: 2619 GSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSV---- 2674
Query: 208 EIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKE 267
+RA ++ +LL A G T +W +E + G TQ +L I
Sbjct: 2675 -VRAVA------EEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASP 2727
Query: 268 SDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGS 327
DAG Y C A N K + V++P PV+ P G L C+A RGS
Sbjct: 2728 EDAGNYLCIAKNSAGSAMGK-TRLVVQVP---PVIENGLPDLSTTEGSHAFLPCKA-RGS 2782
Query: 328 PPILYQFYHEDVTLGNSSAP-SGGGASFNL---------SLTAEHSGNYSCEANNGLG 375
P ++T P SG F + +L + +G Y+C A N +G
Sbjct: 2783 P-------EPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG 2833
Score = 56.2 bits (134), Expect = 7e-08
Identities = 86/378 (22%), Positives = 146/378 (38%), Gaps = 37/378 (9%)
Query: 27 SVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELS------VFKKFSDFLIQSAVLSDSGNY 80
S EG L C+ + + + + KD + +S + + L+++ D+G Y
Sbjct: 2766 STTEGSHAFLPCKARGSPE-PNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTY 2824
Query: 81 FCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTA--SSFQPIEGGPVSLKCETRLSPQ-RL 137
C+ + + + V + + L PV T G + L+C R SP R+
Sbjct: 2825 TCTAENAV---GRARRRVHLTILVL---PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRI 2878
Query: 138 DVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHV 197
+ E G S+ LQ +AV ED+G+Y C AE +R+ + S +HV
Sbjct: 2879 GWTVNDRPVTEGVSEQDGGST---LQRAAVSREDSGTYVCWAE---NRVGRTQAVSFVHV 2932
Query: 198 QRIPI---SNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQR 254
+ P+ S + GG I L V G W ++ +
Sbjct: 2933 KEAPVLQGEAFSYLVEPVGGS-------IQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQ 2985
Query: 255 SLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVG 314
+ L I + DAG+Y C A+N + + KVV + + S PV + G
Sbjct: 2986 LQNGSLTIRRTERDDAGRYQCLAEN-EMGVAKKVV---ILVLQSAPVFQVEPQDMTVRSG 3041
Query: 315 DLLELHCEAL-RGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNG 373
D + L C+A +P I + + + G+ + ++ +G Y C A+N
Sbjct: 3042 DDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNL 3101
Query: 374 LGAQCSEAVPVSISGPDG 391
LG+ + A V P G
Sbjct: 3102 LGSATARAFLVVRGEPQG 3119
Score = 55.1 bits (131), Expect = 2e-07
Identities = 65/240 (27%), Positives = 96/240 (40%), Gaps = 29/240 (12%)
Query: 161 ELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQ----- 215
+LQ+ S D G Y CKA K + R+ + V I GG+
Sbjct: 275 QLQLGRAQSSDAGVYTCKASNAVGAAEKAT--------RLDVY-VPPTIEGAGGRPYVVK 325
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAE---LEIPAVKESDAGK 272
G+ + L C VA G + T SW+ E G + + + L + L + + E+ +G
Sbjct: 326 AVAGRPVALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGL 382
Query: 273 YYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPG-AQAAVGDLLELHCEALRGSPPIL 331
Y C A + P V+ V + V +L G VG LEL C+A GSP
Sbjct: 383 YSCVASS---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQA-SGSPVPT 438
Query: 332 YQFYHED---VTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISG 388
Q+ L S G + +HSG ++C+A N G +E V VS+ G
Sbjct: 439 IQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAE-VEVSVHG 497
Score = 52.4 bits (124), Expect = 1e-06
Identities = 82/315 (26%), Positives = 125/315 (39%), Gaps = 35/315 (11%)
Query: 76 DSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPI---EGGPVSLKCETRL 132
DSG Y C + Q + +++ + VL A + Q + G V L+C T
Sbjct: 98 DSGLYSCRAENQAGTAQRDFHLLVLTPPS-----VLGAGAAQEVLGLAGADVELQCWTSG 152
Query: 133 SPQRLDVQLQFCFFRENQVLGSGWSSSPE----LQISAVWSEDTGSYWCKAETVTHRIRK 188
P Q+++ R+ + G E L+I+ D G Y C A + +
Sbjct: 153 VPTP---QVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQ--- 206
Query: 189 QSLQSQIHVQRIPI---SNVSLEIRAPGGQVTEGQKLILLCSVAG-GTGNVTFSWYREAT 244
Q+ Q+ V P SN + E+ V E + LLC G T N+T W+++
Sbjct: 207 QARDFQLRVHAPPTIWGSNETGEVA-----VMEDHLVQLLCEARGVPTPNIT--WFKDGA 259
Query: 245 GTSMGKKTQRSLSA-ELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLT 303
K + +L++ + SDAG Y C+A N V K + V +P +
Sbjct: 260 LLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNA-VGAAEKATRLDVYVPPTIEGAG 318
Query: 304 LRSPGAQAAVGDLLELHCEALRGSPPILYQFYHE--DVTLGNSSAPSGGGASFNLSLTAE 361
R +A G + L C A RG P ++HE V N S G+ L E
Sbjct: 319 GRPYVVKAVAGRPVALECVA-RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGE 377
Query: 362 -HSGNYSCEANNGLG 375
SG YSC A++ G
Sbjct: 378 ASSGLYSCVASSPAG 392
Score = 46.6 bits (109), Expect = 5e-05
Identities = 71/255 (27%), Positives = 97/255 (38%), Gaps = 41/255 (16%)
Query: 156 WSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQ 215
+S P LQI V D G Y C A + +S+ V + ++E
Sbjct: 562 YSLPPPLQIEKVDLRDEGIYTCAATNLAG-------ESKREVALKVLVPPNIEPGPVNKA 614
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAE-LEIPAVKESDAGKYY 274
V E + L C +A G SW++ S S+ L I + SDAG Y
Sbjct: 615 VLENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 673
Query: 275 CRADN--GHVPIQSKV-VNIPVRI--PVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPP 329
C A N G ++ + VN+P RI P S P V + L C A P
Sbjct: 674 CVASNVAGSTELRYGLRVNVPPRITLPPSLP--------GPVLVNTPVRLTCNATGAPSP 725
Query: 330 ILYQFYHEDVTLGNSSAPSG--------GGASFNL-SLTAEHSGNYSCEANNGLGAQCSE 380
L + +D GN +P+G GG L S A SG YSC A + +G +
Sbjct: 726 TL--MWLKD---GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD 780
Query: 381 AV-----PVSISGPD 390
V P SI G +
Sbjct: 781 VVLQVHMPPSILGEE 795
Score = 42.7 bits (99), Expect = 8e-04
Identities = 79/326 (24%), Positives = 120/326 (36%), Gaps = 48/326 (14%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRP---VLTASSFQPIEGGPVS 125
IQ + D+G+Y C + ++ ++ + P LTA + P
Sbjct: 2448 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHT-------PAL 2500
Query: 126 LKCETRLSP----------QRLDVQLQFCFFR---ENQVLGSGWSSSPELQISAVWSEDT 172
L CE SP Q+LD +LQ +R N +L + Q V S +
Sbjct: 2501 LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEV 2560
Query: 173 GSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGT 232
G HR+ Q +HV I++ + VT ++L C + G
Sbjct: 2561 GE--------AHRL----YQVTVHVPPT-IADDQTDFT-----VTMMAPVVLTCH-STGI 2601
Query: 233 GNVTFSWYREATGT-SMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNI 291
T SW + + G + S S LEI AG+Y C A N V
Sbjct: 2602 PAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLT 2661
Query: 292 PVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALR-GSPPILYQFYHEDVTLGNSSAPSGG 350
PV +P+ ++ +A + + L CEA P I +Q +V G S+ G
Sbjct: 2662 VQASPVVKPLPSV----VRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG 2717
Query: 351 GASFNLSLTAEHSGNYSCEANNGLGA 376
G + E +GNY C A N G+
Sbjct: 2718 GQLRIAHASPEDAGNYLCIAKNSAGS 2743
Score = 41.6 bits (96), Expect = 0.002
Identities = 58/239 (24%), Positives = 95/239 (39%), Gaps = 32/239 (13%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHV---QRIPISNVSLEIRAPGGQVTE 218
LQI ED G Y C VT+ + + + V I + E+ +
Sbjct: 1315 LQILNAQKEDAGQYTC---VVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKV 1371
Query: 219 GQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAEL-EIPAVKESDAGKYYCRA 277
L L C + T WY++ + + Q L +I + SD+G+Y C A
Sbjct: 1372 NSTLTLECE-SWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVA 1430
Query: 278 DNGHVPIQSKVVNIPVRIP----------VSRPVLTLRSPGAQAAVGDLLE--------L 319
N + N+ +++P + +L+ R A+ V + E L
Sbjct: 1431 TNV-AGEDDQDFNVLIQVPPMFQKVGDFSAAFEILS-REEEARGGVTEYREIVENNPAYL 1488
Query: 320 HCEALRGSPPILYQFYHEDVTL--GNSSAPSGGGASFNLSLT-AEHSGNYSCEANNGLG 375
+C+ PP L +Y ED L G+ + GG + L AE++G YSC+A+N +G
Sbjct: 1489 YCDTNAIPPPDL-TWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 1546
Score = 40.4 bits (93), Expect = 0.004
Identities = 75/326 (23%), Positives = 117/326 (35%), Gaps = 49/326 (15%)
Query: 72 AVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQEL---FQRPVLTASSFQP------IEGG 122
A L+ G Y C + SN+V Q+L P A +P ++ G
Sbjct: 943 AQLAQEGTYTC----------ECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDG 992
Query: 123 PVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGW-----SSSPELQISAVWSEDTGSYWC 177
+L+C P + R+ Q +G+ + L + + TG Y C
Sbjct: 993 VATLECNATGKPPPT-----VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSC 1047
Query: 178 KAETVTHRI-RKQSLQSQIHVQRI----PISNVSLEIRAPGGQVTEGQKLILLCSVAGGT 232
AE + R RK L + + I P++N++ + +P L LLC A G
Sbjct: 1048 VAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSP---------LTLLCE-AMGI 1097
Query: 233 GNVTFSWYREATGTSMGKKTQRSLSA-ELEIPAVKESDAGKYYCRADNGHVPIQSKVVNI 291
W+R S G+ T L++ +E D+G Y C A N + ++
Sbjct: 1098 PPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASN-EAGEARRNFSV 1156
Query: 292 PVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYH-EDVTLGNSSAPSGG 350
V +P S L + G L C P L F + G++ S
Sbjct: 1157 EVLVPPSIENEDLEEV-IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD 1215
Query: 351 GASFN-LSLTAEHSGNYSCEANNGLG 375
G L +G+YSC A N +G
Sbjct: 1216 GVLLQVLQANLSSAGHYSCIAANAVG 1241
Score = 38.9 bits (89), Expect = 0.011
Identities = 42/145 (28%), Positives = 56/145 (38%), Gaps = 21/145 (14%)
Query: 150 QVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHV----QRIPISNV 205
QVLG G LQI D+G Y C A V Q I V Q++ +
Sbjct: 1405 QVLGEGRL----LQIQPTQVSDSGRYLCVATNVAGE-DDQDFNVLIQVPPMFQKVGDFSA 1459
Query: 206 SLEI-----RAPGG-----QVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRS 255
+ EI A GG ++ E L C +WYRE S G +
Sbjct: 1460 AFEILSREEEARGGVTEYREIVENNPAYLYCDT-NAIPPPDLTWYREDQPLSAGDEVSVL 1518
Query: 256 LSAE-LEIPAVKESDAGKYYCRADN 279
L+IP V+ +AG+Y C+A N
Sbjct: 1519 QGGRVLQIPLVRAENAGRYSCKASN 1543
Score = 36.6 bits (83), Expect = 0.055
Identities = 84/348 (24%), Positives = 130/348 (37%), Gaps = 56/348 (16%)
Query: 69 IQSAVLSDSGNYFCSTKG-----QLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGP 123
I+ A LSD+G+Y C +L + + +I + PVL + P
Sbjct: 661 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNT--------P 712
Query: 124 VSLKCETRLSPQRLDVQLQFCFFRENQVLGSG------WSSSPELQISAVWSEDTGSYWC 177
V L C +P + L+ N V +G + L +++ + D+G Y C
Sbjct: 713 VRLTCNATGAPSPTLMWLK----DGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC 768
Query: 178 KAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTF 237
A + R Q + Q+H +P S + E+ V + + L C +
Sbjct: 769 VAVSAVGEDR-QDVVLQVH---MPPSILGEELNV---SVVANESVALECQ-SHAMPPPVL 820
Query: 238 SWYREATGTSMGKKTQRSLSAE---LEIPAVKESDAGKYYCRADN--GHVPIQSKVVNIP 292
SW+++ G + + LSA+ L++ DAG Y C A N GH K N+
Sbjct: 821 SWWKD--GRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGH---SEKHYNLN 875
Query: 293 VRIPVSRPVLTLR-SPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTL-----GNSSA 346
V + PV LR S G L CE RG P + + L G
Sbjct: 876 VWV---APVFPLRESHTLTVREGHPTRLSCEC-RGVPFPKISWRKDGQPLPGEGAGLQHV 931
Query: 347 PSGGGASFNLSLTAEHSGNYSCEANNGLG-----AQCSEAVPVSISGP 389
+ G + G Y+CE +N +G Q VP I+GP
Sbjct: 932 SAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGP 979
Score = 33.9 bits (76), Expect = 0.36
Identities = 30/119 (25%), Positives = 45/119 (37%), Gaps = 9/119 (7%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQK 221
LQ+ A+ + D+G Y C A S+ ++ + +P ++ P V+ Q
Sbjct: 2355 LQLQALSTADSGDYSCTARNAAG---STSVAFRVEIHTVP----TIRSGPPAVNVSVNQT 2407
Query: 222 LILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSL-SAELEIPAVKESDAGKYYCRADN 279
+L C A G SW ++ L L I V DAG Y C A N
Sbjct: 2408 ALLPCQ-ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN 2465
Score = 32.3 bits (72), Expect = 1.0
Identities = 79/351 (22%), Positives = 123/351 (35%), Gaps = 73/351 (20%)
Query: 58 LSVFKKFSDFLIQSAVLSDSGNYFC---STKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
L VF + SA SDSG Y C S G+ D+ ++++ + L S
Sbjct: 744 LQVFPGGRVLTLASARASDSGRYSCVAVSAVGE----DRQDVVLQVHMPPSILGEELNVS 799
Query: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISA-------- 166
+ V+L+C++ P + ++++ + L P + +SA
Sbjct: 800 V---VANESVALECQSHAMPPPV-----LSWWKDGRPL----EPRPGVHLSADKALLQVD 847
Query: 167 ---VWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQ-RIPISNVSLEIRAPGGQVTEGQKL 222
VW D G Y C+A Q+ S+ H + ++ V + V EG
Sbjct: 848 RADVW--DAGHYTCEA-------LNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPT 898
Query: 223 ILLCSVAGGTGNVTF---SWYREAT---GTSMGKKTQRSLSAELEIPAVKESDAGKYYCR 276
L C G V F SW ++ G G + ++ L + + + G Y C
Sbjct: 899 RLSCECRG----VPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCE 954
Query: 277 ADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAV--GDLLELHCEALRGSPPILYQF 334
N V S+ + + V +P + R P Q +V + L C A PP
Sbjct: 955 CSNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATLECNATGKPPPT---- 1007
Query: 335 YHEDVTLGNSSAPSGGGASFNLS----------LTAEHSGNYSCEANNGLG 375
VT P G L A H+G YSC A N G
Sbjct: 1008 ----VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAG 1054
>gi|15147240 brother of CDO [Homo sapiens]
Length = 1114
Score = 69.3 bits (168), Expect = 8e-12
Identities = 68/223 (30%), Positives = 97/223 (43%), Gaps = 10/223 (4%)
Query: 159 SPELQISAVWSEDTGSYWCKA-ETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQ-- 215
S LQI ED G Y C A VT ++ ++ V+R + I P Q
Sbjct: 182 SGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARI-IYPPEAQTI 240
Query: 216 -VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYY 274
VT+GQ LIL C VA G +W ++ + + KT R L + L I E D+G Y
Sbjct: 241 IVTKGQSLILEC-VASGIPPPRVTWAKDGSSVTGYNKT-RFLLSNLLIDTTSEEDSGTYR 298
Query: 275 CRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQF 334
C ADNG + V+ V++ P +T+ G +L CE +RG+PP +
Sbjct: 299 CMADNGVGQPGAAVILYNVQV-FEPPEVTMELSQLVIPWGQSAKLTCE-VRGNPPPSVLW 356
Query: 335 YHEDVTLGNSSAPSGGGASFN-LSLTAEHSGNYSCEANNGLGA 376
V L +S + LS+ E G Y C A N +G+
Sbjct: 357 LRNAVPLISSQRLRLSRRALRVLSMGPEDEGVYQCMAENEVGS 399
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 68.6 bits (166), Expect = 1e-11
Identities = 93/388 (23%), Positives = 149/388 (38%), Gaps = 36/388 (9%)
Query: 26 SSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKF--SDFLIQSAVLSDSGNYFCS 83
S V EG+++ L C Q + +HK L + S + +DSG Y C
Sbjct: 2736 SHVAEGETLDLNCVVPGQAHAQ-VTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCR 2794
Query: 84 TKGQ-------LFLWDKTSNIVKIKVQELFQRPVLTA--SSFQPIEGGPVSLKCETRLSP 134
G + + + S + V P + SS + EG + LKC + P
Sbjct: 2795 VMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKC---VVP 2851
Query: 135 QRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQ 194
+ Q+ + R + P L+++ V D+G Y C+ + + L +
Sbjct: 2852 GQAHAQVTW-HKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTI 2910
Query: 195 IHVQRIPISNVSLE----IRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGK 250
PI L I A VTEGQ L L C V G + +WY+
Sbjct: 2911 EPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VVPGQAHAQVTWYKRGGSLPARH 2969
Query: 251 KTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSR--------PVL 302
+T S +L + V +D+G+Y CRA +G P Q + V +P S PV+
Sbjct: 2970 QTHGS---QLRLHLVSPADSGEYVCRAASGPGPEQE--ASFTVTVPPSEGSSYRLRSPVI 3024
Query: 303 TLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLT-AE 361
++ P + G C G+ PI ++ + L ++ S G+ + T
Sbjct: 3025 SIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPS 3084
Query: 362 HSGNYSCEANNGLGAQCSEAVPVSISGP 389
+ G Y C A+N G V +S+ GP
Sbjct: 3085 NHGTYRCVASNAYGV-AQSVVNLSVHGP 3111
Score = 67.8 bits (164), Expect = 2e-11
Identities = 97/398 (24%), Positives = 158/398 (39%), Gaps = 61/398 (15%)
Query: 26 SSVFEGDSIVLKC--QGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQ--SAVLSDSGNYF 81
S V EG ++ L C G+ + ++ +HK L V + L++ A +DSG Y
Sbjct: 2350 SQVAEGQTLDLNCVVPGQSHAQV---TWHKRGGSLPVRHQTHGSLLRLYQASPADSGEYV 2406
Query: 82 CSTKGQLFLWDKTSNIVKIK----VQELFQRPV--LTASSFQPIEGGPVSLKCETRLSPQ 135
C G + S +V I+ V L P + +SS Q EG + L C L
Sbjct: 2407 CRVLGSSVPLE-ASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNC---LVAG 2462
Query: 136 RLDVQLQF-----CFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAE---------- 180
+ Q+ + +QV GS L++ V D+G Y C+
Sbjct: 2463 QAHAQVTWHKRGGSLPARHQVHGS------RLRLLQVTPADSGEYVCRVVGSSGTQEASV 2516
Query: 181 --TVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFS 238
T+ R+ Q + RI S+ SL G L L C VA + T +
Sbjct: 2517 LVTIQQRLSGSHSQGVAYPVRIESSSASL---------ANGHTLDLNCLVASQAPH-TIT 2566
Query: 239 WYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVV-----NIPV 293
WY+ G S+ + Q + + L IP V +D+G+Y C NG ++ ++ +
Sbjct: 2567 WYKR--GGSLPSRHQ-IVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSS 2623
Query: 294 RIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGAS 353
+P P + + S G L+L+C R P + +Y +L + G
Sbjct: 2624 HVPSVSPPIRIESSSPTVVEGQTLDLNCVVAR-QPQAIITWYKRGGSLPSRHQTHGSHLR 2682
Query: 354 FNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDG 391
+ ++ SG Y C ANN + A ++ +S+S G
Sbjct: 2683 LH-QMSVADSGEYVCRANNNIDA-LEASIVISVSPSAG 2718
Score = 66.2 bits (160), Expect = 7e-11
Identities = 77/329 (23%), Positives = 137/329 (41%), Gaps = 21/329 (6%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQ-PIEGGPVS-L 126
I++ LSD+G Y C T +F D+ + + ++ PV++ Q ++ G ++
Sbjct: 1827 IRNVQLSDAGTYVC-TGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEF 1885
Query: 127 KCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRI 186
+C SP L++ Q+ L++ AV D Y C+A + +
Sbjct: 1886 RCSATGSPTPT---LEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQ- 1941
Query: 187 RKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGT 246
Q ++ +HV +++ QV G+ + L C AG + T +W +E
Sbjct: 1942 --QVARAVLHVHGG--GGPRVQVSPERTQVHAGRTVRLYCRAAG-VPSATITWRKEGGSL 1996
Query: 247 SMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKV-VNIPVRIPVSRPVLTLR 305
+++R+ A L IPA+ +DAG Y C A + Q+++ V + S P + +
Sbjct: 1997 PPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIE 2056
Query: 306 SPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGN 365
S G L+L+C + GS +Y +L + G ++ SG
Sbjct: 2057 SSSPSVTEGQTLDLNC-VVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLP-QVSPADSGE 2114
Query: 366 YSCEANNGLGAQCSEAVPVSI-----SGP 389
Y C NG G + ++ VS+ SGP
Sbjct: 2115 YVCRVENGSGPK-EASITVSVLHGTHSGP 2142
Score = 64.3 bits (155), Expect = 2e-10
Identities = 80/341 (23%), Positives = 128/341 (37%), Gaps = 38/341 (11%)
Query: 68 LIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPI-EGGPVSL 126
LI + +D+G Y C +V + + PV SS + EG + L
Sbjct: 2011 LIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDL 2070
Query: 127 KCETRLSPQRLDVQLQFCFFREN-------QVLGSGWSSSPELQISAVWSEDTGSYWCKA 179
C S Q ++R QV GS L++ V D+G Y C+
Sbjct: 2071 NCVVAGS-----AHAQVTWYRRGGSLPPHTQVHGS------RLRLPQVSPADSGEYVCRV 2119
Query: 180 ETVTHRIRKQSLQSQIHVQR-------IPISNVSLEIRAPGGQVTEGQKLILLCSVAGGT 232
E + S +H +P S + I V EGQ L L C V G
Sbjct: 2120 ENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNC-VVPGQ 2178
Query: 233 GNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKV-VNI 291
+ +W++ +T SL L + V +D+G+Y C P+++ V V I
Sbjct: 2179 AHAQVTWHKRGGSLPARHQTHGSL---LRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235
Query: 292 PVR-IPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGG 350
IP P + + S + A G L+L C + G +Y +L + G
Sbjct: 2236 EASVIPGPIPPVRIESSSSTVAEGQTLDLSC-VVAGQAHAQVTWYKRGGSL-PARHQVRG 2293
Query: 351 GASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDG 391
+ + +G Y C A+NG+ A ++ V+++G G
Sbjct: 2294 SRLYIFQASPADAGQYVCRASNGMEA----SITVTVTGTQG 2330
Score = 57.8 bits (138), Expect = 2e-08
Identities = 72/334 (21%), Positives = 124/334 (37%), Gaps = 30/334 (8%)
Query: 75 SDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLT------ASSFQPIEGGPVSLKC 128
+DSG Y C + TS IV I+ P ++ +SS +EG + L C
Sbjct: 2593 ADSGEYVCHVSNGAGSRE-TSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNC 2651
Query: 129 ETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRK 188
PQ + + R + + L++ + D+G Y C+A +
Sbjct: 2652 VVARQPQAIITWYK----RGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEA 2707
Query: 189 Q---SLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATG 245
S+ P S++ + I + V EG+ L L C V G + +W++
Sbjct: 2708 SIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNC-VVPGQAHAQVTWHKRGGS 2766
Query: 246 TSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVV---------NIPVRIP 296
+T+ S L + V +D+G+Y CR P+++ V+ + V P
Sbjct: 2767 LPSHHQTRGS---RLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAP 2823
Query: 297 VSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNL 356
P + + ++ A G L+L C + G ++ L G N
Sbjct: 2824 GGAPPIRIEPSSSRVAEGQTLDLKC-VVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLN- 2881
Query: 357 SLTAEHSGNYSCEANNGLGA-QCSEAVPVSISGP 389
++ SG YSC+ G + S V + S P
Sbjct: 2882 QVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSP 2915
Score = 54.7 bits (130), Expect = 2e-07
Identities = 57/234 (24%), Positives = 95/234 (40%), Gaps = 20/234 (8%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVT--EG 219
LQIS+ D G+Y C A+ +KQ ++ V ++ + +++A ++T G
Sbjct: 3170 LQISSAKPSDAGTYVCLAQNALGTAQKQV---EVIVDTGAMAPGAPQVQAEEAELTVEAG 3226
Query: 220 QKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADN 279
L CS G T W + + + + L IP V + D+G+Y C A +
Sbjct: 3227 HTATLRCSATGSPAP-TIHWSKLRSPLPWQHRLEGDT---LIIPRVAQQDSGQYICNATS 3282
Query: 280 --GHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHE 337
GH + + V P P T A G+ ++L C A G+PP+ +Q+
Sbjct: 3283 PAGHA---EATIILHVESP---PYATTVPEHASVQAGETVQLQCLA-HGTPPLTFQWSRV 3335
Query: 338 DVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDG 391
+L + F + E SG Y C N +G+ + + GP G
Sbjct: 3336 GSSLPGRATARNELLHFERA-APEDSGRYRCRVTNKVGS-AEAFAQLLVQGPPG 3387
Score = 53.1 bits (126), Expect = 6e-07
Identities = 90/380 (23%), Positives = 141/380 (37%), Gaps = 48/380 (12%)
Query: 23 VAPSS--VFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQ--SAVLSDSG 78
+ PSS V EG ++ L C Q + +HK L + L++ +DSG
Sbjct: 2156 IEPSSSHVAEGQTLDLNCVVPGQAHAQ-VTWHKRGGSLPARHQTHGSLLRLHQVTPADSG 2214
Query: 79 NYFC---STKGQLFLWDKTSNIVKIKVQELFQRPV----LTASSFQPIEGGPVSLKCETR 131
Y C T G L + S +V I+ + P+ + +SS EG + L C
Sbjct: 2215 EYVCHVVGTSGPL----EASVLVTIEAS-VIPGPIPPVRIESSSSTVAEGQTLDLSCVVA 2269
Query: 132 LSPQRLDVQLQFCFFRE-------NQVLGSGWSSSPELQISAVWSEDTGSYWCKAET-VT 183
Q +++ +QV GS L I D G Y C+A +
Sbjct: 2270 GQ-----AHAQVTWYKRGGSLPARHQVRGS------RLYIFQASPADAGQYVCRASNGME 2318
Query: 184 HRIRKQSLQSQIHVQRIPISNVS-LEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYRE 242
I +Q P + + I QV EGQ L L C V G + +W++
Sbjct: 2319 ASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC-VVPGQSHAQVTWHKR 2377
Query: 243 ATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKV---VNIPVRIPV-- 297
+ +T SL L + +D+G+Y CR VP+++ V + +P
Sbjct: 2378 GGSLPVRHQTHGSL---LRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALG 2434
Query: 298 SRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLS 357
P + + S +Q A G L+L+C + G ++ +L G L
Sbjct: 2435 VTPTVRIESSSSQVAEGQTLDLNC-LVAGQAHAQVTWHKRGGSLPARHQVHGSRLRL-LQ 2492
Query: 358 LTAEHSGNYSCEANNGLGAQ 377
+T SG Y C G Q
Sbjct: 2493 VTPADSGEYVCRVVGSSGTQ 2512
Score = 48.9 bits (115), Expect = 1e-05
Identities = 69/341 (20%), Positives = 123/341 (36%), Gaps = 37/341 (10%)
Query: 74 LSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPV---------LTASSFQPIEGGPV 124
++DSG Y C + D + I V P + +SS EG +
Sbjct: 2688 VADSGEYVCRANNNI---DALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETL 2744
Query: 125 SLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTH 184
L C + P + Q+ + R + + L++ V D+G Y C+ +
Sbjct: 2745 DLNC---VVPGQAHAQVTW-HKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSG 2800
Query: 185 RIRKQSL-------QSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTF 237
+ L S +HV P + I +V EGQ L L C V G +
Sbjct: 2801 PLEASVLVTIEASGSSAVHVPA-PGGAPPIRIEPSSSRVAEGQTLDLKC-VVPGQAHAQV 2858
Query: 238 SWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNI------ 291
+W++ + L L + V +D+G+Y C+ +++ V+
Sbjct: 2859 TWHKRGGNLPARHQVHGPL---LRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSP 2915
Query: 292 -PVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGG 350
P+ P + + + + G L+L+C + G +Y +L G
Sbjct: 2916 GPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VVPGQAHAQVTWYKRGGSLPARHQTHGS 2974
Query: 351 GASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDG 391
+L A+ SG Y C A +G G + + V++ +G
Sbjct: 2975 QLRLHLVSPAD-SGEYVCRAASGPGPEQEASFTVTVPPSEG 3014
Score = 44.7 bits (104), Expect = 2e-04
Identities = 87/382 (22%), Positives = 145/382 (37%), Gaps = 51/382 (13%)
Query: 25 PSSVFEGDSIVLKC------QGEQNW-KIQKMAYHKDNKELSVFKKFSDFLIQSAVLSDS 77
P V G ++ L+C + W +I + + + + I SA SD+
Sbjct: 3121 PVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDA 3180
Query: 78 GNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQ-PIEGG-PVSLKCETRLSP- 134
G Y C + L K ++ P + A + +E G +L+C SP
Sbjct: 3181 GTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPA 3240
Query: 135 -----QRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQ 189
+L L + ++++ G L I V +D+G Y C A +
Sbjct: 3241 PTIHWSKLRSPLPW----QHRLEGD------TLIIPRVAQQDSGQYICNATSPAGHAEAT 3290
Query: 190 SLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSM- 248
+ +HV+ P + E V G+ + L C +A GT +TF W R G+S+
Sbjct: 3291 II---LHVESPPYATTVPE----HASVQAGETVQLQC-LAHGTPPLTFQWSR--VGSSLP 3340
Query: 249 GKKTQRSLSAELEIPAVKESDAGKYYCRADN--------GHVPIQSKVVNIP-VRIPV-S 298
G+ T R+ E A D+G+Y CR N + +Q ++P IP S
Sbjct: 3341 GRATARNELLHFERAA--PEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGS 3398
Query: 299 RPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSL 358
P + + ++G +E HC A+ +++ E L + G +L
Sbjct: 3399 TPTVQVTPQLETKSIGASVEFHC-AVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQ-NL 3456
Query: 359 TAEHSGNYSCEANNGLG-AQCS 379
G Y C+A+ G AQ S
Sbjct: 3457 DQSCQGTYICQAHGPWGKAQAS 3478
Score = 43.1 bits (100), Expect = 6e-04
Identities = 45/172 (26%), Positives = 65/172 (37%), Gaps = 12/172 (6%)
Query: 207 LEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVK 266
+E+ V +G L C V+G + F W RE QR +EL P+V+
Sbjct: 1679 VEVHPARSIVPQGGSHSLRCQVSGSPPHY-FYWSREDGRPVPSGTQQRHQGSELHFPSVQ 1737
Query: 267 ESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAA-VGDLLELHCEALR 325
SDAG Y C N H S+ + P +T+ +Q+ G + C A
Sbjct: 1738 PSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKS 1797
Query: 326 GSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEH-----SGNYSCEANN 372
SP + L N P+ FN LT + +G Y C +N
Sbjct: 1798 KSPAYTLVW----TRLHNGKLPT-RAMDFNGILTIRNVQLSDAGTYVCTGSN 1844
Score = 34.3 bits (77), Expect = 0.28
Identities = 57/241 (23%), Positives = 90/241 (37%), Gaps = 29/241 (12%)
Query: 142 QFCFFRENQVLGSGWS-SSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRI 200
Q +F+E L G S L+I + G+Y C+A K +Q+ +Q +
Sbjct: 3430 QLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWG---KAQASAQLVIQAL 3486
Query: 201 PISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAEL 260
P +V + IR V G + C +A G +W + G + +
Sbjct: 3487 P--SVLINIRTSVQTVVVGHAVEFEC-LALGDPKPQVTWSKVGGHLRPGIVQSGGV---V 3540
Query: 261 EIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELH 320
I V+ +DAG+Y C A N QS V+ + +P +R P AAV
Sbjct: 3541 RIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAV------- 3593
Query: 321 CEALRGSPPILYQFYHEDVTLG--NSSAPSGGGASFNL----SLTAEHSGNYSCEANNGL 374
P I + D++ + S P N+ S+ + +G Y C A N
Sbjct: 3594 ------FPCIASGYPTPDISWSKLDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQ 3647
Query: 375 G 375
G
Sbjct: 3648 G 3648
Score = 32.3 bits (72), Expect = 1.0
Identities = 60/275 (21%), Positives = 97/275 (35%), Gaps = 31/275 (11%)
Query: 75 SDSGNYFCSTKGQLFLWDKTSNIVKIKVQE----LFQRPVLTAS--SFQPIEGGPVSLKC 128
+DSG Y C + S V + E + PV++ S +G S KC
Sbjct: 2984 ADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKC 3043
Query: 129 ETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPE---LQISAVWSEDTGSYWCKAET---V 182
+ ++ + NQ L SP + I + G+Y C A V
Sbjct: 3044 LIHDGAAPISLEWK----TRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGV 3099
Query: 183 THRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYR- 241
+ S+ V +P V +++ G+ + L C V+ G + W R
Sbjct: 3100 AQSVVNLSVHGPPTVSVLPEGPVWVKV---------GKAVTLEC-VSAGEPRSSARWTRI 3149
Query: 242 EATGTSMGKKTQRSLS--AELEIPAVKESDAGKYYCRADN--GHVPIQSKVVNIPVRIPV 297
+T + ++T + A L+I + K SDAG Y C A N G Q +V+ +
Sbjct: 3150 SSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAP 3209
Query: 298 SRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILY 332
P + G L C A P ++
Sbjct: 3210 GAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIH 3244
>gi|157819143 IgLON family member 5 [Homo sapiens]
Length = 336
Score = 66.2 bits (160), Expect = 7e-11
Identities = 84/324 (25%), Positives = 131/324 (40%), Gaps = 62/324 (19%)
Query: 113 ASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSG---WSSSPELQ------ 163
A ++ EG +L C R+ + + +L +G W+S P ++
Sbjct: 39 ADNYTVCEGDNATLSCFIDEHVTRV------AWLNRSNILYAGNDRWTSDPRVRLLINTP 92
Query: 164 ------ISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIH-VQRIP--ISNVSLEIRAPGG 214
I+ V D G Y C +T R Q +Q++ + +P I N+S +
Sbjct: 93 EEFSILITEVGLGDEGLYTCSFQT-----RHQPYTTQVYLIVHVPARIVNISSPVT---- 143
Query: 215 QVTEGQKLILLCSVAGGTGNVTFSWYREATG-TSMGKKTQRSLSAELEIPAVKESDAGKY 273
V EG + LLC +A G T +W + G TS G+ LEI ++ AG+Y
Sbjct: 144 -VNEGGNVNLLC-LAVGRPEPTVTWRQLRDGFTSEGEI--------LEISDIQRGQAGEY 193
Query: 274 YCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQ 333
C NG + S + V + V+ P A+ A+G L CEA+ PP +Q
Sbjct: 194 ECVTHNG---VNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAM-AVPPADFQ 249
Query: 334 FYHEDVTLGNSSAPS-------GGGASFNLSLTAEHSGNYSCEANNGLGAQCSE------ 380
+Y +D L + +A +++A H GNY+C A N LGA +
Sbjct: 250 WYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRP 309
Query: 381 -AVPVSISGPDGYRRDLMTAGVLW 403
++ S P G L G LW
Sbjct: 310 GSLENSAPRPPGLLALLSALGWLW 333
>gi|156564378 carcinoembryonic antigen-related cell adhesion
molecule 20 5L [Homo sapiens]
Length = 596
Score = 65.9 bits (159), Expect = 9e-11
Identities = 111/464 (23%), Positives = 193/464 (41%), Gaps = 71/464 (15%)
Query: 47 QKMAYHKDNKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIK----- 101
++M KD K L++ ++Q DSG Y C + L + +K
Sbjct: 112 ERMQLSKDGKILTIL------IVQR---EDSGTYQCEARDALLSQRSDPIFLDVKYGPDP 162
Query: 102 VQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPE 161
V+ + V + + +EG ++ ET+ P + +F + +L ++
Sbjct: 163 VEIKLESGVASGEVVEVMEGSSMTFLAETKSHPP-----CAYTWFLLDSILSH---TTRT 214
Query: 162 LQISAVWSEDTGSYWCK-AETVTH-----RIRKQSLQSQIHVQRIPISNVSLEIRAPGGQ 215
I AV E G Y C + + TH ++ + L++ Q +P S+++L
Sbjct: 215 FTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVP-SSLNL-------- 265
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAE---LEIPAVKESDAGK 272
V + + L C + NV W+ +G + LSA+ L I ++ +D G
Sbjct: 266 VENARSVDLTCQTVNQSVNV--QWF--LSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGP 321
Query: 273 YYCRADNGHVPIQSKVVNI-----PVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGS 327
Y C N +S+ + + P ++ ++R + +A + L L C A
Sbjct: 322 YACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWA-ESK 380
Query: 328 PPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGL-GAQCSEAVPVSI 386
P Y++ TL +S+ G +LT EH G Y+C A+N L G S +V V +
Sbjct: 381 PGAEYRW-----TLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
Query: 387 SGPDGYRRDLMTAGVLWGL-FGVLGFTGVALLL-YALFHKISGESS--ATNEP-RGASRP 441
GP + +++G + G+ G+L VA L Y L+ + + S T +P S+P
Sbjct: 436 VGP---QSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQP 492
Query: 442 NPQEFTYSSPT-PDMEELQPVYVNVGSVDVDVVYSQVWSMQQPE 484
P+E PT P E L P Y N+ + + +V MQ P+
Sbjct: 493 IPKE---EHPTEPSSESLSPEYCNISQLQGRI---RVELMQPPD 530
>gi|156564393 carcinoembryonic antigen-related cell adhesion
molecule 20 5S [Homo sapiens]
Length = 584
Score = 65.1 bits (157), Expect = 1e-10
Identities = 107/448 (23%), Positives = 186/448 (41%), Gaps = 68/448 (15%)
Query: 47 QKMAYHKDNKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIK----- 101
++M KD K L++ ++Q DSG Y C + L + +K
Sbjct: 112 ERMQLSKDGKILTIL------IVQR---EDSGTYQCEARDALLSQRSDPIFLDVKYGPDP 162
Query: 102 VQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPE 161
V+ + V + + +EG ++ ET+ P + +F + +L ++
Sbjct: 163 VEIKLESGVASGEVVEVMEGSSMTFLAETKSHPP-----CAYTWFLLDSILSH---TTRT 214
Query: 162 LQISAVWSEDTGSYWCK-AETVTH-----RIRKQSLQSQIHVQRIPISNVSLEIRAPGGQ 215
I AV E G Y C + + TH ++ + L++ Q +P S+++L
Sbjct: 215 FTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVP-SSLNL-------- 265
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAE---LEIPAVKESDAGK 272
V + + L C + NV W+ +G + LSA+ L I ++ +D G
Sbjct: 266 VENARSVDLTCQTVNQSVNV--QWF--LSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGP 321
Query: 273 YYCRADNGHVPIQSKVVNI-----PVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGS 327
Y C N +S+ + + P ++ ++R + +A + L L C A
Sbjct: 322 YACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWA-ESK 380
Query: 328 PPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGL-GAQCSEAVPVSI 386
P Y++ TL +S+ G +LT EH G Y+C A+N L G S +V V +
Sbjct: 381 PGAEYRW-----TLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
Query: 387 SGPDGYRRDLMTAGVLWGL-FGVLGFTGVALLL-YALFHKISGESS--ATNEP-RGASRP 441
GP + +++G + G+ G+L VA L Y L+ + + S T +P S+P
Sbjct: 436 VGP---QSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQP 492
Query: 442 NPQEFTYSSPT-PDMEELQPVYVNVGSV 468
P+E PT P E L P Y N+ +
Sbjct: 493 IPKE---EHPTEPSSESLSPEYCNISQL 517
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 64.7 bits (156), Expect = 2e-10
Identities = 88/361 (24%), Positives = 149/361 (41%), Gaps = 56/361 (15%)
Query: 30 EGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYF 81
EG + VL+C+ K + + K ++ L ++S + I ++D+G Y
Sbjct: 3815 EGATAVLQCELS---KAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYS 3871
Query: 82 CSTKGQLFLWDKTSNIVKIKV-QELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRL--- 137
C GQ ++TS + ++ Q +F+ P+ S Q EG +L+CE +
Sbjct: 3872 CVC-GQ----ERTSATLTVRAPQPVFREPL---QSLQAEEGSTATLQCELSEPTATVVWS 3923
Query: 138 --DVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQI 195
+QLQ RE ++ G + EL + + EDTG Y C + Q+ + +
Sbjct: 3924 KGGLQLQANGRREPRLQGC----TAELVLQDLQREDTGEYTCTCGS-------QATSATL 3972
Query: 196 HVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYR---EATGTSMGKKT 252
V P+ + +V EG L C ++ +V W + + + +
Sbjct: 3973 TVTAAPVRFLR---ELQHQEVDEGGTAHLCCELSRAGASV--EWRKGSLQLFPCAKYQMV 4027
Query: 253 QRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAA 312
Q +AEL + V++ DAG Y C D GH + ++ VR+P RP R +
Sbjct: 4028 QDGAAAELLVRGVEQEDAGDYTC--DTGHT---QSMASLSVRVP--RPKFKTRLQSLEQE 4080
Query: 313 VGDLLELHCEALRGSPPILYQFYHEDVTL--GNSSAPSGGGASFNL---SLTAEHSGNYS 367
GD+ L C+ + Q+ E V L G GA+ L L A+ +G Y+
Sbjct: 4081 TGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYA 4140
Query: 368 C 368
C
Sbjct: 4141 C 4141
Score = 60.1 bits (144), Expect = 5e-09
Identities = 80/363 (22%), Positives = 126/363 (34%), Gaps = 50/363 (13%)
Query: 31 GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYFC 82
G S L C+ Q ++ ++KD K+LS K ++Q A +D+G Y C
Sbjct: 905 GASATLSCEVAQAQT--EVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSC 962
Query: 83 STKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQ 142
GQ + K+ +F + + S Q G +L CE Q +
Sbjct: 963 EAGGQRLSFHLDVKEPKV----VFAKDQVAHSEVQAEAGASATLSCEV------AQAQTE 1012
Query: 143 FCFFRENQVLGSGWSSSPE-------LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQI 195
++++ + L S E L + D G Y C+A R Q + ++
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA-------RGQRVSFRL 1065
Query: 196 HVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKT--- 252
H+ + + Q G +L C VA VT WY++ S K
Sbjct: 1066 HITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVT--WYKDGKKLSSSSKVGME 1123
Query: 253 QRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAA 312
+ + L +P ++DAG+Y C A V + + V QA
Sbjct: 1124 VKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQSV----HNEVQAE 1179
Query: 313 VGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEH-----SGNYS 367
G L CE P +Y + L +SS L + +G YS
Sbjct: 1180 AGTTAMLSCEV--AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYS 1237
Query: 368 CEA 370
CEA
Sbjct: 1238 CEA 1240
Score = 54.3 bits (129), Expect = 3e-07
Identities = 73/346 (21%), Positives = 122/346 (35%), Gaps = 48/346 (13%)
Query: 48 KMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVK 99
++ ++KD K+LS K ++Q A +D+G Y C GQ + + ++ +
Sbjct: 1380 EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQRLSF--SLDVAE 1437
Query: 100 IKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLG------ 153
KV ++PV Q G +L CE Q + ++++ + L
Sbjct: 1438 PKVVFAKEQPV--HREVQAQAGASTTLSCEV------AQAQTEVMWYKDGKKLSFSSKVR 1489
Query: 154 -SGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAP 212
+ L + G Y C+A + Q L +HV + +
Sbjct: 1490 MEAVGCTRRLVVQQAGQAVAGEYSCEAGS-------QRLSFHLHVAEPKAVFAKEQPASR 1542
Query: 213 GGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQR---SLSAELEIPAVKESD 269
Q G L C VA VT WY++ S K + + L + ++D
Sbjct: 1543 EVQAEAGTSATLSCEVAQAQTEVT--WYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQAD 1600
Query: 270 AGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPP 329
AG+Y C+A + + V V +P QA G L CE +
Sbjct: 1601 AGEYSCKAGDQRLSFHLHVAEPKVVFAKEQPA----HREVQAEAGASATLSCEVAQAQTE 1656
Query: 330 ILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEH-----SGNYSCEA 370
+ + Y + L +SS L + +G YSCEA
Sbjct: 1657 VTW--YKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEA 1700
Score = 52.8 bits (125), Expect = 7e-07
Identities = 93/441 (21%), Positives = 156/441 (35%), Gaps = 63/441 (14%)
Query: 31 GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYFC 82
G S L C+ Q ++ ++KD K+LS K ++Q A +D+G+Y C
Sbjct: 997 GASATLSCEVAQAQT--EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSC 1054
Query: 83 STKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQ 142
+GQ + +I + K+ +F + + Q G L CE Q +
Sbjct: 1055 EARGQRVSF--RLHITEPKM--MFAKEQSVHNEVQAEAGASAMLSCEV------AQAQTE 1104
Query: 143 FCFFRENQVLGSGWSSSPE-------LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQI 195
++++ + L S E L + D G Y C+A Q + +
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA-------GGQRVSFHL 1157
Query: 196 HVQR-----IPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGK 250
H+ +V E++A G +L C VA VT WY++ S
Sbjct: 1158 HITEPKGVFAKEQSVHNEVQAEAGTTA-----MLSCEVAQPQTEVT--WYKDGKKLSSSS 1210
Query: 251 KTQ---RSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSP 307
K + + + L + V ++DAG+Y C A V Q + P + ++
Sbjct: 1211 KVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITE-PKAVFAKEQLV---HN 1266
Query: 308 GAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEH----- 362
+ G L CE + + + Y + L +SS A L +
Sbjct: 1267 EVRTEAGASATLSCEVAQAQTEVTW--YKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQAD 1324
Query: 363 SGNYSCEANN---GLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLLY 419
+G Y+CEA SE V +R+ AG + L + + Y
Sbjct: 1325 AGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWY 1384
Query: 420 ALFHKISGESSATNEPRGASR 440
K+S S E G +R
Sbjct: 1385 KDGKKLSSSSKVRMEAVGCTR 1405
Score = 52.0 bits (123), Expect = 1e-06
Identities = 65/321 (20%), Positives = 113/321 (35%), Gaps = 46/321 (14%)
Query: 68 LIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQEL--FQRPVLTASSFQPIEGGPVS 125
L++ D+G Y C ++G + ++ VQ L F + S + GGP
Sbjct: 764 LVRDVARDDAGLYECVSRGGRIAY-------QLSVQGLARFLHKDMAGSCVDAVAGGPAQ 816
Query: 126 LKCETRLSPQRLDVQLQFCFFRENQVLGSGW--------SSSPELQISAVWSEDTGSYWC 177
+CET + + ++++ LG + L + V +D G+Y C
Sbjct: 817 FECETS------EAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870
Query: 178 KAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTF 237
R+ + S+ ++ V + ++ Q G L C VA VT
Sbjct: 871 -------RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVT- 922
Query: 238 SWYREATGTSMGKKT---QRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVR 294
WY++ S K + L + ++DAG+Y C A + V V
Sbjct: 923 -WYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVV 981
Query: 295 IPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASF 354
+ + QA G L CE + +++ Y + L +S
Sbjct: 982 FAKDQ----VAHSEVQAEAGASATLSCEVAQAQTEVMW--YKDGKKLSSSLKVHVEAKGC 1035
Query: 355 NLSLTAEH-----SGNYSCEA 370
L + +G+YSCEA
Sbjct: 1036 RRRLVVQQAGKTDAGDYSCEA 1056
Score = 47.0 bits (110), Expect = 4e-05
Identities = 79/380 (20%), Positives = 149/380 (39%), Gaps = 59/380 (15%)
Query: 31 GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYFC 82
G S L C+ Q ++ ++KD K+LS K ++Q A +D+G Y C
Sbjct: 1549 GTSATLSCEVAQAQT--EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSC 1606
Query: 83 STKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQ 142
Q + ++ + KV +F + Q G +L CE Q +
Sbjct: 1607 KAGDQRLSFHL--HVAEPKV--VFAKEQPAHREVQAEAGASATLSCEVA------QAQTE 1656
Query: 143 FCFFRENQVLGSGWSSSPELQISAVW-----------SEDTGSYWCKAETVTHRIRKQSL 191
++++ + L SSS ++++ AV D G Y C+A Q L
Sbjct: 1657 VTWYKDGKKL----SSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGG-------QRL 1705
Query: 192 QSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKK 251
++HV + R V E + +IL ++A + T +W ++ K+
Sbjct: 1706 SFRLHVAELEPQISERPCRREPLVVKEHEDIILTATLATPSA-ATVTWLKDGVEIRRSKR 1764
Query: 252 TQRSLSAE---LEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIP-VSRPVLTLRSP 307
+ + + L + + D+ Y CR + ++ + PV++ V+ L P
Sbjct: 1765 HETASQGDTHTLTVHGAQVLDSAIYSCR-------VGAEGQDFPVQVEEVAAKFCRLLEP 1817
Query: 308 GAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLS---LTAEHSG 364
+G + L CE ++++ + + +G G +L+ L AE +G
Sbjct: 1818 VC-GELGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAG 1876
Query: 365 NYSCEA-NNGLGAQCSEAVP 383
Y CE+ ++ AQ + +VP
Sbjct: 1877 EYVCESRDDHTSAQLTVSVP 1896
Score = 43.5 bits (101), Expect = 5e-04
Identities = 79/365 (21%), Positives = 137/365 (37%), Gaps = 59/365 (16%)
Query: 26 SSVFEGDSIVLKCQGEQNWKIQKMAYHKDNK--------ELSVFKKFSDFLIQSAVLSDS 77
+++ EG+ + L C E + + + KD K +LS + LI A L DS
Sbjct: 3105 ATITEGEDLTLVC--ETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDS 3162
Query: 78 GNYFCSTKGQLFLWDKTSNIVKIKVQEL-FQRPVLTASSFQPIEGGPVSLKCETRLSPQR 136
G Y C G +S+IV++ + + FQ + + +EGG +L+C
Sbjct: 3163 GRYKCEAGGAC-----SSSIVRVHARPVRFQEAL---KDLEVLEGGAATLRCVL----SS 3210
Query: 137 LDVQLQFCFFRENQVLGSGWSSS-------PELQISAVWSEDTGSYWCKAETVTHRIRKQ 189
+ +++C+ N VL G S EL + + +D+G Y C Q
Sbjct: 3211 VAAPVKWCY--GNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCS-------FGDQ 3261
Query: 190 SLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMG 249
+ + + V +P + + + TEG L C ++ W + + G
Sbjct: 3262 TTSATLTVTALPAQFIG---KLRNKEATEGATATLRCELSKA---APVEWRKGSETLRDG 3315
Query: 250 KK---TQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRS 306
+ Q EL+I + DA +Y C + +P + LR
Sbjct: 3316 DRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHF-----IGRLRH 3370
Query: 307 PGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNL---SLTAEHS 363
++ G L CE L + P+ ++ E + G+ + GA L L +
Sbjct: 3371 --QESIEGATATLRCE-LSKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADA 3427
Query: 364 GNYSC 368
G YSC
Sbjct: 3428 GEYSC 3432
Score = 37.4 bits (85), Expect = 0.032
Identities = 66/309 (21%), Positives = 117/309 (37%), Gaps = 75/309 (24%)
Query: 20 LTLVAP---SSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKF---SDFLIQSAV 73
+TLV P E VL+CQ + ++ + K ++EL K+ SD L + +
Sbjct: 2290 VTLVRPLRDKIAMEKHRGVLECQVSR--ASAQVRWFKGSQELQPGPKYELVSDGLYRKLI 2347
Query: 74 LSD-----SGNYFCS-----TKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGP 123
+SD Y C T Q F+ +++ IV+ +E P
Sbjct: 2348 ISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVR------------GLQDVTVMEPAP 2395
Query: 124 VSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVT 183
+CET + R P+ + + G+ + E
Sbjct: 2396 AWFECETSIPSVR----------------------PPKWLLGKTVLQAGGNVGLEQEGTV 2433
Query: 184 HRIRKQ----SLQSQIHVQ--------RIPISNVSLEIRAPGGQVT--EGQKLILLCSVA 229
HR+ + ++ +H R+ +S++ + + P T E Q ++L C
Sbjct: 2434 HRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFR 2493
Query: 230 GGTGNVTFSWYREATGTSMGKKTQRSLS---AELEIPAVKESDAGKYYCRADNGH----V 282
V WY++ T S +K + SL AEL I + +DAG Y C+A + H V
Sbjct: 2494 PAPKAV--QWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEV 2551
Query: 283 PIQSKVVNI 291
++++ V +
Sbjct: 2552 TVEAREVTV 2560
Score = 35.8 bits (81), Expect = 0.095
Identities = 72/358 (20%), Positives = 126/358 (35%), Gaps = 55/358 (15%)
Query: 30 EGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYF 81
EG + VL+C+ ++ + K ++ L ++S + I+ ++D+G Y
Sbjct: 3551 EGATAVLQCELNSAAPVE---WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYS 3607
Query: 82 CSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCE-TRLSPQRLDVQ 140
C + T + IK E + T EG L+CE ++++P
Sbjct: 3608 CVCGQERTSAMLTVRALPIKFTEGLRNEEAT-------EGATAVLRCELSKMAPVE---- 3656
Query: 141 LQFCFFRENQVLGSGWSSSP-------ELQISAVWSEDTGSYWCKAETVTHRIRKQSLQS 193
+++ ++ L G S ELQI + +ED G Y C K+ +
Sbjct: 3657 ----WWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMC-------GKERTSA 3705
Query: 194 QIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQ 253
+ V+ +P + + TEG L C ++ + Q
Sbjct: 3706 MLTVRAMPSKFIE---GLRNEEATEGDTATLWCELSKAAPVEWRKGHETLRDGDRHSLRQ 3762
Query: 254 RSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAV 313
EL+I + DAG+Y C V +P R +A
Sbjct: 3763 DGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIED-------VKNQEARE 3815
Query: 314 GDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNL---SLTAEHSGNYSC 368
G L CE L + P+ ++ E + G+ + G L L+ +G YSC
Sbjct: 3816 GATAVLQCE-LSKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC 3872
Score = 30.8 bits (68), Expect = 3.0
Identities = 39/182 (21%), Positives = 64/182 (35%), Gaps = 15/182 (8%)
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKE---SDAGK 272
V+ G+ L C + G SW ++ + G + + + +L + + D+G+
Sbjct: 21 VSVGKDATLSCQIVGNP-TPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQ 79
Query: 273 YYCRADNGHVPIQSKV---VNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPP 329
Y CRA N + V V+ P LR + G C + GSP
Sbjct: 80 YVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCR-VGGSPR 138
Query: 330 ILYQFYHEDVTLGNSSAPS------GGGASFNL-SLTAEHSGNYSCEANNGLGAQCSEAV 382
+ + LG P G ++ + + G Y A N LGA + A
Sbjct: 139 PAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAA 198
Query: 383 PV 384
V
Sbjct: 199 LV 200
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 64.7 bits (156), Expect = 2e-10
Identities = 88/361 (24%), Positives = 149/361 (41%), Gaps = 56/361 (15%)
Query: 30 EGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYF 81
EG + VL+C+ K + + K ++ L ++S + I ++D+G Y
Sbjct: 3815 EGATAVLQCELS---KAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYS 3871
Query: 82 CSTKGQLFLWDKTSNIVKIKV-QELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRL--- 137
C GQ ++TS + ++ Q +F+ P+ S Q EG +L+CE +
Sbjct: 3872 CVC-GQ----ERTSATLTVRAPQPVFREPL---QSLQAEEGSTATLQCELSEPTATVVWS 3923
Query: 138 --DVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQI 195
+QLQ RE ++ G + EL + + EDTG Y C + Q+ + +
Sbjct: 3924 KGGLQLQANGRREPRLQGC----TAELVLQDLQREDTGEYTCTCGS-------QATSATL 3972
Query: 196 HVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYR---EATGTSMGKKT 252
V P+ + +V EG L C ++ +V W + + + +
Sbjct: 3973 TVTAAPVRFLR---ELQHQEVDEGGTAHLCCELSRAGASV--EWRKGSLQLFPCAKYQMV 4027
Query: 253 QRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAA 312
Q +AEL + V++ DAG Y C D GH + ++ VR+P RP R +
Sbjct: 4028 QDGAAAELLVRGVEQEDAGDYTC--DTGHT---QSMASLSVRVP--RPKFKTRLQSLEQE 4080
Query: 313 VGDLLELHCEALRGSPPILYQFYHEDVTL--GNSSAPSGGGASFNL---SLTAEHSGNYS 367
GD+ L C+ + Q+ E V L G GA+ L L A+ +G Y+
Sbjct: 4081 TGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYA 4140
Query: 368 C 368
C
Sbjct: 4141 C 4141
Score = 60.1 bits (144), Expect = 5e-09
Identities = 80/363 (22%), Positives = 126/363 (34%), Gaps = 50/363 (13%)
Query: 31 GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYFC 82
G S L C+ Q ++ ++KD K+LS K ++Q A +D+G Y C
Sbjct: 905 GASATLSCEVAQAQT--EVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSC 962
Query: 83 STKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQ 142
GQ + K+ +F + + S Q G +L CE Q +
Sbjct: 963 EAGGQRLSFHLDVKEPKV----VFAKDQVAHSEVQAEAGASATLSCEV------AQAQTE 1012
Query: 143 FCFFRENQVLGSGWSSSPE-------LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQI 195
++++ + L S E L + D G Y C+A R Q + ++
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA-------RGQRVSFRL 1065
Query: 196 HVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKT--- 252
H+ + + Q G +L C VA VT WY++ S K
Sbjct: 1066 HITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVT--WYKDGKKLSSSSKVGME 1123
Query: 253 QRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAA 312
+ + L +P ++DAG+Y C A V + + V QA
Sbjct: 1124 VKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQSV----HNEVQAE 1179
Query: 313 VGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEH-----SGNYS 367
G L CE P +Y + L +SS L + +G YS
Sbjct: 1180 AGTTAMLSCEV--AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYS 1237
Query: 368 CEA 370
CEA
Sbjct: 1238 CEA 1240
Score = 54.3 bits (129), Expect = 3e-07
Identities = 73/346 (21%), Positives = 122/346 (35%), Gaps = 48/346 (13%)
Query: 48 KMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVK 99
++ ++KD K+LS K ++Q A +D+G Y C GQ + + ++ +
Sbjct: 1380 EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQRLSF--SLDVAE 1437
Query: 100 IKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLG------ 153
KV ++PV Q G +L CE Q + ++++ + L
Sbjct: 1438 PKVVFAKEQPV--HREVQAQAGASTTLSCEV------AQAQTEVMWYKDGKKLSFSSKVR 1489
Query: 154 -SGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAP 212
+ L + G Y C+A + Q L +HV + +
Sbjct: 1490 MEAVGCTRRLVVQQAGQAVAGEYSCEAGS-------QRLSFHLHVAEPKAVFAKEQPASR 1542
Query: 213 GGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQR---SLSAELEIPAVKESD 269
Q G L C VA VT WY++ S K + + L + ++D
Sbjct: 1543 EVQAEAGTSATLSCEVAQAQTEVT--WYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQAD 1600
Query: 270 AGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPP 329
AG+Y C+A + + V V +P QA G L CE +
Sbjct: 1601 AGEYSCKAGDQRLSFHLHVAEPKVVFAKEQPA----HREVQAEAGASATLSCEVAQAQTE 1656
Query: 330 ILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEH-----SGNYSCEA 370
+ + Y + L +SS L + +G YSCEA
Sbjct: 1657 VTW--YKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEA 1700
Score = 52.8 bits (125), Expect = 7e-07
Identities = 93/441 (21%), Positives = 156/441 (35%), Gaps = 63/441 (14%)
Query: 31 GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYFC 82
G S L C+ Q ++ ++KD K+LS K ++Q A +D+G+Y C
Sbjct: 997 GASATLSCEVAQAQT--EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSC 1054
Query: 83 STKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQ 142
+GQ + +I + K+ +F + + Q G L CE Q +
Sbjct: 1055 EARGQRVSF--RLHITEPKM--MFAKEQSVHNEVQAEAGASAMLSCEV------AQAQTE 1104
Query: 143 FCFFRENQVLGSGWSSSPE-------LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQI 195
++++ + L S E L + D G Y C+A Q + +
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA-------GGQRVSFHL 1157
Query: 196 HVQR-----IPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGK 250
H+ +V E++A G +L C VA VT WY++ S
Sbjct: 1158 HITEPKGVFAKEQSVHNEVQAEAGTTA-----MLSCEVAQPQTEVT--WYKDGKKLSSSS 1210
Query: 251 KTQ---RSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSP 307
K + + + L + V ++DAG+Y C A V Q + P + ++
Sbjct: 1211 KVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITE-PKAVFAKEQLV---HN 1266
Query: 308 GAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEH----- 362
+ G L CE + + + Y + L +SS A L +
Sbjct: 1267 EVRTEAGASATLSCEVAQAQTEVTW--YKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQAD 1324
Query: 363 SGNYSCEANN---GLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLLY 419
+G Y+CEA SE V +R+ AG + L + + Y
Sbjct: 1325 AGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWY 1384
Query: 420 ALFHKISGESSATNEPRGASR 440
K+S S E G +R
Sbjct: 1385 KDGKKLSSSSKVRMEAVGCTR 1405
Score = 52.0 bits (123), Expect = 1e-06
Identities = 65/321 (20%), Positives = 113/321 (35%), Gaps = 46/321 (14%)
Query: 68 LIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQEL--FQRPVLTASSFQPIEGGPVS 125
L++ D+G Y C ++G + ++ VQ L F + S + GGP
Sbjct: 764 LVRDVARDDAGLYECVSRGGRIAY-------QLSVQGLARFLHKDMAGSCVDAVAGGPAQ 816
Query: 126 LKCETRLSPQRLDVQLQFCFFRENQVLGSGW--------SSSPELQISAVWSEDTGSYWC 177
+CET + + ++++ LG + L + V +D G+Y C
Sbjct: 817 FECETS------EAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870
Query: 178 KAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTF 237
R+ + S+ ++ V + ++ Q G L C VA VT
Sbjct: 871 -------RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVT- 922
Query: 238 SWYREATGTSMGKKT---QRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVR 294
WY++ S K + L + ++DAG+Y C A + V V
Sbjct: 923 -WYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVV 981
Query: 295 IPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASF 354
+ + QA G L CE + +++ Y + L +S
Sbjct: 982 FAKDQ----VAHSEVQAEAGASATLSCEVAQAQTEVMW--YKDGKKLSSSLKVHVEAKGC 1035
Query: 355 NLSLTAEH-----SGNYSCEA 370
L + +G+YSCEA
Sbjct: 1036 RRRLVVQQAGKTDAGDYSCEA 1056
Score = 47.0 bits (110), Expect = 4e-05
Identities = 79/380 (20%), Positives = 149/380 (39%), Gaps = 59/380 (15%)
Query: 31 GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYFC 82
G S L C+ Q ++ ++KD K+LS K ++Q A +D+G Y C
Sbjct: 1549 GTSATLSCEVAQAQT--EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSC 1606
Query: 83 STKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQ 142
Q + ++ + KV +F + Q G +L CE Q +
Sbjct: 1607 KAGDQRLSFHL--HVAEPKV--VFAKEQPAHREVQAEAGASATLSCEVA------QAQTE 1656
Query: 143 FCFFRENQVLGSGWSSSPELQISAVW-----------SEDTGSYWCKAETVTHRIRKQSL 191
++++ + L SSS ++++ AV D G Y C+A Q L
Sbjct: 1657 VTWYKDGKKL----SSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGG-------QRL 1705
Query: 192 QSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKK 251
++HV + R V E + +IL ++A + T +W ++ K+
Sbjct: 1706 SFRLHVAELEPQISERPCRREPLVVKEHEDIILTATLATPSA-ATVTWLKDGVEIRRSKR 1764
Query: 252 TQRSLSAE---LEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIP-VSRPVLTLRSP 307
+ + + L + + D+ Y CR + ++ + PV++ V+ L P
Sbjct: 1765 HETASQGDTHTLTVHGAQVLDSAIYSCR-------VGAEGQDFPVQVEEVAAKFCRLLEP 1817
Query: 308 GAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLS---LTAEHSG 364
+G + L CE ++++ + + +G G +L+ L AE +G
Sbjct: 1818 VC-GELGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAG 1876
Query: 365 NYSCEA-NNGLGAQCSEAVP 383
Y CE+ ++ AQ + +VP
Sbjct: 1877 EYVCESRDDHTSAQLTVSVP 1896
Score = 43.5 bits (101), Expect = 5e-04
Identities = 79/365 (21%), Positives = 137/365 (37%), Gaps = 59/365 (16%)
Query: 26 SSVFEGDSIVLKCQGEQNWKIQKMAYHKDNK--------ELSVFKKFSDFLIQSAVLSDS 77
+++ EG+ + L C E + + + KD K +LS + LI A L DS
Sbjct: 3105 ATITEGEDLTLVC--ETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDS 3162
Query: 78 GNYFCSTKGQLFLWDKTSNIVKIKVQEL-FQRPVLTASSFQPIEGGPVSLKCETRLSPQR 136
G Y C G +S+IV++ + + FQ + + +EGG +L+C
Sbjct: 3163 GRYKCEAGGAC-----SSSIVRVHARPVRFQEAL---KDLEVLEGGAATLRCVL----SS 3210
Query: 137 LDVQLQFCFFRENQVLGSGWSSS-------PELQISAVWSEDTGSYWCKAETVTHRIRKQ 189
+ +++C+ N VL G S EL + + +D+G Y C Q
Sbjct: 3211 VAAPVKWCY--GNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCS-------FGDQ 3261
Query: 190 SLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMG 249
+ + + V +P + + + TEG L C ++ W + + G
Sbjct: 3262 TTSATLTVTALPAQFIG---KLRNKEATEGATATLRCELSKA---APVEWRKGSETLRDG 3315
Query: 250 KK---TQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRS 306
+ Q EL+I + DA +Y C + +P + LR
Sbjct: 3316 DRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHF-----IGRLRH 3370
Query: 307 PGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNL---SLTAEHS 363
++ G L CE L + P+ ++ E + G+ + GA L L +
Sbjct: 3371 --QESIEGATATLRCE-LSKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADA 3427
Query: 364 GNYSC 368
G YSC
Sbjct: 3428 GEYSC 3432
Score = 37.4 bits (85), Expect = 0.032
Identities = 66/309 (21%), Positives = 117/309 (37%), Gaps = 75/309 (24%)
Query: 20 LTLVAP---SSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKF---SDFLIQSAV 73
+TLV P E VL+CQ + ++ + K ++EL K+ SD L + +
Sbjct: 2290 VTLVRPLRDKIAMEKHRGVLECQVSR--ASAQVRWFKGSQELQPGPKYELVSDGLYRKLI 2347
Query: 74 LSD-----SGNYFCS-----TKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGP 123
+SD Y C T Q F+ +++ IV+ +E P
Sbjct: 2348 ISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVR------------GLQDVTVMEPAP 2395
Query: 124 VSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVT 183
+CET + R P+ + + G+ + E
Sbjct: 2396 AWFECETSIPSVR----------------------PPKWLLGKTVLQAGGNVGLEQEGTV 2433
Query: 184 HRIRKQ----SLQSQIHVQ--------RIPISNVSLEIRAPGGQVT--EGQKLILLCSVA 229
HR+ + ++ +H R+ +S++ + + P T E Q ++L C
Sbjct: 2434 HRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFR 2493
Query: 230 GGTGNVTFSWYREATGTSMGKKTQRSLS---AELEIPAVKESDAGKYYCRADNGH----V 282
V WY++ T S +K + SL AEL I + +DAG Y C+A + H V
Sbjct: 2494 PAPKAV--QWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEV 2551
Query: 283 PIQSKVVNI 291
++++ V +
Sbjct: 2552 TVEAREVTV 2560
Score = 35.8 bits (81), Expect = 0.095
Identities = 72/358 (20%), Positives = 126/358 (35%), Gaps = 55/358 (15%)
Query: 30 EGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS--------DFLIQSAVLSDSGNYF 81
EG + VL+C+ ++ + K ++ L ++S + I+ ++D+G Y
Sbjct: 3551 EGATAVLQCELNSAAPVE---WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYS 3607
Query: 82 CSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCE-TRLSPQRLDVQ 140
C + T + IK E + T EG L+CE ++++P
Sbjct: 3608 CVCGQERTSAMLTVRALPIKFTEGLRNEEAT-------EGATAVLRCELSKMAPVE---- 3656
Query: 141 LQFCFFRENQVLGSGWSSSP-------ELQISAVWSEDTGSYWCKAETVTHRIRKQSLQS 193
+++ ++ L G S ELQI + +ED G Y C K+ +
Sbjct: 3657 ----WWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMC-------GKERTSA 3705
Query: 194 QIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQ 253
+ V+ +P + + TEG L C ++ + Q
Sbjct: 3706 MLTVRAMPSKFIE---GLRNEEATEGDTATLWCELSKAAPVEWRKGHETLRDGDRHSLRQ 3762
Query: 254 RSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAV 313
EL+I + DAG+Y C V +P R +A
Sbjct: 3763 DGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIED-------VKNQEARE 3815
Query: 314 GDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNL---SLTAEHSGNYSC 368
G L CE L + P+ ++ E + G+ + G L L+ +G YSC
Sbjct: 3816 GATAVLQCE-LSKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC 3872
Score = 30.8 bits (68), Expect = 3.0
Identities = 39/182 (21%), Positives = 64/182 (35%), Gaps = 15/182 (8%)
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKE---SDAGK 272
V+ G+ L C + G SW ++ + G + + + +L + + D+G+
Sbjct: 21 VSVGKDATLSCQIVGNP-TPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQ 79
Query: 273 YYCRADNGHVPIQSKV---VNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPP 329
Y CRA N + V V+ P LR + G C + GSP
Sbjct: 80 YVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCR-VGGSPR 138
Query: 330 ILYQFYHEDVTLGNSSAPS------GGGASFNL-SLTAEHSGNYSCEANNGLGAQCSEAV 382
+ + LG P G ++ + + G Y A N LGA + A
Sbjct: 139 PAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAA 198
Query: 383 PV 384
V
Sbjct: 199 LV 200
>gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo
sapiens]
Length = 1336
Score = 62.4 bits (150), Expect = 9e-10
Identities = 82/316 (25%), Positives = 123/316 (38%), Gaps = 29/316 (9%)
Query: 67 FLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPI-EGGPVS 125
FLI S + D GNY C +W + S+ V++ V E + +P L A + G V
Sbjct: 834 FLIISVGIGDGGNYSCRYY-DFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVI 892
Query: 126 LKCETRLSPQRL-------DVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCK 178
L+C+ R V LQF V G +S + + V +ED+G+Y C
Sbjct: 893 LRCQGTFQGMRFALLQEGAHVPLQF-----RSVSG----NSADFLLHTVGAEDSGNYSCI 943
Query: 179 AETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFS 238
T R L + + P V GQ + L C G V +
Sbjct: 944 YYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWC--RGPVHGVGYI 1001
Query: 239 WYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRAD---NGHVPIQ-SKVVNIPVR 294
++E TSM S I + + G+Y C + IQ S + + V
Sbjct: 1002 LHKEGEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVT 1061
Query: 295 IPVSRPVLTLRSPGAQAAVGDLLELHCEA-LRGSPPILYQFYHEDVTLGNSSAPSGGGAS 353
+ +P L L PG A G+ + L C+ L S +L + ++ PSG A
Sbjct: 1062 GLLPKPSL-LAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPL--EQQRPSGYRAD 1118
Query: 354 FNL-SLTAEHSGNYSC 368
F + ++ E SG YSC
Sbjct: 1119 FWMPAVRGEDSGIYSC 1134
Score = 58.9 bits (141), Expect = 1e-08
Identities = 82/385 (21%), Positives = 157/385 (40%), Gaps = 41/385 (10%)
Query: 12 AVTEQADSLTLV----------APSSVFEGDSIVLKCQG---EQNWKIQKMAYHKDNKEL 58
AV+E +++L LV + S G + L+C+G + + K + ++L
Sbjct: 667 AVSEPSEALELVGTDILPKPVISASPTIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQL 726
Query: 59 SVFKKFSDFLIQSAVLSDSGNYFC--STKGQLFLWDKTSNIVKIKVQELFQRPVL-TASS 115
+ + F IQ D GNY C T+ + F W + S +++ ++E++ +P T +S
Sbjct: 727 GAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWAS 786
Query: 116 FQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGS---GW----SSSPELQISAVW 168
G V+ C T P + + F +++ + S W +S+ I +V
Sbjct: 787 PVVTPGARVTFNCST---PHQ---HMSFILYKDGSEIASSDRSWASPGASAAHFLIISVG 840
Query: 169 SEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSV 228
D G+Y C+ + + + P + + PG V G+ +IL C
Sbjct: 841 IGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTL---LAQPGPVVFPGKSVILRCQ- 896
Query: 229 AGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKV 288
G + F+ +E + ++ SA+ + V D+G Y C + +
Sbjct: 897 -GTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSY 955
Query: 289 VNIPVRIPVS----RPVLTLRSPGAQAAVGDLLELHCEA-LRGSPPILYQFYHEDVTLGN 343
+++P+ I V+ +P L P + +G + L C + G IL++ E ++
Sbjct: 956 LSMPLMIWVTDTFPKPWL-FAEPSSVVPMGQNVTLWCRGPVHGVGYILHK-EGEATSMQL 1013
Query: 344 SSAPSGGGASFNLSLTAEHSGNYSC 368
+ S GA +++ G YSC
Sbjct: 1014 WGSTSNDGAFPITNISGTSMGRYSC 1038
Score = 53.1 bits (126), Expect = 6e-07
Identities = 91/382 (23%), Positives = 147/382 (38%), Gaps = 49/382 (12%)
Query: 13 VTEQADSLTLVAPSS--VFEGDSIVLKCQGE---QNWKIQKMAYHKDNKELSVFKKFSDF 67
VTE TL+A VF G S++L+CQG + + + H + SV +DF
Sbjct: 868 VTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADF 927
Query: 68 LIQSAVLSDSGNYFC-------STKGQLFLWDKTSNIVKIKVQELFQRPVLTA--SSFQP 118
L+ + DSGNY C S +G S + I V + F +P L A SS P
Sbjct: 928 LLHTVGAEDSGNYSCIYYETTMSNRGSYL-----SMPLMIWVTDTFPKPWLFAEPSSVVP 982
Query: 119 IEGGPVSLKCETRLSPQRLDVQLQFCFFRENQV----LGSGWSSSPELQISAVWSEDTGS 174
+ G V+L C + + + +E + L S+ I+ + G
Sbjct: 983 M-GQNVTLWCRGPVH------GVGYILHKEGEATSMQLWGSTSNDGAFPITNISGTSMGR 1035
Query: 175 YWCKAE---TVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGG 231
Y C T + +I+ + + +P ++ + PG V G+ + L C G
Sbjct: 1036 YSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSL---LAQPGPMVAPGENMTLQCQ--GE 1090
Query: 232 TGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPI----QSK 287
+ TF +E + ++ A+ +PAV+ D+G Y C P S
Sbjct: 1091 LPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSD 1150
Query: 288 VVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGS-PPILYQFYHEDVTLGNSSA 346
+ I V +P L+ P +G + L C RG P + + H+ +
Sbjct: 1151 SLEIWVTDKPPKPSLS-AWPSTMFKLGKDITLQC---RGPLPGVEFVLEHDGEEAPQQFS 1206
Query: 347 PSGGGASFNLSLTAEHSGNYSC 368
G N+ + GNYSC
Sbjct: 1207 EDGDFVINNVE--GKGIGNYSC 1226
Score = 45.8 bits (107), Expect = 9e-05
Identities = 84/352 (23%), Positives = 137/352 (38%), Gaps = 51/352 (14%)
Query: 67 FLIQSAVLSDSGNYFCSTKGQLF--LWDKTSNIVKIKVQELFQRPVLTASSFQPI--EGG 122
F I + D G Y C T Q+ LW + SN +K+ V L+ +P LTA PI G
Sbjct: 184 FSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHP-GPIMAPGE 242
Query: 123 PVSLKCETRLSPQRLDV----QLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCK 178
++L+C+ + + L+ F+ + + L+I +DTG Y C
Sbjct: 243 SLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKI-----QDTGHYLCF 297
Query: 179 AETVTHRIRKQSLQSQIHVQRIPISNV---SLEIRAPGGQVTEGQKLILLCSVAGGTGNV 235
++R SL S V +I +++ + + P V GQ + L C G V
Sbjct: 298 YYDASYR---GSLLSD--VLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRC--RGPVDGV 350
Query: 236 TFSWYREATGTSMGKKTQRSL--SAELEIPAVKESDAGKYYCR---------ADNGHVPI 284
+ Y++ + S+ + + V SD G Y C H +
Sbjct: 351 GLALYKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTV 410
Query: 285 QSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNS 344
+ VV+ P + +S P +G + L C R S P+L +F E
Sbjct: 411 ELMVVDKPPKPSLS------AWPSTVFKLGKAITLQC---RVSHPVL-EFSLEWEERETF 460
Query: 345 SAPSGGGASFNLSLTAEHSGNYSC----EANNGLGAQCSEAVPVSISGPDGY 392
S G ++ + +G YSC E + + + SE P+ + GP GY
Sbjct: 461 QKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSE--PLKLMGPAGY 510
Score = 40.8 bits (94), Expect = 0.003
Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 15/108 (13%)
Query: 31 GDSIVLKCQGE---------QNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSDSGNYF 81
G+S+ L+CQG + ++K YHK K ++F QS + D+G+Y
Sbjct: 241 GESLNLRCQGPIYGMTFALMRVEDLEKSFYHK-----KTIKNEANFFFQSLKIQDTGHYL 295
Query: 82 CSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIE-GGPVSLKC 128
C + S+++KI V + F + L A ++ G VSL+C
Sbjct: 296 CFYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRC 343
Score = 33.5 bits (75), Expect = 0.47
Identities = 78/362 (21%), Positives = 142/362 (39%), Gaps = 50/362 (13%)
Query: 25 PSSVFE-GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFS---DFLIQSAVLSDSGNY 80
PS+VF+ G +I L+C+ + + + +E F+KFS DF+I + +G Y
Sbjct: 427 PSTVFKLGKAITLQCRVSH----PVLEFSLEWEERETFQKFSVNGDFIISNVDGKGTGTY 482
Query: 81 FCSTKGQLF--LWDKTSNIVKIK--VQELFQRPVLTASSFQPIEGGPVSLKCET---RLS 133
CS + + +W S +K+ L VL + + V+L R
Sbjct: 483 SCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIRWK 542
Query: 134 PQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAET-VTHRIRKQSLQ 192
+RL + RE +LG+ + ++A+ + ET + K L
Sbjct: 543 CRRLRI-------REAWLLGTAQGVTMLFIVTALLCCGLCNGVLIEETEIVMPTPKPELW 595
Query: 193 SQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKT 252
++ + P N++L R+P G E F ++ TG +
Sbjct: 596 AETNFPLAPWKNLTLWCRSPSGSTKE------------------FVLLKDGTGWIATRPA 637
Query: 253 QRSLSAELEIPAVKESDAGKYYCRA-DNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQA 311
+ A + A+ +S G Y+C + + V S+ + + + +PV++ SP +
Sbjct: 638 SEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDILPKPVIS-ASPTIR- 695
Query: 312 AVGDLLELHCEA-LRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLS-LTAEHSGNYSCE 369
G L+L C+ L G LY+ ++ G A F + + + GNYSC
Sbjct: 696 --GQELQLRCKGWLAGMGFALYKEGEQEPV--QQLGAVGREAFFTIQRMEDKDEGNYSCR 751
Query: 370 AN 371
+
Sbjct: 752 TH 753
Score = 33.1 bits (74), Expect = 0.61
Identities = 50/239 (20%), Positives = 86/239 (35%), Gaps = 40/239 (16%)
Query: 153 GSGWSSS--------PELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISN 204
G+GW ++ + A+ TGSY C H + ++ + ++
Sbjct: 628 GTGWIATRPASEQVRAAFPLGALTQSHTGSYHC------HSWEEMAVSEPSEALELVGTD 681
Query: 205 VSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPA 264
+ + GQ+L L C G + F+ Y+E + + A I
Sbjct: 682 ILPKPVISASPTIRGQELQLRCK--GWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQR 739
Query: 265 VKESDAGKYYCRADNGHVPIQSKVVNIPVRIPV------------SRPVLTLRSPGAQAA 312
+++ D G Y CR P + + P+ + + + PV+T PGA+
Sbjct: 740 MEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVT---PGAR-- 794
Query: 313 VGDLLELHCEALRGSPP-ILYQFYHEDVTLGNSSAPSGGGASFNL--SLTAEHSGNYSC 368
+ +C ILY+ E + S A G A+ L S+ GNYSC
Sbjct: 795 ----VTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSC 849
Score = 33.1 bits (74), Expect = 0.61
Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 13 VTEQADSLTLVA-PSSVFE-GDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQ 70
VT++ +L A PS++F+ G I L+C+G ++ + H + F + DF+I
Sbjct: 1156 VTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPG-VEFVLEHDGEEAPQQFSEDGDFVIN 1214
Query: 71 SAVLSDSGNYFCSTKGQLF--LWDKTSNIVKI 100
+ GNY CS + Q + +W + S+ +++
Sbjct: 1215 NVEGKGIGNYSCSYRLQAYPDIWSEPSDPLEL 1246
>gi|142976733 surface glycoprotein, Ig superfamily member [Homo
sapiens]
Length = 1264
Score = 60.8 bits (146), Expect = 3e-09
Identities = 63/249 (25%), Positives = 109/249 (43%), Gaps = 15/249 (6%)
Query: 159 SPELQISAVWSEDTGSYWCKA-ETVTHRIRKQSLQSQIHVQRIPISNVSL--EIRAPGGQ 215
S LQI V ED GSY C A VTH+++ + + ++ V R +V + +
Sbjct: 173 SGNLQILNVSLEDKGSYKCAAYNPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALA 232
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYC 275
V + L C V+G + W ++ + G +R L + L +V +D+G Y C
Sbjct: 233 VLSRSPVTLECVVSGVPAPQVY-WLKDGQDIAPGSNWRR-LYSHLATDSVDPADSGNYSC 290
Query: 276 RADN--GHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQ 333
A N G V + +VN+ +S+ + ++G + C+ + G+P
Sbjct: 291 MAGNKSGDVKYVTYMVNVLEHASISKGL-----QDQIVSLGATVHFTCD-VHGNPAPNCT 344
Query: 334 FYHEDVTLGNSSAPSGGGASFNLS-LTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGY 392
++H + S+ G +S +T E G Y C A+NG+G S + I G+
Sbjct: 345 WFHNAQPIHPSARHLTAGNGLKISGVTVEDVGMYQCVADNGIGFMHSTG-RLEIENDGGF 403
Query: 393 RRDLMTAGV 401
+ ++TA V
Sbjct: 404 KPVIITAPV 412
Score = 46.2 bits (108), Expect = 7e-05
Identities = 69/293 (23%), Positives = 111/293 (37%), Gaps = 51/293 (17%)
Query: 123 PVSLKCETRLSPQRLDVQLQFCFFRENQVL--GSGWSSS-PELQISAVWSEDTGSYWCKA 179
PV+L+C P Q + ++ Q + GS W L +V D+G+Y C A
Sbjct: 238 PVTLECVVSGVPAP-----QVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMA 292
Query: 180 ETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSW 239
+ ++ + + + + S+ V+ G + C V G +W
Sbjct: 293 GNKSGDVKYVTYMVNV------LEHASISKGLQDQIVSLGATVHFTCDVHGNPAP-NCTW 345
Query: 240 YREATGTSMGKKTQRSLSAE--LEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPV 297
+ A + R L+A L+I V D G Y C ADNG + + +
Sbjct: 346 FHNAQPIH---PSARHLTAGNGLKISGVTVEDVGMYQCVADNG-IGFMHSTGRLEIENDG 401
Query: 298 S-RPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFY--------HEDVTLGNSSAPS 348
+PV+ A+ A GD + L C A G P + ++Y H L + S S
Sbjct: 402 GFKPVIITAPVSAKVADGDFVTLSCNA-SGLPVPVIRWYDSHGLITSHPSQVLRSKSRKS 460
Query: 349 -------------------GGGASFNL-SLTAEHSGNYSCEANNGLGAQCSEA 381
G +S ++ ++T EH+G Y CEA N G +EA
Sbjct: 461 QLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEA 513
Score = 33.5 bits (75), Expect = 0.47
Identities = 46/180 (25%), Positives = 67/180 (37%), Gaps = 42/180 (23%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVS----LEIRAP-GGQV 216
L+IS V ED G Y C A+ + R+ I N + I AP +V
Sbjct: 365 LKISGVTVEDVGMYQCVADN--------GIGFMHSTGRLEIENDGGFKPVIITAPVSAKV 416
Query: 217 TEGQKLILLCSVAGGTGNVTFSWYREATGT----------SMGKKTQRSL---------- 256
+G + L C+ A G WY ++ G S +K+Q S
Sbjct: 417 ADGDFVTLSCN-ASGLPVPVIRWY-DSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVY 474
Query: 257 -------SAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGA 309
++ L I AV + AGKY C A N H Q++ + V + T+ P A
Sbjct: 475 FVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLMVVPFETNTKAETVTLPDA 534
Score = 30.8 bits (68), Expect = 3.0
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query: 300 PVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTL-GN-SSAPSGGGASFNLS 357
P T A +G + LHC A + I + H TL GN G LS
Sbjct: 29 PYFTSEPLSAVQKLGGPVVLHCSAQPVTTRI--SWLHNGKTLDGNLEHVKIHQGTLTILS 86
Query: 358 LTAEHSGNYSCEANNGLGAQCSEAVPVSIS 387
L + G Y C ANN +GA S VS++
Sbjct: 87 LNSSLLGYYQCLANNSIGAIVSGPATVSVA 116
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 60.1 bits (144), Expect = 5e-09
Identities = 57/223 (25%), Positives = 86/223 (38%), Gaps = 26/223 (11%)
Query: 69 IQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKC 128
+ A L D G YFC QL+ D I + V + PV+ Q +EGG V L C
Sbjct: 91 LSDARLEDEGGYFC----QLYTEDTHHQIATLTVLVAPENPVVEVRE-QAVEGGEVELSC 145
Query: 129 ETRLSPQRLDVQLQFCFFRENQVL---------GSGWSSSPELQISAVWSEDTGSYWCKA 179
S ++ ++R+ + L G WS + ++ +D G C+A
Sbjct: 146 LVPRSRPAATLR----WYRDRKELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEA 201
Query: 180 ET-VTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFS 238
+ + Q + VQ P + I A V EG L+L C+V G
Sbjct: 202 QNQALPSGHSKQTQYVLDVQYSPTAR----IHASQAVVREGDTLVLTCAVTGNPRPNQIR 257
Query: 239 WYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGH 281
W R G + ++ L +P + +D G Y C A N H
Sbjct: 258 WNR---GNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKH 297
Score = 51.6 bits (122), Expect = 2e-06
Identities = 70/290 (24%), Positives = 122/290 (42%), Gaps = 30/290 (10%)
Query: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPIS--NVSLEIRAPGGQVTEG 219
+++S ED G Y+C+ T + QI + ++ N +E+R Q EG
Sbjct: 89 IRLSDARLEDEGGYFCQLYT-------EDTHHQIATLTVLVAPENPVVEVRE---QAVEG 138
Query: 220 QKLILLCSVAGGTGNVTFSWYR---EATGTSMGKKTQR--SLSAELEIPAVKESDAGKYY 274
++ L C V T WYR E G S ++ + S+++ + ++ D G
Sbjct: 139 GEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIII 198
Query: 275 CRADNGHVPI-QSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQ 333
C A N +P SK + + S P + + A GD L L C A+ G+P
Sbjct: 199 CEAQNQALPSGHSKQTQYVLDVQYS-PTARIHASQAVVREGDTLVLTC-AVTGNPRPNQI 256
Query: 334 FYHEDVTLGNSSAPSGG---GASFNL-SLTAEHSGNYSCEANNGLG-AQCSEAVPVSISG 388
++ GN S P G + L L + +G Y+CEA+N G A+ + V G
Sbjct: 257 RWNR----GNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPG 312
Query: 389 PDGYRRDLMTAGVLWGLFGVLGFTGVALLLYALFHKISGESS-ATNEPRG 437
+ + ++ G+ +L F + +L+ ++ + + S T+E G
Sbjct: 313 AVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEASG 362
>gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens]
Length = 697
Score = 59.7 bits (143), Expect = 6e-09
Identities = 84/299 (28%), Positives = 128/299 (42%), Gaps = 46/299 (15%)
Query: 148 ENQVLGSG--WSSSP-ELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQ------ 198
+N+VL S W P L++ V + D+G Y C+AE +R+ Q + VQ
Sbjct: 291 QNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAE---NRLGSQQRALDLSVQYPPENL 347
Query: 199 RIPISNVSLEIRAPGGQ-----VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQ 253
R+ +S + + G V EGQ L L+C V + SW + S +Q
Sbjct: 348 RVMVSQANRTVLENLGNGTSLPVLEGQSLCLVC-VTHSSPPARLSWTQRGQVLS---PSQ 403
Query: 254 RSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAV 313
S LE+P V+ G++ C A + P+ S+ V++ + + S P L S +A
Sbjct: 404 PSDPGVLELPRVQVEHEGEFTCHARH---PLGSQHVSLSLSVHYS-PKLLGPSCSWEA-- 457
Query: 314 GDLLELHCEALRGSPPILYQFYHEDVTLGNSS------APSGGGASFNLSLTAEHSGNYS 367
+ L C + P L + E++ GNSS PS G N SL+ H G S
Sbjct: 458 -EGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSAGPWANSSLSL-HGGLSS 515
Query: 368 -----CEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLLYAL 421
CEA N GAQ + + PD ++ L++ G F +G T + L AL
Sbjct: 516 GLRLRCEAWNVHGAQSGSILQL----PD--KKGLISTAFSNGAFLGIGITALLFLCLAL 568
Score = 52.8 bits (125), Expect = 7e-07
Identities = 60/207 (28%), Positives = 85/207 (41%), Gaps = 24/207 (11%)
Query: 215 QVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKT-QRSLSAELEIPAVKESDAGKY 273
+ +GQ L LLC+ A T SW + S R L LE+P VK D+G+Y
Sbjct: 265 EAQKGQFLRLLCA-ADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRY 321
Query: 274 YCRADNGHVPIQSKVVNIPVRIP----------VSRPVLTLRSPGAQAAV--GDLLELHC 321
CRA+N + Q + +++ V+ P +R VL G V G L L C
Sbjct: 322 TCRAEN-RLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVC 380
Query: 322 EALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEA 381
SPP + L + S PS G + EH G ++C A + LG+Q
Sbjct: 381 -VTHSSPPARLSWTQRGQVL-SPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQ---- 434
Query: 382 VPVSISGPDGYRRDLMTAGVLWGLFGV 408
VS+S Y L+ W G+
Sbjct: 435 -HVSLSLSVHYSPKLLGPSCSWEAEGL 460
>gi|146229333 hypothetical protein LOC284021 [Homo sapiens]
Length = 343
Score = 58.9 bits (141), Expect = 1e-08
Identities = 57/225 (25%), Positives = 96/225 (42%), Gaps = 10/225 (4%)
Query: 216 VTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYC 275
V +GQ + + CS + +T+S +R T +G + + A + + ++G Y C
Sbjct: 46 VMKGQNVSMFCSHKNKSLQITYSLFRRKT--HLGTQDGKGEPAIFNLSITEAHESGPYKC 103
Query: 276 RADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFY 335
+A S+ + + PV+ PVL + Q + LHC ++ GS PI Y F+
Sbjct: 104 KAQVTSCSKYSRDFSFTIVDPVTSPVLNIMV--IQTETDRHITLHCLSVNGSLPINYTFF 161
Query: 336 HEDVTLGNS-SAPSGGGASFNLSLTAEHSG---NYSCEANNGLGAQCSEAVPVSISGPDG 391
V + + S A FN LT ++ G Y CEA N L + + PV++ G
Sbjct: 162 ENHVAISPAISKYDREPAEFN--LTKKNPGEEEEYRCEAKNRLPNYATYSHPVTMPSTGG 219
Query: 392 YRRDLMTAGVLWGLFGVLGFTGVALLLYALFHKISGESSATNEPR 436
+L GL +L + L + L + ++ N PR
Sbjct: 220 DSCPFCLKLLLPGLLLLLVVIILILAFWVLPKYKTRKAMRNNVPR 264
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,296,933
Number of Sequences: 37866
Number of extensions: 958605
Number of successful extensions: 4884
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 273
Number of HSP's that attempted gapping in prelim test: 3128
Number of HSP's gapped (non-prelim): 1296
length of query: 508
length of database: 18,247,518
effective HSP length: 107
effective length of query: 401
effective length of database: 14,195,856
effective search space: 5692538256
effective search space used: 5692538256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.