Guide to the Human Genome
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Search of human proteins with 19923352

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923352 NK3 homeobox 1 [Homo sapiens]
         (234 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923352 NK3 homeobox 1 [Homo sapiens]                             476   e-135
gi|4502365 NK3 homeobox 2 [Homo sapiens]                              123   1e-28
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap...    93   2e-19
gi|31377777 NK2 homeobox 8 [Homo sapiens]                              92   4e-19
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap...    88   7e-18
gi|14149728 BarH-like homeobox 1 [Homo sapiens]                        87   9e-18
gi|118766339 thyroid transcription factor 1 isoform 1 [Homo sapi...    86   2e-17
gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]     86   2e-17
gi|157426823 NK2 homeobox 4 [Homo sapiens]                             86   4e-17
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]    82   3e-16
gi|39930383 BarH-like homeobox 2 [Homo sapiens]                        82   4e-16
gi|4506049 hematopoietically expressed homeobox [Homo sapiens]         80   1e-15
gi|226437602 NK1 homeobox 2 [Homo sapiens]                             80   2e-15
gi|70608170 H6 family homeobox 2 [Homo sapiens]                        79   3e-15
gi|116805350 homeo box (H6 family) 1 [Homo sapiens]                    79   4e-15
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  78   6e-15
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  78   6e-15
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  78   6e-15
gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]    78   6e-15
gi|19923391 homeobox D3 [Homo sapiens]                                 77   1e-14
gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]                  77   1e-14
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]                   77   1e-14
gi|89257348 homeo box HB9 [Homo sapiens]                               77   1e-14
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]              77   2e-14
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  76   3e-14
gi|24497513 homeobox A3 isoform a [Homo sapiens]                       75   5e-14
gi|13562112 homeobox A3 isoform a [Homo sapiens]                       75   5e-14
gi|157743259 H6 family homeobox 3 [Homo sapiens]                       75   5e-14
gi|27886557 msh homeobox 2 [Homo sapiens]                              75   5e-14
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]                   75   5e-14

>gi|19923352 NK3 homeobox 1 [Homo sapiens]
          Length = 234

 Score =  476 bits (1226), Expect = e-135
 Identities = 234/234 (100%), Positives = 234/234 (100%)

Query: 1   MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEP 60
           MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEP
Sbjct: 1   MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEP 60

Query: 61  EPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTP 120
           EPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTP
Sbjct: 61  EPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTP 120

Query: 121 KQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTK 180
           KQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTK
Sbjct: 121 KQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTK 180

Query: 181 RKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSWSPAFW 234
           RKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSWSPAFW
Sbjct: 181 RKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSWSPAFW 234


>gi|4502365 NK3 homeobox 2 [Homo sapiens]
          Length = 333

 Score =  123 bits (309), Expect = 1e-28
 Identities = 86/217 (39%), Positives = 109/217 (50%), Gaps = 48/217 (22%)

Query: 32  QDILRDGAQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEEAET-L 90
           +D+  + A R     S+    D  P  E +  G R   GA    L +G           +
Sbjct: 136 KDLEEEAAGRSDSEMSASVSGDRSPRTEDDGVGPR---GAHVSALCSGAGGGGGSGPAGV 192

Query: 91  AETEPERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLS 150
           AE E E                    P  PK  +KRSRAAFSH QV ELER+F+HQ+YLS
Sbjct: 193 AEEEEE--------------------PAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLS 232

Query: 151 APERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKE-------- 202
            PERA LA +LKLTETQVKIWFQNRRYKTKR+Q++++L      +S PA K+        
Sbjct: 233 GPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADL-----LASAPAAKKVAVKVLVR 287

Query: 203 ---------EAFSRASLVSVYNSYPYYPYLYCVGSWS 230
                    E     SL+ +  SY YYPY YC+  W+
Sbjct: 288 DDQRQYLPGEVLRPPSLLPLQPSY-YYPY-YCLPGWA 322


>gi|148746211 NK2 transcription factor related, locus 3 [Homo
           sapiens]
          Length = 364

 Score = 92.8 bits (229), Expect = 2e-19
 Identities = 62/165 (37%), Positives = 81/165 (49%), Gaps = 27/165 (16%)

Query: 84  PEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTPKQPQKRSR----AAFSHTQVIEL 139
           P+E E   E   +R   S  L     +    +  +  ++P+ RSR      FS  QV EL
Sbjct: 104 PKEHEEEPEVVRDRSQKSCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFEL 163

Query: 140 ERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPA 199
           ER+F  Q+YLSAPER HLA +LKLT TQVKIWFQNRRYK KR++    L +L  H+  P 
Sbjct: 164 ERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSL-ELGAHAPPPP 222

Query: 200 LKEEA----------------------FSRASLVSVYNSYPYYPY 222
            +  A                      +S  +    YNS+P Y Y
Sbjct: 223 PRRVAVPVLVRDGKPCVTPSAQAYGAPYSVGASAYSYNSFPAYGY 267


>gi|31377777 NK2 homeobox 8 [Homo sapiens]
          Length = 239

 Score = 92.0 bits (227), Expect = 4e-19
 Identities = 60/152 (39%), Positives = 78/152 (51%), Gaps = 20/152 (13%)

Query: 51  QRDPEPE-PEPEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENT 109
           +R+PEP  P+P+P             L +     P   E+  ET P         DS   
Sbjct: 27  RREPEPRAPQPDPCAA---------WLDSERGHYPSSDESSLETSPP--------DSSQR 69

Query: 110 SGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVK 169
             A P  P +  + +K+ R  FS  Q +ELER+F  Q+YLSAPER  LA  L+LT TQVK
Sbjct: 70  PSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVK 129

Query: 170 IWFQNRRYKTKRKQL--SSELGDLEKHSSLPA 199
           IWFQN RYK KR +   ++E  DL   + L A
Sbjct: 130 IWFQNHRYKLKRARAPGAAESPDLAASAELHA 161


>gi|210147470 NK2 transcription factor related, locus 6 [Homo
           sapiens]
          Length = 219

 Score = 87.8 bits (216), Expect = 7e-18
 Identities = 49/104 (47%), Positives = 64/104 (61%), Gaps = 6/104 (5%)

Query: 95  PERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPER 154
           PER +G+     ++  G   R  Q   + +++ R  FS  QV+ LER+F  Q+YLSAPER
Sbjct: 26  PERGVGN---SGDSVRGG--RSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPER 80

Query: 155 AHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLP 198
            HLA  L+LT TQVKIWFQNRRYK KR++    L +L  H   P
Sbjct: 81  EHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSL-ELAGHPLTP 123


>gi|14149728 BarH-like homeobox 1 [Homo sapiens]
          Length = 327

 Score = 87.4 bits (215), Expect = 9e-18
 Identities = 71/194 (36%), Positives = 93/194 (47%), Gaps = 29/194 (14%)

Query: 2   LRVPEPRPGEAKAEGA---------APPTPSKPLTS-FLIQDILRDGAQRQGGRTSSQRQ 51
           L    PRPG A   G          + P  S+ +TS FLI+DIL D          S   
Sbjct: 59  LETGTPRPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSG 118

Query: 52  RDPEPEPEPEPEGGRSRAGAQND---QLSTGPRAAPEEAETLAETEPERHLGSYLLDSEN 108
           +   PEP     GGR  A A  D   +L      A  ++E   + E +R + S   DS  
Sbjct: 119 QPAAPEP-----GGRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSR-DSP- 171

Query: 109 TSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQV 168
                   P   K+P+K +R AF+  Q+ +LER F  QKYLS  +R  LA +L LT+TQV
Sbjct: 172 --------PVRLKKPRK-ARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQV 222

Query: 169 KIWFQNRRYKTKRK 182
           K W+QNRR K KR+
Sbjct: 223 KTWYQNRRTKWKRQ 236


>gi|118766339 thyroid transcription factor 1 isoform 1 [Homo
           sapiens]
          Length = 401

 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 40/63 (63%), Positives = 46/63 (73%)

Query: 120 PKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKT 179
           P  P+++ R  FS  QV ELER+F  QKYLSAPER HLA  + LT TQVKIWFQN RYK 
Sbjct: 187 PSAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKM 246

Query: 180 KRK 182
           KR+
Sbjct: 247 KRQ 249


>gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]
          Length = 371

 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 40/63 (63%), Positives = 46/63 (73%)

Query: 120 PKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKT 179
           P  P+++ R  FS  QV ELER+F  QKYLSAPER HLA  + LT TQVKIWFQN RYK 
Sbjct: 157 PSAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKM 216

Query: 180 KRK 182
           KR+
Sbjct: 217 KRQ 219


>gi|157426823 NK2 homeobox 4 [Homo sapiens]
          Length = 354

 Score = 85.5 bits (210), Expect = 4e-17
 Identities = 41/75 (54%), Positives = 49/75 (65%)

Query: 123 PQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRK 182
           P+++ R  FS  QV ELER+F  QKYLSAPER HLA  + LT TQVKIWFQN RYK KR+
Sbjct: 188 PRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ 247

Query: 183 QLSSELGDLEKHSSL 197
                   L++   L
Sbjct: 248 AKDKAAQQLQQEGGL 262


>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
          Length = 324

 Score = 82.4 bits (202), Expect = 3e-16
 Identities = 40/65 (61%), Positives = 47/65 (72%)

Query: 124 QKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQ 183
           +++ R  FS  QV ELER+F  Q+YLSAPER  LA  LKLT TQVKIWFQNRRYK KR++
Sbjct: 138 RRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQR 197

Query: 184 LSSEL 188
               L
Sbjct: 198 QDQTL 202


>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
          Length = 387

 Score = 82.0 bits (201), Expect = 4e-16
 Identities = 69/231 (29%), Positives = 104/231 (45%), Gaps = 29/231 (12%)

Query: 6   EPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPEP--- 62
           +P P   +  G+A   P    +SFLI+DIL D          S     P   P+ E    
Sbjct: 119 QPPPPPPQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAV 178

Query: 63  -EGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTPK 121
            E  R +   ++ +     R   E++++  +    +  G   + S   S      P   K
Sbjct: 179 HESFRPKLEQEDSKTKLDKR---EDSQSDIKCHGTKEEGDREITSSRESP-----PVRAK 230

Query: 122 QPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKR 181
           +P+K +R AFS  Q+ +LER F  QKYLS  +R  LA  L LT+TQVK W+QNRR K KR
Sbjct: 231 KPRK-ARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKR 289

Query: 182 K-----QLSSELGDLEK-----------HSSLPALKEEAFSRASLVSVYNS 216
           +     +L +E G+              H SL    +   + A+  ++Y+S
Sbjct: 290 QTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSS 340


>gi|4506049 hematopoietically expressed homeobox [Homo sapiens]
          Length = 270

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 80/236 (33%), Positives = 93/236 (39%), Gaps = 40/236 (16%)

Query: 7   PRPGEAKAEGAAPPTPSKPL------TSFLIQDILRDG-----------AQRQGGRTSSQ 49
           P PG A      P     PL      T F I+DIL  G           +      +   
Sbjct: 4   PHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTSLVS 63

Query: 50  RQRDPEPEPEP-EPEGGRSRAGAQNDQLSTG---------PRAAPEEAETLAETEPERHL 99
             R P  EP P  P      A A       G         PR   +    L   +P   L
Sbjct: 64  PYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDP---L 120

Query: 100 GSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAK 159
           G  LL S       P L Q P   +K  +  FS+ Q IELE+KF  QKYLS PER  LAK
Sbjct: 121 GKPLLWS-------PFL-QRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAK 172

Query: 160 NLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYN 215
            L+L+E QVK WFQNRR K +R  L  E     K   L +L      R  L S  N
Sbjct: 173 MLQLSERQVKTWFQNRRAKWRR--LKQENPQSNKKEELESLDSSCDQRQDLPSEQN 226


>gi|226437602 NK1 homeobox 2 [Homo sapiens]
          Length = 310

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 61/181 (33%), Positives = 85/181 (46%), Gaps = 8/181 (4%)

Query: 6   EPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPEPEGG 65
           E R   A+ E     +   P+      D    GA +      S+ + + + E +P     
Sbjct: 45  EARKSLAEVEAGKDASSRDPVRQLETPDAAGPGAGQASPLEGSEAEEEEDAE-DPRRPRL 103

Query: 66  RSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTPKQPQ- 124
           R RA      L+  P A    A  LA  EP    G   + S   S   PR  +   +P  
Sbjct: 104 RERAARLLPGLARSPDAP---AGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNC 160

Query: 125 ---KRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKR 181
              +R+R AF++ Q++ LE KF   +YLS  ER +LA +L LTETQVKIWFQNRR K K+
Sbjct: 161 AKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK 220

Query: 182 K 182
           +
Sbjct: 221 Q 221


>gi|70608170 H6 family homeobox 2 [Homo sapiens]
          Length = 273

 Score = 79.3 bits (194), Expect = 3e-15
 Identities = 67/192 (34%), Positives = 88/192 (45%), Gaps = 21/192 (10%)

Query: 9   PGEAKAEGAAPPTPSKPLTSFLIQDILRDG--------AQRQGGRTSSQRQRDPEPEP-- 58
           P EA  E    P   + L+    ++   DG          + G +    +   P P P  
Sbjct: 30  PSEAPREPVGWPARKRSLSVSSEEEEPDDGWKAPACFCPDQHGPKEQGPKHHPPIPFPCL 89

Query: 59  -EPEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENT-SGALPRL 116
             P+  GG    G     L   P  +P  ++   E E     GS    SE    G   R 
Sbjct: 90  GTPKGSGGSGPGG-----LERTPFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGAERQ 144

Query: 117 PQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRR 176
               K   K++R  FS +QV +LE  F  ++YLS+ ERA LA +L+LTETQVK WFQNRR
Sbjct: 145 AGAAK---KKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRR 201

Query: 177 YKTKRKQLSSEL 188
            K KR QLS+EL
Sbjct: 202 NKWKR-QLSAEL 212


>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
          Length = 348

 Score = 78.6 bits (192), Expect = 4e-15
 Identities = 59/148 (39%), Positives = 75/148 (50%), Gaps = 9/148 (6%)

Query: 43  GGRTSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHL--G 100
           GG +     RD    PE   E GR+           GP A   EA  LA   P       
Sbjct: 126 GGLSPDTSDRD---SPETGEEMGRAEGAWPR---GPGPGAVQREAAELAARGPAAGTEEA 179

Query: 101 SYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKN 160
           S L +    +G            +K++R  FS +QV +LE  F  ++YLS+ ERA LA +
Sbjct: 180 SELAEVPAAAGETRGGVGVGGGRKKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAAS 239

Query: 161 LKLTETQVKIWFQNRRYKTKRKQLSSEL 188
           L+LTETQVKIWFQNRR K KR QL++EL
Sbjct: 240 LQLTETQVKIWFQNRRNKWKR-QLAAEL 266



 Score = 34.3 bits (77), Expect = 0.095
 Identities = 31/115 (26%), Positives = 42/115 (36%), Gaps = 11/115 (9%)

Query: 9   PGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPEPEGGRSR 68
           P E    G A P  +   +SFLI+++L   A+  G  T     R+ E E + +PE     
Sbjct: 2   PDELTEPGRATPARA---SSFLIENLLAAEAKGAGRATQGDGSREDEEEDDDDPE----- 53

Query: 69  AGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTPKQP 123
                D      R      + LA T P     +  L      G  PR P  P  P
Sbjct: 54  ---DEDAEQARRRRLQRRRQLLAGTGPGGEARARALLGPGALGLGPRPPPGPGPP 105


>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 78.2 bits (191), Expect = 6e-15
 Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 6/152 (3%)

Query: 36  RDGAQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEE-AETLAETE 94
           RD A    G+ S     + E E + E +  R R   +  +L  G   +P+  A  LA  E
Sbjct: 93  RDAAGPGAGQASPLEGSEAEEEEDAE-DPRRPRLRERAARLLPGLARSPDAPAGALASGE 151

Query: 95  PERHLGSYLLDSENTSGALPRLPQTPKQPQ----KRSRAAFSHTQVIELERKFSHQKYLS 150
           P    G   + S   S   PR  +   +P     +R+R AF++ Q++ LE KF   +YLS
Sbjct: 152 PCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLS 211

Query: 151 APERAHLAKNLKLTETQVKIWFQNRRYKTKRK 182
             ER +LA +L LTETQVKIWFQNRR K K++
Sbjct: 212 VCERLNLALSLSLTETQVKIWFQNRRTKWKKQ 243


>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 78.2 bits (191), Expect = 6e-15
 Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 6/152 (3%)

Query: 36  RDGAQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEE-AETLAETE 94
           RD A    G+ S     + E E + E +  R R   +  +L  G   +P+  A  LA  E
Sbjct: 93  RDAAGPGAGQASPLEGSEAEEEEDAE-DPRRPRLRERAARLLPGLARSPDAPAGALASGE 151

Query: 95  PERHLGSYLLDSENTSGALPRLPQTPKQPQ----KRSRAAFSHTQVIELERKFSHQKYLS 150
           P    G   + S   S   PR  +   +P     +R+R AF++ Q++ LE KF   +YLS
Sbjct: 152 PCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLS 211

Query: 151 APERAHLAKNLKLTETQVKIWFQNRRYKTKRK 182
             ER +LA +L LTETQVKIWFQNRR K K++
Sbjct: 212 VCERLNLALSLSLTETQVKIWFQNRRTKWKKQ 243


>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 78.2 bits (191), Expect = 6e-15
 Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 6/152 (3%)

Query: 36  RDGAQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEE-AETLAETE 94
           RD A    G+ S     + E E + E +  R R   +  +L  G   +P+  A  LA  E
Sbjct: 93  RDAAGPGAGQASPLEGSEAEEEEDAE-DPRRPRLRERAARLLPGLARSPDAPAGALASGE 151

Query: 95  PERHLGSYLLDSENTSGALPRLPQTPKQPQ----KRSRAAFSHTQVIELERKFSHQKYLS 150
           P    G   + S   S   PR  +   +P     +R+R AF++ Q++ LE KF   +YLS
Sbjct: 152 PCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLS 211

Query: 151 APERAHLAKNLKLTETQVKIWFQNRRYKTKRK 182
             ER +LA +L LTETQVKIWFQNRR K K++
Sbjct: 212 VCERLNLALSLSLTETQVKIWFQNRRTKWKKQ 243


>gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]
          Length = 273

 Score = 78.2 bits (191), Expect = 6e-15
 Identities = 36/58 (62%), Positives = 43/58 (74%)

Query: 124 QKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKR 181
           +++ R  FS  Q  ELER+F  Q+YLSAPER HLA  ++LT TQVKIWFQN RYK KR
Sbjct: 128 KRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKR 185


>gi|19923391 homeobox D3 [Homo sapiens]
          Length = 432

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 50/151 (33%), Positives = 68/151 (45%), Gaps = 5/151 (3%)

Query: 38  GAQRQGGRTSSQRQRDPEPEPEPEPEGGRSR--AGAQNDQLSTGPRAAPEEAETLAETEP 95
           G  +  G  S Q+   P P P   P    +    G    +   GP A+   A    +  P
Sbjct: 103 GGSQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFP 162

Query: 96  ---ERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAP 152
              E    S   +S  T+G        P    KR R A++  Q++ELE++F   +YL  P
Sbjct: 163 WMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRP 222

Query: 153 ERAHLAKNLKLTETQVKIWFQNRRYKTKRKQ 183
            R  +A  L LTE Q+KIWFQNRR K K+ Q
Sbjct: 223 RRVEMANLLNLTERQIKIWFQNRRMKYKKDQ 253


>gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]
          Length = 291

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 41/96 (42%), Positives = 63/96 (65%), Gaps = 2/96 (2%)

Query: 114 PRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQ 173
           P   +TP + +K+ R +FS  Q+ ELE++F  QKYL++ ERA LAK+LK+T+ QVK WFQ
Sbjct: 157 PYQNRTPPK-RKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQ 215

Query: 174 NRRYKTKRKQLSSELGDLEKHSSLP-ALKEEAFSRA 208
           NRR K +R+       + ++ S L   L+ +AF ++
Sbjct: 216 NRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKS 251


>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
          Length = 284

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 44/97 (45%), Positives = 67/97 (69%), Gaps = 6/97 (6%)

Query: 114 PRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQ 173
           P   +TP + +K+ R +FS +QV+ELER+F  QKYL++ ERA LAK L++T+ QVK WFQ
Sbjct: 148 PYQNRTPPK-RKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQ 206

Query: 174 NRRYKTKRKQLSSELGDLEKHSS---LPALKEEAFSR 207
           NRR K +R+  ++E  + E+H +   L  L+++A  R
Sbjct: 207 NRRTKWRRQ--TAEEREAERHRAGRLLLHLQQDALPR 241


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 45/99 (45%), Positives = 61/99 (61%), Gaps = 11/99 (11%)

Query: 100 GSYLLDS---ENTSGA-LPRLPQTPKQPQ-------KRSRAAFSHTQVIELERKFSHQKY 148
           G++ LD     +T+G  LP++P    Q Q       +R R AF+  Q++ELE +F   KY
Sbjct: 206 GTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKY 265

Query: 149 LSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSE 187
           LS P+R  +A +L LTETQVKIWFQNRR K KR + + E
Sbjct: 266 LSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKE 304


>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
          Length = 348

 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 57/146 (39%), Positives = 74/146 (50%), Gaps = 19/146 (13%)

Query: 38  GAQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEE--AETLAETEP 95
           GA R  G+  S+ + DP+ + E       S     +D   TG  A  EE     L ET P
Sbjct: 176 GAVRGQGKDESKVEDDPKGKEESFSL--ESDVDYSSDDNLTGQAAHKEEDPGHALEETPP 233

Query: 96  ERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERA 155
                        +SGA      T K   +R R AF+  Q++ELE++F  +KYLS  ER+
Sbjct: 234 -------------SSGAAGSTTSTGKN--RRRRTAFTSEQLLELEKEFHCKKYLSLTERS 278

Query: 156 HLAKNLKLTETQVKIWFQNRRYKTKR 181
            +A  LKL+E QVKIWFQNRR K KR
Sbjct: 279 QIAHALKLSEVQVKIWFQNRRAKWKR 304


>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 653

 Score = 75.9 bits (185), Expect = 3e-14
 Identities = 52/139 (37%), Positives = 70/139 (50%), Gaps = 29/139 (20%)

Query: 48  SQRQRDPEPEPE----PEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYL 103
           S RQR P P       P P GG +  G        G    P+   T A+ + +R      
Sbjct: 42  STRQRPPGPRENSPVAPGPPGGAAAPG--------GAGTTPQGTATAAKPKRKR------ 87

Query: 104 LDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKL 163
             S++ SG             +R+R AF++ Q++ LE KF   +YLS  ER +LA +L L
Sbjct: 88  TGSDSKSGK-----------PRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSL 136

Query: 164 TETQVKIWFQNRRYKTKRK 182
           TETQVKIWFQNRR K K++
Sbjct: 137 TETQVKIWFQNRRTKWKKQ 155


>gi|24497513 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 55/180 (30%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 54  PEPEPEPEPEGGRSRAGAQNDQLSTGPRAAP-----EEAETLAETEPERHLGSYLLDSEN 108
           P P   P P        A N+        +P       A+ +     E    +    S +
Sbjct: 114 PTPAAPPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSS 173

Query: 109 TSGALPRLPQTP--KQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTET 166
           +SG      ++P  +   KR+R A++  Q++ELE++F   +YL  P R  +A  L LTE 
Sbjct: 174 SSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTER 233

Query: 167 QVKIWFQNRRYKTKRKQ-----LSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYP 221
           Q+KIWFQNRR K K+ Q     L+S  G     S +P       +  S+ S+ NS PY P
Sbjct: 234 QIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLN--SMHSLVNSVPYEP 291


>gi|13562112 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 55/180 (30%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 54  PEPEPEPEPEGGRSRAGAQNDQLSTGPRAAP-----EEAETLAETEPERHLGSYLLDSEN 108
           P P   P P        A N+        +P       A+ +     E    +    S +
Sbjct: 114 PTPAAPPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSS 173

Query: 109 TSGALPRLPQTP--KQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTET 166
           +SG      ++P  +   KR+R A++  Q++ELE++F   +YL  P R  +A  L LTE 
Sbjct: 174 SSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTER 233

Query: 167 QVKIWFQNRRYKTKRKQ-----LSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYP 221
           Q+KIWFQNRR K K+ Q     L+S  G     S +P       +  S+ S+ NS PY P
Sbjct: 234 QIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLN--SMHSLVNSVPYEP 291


>gi|157743259 H6 family homeobox 3 [Homo sapiens]
          Length = 357

 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 40/69 (57%), Positives = 51/69 (73%), Gaps = 1/69 (1%)

Query: 120 PKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKT 179
           P   +K++R  FS +QV +LE  F  ++YLS+ ERA LA +L LTETQVKIWFQNRR K 
Sbjct: 223 PACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKW 282

Query: 180 KRKQLSSEL 188
           KR QL++EL
Sbjct: 283 KR-QLAAEL 290


>gi|27886557 msh homeobox 2 [Homo sapiens]
          Length = 267

 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 74/240 (30%), Positives = 102/240 (42%), Gaps = 40/240 (16%)

Query: 4   VPEPRPGEAKAEGAAPPTPSKPLT-SFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPEP 62
           V  P PG   AEGAA     K  +  F ++ ++ D              + P  E  P P
Sbjct: 21  VAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSD--------------KKPPKEASPLP 66

Query: 63  EGGRSRAGAQNDQL----------STGPRAAPEEAETLAETEPERHLGSYLLDSENTSGA 112
               S        L          S GP   P E  ++     E   G+  +        
Sbjct: 67  AESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSED--GAAWMQEPGRYSP 124

Query: 113 LPR--LPQT----PKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTET 166
            PR   P T      +  ++ R  F+ +Q++ LERKF  ++YLS  ERA  + +L LTET
Sbjct: 125 PPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTET 184

Query: 167 QVKIWFQNRRYKTKRKQLSSELGDLEKHSS--LPALKEEAF---SRASLVSVYN-SYPYY 220
           QVKIWFQNRR K KR Q  +EL  L+  +   LP+     F   S     S+Y  SYP++
Sbjct: 185 QVKIWFQNRRAKAKRLQ-EAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASYPFH 243


>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
          Length = 330

 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 40/96 (41%), Positives = 63/96 (65%), Gaps = 2/96 (2%)

Query: 114 PRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQ 173
           P   +TP + +K+ R +F+  Q+ ELE++F  QKYL++ ERA LAK LK+T+ QVK WFQ
Sbjct: 192 PYQNRTPPK-KKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQ 250

Query: 174 NRRYKTKRKQLSSELGDLEK-HSSLPALKEEAFSRA 208
           NRR K +R+       + ++ +  L  L++EAF ++
Sbjct: 251 NRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKS 286


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,272,820
Number of Sequences: 37866
Number of extensions: 626577
Number of successful extensions: 4956
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 357
Number of HSP's successfully gapped in prelim test: 372
Number of HSP's that attempted gapping in prelim test: 3942
Number of HSP's gapped (non-prelim): 1227
length of query: 234
length of database: 18,247,518
effective HSP length: 99
effective length of query: 135
effective length of database: 14,498,784
effective search space: 1957335840
effective search space used: 1957335840
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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