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Search of human proteins with 19923202
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
(747 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 1563 0.0
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 984 0.0
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 933 0.0
gi|210032580 SET domain containing 1B [Homo sapiens] 102 2e-21
gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens] 101 3e-21
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 100 4e-21
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 100 8e-21
gi|55741677 SET domain containing 1A [Homo sapiens] 97 5e-20
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 97 7e-20
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 97 7e-20
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 97 7e-20
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 97 7e-20
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 97 7e-20
gi|19923586 nuclear receptor binding SET domain protein 1 isofor... 97 7e-20
gi|197313748 SET domain containing 2 [Homo sapiens] 96 9e-20
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens] 96 9e-20
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 96 2e-19
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 94 5e-19
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 94 6e-19
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 92 1e-18
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 89 1e-17
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 89 1e-17
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 88 3e-17
gi|194306650 SET domain and mariner transposase fusion [Homo sap... 81 3e-15
gi|45356743 SET domain-containing 8 [Homo sapiens] 65 2e-10
gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens] 52 3e-06
gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens] 52 3e-06
gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens] 50 1e-05
gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens] 50 1e-05
gi|18139549 SET domain-containing protein 7 [Homo sapiens] 41 0.004
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 1563 bits (4048), Expect = 0.0
Identities = 747/747 (100%), Positives = 747/747 (100%)
Query: 1 MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW 60
MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
Sbjct: 1 MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW 60
Query: 61 KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN 120
KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
Sbjct: 61 KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN 120
Query: 121 FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV 180
FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
Sbjct: 121 FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV 180
Query: 181 DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI 240
DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
Sbjct: 181 DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI 240
Query: 241 ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR 300
ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
Sbjct: 241 ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR 300
Query: 301 RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR 360
RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
Sbjct: 301 RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR 360
Query: 361 RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP 420
RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
Sbjct: 361 RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP 420
Query: 421 QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK 480
QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
Sbjct: 421 QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK 480
Query: 481 LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT 540
LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
Sbjct: 481 LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT 540
Query: 541 QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV 600
QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
Sbjct: 541 QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV 600
Query: 601 SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD 660
SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
Sbjct: 601 SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD 660
Query: 661 KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG 720
KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
Sbjct: 661 KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG 720
Query: 721 EELFFDYRYSQADALKYVGIERETDVL 747
EELFFDYRYSQADALKYVGIERETDVL
Sbjct: 721 EELFFDYRYSQADALKYVGIERETDVL 747
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 984 bits (2543), Expect = 0.0
Identities = 486/759 (64%), Positives = 579/759 (76%), Gaps = 50/759 (6%)
Query: 15 WKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQSMKPV 74
W+++VKSEYMRLRQLKR + K+++ +N K+ E+T+ILN+EWK+ R+QPV + V
Sbjct: 15 WRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSV 74
Query: 75 SGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPY 134
S ++C++ S F +Q + +++LN VA VPIMYSWSPLQQNFMVEDETVL NIPY
Sbjct: 75 SSLRGTRECSVTSDLD-FPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPY 133
Query: 135 MGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEEGH 194
MGDEV ++D TFIEELI NYDGKVHG+ E I+D +F+ELV+AL QY+D++++
Sbjct: 134 MGDEVLDQDGTFIEELIKNYDGKVHGDREC----GFINDEIFVELVNALGQYNDDDDDDD 189
Query: 195 NDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMK 254
D + +++ K DL R K + ++FP+D IF AI+SMFP+ G +++K
Sbjct: 190 GDDPEEREEKQK-DLEDHRDDK-------ESRPPRKFPSDKIFEAISSMFPDKGTAEELK 241
Query: 255 ERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLH---- 310
E+Y+ELTE P ALPP+CTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLH
Sbjct: 242 EKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHRKCN 301
Query: 311 -PFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAM------LHNPRSKCSGRRRR 363
FHATPN YKRKN E ++ +PCG C+ LEGAKE+A + P + GRRR
Sbjct: 302 YSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRG 361
Query: 364 RHHIVSASCSNASASAVAETKEGDSDRDTGN---------------DWASSSSEANSRCQ 408
R S+ S + + V E+K+ DSDR+ G D SSSSEANSRCQ
Sbjct: 362 RLPNNSSRPSTPTIN-VLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQ 420
Query: 409 TPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQV 468
TP K K + PP E VEW+GAE S+FRV GTY++NFC+IARL+GTKTC+QV
Sbjct: 421 TPIKMKPNIEPP---------ENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQV 471
Query: 469 FQFAVKES-LILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHP 527
++F VKES +I P +++ P +KKKRKHRLWAAHCRKIQLKKD SS VYNYQPCDHP
Sbjct: 472 YEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHP 531
Query: 528 DRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCL 587
+PCDS+CPC++ QNFCEKFCQC+ +CQNRFPGCRCK QCNTKQCPCYLAVRECDPDLCL
Sbjct: 532 RQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCL 591
Query: 588 TCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELI 647
TCGA++HWD K VSCKNCSIQRG KKHLLLAPSDVAGWG FIK+ VQKNEFISEYCGE+I
Sbjct: 592 TCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEII 651
Query: 648 SQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDH 707
SQDEADRRGKVYDKYM SFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKV+MVNGDH
Sbjct: 652 SQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDH 711
Query: 708 RIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDV 746
RIGIFAKRAIQ GEELFFDYRYSQADALKYVGIERE ++
Sbjct: 712 RIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEI 750
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 933 bits (2411), Expect = 0.0
Identities = 466/754 (61%), Positives = 551/754 (73%), Gaps = 84/754 (11%)
Query: 15 WKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQSMKPV 74
W+++VKSEYMRLRQLKR + K+++ +N K+ E+T+ILN+EWK+ R+QPV
Sbjct: 15 WRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVH----- 69
Query: 75 SGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPY 134
I+ S S L+ VEDETVL NIPY
Sbjct: 70 -----------------------------------ILTSVSSLRGTREVEDETVLHNIPY 94
Query: 135 MGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEEGH 194
MGDEV ++D TFIEELI NYDGKVHG+ E I+D +F+ELV+AL QY+D++++
Sbjct: 95 MGDEVLDQDGTFIEELIKNYDGKVHGDREC----GFINDEIFVELVNALGQYNDDDDDDD 150
Query: 195 NDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMK 254
D + +++ K DL R K + ++FP+D IF AI+SMFP+ G +++K
Sbjct: 151 GDDPEEREEKQK-DLEDHRDDK-------ESRPPRKFPSDKIFEAISSMFPDKGTAEELK 202
Query: 255 ERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHA 314
E+Y+ELTE P ALPP+CTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHA
Sbjct: 203 EKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHA 262
Query: 315 TPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAM------LHNPRSKCSGRRRRRHHIV 368
TPN YKRKN E ++ +PCG C+ LEGAKE+A + P + GRRR R
Sbjct: 263 TPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPNN 322
Query: 369 SASCSNASASAVAETKEGDSDRDTGN---------------DWASSSSEANSRCQTPTKQ 413
S+ S + + V E+K+ DSDR+ G D SSSSEANSRCQTP K
Sbjct: 323 SSRPSTPTIN-VLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKM 381
Query: 414 KASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAV 473
K + PP E VEW+GAE S+FRV GTY++NFC+IARL+GTKTC+QV++F V
Sbjct: 382 KPNIEPP---------ENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRV 432
Query: 474 KES-LILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCD 532
KES +I P +++ P +KKKRKHRLWAAHCRKIQLKKD SS VYNYQPCDHP +PCD
Sbjct: 433 KESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCD 492
Query: 533 STCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGAS 592
S+CPC++ QNFCEKFCQC+ +CQNRFPGCRCK QCNTKQCPCYLAVRECDPDLCLTCGA+
Sbjct: 493 SSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAA 552
Query: 593 EHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEA 652
+HWD K VSCKNCSIQRG KKHLLLAPSDVAGWG FIK+ VQKNEFISEYCGE+ISQDEA
Sbjct: 553 DHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEA 612
Query: 653 DRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIF 712
DRRGKVYDKYM SFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKV+MVNGDHRIGIF
Sbjct: 613 DRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIF 672
Query: 713 AKRAIQAGEELFFDYRYSQADALKYVGIERETDV 746
AKRAIQ GEELFFDYRYSQADALKYVGIERE ++
Sbjct: 673 AKRAIQTGEELFFDYRYSQADALKYVGIEREMEI 706
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 102 bits (253), Expect = 2e-21
Identities = 51/124 (41%), Positives = 74/124 (59%), Gaps = 2/124 (1%)
Query: 612 KKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDK--YMSSFLFN 669
KK L S + WG F E + +E + EY G+ I Q AD R K Y+ SS++F
Sbjct: 1783 KKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFR 1842
Query: 670 LNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRY 729
+++D ++DAT+ GN RF NHS NPNCYAKV+ V +I I++K+ I EE+ +DY++
Sbjct: 1843 VDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKF 1902
Query: 730 SQAD 733
D
Sbjct: 1903 PIED 1906
>gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]
Length = 412
Score = 101 bits (251), Expect = 3e-21
Identities = 56/134 (41%), Positives = 81/134 (60%), Gaps = 8/134 (5%)
Query: 602 CKNCSIQRGLKKHL-LLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD 660
C N +Q+G++ L + D GWG E ++KN F+ EY GE+I+ +EA+RRG++YD
Sbjct: 232 CPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYD 291
Query: 661 KYMSSFLFNLN---NDFVVDATRKGNKIRFANHSVNPNCYAKVVMV-NGDH---RIGIFA 713
+ +++LF+L+ + + VDA GN F NHS +PN V + N D RI FA
Sbjct: 292 RQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFA 351
Query: 714 KRAIQAGEELFFDY 727
R I+AGEEL FDY
Sbjct: 352 TRTIRAGEELTFDY 365
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 100 bits (250), Expect = 4e-21
Identities = 49/116 (42%), Positives = 70/116 (60%), Gaps = 1/116 (0%)
Query: 620 SDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD-KYMSSFLFNLNNDFVVDA 678
S + G G F K ++ E + EY G +I + D+R K YD K + ++F +++ VVDA
Sbjct: 3836 SPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDA 3895
Query: 679 TRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADA 734
T GN RF NHS PNCY++V+ ++G I IFA R I GEEL +DY++ DA
Sbjct: 3896 TMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDA 3951
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 99.8 bits (247), Expect = 8e-21
Identities = 62/182 (34%), Positives = 94/182 (51%), Gaps = 20/182 (10%)
Query: 548 CQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSI 607
C C P +N C +++C + + EC P +C A + C+N
Sbjct: 1098 CNCKPADENP---CGLESECLNR-----MLQYECHPQVC---PAGDR-------CQNQCF 1139
Query: 608 QRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGK-VYDKYMSSF 666
+ L + ++ GWG K S++K EF++EY GELI ++E R K ++ +++F
Sbjct: 1140 TKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNF 1199
Query: 667 -LFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFF 725
+ + D ++DA KGN RF NHS NPNC + VNGD R+G+FA I AG EL F
Sbjct: 1200 YMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTF 1259
Query: 726 DY 727
+Y
Sbjct: 1260 NY 1261
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 97.1 bits (240), Expect = 5e-20
Identities = 49/124 (39%), Positives = 72/124 (58%), Gaps = 2/124 (1%)
Query: 612 KKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVY--DKYMSSFLFN 669
KK L S + WG F E + +E + EY G+ I Q AD R K Y + SS+LF
Sbjct: 1567 KKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFR 1626
Query: 670 LNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRY 729
+++D ++DAT+ GN RF NH PNCYAKV+ + +I I++K+ I EE+ +DY++
Sbjct: 1627 VDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKF 1686
Query: 730 SQAD 733
D
Sbjct: 1687 PLED 1690
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 96.7 bits (239), Expect = 7e-20
Identities = 62/182 (34%), Positives = 89/182 (48%), Gaps = 23/182 (12%)
Query: 556 NRFPGCRCKTQCNTKQCPC--------YLAVRECDPDLCLTCGASEHWDCKVVSCKNCSI 607
+ P C CK T + PC + + EC P +C A E C+N
Sbjct: 1011 SEIPKCNCKP---TDENPCGFDSECLNRMLMFECHPQVC---PAGEF-------CQNQCF 1057
Query: 608 QRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGK-VYDKYMSSF 666
+ + +D GWG K ++K EF++EY GELI ++E R K ++ ++ F
Sbjct: 1058 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 1117
Query: 667 -LFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFF 725
+ ++ D ++DA KGN RF NHS PNC VNGD R+G+FA I AG EL F
Sbjct: 1118 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 1177
Query: 726 DY 727
+Y
Sbjct: 1178 NY 1179
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 96.7 bits (239), Expect = 7e-20
Identities = 62/182 (34%), Positives = 89/182 (48%), Gaps = 23/182 (12%)
Query: 556 NRFPGCRCKTQCNTKQCPC--------YLAVRECDPDLCLTCGASEHWDCKVVSCKNCSI 607
+ P C CK T + PC + + EC P +C A E C+N
Sbjct: 1011 SEIPKCNCKP---TDENPCGFDSECLNRMLMFECHPQVC---PAGEF-------CQNQCF 1057
Query: 608 QRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGK-VYDKYMSSF 666
+ + +D GWG K ++K EF++EY GELI ++E R K ++ ++ F
Sbjct: 1058 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 1117
Query: 667 -LFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFF 725
+ ++ D ++DA KGN RF NHS PNC VNGD R+G+FA I AG EL F
Sbjct: 1118 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 1177
Query: 726 DY 727
+Y
Sbjct: 1178 NY 1179
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 96.7 bits (239), Expect = 7e-20
Identities = 62/182 (34%), Positives = 89/182 (48%), Gaps = 23/182 (12%)
Query: 556 NRFPGCRCKTQCNTKQCPC--------YLAVRECDPDLCLTCGASEHWDCKVVSCKNCSI 607
+ P C CK T + PC + + EC P +C A E C+N
Sbjct: 1011 SEIPKCNCKP---TDENPCGFDSECLNRMLMFECHPQVC---PAGEF-------CQNQCF 1057
Query: 608 QRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGK-VYDKYMSSF 666
+ + +D GWG K ++K EF++EY GELI ++E R K ++ ++ F
Sbjct: 1058 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 1117
Query: 667 -LFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFF 725
+ ++ D ++DA KGN RF NHS PNC VNGD R+G+FA I AG EL F
Sbjct: 1118 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 1177
Query: 726 DY 727
+Y
Sbjct: 1178 NY 1179
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 96.7 bits (239), Expect = 7e-20
Identities = 62/182 (34%), Positives = 89/182 (48%), Gaps = 23/182 (12%)
Query: 556 NRFPGCRCKTQCNTKQCPC--------YLAVRECDPDLCLTCGASEHWDCKVVSCKNCSI 607
+ P C CK T + PC + + EC P +C A E C+N
Sbjct: 1011 SEIPKCNCKP---TDENPCGFDSECLNRMLMFECHPQVC---PAGEF-------CQNQCF 1057
Query: 608 QRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGK-VYDKYMSSF 666
+ + +D GWG K ++K EF++EY GELI ++E R K ++ ++ F
Sbjct: 1058 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 1117
Query: 667 -LFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFF 725
+ ++ D ++DA KGN RF NHS PNC VNGD R+G+FA I AG EL F
Sbjct: 1118 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 1177
Query: 726 DY 727
+Y
Sbjct: 1178 NY 1179
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 96.7 bits (239), Expect = 7e-20
Identities = 59/182 (32%), Positives = 88/182 (48%), Gaps = 23/182 (12%)
Query: 556 NRFPGCRCKTQCNTKQCPC--------YLAVRECDPDLCLTCGASEHWDCKVVSCKNCSI 607
+ P C CK T + PC + + EC P +C G ++ I
Sbjct: 1621 SEIPRCNCKA---TDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPEVEI 1677
Query: 608 QRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKY--MSS 665
R L++ GWG K ++K EF++EY GELI ++E R + ++ +
Sbjct: 1678 FRTLQR----------GWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNF 1727
Query: 666 FLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFF 725
++ L+ D ++DA KGN RF NH PNC + VNGD R+G+FA I+AG EL F
Sbjct: 1728 YMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTF 1787
Query: 726 DY 727
+Y
Sbjct: 1788 NY 1789
>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
[Homo sapiens]
Length = 2696
Score = 96.7 bits (239), Expect = 7e-20
Identities = 59/182 (32%), Positives = 88/182 (48%), Gaps = 23/182 (12%)
Query: 556 NRFPGCRCKTQCNTKQCPC--------YLAVRECDPDLCLTCGASEHWDCKVVSCKNCSI 607
+ P C CK T + PC + + EC P +C G ++ I
Sbjct: 1890 SEIPRCNCKA---TDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPEVEI 1946
Query: 608 QRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKY--MSS 665
R L++ GWG K ++K EF++EY GELI ++E R + ++ +
Sbjct: 1947 FRTLQR----------GWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNF 1996
Query: 666 FLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFF 725
++ L+ D ++DA KGN RF NH PNC + VNGD R+G+FA I+AG EL F
Sbjct: 1997 YMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTF 2056
Query: 726 DY 727
+Y
Sbjct: 2057 NY 2058
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 96.3 bits (238), Expect = 9e-20
Identities = 48/132 (36%), Positives = 71/132 (53%), Gaps = 2/132 (1%)
Query: 602 CKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVY-- 659
C N QR + + ++ GWG + + N F+ EYCGE++ E R K Y
Sbjct: 1539 CSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYAR 1598
Query: 660 DKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQA 719
+K + + L ND ++DAT+KGN RF NHS PNC + VNG R+G F + + +
Sbjct: 1599 NKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPS 1658
Query: 720 GEELFFDYRYSQ 731
G EL FDY++ +
Sbjct: 1659 GSELTFDYQFQR 1670
>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
Length = 350
Score = 96.3 bits (238), Expect = 9e-20
Identities = 79/272 (29%), Positives = 126/272 (46%), Gaps = 47/272 (17%)
Query: 474 KESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYN-YQPCDHPDRPCD 532
K+ + L+ DEL +++K K ++ + + L+ S N Y+P +
Sbjct: 72 KQRIALQRWQDEL---NRRKNHKGMIFVENT--VDLEGPPSDFYYINEYKPAPGISLVNE 126
Query: 533 STCPCIMTQNFCEKFCQC--------NPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPD 584
+T C T F +K C N + Q + P +CN++ C +C PD
Sbjct: 127 ATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSR---C-----QCGPD 178
Query: 585 LCLTCGASEHWDCKVVSCKNCSIQRGLKKHL-LLAPSDVAGWGTFIKESVQKNEFISEYC 643
C N +Q+G + L + S+ GWG +++ F+ EY
Sbjct: 179 -----------------CPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYV 221
Query: 644 GELISQDEADRRGKVYDKYMSSFLFNL---NNDFVVDATRKGNKIRFANHSVNPNCYAKV 700
GE+I+ +EA+RRG+ YD ++LF+L +++F VDA R GN F NHS +PN
Sbjct: 222 GEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFN 281
Query: 701 VMVNGDH----RIGIFAKRAIQAGEELFFDYR 728
V ++ RI +F+ R I AGEEL FDY+
Sbjct: 282 VFIDNLDTRLPRIALFSTRTINAGEELTFDYQ 313
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 95.5 bits (236), Expect = 2e-19
Identities = 60/184 (32%), Positives = 89/184 (48%), Gaps = 19/184 (10%)
Query: 548 CQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSI 607
C C + GC C + EC P+ C CG C N I
Sbjct: 2091 CNCKKPDDDTRKGC-------VDDCLNRMIFAECSPNTC-PCGEQ---------CCNQRI 2133
Query: 608 QRGLKKHLLLA-PSDVAGWGTFIKESVQKNEFISEYCGELISQDE-ADRRGKVYDKYMSS 665
QR L ++ GWG KE ++ +FI EY GE++S+ E +R + Y +
Sbjct: 2134 QRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDH 2193
Query: 666 FLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFF 725
+ NL++ V+D+ R GN+ RF NHS +PNC + VNG +RIG++A + + AG EL +
Sbjct: 2194 YCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTY 2253
Query: 726 DYRY 729
DY +
Sbjct: 2254 DYNF 2257
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 94.0 bits (232), Expect = 5e-19
Identities = 46/123 (37%), Positives = 72/123 (58%), Gaps = 1/123 (0%)
Query: 612 KKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSS-FLFNL 670
K ++ LA S + G G + ++K+ + EY G +I + A+R+ K+Y+ ++F +
Sbjct: 4770 KSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRM 4829
Query: 671 NNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYS 730
+ND V+DAT G R+ NHS PNC A+VV H+I I + R IQ GEEL +DY++
Sbjct: 4830 DNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKFD 4889
Query: 731 QAD 733
D
Sbjct: 4890 FED 4892
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 93.6 bits (231), Expect = 6e-19
Identities = 49/116 (42%), Positives = 68/116 (58%), Gaps = 1/116 (0%)
Query: 620 SDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD-KYMSSFLFNLNNDFVVDA 678
S + G G F K ++ E + EY G +I D+R K YD K + ++F +++ VVDA
Sbjct: 2582 SAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDA 2641
Query: 679 TRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADA 734
T GN RF NHS PNC+++V+ V G I IFA R I GEEL +DY++ DA
Sbjct: 2642 TMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDA 2697
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 92.4 bits (228), Expect = 1e-18
Identities = 45/123 (36%), Positives = 74/123 (60%), Gaps = 1/123 (0%)
Query: 612 KKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSS-FLFNL 670
K ++ LA S + G G + + ++K+ + EY G +I + A+RR K+Y++ ++F +
Sbjct: 5396 KNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRI 5455
Query: 671 NNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYS 730
NN+ V+DAT G R+ NHS PNC A+VV + + +I I + R I GEEL +DY++
Sbjct: 5456 NNEHVIDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFD 5515
Query: 731 QAD 733
D
Sbjct: 5516 FED 5518
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2 isoform
b [Homo sapiens]
Length = 1176
Score = 89.0 bits (219), Expect = 1e-17
Identities = 66/191 (34%), Positives = 91/191 (47%), Gaps = 34/191 (17%)
Query: 561 CRCKTQCNTKQCPC-YLAVR--------------ECDPDLCLTCG-ASEHWDCKVVSCKN 604
C C C++ C C L++R + +P L C A W +CKN
Sbjct: 940 CTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWR----NCKN 995
Query: 605 CSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMS 664
+Q G+K L L + GWG +++ + FI EY GELIS EAD R
Sbjct: 996 RVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVRED------D 1049
Query: 665 SFLFNLNND----FVVDATRKGNKIRFANHSVNPNCY-AKVVMVNGD---HRIGIFAKRA 716
S+LF+L+N + +DA GN RF NH +PN +V M++ D RI F+ R
Sbjct: 1050 SYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRD 1109
Query: 717 IQAGEELFFDY 727
I+ GEEL FDY
Sbjct: 1110 IRTGEELGFDY 1120
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2 isoform
a [Homo sapiens]
Length = 1210
Score = 89.0 bits (219), Expect = 1e-17
Identities = 66/191 (34%), Positives = 91/191 (47%), Gaps = 34/191 (17%)
Query: 561 CRCKTQCNTKQCPC-YLAVR--------------ECDPDLCLTCG-ASEHWDCKVVSCKN 604
C C C++ C C L++R + +P L C A W +CKN
Sbjct: 974 CTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWR----NCKN 1029
Query: 605 CSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMS 664
+Q G+K L L + GWG +++ + FI EY GELIS EAD R
Sbjct: 1030 RVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVRED------D 1083
Query: 665 SFLFNLNND----FVVDATRKGNKIRFANHSVNPNCY-AKVVMVNGD---HRIGIFAKRA 716
S+LF+L+N + +DA GN RF NH +PN +V M++ D RI F+ R
Sbjct: 1084 SYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRD 1143
Query: 717 IQAGEELFFDY 727
I+ GEEL FDY
Sbjct: 1144 IRTGEELGFDY 1154
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1 isoform
1 [Homo sapiens]
Length = 1298
Score = 87.8 bits (216), Expect = 3e-17
Identities = 68/220 (30%), Positives = 94/220 (42%), Gaps = 38/220 (17%)
Query: 536 PCIMTQNFCEKFCQCNPDCQNR----FPGCRCKTQCNTKQCPCYLAVREC---------- 581
PC + + C +P +R C C C++ C C C
Sbjct: 1033 PCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGRLLP 1092
Query: 582 -----DPDLCLTCG-ASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQK 635
+P L C A W +C+N +Q GL+ L L + GWG + +
Sbjct: 1093 EFNMAEPPLIFECNHACSCWR----NCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPP 1148
Query: 636 NEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNND----FVVDATRKGNKIRFANHS 691
F+ EY GELIS EAD R + S+LF+L+N + +DA GN RF NH
Sbjct: 1149 GTFVCEYVGELISDSEADVREE------DSYLFDLDNKDGEVYCIDARFYGNVSRFINHH 1202
Query: 692 VNPNCY-AKVVMVNGD---HRIGIFAKRAIQAGEELFFDY 727
PN +V M + D RI F+ R I+AGE+L FDY
Sbjct: 1203 CEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDY 1242
>gi|194306650 SET domain and mariner transposase fusion [Homo
sapiens]
Length = 684
Score = 81.3 bits (199), Expect = 3e-15
Identities = 59/194 (30%), Positives = 86/194 (44%), Gaps = 21/194 (10%)
Query: 555 QNRFPGCRC-KTQCNTKQCPCYLAVRECDPDLCLTC------GASEHWDCKVVS-----C 602
Q FPGC C KT C C C D + CL A ++C V+ C
Sbjct: 69 QITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNVLCRCSDHC 128
Query: 603 KNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKY 662
+N +Q+GL+ H + + GWG E + K F+ EY GE++ E RR + K
Sbjct: 129 RNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKS 188
Query: 663 MSSFLFNLNN--------DFVVDATRKGNKIRFANHSVNPNCYAKVVMVNG-DHRIGIFA 713
S+++ + + VD T GN RF NHS PN V ++ ++ +FA
Sbjct: 189 DSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFA 248
Query: 714 KRAIQAGEELFFDY 727
+ I EEL +DY
Sbjct: 249 AKDIVPEEELSYDY 262
>gi|45356743 SET domain-containing 8 [Homo sapiens]
Length = 352
Score = 65.5 bits (158), Expect = 2e-10
Identities = 42/128 (32%), Positives = 68/128 (53%), Gaps = 8/128 (6%)
Query: 607 IQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDK----- 661
I+ G ++ + + D G G + + +F+ EY G+LI +A +R +Y +
Sbjct: 210 IESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTG 269
Query: 662 -YMSSFLFNLNNDFVVDATRKGNKI-RFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQA 719
YM F + L+ + VDATR+ N++ R NHS NC K+ ++G + + A R I A
Sbjct: 270 CYMYYFQY-LSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAA 328
Query: 720 GEELFFDY 727
GEEL +DY
Sbjct: 329 GEELLYDY 336
>gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens]
Length = 1290
Score = 51.6 bits (122), Expect = 3e-06
Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 23/129 (17%)
Query: 560 GCRCKTQCNTK-QCPCY---LAVRECDP---------------DLCLTCGASE---HWDC 597
GC CK C K +C C+ + C P + CL G E C
Sbjct: 728 GCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKC 787
Query: 598 KVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRG- 656
C N +Q GL+ L L + GWG + + K F+ Y G++++ D AD+ G
Sbjct: 788 DPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGL 847
Query: 657 KVYDKYMSS 665
++ D+Y ++
Sbjct: 848 EMGDEYFAN 856
Score = 41.2 bits (95), Expect = 0.004
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 5/60 (8%)
Query: 674 FVVDATRKGNKIRFANHSVNPNCYAKVVMVN-GDHR---IGIFAKRAIQAGEELFFDYRY 729
+++DA +GN R+ NHS +PN + + V V+ D R + FA + I+AG EL +DY Y
Sbjct: 1208 YIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASK-IRAGTELTWDYNY 1266
>gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens]
Length = 1291
Score = 51.6 bits (122), Expect = 3e-06
Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 23/129 (17%)
Query: 560 GCRCKTQCNTK-QCPCY---LAVRECDP---------------DLCLTCGASE---HWDC 597
GC CK C K +C C+ + C P + CL G E C
Sbjct: 728 GCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKC 787
Query: 598 KVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRG- 656
C N +Q GL+ L L + GWG + + K F+ Y G++++ D AD+ G
Sbjct: 788 DPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGL 847
Query: 657 KVYDKYMSS 665
++ D+Y ++
Sbjct: 848 EMGDEYFAN 856
Score = 45.4 bits (106), Expect = 2e-04
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 4/60 (6%)
Query: 674 FVVDATRKGNKIRFANHSVNPNCYAKVVMVN-GDHR---IGIFAKRAIQAGEELFFDYRY 729
+++DA +GN R+ NHS +PN + + V V+ D R + FA + I+AG EL +DY Y
Sbjct: 1208 YIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNY 1267
>gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens]
Length = 707
Score = 49.7 bits (117), Expect = 1e-05
Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 4/66 (6%)
Query: 668 FNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHR----IGIFAKRAIQAGEEL 723
FN N F++DAT++GN RF NHS PN + V V +R + F R ++A EL
Sbjct: 618 FNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTEL 677
Query: 724 FFDYRY 729
+DY Y
Sbjct: 678 TWDYGY 683
Score = 33.9 bits (76), Expect = 0.57
Identities = 14/58 (24%), Positives = 28/58 (48%)
Query: 597 CKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR 654
C C+N +Q G + L + ++ GWG + + + F+ Y G L+S+ ++
Sbjct: 339 CNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEK 396
>gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens]
Length = 719
Score = 49.7 bits (117), Expect = 1e-05
Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 4/66 (6%)
Query: 668 FNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHR----IGIFAKRAIQAGEEL 723
FN N F++DAT++GN RF NHS PN + V V +R + F R ++A EL
Sbjct: 630 FNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTEL 689
Query: 724 FFDYRY 729
+DY Y
Sbjct: 690 TWDYGY 695
Score = 33.9 bits (76), Expect = 0.57
Identities = 14/58 (24%), Positives = 28/58 (48%)
Query: 597 CKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR 654
C C+N +Q G + L + ++ GWG + + + F+ Y G L+S+ ++
Sbjct: 351 CNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEK 408
>gi|18139549 SET domain-containing protein 7 [Homo sapiens]
Length = 366
Score = 41.2 bits (95), Expect = 0.004
Identities = 37/119 (31%), Positives = 50/119 (42%), Gaps = 13/119 (10%)
Query: 623 AGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKG 682
AG G F K +V N +S Y G I+ E D R D ++ +L+ + V+D
Sbjct: 226 AGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSR----DWALNGNTLSLDEETVIDVPEPY 281
Query: 683 NKI--------RFANHSVNPNC-YAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQA 732
N + ANHS PNC Y V I RA++A EEL Y Y +
Sbjct: 282 NHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHS 340
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,402,215
Number of Sequences: 37866
Number of extensions: 1518530
Number of successful extensions: 6224
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 98
Number of HSP's that attempted gapping in prelim test: 5878
Number of HSP's gapped (non-prelim): 366
length of query: 747
length of database: 18,247,518
effective HSP length: 110
effective length of query: 637
effective length of database: 14,082,258
effective search space: 8970398346
effective search space used: 8970398346
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.