Guide to the Human Genome
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Search of human proteins with 19923100

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923100 eyes absent 1 isoform b [Homo sapiens]
         (592 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923100 eyes absent 1 isoform b [Homo sapiens]                   1205   0.0  
gi|26667216 eyes absent 1 isoform b [Homo sapiens]                   1205   0.0  
gi|26667222 eyes absent 1 isoform a [Homo sapiens]                   1122   0.0  
gi|26667219 eyes absent 1 isoform c [Homo sapiens]                   1112   0.0  
gi|98991763 eyes absent 4 isoform b [Homo sapiens]                    847   0.0  
gi|98991760 eyes absent 4 isoform a [Homo sapiens]                    838   0.0  
gi|26667257 eyes absent 4 isoform d [Homo sapiens]                    822   0.0  
gi|26667227 eyes absent 2 isoform a [Homo sapiens]                    684   0.0  
gi|26667240 eyes absent 2 isoform b [Homo sapiens]                    684   0.0  
gi|26667235 eyes absent 2 isoform a [Homo sapiens]                    684   0.0  
gi|26667232 eyes absent 2 isoform a [Homo sapiens]                    684   0.0  
gi|26667230 eyes absent 2 isoform c [Homo sapiens]                    644   0.0  
gi|26667243 eyes absent 3 [Homo sapiens]                              548   e-156
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s...    60   6e-09
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s...    55   2e-07
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...    55   2e-07
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap...    55   2e-07
gi|161019170 mucin 5AC [Homo sapiens]                                  54   4e-07
gi|5454064 RNA binding motif protein 14 [Homo sapiens]                 54   4e-07
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...    53   7e-07
gi|55750053 atrophin-1 [Homo sapiens]                                  51   3e-06
gi|55750041 atrophin-1 [Homo sapiens]                                  51   3e-06
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             50   4e-06
gi|161016767 mucin 21 [Homo sapiens]                                   50   4e-06
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          50   8e-06
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    49   1e-05
gi|167736355 mucin 4 isoform a [Homo sapiens]                          49   1e-05
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    49   2e-05
gi|91982772 mucin 17 [Homo sapiens]                                    47   5e-05
gi|151301154 mucin 6, gastric [Homo sapiens]                           47   6e-05

>gi|19923100 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score = 1205 bits (3117), Expect = 0.0
 Identities = 592/592 (100%), Positives = 592/592 (100%)

Query: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS 60
           MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS
Sbjct: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS 60

Query: 61  LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ 120
           LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ
Sbjct: 61  LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ 120

Query: 121 ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY 180
           ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY
Sbjct: 121 ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY 180

Query: 181 SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM 240
           SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM
Sbjct: 181 SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM 240

Query: 241 TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD 300
           TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD
Sbjct: 241 TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD 300

Query: 301 GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGL 360
           GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGL
Sbjct: 301 GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGL 360

Query: 361 RMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL 420
           RMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL
Sbjct: 361 RMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL 420

Query: 421 ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT 480
           ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT
Sbjct: 421 ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT 480

Query: 481 LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER 540
           LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER
Sbjct: 481 LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER 540

Query: 541 IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 592
           IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL
Sbjct: 541 IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 592


>gi|26667216 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score = 1205 bits (3117), Expect = 0.0
 Identities = 592/592 (100%), Positives = 592/592 (100%)

Query: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS 60
           MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS
Sbjct: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS 60

Query: 61  LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ 120
           LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ
Sbjct: 61  LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ 120

Query: 121 ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY 180
           ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY
Sbjct: 121 ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY 180

Query: 181 SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM 240
           SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM
Sbjct: 181 SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM 240

Query: 241 TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD 300
           TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD
Sbjct: 241 TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD 300

Query: 301 GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGL 360
           GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGL
Sbjct: 301 GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGL 360

Query: 361 RMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL 420
           RMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL
Sbjct: 361 RMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL 420

Query: 421 ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT 480
           ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT
Sbjct: 421 ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT 480

Query: 481 LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER 540
           LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER
Sbjct: 481 LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER 540

Query: 541 IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 592
           IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL
Sbjct: 541 IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 592


>gi|26667222 eyes absent 1 isoform a [Homo sapiens]
          Length = 559

 Score = 1122 bits (2903), Expect = 0.0
 Identities = 551/551 (100%), Positives = 551/551 (100%)

Query: 42  VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP 101
           VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP
Sbjct: 9   VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP 68

Query: 102 SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT 161
           SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT
Sbjct: 69  SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT 128

Query: 162 GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF 221
           GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF
Sbjct: 129 GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF 188

Query: 222 GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH 281
           GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH
Sbjct: 189 GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH 248

Query: 282 SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT 341
           SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT
Sbjct: 249 SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT 308

Query: 342 GSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLST 401
           GSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLST
Sbjct: 309 GSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLST 368

Query: 402 YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR 461
           YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR
Sbjct: 369 YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR 428

Query: 462 EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF 521
           EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF
Sbjct: 429 EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF 488

Query: 522 PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM 581
           PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM
Sbjct: 489 PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM 548

Query: 582 ALHHALELEYL 592
           ALHHALELEYL
Sbjct: 549 ALHHALELEYL 559


>gi|26667219 eyes absent 1 isoform c [Homo sapiens]
          Length = 557

 Score = 1112 bits (2875), Expect = 0.0
 Identities = 557/592 (94%), Positives = 557/592 (94%), Gaps = 35/592 (5%)

Query: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS 60
           MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS
Sbjct: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGS 60

Query: 61  LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ 120
           LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ
Sbjct: 61  LNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQ 120

Query: 121 ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY 180
           ATAYATYPQPGQPYGISSYG     IKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY
Sbjct: 121 ATAYATYPQPGQPYGISSYG-----IKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY 175

Query: 181 SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM 240
           SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM
Sbjct: 176 SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM 235

Query: 241 TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD 300
           TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD
Sbjct: 236 TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD 295

Query: 301 GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGL 360
           GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGR          
Sbjct: 296 GKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGR---------- 345

Query: 361 RMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL 420
                               ECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL
Sbjct: 346 --------------------ECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCL 385

Query: 421 ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT 480
           ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT
Sbjct: 386 ATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLT 445

Query: 481 LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER 540
           LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER
Sbjct: 446 LALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFER 505

Query: 541 IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 592
           IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL
Sbjct: 506 IIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 557


>gi|98991763 eyes absent 4 isoform b [Homo sapiens]
          Length = 616

 Score =  847 bits (2189), Expect = 0.0
 Identities = 436/600 (72%), Positives = 497/600 (82%), Gaps = 21/600 (3%)

Query: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGT-----EVKTEPMSSSETAST 55
           MEMQDL SPH+ L G  ++P   KL  S+++S S+T NGT      VKTEP++SSET +T
Sbjct: 30  MEMQDLASPHT-LVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTAT 88

Query: 56  TADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAY-GQTQF 114
           T DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +PYPHIL TP++QTM+AY GQTQ+
Sbjct: 89  TGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-KPYPHILSTPAAQTMSAYAGQTQY 146

Query: 115 TTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTEGGLSQSQSPGQTGFLSYGTSFST 172
           + GMQQ   Y  Y Q GQPY + +Y  G +   IKTE GLSQ+QSP Q+G LSY   FST
Sbjct: 147 S-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFST 205

Query: 173 PQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNS 232
           PQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+ SQQDYPSY +FGQ QYAQYY++
Sbjct: 206 PQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 264

Query: 233 SPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDS 292
           S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q       E+ T+ SPSTPIKD D 
Sbjct: 265 STYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP-----GEFDTMQSPSTPIKDLD- 317

Query: 293 DRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDP 352
           +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDLDETIIVFHSLLTGSYA +YG+DP
Sbjct: 318 ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDP 376

Query: 353 PTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAA 412
           P +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTY+F TDGF AA
Sbjct: 377 PMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAA 436

Query: 413 ATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIE 472
           A+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYKNNVGGLLGPAKR+AWLQLRAEIE
Sbjct: 437 ASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIE 496

Query: 473 ALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKI 532
            LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPALAKVLLY LG  FPIENIYSATKI
Sbjct: 497 GLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKI 556

Query: 533 GKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 592
           GKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH MPFWRISSHSDL+ALH ALELEYL
Sbjct: 557 GKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616


>gi|98991760 eyes absent 4 isoform a [Homo sapiens]
          Length = 639

 Score =  838 bits (2166), Expect = 0.0
 Identities = 436/623 (69%), Positives = 497/623 (79%), Gaps = 44/623 (7%)

Query: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGT-------------------- 40
           MEMQDL SPH+ L G  ++P   KL  S+++S S+T NGT                    
Sbjct: 30  MEMQDLASPHT-LVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTP 88

Query: 41  --------EVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNR 92
                    VKTEP++SSET +TT DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +
Sbjct: 89  SSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-K 146

Query: 93  PYPHILPTPSSQTMAAY-GQTQFTTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTE 149
           PYPHIL TP++QTM+AY GQTQ++ GMQQ   Y  Y Q GQPY + +Y  G +   IKTE
Sbjct: 147 PYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTE 205

Query: 150 GGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFN 209
            GLSQ+QSP Q+G LSY   FSTPQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+
Sbjct: 206 SGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFS 264

Query: 210 SSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQA 269
            SQQDYPSY +FGQ QYAQYY++S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q 
Sbjct: 265 GSQQDYPSYTAFGQNQYAQYYSASTYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP 323

Query: 270 VTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDL 329
                 E+ T+ SPSTPIKD D +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDL
Sbjct: 324 -----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDL 376

Query: 330 DETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDD 389
           DETIIVFHSLLTGSYA +YG+DPP +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDD
Sbjct: 377 DETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDD 436

Query: 390 VSSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYK 449
           VSSDDNGQDLSTY+F TDGF AAA+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYK
Sbjct: 437 VSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYK 496

Query: 450 NNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPAL 509
           NNVGGLLGPAKR+AWLQLRAEIE LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPAL
Sbjct: 497 NNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPAL 556

Query: 510 AKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAM 569
           AKVLLY LG  FPIENIYSATKIGKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH M
Sbjct: 557 AKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNM 616

Query: 570 PFWRISSHSDLMALHHALELEYL 592
           PFWRISSHSDL+ALH ALELEYL
Sbjct: 617 PFWRISSHSDLLALHQALELEYL 639


>gi|26667257 eyes absent 4 isoform d [Homo sapiens]
          Length = 639

 Score =  822 bits (2123), Expect = 0.0
 Identities = 426/623 (68%), Positives = 490/623 (78%), Gaps = 44/623 (7%)

Query: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGT-------------------- 40
           MEMQDL SPH+ L G  ++P   KL  S+++S S+T NGT                    
Sbjct: 30  MEMQDLASPHT-LVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTP 88

Query: 41  --------EVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNR 92
                    VKTEP++SSET +TT DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +
Sbjct: 89  SSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-K 146

Query: 93  PYPHILPTPSSQTMAAY-GQTQFTTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTE 149
           PYPHIL TP++QTM+AY GQTQ++ GMQQ   Y  Y Q GQPY + +Y  G +   IKTE
Sbjct: 147 PYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTE 205

Query: 150 GGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFN 209
            GLSQ+QSP Q+G LSY   FSTPQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+
Sbjct: 206 SGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFS 264

Query: 210 SSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQA 269
            SQQDYPSY +FGQ QYAQYY++S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q 
Sbjct: 265 GSQQDYPSYTAFGQNQYAQYYSASTYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP 323

Query: 270 VTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDL 329
                 E+ T+ SPSTPIKD D +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDL
Sbjct: 324 -----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDL 376

Query: 330 DETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDD 389
           DETIIVFHSLLTGSYA +YG+DPP +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDD
Sbjct: 377 DETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDD 436

Query: 390 VSSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYK 449
           VSSDDNGQDLSTY+F TDGF AAA+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYK
Sbjct: 437 VSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYK 496

Query: 450 NNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPAL 509
           NNVGGLLGPAKR+AWLQLRAEIE LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPAL
Sbjct: 497 NNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPAL 556

Query: 510 AKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAM 569
           AKVLLY LG  FPIENIYSATKIGKESCFERI+ RFG  + YVVIGDG +EE  A +H M
Sbjct: 557 AKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAANQHNM 616

Query: 570 PFWRISSHSDLMALHHALELEYL 592
           PFWRISSHSDL+ALH ALELEYL
Sbjct: 617 PFWRISSHSDLLALHQALELEYL 639


>gi|26667227 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  684 bits (1765), Expect = 0.0
 Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)

Query: 91  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 150
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY      IKTE 
Sbjct: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105

Query: 151 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 210
            L+ S  PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158

Query: 211 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 270
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216

Query: 271 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 330
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276

Query: 331 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 390
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336

Query: 391 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 450
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396

Query: 451 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 510
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456

Query: 511 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 570
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516

Query: 571 FWRISSHSDLMALHHALELEYL 592
           FWRIS H+DL AL HALELEYL
Sbjct: 517 FWRISCHADLEALRHALELEYL 538


>gi|26667240 eyes absent 2 isoform b [Homo sapiens]
          Length = 543

 Score =  684 bits (1765), Expect = 0.0
 Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)

Query: 91  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 150
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY      IKTE 
Sbjct: 56  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 110

Query: 151 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 210
            L+ S  PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 111 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 163

Query: 211 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 270
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 164 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 221

Query: 271 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 330
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 222 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 281

Query: 331 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 390
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 282 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 341

Query: 391 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 450
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 342 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 401

Query: 451 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 510
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 402 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 461

Query: 511 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 570
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 462 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 521

Query: 571 FWRISSHSDLMALHHALELEYL 592
           FWRIS H+DL AL HALELEYL
Sbjct: 522 FWRISCHADLEALRHALELEYL 543


>gi|26667235 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  684 bits (1765), Expect = 0.0
 Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)

Query: 91  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 150
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY      IKTE 
Sbjct: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105

Query: 151 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 210
            L+ S  PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158

Query: 211 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 270
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216

Query: 271 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 330
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276

Query: 331 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 390
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336

Query: 391 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 450
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396

Query: 451 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 510
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456

Query: 511 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 570
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516

Query: 571 FWRISSHSDLMALHHALELEYL 592
           FWRIS H+DL AL HALELEYL
Sbjct: 517 FWRISCHADLEALRHALELEYL 538


>gi|26667232 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  684 bits (1765), Expect = 0.0
 Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)

Query: 91  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 150
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY      IKTE 
Sbjct: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105

Query: 151 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 210
            L+ S  PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158

Query: 211 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 270
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216

Query: 271 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 330
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276

Query: 331 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 390
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336

Query: 391 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 450
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396

Query: 451 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 510
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456

Query: 511 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 570
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516

Query: 571 FWRISSHSDLMALHHALELEYL 592
           FWRIS H+DL AL HALELEYL
Sbjct: 517 FWRISCHADLEALRHALELEYL 538


>gi|26667230 eyes absent 2 isoform c [Homo sapiens]
          Length = 514

 Score =  644 bits (1661), Expect = 0.0
 Identities = 323/502 (64%), Positives = 376/502 (74%), Gaps = 38/502 (7%)

Query: 91  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 150
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI S            
Sbjct: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS------------ 98

Query: 151 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 210
                              FST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 99  -------------------FSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 134

Query: 211 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 270
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 135 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 192

Query: 271 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 330
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 193 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 252

Query: 331 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 390
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 253 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 312

Query: 391 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 450
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 313 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 372

Query: 451 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 510
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 373 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 432

Query: 511 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 570
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 433 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 492

Query: 571 FWRISSHSDLMALHHALELEYL 592
           FWRIS H+DL AL HALELEYL
Sbjct: 493 FWRISCHADLEALRHALELEYL 514


>gi|26667243 eyes absent 3 [Homo sapiens]
          Length = 573

 Score =  548 bits (1413), Expect = e-156
 Identities = 296/557 (53%), Positives = 385/557 (69%), Gaps = 20/557 (3%)

Query: 44  TEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSS 103
           + P  S +   T++  S    S   +  + + PR ++ ++  Q+Y S +PY HIL  P S
Sbjct: 29  SNPDVSDQKPETSSLASNLPMSEEIMTCTDYIPRSSNDYTS-QMY-SAKPYAHILSVPVS 86

Query: 104 QTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGF 163
           +T A  GQTQ+ T +QQ   YA YPQ  Q YG+  +GALW G+K E GL Q+ SP Q   
Sbjct: 87  ET-AYPGQTQYQT-LQQTQPYAVYPQATQTYGLPPFGALWPGMKPESGLIQTPSPSQHSV 144

Query: 164 LSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTN---SSGFNSSQQDYPSYPS 220
           L+  T  +T QP  A YSY +Q SS  T++ + + ++++ N   ++  + S QDYP+Y  
Sbjct: 145 LTCTTGLTTSQPSPAHYSYPIQASS--TNASLISTSSTIANIPAAAVASISNQDYPTYTI 202

Query: 221 FGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVT-----DPTA 275
            GQ QY   Y SS +     T+S+   TT +   TYQ ++P     + A       DP+ 
Sbjct: 203 LGQNQYQACYPSSSFGVTGQTNSDAESTTLAAT-TYQSEKPSVMAPAPAAQRLSSGDPST 261

Query: 276 EYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIV 335
             S   S +TP KD+D D+ R+    K+RG+  R  + +   DS+LERVF+WDLDETII+
Sbjct: 262 SPSL--SQTTPSKDTD-DQSRKNMTSKNRGK--RKADATSSQDSELERVFLWDLDETIII 316

Query: 336 FHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDN 395
           FHSLLTGSYA +YG+DP   +  GL MEEMIF +ADTHLFFNDLEECDQVH++DV+SDDN
Sbjct: 317 FHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDLEECDQVHVEDVASDDN 376

Query: 396 GQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGL 455
           GQDLS Y+F TDGF  +  S +   + GV+GGVDWMRKLAFRYR+V+EIY+ +K+NVGGL
Sbjct: 377 GQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGGL 436

Query: 456 LGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLY 515
           L P ++EA  +LRAEIE LTDSWL  ALK+L LI SR NCVN+L+TTTQL+PALAKVLLY
Sbjct: 437 LSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVLITTTQLVPALAKVLLY 496

Query: 516 GLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRIS 575
           GLG +FPIENIYSATKIGKESCFERI+ RFG+KV YVVIGDG +EE  AK+H MPFWRI+
Sbjct: 497 GLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHNMPFWRIT 556

Query: 576 SHSDLMALHHALELEYL 592
           +H DL++LH ALEL++L
Sbjct: 557 NHGDLVSLHQALELDFL 573


>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
           sapiens]
          Length = 600

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 71/264 (26%), Positives = 98/264 (37%), Gaps = 29/264 (10%)

Query: 56  TADGSLNNFSGSAIGSSSFSPRPTHQFSPP-QIYPSNRPYPHILPTPSS----QTMAAYG 110
           + D S  + + +  G S+++ +PT  ++   Q Y       +  PT  S    QT A YG
Sbjct: 3   STDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62

Query: 111 QTQFTTGM-QQATAYAT------YPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGF 163
           QT + T   Q  T Y T      Y QP Q YG  +Y    A + T      +QS      
Sbjct: 63  QTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQS------ 116

Query: 164 LSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQ 223
            +YGT  + P  GQ P +      S T  +     + S  N+ G  SS   Y    S+GQ
Sbjct: 117 -AYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSS---YGQQSSYGQ 172

Query: 224 GQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSP 283
                 Y   P P  Y   + +    PS    Y  Q    G  S    D  +        
Sbjct: 173 ---QSSYGQQP-PTSYPPQTGSYSQAPS---QYSQQSSSYGQQSSFRQDHPSSMGVYGQE 225

Query: 284 STPIKDSDSDRLRRGSDGKSRGRG 307
           S        +R   G D + RGRG
Sbjct: 226 SGGFSGPGENRSMSGPDNRGRGRG 249


>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
           sapiens]
          Length = 354

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 70/283 (24%), Positives = 109/283 (38%), Gaps = 36/283 (12%)

Query: 56  TADGSLNNFSGSAIGSSSFSPRPTHQFSPP-QIYPSNRPYPHILPTPSS----QTMAAYG 110
           + D S  + + +  G S+++ +PT  ++   Q Y       +  PT  S    QT A YG
Sbjct: 3   STDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62

Query: 111 QTQFTTGM-QQATAYAT------YPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGF 163
           QT + T   Q  T Y T      Y QP Q YG  +Y    A + T      +QS      
Sbjct: 63  QTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQS------ 116

Query: 164 LSYGTSFSTPQPGQAPY----SYQMQGSSFTTSSGIYTGNNSLTNSS-GFNSSQQDYPSY 218
            +YGT  + P  GQ P     +    G+  T +S   +        S G+  S   YP  
Sbjct: 117 -AYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQV 175

Query: 219 PSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQE---PPSGITSQAVTDPTA 275
           P    G Y     ++P P++  TS +++  T    ++Y  Q     PS    Q+     +
Sbjct: 176 P----GSYPMQPVTAP-PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQS 230

Query: 276 EYS----TIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPS 314
            Y     T + P T        +  + S    +    R ++PS
Sbjct: 231 SYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPS 273


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
           sapiens]
          Length = 655

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 70/283 (24%), Positives = 109/283 (38%), Gaps = 36/283 (12%)

Query: 56  TADGSLNNFSGSAIGSSSFSPRPTHQFSPP-QIYPSNRPYPHILPTPSS----QTMAAYG 110
           + D S  + + +  G S+++ +PT  ++   Q Y       +  PT  S    QT A YG
Sbjct: 3   STDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62

Query: 111 QTQFTTGM-QQATAYAT------YPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGF 163
           QT + T   Q  T Y T      Y QP Q YG  +Y    A + T      +QS      
Sbjct: 63  QTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQS------ 116

Query: 164 LSYGTSFSTPQPGQAPY----SYQMQGSSFTTSSGIYTGNNSLTNSS-GFNSSQQDYPSY 218
            +YGT  + P  GQ P     +    G+  T +S   +        S G+  S   YP  
Sbjct: 117 -AYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQV 175

Query: 219 PSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQE---PPSGITSQAVTDPTA 275
           P    G Y     ++P P++  TS +++  T    ++Y  Q     PS    Q+     +
Sbjct: 176 P----GSYPMQPVTAP-PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQS 230

Query: 276 EYS----TIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPS 314
            Y     T + P T        +  + S    +    R ++PS
Sbjct: 231 SYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPS 273


>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
           sapiens]
          Length = 656

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 70/283 (24%), Positives = 109/283 (38%), Gaps = 36/283 (12%)

Query: 56  TADGSLNNFSGSAIGSSSFSPRPTHQFSPP-QIYPSNRPYPHILPTPSS----QTMAAYG 110
           + D S  + + +  G S+++ +PT  ++   Q Y       +  PT  S    QT A YG
Sbjct: 3   STDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62

Query: 111 QTQFTTGM-QQATAYAT------YPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGF 163
           QT + T   Q  T Y T      Y QP Q YG  +Y    A + T      +QS      
Sbjct: 63  QTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQS------ 116

Query: 164 LSYGTSFSTPQPGQAPY----SYQMQGSSFTTSSGIYTGNNSLTNSS-GFNSSQQDYPSY 218
            +YGT  + P  GQ P     +    G+  T +S   +        S G+  S   YP  
Sbjct: 117 -AYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQV 175

Query: 219 PSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQE---PPSGITSQAVTDPTA 275
           P    G Y     ++P P++  TS +++  T    ++Y  Q     PS    Q+     +
Sbjct: 176 P----GSYPMQPVTAP-PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQS 230

Query: 276 EYS----TIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPS 314
            Y     T + P T        +  + S    +    R ++PS
Sbjct: 231 SYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPS 273


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 75/299 (25%), Positives = 119/299 (39%), Gaps = 32/299 (10%)

Query: 14   SGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETA-------STTADGSLNNFSG 66
            S ++ S +    G  H+++ + TP  T  K  P SS  TA       ST    +  +F  
Sbjct: 4265 STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSF-- 4322

Query: 67   SAIGSSSFSPRPTH--QFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAY 124
            +AI SSS     T   Q + P    S         TPSS    A+  T  TT      A 
Sbjct: 4323 TAIPSSSLGTTWTRLSQTTTPTATMST-------ATPSSTPETAHTSTVLTTTATTTRAT 4375

Query: 125  ATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQ--------TGFLSYGTSFSTPQPG 176
             +   P    G +    +     T   ++ S SPG         +   +  TS ST  P 
Sbjct: 4376 GSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPS 4435

Query: 177  QAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYP 236
              P +        TT++ + TG+ +  +SS   S     P  P+     + +  + SP  
Sbjct: 4436 SVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGR--SLSPSS 4493

Query: 237  AHYMTSSNTSPTTPSTNATYQLQEPPSGIT-SQAVTDPTAEYST--IHSPSTPIKDSDS 292
             H + ++ TS T+  T  T  + EP +G + + A T  T ++ST  + SP    + ++S
Sbjct: 4494 PHTVRTAWTSATS-GTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTES 4551



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 74/299 (24%), Positives = 116/299 (38%), Gaps = 32/299 (10%)

Query: 14   SGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETA-------STTADGSLNNFSG 66
            S ++ S +    G  H+++ + TP  T  K  P SS  TA       ST    +  +F  
Sbjct: 3118 STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSF-- 3175

Query: 67   SAIGSSSFSPRPTH--QFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAY 124
            +AI SSS     T   Q + P    S         TPSS     +  T  TT      A 
Sbjct: 3176 TAIPSSSLGTTWTRLSQTTTPTATMST-------ATPSSTPETVHTSTVLTTTATTTGAT 3228

Query: 125  ATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFL--------SYGTSFSTPQPG 176
             +   P    G +    +     T    + S SPG    L        +  T  ST  P 
Sbjct: 3229 GSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPS 3288

Query: 177  QAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYP 236
              P +        TT++ + TG+ +  +SS   S     P  P+     + +  + SP  
Sbjct: 3289 SIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGR--SLSPSS 3346

Query: 237  AHYMTSSNTSPTTPSTNATYQLQEPPSGIT-SQAVTDPTAEYST--IHSPSTPIKDSDS 292
             H + ++ TS T+  T  T  + EP +G + + A T  T ++ST  + SP    + ++S
Sbjct: 3347 PHTVRTAWTSATS-GTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTES 3404



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 66/292 (22%), Positives = 107/292 (36%), Gaps = 32/292 (10%)

Query: 30   INSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYP 89
            + S + TP  T V   P SS  TA T    +    +  +  + S +P   H  +      
Sbjct: 3808 LRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTT 3867

Query: 90   SNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTE 149
            +       + TPSS    A+     TT +   T       P    G +    +W      
Sbjct: 3868 TTTRATGSVATPSSTPGTAH-----TTKVPTTTTTGFTATPSSSPGTALTPPVW------ 3916

Query: 150  GGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFN 209
              +S + +P   G        ST  P   P +        TT++ + TG+ +  +SS   
Sbjct: 3917 --ISTTTTPTTRG--------STVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQT 3966

Query: 210  SSQQDYPSYPSFGQGQYAQYY-NSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQ 268
            S     P  P+     + +    SSP+      +S TS    +T+ T      PS +TS 
Sbjct: 3967 SGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHIT-----EPSTVTSH 4021

Query: 269  --AVTDPTAEYST--IHSPSTPIKDSDS-DRLRRGSDGKSRGRGRRNNNPSP 315
              A T  T ++ST  + SP    + ++S       + G +RG  R     +P
Sbjct: 4022 TPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATP 4073



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 60/253 (23%), Positives = 94/253 (37%), Gaps = 60/253 (23%)

Query: 34   SMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRP 93
            S TP  T + TEP   S TA+ T     +  + S+  +++ +P  +   + P +  S   
Sbjct: 4914 SSTPGTTWILTEP---STTATVTVPTG-STATASSTQATAGTPHVSTTATTPTVTSSKAT 4969

Query: 94   YPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLS 153
                 P+ S  T  A    + T     AT++   P        SS G  W        LS
Sbjct: 4970 -----PSSSPGTATALPALRSTATTPTATSFTAIPS-------SSLGTTWTR------LS 5011

Query: 154  QSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQ 213
            Q+ +P  T  +S  T  STP+                 +S + T   + T ++G  ++  
Sbjct: 5012 QTTTP--TATMSTATPSSTPET--------------VHTSTVLTATATTTGATGSVATP- 5054

Query: 214  DYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDP 273
                             +S+P  AH    +   PTT +T  T      P    +   T P
Sbjct: 5055 -----------------SSTPGTAH----TTKVPTTTTTGFTATPSSSPGTALTPPTTTP 5093

Query: 274  TAEYSTIHSPSTP 286
             +  STIH+ STP
Sbjct: 5094 MSTMSTIHTSSTP 5106



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 72/284 (25%), Positives = 111/284 (39%), Gaps = 50/284 (17%)

Query: 17   SESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSP 76
            S  PS P    S   + S TP  T + T+P   + TA+TTA          + GS++   
Sbjct: 2576 SHCPSTP--ATSSTATPSSTPGTTWILTKP---TTTATTTA----------STGSTATPT 2620

Query: 77   RPTHQFSPPQIYPSNRPYPHIL---PTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQP 133
                   PP++  +    P +     TPSS    A       +     TA +  P P   
Sbjct: 2621 STLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPS-- 2678

Query: 134  YGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSS 193
               SS G  W        LSQ+ +P  T  +S  T  STP+   A  S  +  ++ TT +
Sbjct: 2679 ---SSLGTTWT------RLSQTTTP--TATMSTATPSSTPE--TAHTSTVLTATATTTGA 2725

Query: 194  GIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPA---HYMTSSNTSPTTP 250
               TG+ +  +S+   +     P+  + G   +    +SSP  A       S+ T+PTT 
Sbjct: 2726 ---TGSVATPSSTPGTAHTTKVPTTTTTG---FTATPSSSPGTALTPPVWISTTTTPTTR 2779

Query: 251  STNATYQLQEPPSGI--TSQAVTDPTAEYSTIHSPSTPIKDSDS 292
             +  T      PS I  T+   T  T   +T+ + S     S +
Sbjct: 2780 GSTVT------PSSIPGTTHTATVLTTTTTTVATGSMATPSSST 2817



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 69/295 (23%), Positives = 108/295 (36%), Gaps = 34/295 (11%)

Query: 14   SGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETA-------STTADGSLNNFSG 66
            S ++ S +    G  H+++ + TP  T  K  P SS  TA       ST    +  +F  
Sbjct: 4938 STATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSF-- 4995

Query: 67   SAIGSSSFSPRPTH--QFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAY 124
            +AI SSS     T   Q + P    S         TPSS     +  T  T       A 
Sbjct: 4996 TAIPSSSLGTTWTRLSQTTTPTATMST-------ATPSSTPETVHTSTVLTATATTTGAT 5048

Query: 125  ATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT---GFLSYGTSFSTPQPGQAPYS 181
             +   P    G +    +     T    + S SPG        +  ++ ST      P +
Sbjct: 5049 GSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPET 5108

Query: 182  YQMQGSSFTTSSGIYTGNNSLTNSSGFNS----SQQDYPSYPSFGQGQYAQYYNSSPYPA 237
                    TT++     N++ T SS   +    ++    +  +   G  A   +S+P   
Sbjct: 5109 THTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTAT-LSSTPGTT 5167

Query: 238  HYMTSSNTSPT-------TPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPST 285
              +T  +T  T       T + ++T      P  +T+ A T PTA  ST+ S ST
Sbjct: 5168 WILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMA-TMPTATASTVPSSST 5221



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 63/274 (22%), Positives = 99/274 (36%), Gaps = 42/274 (15%)

Query: 32   SNSMTPNGTEVKTEPMSSSETAST----TADGSLNNFSGSAIGSSSFSPRPTHQFSPPQI 87
            S + TP  T     P S+ ETA T    TA  +    +GS + + S +P   H    P  
Sbjct: 2689 SQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGS-VATPSSTPGTAHTTKVPTT 2747

Query: 88   YPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIK 147
              +         TPSS    A     + +     T   +   P    G +    +     
Sbjct: 2748 TTTG-----FTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTT 2802

Query: 148  T---EGGLSQSQSPGQTGFLSYGTSFSTPQPGQ---------APYSYQMQGSSFTTSSGI 195
            T    G ++   S  QT     GT+ + P P            P S     +++T+++  
Sbjct: 2803 TTVATGSMATPSSSTQTS----GTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSG 2858

Query: 196  YTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSP--TTPS-T 252
              G   +T  S   S    +    + G  Q++    SSP+P+   T S  SP  TTP  T
Sbjct: 2859 ILGTTHITEPSTVTS----HTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHT 2914

Query: 253  NATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTP 286
             AT +         + A   P+   ++   PS+P
Sbjct: 2915 TATSR---------TTATATPSKTRTSTLLPSSP 2939


>gi|5454064 RNA binding motif protein 14 [Homo sapiens]
          Length = 669

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 67/280 (23%), Positives = 108/280 (38%), Gaps = 35/280 (12%)

Query: 15  GSSESPSGPKLGNSHINSNSMTPNGTEVK---TEPMSSSETASTTADGSLNNFSGSAIGS 71
           G +  P+ P  G          P  + V     +P +     S +   +      +++G 
Sbjct: 200 GQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQPSVSLGAAYRAQPSASLGV 259

Query: 72  SSFSPRPTHQFSPPQIYPS---NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATY- 127
              +   T Q +  +  PS     PY   L +PSSQ+ AA     +      A+A ++Y 
Sbjct: 260 GYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGAQPSASALSSYG 319

Query: 128 PQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYG-----TSFSTPQPGQAPYSY 182
            Q      ++SYGA  + + + G  +Q  S G     SYG     +S++T     +  SY
Sbjct: 320 GQAAAASSLNSYGAQGSSLASYG--NQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSY 377

Query: 183 QMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQY-YNSSPYPAHYMT 241
             Q +S+        G  S  +S  + +    Y + PS      A Y   S+PY A    
Sbjct: 378 GAQAASY--------GAQSAASSLAYGAQAASYNAQPS------ASYNAQSAPYAAQQAA 423

Query: 242 SSNTSPTT----PSTNATYQLQEPPSGITSQAVTDPTAEY 277
           S ++ P      P+T A Y  Q  P+   +QA T     Y
Sbjct: 424 SYSSQPAAYVAQPATAAAYASQ--PAAYAAQATTPMAGSY 461


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 70/289 (24%), Positives = 110/289 (38%), Gaps = 42/289 (14%)

Query: 56  TADGSLNNFSGSAIGSSSFSPRPTHQFSPP-QIYPSNRPYPHILPTPSS----QTMAAYG 110
           + D S  + + +  G S+++ +PT  ++   Q Y       +  PT  S    QT A YG
Sbjct: 3   STDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62

Query: 111 QTQFTTGMQQ-------ATAYAT------YPQPGQPYGISSYGALWAGIKTEGGLSQSQS 157
           QT + T   Q       +T Y T      Y QP Q YG  +Y    A + T      +QS
Sbjct: 63  QTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQS 122

Query: 158 PGQTGFLSYGTSFSTPQPGQAPY----SYQMQGSSFTTSSGIYTGNNSLTNSS-GFNSSQ 212
                  +YGT  + P  GQ P     +    G+  T +S   +        S G+  S 
Sbjct: 123 -------AYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSN 175

Query: 213 QDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQE---PPSGITSQA 269
             YP  P    G Y     ++P P++  TS +++  T    ++Y  Q     PS    Q+
Sbjct: 176 YSYPQVP----GSYPMQPVTAP-PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQS 230

Query: 270 VTDPTAEYS----TIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPS 314
                + Y     T + P T        +  + S    +    R ++PS
Sbjct: 231 SYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPS 279


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 65/298 (21%), Positives = 111/298 (37%), Gaps = 28/298 (9%)

Query: 6   LTSPHSRLSGSSESPSGPKLGNSHINS-NSMTPNGTEVKTEPMSSSETASTTADGSLNNF 64
           L SPH+   G    P GP+ G +   S +S+ P  +     PM    ++S+++  + ++ 
Sbjct: 329 LPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSS 388

Query: 65  SGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAY 124
           S S+  SSS SP P  Q  P         YPH  P P+S +++          +     +
Sbjct: 389 SSSS--SSSASPFPASQALPS--------YPHSFPPPTSLSVSNQPPKYTQPSLPSQAVW 438

Query: 125 ATYPQPGQPYG---ISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYS 181
           +  P P  PYG    +S         + G  S +  P  T    +       Q  Q    
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQ 498

Query: 182 YQMQ--GSSFTTSSGIYTGNNSLTNSSGFNS----------SQQDYPSYPSFGQGQYAQY 229
            Q Q  G+S     G +   + L   S  ++          S + YP  P+     ++Q 
Sbjct: 499 QQQQHHGNSGPPPPGAFP--HPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQV 556

Query: 230 YNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287
             S   P     SS+++ ++ ++  +Y    P      Q    P     T+ + S  +
Sbjct: 557 SYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATL 614



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 72/283 (25%), Positives = 99/283 (34%), Gaps = 86/283 (30%)

Query: 6   LTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFS 65
           L  PHS++S S   P+GP +                      SSS ++S+T+ GS     
Sbjct: 549 LPPPHSQVSYSQAGPNGPPVS---------------------SSSNSSSSTSQGSY---- 583

Query: 66  GSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYA 125
                       P    SP Q  P   PYP   P P+  T +A   T   T       Y 
Sbjct: 584 ------------PCSHPSPSQ-GPQGAPYP-FPPVPTVTTSSATLSTVIATVASSPAGYK 629

Query: 126 TYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQ 185
           T   PG P     YG             ++ SPG     +Y T  +TP PG  P      
Sbjct: 630 TASPPGPP----PYG------------KRAPSPG-----AYKT--ATP-PGYKP------ 659

Query: 186 GSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNT 245
           GS  +  +G   G    +  +G  + +   P  P+ G G         P P    +   +
Sbjct: 660 GSPPSFRTGTPPGYRGTSPPAGPGTFK---PGSPTVGPG---------PLPPAGPSGLPS 707

Query: 246 SPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIK 288
            P  P+  A+     PP   T Q   +P  EY T  SP  P +
Sbjct: 708 LPPPPAAPAS----GPPLSAT-QIKQEPAEEYETPESPVPPAR 745



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 43/170 (25%), Positives = 62/170 (36%), Gaps = 38/170 (22%)

Query: 50  SETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYP---------------SNRPY 94
           S + S  + GS+ N S S+ G S    RP H   PP ++P               S  P+
Sbjct: 130 STSPSIYSPGSVENDSDSSSGLSQGPARPYH---PPPLFPPSPQPPDSTPRQPEASFEPH 186

Query: 95  PHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQP------------GQPYGISSYGAL 142
           P + PT     M        T+ M QA   A  P P            G P G    GA 
Sbjct: 187 PSVTPTGYHAPMEPP-----TSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAA 241

Query: 143 WAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTS 192
            +     GG    Q P  T  +S  +S ++  P   P +  + G +  ++
Sbjct: 242 SSVGGPNGG---KQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSA 288


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 65/298 (21%), Positives = 111/298 (37%), Gaps = 28/298 (9%)

Query: 6   LTSPHSRLSGSSESPSGPKLGNSHINS-NSMTPNGTEVKTEPMSSSETASTTADGSLNNF 64
           L SPH+   G    P GP+ G +   S +S+ P  +     PM    ++S+++  + ++ 
Sbjct: 329 LPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSS 388

Query: 65  SGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAY 124
           S S+  SSS SP P  Q  P         YPH  P P+S +++          +     +
Sbjct: 389 SSSS--SSSASPFPASQALPS--------YPHSFPPPTSLSVSNQPPKYTQPSLPSQAVW 438

Query: 125 ATYPQPGQPYG---ISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYS 181
           +  P P  PYG    +S         + G  S +  P  T    +       Q  Q    
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQ 498

Query: 182 YQMQ--GSSFTTSSGIYTGNNSLTNSSGFNS----------SQQDYPSYPSFGQGQYAQY 229
            Q Q  G+S     G +   + L   S  ++          S + YP  P+     ++Q 
Sbjct: 499 QQQQHHGNSGPPPPGAFP--HPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQV 556

Query: 230 YNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287
             S   P     SS+++ ++ ++  +Y    P      Q    P     T+ + S  +
Sbjct: 557 SYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATL 614



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 72/283 (25%), Positives = 99/283 (34%), Gaps = 86/283 (30%)

Query: 6   LTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFS 65
           L  PHS++S S   P+GP +                      SSS ++S+T+ GS     
Sbjct: 549 LPPPHSQVSYSQAGPNGPPVS---------------------SSSNSSSSTSQGSY---- 583

Query: 66  GSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYA 125
                       P    SP Q  P   PYP   P P+  T +A   T   T       Y 
Sbjct: 584 ------------PCSHPSPSQ-GPQGAPYP-FPPVPTVTTSSATLSTVIATVASSPAGYK 629

Query: 126 TYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQ 185
           T   PG P     YG             ++ SPG     +Y T  +TP PG  P      
Sbjct: 630 TASPPGPP----PYG------------KRAPSPG-----AYKT--ATP-PGYKP------ 659

Query: 186 GSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNT 245
           GS  +  +G   G    +  +G  + +   P  P+ G G         P P    +   +
Sbjct: 660 GSPPSFRTGTPPGYRGTSPPAGPGTFK---PGSPTVGPG---------PLPPAGPSGLPS 707

Query: 246 SPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIK 288
            P  P+  A+     PP   T Q   +P  EY T  SP  P +
Sbjct: 708 LPPPPAAPAS----GPPLSAT-QIKQEPAEEYETPESPVPPAR 745



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 43/170 (25%), Positives = 62/170 (36%), Gaps = 38/170 (22%)

Query: 50  SETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYP---------------SNRPY 94
           S + S  + GS+ N S S+ G S    RP H   PP ++P               S  P+
Sbjct: 130 STSPSIYSPGSVENDSDSSSGLSQGPARPYH---PPPLFPPSPQPPDSTPRQPEASFEPH 186

Query: 95  PHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQP------------GQPYGISSYGAL 142
           P + PT     M        T+ M QA   A  P P            G P G    GA 
Sbjct: 187 PSVTPTGYHAPMEPP-----TSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAA 241

Query: 143 WAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTS 192
            +     GG    Q P  T  +S  +S ++  P   P +  + G +  ++
Sbjct: 242 SSVGGPNGG---KQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSA 288


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 76/340 (22%), Positives = 123/340 (36%), Gaps = 33/340 (9%)

Query: 7    TSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSG 66
            TSP    +  S SP+ P    +  + +  +P+ +        +S + S T+         
Sbjct: 1639 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1698

Query: 67   SAIGSSSFSPR-PTHQFSPPQIYPSNRPYPHILPT--PSSQTMAAYGQTQFTTGMQQATA 123
             +  S S+SP  P++  + P   P++  Y    P+  P+S + +        T       
Sbjct: 1699 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPT 1758

Query: 124  YATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYS-- 181
              +Y      Y  +S              S + SP    +     S+S   P  +P S  
Sbjct: 1759 SPSYSPTSPSYSPTS--------PNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPR 1810

Query: 182  YQMQGSSFTTSSGIYTGNN---SLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPY--- 235
            Y  Q  ++T SS  Y+ ++   S T+     +S    PS P +      +Y  +SP    
Sbjct: 1811 YTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTS-PKYSPTSPKYSP 1869

Query: 236  --PAHYMTSSNTSPTTPS---TNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDS 290
              P +  TS   SPTTP    T+ TY    P    TS   +  +  YS      +P   +
Sbjct: 1870 TSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPT 1929

Query: 291  DSDRLRRGSDGKSRGRGRRNNNPS--------PPPDSDLE 322
             S    +GS       G    +P+         P DSD E
Sbjct: 1930 YSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEE 1969



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 70/289 (24%), Positives = 103/289 (35%), Gaps = 28/289 (9%)

Query: 9    PHSRLSGSSESPSGPKLGNSHINSNSMTP-NGTEVKTEPMSSSETASTTADGSLNNFSGS 67
            P     GS+ SP G         S +MTP N          S    S    G+      +
Sbjct: 1498 PTGMFFGSAPSPMGGI-------SPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSA 1550

Query: 68   AIGSSSFSPRPTHQFSPPQIYP-SNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYAT 126
            A  +S FSP  +  +SP    P S  P    +P+P      +Y  T        + AY  
Sbjct: 1551 ASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPT--------SPAY-- 1600

Query: 127  YPQPGQPYGISSYGALWAGIKTE-GGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYS--YQ 183
              +P  P G +     ++         S S SP    +     S+S   P  +P S  Y 
Sbjct: 1601 --EPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYS 1658

Query: 184  MQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSS 243
                S++ +S  Y    S T+ S   +S    P+ PS+     +    S  Y     + S
Sbjct: 1659 PTSPSYSPTSPSY----SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1714

Query: 244  NTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDS 292
             TSP+   T+ +Y    P    TS + +  +  YS      TP   S S
Sbjct: 1715 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYS 1763


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 72/287 (25%), Positives = 119/287 (41%), Gaps = 18/287 (6%)

Query: 13  LSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSS 72
           ++ +SES +     ++  NS S TP+ +   T   S S T S+ A  + N+ S +   +S
Sbjct: 104 IATNSESSTTSSGASTATNSESSTPS-SGASTATNSDSSTTSSGASTATNSDSST---TS 159

Query: 73  SFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQ 132
           S +   T+  S      ++        T SS+   A      TT    +TA  +  +   
Sbjct: 160 SEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESR--- 216

Query: 133 PYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTS 192
               +S G   AG  T    S + S   T   +  +  STP  G A  +   + S+ ++ 
Sbjct: 217 ---TTSNG---AGTATNSESSTTSSGAST---ATNSESSTPSSG-AGTATNSESSTTSSG 266

Query: 193 SGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPST 252
           +G  T + S T SSG ++      S PS G    A    SS   +   T++N+  +T S+
Sbjct: 267 AGTATNSESSTVSSGISTVTNSESSTPSSG-ANTATNSESSTTSSGANTATNSDSSTTSS 325

Query: 253 NATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGS 299
            A+       S  +S A T   +E ST  S ++   +S S     G+
Sbjct: 326 GASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGT 372



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 73/309 (23%), Positives = 122/309 (39%), Gaps = 20/309 (6%)

Query: 7   TSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSG 66
           TS  +  + +SES +     ++  NS+S T   T       ++S++++T+++ S    S 
Sbjct: 113 TSSGASTATNSESSTPSSGASTATNSDSST---TSSGASTATNSDSSTTSSEASTATNSE 169

Query: 67  SAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFT-----TGMQQA 121
           S+  SS  S     + S      S         T S  + A   +++ T     T     
Sbjct: 170 SSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSE 229

Query: 122 TAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQS------PGQTGFLSYGTSFSTPQP 175
           ++  +          SS  +  AG  T    S + S        ++  +S G S  T   
Sbjct: 230 SSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSE 289

Query: 176 GQAPYS---YQMQGSSFTTSSGIYTGNN--SLTNSSGFNSSQQDYPSYPSFGQGQYAQYY 230
              P S         S TTSSG  T  N  S T SSG +++     S  S G    A   
Sbjct: 290 SSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSG-ASTATNS 348

Query: 231 NSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDS 290
            SS   +   T++N+  +T S+  +       S ++S A T  T+E ST  S ++   +S
Sbjct: 349 ESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNS 408

Query: 291 DSDRLRRGS 299
           +S  +  G+
Sbjct: 409 ESSTVSSGA 417



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 62/289 (21%), Positives = 119/289 (41%), Gaps = 14/289 (4%)

Query: 14  SGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSS 73
           + S+E+ +    G+S I+S + T           ++S ++ T++  S    SGS++ S+ 
Sbjct: 22  TNSNETSTSANTGSSVISSGASTA----------TNSGSSVTSSGVSTATISGSSVTSNG 71

Query: 74  FSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTT-GMQQAT-AYATYPQPG 131
            S     +F       S           S  ++A   ++  T+ G   AT + ++ P  G
Sbjct: 72  VSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSG 131

Query: 132 QPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTT 191
                +S  +  +   +    S S +       +  +  ST   G A  +   + S+ ++
Sbjct: 132 ASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSG-ASTATNSESSTVSS 190

Query: 192 SSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPS 251
            +   T + S T SSG +++        S G G  A    SS   +   T++N+  +TPS
Sbjct: 191 RASTATNSESSTTSSGASTATNSESRTTSNGAGT-ATNSESSTTSSGASTATNSESSTPS 249

Query: 252 TNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSD 300
           + A        S  +S A T   +E ST+ S  + + +S+S     G++
Sbjct: 250 SGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGAN 298



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 75/340 (22%), Positives = 133/340 (39%), Gaps = 33/340 (9%)

Query: 14  SGSSESPSGPKLGNSHINSNSMTPNGTEVKTEP-----------MSSSETASTTADGSLN 62
           SGSS + SG  +  + I+ +S+T NG  + T              ++SE ++ ++  S+ 
Sbjct: 48  SGSSVTSSG--VSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIA 105

Query: 63  NFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQAT 122
             S S+  SS  S     + S P    S         T S  + A    +  TT  + +T
Sbjct: 106 TNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSS-TTSSEAST 164

Query: 123 AY----------ATYPQPGQPYGISSYGALWAGIKTE----GGLSQSQSPGQTGFLSYGT 168
           A           A+     +   +SS  +     ++     G  + + S  +T     GT
Sbjct: 165 ATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGT 224

Query: 169 ---SFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQ 225
              S S+     A  +   + S+ ++ +G  T + S T SSG  ++     S  S G   
Sbjct: 225 ATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGIST 284

Query: 226 YAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPST 285
                +S+P  +   T++N+  +T S+ A        S  +S A T   +E ST  S ++
Sbjct: 285 VTNSESSTP-SSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAS 343

Query: 286 PIKDSDSDRLRRG-SDGKSRGRGRRNNNPSPPPDSDLERV 324
              +S+S     G S   + G    ++  S   +S+   V
Sbjct: 344 TATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTV 383



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 55/234 (23%), Positives = 85/234 (36%), Gaps = 13/234 (5%)

Query: 7   TSPHSRLSGSSESPSGPKLGNSHINSNSMTPN---GTEVKTEPMSSSETASTTADGSLNN 63
           TS  +  + +SES +     ++  NS S TP+   GT   +E  ++S  A T  +   + 
Sbjct: 218 TSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESST 277

Query: 64  FSG--SAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQA 121
            S   S + +S  S   +   +      S         T S  +  + G +  T      
Sbjct: 278 VSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESST 337

Query: 122 TAYATYPQPGQPYGISSYGALWA---GIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQA 178
           T+             +S GA  A   G  T    + + +  ++  +S G S +T      
Sbjct: 338 TSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESST 397

Query: 179 PYS---YQMQGSSFTTSSGIYTGNNS--LTNSSGFNSSQQDYPSYPSFGQGQYA 227
             S         S T SSG  T  NS   T SSG N++     S  S G G  A
Sbjct: 398 TSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAA 451


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 72/303 (23%), Positives = 118/303 (38%), Gaps = 34/303 (11%)

Query: 33   NSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIY-PSN 91
            NS+ P+G    +  +SS + AS TA         +A+ S+   P  + QFS P  + PS 
Sbjct: 1170 NSLKPSGPTPASGQLSSGDKASGTAKIE------TAVTST---PSASGQFSKPFSFSPSG 1220

Query: 92   RPYPH--ILPTPSSQTMAAYGQT----------QFTTGMQQATAYATYPQPGQPYGISSY 139
              +    I PTPSS   AA G T           F++G     +Y   P+   P GI+S 
Sbjct: 1221 TGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSA 1280

Query: 140  GALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTP--QPGQAPYSYQMQGSSFTTSSGIYT 197
                 G +     S+  +P  T   +  +   TP  + G+  +   + G +  + SG+  
Sbjct: 1281 SNTTPG-EPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRV 1339

Query: 198  GN-NSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATY 256
            G  +  T  +   SS     + P+   G  + +  ++P     +   +T P  P T++  
Sbjct: 1340 GQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAP----PVLGKHTEP--PVTSSAT 1393

Query: 257  QLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNN--PS 314
                 P   TS + T          + S+ +       L  G    S G  + N+   PS
Sbjct: 1394 TTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPS 1453

Query: 315  PPP 317
             PP
Sbjct: 1454 APP 1456



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 52/206 (25%), Positives = 83/206 (40%), Gaps = 17/206 (8%)

Query: 33   NSMTPNGTEVKTEPMSSSETASTTADGSLNN--FSGSAIGSSSFSPRPTHQFSPP--QIY 88
            +S  P   E  + P++SS T+      S     F     GSS F+  P    S    Q+ 
Sbjct: 1602 SSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLT 1661

Query: 89   PSNRPYPHILPT----PSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWA 144
             +    P   P      +S   + +GQ    TG   +TA AT       +   ++G    
Sbjct: 1662 NNTATAPSATPVFGQVAASTAPSLFGQQ---TGSTASTAAATPQVSSSGFSSPAFGTTAP 1718

Query: 145  GIKTEGGLSQSQSPGQTGFLSYGT-SFSTPQPGQAPYSYQMQGSSFTTSSG-IYTGNNSL 202
            G+  +    Q+   GQ+   +    SFS P     P   Q   S+ T++SG ++   +S 
Sbjct: 1719 GVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASST 1778

Query: 203  TNSSGFNSSQQDYPSYPSFGQGQYAQ 228
            ++SS F+  Q    S P+ G G + Q
Sbjct: 1779 SSSSSFSFGQ----SSPNTGGGLFGQ 1800



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 55/222 (24%), Positives = 80/222 (36%), Gaps = 35/222 (15%)

Query: 48  SSSETASTTADGSLNNFSGSAIGSSSFSPRP---THQFSPPQIYPSNRPYPHILPTPSSQ 104
           SSS  +S T  G   ++S S   SS  +P P   T  F PP    S  P P   P   S 
Sbjct: 486 SSSLKSSATVTGEPPSYS-SGSDSSKAAPGPGPSTFSFVPPS-KASLAPTPAASPVAPSA 543

Query: 105 TMAAYGQTQF-----TTGMQQATAYATYPQPGQPYGIS----SYGALWAGIKTEGGLSQS 155
              ++G + F     +T +   +A     +P  P   S    +    +    T   +S S
Sbjct: 544 ASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSS 603

Query: 156 QS------------PGQTGFLSYGTSFSTPQPG--------QAPYSYQMQGSSFTTSSGI 195
           QS            P  +G LS+ T  S P            +P     QGSS    S +
Sbjct: 604 QSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVPSMV 663

Query: 196 YTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPA 237
              +  +T  +    S Q     P+  + Q  Q+ +S P  A
Sbjct: 664 QK-SPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMA 704


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 57/198 (28%), Positives = 75/198 (37%), Gaps = 35/198 (17%)

Query: 119 QQAT-AYATYP-QPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPG 176
           QQAT +Y  YP QPGQ Y   S                SQ  GQ  +  Y  S  T   G
Sbjct: 8   QQATQSYGAYPTQPGQGYSQQS----------------SQPYGQQSYSGYSQSTDTSGYG 51

Query: 177 QAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQY--YNSSP 234
           Q+  SY   G S  T  G  +      ++ G+ SSQ    SY     GQ + Y  Y   P
Sbjct: 52  QS--SYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSY-----GQQSSYPGYGQQP 104

Query: 235 YPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQ--AVTDPTAEYSTIHSPSTPIKDSDS 292
            P      S+TS +  S++ +    +P SG  SQ  +       Y    S + P      
Sbjct: 105 AP------SSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQ 158

Query: 293 DRLRRGSDGKSRGRGRRN 310
           ++    S G   G G  N
Sbjct: 159 NQYNSSSGGGGGGGGGGN 176


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 72/294 (24%), Positives = 117/294 (39%), Gaps = 33/294 (11%)

Query: 14   SGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSE--TASTTADGSLNNFSGSA-IG 70
            S S+   +   + ++H  + S   +G    +EP SS    T++ TA  S +  SG+   G
Sbjct: 759  SASTSPDTAAAMTHTH-QAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSG 817

Query: 71   SSSFSPR-PTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATY-- 127
            S   S    T +FS     PS   +     T      A++G    +TGM  +    T+  
Sbjct: 818  SEGISTSGETTRFSSN---PSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHP 874

Query: 128  -----PQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSY 182
                    G+P G SS              S S SP +T  +S        +  +   + 
Sbjct: 875  TLSEASTAGRPTGQSS------------PTSPSASPQETAAISRMAQTQRTRTSRGSDTI 922

Query: 183  QMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQY---AQYYNSSPYPAHY 239
             +   +  T S +     S+T S+G  S Q +  +    G G+    A   N++P P  Y
Sbjct: 923  SLASQATDTFSTVPPTPPSIT-STGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTY 981

Query: 240  MTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSD 293
             +S++T  TTP  + T          T   VT P++  ST H+   P+ D+ S+
Sbjct: 982  ASSASTGHTTP-LHVTDASSVSTGHATPLPVTSPSS-VSTGHTTPLPVTDTSSE 1033



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 53/279 (18%), Positives = 114/279 (40%), Gaps = 21/279 (7%)

Query: 14  SGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSS 73
           SG + + S   + N+ + ++ +    T  +   + ++E  S +  G+++  + S + +  
Sbjct: 372 SGETTTSSPSSVSNTFLVTSKVFRMPTS-RDSTLGNTEETSLSVSGTISAIT-SKVSTIW 429

Query: 74  FSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAA-YGQTQFTTGMQQATAYATYPQPGQ 132
           +S   +   SP  + P      H   +  ++T    + ++ F+ G+ Q   +  +     
Sbjct: 430 WSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRPHERSSFSPGVSQEI-FTLHETTTW 488

Query: 133 PYGISSYG-ALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTT 191
           P   SS G   W+  +     + + +   TG  S GT+ + P+      +    G   T 
Sbjct: 489 PSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTY 548

Query: 192 SSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPS 251
           SS     + +L  ++G  +  Q      + G+   +        P++ +T    + T+PS
Sbjct: 549 SSH----STTLPKTTGAGAQTQWTQETGTTGEALLSS-------PSYSVTQMIKTATSPS 597

Query: 252 TNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDS 290
           ++            + Q  T P+  +STIHS ST  ++S
Sbjct: 598 SSPMLDRHT-----SQQITTAPSTNHSTIHSTSTSPQES 631



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 61/288 (21%), Positives = 110/288 (38%), Gaps = 57/288 (19%)

Query: 32   SNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPT---------HQF 82
            S++ T + T +    +SS+ T   T    L   S S+  +   +P P          H  
Sbjct: 3783 SSASTDDTTRLPVTDVSSASTGHATP---LPVTSTSSASTGDTTPLPVTDTSSVSTGHAT 3839

Query: 83   SPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGAL 142
            S P    S+    H  P P + T +             +T +AT      P  ++S  ++
Sbjct: 3840 SLPVTSRSSASTGHATPLPVTDTSSV------------STGHAT------PLPVTSTSSV 3881

Query: 143  WAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSS---FTTSSGIYTGN 199
              G  T   ++   S          T  +TP P  +  S     ++    T +S + TG+
Sbjct: 3882 STGHATPLPVTSPSSAS--------TGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGH 3933

Query: 200  NSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTP----STNAT 255
             +  + +  +S+ +   S         A   +++P P   ++S +T  TTP     T++ 
Sbjct: 3934 ATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSA 3993

Query: 256  YQLQEPPSGITSQA-----------VTDPTAEYSTIHSPSTPIKDSDS 292
               Q  P  +TS +           VT P++  S+ H+ S P+ D+ S
Sbjct: 3994 STGQATPLPVTSLSSVSTGDTTPLPVTIPSSA-SSGHTTSLPVTDASS 4040


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo
           sapiens]
          Length = 1758

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 22/177 (12%)

Query: 84  PPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALW 143
           PP +YP   P PH LP P       +   QF  G      Y+  P PG P   ++    W
Sbjct: 561 PPPLYP---PPPHTLPLPPGVPPPQFSP-QFPPGQPPPAGYSV-PPPGFPPAPANLSTPW 615

Query: 144 --AGIKT--EGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGN 199
             +G++T     +  +Q+P  +    Y       +  ++PYS    GSS++ SS  Y+ +
Sbjct: 616 VSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYS----GSSYSRSSYTYSKS 671

Query: 200 NS-LTNSSGFNSS-----QQDY---PSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSP 247
            S  T S  ++ S      + Y   P YP  G+G+   Y + S    ++ + S + P
Sbjct: 672 RSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPP 728


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 71/300 (23%), Positives = 113/300 (37%), Gaps = 29/300 (9%)

Query: 6    LTSPH-SRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNF 64
            +TSP  S LS +    + P   ++ ++S+     GT + T   S   T  T+   S    
Sbjct: 818  VTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLV 877

Query: 65   SGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAY 124
            + SAI + S +P  T           + P  +     SS T +       +T  + +T  
Sbjct: 878  ATSAISTLSTTPVDT-----------STPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPL 926

Query: 125  ATYPQPGQPYGISSYGALWAG-IKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQA----- 178
             + P    P   S    L A  + T   ++ S     +   + GTS  T  P +      
Sbjct: 927  TSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLT 986

Query: 179  --PYSYQMQGSS--FTTSSGIYTGNNSLTNSSGFNSSQQDYP------SYPSFGQGQYAQ 228
              P S+ +  +S   T S+     N  LT S+  +S            S PS G     +
Sbjct: 987  STPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTR 1046

Query: 229  YYNSSPYPAHYMTSS-NTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287
               S+   A   TS+ +T+P   ST  T   Q   S  T+   + PT+ YS   +P T +
Sbjct: 1047 MPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSV 1106



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 63/294 (21%), Positives = 112/294 (38%), Gaps = 28/294 (9%)

Query: 11   SRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIG 70
            S LS +    + P + ++ ++S+ +   GT ++T   S   T  T+   S    + SAI 
Sbjct: 2120 STLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAIS 2179

Query: 71   SSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQP 130
            + S +P  T           + P  +     SS T +       +T  + +T + + P  
Sbjct: 2180 TLSTTPVDT-----------STPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVS 2228

Query: 131  GQPYGISSYGALWA-GIKTEGGLSQSQSPGQTGFLSYGTSF--STPQPGQAPYSYQMQGS 187
              P   S    L A  + T   ++ S     +   + GTS   ST   G  P +      
Sbjct: 2229 TMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSH 2288

Query: 188  SFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSS-------------P 234
            +   +S + T + +  +S+   ++  +  S P   +G       SS              
Sbjct: 2289 TLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTT 2348

Query: 235  YPAHYMTSS-NTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287
              A + TS+ +T+P   ST  T   Q   S  T+   + PT+ YS   +P T +
Sbjct: 2349 MVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSV 2402



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 64/274 (23%), Positives = 102/274 (37%), Gaps = 33/274 (12%)

Query: 27   NSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSS-------SFSPRPT 79
            +S +N+ S TP  +       + + ++ T A+G+    S ++ GS+       S +P  +
Sbjct: 3413 SSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVAS 3472

Query: 80   HQFSPPQIYP--SNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGIS 137
             + S     P  ++ P     PT SS T A       +T  + +T     P    P   S
Sbjct: 3473 SEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASS 3532

Query: 138  SYGALWAGIKTEGGL--SQSQSPGQTGFLSYGT-SFSTPQPGQAPYSYQMQGSSFTTSSG 194
                L            S SQ+      L   T   STP  G +  +  +  S++ TSS 
Sbjct: 3533 EASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSE 3592

Query: 195  IYTGNN-SLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTN 253
              T +  S+  S+   +S Q                 NS+P P   +T   ++P+  ST 
Sbjct: 3593 ASTPSTPSVDRSTPVTTSTQS----------------NSTPTPPEVITLPMSTPSEVSTP 3636

Query: 254  ATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287
             T       S   S+A T  T    T    STP+
Sbjct: 3637 LTIMPVSTTSVTISEAGTASTLPVDT----STPV 3666



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 69/300 (23%), Positives = 109/300 (36%), Gaps = 34/300 (11%)

Query: 16   SSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFS 75
            +S S S   + +S  ++ S TP  T       + + ++ TTA+G+    S  + GS+  +
Sbjct: 2990 TSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLT 3049

Query: 76   --PRPTHQFSPPQI-------YPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYAT 126
              P  T   + P+          SN P        SS T A       +T  + +T    
Sbjct: 3050 SIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTG 3109

Query: 127  YPQPGQPYGISSYGAL-WAGIKTEGGLSQSQSPGQTGFLSYGTSF--STPQPGQAPYSYQ 183
             P    P   S+   L    + T   ++ S     +   S GTS   STP  G  P +Y 
Sbjct: 3110 VPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYM 3169

Query: 184  MQGSSFTTSS--------GIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPY 235
               +    SS         + T     T++   +S+  +  S P+    +      S P 
Sbjct: 3170 PVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPV 3229

Query: 236  PAHYMTSSNTS--------PTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287
                + SS  S          TP T +T     PP   T++  + PT   ST    STP+
Sbjct: 3230 SNTPVASSEASILSTTPVDSNTPLTTSTEASSSPP---TAEGTSMPT---STPSEGSTPL 3283



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 67/308 (21%), Positives = 123/308 (39%), Gaps = 30/308 (9%)

Query: 5    DLTSPHSRLSGSSESPS---GPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSL 61
            D ++P +  + +  SP+   G  + NS+ +  +       V T P+ SSE ++ +A    
Sbjct: 1363 DNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVD 1422

Query: 62   NNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYP-HILPTPSSQTMAAYGQTQFTTGMQQ 120
             +  G+    ++ SP      S P   PS    P   +P  ++    +   T  TT +  
Sbjct: 1423 TSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDS 1482

Query: 121  ------ATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLS---YGTSFS 171
                  +TA ++ P P +   I+          +EG  + +  P  T  ++     +  +
Sbjct: 1483 NSPVVTSTAVSSSPTPAEGTSIA------ISTPSEGSTALTSIPVSTTTVASSEINSLST 1536

Query: 172  TPQPGQAPY-SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYY 230
            TP     P  +Y    SS TT+ G  T   + T S G ++     P          A   
Sbjct: 1537 TPAVTSTPVTTYSQASSSPTTADG--TSMQTSTYSEG-STPLTSLPVSTMLVVSSEANTL 1593

Query: 231  NSSPYPAHYMTSSNT--SPTTPSTNATYQLQEPPSG---ITSQAV-TDPTAEYSTIHSPS 284
            +++P  +    +++T  S +T +  ++  +  P  G   +TS  V T P A        +
Sbjct: 1594 STTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLST 1653

Query: 285  TPIKDSDS 292
            TP+ DS+S
Sbjct: 1654 TPV-DSNS 1660



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 68/297 (22%), Positives = 108/297 (36%), Gaps = 29/297 (9%)

Query: 7   TSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSG 66
           +S  S LS +    S P   +S  +S+S TP GT + T   S   T  T    S      
Sbjct: 525 SSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVS 584

Query: 67  SAIGSSSFSPRPTHQF-------SPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQ 119
           S   ++S +P  ++ F       S           P    +    T+ +   +       
Sbjct: 585 SEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASS 644

Query: 120 QATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAP 179
           +A+  +T P        +S         TE   S + + G +   S  T  STP     P
Sbjct: 645 EASTLSTTPVDSNTPVTTS---------TEATSSSTTAEGTSMPTSTYTEGSTPLTSM-P 694

Query: 180 YSYQMQGSS--FTTSSGIYTGNNSLTNSSGFNSS--QQDYPSYPSFGQGQYAQYYNSSPY 235
            +  +  SS   T S+     +  +T S+  +SS    D  S P+    + +    S P 
Sbjct: 695 VNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPV 754

Query: 236 PAHYMTSS--NTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDS 290
               +TSS  +T  TTP   +T+         +++A   PT    T    STP + S
Sbjct: 755 SKTLLTSSEASTLSTTPLDTSTH------ITTSTEASCSPTTTEGTSMPISTPSEGS 805



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 60/298 (20%), Positives = 109/298 (36%), Gaps = 22/298 (7%)

Query: 7   TSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSG 66
           +S  S LS +    + P   ++   S+S T  GT + T   +   T  T+   +    + 
Sbjct: 643 SSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVAS 702

Query: 67  SAIGSSSFSPRPTHQFSPPQIYPSNRP-------YPHILPTPSSQTMAAYGQTQFTTGMQ 119
           S   + S +P  T          S+ P        P   P+  S  + +   ++      
Sbjct: 703 SEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSS 762

Query: 120 QATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAP 179
           +A+  +T P     +  +S  A  +   TEG      +P +      G+   T  P    
Sbjct: 763 EASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSE------GSPLLTSIPVSIT 816

Query: 180 YSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQ--DYPSYPSFGQGQYAQYYNSSPYPA 237
                + S+ +T+      N+ +T S+  +SS    +  S P+    +      S P   
Sbjct: 817 PVTSPEASTLSTTP--VDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVST 874

Query: 238 HYMTSS-----NTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDS 290
             + +S     +T+P   ST  T   +   S  TS+  + PT+      +P T + DS
Sbjct: 875 TLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDS 932



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 70/342 (20%), Positives = 126/342 (36%), Gaps = 65/342 (19%)

Query: 3    MQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLN 62
            MQ  T    R   +S   S   + +S I++ S TP  T       + + ++ TT++G+  
Sbjct: 2151 MQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM 2210

Query: 63   NFSGSAIGSSSFSPRP-------THQFSPPQIYPSNRPYPHILPT--------------- 100
              S  + GS+ F+  P       T + S     P +   P    T               
Sbjct: 2211 PTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 2270

Query: 101  --------------PSSQTMAAYGQ--TQFTTGMQQATAYATYPQPGQPYGISSYGALWA 144
                          P S T+ A  +  T  TT +   T + T  +   P   +   ++  
Sbjct: 2271 TSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPT 2330

Query: 145  GIKTEGGLSQSQSPGQTGFL-SYGTS--FSTPQPGQAPY-SYQMQGSSFTTSSGIYTGNN 200
               +EG    ++ P  T  + S+ TS   +TP     P  +Y   GSS TT+      ++
Sbjct: 2331 STSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTA------DD 2384

Query: 201  SLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQE 260
            +   +S ++       S P           ++ P  +   ++ +T+P   ST  T   + 
Sbjct: 2385 TSMPTSTYSEGSTPLTSVP----------VSTMPVVSSEASTHSTTPVDTSTPVTTSTEA 2434

Query: 261  PPSGITSQAVTDPTAEYSTIHSP-------STPIKDSDSDRL 295
              S  T++  + PT+  S   +P       +TP+  S++  L
Sbjct: 2435 SSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTL 2476



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 70/309 (22%), Positives = 111/309 (35%), Gaps = 36/309 (11%)

Query: 11   SRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIG 70
            S LS +    + P + ++ ++S+     GT +     S   T  T    S    + SAI 
Sbjct: 3064 STLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAIS 3123

Query: 71   SSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQP 130
            + S +P  T   S P    +     H  PT S       G +  T+   + +   TY   
Sbjct: 3124 TLSTTPVDT---STP---VTTSTEAHSSPTTSE------GTSMPTSTPSEGSTPLTYMPV 3171

Query: 131  GQPYGISSYGALWAGIKTEGGLSQSQSPGQT-GFLSYGTSF--STPQPGQAPYSYQMQGS 187
                 +SS  +  +    +     + S   T    + GTS   STP  G  P +     +
Sbjct: 3172 STMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSN 3231

Query: 188  SFTTSSGI-------YTGNNSLTNSSGFNSS--QQDYPSYPSFGQGQYAQYYNSSPYPAH 238
            +   SS            N  LT S+  +SS    +  S P+    + +    S P    
Sbjct: 3232 TPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTT 3291

Query: 239  YMTSSNTS-----PTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSP-------STP 286
             + SS TS     P   ST  T   Q   S   +   + PT+ YS   +P       +TP
Sbjct: 3292 TVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTP 3351

Query: 287  IKDSDSDRL 295
            +  S++  L
Sbjct: 3352 VVSSEASTL 3360



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 72/362 (19%), Positives = 131/362 (36%), Gaps = 72/362 (19%)

Query: 6    LTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSET------------- 52
            ++S  S LS +    S P   ++  +S+  T  GT + T P S   T             
Sbjct: 1114 VSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVV 1173

Query: 53   ---ASTTADGSLNNFSGSAIGSSSFSPRPTHQF-SPPQIYPSNRPYP------HILPTPS 102
               A+T +   +++ +  A  + + SP PT +  S P   P  R  P         P  S
Sbjct: 1174 SSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVAS 1233

Query: 103  SQ-----TMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGA---------------- 141
            S+     T      T  TT  + +++  T      P   +S G+                
Sbjct: 1234 SEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSP 1293

Query: 142  -----LWAGIKTEGGLSQSQSPGQTGFLSYGTSF--STPQPGQAPYSYQMQGSSFTTSSG 194
                 L   + T+G +  S     +   + GTS   ST   G+ P +     ++   SS 
Sbjct: 1294 EASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSA 1353

Query: 195  IYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSS--------------PYPAHYM 240
            I   + +  ++S   ++  +  S P+  +G      N S              P  +   
Sbjct: 1354 ISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEA 1413

Query: 241  TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSP-------STPIKDSDSD 293
            ++ + +P   ST  T   +   S  T++ ++ PT+  S   +P       +TP+ +S++ 
Sbjct: 1414 STLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEAS 1473

Query: 294  RL 295
             L
Sbjct: 1474 TL 1475



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 58/281 (20%), Positives = 107/281 (38%), Gaps = 47/281 (16%)

Query: 25   LGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSP 84
            + +S INS S TP  T       S + ++ TTADG+    S  + GS+  +  P    S 
Sbjct: 1526 VASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPV---ST 1582

Query: 85   PQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWA 144
              +  S        P  S   + A  +   +T  + ++   + P  G P  ++S      
Sbjct: 1583 MLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPL-LTSIPVSTT 1641

Query: 145  GIKTEGGLSQSQSP--GQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYT-GNNS 201
             + +    + S +P    +  ++     S+P P         +G+S  TS+  YT G   
Sbjct: 1642 PVASPEASTLSTTPVDSNSPVITSTEVSSSPTPA--------EGTSMPTST--YTEGRTP 1691

Query: 202  LTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEP 261
            LT+ +                         ++P  +  +++ +T+P   ST  T   +  
Sbjct: 1692 LTSIT-----------------------VRTTPVASSAISTLSTTPVDNSTPVTTSTEAR 1728

Query: 262  PSGITSQAVTDP-------TAEYSTIHSPSTPIKDSDSDRL 295
             S  TS+  + P       T   ++I   +TP+  S++  L
Sbjct: 1729 SSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTL 1769



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 60/301 (19%), Positives = 117/301 (38%), Gaps = 32/301 (10%)

Query: 27   NSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRP-------T 79
            +S I++ S TP  T       + + ++ TT++G+    S  + GS+  +  P       +
Sbjct: 3119 SSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVS 3178

Query: 80   HQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFT-TGMQQATAYATYPQPGQPYGISS 138
             + S     P +   P    T ++ +  A G +  T T  +  T   + P    P   S 
Sbjct: 3179 SEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSE 3238

Query: 139  YGAL-WAGIKTEGGLSQSQSPGQTGFLSYGTSF--STPQPGQAPYSYQMQGSSFTTSSGI 195
               L    + +   L+ S     +   + GTS   STP  G  P +     ++   SS  
Sbjct: 3239 ASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSET 3298

Query: 196  YTGNNSLTNSSGFNSSQQDYPSYPSFGQGQ------YAQ--------YYNSSPYPAHYMT 241
             T + +  ++S   ++     S P    G       Y++         ++++P  +   +
Sbjct: 3299 STLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEAS 3358

Query: 242  SSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSP-------STPIKDSDSDR 294
            + +T+P   ST  T   +   S  T++  + PT+  S   +P       +TP+  S+ + 
Sbjct: 3359 TLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNT 3418

Query: 295  L 295
            L
Sbjct: 3419 L 3419



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 60/297 (20%), Positives = 102/297 (34%), Gaps = 23/297 (7%)

Query: 6    LTSPH-SRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNF 64
            +TSP  S L  +     GP + ++ ++S+     GT + T   S   T  T+   +    
Sbjct: 1290 VTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLV 1349

Query: 65   SGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAY 124
            + SAI  S  S  P    +P               +P++    +   +  + G    T+ 
Sbjct: 1350 ASSAI--SILSTTPVDNSTPV------TTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSI 1401

Query: 125  ATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPY---- 180
                 P      S+  A      T G  S   +   T         STP  G+ P     
Sbjct: 1402 PVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIP 1461

Query: 181  ---SYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYP------SYPSFGQGQYAQY-Y 230
               +      + T S+     N+ +  S+  +SS           S PS G         
Sbjct: 1462 VSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPV 1521

Query: 231  NSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287
            +++   +  + S +T+P   ST  T   Q   S  T+   +  T+ YS   +P T +
Sbjct: 1522 STTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSL 1578



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 65/292 (22%), Positives = 102/292 (34%), Gaps = 37/292 (12%)

Query: 25   LGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRP---THQ 81
            + +S IN+ S T   T       S + ++ TTADG+       + GS+  +  P   T  
Sbjct: 1938 VASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLV 1997

Query: 82   FSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQAT-AYATYPQPGQPYGISSYG 140
             S      S  P     P  +S   ++   T   T +Q +T +  T P  G P   +   
Sbjct: 1998 VSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLV- 2056

Query: 141  ALWAGIKTEGGLSQS---QSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYT 197
                 + +EG    +    S  Q    +  +S +T +      S   +GS   TS  + T
Sbjct: 2057 -----VSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLST 2111

Query: 198  --------GNNSLT----NSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSS-- 243
                       S T    NS    S++      P+ G       Y+    P   M  S  
Sbjct: 2112 TPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTT 2171

Query: 244  ----------NTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPST 285
                      +T+P   ST  T   +   S  TS+  + PT+  S   +P T
Sbjct: 2172 VVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFT 2223



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 61/301 (20%), Positives = 112/301 (37%), Gaps = 36/301 (11%)

Query: 11   SRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSE--TASTT-ADGSLNNFSGS 67
            + +S S+ S  G  +  S  +  S       V T+P++SSE  T STT  D S+   + +
Sbjct: 2550 TEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTST 2609

Query: 68   AIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATY 127
               SS  + + T               P   P+  S ++ +   +       +A+  +T 
Sbjct: 2610 ETSSSPTTAKDTSM-------------PISTPSEVSTSLTSILVSTMPVASSEASTLSTT 2656

Query: 128  PQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQ-----TGFLSYGTSFSTPQPGQAPYSY 182
            P   +    +S G   +    EG    + +PG+     T  L   T  +  +      + 
Sbjct: 2657 PVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTP 2716

Query: 183  QMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSS-PYPAHYMT 241
                +  TTS+     ++S T + G +       S PS G         S+ P  +   +
Sbjct: 2717 VDTSTPVTTSA---EASSSPTTAEGTSMR----ISTPSDGSTPLTSILVSTLPVASSEAS 2769

Query: 242  SSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSP-------STPIKDSDSDR 294
            + +T+    S   T   +   S  T++  + PT+  S   +P        TP+  S++  
Sbjct: 2770 TVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGT 2829

Query: 295  L 295
            L
Sbjct: 2830 L 2830



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 59/285 (20%), Positives = 105/285 (36%), Gaps = 24/285 (8%)

Query: 21  SGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTH 80
           + P++ +   +  S TP  +  +  P  S  T+ +T+D +    S +   SS  +P  T 
Sbjct: 87  TNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGT- 145

Query: 81  QFSPPQIYPSNRPYPHILPTPSSQTMAAY-GQTQFTTGMQQATAYATYPQPGQPYGISSY 139
               P   PS       +   S+  + ++   T  T  +  +T   T  Q          
Sbjct: 146 --DVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPES 203

Query: 140 GALWAGIKTEGGLSQSQSPGQTGFLSYG---TSFSTPQPGQAPYSYQMQGSSFTTSSGIY 196
             +     +EG    +  P  T  ++     T  +TP     P +   Q SS  T++   
Sbjct: 204 TTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTA--- 260

Query: 197 TGNNSLTNS--SGFNSSQQDYPSYPSFGQGQYAQYYNSSP----YPAHYMTSSNTSPTTP 250
               SL+NS  SG ++     P          A   +++P     P    T +++SPTT 
Sbjct: 261 -EGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTA 319

Query: 251 S-----TNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDS 290
                 T+   +   P +   +  +   T+E ST+    TP+  S
Sbjct: 320 EGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTL--SITPVDTS 362



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 65/300 (21%), Positives = 108/300 (36%), Gaps = 37/300 (12%)

Query: 21   SGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTH 80
            S P + ++ ++S+ +TP GT +     S   T  TT   S    + S  GS+  +P    
Sbjct: 3663 STPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSE-GSTLSTPSVVT 3721

Query: 81   QFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYG 140
                     +      +  T  S +M     T  TT +   T    +P+   P   S Y 
Sbjct: 3722 STPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYT 3781

Query: 141  ALWAGIKTEGGLSQSQSPGQTGFLSYGTS-------------FSTPQPGQAPYSYQMQGS 187
            ++     +EG  S +   G T      TS              S   P +A       G 
Sbjct: 3782 SMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGD 3841

Query: 188  SFT-----TSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTS 242
            + T     T +G ++    +T      +S++  P               S+  P  +  +
Sbjct: 3842 TSTPLLTSTKAGSFSIPAEVTTIRISITSERSTP---------LTTLLVSTTLPTSFPGA 3892

Query: 243  S-------NTSPT-TPSTNATYQLQEP-PSGITSQAVTDPTAEYSTIHSPSTPIKDSDSD 293
            S       +TS T TPST+       P  + I+   +T+ +   +TI  PSTP+  S +D
Sbjct: 3893 SIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTAD 3952



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 74/366 (20%), Positives = 124/366 (33%), Gaps = 61/366 (16%)

Query: 3    MQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLN 62
            M   T    R   +S   S   +  S I++ S TP  T       + + ++ TT++G+  
Sbjct: 855  MPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM 914

Query: 63   NFSGSAIGS-------------------------------------SSFSPRPTHQFSPP 85
              S    GS                                     ++ SP      S P
Sbjct: 915  PTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 974

Query: 86   QIYPSNRPYPHILPTPSSQTMAAYGQ--TQFTTGMQQATAYATYPQPGQPYGISSYGALW 143
               PS    P +  TP S T+ A  +  T  TT +   T   T  +   P   +   ++ 
Sbjct: 975  TSTPSEGTTP-LTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMP 1033

Query: 144  AGIKTEGGLSQSQSPGQTGFLS---YGTSFSTPQPGQAPY-SYQMQGSSFTTSSGIYTGN 199
                +EG    ++ P  T  ++     T  +TP     P  +Y    SS TT+ G  T  
Sbjct: 1034 TSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADG--TSM 1091

Query: 200  NSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSP----YPAHYMTSSNTSPTTPSTNAT 255
             + T S G ++     P          A   +++P     P    T +++SPTT     T
Sbjct: 1092 PTSTYSEG-STPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTT--AEGT 1148

Query: 256  YQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSP 315
                 PPS  T+   + P +    + S +  +  +  D   + +              SP
Sbjct: 1149 SIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEAS--------SP 1200

Query: 316  PPDSDL 321
            PP +++
Sbjct: 1201 PPTAEV 1206



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 68/281 (24%), Positives = 105/281 (37%), Gaps = 57/281 (20%)

Query: 16   SSESPSGPKLGNSHINSNSMTPNGTE------VKTEPMSSSETASTTADGSLNNFSGSAI 69
            S+E+ S P         NS    GT       V T P+ SSE ++ +A     +   +  
Sbjct: 1724 STEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTS 1783

Query: 70   GSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQ 129
              ++ SP      S P    S    P +  TP S T+ A  +         A+  +T P 
Sbjct: 1784 TEATSSPTTAEGTSIPTSTLSEGMTP-LTSTPVSHTLVANSE---------ASTLSTTPV 1833

Query: 130  PGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSF 189
                          + + T   +S S +P +      GTS +T  P +        GS+ 
Sbjct: 1834 DSN-----------SPVVTSTAVSSSPTPAE------GTSIATSTPSE--------GSTA 1868

Query: 190  TTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTT 249
             TS  + T     T +S   ++    P+  S     YAQ  +SSP  A     S+   +T
Sbjct: 1869 LTSIPVST----TTVASSETNTLSTTPAVTSTPVTTYAQV-SSSPTTAD---GSSMPTST 1920

Query: 250  PSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDS 290
            P          PP  +TS  V+  T   S I++ ST + D+
Sbjct: 1921 PREG------RPP--LTSIPVSTTTVASSEINTLSTTLADT 1953



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 58/268 (21%), Positives = 96/268 (35%), Gaps = 24/268 (8%)

Query: 19   SPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRP 78
            SP    L  + ++SNS     TEV + P  +  T+  T     + ++      +S + R 
Sbjct: 1645 SPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPT-----STYTEGRTPLTSITVRT 1699

Query: 79   THQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQAT-AYATYPQPGQPYGIS 137
            T   S      S  P  +  P  +S    +   T   T M  +T +  T P    P  +S
Sbjct: 1700 TPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIP--VS 1757

Query: 138  SYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYT 197
            +   L +   T        S   T      +S +T +    P S   +G +  TS+ +  
Sbjct: 1758 TTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPV-- 1815

Query: 198  GNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQ 257
             +  + NS     S     S              +SP       SS+ +P   ++ AT  
Sbjct: 1816 SHTLVANSEASTLSTTPVDS--------------NSPVVTSTAVSSSPTPAEGTSIATST 1861

Query: 258  LQEPPSGITSQAVTDPTAEYSTIHSPST 285
              E  + +TS  V+  T   S  ++ ST
Sbjct: 1862 PSEGSTALTSIPVSTTTVASSETNTLST 1889



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 53/288 (18%), Positives = 109/288 (37%), Gaps = 21/288 (7%)

Query: 5   DLTSPHSRLSGSSESPS---GPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSL 61
           ++++P +  + +S SP+   GP L NS  +  S       +    + SSE ++ +   + 
Sbjct: 242 EISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAA 301

Query: 62  NNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQ--TQFTTGMQ 119
            N        +S SP      S P    +    P +  TP+S    A  +  T   T + 
Sbjct: 302 TNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTP-LTSTPASTMPVATSEMSTLSITPVD 360

Query: 120 QATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAP 179
            +T   T  +P      +   ++     +EG    +  P  T  ++   + +T       
Sbjct: 361 TSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTS------ 414

Query: 180 YSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHY 239
            +  +   +F T++   + + +    +   +S     S P       +   +++P  +  
Sbjct: 415 -TIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTP-----LTSMPVSTTPVASSE 468

Query: 240 MTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287
            ++ +T+P    T  T   +   S  T++  + PT   ST    STP+
Sbjct: 469 ASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPT---STPSEGSTPL 513



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 74/336 (22%), Positives = 127/336 (37%), Gaps = 58/336 (17%)

Query: 5    DLTSPHSRLSGSSESPS---GPKLGNSHINSNSMTPNGTEVKTEPMSSSE--TASTTADG 59
            D ++P +  + +S SP+   G  +  S  +  S       V T P++SSE  T STT   
Sbjct: 2836 DTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVD 2895

Query: 60   SLNNFSGSAIGSSSFSPRPTHQFSPPQIYPS--NRPYPHIL----PTPSSQ-----TMAA 108
            +    + S  GSS  SP      S P   PS  + P   IL    P   S+     T   
Sbjct: 2896 TSIPVTTSTEGSS--SPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPV 2953

Query: 109  YGQTQFTTGMQQATAYATYPQPGQPYG--------ISSYGALWAGIKTEGGLSQSQSPGQ 160
              +T  TT  + +++  T      P          ++S       + +    + S++P  
Sbjct: 2954 DTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPAD 3013

Query: 161  TGFLSYGTSFSTPQPGQA-----PYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDY 215
            T      ++ ++  P  A     P S   +GS+  TS  + T   ++  +S  +++  D 
Sbjct: 3014 TSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDS 3073

Query: 216  PS------------YPSFGQGQYAQYY------------NSSPYPAHYMTSSNTSPTTPS 251
             S             P+ G       Y            +++P  +  +++ +T+P   S
Sbjct: 3074 NSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTS 3133

Query: 252  TNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287
            T  T   +   S  TS+  + PT   ST    STP+
Sbjct: 3134 TPVTTSTEAHSSPTTSEGTSMPT---STPSEGSTPL 3166



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 70/295 (23%), Positives = 109/295 (36%), Gaps = 53/295 (17%)

Query: 8    SPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLN---NF 64
            S  S LS      S P L ++   S S+    T ++    S   T  TT   S     +F
Sbjct: 3830 SEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSF 3889

Query: 65   SGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAY 124
             G++I S+      T  F+P     S    P  + T  S ++   G T  TT    +T  
Sbjct: 3890 PGASIASTPPLDTST-TFTPSTDTASTPTIP--VATTISVSVITEGSTPGTTIFIPSTPV 3946

Query: 125  ATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTS--FSTP-QPGQAPYS 181
             +      P   ++ GA+   + T   L+   +   +   S+ T+  F+TP     AP +
Sbjct: 3947 TSSTADVFP---ATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLT 4003

Query: 182  YQMQGSS----FTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPA 237
            Y    ++     TTS G  T  ++L+ +S                               
Sbjct: 4004 YVTMSTAPSTPRTTSRGCTTSASTLSATS-----------------------------TP 4034

Query: 238  HYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDS 292
            H  TS  T P TPS+ ++      PS ITS  +  PT  +   HS + P   + S
Sbjct: 4035 HTSTSVTTRPVTPSSESS-----RPSTITSHTI-PPT--FPPAHSSTPPTTSASS 4081



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 61/287 (21%), Positives = 104/287 (36%), Gaps = 25/287 (8%)

Query: 11   SRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIG 70
            S LS +    + P + ++ ++S+     GT + T   +   T  T+        + SAI 
Sbjct: 1649 STLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAIS 1708

Query: 71   SSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQP 130
            + S +P             ++ P        SS T +       +T  +  T   + P  
Sbjct: 1709 TLSTTP-----------VDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVS 1757

Query: 131  GQPYGISSYGALWA-GIKTEGGLSQSQSPGQTGFLSYGTSF--STPQPGQAPYSYQMQGS 187
              P   S    L A  I T   ++ S     +   + GTS   ST   G  P +      
Sbjct: 1758 TTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSH 1817

Query: 188  SFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYP-AHYMTSSNTS 246
            +   +S   T + +  +S+    +     S P+  +G       S+P   +  +TS   S
Sbjct: 1818 TLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEG--TSIATSTPSEGSTALTSIPVS 1875

Query: 247  PTTPSTNATYQLQEPPSGITSQAVT-------DPTAEYSTIHSPSTP 286
             TT +++ T  L   P+ +TS  VT        PT    +    STP
Sbjct: 1876 TTTVASSETNTLSTTPA-VTSTPVTTYAQVSSSPTTADGSSMPTSTP 1921



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 66/308 (21%), Positives = 107/308 (34%), Gaps = 23/308 (7%)

Query: 3    MQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLN 62
            M  ++S  S  S +    S P   ++  +S+  T  GT + T P S   T   +   S  
Sbjct: 2407 MPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTT 2466

Query: 63   NFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQAT 122
                S  G+ S +P  T           + P        SS T A       +T  + +T
Sbjct: 2467 PVVSSEAGTLSTTPVDT-----------STPMTTSTEASSSPTTAEDIVVPISTASEGST 2515

Query: 123  AYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSY 182
               + P    P        L            S SP  T      +S ++ +    P S 
Sbjct: 2516 LLTSIPVSTTPVASPEASTL------STTPVDSNSPVVTS-TEISSSATSAEGTSMPTST 2568

Query: 183  QMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTS 242
              +GS+   S  + T   + + +S  +++  D  S P     +     +SSP  A   + 
Sbjct: 2569 YSEGSTPLRSMPVSTKPLASSEASTLSTTPVD-TSIPVTTSTE----TSSSPTTAKDTSM 2623

Query: 243  SNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGK 302
              ++P+  ST+ T  L       +S+A T  T    T    +T    S S     GS   
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMP 2683

Query: 303  SRGRGRRN 310
            +   G R+
Sbjct: 2684 TSTPGERS 2691


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 77/285 (27%), Positives = 108/285 (37%), Gaps = 63/285 (22%)

Query: 2    EMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSL 61
            +M    S HS  +G+   P+  K   S   +  MT          +++S T+ T +  S 
Sbjct: 2031 QMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMT----------VTTSGTSQTHSSFST 2080

Query: 62   NNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQA 121
               S S I SSS+ P+  +  S P   P     PH+    SS T      T  +T  Q +
Sbjct: 2081 ATASSSFISSSSWLPQ--NSSSRPPSSPITTQLPHL----SSAT------TPVSTTNQLS 2128

Query: 122  TAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYS 181
            ++++  P P  P  +SSY            +  S S  QT   S GTS            
Sbjct: 2129 SSFS--PSPSAPSTVSSY------------VPSSHSSPQTSSPSVGTS------------ 2162

Query: 182  YQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMT 241
                      SS +    +S T SSG +SS   +P+  S      +  + SS  PA   T
Sbjct: 2163 ----------SSFVSAPVHSTTLSSGSHSSLSTHPTTASVSA---SPLFPSS--PAASTT 2207

Query: 242  SSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTP 286
               T P T S+  T     P S +T           STI  PSTP
Sbjct: 2208 IRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTP 2252



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 72/314 (22%), Positives = 123/314 (39%), Gaps = 48/314 (15%)

Query: 2    EMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTA---- 57
            +M    S HS  +G+   P+  K   S   +  MTP  +     P S S   ++T+    
Sbjct: 1862 QMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYH 1921

Query: 58   DGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQF-TT 116
              S ++   +   +++ +P+ T   +   +  +       LPTP +      G + F +T
Sbjct: 1922 TSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSST 1981

Query: 117  GMQQATAY---ATYPQPGQPY------------GISSYGALWAGIKTEGGLSQSQS---- 157
            G   AT++    TYP P  P              + +       I T   ++ S S    
Sbjct: 1982 GPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHST 2041

Query: 158  -----PGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSS-GIYTGNNSLTNSSGF--- 208
                 P  T   + G++ + P     P +    G+S T SS    T ++S  +SS +   
Sbjct: 2042 PTGTVPPPTTLKATGSTHTAP-----PMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQ 2096

Query: 209  NSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSS-NTSPTTPSTNATY--------QLQ 259
            NSS +  PS P   Q  +     +     + ++SS + SP+ PST ++Y        Q  
Sbjct: 2097 NSSSRP-PSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTS 2155

Query: 260  EPPSGITSQAVTDP 273
             P  G +S  V+ P
Sbjct: 2156 SPSVGTSSSFVSAP 2169



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 69/298 (23%), Positives = 107/298 (35%), Gaps = 35/298 (11%)

Query: 7    TSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTE-PMSSSETASTTADGSLNNFS 65
            TS HS  S +      P       ++ ++TPN T  +T  P++ + +A+++         
Sbjct: 1523 TSLHSHTSSTHHPEVTPT------STTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTH 1576

Query: 66   GSAIGSSSFS---PRPTHQFSPPQIYPSNR-----------PYPHILPTPSSQTMAAYGQ 111
                GSS FS   P     F     YP+             P+   L TPS+ T+     
Sbjct: 1577 SPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTH 1636

Query: 112  TQFTTGMQ-QATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSF 170
             Q  T     +    T P P       S         T  G SQ+ S   T      TS 
Sbjct: 1637 AQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTA----KTST 1692

Query: 171  STPQPGQAPYSYQMQGSSFT--TSSGIYTGNNSLT-NSSGFNSSQQDYPSYPSFGQGQYA 227
            S      + +  +   +S T  T +   TG   +T  +SG + S+       SF   + +
Sbjct: 1693 SLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRS------SFSTAKTS 1746

Query: 228  QYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPST 285
               +S     H+   ++TS T+ + N T      P   T+ A +       T HSP T
Sbjct: 1747 TSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPT 1804



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 66/295 (22%), Positives = 102/295 (34%), Gaps = 30/295 (10%)

Query: 6    LTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFS 65
            +T   +R + S+ SP+      S   +    P      T P         T   S N   
Sbjct: 1301 VTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSP---------TLPKSTNQEL 1351

Query: 66   GSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYA 125
                 + +  PRPT   +     P  +P     PT +++T      T++TT     T ++
Sbjct: 1352 PGTTATQTTGPRPTPASTTGPTTP--QPGQPTRPT-ATETTQTRTTTEYTTPQTPHTTHS 1408

Query: 126  TYPQPGQPYGISSYGALWA----GIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQA--P 179
              P  G P  + S G + A       T    S  ++   T    + TS  TP       P
Sbjct: 1409 P-PTAGSP--VPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITP 1465

Query: 180  YSYQM--QGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPA 237
               QM    S+ +  +G      +L  +   +++    P+     Q   +   N +P   
Sbjct: 1466 THAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSL 1525

Query: 238  HYMTSSN-------TSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPST 285
            H  TSS        TS TT + N T      P   T+ A +       T HSP T
Sbjct: 1526 HSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPT 1580


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,358,688
Number of Sequences: 37866
Number of extensions: 1298584
Number of successful extensions: 6264
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 293
Number of HSP's that attempted gapping in prelim test: 4887
Number of HSP's gapped (non-prelim): 1179
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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