Search of human proteins with 19913414

Search of human proteins with 19913414

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19913414 adaptor-related protein complex 2, alpha 1 subunit
isoform 1 [Homo sapiens]
         (977 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19913414 adaptor-related protein complex 2, alpha 1 subunit i...  1929   0.0  
gi|19913416 adaptor-related protein complex 2, alpha 1 subunit i...  1873   0.0  
gi|27477041 adaptor-related protein complex 2, alpha 2 subunit [...  1529   0.0  
gi|71772942 adaptor-related protein complex 1, gamma 1 subunit i...   278   1e-74
gi|71773010 adaptor-related protein complex 1, gamma 1 subunit i...   274   3e-73
gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [H...   262   1e-69
gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit...   169   2e-41
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ...   137   6e-32
gi|22027653 adaptor-related protein complex 1 beta 1 subunit iso...    97   7e-20
gi|22027651 adaptor-related protein complex 1 beta 1 subunit iso...    95   3e-19
gi|4557469 adaptor-related protein complex 2, beta 1 subunit iso...    91   5e-18
gi|71773106 adaptor-related protein complex 2, beta 1 subunit is...    89   3e-17
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ...    68   5e-11
gi|22547195 sterol regulatory element binding transcription fact...    49   2e-05
gi|52630419 sterol regulatory element binding transcription fact...    49   3e-05
gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo ...    48   4e-05
gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo ...    48   4e-05
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              48   5e-05
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]              47   7e-05
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]              47   7e-05
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]              47   7e-05
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]              47   7e-05
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]              47   7e-05
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]              47   7e-05
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 47   9e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             46   2e-04
gi|33356148 formin-like 1 [Homo sapiens]                               46   2e-04
gi|153792074 proline rich 12 [Homo sapiens]                            46   2e-04
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    45   3e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    44   6e-04

>gi|19913414 adaptor-related protein complex 2, alpha 1 subunit
           isoform 1 [Homo sapiens]
          Length = 977

 Score = 1929 bits (4998), Expect = 0.0
 Identities = 977/977 (100%), Positives = 977/977 (100%)

Query: 1   MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60
           MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
Sbjct: 1   MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60

Query: 61  KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120
           KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
Sbjct: 61  KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120

Query: 121 ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP 180
           ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP
Sbjct: 121 ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP 180

Query: 181 DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSA 240
           DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSA
Sbjct: 181 DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSA 240

Query: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV 300
           STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV
Sbjct: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV 300

Query: 301 QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE 360
           QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE
Sbjct: 301 QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE 360

Query: 361 FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI 420
           FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI
Sbjct: 361 FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI 420

Query: 421 REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA 480
           REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA
Sbjct: 421 REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA 480

Query: 481 KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL 540
           KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL
Sbjct: 481 KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL 540

Query: 541 LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE 600
           LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE
Sbjct: 541 LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE 600

Query: 601 EMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADL 660
           EMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADL
Sbjct: 601 EMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADL 660

Query: 661 LGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLA 720
           LGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLA
Sbjct: 661 LGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLA 720

Query: 721 DPAPAADPGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFY 780
           DPAPAADPGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFY
Sbjct: 721 DPAPAADPGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFY 780

Query: 781 GNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLL 840
           GNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLL
Sbjct: 781 GNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLL 840

Query: 841 SVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMD 900
           SVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMD
Sbjct: 841 SVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMD 900

Query: 901 AEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRT 960
           AEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRT
Sbjct: 901 AEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRT 960

Query: 961 SKEPVSRHLCELLAQQF 977
           SKEPVSRHLCELLAQQF
Sbjct: 961 SKEPVSRHLCELLAQQF 977


>gi|19913416 adaptor-related protein complex 2, alpha 1 subunit
           isoform 2 [Homo sapiens]
          Length = 955

 Score = 1873 bits (4851), Expect = 0.0
 Identities = 955/977 (97%), Positives = 955/977 (97%), Gaps = 22/977 (2%)

Query: 1   MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60
           MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
Sbjct: 1   MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60

Query: 61  KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120
           KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
Sbjct: 61  KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120

Query: 121 ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP 180
           ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP
Sbjct: 121 ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP 180

Query: 181 DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSA 240
           DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSA
Sbjct: 181 DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSA 240

Query: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV 300
           STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV
Sbjct: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV 300

Query: 301 QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE 360
           QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE
Sbjct: 301 QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE 360

Query: 361 FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI 420
           FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI
Sbjct: 361 FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI 420

Query: 421 REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA 480
           REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA
Sbjct: 421 REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA 480

Query: 481 KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL 540
           KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL
Sbjct: 481 KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL 540

Query: 541 LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE 600
           LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE
Sbjct: 541 LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE 600

Query: 601 EMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADL 660
           EMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADL
Sbjct: 601 EMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADL 660

Query: 661 LGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLA 720
           LGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLS               
Sbjct: 661 LGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLS--------------- 705

Query: 721 DPAPAADPGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFY 780
                  PGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFY
Sbjct: 706 -------PGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFY 758

Query: 781 GNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLL 840
           GNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLL
Sbjct: 759 GNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLL 818

Query: 841 SVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMD 900
           SVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMD
Sbjct: 819 SVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMD 878

Query: 901 AEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRT 960
           AEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRT
Sbjct: 879 AEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRT 938

Query: 961 SKEPVSRHLCELLAQQF 977
           SKEPVSRHLCELLAQQF
Sbjct: 939 SKEPVSRHLCELLAQQF 955


>gi|27477041 adaptor-related protein complex 2, alpha 2 subunit
           [Homo sapiens]
          Length = 939

 Score = 1530 bits (3960), Expect = 0.0
 Identities = 784/981 (79%), Positives = 852/981 (86%), Gaps = 46/981 (4%)

Query: 1   MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60
           MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
Sbjct: 1   MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60

Query: 61  KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120
           KLLFIFLLGHDIDFGHMEAVNLLSSN+YTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
Sbjct: 61  KLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120

Query: 121 ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP 180
           ASRNPTFM LALHCIA+VGSREM EAFA +IP++LVAGD+MDSVKQSAALCLLRLY+ SP
Sbjct: 121 ASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSP 180

Query: 181 DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSA 240
           DLVPMG+WT+RVVHLLNDQH+GVVTAA SLIT L +KNP++FKT VSLAVSRLSRIV+SA
Sbjct: 181 DLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSA 240

Query: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV 300
           STDLQDYTYYFVPAPWLSVKLLRLLQCYPPP D AV+GRL ECLET+LNKAQEPPKSKKV
Sbjct: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPP-DPAVRGRLTECLETILNKAQEPPKSKKV 299

Query: 301 QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE 360
           QHSNAKNA+LFE ISLIIH+DSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE
Sbjct: 300 QHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE 359

Query: 361 FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI 420
           FSHEAVKTHI+TVINALKTERDVSVRQRA DLLYAMCDRSNA QIV+EML YLETADY+I
Sbjct: 360 FSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSI 419

Query: 421 REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA 480
           REEIVLKVAILAEKYAVDY+WYVDTILNLIRIAGDYVSEEVWYRV+QIV NRDDVQGYAA
Sbjct: 420 REEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAA 479

Query: 481 KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL 540
           KTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP +QF LLHSKFHLCSV TRAL
Sbjct: 480 KTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRAL 539

Query: 541 LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE 600
           LLSTYIKF+NLFPE K TIQ VLR+ SQLRNADVELQQRAVEYL LS+VASTD+LATVLE
Sbjct: 540 LLSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLE 599

Query: 601 EMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTP---STVSTPSPS 657
           EMPPFPERESSILAKLK+KKGP   + L+D +RD  S D+NGG EP P   S VSTPSPS
Sbjct: 600 EMPPFPERESSILAKLKKKKGPSTVTDLEDTKRD-RSVDVNGGPEPAPASTSAVSTPSPS 658

Query: 658 ADLLGLRAAPP-PAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPM 716
           ADLLGL AAPP PA PP S+G   LLVDVF   A+                         
Sbjct: 659 ADLLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASV------------------------ 694

Query: 717 ALLADPAPAADPGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRM 776
                           + P  P +++   +FVCKNNGVLFENQLLQIG+KSEFRQNLGRM
Sbjct: 695 ----------------VAPLAPGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRM 738

Query: 777 YLFYGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLT 836
           ++FYGNKTS QF NF+PT++   DLQ  L +QTK V   V+GGAQVQQV+NIEC+ DF  
Sbjct: 739 FIFYGNKTSTQFLNFTPTLICSDDLQPNLNLQTKPVDPTVEGGAQVQQVVNIECVSDFTE 798

Query: 837 PPLLSVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKAN 896
            P+L+++FRYGG  Q ++++LP+T+NKFFQPTEMA+QDFFQRWKQLS PQQE Q IFKA 
Sbjct: 799 APVLNIQFRYGGTFQNVSVQLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQNIFKAK 858

Query: 897 HPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRL 956
           HPMD EVTKAK++GFGSALL+ VDPNP NFVGAGII TK  Q+GCLLRLEPN QAQMYRL
Sbjct: 859 HPMDTEVTKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRL 918

Query: 957 TLRTSKEPVSRHLCELLAQQF 977
           TLRTSKE VS+ LCELL+ QF
Sbjct: 919 TLRTSKEAVSQRLCELLSAQF 939


>gi|71772942 adaptor-related protein complex 1, gamma 1 subunit
           isoform b [Homo sapiens]
          Length = 822

 Score =  278 bits (712), Expect = 1e-74
 Identities = 211/714 (29%), Positives = 372/714 (52%), Gaps = 58/714 (8%)

Query: 13  LAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDI 72
           L   I  IR  +++  E + I KE A IRS F+ +   D   + + V KLL++ +LG+  
Sbjct: 7   LRELIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPA 63

Query: 73  DFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLAL 132
            FG +E + L++S K+T+K+IGYL   +L++   ++  L+ N IKNDL         LAL
Sbjct: 64  HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123

Query: 133 HCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARV 192
             +  +GS EM    A ++ ++L   +S   +++ AALC + + +  P+L+ M  +    
Sbjct: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPAT 179

Query: 193 VHLLNDQHMGVVTAAVSLITCLCKKNPD---DFKTCVSLAVSRLSRIVSSASTDLQDYTY 249
            +LLN+++ GV+  +V L+T +C+++PD    F+  V   V  L  ++ S  +   D + 
Sbjct: 180 KNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSG 239

Query: 250 YFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAI 309
             +  P+L V++LRLL+     +D +      E +  +L +     ++ K    N  NAI
Sbjct: 240 --ISDPFLQVRILRLLRILGRNDDDSS-----EAMNDILAQVATNTETSK----NVGNAI 288

Query: 310 LFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTH 369
           L+ET+  I+   SE  L V A N LG+FL + + N+RY+AL S+  L + +  H AV+ H
Sbjct: 289 LYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSL--LKTVQTDHNAVQRH 346

Query: 370 IDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVA 429
             T+++ LK + DVS+++RA +L +A+ + +N + ++ E+L +L++ +   + +    + 
Sbjct: 347 RSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIF 405

Query: 430 ILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQA 489
           + AEKYA    W++DTI+ ++  AG YV ++    ++Q++TN  ++  Y  + +++A+  
Sbjct: 406 LAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILG 465

Query: 490 PACHENMVKVGGYILGEFGN-LIAGDPRSSPPVQ------FSLLHSKF--HLCSVATRAL 540
               + +V+V  + +GE+G+ L++G      P+Q        +L S    ++ +  TR  
Sbjct: 466 DYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGY 525

Query: 541 LLSTYIKFINLFPETKATIQGVLRA-GSQLRNADVELQQRAVEYLTLSSVASTDVLATVL 599
            L+  +K    F  T   I+ V+   GS +   DVELQQRAVEY  L       + + +L
Sbjct: 526 ALTAIMKLSTRFTCTVNRIKKVVSIYGSSI---DVELQQRAVEYNALFK-KYDHMRSALL 581

Query: 600 EEMPPFPERESSILAKLKRKKGPGAGSALD----DGRRDPSSN-----DINGGMEPTP-- 648
           E MP   +  ++   ++ +  G    + L+         P+S      D+ GG + TP  
Sbjct: 582 ERMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVI 641

Query: 649 STVSTPSPSA------DLLG---LRAAPPPAAPPASAGAGNLLVDVFDGPAAQP 693
            T  T  PS+      DLLG   L  AP  A  PAS    +    + DG ++QP
Sbjct: 642 PTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQP 695


>gi|71773010 adaptor-related protein complex 1, gamma 1 subunit
           isoform a [Homo sapiens]
          Length = 825

 Score =  274 bits (700), Expect = 3e-73
 Identities = 210/717 (29%), Positives = 371/717 (51%), Gaps = 61/717 (8%)

Query: 13  LAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDI 72
           L   I  IR  +++  E + I KE A IRS F+ +   D   + + V KLL++ +LG+  
Sbjct: 7   LRELIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPA 63

Query: 73  DFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLAL 132
            FG +E + L++S K+T+K+IGYL   +L++   ++  L+ N IKNDL         LAL
Sbjct: 64  HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123

Query: 133 HCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARV 192
             +  +GS EM    A ++ ++L   +S   +++ AALC + + +  P+L+ M  +    
Sbjct: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPAT 179

Query: 193 VHLLNDQHMGVVTAAVSLITCLCKKNPDDF------KTCVSLAVSRLSRIVSSASTDLQD 246
            +LLN+++ GV+  +V L+T +C+++PD        +  V   V  L  ++ S  +   D
Sbjct: 180 KNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHD 239

Query: 247 YTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAK 306
            +   +  P+L V++LRLL+     +D +      E +  +L +     ++ K    N  
Sbjct: 240 VSG--ISDPFLQVRILRLLRILGRNDDDSS-----EAMNDILAQVATNTETSK----NVG 288

Query: 307 NAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAV 366
           NAIL+ET+  I+   SE  L V A N LG+FL + + N+RY+AL S+  L + +  H AV
Sbjct: 289 NAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSL--LKTVQTDHNAV 346

Query: 367 KTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVL 426
           + H  T+++ LK + DVS+++RA +L +A+ + +N + ++ E+L +L++ +   + +   
Sbjct: 347 QRHRSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCAS 405

Query: 427 KVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEA 486
            + + AEKYA    W++DTI+ ++  AG YV ++    ++Q++TN  ++  Y  + +++A
Sbjct: 406 GIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKA 465

Query: 487 LQAPACHENMVKVGGYILGEFGN-LIAGDPRSSPPVQ------FSLLHSKF--HLCSVAT 537
           +      + +V+V  + +GE+G+ L++G      P+Q        +L S    ++ +  T
Sbjct: 466 ILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVT 525

Query: 538 RALLLSTYIKFINLFPETKATIQGVLRA-GSQLRNADVELQQRAVEYLTLSSVASTDVLA 596
           R   L+  +K    F  T   I+ V+   GS +   DVELQQRAVEY  L       + +
Sbjct: 526 RGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSI---DVELQQRAVEYNALFK-KYDHMRS 581

Query: 597 TVLEEMPPFPERESSILAKLKRKKGPGAGSALD----DGRRDPSSN-----DINGGMEPT 647
            +LE MP   +  ++   ++ +  G    + L+         P+S      D+ GG + T
Sbjct: 582 ALLERMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDIT 641

Query: 648 P--STVSTPSPSA------DLLG---LRAAPPPAAPPASAGAGNLLVDVFDGPAAQP 693
           P   T  T  PS+      DLLG   L  AP  A  PAS    +    + DG ++QP
Sbjct: 642 PVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQP 698


>gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [Homo
           sapiens]
          Length = 785

 Score =  262 bits (669), Expect = 1e-69
 Identities = 209/725 (28%), Positives = 355/725 (48%), Gaps = 63/725 (8%)

Query: 17  ISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGH 76
           I +IR  K++  E + I KE A+IR+ F+     D   + + + KLL++ +LG+   FG 
Sbjct: 12  IEEIRGAKTQAQEREVIQKECAHIRASFRDG---DPVHRHRQLAKLLYVHMLGYPAHFGQ 68

Query: 77  MEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIA 136
           ME + L++S+++T+K++GYL   +L++   +   LI N+IKNDL+        LAL  ++
Sbjct: 69  MECLKLIASSRFTDKRVGYLGAMLLLDERHDAHLLITNSIKNDLSQGIQPVQGLALCTLS 128

Query: 137 NVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLL 196
            +GS EM    A ++ ++L+       V++ A L  + + +  P+L  +  +      LL
Sbjct: 129 TMGSAEMCRDLAPEVEKLLLQPSPY--VRKKAILTAVHMIRKVPELSSV--FLPPCAQLL 184

Query: 197 NDQHMGVVTAAVSLITCLCKKNPD---DFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVP 253
           +++H G++   ++LIT LC+++P     F+  V   V  L  +V+   +   +++   V 
Sbjct: 185 HERHHGILLGTITLITELCERSPAALRHFRKVVPQLVHILRTLVTMGYST--EHSISGVS 242

Query: 254 APWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFET 313
            P+L V++LRLL+         + GR  E     +N       +      NA NA+LFET
Sbjct: 243 DPFLQVQILRLLR---------ILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFET 293

Query: 314 ISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTV 373
           +  I+   S   L V A N LG+FL + + N+RY+AL S+  L  S+  H AV+ H  TV
Sbjct: 294 VLTIMDIRSAAGLRVLAVNILGRFLLNSDRNIRYVALTSLLRLVQSD--HSAVQRHRPTV 351

Query: 374 INALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAE 433
           +  L+ E D S+ +RA +L  A+ + SN + ++ E+  +LE+    +R +    + + AE
Sbjct: 352 VECLR-ETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAE 410

Query: 434 KYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACH 493
           ++A    W++DTIL+++  AG +V ++    + Q++    ++  Y+ + ++ AL      
Sbjct: 411 RFAPTKRWHIDTILHVLTTAGTHVRDDAVANLTQLIGGAQELHAYSVRRLYNALAEDISQ 470

Query: 494 ENMVKVGGYILGEFGN-LIAGDPRSSPPVQ------FSLLHS--KFHLCSVATRALLLST 544
           + +V+V  + +GE+G+ L+AG+     P+Q       +LL    + H+   ATR   L+ 
Sbjct: 471 QPLVQVAAWCIGEYGDLLLAGNCEEIEPLQVDEEEVLALLEKVLQSHMSLPATRGYALTA 530

Query: 545 YIKF-INLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMP 603
            +K    L  +     Q V   GS L   DVELQQRAVEY TL       + A +LE+MP
Sbjct: 531 LMKLSTRLCGDNNRIRQVVSIYGSCL---DVELQQRAVEYDTLFR-KYDHMRAAILEKMP 586

Query: 604 PFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGL 663
                       L  + GP A     + +     ++      PT    S      DLL  
Sbjct: 587 ------------LVERDGPQADEEAKESKEAAQLSE--AAPVPTEPQASQLLDLLDLLDG 632

Query: 664 RAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPE---------EAFLSELEPPAPES 714
            +      P      G  LV + D P   P   P P+         +  LS + P  PE+
Sbjct: 633 ASGDVQHPPHLDPSPGGALVHLLDLPCVPPPPAPIPDLKVFEREGVQLNLSFIRP--PEN 690

Query: 715 PMALL 719
           P  LL
Sbjct: 691 PALLL 695


>gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit
           [Homo sapiens]
          Length = 1137

 Score =  169 bits (427), Expect = 2e-41
 Identities = 135/523 (25%), Positives = 247/523 (47%), Gaps = 35/523 (6%)

Query: 2   PAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCK 61
           PA +K      L   +  I    SK  E K I +EL+++++            K+  V +
Sbjct: 25  PAAAKASFSSRLGSLVRGITALTSKHEEEKLIQQELSSLKATVSAPTTTLKMMKECMV-R 83

Query: 62  LLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLA 121
           L++  +LG+D  FG++ A+ L       EK++GYL +S+ ++ + EL+ L+ N +  DL 
Sbjct: 84  LIYCEMLGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQ 143

Query: 122 SRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPD 181
           S N   +C+AL  ++ +   EM  A    I   L    S + V++ A L L + +  +P+
Sbjct: 144 STNLVEVCMALTVVSQIFPCEMIPAVLPLIEDKL--QHSKEIVRRKAVLALYKFHLIAPN 201

Query: 182 LVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSAS 241
            V       R    L D+ +GV+ A++ +   + K+N   +K      V+ L ++V    
Sbjct: 202 QVQHIHIKFR--KALCDRDVGVMAASLHIYLRMIKENSSGYKDLTGSFVTILKQVVGGKL 259

Query: 242 TDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQ 301
               ++ Y+ VPAPWL ++LLR+L      +D      + + L+  L +A+         
Sbjct: 260 P--VEFNYHSVPAPWLQIQLLRILGLL-GKDDQRTSELMYDVLDESLRRAE--------L 308

Query: 302 HSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEF 361
           + N   AILFE +  +     +  LL +A   +G+F+   + NL+YL L+++  +   + 
Sbjct: 309 NHNVTYAILFECVHTVYSIYPKSELLEKAAKCIGKFVLSPKINLKYLGLKALTYVIQQD- 367

Query: 362 SHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYL-ETADYAI 420
                  H  T+I  L    D  +++   +LLY + +  N   IV +ML YL ++ +  +
Sbjct: 368 -PTLALQHQMTIIECL-DHPDPIIKRETLELLYRITNAQNITVIVQKMLEYLHQSKEEYV 425

Query: 421 REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDD------ 474
              +V K+A LAEKYA D +W++ T+  +  + GD +  ++    L+++    D      
Sbjct: 426 IVNLVGKIAELAEKYAPDNAWFIQTMNAVFSVGGDVMHPDIPNNFLRLLAEGFDDETEDQ 485

Query: 475 ------VQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLI 511
                 VQ Y      E +  P   +  ++V  ++LGE+  L+
Sbjct: 486 QLRLYAVQSYLTLLDMENVFYP---QRFLQVMSWVLGEYSYLL 525


>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 1153

 Score =  137 bits (344), Expect = 6e-32
 Identities = 118/492 (23%), Positives = 235/492 (47%), Gaps = 55/492 (11%)

Query: 11  RGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGH 70
           + L   +  IRN   KE E K I++ +  I+ + K D       K   VCKL ++ +LG+
Sbjct: 16  KNLQDLVRGIRN--HKEDEAKYISQCIDEIKQELKQDNIA---VKANAVCKLTYLQMLGY 70

Query: 71  DIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCL 130
           DI +     + ++S++K+T K+IGYL  S   +  +++I L  N I+ DL+S +     +
Sbjct: 71  DISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQYDTGV 130

Query: 131 ALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTA 190
           AL  ++   + ++    A DI  ++    +   +++ A L + +++   P+   +     
Sbjct: 131 ALTGLSCFVTPDLARDLANDIMTLM--SHTKPYIRKKAVLIMYKVFLKYPE--SLRPAFP 186

Query: 191 RVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYY 250
           R+   L D   GV +AAV++I  L ++NP   K  +SLA      + SS +         
Sbjct: 187 RLKEKLEDPDPGVQSAAVNVICELARRNP---KNYLSLAPLFFKLMTSSTNN-------- 235

Query: 251 FVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAIL 310
                W+ +K+++L     P E    K +L+E L  ++             HS +  ++L
Sbjct: 236 -----WVLIKIIKLFGALTPLEPRLGK-KLIEPLTNLI-------------HSTSAMSLL 276

Query: 311 FETISLIIHY-----DSEPN--LLVRACNQ-LGQFLQHRETNLRYLALESMCTLASSEFS 362
           +E ++ +I          PN    ++ C Q L   ++  + NL+YL L +M  +  +   
Sbjct: 277 YECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTH-- 334

Query: 363 HEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETAD-YAIR 421
            ++V++H D ++  L  ++D S+R RA DLLY M  + N  +IV +++ +++ A+    R
Sbjct: 335 PKSVQSHKDLILQCL-DDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYR 393

Query: 422 EEIVLKVAILAE----KYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQG 477
           +E++ K+  +      +Y  ++ WY+  ++ L R+ G      +  ++L +      ++ 
Sbjct: 394 DELLTKIIDICSQSNYQYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRK 453

Query: 478 YAAKTVFEALQA 489
           +A   +   L +
Sbjct: 454 FAVSQMSALLDS 465


>gi|22027653 adaptor-related protein complex 1 beta 1 subunit
           isoform b [Homo sapiens]
          Length = 942

 Score = 97.1 bits (240), Expect = 7e-20
 Identities = 196/981 (19%), Positives = 374/981 (38%), Gaps = 109/981 (11%)

Query: 36  ELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGY 95
           E+  ++++   DK      KK+ V K++    +G D+     + VN + ++    K++ Y
Sbjct: 14  EIFELKAELNSDKK---EKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVY 70

Query: 96  LFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRIL 155
           L++     S  ++  +  N    D    NP    LA+  +  +   ++ E     + + L
Sbjct: 71  LYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCL 130

Query: 156 VAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLC 215
              D    V+++AA+C+ +L+  +  LV    +   +  L++D +  VV  AV+ ++ + 
Sbjct: 131 --KDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIA 188

Query: 216 KKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAA 275
           + +P      + L    +++++    T L + T       W  + +L  L  Y P +D  
Sbjct: 189 ESHPS--SNLLDLNPQSINKLL----TALNECT------EWGQIFILDCLANYMPKDD-- 234

Query: 276 VKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHY--------DSEPNLL 327
                         +AQ   +    + S+A +A++   + +++ +        D    LL
Sbjct: 235 -------------REAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLL 281

Query: 328 VRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQ 387
            +    L   L   E  L+Y+AL ++  +       E +K  +      +K    + V+ 
Sbjct: 282 KKLAPPLVTLLS-AEPELQYVALRNINLIVQKR--PEILKHEMKVFF--VKYNDPIYVKL 336

Query: 388 RAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTIL 447
              D++  +  ++N  Q+++E+  Y    D     + V  +   A K        V T+L
Sbjct: 337 EKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLL 396

Query: 448 NLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGG------ 501
           +LI+   +YV +E       IV  +D  + Y  K  +E++ A  C EN+  +        
Sbjct: 397 DLIQTKVNYVVQEA------IVVIKDIFRKYPNK--YESVIATLC-ENLDSLDEPEARAA 447

Query: 502 --YILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIK-FINLFPETKAT 558
             +I+GE+   I     ++  +  S L   FH  S   +  LL+  +K F+    ET+  
Sbjct: 448 MIWIVGEYAERI----DNADELLESFLEG-FHDESTQVQLQLLTAIVKLFLKKPTETQEL 502

Query: 559 IQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKR 618
           +Q VL   +Q  + + +L+ R   Y  L S         VL E P   E    I   L  
Sbjct: 503 VQQVLSLATQ-DSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLD 561

Query: 619 KKGPGAGSALDDGRRDPSSNDINGG-----MEPTPSTVSTPSPSADLLGLRAAPPPAAPP 673
           +     G+      + PS+  + GG         P T S+ S  +       APP   P 
Sbjct: 562 ELICYIGTLASVYHKPPSA-FVEGGRGVVHKSLPPRTASSESAESPETAPTGAPPGEQPD 620

Query: 674 ASAGAGNLLVDVFD----GPAAQPSLGPTPEEAFLSELEPPAPESPMALLADPAPAADPG 729
                G+LL D+ +     P + P L  +  +    +L     +S +      AP     
Sbjct: 621 VIPAQGDLLGDLLNLDLGPPVSGPPLATSSVQMGAVDLLGGGLDSLIGGTNFVAPPTAAV 680

Query: 730 PEDIGPPIPE-----------ADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLG--RM 776
           P ++G PI                L   +V      L   +   + +   F + +G   M
Sbjct: 681 PANLGAPIGSGLSDLFDLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQVGSISM 740

Query: 777 YLFYGNKT-------SVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIE 829
            L   NK        ++QF   S  +     LQ    +   +        + V  V+ +E
Sbjct: 741 DLQLTNKALQVMTDFAIQFNRNSFGLAPATPLQVHAPLSPNQTVEISLPLSTVGSVMKME 800

Query: 830 CLRDFLTPPLLSVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEA 889
            L +       ++   Y      L +        F +  +M  Q F   WK   +P +  
Sbjct: 801 PLNNLQVAVKNNIDVFYFSTLYPLHI-------LFVEDGKMDRQMFLATWK--DIPNENE 851

Query: 890 QKIFKANHPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEP-N 948
            +    + P++AE   +KL       +   +   ++ +   +  T  + V   LR++P N
Sbjct: 852 AQFQIRDCPLNAEAASSKLQSSNIFTVAKRNVEGQDMLYQSLKLTNGIWVLAELRIQPGN 911

Query: 949 AQAQMYRLTLRTSKEPVSRHL 969
                  L+L+     VS+H+
Sbjct: 912 PSCTDLELSLKCRAPEVSQHV 932


>gi|22027651 adaptor-related protein complex 1 beta 1 subunit
           isoform a [Homo sapiens]
          Length = 949

 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 145/684 (21%), Positives = 275/684 (40%), Gaps = 75/684 (10%)

Query: 36  ELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGY 95
           E+  ++++   DK      KK+ V K++    +G D+     + VN + ++    K++ Y
Sbjct: 14  EIFELKAELNSDKK---EKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVY 70

Query: 96  LFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRIL 155
           L++     S  ++  +  N    D    NP    LA+  +  +   ++ E     + + L
Sbjct: 71  LYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCL 130

Query: 156 VAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLC 215
              D    V+++AA+C+ +L+  +  LV    +   +  L++D +  VV  AV+ ++ + 
Sbjct: 131 --KDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIA 188

Query: 216 KKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAA 275
           + +P      + L    +++++    T L + T       W  + +L  L  Y P +D  
Sbjct: 189 ESHPS--SNLLDLNPQSINKLL----TALNECT------EWGQIFILDCLANYMPKDD-- 234

Query: 276 VKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHY--------DSEPNLL 327
                         +AQ   +    + S+A +A++   + +++ +        D    LL
Sbjct: 235 -------------REAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLL 281

Query: 328 VRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQ 387
            +    L   L   E  L+Y+AL ++  +       E +K  +      +K    + V+ 
Sbjct: 282 KKLAPPLVTLLS-AEPELQYVALRNINLIVQKR--PEILKHEMKVFF--VKYNDPIYVKL 336

Query: 388 RAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTIL 447
              D++  +  ++N  Q+++E+  Y    D     + V  +   A K        V T+L
Sbjct: 337 EKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLL 396

Query: 448 NLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGG------ 501
           +LI+   +YV +E       IV  +D  + Y  K  +E++ A  C EN+  +        
Sbjct: 397 DLIQTKVNYVVQEA------IVVIKDIFRKYPNK--YESVIATLC-ENLDSLDEPEARAA 447

Query: 502 --YILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIK-FINLFPETKAT 558
             +I+GE+   I     ++  +  S L   FH  S   +  LL+  +K F+    ET+  
Sbjct: 448 MIWIVGEYAERI----DNADELLESFLEG-FHDESTQVQLQLLTAIVKLFLKKPTETQEL 502

Query: 559 IQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKR 618
           +Q VL   +Q  + + +L+ R   Y  L S         VL E P   E    I   L  
Sbjct: 503 VQQVLSLATQ-DSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLD 561

Query: 619 KKGPGAGSALDDGRRDPSSNDINGG-----MEPTPSTVSTPSPSADLLGLRAAPPPAAPP 673
           +     G+      + PS+  + GG         P T S+ S  +       APP   P 
Sbjct: 562 ELICYIGTLASVYHKPPSA-FVEGGRGVVHKSLPPRTASSESAESPETAPTGAPPGEQPD 620

Query: 674 ASAGAGNLLVDVFDGPAAQPSLGP 697
                G+LL D+ +     P  GP
Sbjct: 621 VIPAQGDLLGDLLNLDLGPPVSGP 644


>gi|4557469 adaptor-related protein complex 2, beta 1 subunit
           isoform b [Homo sapiens]
          Length = 937

 Score = 90.9 bits (224), Expect = 5e-18
 Identities = 201/1007 (19%), Positives = 387/1007 (38%), Gaps = 145/1007 (14%)

Query: 25  SKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLS 84
           +K+ EI  +  EL N + +           +K+ V K++    +G D+     + VN + 
Sbjct: 10  NKKGEIFELKAELNNEKKE----------KRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQ 59

Query: 85  SNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMG 144
           ++    K++ YL++     S  ++  +  N+   D    NP    LA+  +  +   ++ 
Sbjct: 60  TDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKIT 119

Query: 145 EAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVV 204
           E     + + L   D    V+++AA+C+ +L+  +  +V    +   +  L+ D +  VV
Sbjct: 120 EYLCEPLRKCL--KDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVV 177

Query: 205 TAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRL 264
             AV+ ++ + + +P+     + L    +++++    T L + T       W  + +L  
Sbjct: 178 ANAVAALSEISESHPN--SNLLDLNPQNINKLL----TALNECT------EWGQIFILDC 225

Query: 265 LQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHY---- 320
           L  Y P +D                +AQ   +    + S+A +A++   + +++ +    
Sbjct: 226 LSNYNPKDD---------------REAQSICERVTPRLSHANSAVVLSAVKVLMKFLELL 270

Query: 321 --DSE-PNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINAL 377
             DS+  N+L++        L   E  ++Y+AL ++  +       E +K  I      +
Sbjct: 271 PKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKR--PEILKQEIKVFF--V 326

Query: 378 KTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAV 437
           K    + V+    D++  +  ++N  Q+++E+  Y    D     + V  +   A K   
Sbjct: 327 KYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQ 386

Query: 438 DYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMV 497
                V T+L+LI+   +YV +E       IV  RD  + Y  K  +E++ A  C EN+ 
Sbjct: 387 SAERCVSTLLDLIQTKVNYVVQEA------IVVIRDIFRKYPNK--YESIIATLC-ENLD 437

Query: 498 KVGG--------YILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIK-F 548
            +          +I+GE+   I     ++  +  S L   FH  S   +  LL+  +K F
Sbjct: 438 SLDEPDARAAMIWIVGEYAERI----DNADELLESFLEG-FHDESTQVQLTLLTAIVKLF 492

Query: 549 INLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPER 608
           +    ET+  +Q VL   +Q  + + +L+ R   Y  L S         VL E P   E 
Sbjct: 493 LKKPSETQELVQQVLSLATQ-DSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEE 551

Query: 609 ESSILAKLKRKKGPGAGSALDDGRRDPSS-----------------NDINGGMEPTPSTV 651
              I   L  +     GS      + P++                    + G  P  +T 
Sbjct: 552 TDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTT 611

Query: 652 ST--------PSPS---ADLLGLRAAPPPAAPPASA---GAGNLLVDVFDGPAAQPSLGP 697
           +T        PS      DLL L   PP   P  S+   GA +LL    D    Q  +  
Sbjct: 612 ATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPS 671

Query: 698 TPEEAFLSELEPPAPESPMALLAD------PAPAADPGPEDIGPPIPEAD--ELLNKFVC 749
           +    F     P    S +  L +       AP     P+ +  P  +A   E+   F  
Sbjct: 672 SVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTH 731

Query: 750 KNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFSPTVVHPGDLQTQLAVQT 809
           +   +  E              N     L +    ++QF   S  V+      T LA+ T
Sbjct: 732 RQGHIYME-------------MNFTNKALQHMTDFAIQFNKNSFGVIP----STPLAIHT 774

Query: 810 KRVAAQ-VDGGAQVQ---QVLNIECLRDFLTPPLLSVRFRYGGAPQALTLKLPVTINKFF 865
             +  Q +D    +     V+ +E L +       ++   Y       +  +P+ +  F 
Sbjct: 775 PLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFY------FSCLIPLNV-LFV 827

Query: 866 QPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMDAEVTKAKLLGFGSALLDNVDPNPEN 925
           +  +M  Q F   WK +   + E Q   K  H ++A+   +KL       +   +   ++
Sbjct: 828 EDGKMERQVFLATWKDIP-NENELQFQIKECH-LNADTVSSKLQNNNVYTIAKRNVEGQD 885

Query: 926 FVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCEL 972
            +   +  T  + +   LR++P      Y L+L+     VS+++ ++
Sbjct: 886 MLYQSLKLTNGIWILAELRIQPG--NPNYTLSLKCRAPEVSQYIYQV 930


>gi|71773106 adaptor-related protein complex 2, beta 1 subunit
           isoform a [Homo sapiens]
          Length = 951

 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 206/1020 (20%), Positives = 400/1020 (39%), Gaps = 157/1020 (15%)

Query: 25  SKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLS 84
           +K+ EI  +  EL N + +           +K+ V K++    +G D+     + VN + 
Sbjct: 10  NKKGEIFELKAELNNEKKE----------KRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQ 59

Query: 85  SNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMG 144
           ++    K++ YL++     S  ++  +  N+   D    NP    LA+  +  +   ++ 
Sbjct: 60  TDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKIT 119

Query: 145 EAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVV 204
           E     + + L   D    V+++AA+C+ +L+  +  +V    +   +  L+ D +  VV
Sbjct: 120 EYLCEPLRKCL--KDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVV 177

Query: 205 TAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRL 264
             AV+ ++ + + +P+     + L    +++++    T L + T       W  + +L  
Sbjct: 178 ANAVAALSEISESHPN--SNLLDLNPQNINKLL----TALNECT------EWGQIFILDC 225

Query: 265 LQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHY---- 320
           L  Y P +D                +AQ   +    + S+A +A++   + +++ +    
Sbjct: 226 LSNYNPKDD---------------REAQSICERVTPRLSHANSAVVLSAVKVLMKFLELL 270

Query: 321 --DSE-PNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINAL 377
             DS+  N+L++        L   E  ++Y+AL ++  +       E +K  I      +
Sbjct: 271 PKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKR--PEILKQEIKVFF--V 326

Query: 378 KTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAV 437
           K    + V+    D++  +  ++N  Q+++E+  Y    D     + V  +   A K   
Sbjct: 327 KYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQ 386

Query: 438 DYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMV 497
                V T+L+LI+   +YV +E       IV  RD  + Y  K  +E++ A  C EN+ 
Sbjct: 387 SAERCVSTLLDLIQTKVNYVVQEA------IVVIRDIFRKYPNK--YESIIATLC-ENLD 437

Query: 498 KVGG--------YILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIK-F 548
            +          +I+GE+   I     ++  +  S L   FH  S   +  LL+  +K F
Sbjct: 438 SLDEPDARAAMIWIVGEYAERI----DNADELLESFLEG-FHDESTQVQLTLLTAIVKLF 492

Query: 549 INLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPER 608
           +    ET+  +Q VL   +Q  + + +L+ R   Y  L S         VL E P   E 
Sbjct: 493 LKKPSETQELVQQVLSLATQ-DSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEE 551

Query: 609 ESSILAKLKRKKGPGAGSALDDGRRDPSS-----------------NDINGGMEPTPSTV 651
              I   L  +     GS      + P++                    + G  P  +T 
Sbjct: 552 TDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTT 611

Query: 652 ST--------PSPS---ADLLGLRAAPPPAAPPASA---GAGNLL---VDVFDGPAAQPS 694
           +T        PS      DLL L   PP   P  S+   GA +LL   +D   G      
Sbjct: 612 ATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGG 671

Query: 695 LGPTPE--EAFLSELEPPAPESPMALLADPAPAADPGPEDIGPPIPEADELLNKFVCKNN 752
           +G +P   ++F+          P ++ A  AP+  P P  +   + +  EL         
Sbjct: 672 IGGSPAVGQSFI----------PSSVPATFAPS--PTPAVVSSGLNDLFELSTGIGMAPG 719

Query: 753 GVLFENQLLQIGVKSE-------FRQNLGRMY--LFYGNKT-------SVQFQNFSPTVV 796
           G +    +    VK++       F    G +Y  + + NK        ++QF   S  V+
Sbjct: 720 GYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVI 779

Query: 797 HPGDLQTQLAVQTKRVAAQ-VDGGAQVQ---QVLNIECLRDFLTPPLLSVRFRYGGAPQA 852
                 T LA+ T  +  Q +D    +     V+ +E L +       ++   Y      
Sbjct: 780 P----STPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFY------ 829

Query: 853 LTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMDAEVTKAKLLGFG 912
            +  +P+ +  F +  +M  Q F   WK +   + E Q   K  H ++A+   +KL    
Sbjct: 830 FSCLIPLNV-LFVEDGKMERQVFLATWKDIP-NENELQFQIKECH-LNADTVSSKLQNNN 886

Query: 913 SALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCEL 972
              +   +   ++ +   +  T  + +   LR++P      Y L+L+     VS+++ ++
Sbjct: 887 VYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPG--NPNYTLSLKCRAPEVSQYIYQV 944


>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
           isoform 1 [Homo sapiens]
          Length = 1112

 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 46/201 (22%), Positives = 101/201 (50%), Gaps = 16/201 (7%)

Query: 302 HSNAKNAILFETISLIIHY-----DSEPN--LLVRACNQ-LGQFLQHRETNLRYLALESM 353
           HS +  ++L+E ++ +I          PN    ++ C Q L   ++  + NL+YL L +M
Sbjct: 177 HSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAM 236

Query: 354 CTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYL 413
             +  +    ++V++H D ++  L  ++D S+R RA DLLY M  + N  +IV +++ ++
Sbjct: 237 SKILKTH--PKSVQSHKDLILQCLD-DKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHV 293

Query: 414 ETAD-YAIREEIVLKVAILAE----KYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQI 468
           + A+    R+E++ K+  +      +Y  ++ WY+  ++ L R+ G      +  ++L +
Sbjct: 294 DKAEGTTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRLEGTRHGHLIAAQMLDV 353

Query: 469 VTNRDDVQGYAAKTVFEALQA 489
                 ++ +A   +   L +
Sbjct: 354 AIRVKAIRKFAVSQMSALLDS 374



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 58/242 (23%), Positives = 114/242 (47%), Gaps = 12/242 (4%)

Query: 11  RGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGH 70
           + L   +  IRN   KE E K I++ +  I+ + K D       K   VCKL ++ +LG+
Sbjct: 16  KNLQDLVRGIRN--HKEDEAKYISQCIDEIKQELKQDNIA---VKANAVCKLTYLQMLGY 70

Query: 71  DIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCL 130
           DI +     + ++S++K+T K+IGYL  S   +  +++I L  N I+ DL+S +     +
Sbjct: 71  DISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQYDTGV 130

Query: 131 ALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALC--LLRLYKASPDLVPMGEW 188
           AL  ++   + ++    A DI  ++    +   +++ A L   L  L  ++  +  + E 
Sbjct: 131 ALTGLSCFVTPDLARDLANDIMTLM--SHTKPYIRKKAKLIEPLTNLIHSTSAMSLLYEC 188

Query: 189 TARVVHLLNDQHMGVVTAAVSLITCLCKKN---PDDFKTCVSLAVSRLSRIVSSASTDLQ 245
              V+ +L     G+   + S+  C+ K      D  +    L +  +S+I+ +    +Q
Sbjct: 189 VNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQ 248

Query: 246 DY 247
            +
Sbjct: 249 SH 250


>gi|22547195 sterol regulatory element binding transcription factor
           1 isoform b [Homo sapiens]
          Length = 1147

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 52/169 (30%), Positives = 74/169 (43%), Gaps = 16/169 (9%)

Query: 572 ADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDG 631
           ++  L+Q   E   L +   TD+     E+M      + S    L      G+G+    G
Sbjct: 7   SEAALEQALGEPCDLDAALLTDI-----EDMLQLINNQDSDFPGLFDPPYAGSGA----G 57

Query: 632 RRDPSSNDIN--GGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGP 689
             DP+S D +  G + P P+T+S+ S  A L G +AAP P +PP  A     +      P
Sbjct: 58  GTDPASPDTSSPGSLSPPPATLSS-SLEAFLSGPQAAPSPLSPPQPAPTPLKMYPSM--P 114

Query: 690 AAQPSLGPTPEEAFLSELEPPAPES-PMALLADPAPAADPGPEDIGPPI 737
           A  P  G   E   LS L+ P P+  P ALL    PA  P P+    P+
Sbjct: 115 AFSPGPGIKEESVPLSILQTPTPQPLPGALLPQSFPAPAP-PQFSSTPV 162



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 23/94 (24%), Positives = 39/94 (41%), Gaps = 5/94 (5%)

Query: 643 GMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEA 702
           G +  PS +S P P+   L +  + P  +P       ++ + +   P  QP  G    ++
Sbjct: 89  GPQAAPSPLSPPQPAPTPLKMYPSMPAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQS 148

Query: 703 FLSELEPPAPESPMALLADPAPAADPGPEDIGPP 736
           F +   P    +P  +L  P+P   PG    G P
Sbjct: 149 FPAPAPPQFSSTP--VLGYPSP---PGGFSTGSP 177


>gi|52630419 sterol regulatory element binding transcription factor
           1 isoform a [Homo sapiens]
          Length = 1177

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 44/119 (36%), Positives = 57/119 (47%), Gaps = 9/119 (7%)

Query: 622 PGAGSALDDGRRDPSSNDIN--GGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAG 679
           P AGS    G  DP+S D +  G + P P+T+S+ S  A L G +AAP P +PP  A   
Sbjct: 80  PYAGSGA--GGTDPASPDTSSPGSLSPPPATLSS-SLEAFLSGPQAAPSPLSPPQPAPTP 136

Query: 680 NLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPES-PMALLADPAPAADPGPEDIGPPI 737
             +      PA  P  G   E   LS L+ P P+  P ALL    PA  P P+    P+
Sbjct: 137 LKMYPSM--PAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQSFPAPAP-PQFSSTPV 192



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 23/94 (24%), Positives = 39/94 (41%), Gaps = 5/94 (5%)

Query: 643 GMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEA 702
           G +  PS +S P P+   L +  + P  +P       ++ + +   P  QP  G    ++
Sbjct: 119 GPQAAPSPLSPPQPAPTPLKMYPSMPAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQS 178

Query: 703 FLSELEPPAPESPMALLADPAPAADPGPEDIGPP 736
           F +   P    +P  +L  P+P   PG    G P
Sbjct: 179 FPAPAPPQFSSTP--VLGYPSP---PGGFSTGSP 207


>gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo
           sapiens]
          Length = 594

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 48/136 (35%), Positives = 54/136 (39%), Gaps = 20/136 (14%)

Query: 608 RESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGLRAAP 667
           R  S +    R  GPGAG     GRR   + +  GG        + P PS  LL    A 
Sbjct: 449 RTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGG------EAAAPRPSRVLLPELPAV 502

Query: 668 PPAA-----PPASAGAGNLLVDVFDGPAAQPSL--GPTPEEAFLSELEPPAPESPMALLA 720
            PA      P A+A    L   V  GP A PS   GP P    LS  EPP P +P    A
Sbjct: 503 DPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARA 562

Query: 721 DPAPAA-------DPG 729
            PA  A       DPG
Sbjct: 563 LPAAVASARCSLRDPG 578


>gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo
           sapiens]
          Length = 594

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 48/136 (35%), Positives = 54/136 (39%), Gaps = 20/136 (14%)

Query: 608 RESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGLRAAP 667
           R  S +    R  GPGAG     GRR   + +  GG        + P PS  LL    A 
Sbjct: 449 RTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGG------EAAAPRPSRVLLPELPAV 502

Query: 668 PPAA-----PPASAGAGNLLVDVFDGPAAQPSL--GPTPEEAFLSELEPPAPESPMALLA 720
            PA      P A+A    L   V  GP A PS   GP P    LS  EPP P +P    A
Sbjct: 503 DPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARA 562

Query: 721 DPAPAA-------DPG 729
            PA  A       DPG
Sbjct: 563 LPAAVASARCSLRDPG 578


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 33/118 (27%), Positives = 46/118 (38%), Gaps = 17/118 (14%)

Query: 636 SSNDINGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPA----------------SAGAG 679
           S+ D +    PTP T  TP   + ++    +PPP+ PP+                +  A 
Sbjct: 698 STTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSAS 757

Query: 680 NLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLADPAPAADPG-PEDIGPP 736
               +    P   P   P PEE  LS  + P PE     +A P PA   G PE +  P
Sbjct: 758 ETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSP 815



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 41/180 (22%), Positives = 61/180 (33%), Gaps = 46/180 (25%)

Query: 603 PPFPERESSILAKLKRKKGPGAG-----SALDDGRRDPSSNDINGGM------------- 644
           PP PER +S+       + PGA      ++L     DP+ +D +G               
Sbjct: 610 PPKPERVTSL-------RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPP 662

Query: 645 --------EPTPSTVSTPSPSADLLGLRAAPP------PAAPPASAGAGNLLVDVFDGPA 690
                    P PS   +P+P+A  L   A  P       A+P +       L  + + P 
Sbjct: 663 HPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPV 722

Query: 691 AQPSLGPTPEEAFLSELEPPAPESPMALLADPA-------PAADPGPEDIGPPIPEADEL 743
                 P P         PP  + P  ++  P+       P  DP      PP PE  +L
Sbjct: 723 ISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDL 782



 Score = 33.5 bits (75), Expect = 1.00
 Identities = 30/135 (22%), Positives = 50/135 (37%), Gaps = 7/135 (5%)

Query: 602 MPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLL 661
           +PP PER+           G   G+       +P+++ + G + P  S     SP     
Sbjct: 521 LPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPG-LSPGGSRRPPRSPE---- 575

Query: 662 GLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLAD 721
             R   P +   + +G   L      GP A P     P+   ++ L  P      +L + 
Sbjct: 576 --RTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSL 633

Query: 722 PAPAADPGPEDIGPP 736
            + ++DP P D   P
Sbjct: 634 CSSSSDPAPSDRSGP 648



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 11/107 (10%)

Query: 643 GMEPTPSTVSTPSPSAD-LLGLRAAPP-----PAAPPASAGAGNLLVDVFDGPAAQP--- 693
           G   +P  VS+P+ S+     L+  PP     P APPA A A +    V   P  +P   
Sbjct: 804 GPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGC 863

Query: 694 -SLGPTPEEAFLSELEPPAPESPMALLADPAPAADPGPEDIGPPIPE 739
              G  P E   + L  P+    + L +  AP   P P  +GP  P+
Sbjct: 864 SKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPA-LGPSAPQ 909


>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2852

 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 15/140 (10%)

Query: 594  VLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVST 653
            V  T  E++P  P    S+   L  +KG       + G   P  +  +    P PS    
Sbjct: 1638 VAGTAAEQVPVSPLATRSLEIVLSTEKG-------EAGHSQPMGSPASPQPHPLPSAPPR 1690

Query: 654  PSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQP--SLGPTPEEAFLSELEPPA 711
            P+    +     A PP  P A++     L    DG AA P  SL  T     LS L PP 
Sbjct: 1691 PAQHTTMATRSPALPPETPAAAS-----LSTATDGLAATPFMSLESTRPSQLLSGL-PPD 1744

Query: 712  PESPMALLADPAPAADPGPE 731
               P+A +   AP A PGP+
Sbjct: 1745 TSLPLAKVGTSAPVATPGPK 1764


>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2924

 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 15/140 (10%)

Query: 594  VLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVST 653
            V  T  E++P  P    S+   L  +KG       + G   P  +  +    P PS    
Sbjct: 1710 VAGTAAEQVPVSPLATRSLEIVLSTEKG-------EAGHSQPMGSPASPQPHPLPSAPPR 1762

Query: 654  PSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQP--SLGPTPEEAFLSELEPPA 711
            P+    +     A PP  P A++     L    DG AA P  SL  T     LS L PP 
Sbjct: 1763 PAQHTTMATRSPALPPETPAAAS-----LSTATDGLAATPFMSLESTRPSQLLSGL-PPD 1816

Query: 712  PESPMALLADPAPAADPGPE 731
               P+A +   AP A PGP+
Sbjct: 1817 TSLPLAKVGTSAPVATPGPK 1836


>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 15/140 (10%)

Query: 594  VLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVST 653
            V  T  E++P  P    S+   L  +KG       + G   P  +  +    P PS    
Sbjct: 1638 VAGTAAEQVPVSPLATRSLEIVLSTEKG-------EAGHSQPMGSPASPQPHPLPSAPPR 1690

Query: 654  PSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQP--SLGPTPEEAFLSELEPPA 711
            P+    +     A PP  P A++     L    DG AA P  SL  T     LS L PP 
Sbjct: 1691 PAQHTTMATRSPALPPETPAAAS-----LSTATDGLAATPFMSLESTRPSQLLSGL-PPD 1744

Query: 712  PESPMALLADPAPAADPGPE 731
               P+A +   AP A PGP+
Sbjct: 1745 TSLPLAKVGTSAPVATPGPK 1764


>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 15/140 (10%)

Query: 594  VLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVST 653
            V  T  E++P  P    S+   L  +KG       + G   P  +  +    P PS    
Sbjct: 1710 VAGTAAEQVPVSPLATRSLEIVLSTEKG-------EAGHSQPMGSPASPQPHPLPSAPPR 1762

Query: 654  PSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQP--SLGPTPEEAFLSELEPPA 711
            P+    +     A PP  P A++     L    DG AA P  SL  T     LS L PP 
Sbjct: 1763 PAQHTTMATRSPALPPETPAAAS-----LSTATDGLAATPFMSLESTRPSQLLSGL-PPD 1816

Query: 712  PESPMALLADPAPAADPGPE 731
               P+A +   AP A PGP+
Sbjct: 1817 TSLPLAKVGTSAPVATPGPK 1836


>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 15/140 (10%)

Query: 594  VLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVST 653
            V  T  E++P  P    S+   L  +KG       + G   P  +  +    P PS    
Sbjct: 1638 VAGTAAEQVPVSPLATRSLEIVLSTEKG-------EAGHSQPMGSPASPQPHPLPSAPPR 1690

Query: 654  PSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQP--SLGPTPEEAFLSELEPPA 711
            P+    +     A PP  P A++     L    DG AA P  SL  T     LS L PP 
Sbjct: 1691 PAQHTTMATRSPALPPETPAAAS-----LSTATDGLAATPFMSLESTRPSQLLSGL-PPD 1744

Query: 712  PESPMALLADPAPAADPGPE 731
               P+A +   AP A PGP+
Sbjct: 1745 TSLPLAKVGTSAPVATPGPK 1764


>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 15/140 (10%)

Query: 594  VLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVST 653
            V  T  E++P  P    S+   L  +KG       + G   P  +  +    P PS    
Sbjct: 1710 VAGTAAEQVPVSPLATRSLEIVLSTEKG-------EAGHSQPMGSPASPQPHPLPSAPPR 1762

Query: 654  PSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQP--SLGPTPEEAFLSELEPPA 711
            P+    +     A PP  P A++     L    DG AA P  SL  T     LS L PP 
Sbjct: 1763 PAQHTTMATRSPALPPETPAAAS-----LSTATDGLAATPFMSLESTRPSQLLSGL-PPD 1816

Query: 712  PESPMALLADPAPAADPGPE 731
               P+A +   AP A PGP+
Sbjct: 1817 TSLPLAKVGTSAPVATPGPK 1836


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 36/102 (35%), Positives = 42/102 (41%), Gaps = 8/102 (7%)

Query: 645 EPTPSTVSTPSP-----SADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTP 699
           EP P     P P     SA  L     P PA  PAS  A     +    PA +P+  P P
Sbjct: 56  EPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAP 115

Query: 700 EEAFLSELEPPAPESPMALLADPAPAADP--GPEDIGPPIPE 739
           E A  S  E P PE  +  + +PAP   P   PE    P PE
Sbjct: 116 EPATESAPE-PTPEPALESVPEPAPELTPEVAPELAPEPTPE 156



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 35/120 (29%), Positives = 43/120 (35%), Gaps = 16/120 (13%)

Query: 625 GSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVD 684
           G+A   G   P   +      P P     P P          PPPA PPA         +
Sbjct: 4   GAAAAQGTAPPQDGE-QPAESPEPPPPWPPPP----------PPPAPPPAPPLLSEASPE 52

Query: 685 VFDGPAAQPSLGPTPEEAFLSELE---PPAPESPMALLADPA--PAADPGPEDIGPPIPE 739
               P  + + GP PE    S  E    P PE      ++PA  PA +P PE    P PE
Sbjct: 53  PIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPE 112



 Score = 37.4 bits (85), Expect = 0.069
 Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 17/91 (18%)

Query: 667 PPPAAPPASAGAGNLLVDVFDGPAAQP----SLGPTPEEAFLSELE---PPAPESPMALL 719
           PPP  PPA   A  LL +    P  +P    + GP PE    S  E    P PE      
Sbjct: 31  PPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPA 90

Query: 720 ADPAP----------AADPGPEDIGPPIPEA 740
           ++PAP          A +P PE    P  E+
Sbjct: 91  SEPAPEPATEPAPEPATEPAPEPAPEPATES 121



 Score = 37.0 bits (84), Expect = 0.090
 Identities = 29/100 (29%), Positives = 36/100 (36%), Gaps = 16/100 (16%)

Query: 645 EPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFL 704
           E +P  +  P P         AP P     S  A  L  +    PA +P+  P PE A  
Sbjct: 48  EASPEPIPEPCPEL-------APGPCPEATSESATELYTEPTPEPATEPASEPAPEPA-- 98

Query: 705 SELEPPAPESPMALLADPAPAADPGPEDIGPPIPEADELL 744
                PAPE       +PAP   P P     P P  +  L
Sbjct: 99  ---TEPAPEPA----TEPAPEPAPEPATESAPEPTPEPAL 131



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 20/51 (39%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 692 QPSLGPTPEEAFLSELEPPAPESPMALL--ADPAPAADPGPEDIGPPIPEA 740
           QP+  P P   +     PPAP     LL  A P P  +P PE    P PEA
Sbjct: 19  QPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEA 69


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 42/144 (29%), Positives = 59/144 (40%), Gaps = 14/144 (9%)

Query: 604  PFPERESSILAKLKRKKGPGAGSALDDGRRDPSSND--INGGMEPTPSTVSTPSPSADLL 661
            P PE  +S  A +   + P + +A      +P+S    +    EPT    + P+P     
Sbjct: 1008 PTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067

Query: 662  GLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLAD 721
               A P P  P + A A    V   + P +  +  PTPEE        P PE P    A 
Sbjct: 1068 PAAAVPTPEEPTSPAAA----VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP----AS 1119

Query: 722  PAPAADPGPEDIGPP---IPEADE 742
            PA AA P PE+   P   +P  +E
Sbjct: 1120 PA-AAVPTPEEPASPAAAVPTPEE 1142



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 40/141 (28%), Positives = 55/141 (39%), Gaps = 12/141 (8%)

Query: 604  PFPERESSILAKLKRKKGPGAGSALDDGRRDPSSND--INGGMEPTPSTVSTPSPSADLL 661
            P PE  +S  A +   + P + +A      +P+S    +    EPT    + P+P     
Sbjct: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080

Query: 662  GLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPE---SPMAL 718
               A P P  P + A A    V   + P +  +  PTPEE        P PE   SP A 
Sbjct: 1081 PAAAVPTPEEPTSPAAA----VPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA 1136

Query: 719  LADPAPAADPGPEDIGPPIPE 739
            +  P   A P P     P PE
Sbjct: 1137 VPTPEEPAFPAP---AVPTPE 1154



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 35/136 (25%), Positives = 51/136 (37%), Gaps = 6/136 (4%)

Query: 606  PERESSILAKLKRKKGPGAGSALDDGRRDPSSND--INGGMEPTPSTVSTPSPSADLLGL 663
            PE  +S  A +   + P + +A      +P+S    +    EPT    + P+P       
Sbjct: 997  PEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPA 1056

Query: 664  RAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLADPA 723
             A P P  P + A A    V   + P +  +  PTPEE        P PE P +  A   
Sbjct: 1057 AAVPTPEEPTSPAAA----VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1112

Query: 724  PAADPGPEDIGPPIPE 739
               +P       P PE
Sbjct: 1113 TPEEPASPAAAVPTPE 1128



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 43/155 (27%), Positives = 65/155 (41%), Gaps = 26/155 (16%)

Query: 587  SSVASTDVLATVLEEMP------PFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDI 640
            +SV +   +   LEE        P  E  +S+ A +   + P + +A      +P+S+  
Sbjct: 1200 ASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSS-- 1257

Query: 641  NGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPE 700
                  TP  +S+P+ S         P P  P + A A    V   + PA+  +  PTPE
Sbjct: 1258 -AAAVLTPEELSSPAASV--------PTPEEPASPAAA----VSNLEEPASPAAAVPTPE 1304

Query: 701  EAFLSELEPPAPESPMALLADPAPAADPGPEDIGP 735
             A +     P PE P    A PA AA P  E++ P
Sbjct: 1305 VAAIPAASVPTPEVP----AIPA-AAVPPMEEVSP 1334



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 30/79 (37%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 665  AAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEE-----AFLSELEPPAPESPMALL 719
            AA P    P S+ A  L  +    PAA     PTPEE     A +S LE PA  SP A +
Sbjct: 1246 AAVPTLEEPTSSAAAVLTPEELSSPAASV---PTPEEPASPAAAVSNLEEPA--SPAAAV 1300

Query: 720  ADPAPAADPGPEDIGPPIP 738
              P  AA P      P +P
Sbjct: 1301 PTPEVAAIPAASVPTPEVP 1319



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 30/111 (27%), Positives = 39/111 (35%), Gaps = 16/111 (14%)

Query: 645  EPTPSTVSTPSPSADLLGLRAAPPPAAP------PASAGAG----------NLLVDVFDG 688
            EPT    S P+P+A +  L     PAA       PAS  A              V   + 
Sbjct: 1194 EPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEE 1253

Query: 689  PAAQPSLGPTPEEAFLSELEPPAPESPMALLADPAPAADPGPEDIGPPIPE 739
            P +  +   TPEE        P PE P +  A  +   +P       P PE
Sbjct: 1254 PTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE 1304



 Score = 34.3 bits (77), Expect = 0.59
 Identities = 34/139 (24%), Positives = 49/139 (35%), Gaps = 6/139 (4%)

Query: 604  PFPERESSILAKLKRKKGPGAGSALDDGRRDPSSND--INGGMEPTPSTVSTPSPSADLL 661
            P PE  +S  A +   + P + +A      +P+S    +    EP     + P+P     
Sbjct: 1073 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPAS 1132

Query: 662  GLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLAD 721
               A P P  P   A A    V   +  A+     PTPEE+       P P    +  A 
Sbjct: 1133 PAAAVPTPEEPAFPAPA----VPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAV 1188

Query: 722  PAPAADPGPEDIGPPIPEA 740
             A   +P       P P A
Sbjct: 1189 VATLEEPTSPAASVPTPAA 1207



 Score = 33.9 bits (76), Expect = 0.76
 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 4/95 (4%)

Query: 645  EPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFL 704
            EP  + V   +P        A P P  P + A A    V   + P +  +  P PEE   
Sbjct: 986  EPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAA----VPTPEEPTSPAAAVPPPEEPTS 1041

Query: 705  SELEPPAPESPMALLADPAPAADPGPEDIGPPIPE 739
                 P PE P +  A      +P       P PE
Sbjct: 1042 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1076



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 24/92 (26%), Positives = 33/92 (35%), Gaps = 4/92 (4%)

Query: 648  PSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSEL 707
            P T    +P   +        P  P  +A    + V   + PA+  +  PTPEE      
Sbjct: 963  PITEEDGTPEGPVTPATTVHAPEEPDTAA----VRVSTPEEPASPAAAVPTPEEPTSPAA 1018

Query: 708  EPPAPESPMALLADPAPAADPGPEDIGPPIPE 739
              P PE P +  A   P  +P       P PE
Sbjct: 1019 AVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPE 1050


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 51/152 (33%), Positives = 60/152 (39%), Gaps = 19/152 (12%)

Query: 600 EEMPPF-PERESSILAKLKRKKGPGAGSALDDGRRDPSSNDI--------NGGMEPTPST 650
           E+ PP  P R S++  K++  +  G    L  G  D  S +I        +GG  PTP  
Sbjct: 463 EKAPPAAPTRPSALELKVEELEEKGLIRILR-GPGDAVSIEILPVAVATPSGGDAPTPG- 520

Query: 651 VSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPP 710
           V T SPS DL       P AAPP       L       P+A P   P P     S   PP
Sbjct: 521 VPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPG----SPEPPP 576

Query: 711 APESPMALLADPAPAADP----GPEDIGPPIP 738
           AP  P  L   P P   P    GP    PP P
Sbjct: 577 APPLPGDLPPPPPPPPPPPGTDGPVPPPPPPP 608



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 45/215 (20%), Positives = 81/215 (37%), Gaps = 27/215 (12%)

Query: 542 LSTYIKFINLFPETKATIQ-----------GVLRAGSQLRNADVELQQRAVEYLTLSSVA 590
           L  Y++ + L    K  +Q           G L   ++ +NA +E  +   E + L +  
Sbjct: 355 LDLYLERLRLTESDKLQVQIQAYLDNIFDVGALLEDTETKNAVLEHMEELQEQVALLTER 414

Query: 591 STDVLATVLEEMPPFPERESSILAKLKR-KKGPGAGSALDDGRRDPSSNDINGGMEPTPS 649
             D     + ++    ++ S    +L+  ++     +A+   RR P         EP  +
Sbjct: 415 LRDAENESMAKIAELEKQLSQARKELETLRERFSESTAMGASRRPP---------EPEKA 465

Query: 650 TVSTPS-PSADLLGLRAAPPPAAPPASAGAGNLL-VDVFDGPAAQPSLGPTPEEAFLSEL 707
             + P+ PSA  L +             G G+ + +++     A PS G  P       +
Sbjct: 466 PPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPG----V 521

Query: 708 EPPAPESPMALLADPAPAADPGPEDIGPPIPEADE 742
              +P   +A  A+PAP A P P    P +P   E
Sbjct: 522 PTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQE 556


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 39/125 (31%), Positives = 47/125 (37%), Gaps = 24/125 (19%)

Query: 622  PGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNL 681
            PG  SA  +G  +P    +     PTP    TP P          PPP  PP  A     
Sbjct: 1437 PGLPSANSNGTPEPPL--LEEKPPPTPPPAPTPQPQP--------PPPPPPPQPAL---- 1482

Query: 682  LVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLADPAPAADP---GPEDIGPPIP 738
                   P+  P + PTP       L PP P +  +    P PAA P    PE+   P P
Sbjct: 1483 -------PSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535

Query: 739  EADEL 743
            E  EL
Sbjct: 1536 EDPEL 1540



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 42/162 (25%), Positives = 56/162 (34%), Gaps = 43/162 (26%)

Query: 579  RAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSN 638
            +A  ++ L+S+   D L    EE   FP  E             G G+A D G+  P  +
Sbjct: 922  KAPRFVPLTSICFPDSLLQD-EERSFFPTMEEMF----------GGGAADDYGKAGPPED 970

Query: 639  --DINGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLG 696
              D   G  P P       P+ D  G      P  P  ++GAG             P LG
Sbjct: 971  EGDPKAGAGPPPGP-----PAYDPYG------PYCPGRASGAG----------PETPGLG 1009

Query: 697  PTPEEAFLSELEPPAPESPMALLADPAPAADPGPEDIGPPIP 738
              P +          PE P  + A+P      GP    PP P
Sbjct: 1010 LDPNKP---------PELPSTVNAEPLGLIQSGPHQAAPPPP 1042



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 23/75 (30%), Positives = 27/75 (36%), Gaps = 19/75 (25%)

Query: 670  AAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLADPAPAADPG 729
            A  P SAG          G +A P   P P         PP PE+P    ++  P   P 
Sbjct: 1680 AKNPVSAG----------GSSAPPPKAPAP---------PPKPETPEKTTSEKPPEQTPE 1720

Query: 730  PEDIGPPIPEADELL 744
                 PP PE   LL
Sbjct: 1721 TAMPEPPAPEKPSLL 1735


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 40/153 (26%), Positives = 57/153 (37%), Gaps = 9/153 (5%)

Query: 597 TVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSS-NDINGGMEPTPSTVSTPS 655
           T L ++    +R +  +   K     G GSA   G   P +  D+  G  P    V  P+
Sbjct: 57  TRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFP----VLRPA 112

Query: 656 PSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESP 715
              D+ G +    P +   S    N  +     P A P LG T E    +   PP P  P
Sbjct: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVP 172

Query: 716 MALLADPAPAADPGPEDIGPPIPEADELLNKFV 748
               A P P   P P  + PP+P +  +    V
Sbjct: 173 ----APPPPTPPPPPPPLPPPLPSSSPIKTPLV 201



 Score = 33.9 bits (76), Expect = 0.76
 Identities = 31/105 (29%), Positives = 37/105 (35%), Gaps = 17/105 (16%)

Query: 646 PTPSTVSTPSPSADLLGLRAAPPPAAP---PASAGAGNLLVDVFDGPAAQPSLGPTPEEA 702
           P P     P P A +L  +A  P  AP   P       LL      P   P L   P   
Sbjct: 228 PPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLP-----PCGYPGLKAEPASP 282

Query: 703 FLSELEPPAPESPMALLADPAPAAD-PGP--------EDIGPPIP 738
                EPPAP  P+   A  +P A  P P         +  PP+P
Sbjct: 283 AQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLP 327



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 39/142 (27%), Positives = 55/142 (38%), Gaps = 26/142 (18%)

Query: 619 KKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGLRAAPP----PAAPPA 674
           K G G GS     R    +  I+G + P P++    + S      R APP    PA PP 
Sbjct: 121 KTGQGPGSRAPSPRLP--NKTISGPLIP-PASPRLGNTSEAHGAARTAPPRPNVPAPPPP 177

Query: 675 SAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSE--LEPPAP--ESPMALLADPAPAA---- 726
           +             P   P   P P  + +    + PP P  +  + ++A P P A    
Sbjct: 178 TPP-----------PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPP 226

Query: 727 DPGPEDIGPPIPEADELLNKFV 748
            P P    PP+P A  L +K V
Sbjct: 227 PPPPPPTPPPLPPASVLSDKAV 248


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 37/117 (31%), Positives = 48/117 (41%), Gaps = 16/117 (13%)

Query: 635 PSSNDINGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQP- 693
           P+   ++     TPS  + PSPSA         PPA PP+ A            P  Q  
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS------LGSPTLQAT 338

Query: 694 -SLGPTPEEAFLSELEPPAPESPMALL-----ADPAPAADPGPEDIGPPIPEADELL 744
            S  P+P    LS L  P P++P AL      A P+P A P    +  P P+A   L
Sbjct: 339 HSFLPSPP---LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 45/172 (26%), Positives = 61/172 (35%), Gaps = 19/172 (11%)

Query: 584 LTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGG 643
           L   S  + + LA  L + P  P     + A       P    +     + P S      
Sbjct: 381 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS------ 434

Query: 644 MEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLG------- 696
           +   P  V    P++  +   A PPP APP  A     L      P A P+L        
Sbjct: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK--PPPQAPPALATPPLQAL 492

Query: 697 PTPEEAFLSELE-PPAPESPMALLADPAPAADP---GPEDIGPPIPEADELL 744
           P+P  +F  +    P+   PM+ LA P P A P    P    PP P A   L
Sbjct: 493 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 544



 Score = 37.0 bits (84), Expect = 0.090
 Identities = 41/156 (26%), Positives = 55/156 (35%), Gaps = 20/156 (12%)

Query: 588 SVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPT 647
           SV+S    +T   E  P   R  S    L+R       S+         S     G    
Sbjct: 199 SVSSASEHSTT--EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256

Query: 648 PSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSEL 707
           P+  S P P     GL+A  PP   P    A   L  +   P A P           S  
Sbjct: 257 PAHPSQPKPK----GLQALRPPQVTPPRKDAAPALGPLSSSPLATP-----------SPS 301

Query: 708 EPPAPESPMALLADPAPAADPGPE---DIGPPIPEA 740
            PP+P +P +L   P+P A P  +    +G P  +A
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 43/162 (26%), Positives = 56/162 (34%), Gaps = 16/162 (9%)

Query: 591 STDVLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTP-S 649
           S+  LAT     PP P    S+         P + +    G   P+    +  +   P S
Sbjct: 291 SSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG--SPTLQATHSFLPSPPLS 348

Query: 650 TVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAA---------QPSLGPTPE 700
            ++TP P A      A PP  APP+   +  L       P A         Q    P P 
Sbjct: 349 PLATPPPQAP--PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 406

Query: 701 EAFLSELEPPA--PESPMALLADPAPAADPGPEDIGPPIPEA 740
               +   PPA  P SP A     AP +   P    PP P A
Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 448



 Score = 33.9 bits (76), Expect = 0.76
 Identities = 30/100 (30%), Positives = 40/100 (40%), Gaps = 18/100 (18%)

Query: 646 PTPSTVSTPSPSAD---LLGLRAAP--PPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPE 700
           P  S ++TPSP A     + L  AP  PP +PP  A            P + P+  P   
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA------------PFSPPASPPVSP 423

Query: 701 EAFLSELEPPAPESPMALLADPAPAADPGPEDIGPPIPEA 740
            A      PP+  +P  L   P+P A P       P P+A
Sbjct: 424 SATPPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQA 462


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,623,196
Number of Sequences: 37866
Number of extensions: 1882228
Number of successful extensions: 11621
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 601
Number of HSP's that attempted gapping in prelim test: 9149
Number of HSP's gapped (non-prelim): 2408
length of query: 977
length of database: 18,247,518
effective HSP length: 112
effective length of query: 865
effective length of database: 14,006,526
effective search space: 12115644990
effective search space used: 12115644990
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.