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Search of human proteins with 19743907
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19743907 RAR-related orphan receptor B [Homo sapiens]
(459 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19743907 RAR-related orphan receptor B [Homo sapiens] 934 0.0
gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens] 585 e-167
gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens] 584 e-167
gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens] 583 e-166
gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens] 581 e-166
gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens] 437 e-122
gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens] 434 e-121
gi|224177493 nuclear receptor subfamily 1, group D, member 2 iso... 138 9e-33
gi|224177491 nuclear receptor subfamily 1, group D, member 2 iso... 138 9e-33
gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Hom... 133 4e-31
gi|45545405 nuclear receptor subfamily 5, group A, member 2 isof... 127 2e-29
gi|4504343 nuclear receptor subfamily 5, group A, member 2 isofo... 127 2e-29
gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Hom... 125 8e-29
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 119 6e-27
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 119 6e-27
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 117 2e-26
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 117 3e-26
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 117 3e-26
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 117 3e-26
gi|53729327 nuclear receptor subfamily 6, group A, member 1 isof... 115 8e-26
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 115 1e-25
gi|53729325 nuclear receptor subfamily 6, group A, member 1 isof... 115 1e-25
gi|50348666 peroxisome proliferative activated receptor, alpha [... 114 2e-25
gi|7549811 peroxisome proliferative activated receptor, alpha [H... 114 2e-25
gi|116284373 peroxisome proliferative activated receptor gamma i... 114 2e-25
gi|20336229 peroxisome proliferative activated receptor gamma is... 114 2e-25
gi|116284368 peroxisome proliferative activated receptor gamma i... 114 2e-25
gi|116284370 peroxisome proliferative activated receptor gamma i... 114 2e-25
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 113 3e-25
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 112 5e-25
>gi|19743907 RAR-related orphan receptor B [Homo sapiens]
Length = 459
Score = 934 bits (2413), Expect = 0.0
Identities = 459/459 (100%), Positives = 459/459 (100%)
Query: 1 MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRN 60
MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRN
Sbjct: 1 MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRN 60
Query: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALAR 120
RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALAR
Sbjct: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALAR 120
Query: 121 VYSSSISNGLSNLNNETSGTYANGHVIDLPKSEGYYNVDSGQPSPDQSGLDMTGIKQIKQ 180
VYSSSISNGLSNLNNETSGTYANGHVIDLPKSEGYYNVDSGQPSPDQSGLDMTGIKQIKQ
Sbjct: 121 VYSSSISNGLSNLNNETSGTYANGHVIDLPKSEGYYNVDSGQPSPDQSGLDMTGIKQIKQ 180
Query: 181 EPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQLAWQ 240
EPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQLAWQ
Sbjct: 181 EPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQLAWQ 240
Query: 241 THTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCL 300
THTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCL
Sbjct: 241 THTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCL 300
Query: 301 EVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIA 360
EVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIA
Sbjct: 301 EVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIA 360
Query: 361 LFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPTITAVC 420
LFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPTITAVC
Sbjct: 361 LFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPTITAVC 420
Query: 421 NLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPDCATGCK 459
NLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPDCATGCK
Sbjct: 421 NLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPDCATGCK 459
>gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]
Length = 468
Score = 585 bits (1508), Expect = e-167
Identities = 292/459 (63%), Positives = 354/459 (77%), Gaps = 14/459 (3%)
Query: 1 MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRN 60
M+AQIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQ+NA+YSCPRQ+NCLIDRT+RN
Sbjct: 9 MKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRN 68
Query: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQ-QRLQEQRQQQSGEAEALA 119
RCQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSLYAEVQKH+ Q+ Q QQQ GEAE L
Sbjct: 69 RCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLT 128
Query: 120 RVYSSSISNGLSNLNNETSGTYANGHVIDLPKSEG-----YYNVDSGQPSPDQSGLDMTG 174
Y+ S +NGL+ L+++ S Y +GH + K++ Y ++ QPSPDQSGLD+ G
Sbjct: 129 PTYNIS-ANGLTELHDDLSN-YIDGHTPEGSKADSAVSSFYLDI---QPSPDQSGLDING 183
Query: 175 IKQIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEEL 234
IK EPI D T F Y SF NG+ +P ++M E++ +AQNI KSHLETCQY EEL
Sbjct: 184 IKP---EPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL 240
Query: 235 HQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILL 294
Q+ WQT EEI+ YQ+K RE +WQ CAI+IT AIQYVVEFAKRI GFMELCQNDQI+L
Sbjct: 241 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 300
Query: 295 LKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQL 354
LK+G LEVV +RMCRAF+ NNTV F+GKY +FK+LG +D ++ F+F K+LCS+ L
Sbjct: 301 LKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHL 360
Query: 355 TEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIP 414
TE+EIALFS+ VL+S DR+WL E K++KLQ+KI ALQHV+QKNH +D L KLI K+
Sbjct: 361 TEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVS 420
Query: 415 TITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPD 453
T+ A+C H EKL FK +P+IV FPPLYKELF +
Sbjct: 421 TLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSE 459
>gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]
Length = 556
Score = 584 bits (1506), Expect = e-167
Identities = 292/459 (63%), Positives = 353/459 (76%), Gaps = 14/459 (3%)
Query: 1 MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRN 60
M AQIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQ+NA+YSCPRQ+NCLIDRT+RN
Sbjct: 97 MNAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRN 156
Query: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQ-QRLQEQRQQQSGEAEALA 119
RCQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSLYAEVQKH+ Q+ Q QQQ GEAE L
Sbjct: 157 RCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLT 216
Query: 120 RVYSSSISNGLSNLNNETSGTYANGHVIDLPKSEG-----YYNVDSGQPSPDQSGLDMTG 174
Y+ S +NGL+ L+++ S Y +GH + K++ Y ++ QPSPDQSGLD+ G
Sbjct: 217 PTYNIS-ANGLTELHDDLSN-YIDGHTPEGSKADSAVSSFYLDI---QPSPDQSGLDING 271
Query: 175 IKQIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEEL 234
IK EPI D T F Y SF NG+ +P ++M E++ +AQNI KSHLETCQY EEL
Sbjct: 272 IKP---EPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL 328
Query: 235 HQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILL 294
Q+ WQT EEI+ YQ+K RE +WQ CAI+IT AIQYVVEFAKRI GFMELCQNDQI+L
Sbjct: 329 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 388
Query: 295 LKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQL 354
LK+G LEVV +RMCRAF+ NNTV F+GKY +FK+LG +D ++ F+F K+LCS+ L
Sbjct: 389 LKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHL 448
Query: 355 TEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIP 414
TE+EIALFS+ VL+S DR+WL E K++KLQ+KI ALQHV+QKNH +D L KLI K+
Sbjct: 449 TEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVS 508
Query: 415 TITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPD 453
T+ A+C H EKL FK +P+IV FPPLYKELF +
Sbjct: 509 TLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSE 547
>gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]
Length = 548
Score = 583 bits (1503), Expect = e-166
Identities = 291/458 (63%), Positives = 353/458 (77%), Gaps = 14/458 (3%)
Query: 2 RAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNR 61
+AQIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQ+NA+YSCPRQ+NCLIDRT+RNR
Sbjct: 90 KAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNR 149
Query: 62 CQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQ-QRLQEQRQQQSGEAEALAR 120
CQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSLYAEVQKH+ Q+ Q QQQ GEAE L
Sbjct: 150 CQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTP 209
Query: 121 VYSSSISNGLSNLNNETSGTYANGHVIDLPKSEG-----YYNVDSGQPSPDQSGLDMTGI 175
Y+ S +NGL+ L+++ S Y +GH + K++ Y ++ QPSPDQSGLD+ GI
Sbjct: 210 TYNIS-ANGLTELHDDLSN-YIDGHTPEGSKADSAVSSFYLDI---QPSPDQSGLDINGI 264
Query: 176 KQIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELH 235
K EPI D T F Y SF NG+ +P ++M E++ +AQNI KSHLETCQY EEL
Sbjct: 265 KP---EPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQ 321
Query: 236 QLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLL 295
Q+ WQT EEI+ YQ+K RE +WQ CAI+IT AIQYVVEFAKRI GFMELCQNDQI+LL
Sbjct: 322 QITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLL 381
Query: 296 KSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLT 355
K+G LEVV +RMCRAF+ NNTV F+GKY +FK+LG +D ++ F+F K+LCS+ LT
Sbjct: 382 KAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLT 441
Query: 356 EEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPT 415
E+EIALFS+ VL+S DR+WL E K++KLQ+KI ALQHV+QKNH +D L KLI K+ T
Sbjct: 442 EDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVST 501
Query: 416 ITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPD 453
+ A+C H EKL FK +P+IV FPPLYKELF +
Sbjct: 502 LRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSE 539
>gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]
Length = 523
Score = 581 bits (1498), Expect = e-166
Identities = 290/457 (63%), Positives = 352/457 (77%), Gaps = 14/457 (3%)
Query: 3 AQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRC 62
+QIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQ+NA+YSCPRQ+NCLIDRT+RNRC
Sbjct: 66 SQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 125
Query: 63 QHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQ-QRLQEQRQQQSGEAEALARV 121
QHCRLQKCLA+GMSRDAVKFGRMSKKQRDSLYAEVQKH+ Q+ Q QQQ GEAE L
Sbjct: 126 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 185
Query: 122 YSSSISNGLSNLNNETSGTYANGHVIDLPKSEG-----YYNVDSGQPSPDQSGLDMTGIK 176
Y+ S +NGL+ L+++ S Y +GH + K++ Y ++ QPSPDQSGLD+ GIK
Sbjct: 186 YNIS-ANGLTELHDDLSN-YIDGHTPEGSKADSAVSSFYLDI---QPSPDQSGLDINGIK 240
Query: 177 QIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQ 236
EPI D T F Y SF NG+ +P ++M E++ +AQNI KSHLETCQY EEL Q
Sbjct: 241 P---EPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQ 297
Query: 237 LAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLK 296
+ WQT EEI+ YQ+K RE +WQ CAI+IT AIQYVVEFAKRI GFMELCQNDQI+LLK
Sbjct: 298 ITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLK 357
Query: 297 SGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTE 356
+G LEVV +RMCRAF+ NNTV F+GKY +FK+LG +D ++ F+F K+LCS+ LTE
Sbjct: 358 AGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTE 417
Query: 357 EEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPTI 416
+EIALFS+ VL+S DR+WL E K++KLQ+KI ALQHV+QKNH +D L KLI K+ T+
Sbjct: 418 DEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTL 477
Query: 417 TAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPD 453
A+C H EKL FK +P+IV FPPLYKELF +
Sbjct: 478 RALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSE 514
>gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens]
Length = 497
Score = 437 bits (1124), Expect = e-122
Identities = 242/497 (48%), Positives = 327/497 (65%), Gaps = 53/497 (10%)
Query: 1 MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRN 60
MR QIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA+YSC RQ+NC IDRT+RN
Sbjct: 1 MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRN 60
Query: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQ------SGE 114
RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSL+AEVQK Q+ Q+Q+Q+ +G
Sbjct: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGA 120
Query: 115 AEALARVYSSSISNGLSNLNN---------------ETSGT---YANG-----------H 145
A Y+ + +G L + + SG+ Y+N H
Sbjct: 121 QGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCH 180
Query: 146 VIDLP---KSEG---YYNVDSGQPSPDQSGLDMTGIKQIKQEPIYDLTSVPNLFTYSSFN 199
+ P K+EG +Y+ S Q +PD+ GL ++ + + +L P+ + SF
Sbjct: 181 LEYSPERGKAEGRESFYSTGS-QLTPDRCGLRF---EEHRHPGLGELGQGPDSYGSPSFR 236
Query: 200 NGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALW 259
+ AP ++TEI+ + Q++ KS+ ETCQ +E+L + + EE+ YQ KS +W
Sbjct: 237 STPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMW 296
Query: 260 QQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVL 319
++CA +T AIQYVVEFAKR++GFMELCQNDQI+LLK+G +EVVLVRMCRA+N N TV
Sbjct: 297 ERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVF 356
Query: 320 FEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPR 379
FEGKYGGM++F+ALG +L++ FDF+ +L +L +E+EIAL+++ VLI+ R L E R
Sbjct: 357 FEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKR 416
Query: 380 KVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIP---TITAVCNLHGEKLQVFKQSHPE 436
KV++LQ + A H + K H ++AK+P + ++C+ H E+LQ+F+ HP
Sbjct: 417 KVEQLQYNLELAFHHHLCKTHRQ-----SILAKLPPKGKLRSLCSQHVERLQIFQHLHPI 471
Query: 437 IVNTLFPPLYKELFNPD 453
+V FPPLYKELF+ +
Sbjct: 472 VVQAAFPPLYKELFSTE 488
>gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens]
Length = 518
Score = 434 bits (1115), Expect = e-121
Identities = 240/495 (48%), Positives = 326/495 (65%), Gaps = 53/495 (10%)
Query: 3 AQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRC 62
+QIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA+YSC RQ+NC IDRT+RNRC
Sbjct: 24 SQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRC 83
Query: 63 QHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQ------SGEAE 116
QHCRLQKCLALGMSRDAVKFGRMSKKQRDSL+AEVQK Q+ Q+Q+Q+ +G
Sbjct: 84 QHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQG 143
Query: 117 ALARVYSSSISNGLSNLNN---------------ETSGT---YANG-----------HVI 147
A Y+ + +G L + + SG+ Y+N H+
Sbjct: 144 ADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCHLE 203
Query: 148 DLP---KSEG---YYNVDSGQPSPDQSGLDMTGIKQIKQEPIYDLTSVPNLFTYSSFNNG 201
P K+EG +Y+ S Q +PD+ GL ++ + + +L P+ + SF +
Sbjct: 204 YSPERGKAEGRESFYSTGS-QLTPDRCGLRF---EEHRHPGLGELGQGPDSYGSPSFRST 259
Query: 202 QLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQ 261
AP ++TEI+ + Q++ KS+ ETCQ +E+L + + EE+ YQ KS +W++
Sbjct: 260 PEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWER 319
Query: 262 CAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFE 321
CA +T AIQYVVEFAKR++GFMELCQNDQI+LLK+G +EVVLVRMCRA+N N TV FE
Sbjct: 320 CAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFE 379
Query: 322 GKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKV 381
GKYGGM++F+ALG +L++ FDF+ +L +L +E+EIAL+++ VLI+ R L E RKV
Sbjct: 380 GKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKV 439
Query: 382 QKLQEKIYFALQHVIQKNHLDDETLAKLIAKIP---TITAVCNLHGEKLQVFKQSHPEIV 438
++LQ + A H + K H ++AK+P + ++C+ H E+LQ+F+ HP +V
Sbjct: 440 EQLQYNLELAFHHHLCKTHRQ-----SILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVV 494
Query: 439 NTLFPPLYKELFNPD 453
FPPLYKELF+ +
Sbjct: 495 QAAFPPLYKELFSTE 509
>gi|224177493 nuclear receptor subfamily 1, group D, member 2
isoform 2 [Homo sapiens]
Length = 504
Score = 138 bits (348), Expect = 9e-33
Identities = 74/185 (40%), Positives = 121/185 (65%), Gaps = 3/185 (1%)
Query: 253 KSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFN 312
KS +W++ ++ T A++ VVEFAKRI GF +L Q+DQ+ LLK+G EV++VR F+
Sbjct: 321 KSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFD 380
Query: 313 PLNNTVLF-EGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPD 371
TV F GK + ++G+ DL+N F+F++ L +LQL++EE++LF++ VL+S D
Sbjct: 381 AKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSAD 440
Query: 372 RAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETL-AKLIAKIPTITAVCNLHGEKLQVF 430
R+ + V+ LQE + AL+ +I KNH ++ ++ KL+ K+P + ++ N+H E+L F
Sbjct: 441 RSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAF 500
Query: 431 KQSHP 435
K HP
Sbjct: 501 K-VHP 504
Score = 125 bits (313), Expect = 1e-28
Identities = 66/170 (38%), Positives = 94/170 (55%), Gaps = 14/170 (8%)
Query: 7 VIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYS-CPRQRNCLIDRTNRNRCQHC 65
V+ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + NC I R NRNRCQ C
Sbjct: 25 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQC 84
Query: 66 RLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALARVYSSS 125
R +KCL++GMSRDAV+FGR+ K+++ + E+Q + + + +S
Sbjct: 85 RFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQ-------------FSGH 131
Query: 126 ISNGLSNLNNETSGTYANGHVIDLPKSEGYYNVDSGQPSPDQSGLDMTGI 175
+ N ++E + A + P+ E S PS D + ++ G+
Sbjct: 132 LQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKSSSPPSSDFAKEEVIGM 181
>gi|224177491 nuclear receptor subfamily 1, group D, member 2
isoform 1 [Homo sapiens]
Length = 579
Score = 138 bits (348), Expect = 9e-33
Identities = 74/185 (40%), Positives = 121/185 (65%), Gaps = 3/185 (1%)
Query: 253 KSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFN 312
KS +W++ ++ T A++ VVEFAKRI GF +L Q+DQ+ LLK+G EV++VR F+
Sbjct: 396 KSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFD 455
Query: 313 PLNNTVLF-EGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPD 371
TV F GK + ++G+ DL+N F+F++ L +LQL++EE++LF++ VL+S D
Sbjct: 456 AKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSAD 515
Query: 372 RAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETL-AKLIAKIPTITAVCNLHGEKLQVF 430
R+ + V+ LQE + AL+ +I KNH ++ ++ KL+ K+P + ++ N+H E+L F
Sbjct: 516 RSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAF 575
Query: 431 KQSHP 435
K HP
Sbjct: 576 K-VHP 579
Score = 125 bits (313), Expect = 1e-28
Identities = 66/170 (38%), Positives = 94/170 (55%), Gaps = 14/170 (8%)
Query: 7 VIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYS-CPRQRNCLIDRTNRNRCQHC 65
V+ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + NC I R NRNRCQ C
Sbjct: 100 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQC 159
Query: 66 RLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALARVYSSS 125
R +KCL++GMSRDAV+FGR+ K+++ + E+Q + + + +S
Sbjct: 160 RFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQ-------------FSGH 206
Query: 126 ISNGLSNLNNETSGTYANGHVIDLPKSEGYYNVDSGQPSPDQSGLDMTGI 175
+ N ++E + A + P+ E S PS D + ++ G+
Sbjct: 207 LQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKSSSPPSSDFAKEEVIGM 256
>gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Homo
sapiens]
Length = 614
Score = 133 bits (334), Expect = 4e-31
Identities = 71/178 (39%), Positives = 112/178 (62%), Gaps = 2/178 (1%)
Query: 256 EALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLN 315
+ +W+ ++ T A++ VVEFAK I GF +L Q+DQ+ LLK+G EV++VR FN +
Sbjct: 433 QEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKD 492
Query: 316 NTVLFEGKYG-GMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAW 374
TV+F + +Q A+G DL++ FDF++ L SL LTEEE+ LF++ VL+S DR+
Sbjct: 493 QTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSG 552
Query: 375 LIEPRKVQKLQEKIYFALQHVIQKNH-LDDETLAKLIAKIPTITAVCNLHGEKLQVFK 431
+ V++LQE + AL+ ++ KN L+ KL+ K+P + + N+H EKL F+
Sbjct: 553 MENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFR 610
Score = 127 bits (319), Expect = 2e-29
Identities = 58/106 (54%), Positives = 72/106 (67%), Gaps = 1/106 (0%)
Query: 7 VIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYS-CPRQRNCLIDRTNRNRCQHC 65
V+ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + NC I R NRNRCQ C
Sbjct: 129 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQC 188
Query: 66 RLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQ 111
R +KCL++GMSRDAV+FGR+ K+++ + AE+Q Q Q
Sbjct: 189 RFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQ 234
>gi|45545405 nuclear receptor subfamily 5, group A, member 2 isoform
1 [Homo sapiens]
Length = 541
Score = 127 bits (320), Expect = 2e-29
Identities = 124/460 (26%), Positives = 221/460 (48%), Gaps = 51/460 (11%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQK 69
C +CGDK SG HYG++TCE CKGFF+R+ QNN Y+C +NC ID+T R RC +CR QK
Sbjct: 86 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQK 145
Query: 70 CLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQ---QQSG-EAEALARVYSS- 124
CL++GM +AV+ RM + + + + K + L++Q++ + +G + EA+++V +
Sbjct: 146 CLSVGMKLEAVRADRM--RGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAM 203
Query: 125 ----SISNGLSNLNNETSGTYANGHVI---DLPKSEGYYNVDSGQPSPDQS--GLDMTG- 174
+IS+ + N+++ + G N + D +S + S P S G G
Sbjct: 204 PSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGH 263
Query: 175 --IKQIKQEPIYDLTSVP-NLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTM 231
+ IK E TS P ++ YS ++ Q + + I + ++K + Q
Sbjct: 264 FPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTS---SPASIPHLILELLKCEPDEPQV-- 318
Query: 232 EELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQ 291
+ +A+ ++ S L + A Q +I VE+A+ F EL +DQ
Sbjct: 319 -QAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSI---VEWARSSIFFRELKVDDQ 374
Query: 292 ILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYG------GMQM-FKALGS------DDL 338
+ LL++ E++++ + + V+ GK G G Q+ + + S ++L
Sbjct: 375 MKLLQNCWSELLIL------DHIYRQVV-HGKEGSIFLVTGQQVDYSIIASQAGATLNNL 427
Query: 339 VNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQK 398
++ A + L SLQ + E VL S D L + V+ +QE++ AL
Sbjct: 428 MSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMC 487
Query: 399 NH-LDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPEI 437
N+ E +L+ ++P I A+ ++ E+ +K + ++
Sbjct: 488 NYPQQTEKFGQLLLRLPEIRAI-SMQAEEYLYYKHLNGDV 526
>gi|4504343 nuclear receptor subfamily 5, group A, member 2 isoform
2 [Homo sapiens]
Length = 495
Score = 127 bits (320), Expect = 2e-29
Identities = 124/460 (26%), Positives = 221/460 (48%), Gaps = 51/460 (11%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQK 69
C +CGDK SG HYG++TCE CKGFF+R+ QNN Y+C +NC ID+T R RC +CR QK
Sbjct: 40 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQK 99
Query: 70 CLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQ---QQSG-EAEALARVYSS- 124
CL++GM +AV+ RM + + + + K + L++Q++ + +G + EA+++V +
Sbjct: 100 CLSVGMKLEAVRADRM--RGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAM 157
Query: 125 ----SISNGLSNLNNETSGTYANGHVI---DLPKSEGYYNVDSGQPSPDQS--GLDMTG- 174
+IS+ + N+++ + G N + D +S + S P S G G
Sbjct: 158 PSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGH 217
Query: 175 --IKQIKQEPIYDLTSVP-NLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTM 231
+ IK E TS P ++ YS ++ Q + + I + ++K + Q
Sbjct: 218 FPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTS---SPASIPHLILELLKCEPDEPQV-- 272
Query: 232 EELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQ 291
+ +A+ ++ S L + A Q +I VE+A+ F EL +DQ
Sbjct: 273 -QAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSI---VEWARSSIFFRELKVDDQ 328
Query: 292 ILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYG------GMQM-FKALGS------DDL 338
+ LL++ E++++ + + V+ GK G G Q+ + + S ++L
Sbjct: 329 MKLLQNCWSELLIL------DHIYRQVV-HGKEGSIFLVTGQQVDYSIIASQAGATLNNL 381
Query: 339 VNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQK 398
++ A + L SLQ + E VL S D L + V+ +QE++ AL
Sbjct: 382 MSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMC 441
Query: 399 NH-LDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPEI 437
N+ E +L+ ++P I A+ ++ E+ +K + ++
Sbjct: 442 NYPQQTEKFGQLLLRLPEIRAI-SMQAEEYLYYKHLNGDV 480
>gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Homo
sapiens]
Length = 615
Score = 125 bits (314), Expect = 8e-29
Identities = 120/460 (26%), Positives = 209/460 (45%), Gaps = 57/460 (12%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQK 69
C +CGDK+SG HYG ++CEGCKGFF+RS + N +YSC ++C+I++ +RNRCQ CRL+K
Sbjct: 136 CVVCGDKASGRHYGAVSCEGCKGFFKRSVRKNLTYSCRSNQDCIINKHHRNRCQFCRLKK 195
Query: 70 CLALGMSRDAVKFGR----MSKKQRDSLYAEVQKHQQR--------------LQEQRQQQ 111
CL +GM ++V+ R + +++ + A +K R + +Q
Sbjct: 196 CLEMGMKMESVQSERKPFDVQREKPSNCAASTEKIYIRKDLRSPLIATPTFVADKDGARQ 255
Query: 112 SG--EAEALARVYSSSISNG-----LSNLNNETS----GTYANGHVIDLPKSEGYYNVDS 160
+G + L + I ++ ETS GT AN SE N D+
Sbjct: 256 TGLLDPGMLVNIQQPLIREDGTVLLATDSKAETSQGALGTLANVVTSLANLSESLNNGDT 315
Query: 161 GQPSP-DQSGLDMTGIKQIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMT---EIDRIA 216
+ P DQS ++T +D T L T S ++ LA GI + I I+
Sbjct: 316 SEIQPEDQSASEIT--------RAFD-TLAKALNTTDSSSSPSLADGIDTSGGGSIHVIS 366
Query: 217 QNIIKSHLETCQYTMEELH---QLAWQTHTYEEIKAY---QSKSREALWQQCAIQITHAI 270
++ +E + + H +L + E + + +S SR + A
Sbjct: 367 RDQSTPIIEVEGPLLSDTHVTFKLTMPSPMPEYLNVHYICESASRLLFLSMHWARSIPAF 426
Query: 271 QYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVR--MCRAFNPLNNTVLFEGKYGGMQ 328
Q + + T + C N+ L + C +V+ + + N L N++ E K G +
Sbjct: 427 QALGQDCN--TSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQ-EDKLSGDR 483
Query: 329 MFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKI 388
+ + + + + + +F ++ L + E A + VL SPD L +++K QEK
Sbjct: 484 IKQVM---EHIWKLQEFCNSMAKLDIDGYEYAYLKAIVLFSPDHPGLTSTSQIEKFQEKA 540
Query: 389 YFALQHVIQKNHLDDE-TLAKLIAKIPTITAVCNLHGEKL 427
LQ +QK + +D LA+++ ++P + + + E+L
Sbjct: 541 QMELQDYVQKTYSEDTYRLARILVRLPALRLMSSNITEEL 580
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 119 bits (298), Expect = 6e-27
Identities = 50/81 (61%), Positives = 63/81 (77%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQ 68
PC +C DKSSG HYGV +CEGCKGFFRRS Q N Y+C R +NC+I++ RNRCQ+CRLQ
Sbjct: 78 PCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 137
Query: 69 KCLALGMSRDAVKFGRMSKKQ 89
KC +GMS++AV+ R KK+
Sbjct: 138 KCFEVGMSKEAVRNDRNKKKK 158
Score = 92.8 bits (229), Expect = 6e-19
Identities = 71/246 (28%), Positives = 116/246 (47%), Gaps = 13/246 (5%)
Query: 211 EIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAI 270
+++ + + K+H ET L QL +T ++ + LW + + T I
Sbjct: 174 QLEELITKVSKAHQET----FPSLCQLG--KYTTNSSADHRVQLDLGLWDKFSELATKCI 227
Query: 271 QYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLF-EGKYGGMQM 329
+VEFAKR+ GF L DQI LLK+ CL+++++R+C + P +T+ F +G
Sbjct: 228 IKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQ 287
Query: 330 FKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIY 389
G L + F FA L L++ + E L S+ LI DR L EP KV KLQE +
Sbjct: 288 MHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLL 347
Query: 390 FALQ-HVIQKNHLDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKE 448
AL+ + ++ +++ KI + + E+ K P + PPL +E
Sbjct: 348 EALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPM----PPLIRE 403
Query: 449 LF-NPD 453
+ NP+
Sbjct: 404 MLENPE 409
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 119 bits (298), Expect = 6e-27
Identities = 50/81 (61%), Positives = 63/81 (77%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQ 68
PC +C DKSSG HYGV +CEGCKGFFRRS Q N Y+C R +NC+I++ RNRCQ+CRLQ
Sbjct: 89 PCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 148
Query: 69 KCLALGMSRDAVKFGRMSKKQ 89
KC +GMS++AV+ R KK+
Sbjct: 149 KCFEVGMSKEAVRNDRNKKKK 169
Score = 92.8 bits (229), Expect = 6e-19
Identities = 71/246 (28%), Positives = 116/246 (47%), Gaps = 13/246 (5%)
Query: 211 EIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAI 270
+++ + + K+H ET L QL +T ++ + LW + + T I
Sbjct: 185 QLEELITKVSKAHQET----FPSLCQLG--KYTTNSSADHRVQLDLGLWDKFSELATKCI 238
Query: 271 QYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLF-EGKYGGMQM 329
+VEFAKR+ GF L DQI LLK+ CL+++++R+C + P +T+ F +G
Sbjct: 239 IKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQ 298
Query: 330 FKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIY 389
G L + F FA L L++ + E L S+ LI DR L EP KV KLQE +
Sbjct: 299 MHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLL 358
Query: 390 FALQ-HVIQKNHLDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKE 448
AL+ + ++ +++ KI + + E+ K P + PPL +E
Sbjct: 359 EALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPM----PPLIRE 414
Query: 449 LF-NPD 453
+ NP+
Sbjct: 415 MLENPE 420
>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
Length = 448
Score = 117 bits (294), Expect = 2e-26
Identities = 50/84 (59%), Positives = 63/84 (75%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQ 68
PC +C DKSSG HYGV CEGCKGFFRRS Q N Y+C R +NC+I++ RNRCQ+CRLQ
Sbjct: 80 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQ 139
Query: 69 KCLALGMSRDAVKFGRMSKKQRDS 92
KC +GMS+++V+ R KK+ S
Sbjct: 140 KCFEVGMSKESVRNDRNKKKKETS 163
Score = 100 bits (249), Expect = 3e-21
Identities = 75/241 (31%), Positives = 116/241 (48%), Gaps = 12/241 (4%)
Query: 211 EIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAI 270
E+D + + I K+H ET L QL +T ++ + LW + + T I
Sbjct: 176 ELDDLTEKIRKAHQET----FPSLCQLG--KYTTNSSADHRVRLDLGLWDKFSELATKCI 229
Query: 271 QYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLF-EGKYGGMQM 329
+VEFAKR+ GF L DQI LLK+ CL+++++R+C + P +T+ F +G
Sbjct: 230 IKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQ 289
Query: 330 FKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIY 389
G L + F FA L L++ + E L S+ LI DR L EP KV KLQE +
Sbjct: 290 MHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLL 349
Query: 390 FALQHVIQKNH-LDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKE 448
AL+ I+K K++ KI + ++ E++ K P + PPL +E
Sbjct: 350 EALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSM----PPLIQE 405
Query: 449 L 449
+
Sbjct: 406 M 406
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 117 bits (292), Expect = 3e-26
Identities = 49/81 (60%), Positives = 62/81 (76%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQ 68
PC +C DKSSG HYGV CEGCKGFFRRS Q N Y+C R +NC+I++ RNRCQ+CRLQ
Sbjct: 87 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 146
Query: 69 KCLALGMSRDAVKFGRMSKKQ 89
KC +GMS+++V+ R KK+
Sbjct: 147 KCFEVGMSKESVRNDRNKKKK 167
Score = 87.4 bits (215), Expect = 2e-17
Identities = 68/241 (28%), Positives = 111/241 (46%), Gaps = 12/241 (4%)
Query: 211 EIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAI 270
E+ + + + K+H ET L QL +T + LW + + T I
Sbjct: 183 EVGELIEKVRKAHQET----FPALCQLG--KYTTNNSSEQRVSLDIDLWDKFSELSTKCI 236
Query: 271 QYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLF-EGKYGGMQM 329
VEFAK++ GF L DQI LLK+ CL+++++R+C + P +T+ F +G
Sbjct: 237 IKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQ 296
Query: 330 FKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIY 389
G L + F FA L L++ + E L S+ LI DR L +P +V LQE +
Sbjct: 297 MHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLL 356
Query: 390 FALQHVIQKNHLD-DETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKE 448
AL+ ++K K++ KI + ++ E++ K P + PPL +E
Sbjct: 357 EALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSM----PPLIQE 412
Query: 449 L 449
+
Sbjct: 413 M 413
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 117 bits (292), Expect = 3e-26
Identities = 49/81 (60%), Positives = 62/81 (76%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQ 68
PC +C DKSSG HYGV CEGCKGFFRRS Q N Y+C R +NC+I++ RNRCQ+CRLQ
Sbjct: 82 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 141
Query: 69 KCLALGMSRDAVKFGRMSKKQ 89
KC +GMS+++V+ R KK+
Sbjct: 142 KCFEVGMSKESVRNDRNKKKK 162
Score = 87.4 bits (215), Expect = 2e-17
Identities = 68/241 (28%), Positives = 111/241 (46%), Gaps = 12/241 (4%)
Query: 211 EIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAI 270
E+ + + + K+H ET L QL +T + LW + + T I
Sbjct: 178 EVGELIEKVRKAHQET----FPALCQLG--KYTTNNSSEQRVSLDIDLWDKFSELSTKCI 231
Query: 271 QYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLF-EGKYGGMQM 329
VEFAK++ GF L DQI LLK+ CL+++++R+C + P +T+ F +G
Sbjct: 232 IKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQ 291
Query: 330 FKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIY 389
G L + F FA L L++ + E L S+ LI DR L +P +V LQE +
Sbjct: 292 MHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLL 351
Query: 390 FALQHVIQKNHLD-DETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKE 448
AL+ ++K K++ KI + ++ E++ K P + PPL +E
Sbjct: 352 EALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSM----PPLIQE 407
Query: 449 L 449
+
Sbjct: 408 M 408
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 117 bits (292), Expect = 3e-26
Identities = 49/81 (60%), Positives = 62/81 (76%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQ 68
PC +C DKSSG HYGV CEGCKGFFRRS Q N Y+C R +NC+I++ RNRCQ+CRLQ
Sbjct: 87 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 146
Query: 69 KCLALGMSRDAVKFGRMSKKQ 89
KC +GMS+++V+ R KK+
Sbjct: 147 KCFEVGMSKESVRNDRNKKKK 167
Score = 87.4 bits (215), Expect = 2e-17
Identities = 68/241 (28%), Positives = 111/241 (46%), Gaps = 12/241 (4%)
Query: 211 EIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAI 270
E+ + + + K+H ET L QL +T + LW + + T I
Sbjct: 183 EVGELIEKVRKAHQET----FPALCQLG--KYTTNNSSEQRVSLDIDLWDKFSELSTKCI 236
Query: 271 QYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLF-EGKYGGMQM 329
VEFAK++ GF L DQI LLK+ CL+++++R+C + P +T+ F +G
Sbjct: 237 IKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQ 296
Query: 330 FKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIY 389
G L + F FA L L++ + E L S+ LI DR L +P +V LQE +
Sbjct: 297 MHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLL 356
Query: 390 FALQHVIQKNHLD-DETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKE 448
AL+ ++K K++ KI + ++ E++ K P + PPL +E
Sbjct: 357 EALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSM----PPLIQE 412
Query: 449 L 449
+
Sbjct: 413 M 413
>gi|53729327 nuclear receptor subfamily 6, group A, member 1 isoform
2 [Homo sapiens]
Length = 475
Score = 115 bits (288), Expect = 8e-26
Identities = 103/403 (25%), Positives = 173/403 (42%), Gaps = 59/403 (14%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQK 69
C ICGD+++G+HYG+I+CEGCKGFF+RS N Y C R +NC++ R RNRCQ+CRL K
Sbjct: 56 CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLK 115
Query: 70 CLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALARVYSSSISNG 129
CL +GM+R A++ M + S+ VQ ++ ++ Q E EA
Sbjct: 116 CLQMGMNRKAIREDGMPGGRNKSI-GPVQISEEEIERIMSGQEFEEEA------------ 162
Query: 130 LSNLNNETSGTYANGHVIDLPKSEGYYNVDSGQPSPDQS----GLDMTGIKQIKQE---- 181
N S + H S G +S QPSP + +++ G +++
Sbjct: 163 -----NHWSNHGDSDH-----SSPGNRASESNQPSPGSTLSSRSVELNGFMAFREQYMGM 212
Query: 182 ---PIYDLTSVPNLFTYSSFNN--GQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQ 236
P Y +P+LF+YS + Q A + I Q + LE M L +
Sbjct: 213 SVPPHYQY--IPHLFSYSGHSPLLPQQARSLDPQSYSLIHQLLSAEDLEPLGTPM--LIE 268
Query: 237 LAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLK 296
+ E + E L++Q A + K++ F EL D LL
Sbjct: 269 DGYAVTQAELFALLCRLADELLFRQIA------------WIKKLPFFCELSIKDYTCLLS 316
Query: 297 SGCLEVVLVRMCRAFNP------LNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLC 350
S E++L+ ++ + T + + F G + + + + K
Sbjct: 317 STWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHK-FH 375
Query: 351 SLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQ 393
L+++ EE A + ++ D L ++++L ++ ++ Q
Sbjct: 376 QLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQ 418
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 115 bits (287), Expect = 1e-25
Identities = 51/86 (59%), Positives = 64/86 (74%)
Query: 4 QIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQ 63
Q + I C +CGDKSSG HYG TCEGCK FF+RS + N SY+C RNC ID+ +RN+CQ
Sbjct: 73 QQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQ 132
Query: 64 HCRLQKCLALGMSRDAVKFGRMSKKQ 89
+CRL+KCL +GM R+AV+ GRM Q
Sbjct: 133 YCRLKKCLKVGMRREAVQRGRMPPTQ 158
Score = 42.7 bits (99), Expect = 7e-04
Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 4/158 (2%)
Query: 274 VEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEG---KYGGMQMF 330
VE+A+ I F +L DQ+ LL+ E+ ++ + PL+ L M
Sbjct: 224 VEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSAD 283
Query: 331 KALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYF 390
+ + D + + + L +L + E + + VL + D L + V+ LQEK
Sbjct: 284 RVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQC 343
Query: 391 ALQHVIQKNHLDDET-LAKLIAKIPTITAVCNLHGEKL 427
AL+ ++ + + T KL+ ++P++ V + E+L
Sbjct: 344 ALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQL 381
>gi|53729325 nuclear receptor subfamily 6, group A, member 1 isoform
1 [Homo sapiens]
Length = 480
Score = 115 bits (287), Expect = 1e-25
Identities = 103/404 (25%), Positives = 173/404 (42%), Gaps = 60/404 (14%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQK 69
C ICGD+++G+HYG+I+CEGCKGFF+RS N Y C R +NC++ R RNRCQ+CRL K
Sbjct: 60 CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLK 119
Query: 70 CLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALARVYSSSISNG 129
CL +GM+R A++ M + S+ VQ ++ ++ Q E EA
Sbjct: 120 CLQMGMNRKAIREDGMPGGRNKSI-GPVQISEEEIERIMSGQEFEEEA------------ 166
Query: 130 LSNLNNETSGTYANGHVIDLPKSEGYYNVDSGQPSPDQS-----GLDMTGIKQIKQE--- 181
N S + H S G +S QPSP + +++ G +++
Sbjct: 167 -----NHWSNHGDSDH-----SSPGNRASESNQPSPGSTLSSSRSVELNGFMAFREQYMG 216
Query: 182 ----PIYDLTSVPNLFTYSSFNN--GQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELH 235
P Y +P+LF+YS + Q A + I Q + LE M L
Sbjct: 217 MSVPPHYQY--IPHLFSYSGHSPLLPQQARSLDPQSYSLIHQLLSAEDLEPLGTPM--LI 272
Query: 236 QLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLL 295
+ + E + E L++Q A + K++ F EL D LL
Sbjct: 273 EDGYAVTQAELFALLCRLADELLFRQIA------------WIKKLPFFCELSIKDYTCLL 320
Query: 296 KSGCLEVVLVRMCRAFNP------LNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNL 349
S E++L+ ++ + T + + F G + + + + K
Sbjct: 321 SSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHK-F 379
Query: 350 CSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQ 393
L+++ EE A + ++ D L ++++L ++ ++ Q
Sbjct: 380 HQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQ 423
>gi|50348666 peroxisome proliferative activated receptor, alpha
[Homo sapiens]
Length = 468
Score = 114 bits (285), Expect = 2e-25
Identities = 57/144 (39%), Positives = 90/144 (62%), Gaps = 7/144 (4%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRL 67
I C+ICGDK+SG HYGV CEGCKGFFRR+ + Y R+C I + NRN+CQ+CR
Sbjct: 100 IECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYD-KCDRSCKIQKKNRNKCQYCRF 158
Query: 68 QKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALA-RVYSSSI 126
KCL++GMS +A++FGRM + ++ L AE+ + +++ ++ + ++LA R+Y + +
Sbjct: 159 HKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIED---SETADLKSLAKRIYEAYL 215
Query: 127 SNGLSNLNNETSGTYANGHVIDLP 150
N N+N + +G + P
Sbjct: 216 KN--FNMNKVKARVILSGKASNNP 237
Score = 89.7 bits (221), Expect = 5e-18
Identities = 57/205 (27%), Positives = 102/205 (49%), Gaps = 5/205 (2%)
Query: 251 QSKSREA-LWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCR 309
Q+K E ++ C + + EFAK I GF L NDQ+ LLK G E + +
Sbjct: 264 QNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSS 323
Query: 310 AFNPLNNTVLFEGKYGGMQMFKALGSD--DLVNEAFDFAKNLCSLQLTEEEIALFSSAVL 367
N V + + + K+L D++ FDFA +L+L + +I+LF +A++
Sbjct: 324 VMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAII 383
Query: 368 ISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETL-AKLIAKIPTITAVCNLHGEK 426
DR L+ ++K+QE I L+ +Q NH DD L KL+ K+ + + H +
Sbjct: 384 CCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQL 443
Query: 427 LQVFKQSHPE-IVNTLFPPLYKELF 450
+Q+ K++ + ++ L +Y++++
Sbjct: 444 VQIIKKTESDAALHPLLQEIYRDMY 468
>gi|7549811 peroxisome proliferative activated receptor, alpha [Homo
sapiens]
Length = 468
Score = 114 bits (285), Expect = 2e-25
Identities = 57/144 (39%), Positives = 90/144 (62%), Gaps = 7/144 (4%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRL 67
I C+ICGDK+SG HYGV CEGCKGFFRR+ + Y R+C I + NRN+CQ+CR
Sbjct: 100 IECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYD-KCDRSCKIQKKNRNKCQYCRF 158
Query: 68 QKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALA-RVYSSSI 126
KCL++GMS +A++FGRM + ++ L AE+ + +++ ++ + ++LA R+Y + +
Sbjct: 159 HKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIED---SETADLKSLAKRIYEAYL 215
Query: 127 SNGLSNLNNETSGTYANGHVIDLP 150
N N+N + +G + P
Sbjct: 216 KN--FNMNKVKARVILSGKASNNP 237
Score = 89.7 bits (221), Expect = 5e-18
Identities = 57/205 (27%), Positives = 102/205 (49%), Gaps = 5/205 (2%)
Query: 251 QSKSREA-LWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCR 309
Q+K E ++ C + + EFAK I GF L NDQ+ LLK G E + +
Sbjct: 264 QNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSS 323
Query: 310 AFNPLNNTVLFEGKYGGMQMFKALGSD--DLVNEAFDFAKNLCSLQLTEEEIALFSSAVL 367
N V + + + K+L D++ FDFA +L+L + +I+LF +A++
Sbjct: 324 VMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAII 383
Query: 368 ISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETL-AKLIAKIPTITAVCNLHGEK 426
DR L+ ++K+QE I L+ +Q NH DD L KL+ K+ + + H +
Sbjct: 384 CCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQL 443
Query: 427 LQVFKQSHPE-IVNTLFPPLYKELF 450
+Q+ K++ + ++ L +Y++++
Sbjct: 444 VQIIKKTESDAALHPLLQEIYRDMY 468
>gi|116284373 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 114 bits (285), Expect = 2e-25
Identities = 57/123 (46%), Positives = 81/123 (65%), Gaps = 8/123 (6%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYS-CPRQRNCLIDRTNRNRCQHCR 66
I C++CGDK+SG HYGV CEGCKGFFRR+ + Y C NC I + +RN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 166
Query: 67 LQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALAR-VYSSS 125
QKCLA+GMS +A++FGRM + +++ L AE+ +Q +S + ALA+ +Y S
Sbjct: 167 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSD----IDQLNPESADLRALAKHLYDSY 222
Query: 126 ISN 128
I +
Sbjct: 223 IKS 225
Score = 97.1 bits (240), Expect = 3e-20
Identities = 59/215 (27%), Positives = 118/215 (54%), Gaps = 9/215 (4%)
Query: 244 YEEIKAYQSKSREA---LWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCL 300
++ I Q +S+E ++Q C + A+Q + E+AK I GF+ L NDQ+ LLK G
Sbjct: 264 FKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVH 323
Query: 301 EVVLVRMCRAFNPLNNTVLFEGK-YGGMQMFKALGS--DDLVNEAFDFAKNLCSLQLTEE 357
E++ + N + ++ EG+ + + K+L D + F+FA +L+L +
Sbjct: 324 EIIYTMLASLMNK-DGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDS 382
Query: 358 EIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETL-AKLIAKIPTI 416
++A+F + +++S DR L+ + ++ +Q+ + AL+ ++ NH + L AKL+ K+ +
Sbjct: 383 DLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDL 442
Query: 417 TAVCNLHGEKLQVFKQSHPEI-VNTLFPPLYKELF 450
+ H + LQV K++ ++ ++ L +YK+L+
Sbjct: 443 RQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477
>gi|20336229 peroxisome proliferative activated receptor gamma
isoform 2 [Homo sapiens]
Length = 505
Score = 114 bits (285), Expect = 2e-25
Identities = 57/123 (46%), Positives = 81/123 (65%), Gaps = 8/123 (6%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYS-CPRQRNCLIDRTNRNRCQHCR 66
I C++CGDK+SG HYGV CEGCKGFFRR+ + Y C NC I + +RN+CQ+CR
Sbjct: 137 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 194
Query: 67 LQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALAR-VYSSS 125
QKCLA+GMS +A++FGRM + +++ L AE+ +Q +S + ALA+ +Y S
Sbjct: 195 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSD----IDQLNPESADLRALAKHLYDSY 250
Query: 126 ISN 128
I +
Sbjct: 251 IKS 253
Score = 97.1 bits (240), Expect = 3e-20
Identities = 59/215 (27%), Positives = 118/215 (54%), Gaps = 9/215 (4%)
Query: 244 YEEIKAYQSKSREA---LWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCL 300
++ I Q +S+E ++Q C + A+Q + E+AK I GF+ L NDQ+ LLK G
Sbjct: 292 FKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVH 351
Query: 301 EVVLVRMCRAFNPLNNTVLFEGK-YGGMQMFKALGS--DDLVNEAFDFAKNLCSLQLTEE 357
E++ + N + ++ EG+ + + K+L D + F+FA +L+L +
Sbjct: 352 EIIYTMLASLMNK-DGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDS 410
Query: 358 EIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETL-AKLIAKIPTI 416
++A+F + +++S DR L+ + ++ +Q+ + AL+ ++ NH + L AKL+ K+ +
Sbjct: 411 DLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDL 470
Query: 417 TAVCNLHGEKLQVFKQSHPEI-VNTLFPPLYKELF 450
+ H + LQV K++ ++ ++ L +YK+L+
Sbjct: 471 RQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 505
>gi|116284368 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 114 bits (285), Expect = 2e-25
Identities = 57/123 (46%), Positives = 81/123 (65%), Gaps = 8/123 (6%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYS-CPRQRNCLIDRTNRNRCQHCR 66
I C++CGDK+SG HYGV CEGCKGFFRR+ + Y C NC I + +RN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 166
Query: 67 LQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALAR-VYSSS 125
QKCLA+GMS +A++FGRM + +++ L AE+ +Q +S + ALA+ +Y S
Sbjct: 167 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSD----IDQLNPESADLRALAKHLYDSY 222
Query: 126 ISN 128
I +
Sbjct: 223 IKS 225
Score = 97.1 bits (240), Expect = 3e-20
Identities = 59/215 (27%), Positives = 118/215 (54%), Gaps = 9/215 (4%)
Query: 244 YEEIKAYQSKSREA---LWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCL 300
++ I Q +S+E ++Q C + A+Q + E+AK I GF+ L NDQ+ LLK G
Sbjct: 264 FKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVH 323
Query: 301 EVVLVRMCRAFNPLNNTVLFEGK-YGGMQMFKALGS--DDLVNEAFDFAKNLCSLQLTEE 357
E++ + N + ++ EG+ + + K+L D + F+FA +L+L +
Sbjct: 324 EIIYTMLASLMNK-DGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDS 382
Query: 358 EIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETL-AKLIAKIPTI 416
++A+F + +++S DR L+ + ++ +Q+ + AL+ ++ NH + L AKL+ K+ +
Sbjct: 383 DLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDL 442
Query: 417 TAVCNLHGEKLQVFKQSHPEI-VNTLFPPLYKELF 450
+ H + LQV K++ ++ ++ L +YK+L+
Sbjct: 443 RQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477
>gi|116284370 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 114 bits (285), Expect = 2e-25
Identities = 57/123 (46%), Positives = 81/123 (65%), Gaps = 8/123 (6%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYS-CPRQRNCLIDRTNRNRCQHCR 66
I C++CGDK+SG HYGV CEGCKGFFRR+ + Y C NC I + +RN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 166
Query: 67 LQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALAR-VYSSS 125
QKCLA+GMS +A++FGRM + +++ L AE+ +Q +S + ALA+ +Y S
Sbjct: 167 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSD----IDQLNPESADLRALAKHLYDSY 222
Query: 126 ISN 128
I +
Sbjct: 223 IKS 225
Score = 97.1 bits (240), Expect = 3e-20
Identities = 59/215 (27%), Positives = 118/215 (54%), Gaps = 9/215 (4%)
Query: 244 YEEIKAYQSKSREA---LWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCL 300
++ I Q +S+E ++Q C + A+Q + E+AK I GF+ L NDQ+ LLK G
Sbjct: 264 FKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVH 323
Query: 301 EVVLVRMCRAFNPLNNTVLFEGK-YGGMQMFKALGS--DDLVNEAFDFAKNLCSLQLTEE 357
E++ + N + ++ EG+ + + K+L D + F+FA +L+L +
Sbjct: 324 EIIYTMLASLMNK-DGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDS 382
Query: 358 EIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETL-AKLIAKIPTI 416
++A+F + +++S DR L+ + ++ +Q+ + AL+ ++ NH + L AKL+ K+ +
Sbjct: 383 DLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDL 442
Query: 417 TAVCNLHGEKLQVFKQSHPEI-VNTLFPPLYKELF 450
+ H + LQV K++ ++ ++ L +YK+L+
Sbjct: 443 RQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 113 bits (283), Expect = 3e-25
Identities = 49/82 (59%), Positives = 62/82 (75%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRL 67
I C +CGDKSSG HYG TCEGCK FF+RS + N +Y+C RNC ID+ +RN+CQ+CRL
Sbjct: 84 IECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRL 143
Query: 68 QKCLALGMSRDAVKFGRMSKKQ 89
+KCL +GM R+AV+ GRM Q
Sbjct: 144 KKCLKVGMRREAVQRGRMPPTQ 165
Score = 40.8 bits (94), Expect = 0.003
Identities = 35/158 (22%), Positives = 71/158 (44%), Gaps = 4/158 (2%)
Query: 274 VEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEG---KYGGMQMF 330
VE+A+ I F +L DQ+ LL+ E+ ++ + PL+ L M
Sbjct: 231 VEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSAD 290
Query: 331 KALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYF 390
+ + D + + + L +L + E + + VL + D L + ++ LQEK
Sbjct: 291 RVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQC 350
Query: 391 ALQHVIQKNHLDDET-LAKLIAKIPTITAVCNLHGEKL 427
AL+ ++ + + + KL+ ++P++ V + E+L
Sbjct: 351 ALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQL 388
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 112 bits (281), Expect = 5e-25
Identities = 52/107 (48%), Positives = 73/107 (68%), Gaps = 2/107 (1%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQK 69
C ICGD+SSG HYGV +CEGCKGFF+R+ + + +Y+C ++CLID+ RNRCQ+CR QK
Sbjct: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194
Query: 70 CLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAE 116
CLA+GM R+AV+ R K R+ EV+ ++ ++ EAE
Sbjct: 195 CLAMGMKREAVQEERQRGKDRNE--NEVESTSSANEDMPVERILEAE 239
Score = 57.8 bits (138), Expect = 2e-08
Identities = 38/153 (24%), Positives = 76/153 (49%), Gaps = 9/153 (5%)
Query: 273 VVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKA 332
+VE+AKRI F EL +DQ++LL++G E+++ + + +L G+ + +
Sbjct: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLAT---GLHVHRN 335
Query: 333 LGSDDLVNEAFD-----FAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEK 387
V FD + +Q+ + E+ + VL +PD L P +V+ L+EK
Sbjct: 336 SAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREK 395
Query: 388 IYFALQHVIQKNHLDDE-TLAKLIAKIPTITAV 419
+Y +L+ + + + AKL+ ++P + ++
Sbjct: 396 VYASLEAYCKHKYPEQPGRFAKLLLRLPALRSI 428
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,272,494
Number of Sequences: 37866
Number of extensions: 756906
Number of successful extensions: 4059
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 3637
Number of HSP's gapped (non-prelim): 324
length of query: 459
length of database: 18,247,518
effective HSP length: 106
effective length of query: 353
effective length of database: 14,233,722
effective search space: 5024503866
effective search space used: 5024503866
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.