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Search of human proteins with 19743898
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19743898 receptor tyrosine kinase-like orphan receptor 2
precursor [Homo sapiens]
(943 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19743898 receptor tyrosine kinase-like orphan receptor 2 prec... 1950 0.0
gi|134152725 receptor tyrosine kinase-like orphan receptor 1 iso... 1070 0.0
gi|134152686 receptor tyrosine kinase-like orphan receptor 1 iso... 520 e-147
gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens] 301 2e-81
gi|65506745 neurotrophic tyrosine kinase, receptor, type 2 isofo... 246 7e-65
gi|21361306 neurotrophic tyrosine kinase, receptor, type 2 isofo... 246 7e-65
gi|59889560 neurotrophic tyrosine kinase, receptor, type 3 isofo... 246 9e-65
gi|59889562 neurotrophic tyrosine kinase, receptor, type 3 isofo... 239 1e-62
gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isofo... 238 2e-62
gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isofor... 238 2e-62
gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isofo... 238 2e-62
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 206 1e-52
gi|119395738 insulin receptor isoform Short precursor [Homo sapi... 205 2e-52
gi|119395736 insulin receptor isoform Long precursor [Homo sapiens] 205 2e-52
gi|62420886 discoidin domain receptor family, member 2 precursor... 204 2e-52
gi|62420884 discoidin domain receptor family, member 2 precursor... 204 2e-52
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 204 3e-52
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 203 5e-52
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 202 9e-52
gi|47524177 fibroblast growth factor receptor 4 isoform 2 precur... 201 3e-51
gi|47524175 fibroblast growth factor receptor 4 isoform 1 precur... 201 3e-51
gi|47524173 fibroblast growth factor receptor 4 isoform 1 precur... 201 3e-51
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 199 1e-50
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 198 2e-50
gi|38327632 discoidin domain receptor family, member 1 isoform b... 198 2e-50
gi|83977450 discoidin domain receptor family, member 1 isoform a... 198 2e-50
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 197 3e-50
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 197 3e-50
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 197 4e-50
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 197 5e-50
>gi|19743898 receptor tyrosine kinase-like orphan receptor 2
precursor [Homo sapiens]
Length = 943
Score = 1950 bits (5051), Expect = 0.0
Identities = 943/943 (100%), Positives = 943/943 (100%)
Query: 1 MARGSALPRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGY 60
MARGSALPRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGY
Sbjct: 1 MARGSALPRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGY 60
Query: 61 FLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRL 120
FLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRL
Sbjct: 61 FLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRL 120
Query: 121 RIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGI 180
RIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGI
Sbjct: 121 RIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGI 180
Query: 181 ACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCD 240
ACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCD
Sbjct: 181 ACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCD 240
Query: 241 ARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANC 300
ARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANC
Sbjct: 241 ARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANC 300
Query: 301 MRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGG 360
MRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGG
Sbjct: 301 MRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGG 360
Query: 361 GHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVPSIAIPLVIAC 420
GHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVPSIAIPLVIAC
Sbjct: 361 GHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVPSIAIPLVIAC 420
Query: 421 LFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRFMEELG 480
LFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRFMEELG
Sbjct: 421 LFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRFMEELG 480
Query: 481 EDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLL 540
EDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLL
Sbjct: 481 EDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLL 540
Query: 541 GVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIA 600
GVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIA
Sbjct: 541 GVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIA 600
Query: 601 AGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMA 660
AGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMA
Sbjct: 601 AGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMA 660
Query: 661 PEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAW 720
PEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAW
Sbjct: 661 PEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAW 720
Query: 721 VYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSN 780
VYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSN
Sbjct: 721 VYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSN 780
Query: 781 VSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAYGAYLPNFYPV 840
VSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAYGAYLPNFYPV
Sbjct: 781 VSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAYGAYLPNFYPV 840
Query: 841 QIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNA 900
QIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNA
Sbjct: 841 QIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNA 900
Query: 901 PEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA 943
PEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
Sbjct: 901 PEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA 943
>gi|134152725 receptor tyrosine kinase-like orphan receptor 1
isoform 1 [Homo sapiens]
Length = 937
Score = 1070 bits (2766), Expect = 0.0
Identities = 531/884 (60%), Positives = 656/884 (74%), Gaps = 20/884 (2%)
Query: 8 PRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGYFLNFLEP 67
PRR P + AALLL+ + + L + L P + K +L EP
Sbjct: 4 PRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEP 63
Query: 68 VNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDT 127
+NNIT GQTA LHCKV+GNPPP +RW KNDAPVVQEPRR+ R T YGSRLRI++LDT
Sbjct: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT 123
Query: 128 TDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGIACARFIG 187
TDTGY+QCVATNG + +++TGVLFV+ GP + + + D+Y EDGFCQPYRGIACARFIG
Sbjct: 124 TDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACARFIG 183
Query: 188 NRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCDARSRTPK 247
NRT+Y++SL MQGEIEN+ITAAFTMIGTS+HLSD+CSQFAIPS CH+ FP CD S PK
Sbjct: 184 NRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPK 243
Query: 248 PRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANCMRIGIP- 306
PR+LCRDECE+LE+ LC+ EY ARSNP+ILMRL+LP CE LP PESP+AANC+RIGIP
Sbjct: 244 PRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPM 303
Query: 307 AERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCR 366
A+ + + H+CYN +G+DYRGT S TKSG QCQPW Q+PH+H ++ FPEL GGH+YCR
Sbjct: 304 ADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCR 363
Query: 367 NPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDS---SKMGILYILVPSIAIPLVIACLFF 423
NPG Q E PWCFT ++N + +LCD+P+C +DS +KM ILYILVPS+AIPL IA LFF
Sbjct: 364 NPGNQKEAPWCFTLDENFKSDLCDIPACDSKDSKEKNKMEILYILVPSVAIPLAIALLFF 423
Query: 424 LVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHK-QAKLKEISLSAVRFMEELGED 482
+C+CRN QK S+S P +RQ Q++EM ++N +K ++K KE+ LSAVRFMEELGE
Sbjct: 424 FICVCRNNQK-SSSAPVQRQPKHVRGQNVEMSMLNAYKPKSKAKELPLSAVRFMEELGEC 482
Query: 483 RFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGV 542
FGK+YKGHL+ P + Q VAIKTLKD EF+ EA L A L HPN+VCLLG
Sbjct: 483 AFGKIYKGHLYLPGM-DHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGA 541
Query: 543 VTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVG-STDDDRTVKSALEPPDFVHLVAQIAA 601
VT++QP+ M+F Y + GDLHEFL+MRSPHSDVG S+D+D TVKS+L+ DF+H+ QIAA
Sbjct: 542 VTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAA 601
Query: 602 GMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMAP 661
GMEYLSSH VHKDLA RN+L+ ++L+VKISDLGL RE+Y+ADYY++ SLLPIRWM P
Sbjct: 602 GMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSLLPIRWMPP 661
Query: 662 EAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWV 721
EAIMYGKFS DSDIWS+GVVLWE+FS+GLQPY G+SNQ+V+EM+R RQ+LPC +DCP +
Sbjct: 662 EAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRM 721
Query: 722 YALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSNV 781
Y+LM ECWNE PSRRPRFKDIH RLR+W LS++ SS SG + TTQT+SLS SPVSN+
Sbjct: 722 YSLMTECWNEIPSRRPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLSASPVSNL 781
Query: 782 SNAR---YVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAYGAYLPNFY 838
SN R Y+ P Q P Q + G I P +P Q ++P+NGY P Y A+ Y
Sbjct: 782 SNPRYPNYMFPSQGITPQGQ-----IAGFIGPPIPQNQRFIPINGYPIPPGYAAFPAAHY 836
Query: 839 PVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTS 882
P ++ Q PP PK S S SGSTSTG+VT+ PS+ S
Sbjct: 837 QPTGPPRVI-QHCPP---PKSRSPSSASGSTSTGHVTSLPSSGS 876
>gi|134152686 receptor tyrosine kinase-like orphan receptor 1
isoform 2 [Homo sapiens]
Length = 393
Score = 520 bits (1338), Expect = e-147
Identities = 240/388 (61%), Positives = 295/388 (76%), Gaps = 1/388 (0%)
Query: 8 PRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGYFLNFLEP 67
PRR P + AALLL+ + + L + L P + K +L EP
Sbjct: 4 PRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEP 63
Query: 68 VNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDT 127
+NNIT GQTA LHCKV+GNPPP +RW KNDAPVVQEPRR+ R T YGSRLRI++LDT
Sbjct: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT 123
Query: 128 TDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGIACARFIG 187
TDTGY+QCVATNG + +++TGVLFV+ GP + + + D+Y EDGFCQPYRGIACARFIG
Sbjct: 124 TDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACARFIG 183
Query: 188 NRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCDARSRTPK 247
NRT+Y++SL MQGEIEN+ITAAFTMIGTS+HLSD+CSQFAIPS CH+ FP CD S PK
Sbjct: 184 NRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPK 243
Query: 248 PRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANCMRIGIP- 306
PR+LCRDECE+LE+ LC+ EY ARSNP+ILMRL+LP CE LP PESP+AANC+RIGIP
Sbjct: 244 PRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPM 303
Query: 307 AERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCR 366
A+ + + H+CYN +G+DYRGT S TKSG QCQPW Q+PH+H ++ FPEL GGH+YCR
Sbjct: 304 ADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCR 363
Query: 367 NPGGQMEGPWCFTQNKNVRMELCDVPSC 394
NPG Q E PWCFT ++N + +LCD+P+C
Sbjct: 364 NPGNQKEAPWCFTLDENFKSDLCDIPAC 391
>gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]
Length = 869
Score = 301 bits (771), Expect = 2e-81
Identities = 206/725 (28%), Positives = 321/725 (44%), Gaps = 99/725 (13%)
Query: 61 FLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRL 120
F L + + G LHC G P P + W++N V + ++ SRL
Sbjct: 211 FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL 270
Query: 121 RIQDLDTTDTGYYQCVATN--GMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYR 178
+ L T G Y C+ATN G K TA + + P + G+C YR
Sbjct: 271 Q---LFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKD------NKGYCAQYR 321
Query: 179 GIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPL 238
G C + + + E + T +S C A C+ +F
Sbjct: 322 GEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQE 381
Query: 239 CDARSRTPKPRELCRDECEVLESDLCRQEYTIARSNP------LILMRLQLPKCEALPMP 292
C P P +CR+ C ++ C +E+ + + L +P+C LP
Sbjct: 382 CSP-GVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSM 440
Query: 293 ESPDAANCMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSS 352
D C R+ H YN + +++K S
Sbjct: 441 HW-DPTACARLP---------HLDYNKENLKTFPPMTSSKP------------------S 472
Query: 353 TDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVPSI 412
D P L + S S + M ++ ++ S
Sbjct: 473 VDIPNLPSSSS----------------------------SSFSVSPTYSMTVIISIMSSF 504
Query: 413 AIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDM-----------EMPLINQHK 461
AI +++ C R + K L PS+ + MPL+ K
Sbjct: 505 AIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPK 564
Query: 462 QAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEF 521
L E + + ++ ++GE FG+V++ G P E VA+K LK++A ++ +F
Sbjct: 565 LLSL-EYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADF 623
Query: 522 RHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDR 581
+ EA L A +PN+V LLGV +P+ ++F Y ++GDL+EFL SPH+ + D
Sbjct: 624 QREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDL 683
Query: 582 TVKSALEPP--------DFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISD 633
++++ + P + + + Q+AAGM YLS VH+DLATRN LV + + VKI+D
Sbjct: 684 SMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIAD 743
Query: 634 LGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPY 693
GL R +Y+ADYYK N +PIRWM PE+I Y +++ +SD+W+YGVVLWE+FSYGLQPY
Sbjct: 744 FGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPY 803
Query: 694 CGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRL-----RA 748
G ++++V+ +R+ +L CP++CP +Y LM CW++ P+ RP F IH L RA
Sbjct: 804 YGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRILERMCERA 863
Query: 749 WGNLS 753
G +S
Sbjct: 864 EGTVS 868
Score = 62.4 bits (150), Expect = 2e-09
Identities = 31/77 (40%), Positives = 46/77 (59%), Gaps = 4/77 (5%)
Query: 67 PVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLD 126
P N+ I++G A+L C GNP P+V W+K D+P+ + R ++ E GS LRI ++
Sbjct: 126 PPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVL---ESGS-LRIHNVQ 181
Query: 127 TTDTGYYQCVATNGMKT 143
D G Y+CVA N + T
Sbjct: 182 KEDAGQYRCVAKNSLGT 198
Score = 43.5 bits (101), Expect = 0.001
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 67 PVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLD 126
P+ + + + A C V P P + W +N + R IR E G L I ++
Sbjct: 33 PLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIR--ENGQLLTILSVE 90
Query: 127 TTDTGYYQCVATNGM-KTITATGVLFVRLGP 156
+D G Y C A NG+ + + G L V++ P
Sbjct: 91 DSDDGIYCCTANNGVGGAVESCGALQVKMKP 121
>gi|65506745 neurotrophic tyrosine kinase, receptor, type 2 isoform
c precursor [Homo sapiens]
Length = 822
Score = 246 bits (628), Expect = 7e-65
Identities = 125/270 (46%), Positives = 169/270 (62%), Gaps = 4/270 (1%)
Query: 478 ELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVV 537
ELGE FGKV+ + P + VA+KTLKD ++ R++F EA L LQH ++V
Sbjct: 543 ELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNA-RKDFHREAELLTNLQHEHIV 601
Query: 538 CLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVA 597
GV + PL M+F Y HGDL++FL P + + + + T L +H+
Sbjct: 602 KFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPT---ELTQSQMLHIAQ 658
Query: 598 QIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIR 657
QIAAGM YL+S H VH+DLATRN LV + L VKI D G+ R+VY+ DYY++ G+++LPIR
Sbjct: 659 QIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIR 718
Query: 658 WMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDC 717
WM PE+IMY KF+ +SD+WS GVVLWE+F+YG QP+ SN +V+E I +VL P C
Sbjct: 719 WMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTC 778
Query: 718 PAWVYALMIECWNEFPSRRPRFKDIHSRLR 747
P VY LM+ CW P R K IH+ L+
Sbjct: 779 PQEVYELMLGCWQREPHMRKNIKGIHTLLQ 808
Score = 39.3 bits (90), Expect = 0.017
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 9/109 (8%)
Query: 70 NITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTD 129
N+T+ +G++ L C VAG+P PN+ W V + + + LRI ++ + D
Sbjct: 205 NLTVEEGKSITLSCSVAGDPVPNMYW-----DVGNLVSKHMNETSHTQGSLRITNISSDD 259
Query: 130 TG-YYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPY 177
+G CVA N + + L V PT + + D+H +C P+
Sbjct: 260 SGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH---WCIPF 305
Score = 30.4 bits (67), Expect = 8.1
Identities = 29/112 (25%), Positives = 46/112 (41%), Gaps = 12/112 (10%)
Query: 71 ITIVQGQTAILHC----KVAGNPPPNVRWLKNDAPVVQEPRRI-----IIRKTEYGSRLR 121
IT ++ T+ H V GNP P ++W N A ++ E + I + TEY L+
Sbjct: 289 ITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGA-ILNESKYICTKIHVTNHTEYHGCLQ 347
Query: 122 IQDLDTTDTGYYQCVATN--GMKTITATGVLFVRLGPTHSPNHNFQDDYHED 171
+ + + G Y +A N G + G N N+ D +ED
Sbjct: 348 LDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYED 399
>gi|21361306 neurotrophic tyrosine kinase, receptor, type 2 isoform
a precursor [Homo sapiens]
Length = 838
Score = 246 bits (628), Expect = 7e-65
Identities = 125/270 (46%), Positives = 169/270 (62%), Gaps = 4/270 (1%)
Query: 478 ELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVV 537
ELGE FGKV+ + P + VA+KTLKD ++ R++F EA L LQH ++V
Sbjct: 559 ELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNA-RKDFHREAELLTNLQHEHIV 617
Query: 538 CLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVA 597
GV + PL M+F Y HGDL++FL P + + + + T L +H+
Sbjct: 618 KFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPT---ELTQSQMLHIAQ 674
Query: 598 QIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIR 657
QIAAGM YL+S H VH+DLATRN LV + L VKI D G+ R+VY+ DYY++ G+++LPIR
Sbjct: 675 QIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIR 734
Query: 658 WMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDC 717
WM PE+IMY KF+ +SD+WS GVVLWE+F+YG QP+ SN +V+E I +VL P C
Sbjct: 735 WMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTC 794
Query: 718 PAWVYALMIECWNEFPSRRPRFKDIHSRLR 747
P VY LM+ CW P R K IH+ L+
Sbjct: 795 PQEVYELMLGCWQREPHMRKNIKGIHTLLQ 824
Score = 39.3 bits (90), Expect = 0.017
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 9/109 (8%)
Query: 70 NITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTD 129
N+T+ +G++ L C VAG+P PN+ W V + + + LRI ++ + D
Sbjct: 205 NLTVEEGKSITLSCSVAGDPVPNMYW-----DVGNLVSKHMNETSHTQGSLRITNISSDD 259
Query: 130 TG-YYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPY 177
+G CVA N + + L V PT + + D+H +C P+
Sbjct: 260 SGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH---WCIPF 305
Score = 30.4 bits (67), Expect = 8.1
Identities = 29/112 (25%), Positives = 46/112 (41%), Gaps = 12/112 (10%)
Query: 71 ITIVQGQTAILHC----KVAGNPPPNVRWLKNDAPVVQEPRRI-----IIRKTEYGSRLR 121
IT ++ T+ H V GNP P ++W N A ++ E + I + TEY L+
Sbjct: 289 ITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGA-ILNESKYICTKIHVTNHTEYHGCLQ 347
Query: 122 IQDLDTTDTGYYQCVATN--GMKTITATGVLFVRLGPTHSPNHNFQDDYHED 171
+ + + G Y +A N G + G N N+ D +ED
Sbjct: 348 LDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYED 399
>gi|59889560 neurotrophic tyrosine kinase, receptor, type 3 isoform
b precursor [Homo sapiens]
Length = 825
Score = 246 bits (627), Expect = 9e-65
Identities = 127/294 (43%), Positives = 176/294 (59%), Gaps = 2/294 (0%)
Query: 458 NQHK-QAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGP 516
N HK ++ I + ELGE FGKV+ + +P + VA+K LKD
Sbjct: 522 NCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAA 581
Query: 517 LREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGS 576
R++F+ EA L LQH ++V GV PL M+F Y HGDL++FL P + +
Sbjct: 582 -RKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILV 640
Query: 577 TDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGL 636
R K L +H+ +QIA+GM YL+S H VH+DLATRN LV L VKI D G+
Sbjct: 641 DGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGM 700
Query: 637 FREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGY 696
R+VY+ DYY++ G+++LPIRWM PE+IMY KF+ +SD+WS+GV+LWE+F+YG QP+
Sbjct: 701 SRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQL 760
Query: 697 SNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWG 750
SN +V+E I +VL P CP VY +M+ CW P +R K+I+ L A G
Sbjct: 761 SNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALG 814
Score = 35.8 bits (81), Expect = 0.19
Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Query: 70 NITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTD 129
N+T+ +G A++ C +G+P P+V W+ + + + + L + ++ + D
Sbjct: 218 NLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSED 277
Query: 130 TGY-YQCVATNGMKTITATGVLFVRLGP 156
G+ C+A N + A+ L V P
Sbjct: 278 NGFTLTCIAENVVGMSNASVALTVYYPP 305
Score = 31.6 bits (70), Expect = 3.6
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
Query: 67 PVNNITIVQGQTAILHC---KVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYG----SR 119
P +++ + + + HC V GNPPP + WL N P ++E + I + + G
Sbjct: 304 PPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQP-LRESKIIHVEYYQEGEISEGC 362
Query: 120 LRIQDLDTTDTGYYQCVATNGMKTITAT 147
L + G Y +A N + T T
Sbjct: 363 LLFNKPTHYNNGNYTLIAKNPLGTANQT 390
>gi|59889562 neurotrophic tyrosine kinase, receptor, type 3 isoform
a precursor [Homo sapiens]
Length = 839
Score = 239 bits (609), Expect = 1e-62
Identities = 128/308 (41%), Positives = 176/308 (57%), Gaps = 16/308 (5%)
Query: 458 NQHK-QAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGP 516
N HK ++ I + ELGE FGKV+ + +P + VA+K LKD
Sbjct: 522 NCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAA 581
Query: 517 LREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGS 576
R++F+ EA L LQH ++V GV PL M+F Y HGDL++FL P + +
Sbjct: 582 -RKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILV 640
Query: 577 TDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGL 636
R K L +H+ +QIA+GM YL+S H VH+DLATRN LV L VKI D G+
Sbjct: 641 DGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGM 700
Query: 637 FREVYAADYYKLL--------------GNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVL 682
R+VY+ DYY+L G+++LPIRWM PE+IMY KF+ +SD+WS+GV+L
Sbjct: 701 SRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVIL 760
Query: 683 WEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDI 742
WE+F+YG QP+ SN +V+E I +VL P CP VY +M+ CW P +R K+I
Sbjct: 761 WEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 820
Query: 743 HSRLRAWG 750
+ L A G
Sbjct: 821 YKILHALG 828
Score = 35.8 bits (81), Expect = 0.19
Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Query: 70 NITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTD 129
N+T+ +G A++ C +G+P P+V W+ + + + + L + ++ + D
Sbjct: 218 NLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSED 277
Query: 130 TGY-YQCVATNGMKTITATGVLFVRLGP 156
G+ C+A N + A+ L V P
Sbjct: 278 NGFTLTCIAENVVGMSNASVALTVYYPP 305
Score = 31.6 bits (70), Expect = 3.6
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
Query: 67 PVNNITIVQGQTAILHC---KVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYG----SR 119
P +++ + + + HC V GNPPP + WL N P ++E + I + + G
Sbjct: 304 PPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQP-LRESKIIHVEYYQEGEISEGC 362
Query: 120 LRIQDLDTTDTGYYQCVATNGMKTITAT 147
L + G Y +A N + T T
Sbjct: 363 LLFNKPTHYNNGNYTLIAKNPLGTANQT 390
>gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isoform
1 [Homo sapiens]
Length = 790
Score = 238 bits (607), Expect = 2e-62
Identities = 119/271 (43%), Positives = 169/271 (62%), Gaps = 2/271 (0%)
Query: 478 ELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVV 537
ELGE FGKV+ P + VA+K LK+ +E R++F+ EA L LQH ++V
Sbjct: 509 ELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESA-RQDFQREAELLTMLQHQHIV 567
Query: 538 CLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVA 597
GV T+ +PL M+F Y HGDL+ FL P + + + +D L + + +
Sbjct: 568 RFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGED-VAPGPLGLGQLLAVAS 626
Query: 598 QIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIR 657
Q+AAGM YL+ H VH+DLATRN LV L VKI D G+ R++Y+ DYY++ G ++LPIR
Sbjct: 627 QVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIR 686
Query: 658 WMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDC 717
WM PE+I+Y KF+ +SD+WS+GVVLWE+F+YG QP+ SN + ++ I + L P C
Sbjct: 687 WMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRAC 746
Query: 718 PAWVYALMIECWNEFPSRRPRFKDIHSRLRA 748
P VYA+M CW P +R KD+H+RL+A
Sbjct: 747 PPEVYAIMRGCWQREPQQRHSIKDVHARLQA 777
>gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isoform 2
[Homo sapiens]
Length = 796
Score = 238 bits (607), Expect = 2e-62
Identities = 119/271 (43%), Positives = 169/271 (62%), Gaps = 2/271 (0%)
Query: 478 ELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVV 537
ELGE FGKV+ P + VA+K LK+ +E R++F+ EA L LQH ++V
Sbjct: 515 ELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESA-RQDFQREAELLTMLQHQHIV 573
Query: 538 CLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVA 597
GV T+ +PL M+F Y HGDL+ FL P + + + +D L + + +
Sbjct: 574 RFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGED-VAPGPLGLGQLLAVAS 632
Query: 598 QIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIR 657
Q+AAGM YL+ H VH+DLATRN LV L VKI D G+ R++Y+ DYY++ G ++LPIR
Sbjct: 633 QVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIR 692
Query: 658 WMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDC 717
WM PE+I+Y KF+ +SD+WS+GVVLWE+F+YG QP+ SN + ++ I + L P C
Sbjct: 693 WMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRAC 752
Query: 718 PAWVYALMIECWNEFPSRRPRFKDIHSRLRA 748
P VYA+M CW P +R KD+H+RL+A
Sbjct: 753 PPEVYAIMRGCWQREPQQRHSIKDVHARLQA 783
>gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isoform
3 [Homo sapiens]
Length = 760
Score = 238 bits (607), Expect = 2e-62
Identities = 119/271 (43%), Positives = 169/271 (62%), Gaps = 2/271 (0%)
Query: 478 ELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVV 537
ELGE FGKV+ P + VA+K LK+ +E R++F+ EA L LQH ++V
Sbjct: 479 ELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESA-RQDFQREAELLTMLQHQHIV 537
Query: 538 CLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVA 597
GV T+ +PL M+F Y HGDL+ FL P + + + +D L + + +
Sbjct: 538 RFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGED-VAPGPLGLGQLLAVAS 596
Query: 598 QIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIR 657
Q+AAGM YL+ H VH+DLATRN LV L VKI D G+ R++Y+ DYY++ G ++LPIR
Sbjct: 597 QVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIR 656
Query: 658 WMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDC 717
WM PE+I+Y KF+ +SD+WS+GVVLWE+F+YG QP+ SN + ++ I + L P C
Sbjct: 657 WMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRAC 716
Query: 718 PAWVYALMIECWNEFPSRRPRFKDIHSRLRA 748
P VYA+M CW P +R KD+H+RL+A
Sbjct: 717 PPEVYAIMRGCWQREPQQRHSIKDVHARLQA 747
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 206 bits (523), Expect = 1e-52
Identities = 122/287 (42%), Positives = 163/287 (56%), Gaps = 26/287 (9%)
Query: 466 KEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEA 525
KEI +S V+ E +G FG+VYKG L PG++ VAIKTLK R +F EA
Sbjct: 612 KEIDVSFVKIEEVIGAGEFGEVYKGRL--KLPGKREIYVAIKTLKAGYSEKQRRDFLSEA 669
Query: 526 MLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKS 585
+ + HPN++ L GVVTK +P+ +I + +G L FL D TV
Sbjct: 670 SIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFL---------RQNDGQFTVIQ 720
Query: 586 ALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAAD- 644
V ++ IAAGM+YL+ + VH+DLA RN+LV L K+SD GL R Y D
Sbjct: 721 ------LVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSR--YLQDD 772
Query: 645 -----YYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQ 699
Y LG + P+RW APEAI Y KF+ SD+WSYG+V+WEV S+G +PY SNQ
Sbjct: 773 TSDPTYTSSLGGKI-PVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQ 831
Query: 700 DVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRL 746
DV+ I LP P DCPA ++ LM++CW + + RPRF +I + L
Sbjct: 832 DVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTL 878
>gi|119395738 insulin receptor isoform Short precursor [Homo sapiens]
Length = 1370
Score = 205 bits (521), Expect = 2e-52
Identities = 110/281 (39%), Positives = 159/281 (56%), Gaps = 6/281 (2%)
Query: 467 EISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAM 526
E+S + + ELG+ FG VY+G+ GE VA+KT+ + A R EF +EA
Sbjct: 1005 EVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEAS 1064
Query: 527 LRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSA 586
+ +VV LLGVV+K QP ++ +HGDL +L P ++ T++
Sbjct: 1065 VMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQ-- 1122
Query: 587 LEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYY 646
+ + + A+IA GM YL++ VH+DLA RN +V VKI D G+ R++Y DYY
Sbjct: 1123 ----EMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYY 1178
Query: 647 KLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIR 706
+ G LLP+RWMAPE++ G F+ SD+WS+GVVLWE+ S QPY G SN+ V++ +
Sbjct: 1179 RKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVM 1238
Query: 707 NRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 747
+ L PD+CP V LM CW P RP F +I + L+
Sbjct: 1239 DGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLK 1279
>gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]
Length = 1382
Score = 205 bits (521), Expect = 2e-52
Identities = 110/281 (39%), Positives = 159/281 (56%), Gaps = 6/281 (2%)
Query: 467 EISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAM 526
E+S + + ELG+ FG VY+G+ GE VA+KT+ + A R EF +EA
Sbjct: 1017 EVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEAS 1076
Query: 527 LRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSA 586
+ +VV LLGVV+K QP ++ +HGDL +L P ++ T++
Sbjct: 1077 VMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQ-- 1134
Query: 587 LEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYY 646
+ + + A+IA GM YL++ VH+DLA RN +V VKI D G+ R++Y DYY
Sbjct: 1135 ----EMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYY 1190
Query: 647 KLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIR 706
+ G LLP+RWMAPE++ G F+ SD+WS+GVVLWE+ S QPY G SN+ V++ +
Sbjct: 1191 RKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVM 1250
Query: 707 NRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 747
+ L PD+CP V LM CW P RP F +I + L+
Sbjct: 1251 DGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLK 1291
>gi|62420886 discoidin domain receptor family, member 2 precursor
[Homo sapiens]
Length = 855
Score = 204 bits (520), Expect = 2e-52
Identities = 119/310 (38%), Positives = 172/310 (55%), Gaps = 25/310 (8%)
Query: 461 KQAKLKEISLSAVRFMEELGEDRFGKVYKGHLFG-----------PAPGEQTQAVAIKTL 509
K ++E + F E+LGE +FG+V+ + G Q VA+K L
Sbjct: 551 KDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKML 610
Query: 510 KDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRS 569
+ A R +F E + +RL+ PN++ LL V D PL MI Y +GDL++FL
Sbjct: 611 RADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHE 670
Query: 570 PHSDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNV 629
P + S+ D RTV + + QIA+GM+YLSS + VH+DLATRN LV +
Sbjct: 671 PPNS--SSSDVRTVSYT----NLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTI 724
Query: 630 KISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSY- 688
KI+D G+ R +Y+ DYY++ G ++LPIRWM+ E+I+ GKF+ SD+W++GV LWE F++
Sbjct: 725 KIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC 784
Query: 689 GLQPYCGYSNQDVVEMI------RNRQV-LPCPDDCPAWVYALMIECWNEFPSRRPRFKD 741
QPY S++ V+E + RQ LP P CP VY LM+ CW RP F++
Sbjct: 785 QEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQE 844
Query: 742 IHSRLRAWGN 751
IH L G+
Sbjct: 845 IHLLLLQQGD 854
>gi|62420884 discoidin domain receptor family, member 2 precursor
[Homo sapiens]
Length = 855
Score = 204 bits (520), Expect = 2e-52
Identities = 119/310 (38%), Positives = 172/310 (55%), Gaps = 25/310 (8%)
Query: 461 KQAKLKEISLSAVRFMEELGEDRFGKVYKGHLFG-----------PAPGEQTQAVAIKTL 509
K ++E + F E+LGE +FG+V+ + G Q VA+K L
Sbjct: 551 KDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKML 610
Query: 510 KDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRS 569
+ A R +F E + +RL+ PN++ LL V D PL MI Y +GDL++FL
Sbjct: 611 RADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHE 670
Query: 570 PHSDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNV 629
P + S+ D RTV + + QIA+GM+YLSS + VH+DLATRN LV +
Sbjct: 671 PPNS--SSSDVRTVSYT----NLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTI 724
Query: 630 KISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSY- 688
KI+D G+ R +Y+ DYY++ G ++LPIRWM+ E+I+ GKF+ SD+W++GV LWE F++
Sbjct: 725 KIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC 784
Query: 689 GLQPYCGYSNQDVVEMI------RNRQV-LPCPDDCPAWVYALMIECWNEFPSRRPRFKD 741
QPY S++ V+E + RQ LP P CP VY LM+ CW RP F++
Sbjct: 785 QEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQE 844
Query: 742 IHSRLRAWGN 751
IH L G+
Sbjct: 845 IHLLLLQQGD 854
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 204 bits (519), Expect = 3e-52
Identities = 127/344 (36%), Positives = 178/344 (51%), Gaps = 31/344 (9%)
Query: 416 LVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLI---------NQHKQAKLK 466
L+ + +VC R ++A + + Q S M + N+ + K
Sbjct: 555 LIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAK 614
Query: 467 EISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAM 526
EI +S V+ + +G FG+V GHL PG++ VAIKTLK R +F EA
Sbjct: 615 EIDISCVKIEQVIGAGEFGEVCSGHL--KLPGKREIFVAIKTLKSGYTEKQRRDFLSEAS 672
Query: 527 LRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSA 586
+ + HPNV+ L GVVTK P+ +I + +G L FL D TV
Sbjct: 673 IMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFL---------RQNDGQFTVIQ- 722
Query: 587 LEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFR----EVYA 642
V ++ IAAGM+YL+ + VH+DLA RN+LV L K+SD GL R +
Sbjct: 723 -----LVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSD 777
Query: 643 ADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVV 702
Y LG + PIRW APEAI Y KF+ SD+WSYG+V+WEV SYG +PY +NQDV+
Sbjct: 778 PTYTSALGGKI-PIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVI 836
Query: 703 EMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRL 746
I LP P DCP+ ++ LM++CW + + RP+F I + L
Sbjct: 837 NAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 203 bits (517), Expect = 5e-52
Identities = 138/392 (35%), Positives = 195/392 (49%), Gaps = 26/392 (6%)
Query: 391 VPSCSPRDSSKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQ 450
VPS D + +L + V + +VI F++ R+K + + + +
Sbjct: 535 VPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVR 594
Query: 451 DMEMPLI----NQHKQAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAI 506
P NQ + KEI S ++ + +G FG+V G L PG++ VAI
Sbjct: 595 TYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRL--KVPGKREICVAI 652
Query: 507 KTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLV 566
KTLK R +F EA + + HPN++ L GVVTK +P+ +I Y +G L FL
Sbjct: 653 KTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFL- 711
Query: 567 MRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDK 626
+D R L V ++ I +GM+YLS VH+DLA RN+LV
Sbjct: 712 ---------RKNDGRFTVIQL-----VGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSN 757
Query: 627 LNVKISDLGLFR--EVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWE 684
L K+SD G+ R E Y G + PIRW APEAI Y KF+ SD+WSYG+V+WE
Sbjct: 758 LVCKVSDFGMSRVLEDDPEAAYTTRGGKI-PIRWTAPEAIAYRKFTSASDVWSYGIVMWE 816
Query: 685 VFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHS 744
V SYG +PY SNQDV++ I LP P DCP ++ LM++CW + S RP+F I +
Sbjct: 817 VMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVN 876
Query: 745 RLRAWGNLSNYNSSAQTSGASNTTQTSSLSTS 776
L + N NS +T S+ T+ L S
Sbjct: 877 MLDKL--IRNPNSLKRTGTESSRPNTALLDPS 906
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 202 bits (515), Expect = 9e-52
Identities = 118/285 (41%), Positives = 159/285 (55%), Gaps = 22/285 (7%)
Query: 466 KEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEA 525
KEI +S V+ + +G FG+V GHL PG++ VAIKTLK R +F EA
Sbjct: 615 KEIDISCVKIEQVIGAGEFGEVCSGHL--KLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 672
Query: 526 MLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKS 585
+ + HPNV+ L GVVTK P+ +I + +G L FL D TV
Sbjct: 673 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFL---------RQNDGQFTVIQ 723
Query: 586 ALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFR----EVY 641
V ++ IAAGM+YL+ + VH+DLA RN+LV L K+SD GL R +
Sbjct: 724 ------LVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTS 777
Query: 642 AADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDV 701
Y LG + PIRW APEAI Y KF+ SD+WSYG+V+WEV SYG +PY +NQDV
Sbjct: 778 DPTYTSALGGKI-PIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDV 836
Query: 702 VEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRL 746
+ I LP P DCP+ ++ LM++CW + + RP+F I + L
Sbjct: 837 INAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 881
>gi|47524177 fibroblast growth factor receptor 4 isoform 2 precursor
[Homo sapiens]
Length = 762
Score = 201 bits (510), Expect = 3e-51
Identities = 107/267 (40%), Positives = 155/267 (58%), Gaps = 3/267 (1%)
Query: 479 LGEDRFGKVYKGHLFG--PAPGEQTQAVAIKTLKDKA-EGPLREEFRHEAMLRARLQHPN 535
LGE FG+V + FG PA +Q VA+K LKD A + L + +++ +H N
Sbjct: 433 LGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKN 492
Query: 536 VVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHL 595
++ LLGV T++ PL +I + G+L EFL R P S D R+ + L P V
Sbjct: 493 IINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSC 552
Query: 596 VAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLP 655
Q+A GM+YL S +H+DLA RNVLV + +KI+D GL R V+ DYYK N LP
Sbjct: 553 AYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLP 612
Query: 656 IRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPD 715
++WMAPEA+ ++ SD+WS+G++LWE+F+ G PY G +++ ++R + P
Sbjct: 613 VKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPP 672
Query: 716 DCPAWVYALMIECWNEFPSRRPRFKDI 742
CP +Y LM ECW+ PS+RP FK +
Sbjct: 673 HCPPELYGLMRECWHAAPSQRPTFKQL 699
Score = 43.9 bits (102), Expect = 7e-04
Identities = 27/85 (31%), Positives = 37/85 (43%)
Query: 76 GQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDTGYYQC 135
G T C AGNP P +RWLK+ E R IR L ++ + +D G Y C
Sbjct: 165 GNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTC 224
Query: 136 VATNGMKTITATGVLFVRLGPTHSP 160
+ N + +I +L V H P
Sbjct: 225 LVENAVGSIRYNYLLDVLERSPHRP 249
Score = 35.0 bits (79), Expect = 0.33
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 12/83 (14%)
Query: 70 NITIVQGQTAILHCKVAGNPPPNVRWLK-----------NDAPVVQEPRRIIIRKTEYGS 118
N T V G L CKV + P+++WLK + P VQ + I +E
Sbjct: 258 NTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEV-E 316
Query: 119 RLRIQDLDTTDTGYYQCVATNGM 141
L ++++ D G Y C+A N +
Sbjct: 317 VLYLRNVSAEDAGEYTCLAGNSI 339
>gi|47524175 fibroblast growth factor receptor 4 isoform 1 precursor
[Homo sapiens]
Length = 802
Score = 201 bits (510), Expect = 3e-51
Identities = 107/267 (40%), Positives = 155/267 (58%), Gaps = 3/267 (1%)
Query: 479 LGEDRFGKVYKGHLFG--PAPGEQTQAVAIKTLKDKA-EGPLREEFRHEAMLRARLQHPN 535
LGE FG+V + FG PA +Q VA+K LKD A + L + +++ +H N
Sbjct: 473 LGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKN 532
Query: 536 VVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHL 595
++ LLGV T++ PL +I + G+L EFL R P S D R+ + L P V
Sbjct: 533 IINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSC 592
Query: 596 VAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLP 655
Q+A GM+YL S +H+DLA RNVLV + +KI+D GL R V+ DYYK N LP
Sbjct: 593 AYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLP 652
Query: 656 IRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPD 715
++WMAPEA+ ++ SD+WS+G++LWE+F+ G PY G +++ ++R + P
Sbjct: 653 VKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPP 712
Query: 716 DCPAWVYALMIECWNEFPSRRPRFKDI 742
CP +Y LM ECW+ PS+RP FK +
Sbjct: 713 HCPPELYGLMRECWHAAPSQRPTFKQL 739
Score = 43.9 bits (102), Expect = 7e-04
Identities = 27/85 (31%), Positives = 37/85 (43%)
Query: 76 GQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDTGYYQC 135
G T C AGNP P +RWLK+ E R IR L ++ + +D G Y C
Sbjct: 165 GNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTC 224
Query: 136 VATNGMKTITATGVLFVRLGPTHSP 160
+ N + +I +L V H P
Sbjct: 225 LVENAVGSIRYNYLLDVLERSPHRP 249
Score = 35.0 bits (79), Expect = 0.33
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 12/83 (14%)
Query: 70 NITIVQGQTAILHCKVAGNPPPNVRWLK-----------NDAPVVQEPRRIIIRKTEYGS 118
N T V G L CKV + P+++WLK + P VQ + I +E
Sbjct: 258 NTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEV-E 316
Query: 119 RLRIQDLDTTDTGYYQCVATNGM 141
L ++++ D G Y C+A N +
Sbjct: 317 VLYLRNVSAEDAGEYTCLAGNSI 339
>gi|47524173 fibroblast growth factor receptor 4 isoform 1 precursor
[Homo sapiens]
Length = 802
Score = 201 bits (510), Expect = 3e-51
Identities = 107/267 (40%), Positives = 155/267 (58%), Gaps = 3/267 (1%)
Query: 479 LGEDRFGKVYKGHLFG--PAPGEQTQAVAIKTLKDKA-EGPLREEFRHEAMLRARLQHPN 535
LGE FG+V + FG PA +Q VA+K LKD A + L + +++ +H N
Sbjct: 473 LGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKN 532
Query: 536 VVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHL 595
++ LLGV T++ PL +I + G+L EFL R P S D R+ + L P V
Sbjct: 533 IINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSC 592
Query: 596 VAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLP 655
Q+A GM+YL S +H+DLA RNVLV + +KI+D GL R V+ DYYK N LP
Sbjct: 593 AYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLP 652
Query: 656 IRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPD 715
++WMAPEA+ ++ SD+WS+G++LWE+F+ G PY G +++ ++R + P
Sbjct: 653 VKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPP 712
Query: 716 DCPAWVYALMIECWNEFPSRRPRFKDI 742
CP +Y LM ECW+ PS+RP FK +
Sbjct: 713 HCPPELYGLMRECWHAAPSQRPTFKQL 739
Score = 43.9 bits (102), Expect = 7e-04
Identities = 27/85 (31%), Positives = 37/85 (43%)
Query: 76 GQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDTGYYQC 135
G T C AGNP P +RWLK+ E R IR L ++ + +D G Y C
Sbjct: 165 GNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTC 224
Query: 136 VATNGMKTITATGVLFVRLGPTHSP 160
+ N + +I +L V H P
Sbjct: 225 LVENAVGSIRYNYLLDVLERSPHRP 249
Score = 35.0 bits (79), Expect = 0.33
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 12/83 (14%)
Query: 70 NITIVQGQTAILHCKVAGNPPPNVRWLK-----------NDAPVVQEPRRIIIRKTEYGS 118
N T V G L CKV + P+++WLK + P VQ + I +E
Sbjct: 258 NTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEV-E 316
Query: 119 RLRIQDLDTTDTGYYQCVATNGM 141
L ++++ D G Y C+A N +
Sbjct: 317 VLYLRNVSAEDAGEYTCLAGNSI 339
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 199 bits (506), Expect = 1e-50
Identities = 118/285 (41%), Positives = 160/285 (56%), Gaps = 22/285 (7%)
Query: 466 KEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEA 525
KEI +S V+ E +G FG+V +G L APG++ VAIKTLK R EF EA
Sbjct: 608 KEIDVSYVKIEEVIGAGEFGEVCRGRL--KAPGKKESCVAIKTLKGGYTERQRREFLSEA 665
Query: 526 MLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKS 585
+ + +HPN++ L GVVT P+ ++ + +G L FL + D TV
Sbjct: 666 SIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLN---------DGQFTVIQ 716
Query: 586 ALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGL--FREVYAA 643
V ++ IA+GM YL+ VH+DLA RN+LV L K+SD GL F E ++
Sbjct: 717 ------LVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSS 770
Query: 644 D--YYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDV 701
D Y LG + PIRW APEAI + KF+ SD WSYG+V+WEV S+G +PY SNQDV
Sbjct: 771 DPTYTSSLGGKI-PIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDV 829
Query: 702 VEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRL 746
+ I LP P DCP ++ LM++CW + + RPRF + S L
Sbjct: 830 INAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSAL 874
>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
sapiens]
Length = 1367
Score = 198 bits (504), Expect = 2e-50
Identities = 107/284 (37%), Positives = 155/284 (54%), Gaps = 12/284 (4%)
Query: 467 EISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAM 526
E++ + ELG+ FG VY+G G E VAIKT+ + A R EF +EA
Sbjct: 993 EVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEAS 1052
Query: 527 LRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSA 586
+ +VV LLGVV++ QP +I + GDL +L P +
Sbjct: 1053 VMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPV--------- 1103
Query: 587 LEPPDF---VHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAA 643
L PP + + +IA GM YL+++ VH+DLA RN +V + VKI D G+ R++Y
Sbjct: 1104 LAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYET 1163
Query: 644 DYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVE 703
DYY+ G LLP+RWM+PE++ G F+ SD+WS+GVVLWE+ + QPY G SN+ V+
Sbjct: 1164 DYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLR 1223
Query: 704 MIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 747
+ +L PD+CP ++ LM CW P RP F +I S ++
Sbjct: 1224 FVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK 1267
>gi|38327632 discoidin domain receptor family, member 1 isoform b
[Homo sapiens]
Length = 876
Score = 198 bits (503), Expect = 2e-50
Identities = 112/295 (37%), Positives = 166/295 (56%), Gaps = 22/295 (7%)
Query: 471 SAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQ-----------AVAIKTLKDKAEGPLRE 519
S +RF E+LGE +FG+V+ + P VA+K L+ A R
Sbjct: 571 SRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARN 630
Query: 520 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDV--GST 577
+F E + +RL+ PN++ LLGV +D PL MI Y +GDL++FL G+
Sbjct: 631 DFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAP 690
Query: 578 DDDRTVKS-ALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGL 636
D + + + P +H+ AQIA+GM YL++ + VH+DLATRN LV + +KI+D G+
Sbjct: 691 GDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGM 750
Query: 637 FREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSY-GLQPYCG 695
R +YA DYY++ G ++LPIRWMA E I+ GKF+ SD+W++GV LWEV QP+
Sbjct: 751 SRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQ 810
Query: 696 YSNQDVVEMI------RNRQV-LPCPDDCPAWVYALMIECWNEFPSRRPRFKDIH 743
+++ V+E + RQV L P CP +Y LM+ CW+ +RP F +H
Sbjct: 811 LTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLH 865
>gi|83977450 discoidin domain receptor family, member 1 isoform a
[Homo sapiens]
Length = 913
Score = 198 bits (503), Expect = 2e-50
Identities = 112/295 (37%), Positives = 166/295 (56%), Gaps = 22/295 (7%)
Query: 471 SAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQ-----------AVAIKTLKDKAEGPLRE 519
S +RF E+LGE +FG+V+ + P VA+K L+ A R
Sbjct: 608 SRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARN 667
Query: 520 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDV--GST 577
+F E + +RL+ PN++ LLGV +D PL MI Y +GDL++FL G+
Sbjct: 668 DFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAP 727
Query: 578 DDDRTVKS-ALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGL 636
D + + + P +H+ AQIA+GM YL++ + VH+DLATRN LV + +KI+D G+
Sbjct: 728 GDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGM 787
Query: 637 FREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSY-GLQPYCG 695
R +YA DYY++ G ++LPIRWMA E I+ GKF+ SD+W++GV LWEV QP+
Sbjct: 788 SRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQ 847
Query: 696 YSNQDVVEMI------RNRQV-LPCPDDCPAWVYALMIECWNEFPSRRPRFKDIH 743
+++ V+E + RQV L P CP +Y LM+ CW+ +RP F +H
Sbjct: 848 LTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLH 902
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 197 bits (502), Expect = 3e-50
Identities = 119/359 (33%), Positives = 177/359 (49%), Gaps = 31/359 (8%)
Query: 467 EISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAM 526
EI + +GE +FG V++G P AVAIKT K+ +RE+F EA+
Sbjct: 438 EIQRERIELGRCIGEGQFGDVHQGIYMSPE--NPALAVAIKTCKNCTSDSVREKFLQEAL 495
Query: 527 LRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSA 586
+ HP++V L+GV+T++ P+ +I C+ G+L FL +R K +
Sbjct: 496 TMRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVR---------------KYS 539
Query: 587 LEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYY 646
L+ + Q++ + YL S VH+D+A RNVLV VK+ D GL R + + YY
Sbjct: 540 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 599
Query: 647 KLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIR 706
K LPI+WMAPE+I + +F+ SD+W +GV +WE+ +G++P+ G N DV+ I
Sbjct: 600 KA-SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE 658
Query: 707 NRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASN 766
N + LP P +CP +Y+LM +CW PSRRPRF ++ ++L + S
Sbjct: 659 NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESR 718
Query: 767 TTQTSSLSTSPVSNVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQ 825
T S + G +APP P P P PQ V N YQ
Sbjct: 719 RQATVSWDS------------GGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQ 765
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 197 bits (502), Expect = 3e-50
Identities = 119/359 (33%), Positives = 177/359 (49%), Gaps = 31/359 (8%)
Query: 467 EISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAM 526
EI + +GE +FG V++G P AVAIKT K+ +RE+F EA+
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPE--NPALAVAIKTCKNCTSDSVREKFLQEAL 473
Query: 527 LRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSA 586
+ HP++V L+GV+T++ P+ +I C+ G+L FL +R K +
Sbjct: 474 TMRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVR---------------KYS 517
Query: 587 LEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYY 646
L+ + Q++ + YL S VH+D+A RNVLV VK+ D GL R + + YY
Sbjct: 518 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 577
Query: 647 KLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIR 706
K LPI+WMAPE+I + +F+ SD+W +GV +WE+ +G++P+ G N DV+ I
Sbjct: 578 KA-SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE 636
Query: 707 NRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASN 766
N + LP P +CP +Y+LM +CW PSRRPRF ++ ++L + S
Sbjct: 637 NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESR 696
Query: 767 TTQTSSLSTSPVSNVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQ 825
T S + G +APP P P P PQ V N YQ
Sbjct: 697 RQATVSWDS------------GGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQ 743
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 197 bits (501), Expect = 4e-50
Identities = 131/362 (36%), Positives = 190/362 (52%), Gaps = 28/362 (7%)
Query: 395 SPRDSSKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEM 454
SP S + ++ + + + LV+A + F + R Q+A S P+ S
Sbjct: 528 SPEGSGNLAVIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQS-PEDVYFSKSEQLKPLK 586
Query: 455 PLINQH-----KQAKLK---EISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAI 506
++ H QA LK EI S V + +G FG+VYKG L + G++ VAI
Sbjct: 587 TYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGML-KTSSGKKEVPVAI 645
Query: 507 KTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLV 566
KTLK R +F EA + + H N++ L GV++K +P+ +I Y +G L +FL
Sbjct: 646 KTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFL- 704
Query: 567 MRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDK 626
R V ++ IAAGM+YL++ + VH+DLA RN+LV
Sbjct: 705 --------------REKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSN 750
Query: 627 LNVKISDLGLFR--EVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWE 684
L K+SD GL R E Y G + PIRW APEAI Y KF+ SD+WS+G+V+WE
Sbjct: 751 LVCKVSDFGLSRVLEDDPEATYTTSGGKI-PIRWTAPEAISYRKFTSASDVWSFGIVMWE 809
Query: 685 VFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHS 744
V +YG +PY SN +V++ I + LP P DCP+ +Y LM++CW + +RRP+F DI S
Sbjct: 810 VMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVS 869
Query: 745 RL 746
L
Sbjct: 870 IL 871
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 197 bits (500), Expect = 5e-50
Identities = 114/279 (40%), Positives = 155/279 (55%), Gaps = 20/279 (7%)
Query: 466 KEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEA 525
KE+ S ++ +G FG+V G L PG++ AVAIKTLK R +F EA
Sbjct: 626 KELDASCIKIERVIGAGEFGEVCSGRL--KLPGKRDVAVAIKTLKVGYTEKQRRDFLCEA 683
Query: 526 MLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKS 585
+ + HPNVV L GVVT+ +P+ ++ + +G L FL D TV
Sbjct: 684 SIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKH---------DGQFTVIQ 734
Query: 586 ALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVY--AA 643
V ++ IAAGM YL+ VH+DLA RN+LV L K+SD GL R +
Sbjct: 735 ------LVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPE 788
Query: 644 DYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVE 703
Y G + P+RW APEAI Y KF+ SD+WSYG+V+WEV SYG +PY SNQDV++
Sbjct: 789 AVYTTTGGKI-PVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIK 847
Query: 704 MIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDI 742
I LP P DCPA ++ LM++CW + + RP+F+ I
Sbjct: 848 AIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQI 886
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,774,417
Number of Sequences: 37866
Number of extensions: 2106652
Number of successful extensions: 12140
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 694
Number of HSP's successfully gapped in prelim test: 533
Number of HSP's that attempted gapping in prelim test: 7685
Number of HSP's gapped (non-prelim): 3166
length of query: 943
length of database: 18,247,518
effective HSP length: 112
effective length of query: 831
effective length of database: 14,006,526
effective search space: 11639423106
effective search space used: 11639423106
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.