Guide to the Human Genome
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Search of human proteins with 19743854

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19743854 decorin isoform e precursor [Homo sapiens]
         (75 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19743854 decorin isoform e precursor [Homo sapiens]                161   9e-41
gi|19743850 decorin isoform c precursor [Homo sapiens]                155   9e-39
gi|19743846 decorin isoform a preproprotein [Homo sapiens]            152   6e-38
gi|4503271 decorin isoform a preproprotein [Homo sapiens]             152   6e-38
gi|19743852 decorin isoform d precursor [Homo sapiens]                152   6e-38
gi|19743848 decorin isoform b precursor [Homo sapiens]                150   3e-37
gi|4502403 biglycan preproprotein [Homo sapiens]                       64   3e-11
gi|41350214 asporin [Homo sapiens]                                     44   3e-05
gi|38454322 adhesion molecule with Ig-like domain 3 [Homo sapiens]     31   0.19 
gi|188528675 slit homolog 1 [Homo sapiens]                             30   0.42 
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s...    29   0.94 
gi|11321571 slit homolog 3 [Homo sapiens]                              28   2.1  
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho...    28   2.1  
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]       27   3.6  
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]       27   3.6  
gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sa...    27   4.6  
gi|30089980 chordin [Homo sapiens]                                     26   6.1  
gi|4759146 slit homolog 2 [Homo sapiens]                               26   6.1  
gi|110611908 mitogen-activated protein kinase kinase kinase kina...    26   6.1  
gi|6005810 mitogen-activated protein kinase kinase kinase kinase...    26   6.1  
gi|6912246 CD3E antigen, epsilon polypeptide associated protein ...    26   6.1  
gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso...    26   6.1  
gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 iso...    26   6.1  
gi|45545424 LISCH protein isoform 2 [Homo sapiens]                     26   7.9  
gi|45505163 LISCH protein isoform 1 [Homo sapiens]                     26   7.9  
gi|40786420 immunoglobulin-like domain containing receptor 2 [Ho...    26   7.9  
gi|52353306 leucine rich repeat containing 55 [Homo sapiens]           26   7.9  

>gi|19743854 decorin isoform e precursor [Homo sapiens]
          Length = 75

 Score =  161 bits (408), Expect = 9e-41
 Identities = 75/75 (100%), Positives = 75/75 (100%)

Query: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
          MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60

Query: 61 HLRVVQCSDLGCLPS 75
          HLRVVQCSDLGCLPS
Sbjct: 61 HLRVVQCSDLGCLPS 75


>gi|19743850 decorin isoform c precursor [Homo sapiens]
          Length = 212

 Score =  155 bits (391), Expect = 9e-39
 Identities = 73/75 (97%), Positives = 73/75 (97%)

Query: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
          MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60

Query: 61 HLRVVQCSDLGCLPS 75
          HLRVVQCSDLG  PS
Sbjct: 61 HLRVVQCSDLGLPPS 75


>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score =  152 bits (384), Expect = 6e-38
 Identities = 71/71 (100%), Positives = 71/71 (100%)

Query: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
          MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60

Query: 61 HLRVVQCSDLG 71
          HLRVVQCSDLG
Sbjct: 61 HLRVVQCSDLG 71


>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score =  152 bits (384), Expect = 6e-38
 Identities = 71/71 (100%), Positives = 71/71 (100%)

Query: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
          MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60

Query: 61 HLRVVQCSDLG 71
          HLRVVQCSDLG
Sbjct: 61 HLRVVQCSDLG 71


>gi|19743852 decorin isoform d precursor [Homo sapiens]
          Length = 172

 Score =  152 bits (384), Expect = 6e-38
 Identities = 71/71 (100%), Positives = 71/71 (100%)

Query: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
          MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60

Query: 61 HLRVVQCSDLG 71
          HLRVVQCSDLG
Sbjct: 61 HLRVVQCSDLG 71


>gi|19743848 decorin isoform b precursor [Homo sapiens]
          Length = 250

 Score =  150 bits (378), Expect = 3e-37
 Identities = 70/70 (100%), Positives = 70/70 (100%)

Query: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
          MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1  MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60

Query: 61 HLRVVQCSDL 70
          HLRVVQCSDL
Sbjct: 61 HLRVVQCSDL 70


>gi|4502403 biglycan preproprotein [Homo sapiens]
          Length = 368

 Score = 63.9 bits (154), Expect = 3e-11
 Identities = 36/74 (48%), Positives = 43/74 (58%), Gaps = 9/74 (12%)

Query: 7  LLLLAQVSWAGPFQQRGLFDFMLED--------EASGIGPE-VPDDRDFEPSLGPVCPFR 57
          L+ L  +S A PF+QRG +DF L+D        EASG     V D     P+   +CPF 
Sbjct: 7  LVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFG 66

Query: 58 CQCHLRVVQCSDLG 71
          C CHLRVVQCSDLG
Sbjct: 67 CHCHLRVVQCSDLG 80


>gi|41350214 asporin [Homo sapiens]
          Length = 380

 Score = 43.9 bits (102), Expect = 3e-05
 Identities = 34/93 (36%), Positives = 41/93 (44%), Gaps = 23/93 (24%)

Query: 1  MKATIILLLLAQVSWAGPF---QQRGLFDFMLEDEASGIGPEVPDDRD------------ 45
          MK  ++LL LA  S A PF       L + ML+D       +  DD D            
Sbjct: 1  MKEYVLLLFLALCS-AKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPT 59

Query: 46 -------FEPSLGPVCPFRCQCHLRVVQCSDLG 71
                 F   L P+CPF CQC+ RVV CSDLG
Sbjct: 60 REPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLG 92


>gi|38454322 adhesion molecule with Ig-like domain 3 [Homo
          sapiens]
          Length = 504

 Score = 31.2 bits (69), Expect = 0.19
 Identities = 12/36 (33%), Positives = 18/36 (50%)

Query: 36 IGPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCSDLG 71
          +G   PD   F P     CP++C C   ++ C+ LG
Sbjct: 16 VGLGTPDSEGFPPRALHNCPYKCICAADLLSCTGLG 51


>gi|188528675 slit homolog 1 [Homo sapiens]
          Length = 1534

 Score = 30.0 bits (66), Expect = 0.42
 Identities = 10/18 (55%), Positives = 13/18 (72%)

Query: 53  VCPFRCQCHLRVVQCSDL 70
           VCP +C+C   VV+CS L
Sbjct: 512 VCPHKCRCEANVVECSSL 529


>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
           sapiens]
          Length = 1037

 Score = 28.9 bits (63), Expect = 0.94
 Identities = 9/11 (81%), Positives = 9/11 (81%)

Query: 51  GPVCPFRCQCH 61
           GP C FRCQCH
Sbjct: 184 GPACQFRCQCH 194


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 11/22 (50%), Positives = 14/22 (63%)

Query: 50  LGPVCPFRCQCHLRVVQCSDLG 71
           L P CP +C C   VV+CS+ G
Sbjct: 721 LSPRCPEQCTCMETVVRCSNKG 742


>gi|84781739 leucine-rich repeats and transmembrane domains 2
          [Homo sapiens]
          Length = 370

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 12/22 (54%), Positives = 13/22 (59%), Gaps = 2/22 (9%)

Query: 52 PVCPFRCQCHLR--VVQCSDLG 71
          P CPF C+C  R   V CS LG
Sbjct: 37 PTCPFSCKCDSRSLEVDCSGLG 58


>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
          Length = 660

 Score = 26.9 bits (58), Expect = 3.6
 Identities = 14/42 (33%), Positives = 17/42 (40%), Gaps = 1/42 (2%)

Query: 32 EASGIGPEVPD-DRDFEPSLGPVCPFRCQCHLRVVQCSDLGC 72
          E  G  PE PD   D +   G   P  C C    + C  +GC
Sbjct: 2  EGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGC 43


>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
          Length = 656

 Score = 26.9 bits (58), Expect = 3.6
 Identities = 14/42 (33%), Positives = 17/42 (40%), Gaps = 1/42 (2%)

Query: 32 EASGIGPEVPD-DRDFEPSLGPVCPFRCQCHLRVVQCSDLGC 72
          E  G  PE PD   D +   G   P  C C    + C  +GC
Sbjct: 2  EGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGC 43


>gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo
          sapiens]
          Length = 516

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 9/24 (37%), Positives = 13/24 (54%)

Query: 48 PSLGPVCPFRCQCHLRVVQCSDLG 71
          P+LG  CP +C+C   +  C   G
Sbjct: 28 PALGMACPPKCRCEKLLFYCDSQG 51


>gi|30089980 chordin [Homo sapiens]
          Length = 955

 Score = 26.2 bits (56), Expect = 6.1
 Identities = 12/38 (31%), Positives = 17/38 (44%), Gaps = 1/38 (2%)

Query: 37  GPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCSDLGCLP 74
           G + P    + P+  P+C   C C  R V C  + C P
Sbjct: 709 GQQRPHGARWAPNYDPLCSL-CTCQRRTVICDPVVCPP 745


>gi|4759146 slit homolog 2 [Homo sapiens]
          Length = 1529

 Score = 26.2 bits (56), Expect = 6.1
 Identities = 13/32 (40%), Positives = 18/32 (56%), Gaps = 2/32 (6%)

Query: 42  DDRDFEPSLGPV--CPFRCQCHLRVVQCSDLG 71
           DD + + S  P+  CP  C C   VV+CS+ G
Sbjct: 713 DDGNDDNSCSPLSRCPTECTCLDTVVRCSNKG 744


>gi|110611908 mitogen-activated protein kinase kinase kinase kinase
           1 isoform 1 [Homo sapiens]
          Length = 821

 Score = 26.2 bits (56), Expect = 6.1
 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 1/41 (2%)

Query: 18  PFQQRGLF-DFMLEDEASGIGPEVPDDRDFEPSLGPVCPFR 57
           P   RGL  D + + +  G GP + D  D EP L P  P R
Sbjct: 277 PGLNRGLILDLLDKLKNPGKGPSIGDIEDEEPELPPAIPRR 317


>gi|6005810 mitogen-activated protein kinase kinase kinase kinase 1
           isoform 2 [Homo sapiens]
          Length = 833

 Score = 26.2 bits (56), Expect = 6.1
 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 1/41 (2%)

Query: 18  PFQQRGLF-DFMLEDEASGIGPEVPDDRDFEPSLGPVCPFR 57
           P   RGL  D + + +  G GP + D  D EP L P  P R
Sbjct: 277 PGLNRGLILDLLDKLKNPGKGPSIGDIEDEEPELPPAIPRR 317


>gi|6912246 CD3E antigen, epsilon polypeptide associated protein
           [Homo sapiens]
          Length = 510

 Score = 26.2 bits (56), Expect = 6.1
 Identities = 12/27 (44%), Positives = 15/27 (55%), Gaps = 2/27 (7%)

Query: 26  DFMLEDEASGIGPEVPDDRDFEPSLGP 52
           D  +E E   +GPE+PD  D EP   P
Sbjct: 394 DATVEPETEVVGPELPD--DLEPQAAP 418


>gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1
           isoform d [Homo sapiens]
          Length = 756

 Score = 26.2 bits (56), Expect = 6.1
 Identities = 13/50 (26%), Positives = 24/50 (48%), Gaps = 3/50 (6%)

Query: 20  QQRGLFDFMLEDEASGIGPEVP---DDRDFEPSLGPVCPFRCQCHLRVVQ 66
           + RG   F   ++  G  P+ P   D+ DF+ +L  +  + C  H +V +
Sbjct: 77  ENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVAR 126


>gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1
           isoform a [Homo sapiens]
          Length = 856

 Score = 26.2 bits (56), Expect = 6.1
 Identities = 13/50 (26%), Positives = 24/50 (48%), Gaps = 3/50 (6%)

Query: 20  QQRGLFDFMLEDEASGIGPEVP---DDRDFEPSLGPVCPFRCQCHLRVVQ 66
           + RG   F   ++  G  P+ P   D+ DF+ +L  +  + C  H +V +
Sbjct: 177 ENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVAR 226


>gi|45545424 LISCH protein isoform 2 [Homo sapiens]
          Length = 649

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 9/21 (42%), Positives = 11/21 (52%)

Query: 54  CPFRCQCHLRVVQCSDLGCLP 74
           CP  C C++R   C D  C P
Sbjct: 285 CPHTCCCYVRCPCCPDKCCCP 305


>gi|45505163 LISCH protein isoform 1 [Homo sapiens]
          Length = 630

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 9/21 (42%), Positives = 11/21 (52%)

Query: 54  CPFRCQCHLRVVQCSDLGCLP 74
           CP  C C++R   C D  C P
Sbjct: 266 CPHTCCCYVRCPCCPDKCCCP 286


>gi|40786420 immunoglobulin-like domain containing receptor 2 [Homo
           sapiens]
          Length = 639

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 9/21 (42%), Positives = 11/21 (52%)

Query: 54  CPFRCQCHLRVVQCSDLGCLP 74
           CP  C C++R   C D  C P
Sbjct: 212 CPHSCCCYVRCPCCPDSCCCP 232


>gi|52353306 leucine rich repeat containing 55 [Homo sapiens]
          Length = 341

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 18/58 (31%), Positives = 23/58 (39%), Gaps = 11/58 (18%)

Query: 11 AQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCS 68
          AQ+ W GP     L   +L   A+G+              G  CP  C C  +VV CS
Sbjct: 49 AQLPWPGPPHPAMLLISLLL--AAGL---------MHSDAGTSCPVLCTCRNQVVDCS 95


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.145    0.482 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,291,133
Number of Sequences: 37866
Number of extensions: 130958
Number of successful extensions: 458
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 428
Number of HSP's gapped (non-prelim): 40
length of query: 75
length of database: 18,247,518
effective HSP length: 47
effective length of query: 28
effective length of database: 16,467,816
effective search space: 461098848
effective search space used: 461098848
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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