BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|197333809 joined to JAZF1 [Homo sapiens] (739 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|197333809 joined to JAZF1 [Homo sapiens] 1501 0.0 gi|239756770 PREDICTED: similar to KIAA0160 [Homo sapiens] 220 4e-57 gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 58 4e-08 gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 58 4e-08 gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 58 4e-08 gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 57 5e-08 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 57 5e-08 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 57 5e-08 gi|195972866 keratin 10 [Homo sapiens] 56 1e-07 gi|109255251 loricrin [Homo sapiens] 53 9e-07 gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 53 1e-06 gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 52 2e-06 gi|55956899 keratin 9 [Homo sapiens] 52 2e-06 gi|194018511 keratin 77 [Homo sapiens] 51 3e-06 gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 51 3e-06 gi|47132620 keratin 2 [Homo sapiens] 51 3e-06 gi|45439359 triple functional domain (PTPRF interacting) [Homo s... 51 4e-06 gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens] 50 6e-06 gi|4502565 calpain, small subunit 1 [Homo sapiens] 50 8e-06 gi|51599151 calpain, small subunit 1 [Homo sapiens] 50 8e-06 gi|119395750 keratin 1 [Homo sapiens] 50 1e-05 gi|109452587 family with sequence similarity 98, member B isofor... 50 1e-05 gi|12707580 paired-like homeobox 2b [Homo sapiens] 49 1e-05 gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 49 2e-05 gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens] 49 2e-05 gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 48 3e-05 gi|13775236 scratch [Homo sapiens] 48 3e-05 gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi... 48 4e-05 gi|34452713 Ca2+-dependent secretion activator isoform 2 [Homo s... 48 4e-05 gi|34452715 Ca2+-dependent secretion activator isoform 1 [Homo s... 48 4e-05 >gi|197333809 joined to JAZF1 [Homo sapiens] Length = 739 Score = 1501 bits (3887), Expect = 0.0 Identities = 739/739 (100%), Positives = 739/739 (100%) Query: 1 MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA 60 MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA Sbjct: 1 MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA 60 Query: 61 AAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSH 120 AAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSH Sbjct: 61 AAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSH 120 Query: 121 RNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQN 180 RNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQN Sbjct: 121 RNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQN 180 Query: 181 SVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPS 240 SVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPS Sbjct: 181 SVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPS 240 Query: 241 NSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMT 300 NSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMT Sbjct: 241 NSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMT 300 Query: 301 VFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLR 360 VFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLR Sbjct: 301 VFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLR 360 Query: 361 WTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPN 420 WTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPN Sbjct: 361 WTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPN 420 Query: 421 ENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVY 480 ENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVY Sbjct: 421 ENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVY 480 Query: 481 HPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASM 540 HPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASM Sbjct: 481 HPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASM 540 Query: 541 SEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQI 600 SEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQI Sbjct: 541 SEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQI 600 Query: 601 EEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHL 660 EEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHL Sbjct: 601 EEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHL 660 Query: 661 VSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEK 720 VSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEK Sbjct: 661 VSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEK 720 Query: 721 ALETDSVSGVSKQSKKQKL 739 ALETDSVSGVSKQSKKQKL Sbjct: 721 ALETDSVSGVSKQSKKQKL 739 >gi|239756770 PREDICTED: similar to KIAA0160 [Homo sapiens] Length = 172 Score = 220 bits (560), Expect = 4e-57 Identities = 106/108 (98%), Positives = 106/108 (98%) Query: 163 GFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQT 222 GFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDV CPIRQVPTGKKQVPLNPDLNQT Sbjct: 37 GFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVCCPIRQVPTGKKQVPLNPDLNQT 96 Query: 223 KPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGET 270 KPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRP RREFNGMINGET Sbjct: 97 KPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPRRREFNGMINGET 144 >gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] Length = 558 Score = 57.8 bits (138), Expect = 4e-08 Identities = 34/79 (43%), Positives = 45/79 (56%), Gaps = 18/79 (22%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAA-------VAAATASGGKSGGGSCGGG---------- 49 GGGG GG G S+G+GGGG GG AA+ SGG GG S GGG Sbjct: 78 GGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINAS 137 Query: 50 -GSYSASSSSSAAAAAGAA 67 GS S+SSSSS+++++ ++ Sbjct: 138 TGSSSSSSSSSSSSSSSSS 156 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/75 (40%), Positives = 39/75 (52%), Gaps = 15/75 (20%) Query: 6 HGGGGGGGSGPS------------AGSGGGGFGGSAAVAAAT---ASGGKSGGGSCGGGG 50 +GGGGGGG G S +G GGGG VA++T AS G S S Sbjct: 91 NGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSS 150 Query: 51 SYSASSSSSAAAAAG 65 S S+SSSSS++++ G Sbjct: 151 SSSSSSSSSSSSSCG 165 Score = 38.9 bits (89), Expect = 0.017 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 6/62 (9%) Query: 15 GPSAGSGGGGF------GGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAV 68 GP A SG F +AA A T++GG GGG GGGG S + G+ Sbjct: 45 GPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNC 104 Query: 69 LP 70 P Sbjct: 105 NP 106 Score = 38.5 bits (88), Expect = 0.023 Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 4/60 (6%) Query: 1 MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA 60 +A +G GGGGG S GGG S + A+T S S S S S+SSSSS+ Sbjct: 108 LAAASNGSGGGGGG---I-SAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSS 163 Score = 36.6 bits (83), Expect = 0.086 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 6/65 (9%) Query: 3 PQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAA 62 P+ + ++ GGGG GGS GG SG G GGGG ++ + + AA Sbjct: 57 PEPIASAAAAAATVTSTGGGGGGGGSG------GGGGSSGNGGGGGGGGGGSNCNPNLAA 110 Query: 63 AAGAA 67 A+ + Sbjct: 111 ASNGS 115 Score = 33.9 bits (76), Expect = 0.56 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 5/49 (10%) Query: 17 SAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 + G GGGG G S G GGG GGGGS + ++A+ +G Sbjct: 73 TGGGGGGGGSGGGG-----GSSGNGGGGGGGGGGSNCNPNLAAASNGSG 116 >gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] Length = 706 Score = 57.8 bits (138), Expect = 4e-08 Identities = 34/79 (43%), Positives = 45/79 (56%), Gaps = 18/79 (22%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAA-------VAAATASGGKSGGGSCGGG---------- 49 GGGG GG G S+G+GGGG GG AA+ SGG GG S GGG Sbjct: 78 GGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINAS 137 Query: 50 -GSYSASSSSSAAAAAGAA 67 GS S+SSSSS+++++ ++ Sbjct: 138 TGSSSSSSSSSSSSSSSSS 156 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/75 (40%), Positives = 39/75 (52%), Gaps = 15/75 (20%) Query: 6 HGGGGGGGSGPS------------AGSGGGGFGGSAAVAAAT---ASGGKSGGGSCGGGG 50 +GGGGGGG G S +G GGGG VA++T AS G S S Sbjct: 91 NGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSS 150 Query: 51 SYSASSSSSAAAAAG 65 S S+SSSSS++++ G Sbjct: 151 SSSSSSSSSSSSSCG 165 Score = 38.9 bits (89), Expect = 0.017 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 6/62 (9%) Query: 15 GPSAGSGGGGF------GGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAV 68 GP A SG F +AA A T++GG GGG GGGG S + G+ Sbjct: 45 GPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNC 104 Query: 69 LP 70 P Sbjct: 105 NP 106 Score = 38.5 bits (88), Expect = 0.023 Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 4/60 (6%) Query: 1 MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA 60 +A +G GGGGG S GGG S + A+T S S S S S+SSSSS+ Sbjct: 108 LAAASNGSGGGGGG---I-SAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSS 163 Score = 36.6 bits (83), Expect = 0.086 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 6/65 (9%) Query: 3 PQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAA 62 P+ + ++ GGGG GGS GG SG G GGGG ++ + + AA Sbjct: 57 PEPIASAAAAAATVTSTGGGGGGGGSG------GGGGSSGNGGGGGGGGGGSNCNPNLAA 110 Query: 63 AAGAA 67 A+ + Sbjct: 111 ASNGS 115 Score = 33.9 bits (76), Expect = 0.56 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 5/49 (10%) Query: 17 SAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 + G GGGG G S G GGG GGGGS + ++A+ +G Sbjct: 73 TGGGGGGGGSGGGG-----GSSGNGGGGGGGGGGSNCNPNLAAASNGSG 116 >gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] Length = 504 Score = 57.8 bits (138), Expect = 4e-08 Identities = 34/79 (43%), Positives = 45/79 (56%), Gaps = 18/79 (22%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAA-------VAAATASGGKSGGGSCGGG---------- 49 GGGG GG G S+G+GGGG GG AA+ SGG GG S GGG Sbjct: 78 GGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINAS 137 Query: 50 -GSYSASSSSSAAAAAGAA 67 GS S+SSSSS+++++ ++ Sbjct: 138 TGSSSSSSSSSSSSSSSSS 156 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/75 (40%), Positives = 39/75 (52%), Gaps = 15/75 (20%) Query: 6 HGGGGGGGSGPS------------AGSGGGGFGGSAAVAAAT---ASGGKSGGGSCGGGG 50 +GGGGGGG G S +G GGGG VA++T AS G S S Sbjct: 91 NGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSS 150 Query: 51 SYSASSSSSAAAAAG 65 S S+SSSSS++++ G Sbjct: 151 SSSSSSSSSSSSSCG 165 Score = 38.9 bits (89), Expect = 0.017 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 6/62 (9%) Query: 15 GPSAGSGGGGF------GGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAV 68 GP A SG F +AA A T++GG GGG GGGG S + G+ Sbjct: 45 GPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNC 104 Query: 69 LP 70 P Sbjct: 105 NP 106 Score = 38.5 bits (88), Expect = 0.023 Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 4/60 (6%) Query: 1 MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA 60 +A +G GGGGG S GGG S + A+T S S S S S+SSSSS+ Sbjct: 108 LAAASNGSGGGGGG---I-SAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSS 163 Score = 36.6 bits (83), Expect = 0.086 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 6/65 (9%) Query: 3 PQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAA 62 P+ + ++ GGGG GGS GG SG G GGGG ++ + + AA Sbjct: 57 PEPIASAAAAAATVTSTGGGGGGGGSG------GGGGSSGNGGGGGGGGGGSNCNPNLAA 110 Query: 63 AAGAA 67 A+ + Sbjct: 111 ASNGS 115 Score = 33.9 bits (76), Expect = 0.56 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 5/49 (10%) Query: 17 SAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 + G GGGG G S G GGG GGGGS + ++A+ +G Sbjct: 73 TGGGGGGGGSGGGG-----GSSGNGGGGGGGGGGSNCNPNLAAASNGSG 116 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 57.4 bits (137), Expect = 5e-08 Identities = 30/55 (54%), Positives = 34/55 (61%), Gaps = 6/55 (10%) Query: 7 GGGGGGGSGPSAGSGGGGFG----GSAAVAAATASGGKSGGGSCGGGGSYSASSS 57 GGGGGGG G G GGGG G G+ AVAAA A+ + GG GGGG Y SS+ Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG--GGGGGYGGSSA 305 Score = 53.9 bits (128), Expect = 5e-07 Identities = 28/53 (52%), Positives = 31/53 (58%), Gaps = 2/53 (3%) Query: 7 GGGGGGGSGPSAGSGGGGFG--GSAAVAAATASGGKSGGGSCGGGGSYSASSS 57 GG GGGG G AG+GG G G +AA AAA A+GG GGG G Y SS Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS 312 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 21/80 (26%) Query: 7 GGGGGGGSGP------------------SAGSGGGGFGGSAAVAAATASGGKSGGGSC-- 46 GGGGGGG+G + G GGGG+GGS+A +S + GGG Sbjct: 264 GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG 323 Query: 47 -GGGGSYSASSSSSAAAAAG 65 GGGG+ S S +++ +AA G Sbjct: 324 PGGGGAASLSKAAAGSAAGG 343 Score = 50.1 bits (118), Expect = 8e-06 Identities = 27/56 (48%), Positives = 33/56 (58%), Gaps = 5/56 (8%) Query: 12 GGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAA 67 G S P AG GGGG GG SGG GGG G GG+ + + +++AAAAA AA Sbjct: 242 GYSRPGAGGGGGGGGGGGG-----GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA 292 Score = 34.7 bits (78), Expect = 0.33 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 4/74 (5%) Query: 11 GGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAVLP 70 GGG GP+A + GSAA A+ GG++G GG S +A+A AA P Sbjct: 161 GGGGGPAAVPEFNNYYGSAAPASG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219 Query: 71 VKKPKMEHVQADHE 84 M+ +Q HE Sbjct: 220 ---GSMDPLQNSHE 230 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 57.4 bits (137), Expect = 5e-08 Identities = 30/55 (54%), Positives = 34/55 (61%), Gaps = 6/55 (10%) Query: 7 GGGGGGGSGPSAGSGGGGFG----GSAAVAAATASGGKSGGGSCGGGGSYSASSS 57 GGGGGGG G G GGGG G G+ AVAAA A+ + GG GGGG Y SS+ Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG--GGGGGYGGSSA 305 Score = 53.9 bits (128), Expect = 5e-07 Identities = 28/53 (52%), Positives = 31/53 (58%), Gaps = 2/53 (3%) Query: 7 GGGGGGGSGPSAGSGGGGFG--GSAAVAAATASGGKSGGGSCGGGGSYSASSS 57 GG GGGG G AG+GG G G +AA AAA A+GG GGG G Y SS Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS 312 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 21/80 (26%) Query: 7 GGGGGGGSGP------------------SAGSGGGGFGGSAAVAAATASGGKSGGGSC-- 46 GGGGGGG+G + G GGGG+GGS+A +S + GGG Sbjct: 264 GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG 323 Query: 47 -GGGGSYSASSSSSAAAAAG 65 GGGG+ S S +++ +AA G Sbjct: 324 PGGGGAASLSKAAAGSAAGG 343 Score = 50.1 bits (118), Expect = 8e-06 Identities = 27/56 (48%), Positives = 33/56 (58%), Gaps = 5/56 (8%) Query: 12 GGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAA 67 G S P AG GGGG GG SGG GGG G GG+ + + +++AAAAA AA Sbjct: 242 GYSRPGAGGGGGGGGGGGG-----GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA 292 Score = 34.7 bits (78), Expect = 0.33 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 4/74 (5%) Query: 11 GGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAVLP 70 GGG GP+A + GSAA A+ GG++G GG S +A+A AA P Sbjct: 161 GGGGGPAAVPEFNNYYGSAAPASG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219 Query: 71 VKKPKMEHVQADHE 84 M+ +Q HE Sbjct: 220 ---GSMDPLQNSHE 230 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 57.4 bits (137), Expect = 5e-08 Identities = 30/55 (54%), Positives = 34/55 (61%), Gaps = 6/55 (10%) Query: 7 GGGGGGGSGPSAGSGGGGFG----GSAAVAAATASGGKSGGGSCGGGGSYSASSS 57 GGGGGGG G G GGGG G G+ AVAAA A+ + GG GGGG Y SS+ Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG--GGGGGYGGSSA 305 Score = 53.9 bits (128), Expect = 5e-07 Identities = 28/53 (52%), Positives = 31/53 (58%), Gaps = 2/53 (3%) Query: 7 GGGGGGGSGPSAGSGGGGFG--GSAAVAAATASGGKSGGGSCGGGGSYSASSS 57 GG GGGG G AG+GG G G +AA AAA A+GG GGG G Y SS Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS 312 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 21/80 (26%) Query: 7 GGGGGGGSGP------------------SAGSGGGGFGGSAAVAAATASGGKSGGGSC-- 46 GGGGGGG+G + G GGGG+GGS+A +S + GGG Sbjct: 264 GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG 323 Query: 47 -GGGGSYSASSSSSAAAAAG 65 GGGG+ S S +++ +AA G Sbjct: 324 PGGGGAASLSKAAAGSAAGG 343 Score = 50.1 bits (118), Expect = 8e-06 Identities = 27/56 (48%), Positives = 33/56 (58%), Gaps = 5/56 (8%) Query: 12 GGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAA 67 G S P AG GGGG GG SGG GGG G GG+ + + +++AAAAA AA Sbjct: 242 GYSRPGAGGGGGGGGGGGG-----GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA 292 Score = 34.7 bits (78), Expect = 0.33 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 4/74 (5%) Query: 11 GGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAVLP 70 GGG GP+A + GSAA A+ GG++G GG S +A+A AA P Sbjct: 161 GGGGGPAAVPEFNNYYGSAAPASG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219 Query: 71 VKKPKMEHVQADHE 84 M+ +Q HE Sbjct: 220 ---GSMDPLQNSHE 230 >gi|195972866 keratin 10 [Homo sapiens] Length = 584 Score = 56.2 bits (134), Expect = 1e-07 Identities = 28/65 (43%), Positives = 37/65 (56%), Gaps = 5/65 (7%) Query: 6 HGGGGGGGSGPSA---GSGGGGFGGSAAVAA--ATASGGKSGGGSCGGGGSYSASSSSSA 60 HGG GGG G + GS GGG+GG ++ ++SGG GG S GGGG Y SS Sbjct: 491 HGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGG 550 Query: 61 AAAAG 65 +++ G Sbjct: 551 SSSGG 555 Score = 52.8 bits (125), Expect = 1e-06 Identities = 27/61 (44%), Positives = 37/61 (60%), Gaps = 2/61 (3%) Query: 6 HGGGGGGG-SGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAA 64 HGG GG G S+G GGGG+GG ++ ++SGG GGGS GG S+S S +++ Sbjct: 522 HGGSSSGGYGGGSSGGGGGGYGGGSS-GGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSK 580 Query: 65 G 65 G Sbjct: 581 G 581 Score = 52.4 bits (124), Expect = 2e-06 Identities = 26/59 (44%), Positives = 31/59 (52%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 GGG GGGS SGGG GG + GG SGGGS GGG +SS +++G Sbjct: 470 GGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSG 528 Score = 50.1 bits (118), Expect = 8e-06 Identities = 27/63 (42%), Positives = 33/63 (52%), Gaps = 1/63 (1%) Query: 7 GGGGGGGSGPSAGSGGGGF-GGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 G GGG SG GS GG+ GGS+ GG SGGGS GGG SSS +++ Sbjct: 512 GYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSS 571 Query: 66 AAV 68 +V Sbjct: 572 GSV 574 Score = 49.7 bits (117), Expect = 1e-05 Identities = 26/62 (41%), Positives = 31/62 (50%), Gaps = 2/62 (3%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAA--VAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 GGG G G S G GGG GGS+ ++ GG SGGG GG S SSS G Sbjct: 474 GGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGG 533 Query: 66 AA 67 ++ Sbjct: 534 SS 535 Score = 47.8 bits (112), Expect = 4e-05 Identities = 26/64 (40%), Positives = 31/64 (48%), Gaps = 11/64 (17%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGG-----GGSYSASSSSSAA 61 G G GG G GS GGG+GG ++ GG SGGG GG GG Y SS + Sbjct: 455 GEGSSGGGGRGGGSFGGGYGG------GSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGS 508 Query: 62 AAAG 65 + G Sbjct: 509 SGGG 512 Score = 46.6 bits (109), Expect = 8e-05 Identities = 26/63 (41%), Positives = 31/63 (49%), Gaps = 3/63 (4%) Query: 6 HGGG---GGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAA 62 +GGG GG G S G GGG GG +SGG S G GGGS S SS++ Sbjct: 513 YGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSG 572 Query: 63 AAG 65 + G Sbjct: 573 SVG 575 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/70 (38%), Positives = 33/70 (47%), Gaps = 11/70 (15%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGG-----------GGSYSAS 55 GGG GGGS SGGG GGS++ +S G GGGS GG GGS S Sbjct: 496 GGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGG 555 Query: 56 SSSSAAAAAG 65 +++ G Sbjct: 556 GYGGGSSSGG 565 Score = 43.9 bits (102), Expect = 5e-04 Identities = 28/60 (46%), Positives = 29/60 (48%), Gaps = 10/60 (16%) Query: 9 GGGGGSGPSAG-------SGGGGFGGSAAVAAATASGGKSGGGSCGG---GGSYSASSSS 58 GGGG G S G SGGG GG +SGG GGGS GG GG Y SSS Sbjct: 460 GGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSS 519 Score = 42.7 bits (99), Expect = 0.001 Identities = 23/58 (39%), Positives = 26/58 (44%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 GG GG G G GGG F GS ++ S G S GG GGGS+ S G Sbjct: 68 GGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGG 125 Score = 41.6 bits (96), Expect = 0.003 Identities = 24/55 (43%), Positives = 32/55 (58%), Gaps = 9/55 (16%) Query: 5 KHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGG--GGSYSASSS 57 + GGGGGGG G GG GG +++ +++ G GG S GG GGS+S SS Sbjct: 15 RSGGGGGGG-------GCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSS 62 Score = 40.4 bits (93), Expect = 0.006 Identities = 30/77 (38%), Positives = 34/77 (44%), Gaps = 24/77 (31%) Query: 7 GGGGGGGSG-----------PSAGSGGGGFGGSAAVAAATASGGKSGGGSCG-------- 47 GGGGGGG G S GS GGGF S + + S G SGGG G Sbjct: 18 GGGGGGGCGGGGGVSSLRISSSKGSLGGGF-SSGGFSGGSFSRGSSGGGCFGGSSGGYGG 76 Query: 48 ----GGGSYSASSSSSA 60 GGGS+ S SS+ Sbjct: 77 LGGFGGGSFRGSYGSSS 93 Score = 40.4 bits (93), Expect = 0.006 Identities = 23/48 (47%), Positives = 26/48 (54%), Gaps = 3/48 (6%) Query: 6 HGGGGGGGSGPSAGS-GGGGFGGS--AAVAAATASGGKSGGGSCGGGG 50 +GG GG G G GS G FGGS + + GG GGGS GGGG Sbjct: 74 YGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGG 121 Score = 39.7 bits (91), Expect = 0.010 Identities = 23/50 (46%), Positives = 25/50 (50%), Gaps = 7/50 (14%) Query: 7 GGGGGG------GSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGG 50 GG GGG GS GS GG FGG + + GG GGG GGGG Sbjct: 78 GGFGGGSFRGSYGSSSFGGSYGGSFGG-GSFGGGSFGGGSFGGGGFGGGG 126 Score = 36.6 bits (83), Expect = 0.086 Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 6 HGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSAS 55 +GG GGGS GGG FGG GG GGG G GG S + Sbjct: 98 YGGSFGGGSFGGGSFGGGSFGGGG--FGGGGFGGGFGGGFGGDGGLLSGN 145 Score = 35.4 bits (80), Expect = 0.19 Identities = 15/33 (45%), Positives = 21/33 (63%) Query: 33 AATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 +++ SGG GGG CGGGG S+ SS+ + G Sbjct: 12 SSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLG 44 Score = 34.7 bits (78), Expect = 0.33 Identities = 19/42 (45%), Positives = 20/42 (47%), Gaps = 6/42 (14%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGG 49 GG GGS GGG FGG + GG GGG GGG Sbjct: 95 GGSYGGSFGGGSFGGGSFGG------GSFGGGGFGGGGFGGG 130 Score = 31.6 bits (70), Expect = 2.8 Identities = 15/34 (44%), Positives = 16/34 (47%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGK 40 GGG GG G G GGGFGG SG + Sbjct: 113 GGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNE 146 >gi|109255251 loricrin [Homo sapiens] Length = 312 Score = 53.1 bits (126), Expect = 9e-07 Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 1/62 (1%) Query: 7 GGGGGGGSGPSAG-SGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 GG GGG SG G SGGGG+ G ++ GG G G CGGG S S ++ G Sbjct: 40 GGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGG 99 Query: 66 AA 67 + Sbjct: 100 GS 101 Score = 50.1 bits (118), Expect = 8e-06 Identities = 29/66 (43%), Positives = 33/66 (50%), Gaps = 8/66 (12%) Query: 9 GGGGGSGPSAGSGGGGF----GGSAAVAAATASGGKSGGG----SCGGGGSYSASSSSSA 60 GGG G G S G GGGG GGS + GG SGGG S GGGGS SS Sbjct: 61 GGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGG 120 Query: 61 AAAAGA 66 ++ G+ Sbjct: 121 SSGGGS 126 Score = 49.7 bits (117), Expect = 1e-05 Identities = 31/78 (39%), Positives = 37/78 (47%), Gaps = 8/78 (10%) Query: 2 APQKHGGGGGGGSGPSAGSG---GGGFGGSAAVAAATASGGK----SGGGS-CGGGGSYS 53 APQ GGG G G S GSG GG GGS+ ++ G SGGGS CGGG S Sbjct: 220 APQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGG 279 Query: 54 ASSSSSAAAAAGAAVLPV 71 SS + +P+ Sbjct: 280 GGGGSSVGGSGSGKGVPI 297 Score = 49.3 bits (116), Expect = 1e-05 Identities = 28/62 (45%), Positives = 31/62 (50%), Gaps = 2/62 (3%) Query: 5 KHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASG-GKSGGGSCGGGGSYSASSSSSAAAA 63 K GGGGGG G S G G G FGG + ++ SG G SGGG GGG SS Sbjct: 18 KTSGGGGGGGG-SGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGG 76 Query: 64 AG 65 G Sbjct: 77 IG 78 Score = 49.3 bits (116), Expect = 1e-05 Identities = 23/60 (38%), Positives = 26/60 (43%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGA 66 GGGG GG G GGG GGS+ + GG GG CGGG S G+ Sbjct: 25 GGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGS 84 Score = 48.1 bits (113), Expect = 3e-05 Identities = 30/70 (42%), Positives = 34/70 (48%), Gaps = 9/70 (12%) Query: 7 GGGGGGGSGPSA-GSGGGGFGGSAAVA---AATASGGKSGGGS-C----GGGGSYSASSS 57 GGGG G G SGGGGF G A +SGG SGGGS C GGGGS S Sbjct: 132 GGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSG 191 Query: 58 SSAAAAAGAA 67 + G++ Sbjct: 192 GGSGCGGGSS 201 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/72 (38%), Positives = 34/72 (47%), Gaps = 12/72 (16%) Query: 7 GGGGGGGSGPSAG--------SGGGGFGGSAAVAAATASGG----KSGGGSCGGGGSYSA 54 GGGGGGG G G SGGGG G + ++ GG SGGG GGGS Sbjct: 70 GGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCF 129 Query: 55 SSSSSAAAAAGA 66 SS ++ G+ Sbjct: 130 SSGGGGSSGGGS 141 Score = 46.6 bits (109), Expect = 8e-05 Identities = 28/65 (43%), Positives = 31/65 (47%), Gaps = 3/65 (4%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASS---SSSAAAA 63 GGGG G G S GGG G + +SGG SG S GGGGS S SS Sbjct: 92 GGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGF 151 Query: 64 AGAAV 68 +G AV Sbjct: 152 SGQAV 156 Score = 45.8 bits (107), Expect = 1e-04 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 6/68 (8%) Query: 6 HGGGGGGGSGPSAGSGGGGFGGSAAVAAATAS------GGKSGGGSCGGGGSYSASSSSS 59 + GGG G G S+G G G+ S V + + GG SGGG GG G +S+ Sbjct: 189 YSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGG 248 Query: 60 AAAAAGAA 67 ++ G + Sbjct: 249 SSGCGGGS 256 Score = 43.5 bits (101), Expect = 7e-04 Identities = 25/66 (37%), Positives = 30/66 (45%), Gaps = 5/66 (7%) Query: 7 GGGGGGGSGPSAGSGG-----GGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAA 61 GGGGGG G GSGG GG G S + +SGG G GGG S S + Sbjct: 71 GGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFS 130 Query: 62 AAAGAA 67 + G + Sbjct: 131 SGGGGS 136 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 14/73 (19%) Query: 9 GGGGGSGPSAG---SGGGGFGGSAA-------VAAATASGGKSG----GGSCGGGGSYSA 54 GGGG SG +G SGGGGF G A V++ +SGG SG GG G YS Sbjct: 132 GGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSG 191 Query: 55 SSSSSAAAAAGAA 67 S ++G + Sbjct: 192 GGSGCGGGSSGGS 204 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 5/50 (10%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASS 56 GG GGGSG + GGGG +V + G GGGS GG GS SS Sbjct: 167 GGSSGGGSGCFSSGGGGG-----SVCGYSGGGSGCGGGSSGGSGSGYVSS 211 Score = 40.4 bits (93), Expect = 0.006 Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 17 SAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAA 67 ++G GGGG GGS GG SGGGS G G YS S G + Sbjct: 19 TSGGGGGG-GGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGS 68 Score = 39.3 bits (90), Expect = 0.013 Identities = 27/79 (34%), Positives = 31/79 (39%), Gaps = 20/79 (25%) Query: 7 GGGGGGGSGPSA------------GSGGGGFGGSAAVAAATASGG-------KSGGGSCG 47 GGG GGGS S G GGG GG GG GGGS G Sbjct: 39 GGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSG 98 Query: 48 GG-GSYSASSSSSAAAAAG 65 GG G +S+ S ++G Sbjct: 99 GGSGCFSSGGGGSGCFSSG 117 >gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] Length = 474 Score = 52.8 bits (125), Expect = 1e-06 Identities = 35/85 (41%), Positives = 44/85 (51%), Gaps = 19/85 (22%) Query: 6 HGGGGGGGSGPSAGSGGGGFGGSAAVAAAT-------ASGGKSGG-----------GSCG 47 HGGGGGGGS + G GGG GG A A +GG GG G G Sbjct: 166 HGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGG 225 Query: 48 GGGSYSASSSSSAAAAAG-AAVLPV 71 GG + +A+++S AA AG AA+LP+ Sbjct: 226 GGKAAAAAAASFAAEQAGAAALLPL 250 Score = 48.1 bits (113), Expect = 3e-05 Identities = 32/84 (38%), Positives = 41/84 (48%), Gaps = 21/84 (25%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVA----------AATASGGKSGG-----------GS 45 GG GGGG G S+ +GGGG G S A + +GG GG G Sbjct: 164 GGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGG 223 Query: 46 CGGGGSYSASSSSSAAAAAGAAVL 69 GGG + +A+++S AA AGAA L Sbjct: 224 GGGGKAAAAAAASFAAEQAGAAAL 247 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/77 (41%), Positives = 35/77 (45%), Gaps = 12/77 (15%) Query: 5 KHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAA 64 K GG GGGG G GGGG G S A GG GG S GG S A S + A Sbjct: 157 KVGGSGGGGHG-----GGGGGGSSNA-------GGGGGGASGGGANSKPAQKKSCGSKVA 204 Query: 65 GAAVLPVKKPKMEHVQA 81 G A V KP + + A Sbjct: 205 GGAGGGVSKPHAKLILA 221 Score = 32.7 bits (73), Expect = 1.2 Identities = 21/60 (35%), Positives = 30/60 (50%) Query: 9 GGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAV 68 GGGGG +A + A AA G + S + SAS+S+S+AA+A AA+ Sbjct: 222 GGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAAL 281 Score = 30.8 bits (68), Expect = 4.7 Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 7/61 (11%) Query: 20 SGGGGFGGSAAVAAATASGGKSGGGS-------CGGGGSYSASSSSSAAAAAGAAVLPVK 72 SG SAA ++ G GGS GGGGS +A A+ GA P + Sbjct: 136 SGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQ 195 Query: 73 K 73 K Sbjct: 196 K 196 Score = 30.4 bits (67), Expect = 6.2 Identities = 16/57 (28%), Positives = 29/57 (50%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAA 64 G S P+AG G A++ AA+ + + + S+S+SSSSS ++++ Sbjct: 341 GRSSAASSPAAGRSPADHRGYASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSS 397 >gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo sapiens] Length = 3969 Score = 52.4 bits (124), Expect = 2e-06 Identities = 38/105 (36%), Positives = 49/105 (46%), Gaps = 19/105 (18%) Query: 3 PQKHGGGGGGGS------------------GPSAGSGGGGFGGSA-AVAAATASGGKSGG 43 P GGGGGGG GP G GG G S AVAAA A+ G SG Sbjct: 13 PGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGA 72 Query: 44 GSCGGGGSYSASSSSSAAAAAGAAVLPVKKPKMEHVQADHELFLQ 88 G GG + SA+SSSSA++++ ++ P + V + LQ Sbjct: 73 GVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQ 117 Score = 30.0 bits (66), Expect = 8.1 Identities = 23/76 (30%), Positives = 30/76 (39%), Gaps = 15/76 (19%) Query: 8 GGGGGGSGPS----------AGSGGGGFGG-----SAAVAAATASGGKSGGGSCGGGGSY 52 GGGG G+ PS AGS G G G SAA +++ +S S + G Sbjct: 47 GGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALL 106 Query: 53 SASSSSSAAAAAGAAV 68 AA AA+ Sbjct: 107 RVGPGFDAALQVSAAI 122 >gi|55956899 keratin 9 [Homo sapiens] Length = 623 Score = 52.4 bits (124), Expect = 2e-06 Identities = 25/58 (43%), Positives = 29/58 (50%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 GG GG G +GSGGG GG + SGG GG S G GG+Y S S + G Sbjct: 514 GGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGG 571 Score = 51.6 bits (122), Expect = 3e-06 Identities = 28/53 (52%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAA-VAAATASGGKSGGGSCGGGGSYSASSSS 58 G GGG G G S GSGGG GGS + SGG SGGG GG GS S S Sbjct: 533 GYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGS 585 Score = 51.2 bits (121), Expect = 3e-06 Identities = 27/62 (43%), Positives = 32/62 (51%), Gaps = 2/62 (3%) Query: 7 GGGGGGGSGPSAGSGG--GGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAA 64 GGG GGGSG GSGG GG GS + GG GG S G GG +S S + + Sbjct: 503 GGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGS 562 Query: 65 GA 66 G+ Sbjct: 563 GS 564 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/55 (50%), Positives = 29/55 (52%), Gaps = 4/55 (7%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGS---YSASSSS 58 G GGG G G GSGGG GGS + SGG GGGS GGGS Y S S Sbjct: 525 GSGGGSGGGYGGGSGGGHSGGSGG-GHSGGSGGNYGGGSGSGGGSGGGYGGGSGS 578 Score = 47.8 bits (112), Expect = 4e-05 Identities = 25/62 (40%), Positives = 29/62 (46%) Query: 6 HGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 +G G GGSG S G GG G G + SGG GGGS GGGS S +G Sbjct: 485 YGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSG 544 Query: 66 AA 67 + Sbjct: 545 GS 546 Score = 47.8 bits (112), Expect = 4e-05 Identities = 27/61 (44%), Positives = 32/61 (52%), Gaps = 2/61 (3%) Query: 7 GGGGGGGSGPSAGSGGGGFGGS-AAVAAATASGGKSGGGSCGG-GGSYSASSSSSAAAAA 64 G GGGGSG G G G GGS + + SGG SGGG GG GG +S S + + Sbjct: 495 GSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGS 554 Query: 65 G 65 G Sbjct: 555 G 555 Score = 47.0 bits (110), Expect = 6e-05 Identities = 28/58 (48%), Positives = 31/58 (53%), Gaps = 6/58 (10%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGG---GGSYSASSSSSAA 61 GG GGGSG GSGGG GGS + SGG GGGS G GGSY +S + Sbjct: 555 GGNYGGGSGSGGGSGGGYGGGSGSRGG---SGGSHGGGSGFGGESGGSYGGGEEASGS 609 Score = 46.2 bits (108), Expect = 1e-04 Identities = 26/55 (47%), Positives = 29/55 (52%), Gaps = 2/55 (3%) Query: 7 GGGGGGGSGPSAGSGG--GGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSS 59 GGG GGGSG GSGG GG G + + GG+ GS GG G S SS S Sbjct: 569 GGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSSHS 623 Score = 44.7 bits (104), Expect = 3e-04 Identities = 31/65 (47%), Positives = 32/65 (49%), Gaps = 7/65 (10%) Query: 5 KHGGGGGGGSGPSAGSGG-GGFGGSAAVAAATASGGKSGGGS---CGGGGSYSASSSSSA 60 K G GG GGSG S G G GG GGS SGG GGGS G GGSY S S Sbjct: 472 KIGLGGRGGSGGSYGRGSRGGSGGS---YGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGG 528 Query: 61 AAAAG 65 + G Sbjct: 529 GSGGG 533 Score = 44.3 bits (103), Expect = 4e-04 Identities = 28/68 (41%), Positives = 31/68 (45%), Gaps = 10/68 (14%) Query: 9 GGGGGSGPSAGSGGGGFGGSAAVAAATASGGKS---------GGGSCGG-GGSYSASSSS 58 GGG G G SA S GGGFGG + + GG S GGGS GG GG Y + Sbjct: 74 GGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGG 133 Query: 59 SAAAAAGA 66 GA Sbjct: 134 FGGFGGGA 141 Score = 42.7 bits (99), Expect = 0.001 Identities = 31/75 (41%), Positives = 35/75 (46%), Gaps = 16/75 (21%) Query: 7 GGGGGG--------GSGPSA--GSGGGGF------GGSAAVAAATASGGKSGGGSCGGGG 50 GGGGGG G G S G GGGG GGS +A++ GG GGGS G GG Sbjct: 40 GGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGG 99 Query: 51 SYSASSSSSAAAAAG 65 + SSS G Sbjct: 100 ASGGGYSSSGGFGGG 114 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/69 (42%), Positives = 35/69 (50%), Gaps = 19/69 (27%) Query: 7 GGGGGGGSGPS--------AGSGGGGFGGSAAVAAATASG-----GKSGGGSCG------ 47 GGGGG GSG S + SGGGG GG + ++ G G+ GGGS G Sbjct: 17 GGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGG 76 Query: 48 GGGSYSASS 56 GG +SASS Sbjct: 77 SGGGFSASS 85 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 3/64 (4%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCG---GGGSYSASSSSSAAAA 63 GG GG G +G G GG GS + + GG GG G GGGS S S Sbjct: 491 GGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGH 550 Query: 64 AGAA 67 +G + Sbjct: 551 SGGS 554 Score = 40.8 bits (94), Expect = 0.005 Identities = 30/79 (37%), Positives = 37/79 (46%), Gaps = 18/79 (22%) Query: 5 KHGGGGGGGSGP------------SAGSGGGG--FGGSAAVAAATAS-GGKSGGGSCG-- 47 + GGGGGGG G S+G GGGG F S+ ++ G+ GGGS G Sbjct: 13 RSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYS 72 Query: 48 -GGGSYSASSSSSAAAAAG 65 GGGS S+SS G Sbjct: 73 YGGGSGGGFSASSLGGGFG 91 Score = 40.4 bits (93), Expect = 0.006 Identities = 23/61 (37%), Positives = 25/61 (40%), Gaps = 2/61 (3%) Query: 7 GGGGGGGSGPSAGSGG--GGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAA 64 G GG G G GSGG GG G + S G SGG GG GS S + Sbjct: 480 GSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSG 539 Query: 65 G 65 G Sbjct: 540 G 540 Score = 39.7 bits (91), Expect = 0.010 Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 5/57 (8%) Query: 7 GGGGGGGSGP-SAGSGGGGFGGSAAVAAATASGGKSGGG--SCGGGGSYSASSSSSA 60 G GGG G G S G GG GG + SGG GGG + G GG Y S S+ Sbjct: 567 GSGGGYGGGSGSRGGSGGSHGGGSGFGG--ESGGSYGGGEEASGSGGGYGGGSGKSS 621 Score = 37.0 bits (84), Expect = 0.066 Identities = 26/64 (40%), Positives = 26/64 (40%), Gaps = 13/64 (20%) Query: 7 GGGGGGGSGPSAGSGG-----GGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAA 61 GG GGG G SGG GGFGG GG SGGG GG GS Sbjct: 88 GGFGGGSRGFGGASGGGYSSSGGFGG--------GFGGGSGGGFGGGYGSGFGGFGGFGG 139 Query: 62 AAAG 65 A G Sbjct: 140 GAGG 143 Score = 36.6 bits (83), Expect = 0.086 Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 8/60 (13%) Query: 7 GGGGGGGSGPSAGSGG-------GGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSS 59 GG GGG S G GG GGFGG + GG GG G GG +A+ S+ Sbjct: 98 GGASGGGYSSSGGFGGGFGGGSGGGFGGGYG-SGFGGFGGFGGGAGGGDGGILTANEKST 156 Score = 34.3 bits (77), Expect = 0.43 Identities = 24/48 (50%), Positives = 26/48 (54%), Gaps = 10/48 (20%) Query: 6 HGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYS 53 HGGG G G G S GS GGG A+ SGG GGGS G S+S Sbjct: 586 HGGGSGFG-GESGGSYGGG-------EEASGSGGGYGGGS--GKSSHS 623 >gi|194018511 keratin 77 [Homo sapiens] Length = 578 Score = 51.2 bits (121), Expect = 3e-06 Identities = 27/60 (45%), Positives = 31/60 (51%), Gaps = 3/60 (5%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATA---SGGKSGGGSCGGGGSYSASSSSSAAAA 63 GGGG GSG G GGG+GG + A SGG G G GGGGSY S S ++ Sbjct: 501 GGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYGGSGRSGRGSS 560 Score = 35.4 bits (80), Expect = 0.19 Identities = 17/41 (41%), Positives = 18/41 (43%) Query: 10 GGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGG 50 G SG G G GGFGG + G GGG GG G Sbjct: 76 GRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAG 116 Score = 35.0 bits (79), Expect = 0.25 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 15/109 (13%) Query: 7 GGGGGG-----GSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAA 61 GG GGG GS + G GGGGFGG+ + GG G C GG + + S Sbjct: 89 GGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGG--FGPYCPPGGIQEVTINQSLL 146 Query: 62 AAAGAAVLP----VKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLI 106 V P +K + E + + F +K RFL +N + Sbjct: 147 EPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDK----VRFLEQQNQV 191 >gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma) [Homo sapiens] Length = 526 Score = 51.2 bits (121), Expect = 3e-06 Identities = 26/50 (52%), Positives = 27/50 (54%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASS 56 GGG GGG G SGGGG GG G SGGG GGGG Y+ SS Sbjct: 187 GGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS 236 Score = 39.7 bits (91), Expect = 0.010 Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 1/46 (2%) Query: 4 QKHGGGGGGGSGPSAGSGGGGFG-GSAAVAAATASGGKSGGGSCGG 48 Q GG G GGSG G GGGG+ S GG+ G G GG Sbjct: 211 QDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256 Score = 38.1 bits (87), Expect = 0.030 Identities = 22/54 (40%), Positives = 26/54 (48%), Gaps = 5/54 (9%) Query: 3 PQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGG-----SCGGGGS 51 PQ +G S G GGGG G ++ +SGG SGGG GGGGS Sbjct: 152 PQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGS 205 Score = 37.0 bits (84), Expect = 0.066 Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 5/44 (11%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGG 50 GG G GG G G GG+GG + GG+ G S GGGG Sbjct: 379 GGNGRGGRGRGGPMGRGGYGGGGS-----GGGGRGGFPSGGGGG 417 Score = 33.5 bits (75), Expect = 0.73 Identities = 19/52 (36%), Positives = 24/52 (46%) Query: 9 GGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA 60 G G + ++ SGGGG GG S SGGGS GG G+ S + Sbjct: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGS 205 Score = 32.0 bits (71), Expect = 2.1 Identities = 16/29 (55%), Positives = 16/29 (55%), Gaps = 7/29 (24%) Query: 3 PQKHGGGGGGGSG-------PSAGSGGGG 24 P GG GGGGSG PS G GGGG Sbjct: 391 PMGRGGYGGGGSGGGGRGGFPSGGGGGGG 419 Score = 31.6 bits (70), Expect = 2.8 Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 6/59 (10%) Query: 7 GGGGGGGSGPSAGSG------GGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSS 59 GGGGGGG + G GGG GG + + G GG G + + +S Sbjct: 224 GGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNS 282 >gi|47132620 keratin 2 [Homo sapiens] Length = 639 Score = 51.2 bits (121), Expect = 3e-06 Identities = 33/68 (48%), Positives = 38/68 (55%), Gaps = 7/68 (10%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGK--SGGGSCGG---GGSYSA--SSSSS 59 G G GGGSG GSGGG GGS + + GGK SGGGS GG GG Y + SSS Sbjct: 562 GYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSS 621 Query: 60 AAAAAGAA 67 ++G A Sbjct: 622 VKGSSGEA 629 Score = 49.3 bits (116), Expect = 1e-05 Identities = 25/61 (40%), Positives = 31/61 (50%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAA 67 G GGG G S GG G GG + + GG S GG G GG S+S S+ A G++ Sbjct: 574 GSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSS 633 Query: 68 V 68 V Sbjct: 634 V 634 Score = 48.1 bits (113), Expect = 3e-05 Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 7 GGGGGGGSGPSAGSG-GGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 GG GGGGS G G GGG GG + G SGGG GGG +S+ S +++G Sbjct: 550 GGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSG 609 Score = 45.4 bits (106), Expect = 2e-04 Identities = 22/44 (50%), Positives = 26/44 (59%), Gaps = 1/44 (2%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATA-SGGKSGGGSCGGG 49 GGGGG G+ G GGGFGG ++ + SGG GGG GGG Sbjct: 78 GGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGG 121 Score = 42.7 bits (99), Expect = 0.001 Identities = 28/79 (35%), Positives = 30/79 (37%), Gaps = 20/79 (25%) Query: 5 KHGGGGGGGSGPSAGS------------------GGGGFGGSAAVAAATASGGKSGGGSC 46 +HGGGGGG G GS GGGGFG AA GG GG S Sbjct: 45 RHGGGGGGFGGGGFGSRSLVGLGGTKSISISVAGGGGGFG--AAGGFGGRGGGFGGGSSF 102 Query: 47 GGGGSYSASSSSSAAAAAG 65 GGG +S G Sbjct: 103 GGGSGFSGGGFGGGGFGGG 121 Score = 42.0 bits (97), Expect = 0.002 Identities = 21/56 (37%), Positives = 24/56 (42%) Query: 9 GGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAA 64 G GGSG GGG+G SGG S GGS GGG S S+ + Sbjct: 547 GSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGS 602 Score = 40.4 bits (93), Expect = 0.006 Identities = 22/59 (37%), Positives = 25/59 (42%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 G G G +GS GG GG + SGG SGG GGGS S S + G Sbjct: 535 GSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGG 593 Score = 39.7 bits (91), Expect = 0.010 Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 16/109 (14%) Query: 8 GGGGGGSGPSAGSGG------GGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAA 61 GGG G SG G GG GGFGG V GG GG GG + S + S Sbjct: 103 GGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGY--PGGIHEVSVNQSLL 160 Query: 62 AAAGAAVLP----VKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLI 106 V P VK + E ++ + F +K RFL +N + Sbjct: 161 QPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDK----VRFLEQQNQV 205 Score = 39.7 bits (91), Expect = 0.010 Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 6/63 (9%) Query: 9 GGGGGSGPSAGSGGGGFGGSAAVAA----ATASGGKSGGGSCGGGGSYSASSSSSAAAAA 64 GG GG G S SGGG GS++ + + + GG GGGS GGG S S + Sbjct: 519 GGSGGRGSS--SGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSG 576 Query: 65 GAA 67 G + Sbjct: 577 GGS 579 Score = 37.4 bits (85), Expect = 0.051 Identities = 22/50 (44%), Positives = 25/50 (50%), Gaps = 8/50 (16%) Query: 9 GGGGGSGPSAGSGG-----GG---FGGSAAVAAATASGGKSGGGSCGGGG 50 GGGGG G + G GG GG FGG + + GG GGG GG G Sbjct: 78 GGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFG 127 Score = 37.0 bits (84), Expect = 0.066 Identities = 23/52 (44%), Positives = 29/52 (55%), Gaps = 5/52 (9%) Query: 7 GGGGGGGSGPSAGS---GGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSAS 55 GGGGGG G S+GS GG +++ + + GG GGG GGGG S S Sbjct: 13 GGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGG--GGGGFGGGGFGSRS 62 Score = 31.2 bits (69), Expect = 3.6 Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 6/43 (13%) Query: 5 KHGGGGG--GGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGS 45 KH GGG GGS G G GG GGS++V S G++ G S Sbjct: 595 KHSSGGGSRGGSSSGGGYGSGG-GGSSSV---KGSSGEAFGSS 633 Score = 30.8 bits (68), Expect = 4.7 Identities = 16/30 (53%), Positives = 18/30 (60%) Query: 28 SAAVAAATASGGKSGGGSCGGGGSYSASSS 57 S+ VA+ A GG G GS GGG S SSS Sbjct: 509 SSNVASKAAFGGSGGRGSSSGGGYSSGSSS 538 Score = 30.4 bits (67), Expect = 6.2 Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 7/56 (12%) Query: 17 SAGSGGGG-----FGGSAAVAAATASGGKSGG--GSCGGGGSYSASSSSSAAAAAG 65 +A G GG GG ++ +++ SGG+ G G GGGGS S S + G Sbjct: 516 AAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGG 571 >gi|45439359 triple functional domain (PTPRF interacting) [Homo sapiens] Length = 3097 Score = 50.8 bits (120), Expect = 4e-06 Identities = 28/52 (53%), Positives = 29/52 (55%), Gaps = 4/52 (7%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSS 58 GGGGGGGSG S G GG G GG A + SG G SCGG S S S S Sbjct: 2292 GGGGGGGSGGSGGGGGSGGGG----APSGGSGHSGGPSSCGGAPSTSRSRPS 2339 Score = 40.4 bits (93), Expect = 0.006 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 6/59 (10%) Query: 17 SAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAVLPVKKPK 75 S G GGGG GGS GG GGG+ GG +S SS A + + P + P+ Sbjct: 2291 SGGGGGGGSGGSG------GGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSRIPQ 2343 Score = 32.7 bits (73), Expect = 1.2 Identities = 52/200 (26%), Positives = 75/200 (37%), Gaps = 33/200 (16%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAA----- 62 G GG + P+A SG AAA ++ G GG G G +A + AA Sbjct: 3 GSSGGAAAPAASSGP---------AAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSG 53 Query: 63 ------AAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLT 116 VLP+ K K+ ++ + P + + I L R ++ Sbjct: 54 FRKNDEMKAMDVLPILKEKVAYLSGGRD----KRGGPILTFPARSNHDRIRQEDLRRLIS 109 Query: 117 YMSHRNSRTNIKRK-TFKVDDMLSKVEKMKG----EQESHSLSAHLQLTF--TGFFHK-- 167 Y++ S KR T VD SK + +K QES H+ L F+ K Sbjct: 110 YLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQR 169 Query: 168 NDKPSPNSENEQNSVTLEVL 187 + S E E N V+LE L Sbjct: 170 TNFGSSKFEFETNMVSLEGL 189 >gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens] Length = 483 Score = 50.4 bits (119), Expect = 6e-06 Identities = 29/61 (47%), Positives = 33/61 (54%), Gaps = 6/61 (9%) Query: 3 PQKHGGGGGGGSGPSAGSGGGGFGGSAAVAA------ATASGGKSGGGSCGGGGSYSASS 56 P GGGGGGG G SA GG GG A+V A A++SGG GG GG G A + Sbjct: 25 PGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGGGSGGPGAGT 84 Query: 57 S 57 S Sbjct: 85 S 85 Score = 43.9 bits (102), Expect = 5e-04 Identities = 26/70 (37%), Positives = 32/70 (45%), Gaps = 10/70 (14%) Query: 8 GGGGGGSG---------PSAGSGGGGFG-GSAAVAAATASGGKSGGGSCGGGGSYSASSS 57 GGG GGSG P G GGGG G G +A GGK+ G+ GGG S+S Sbjct: 8 GGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGG 67 Query: 58 SSAAAAAGAA 67 + G + Sbjct: 68 GPGGSGGGGS 77 Score = 43.5 bits (101), Expect = 7e-04 Identities = 22/63 (34%), Positives = 27/63 (42%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAA 67 GGGGGG G G G GG+ A+ + G G S GGG + S AG + Sbjct: 26 GGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGGGSGGPGAGTS 85 Query: 68 VLP 70 P Sbjct: 86 FPP 88 Score = 38.1 bits (87), Expect = 0.030 Identities = 24/55 (43%), Positives = 27/55 (49%), Gaps = 6/55 (10%) Query: 13 GSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAA 67 G GPS GGG GGS A T+S + GGG GGGG S+S G A Sbjct: 3 GGGPS----GGGPGGSGR--ARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKA 51 Score = 33.1 bits (74), Expect = 0.95 Identities = 20/58 (34%), Positives = 21/58 (36%), Gaps = 1/58 (1%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 GGG G GP GSG A GG GGS G G +S A G Sbjct: 3 GGGPSGGGPG-GSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGG 59 Score = 32.3 bits (72), Expect = 1.6 Identities = 20/58 (34%), Positives = 25/58 (43%), Gaps = 4/58 (6%) Query: 11 GGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAV 68 GGG GG G G A ++ GG GGG G GGS S + A+ A+ Sbjct: 3 GGGPSG----GGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAM 56 Score = 30.8 bits (68), Expect = 4.7 Identities = 19/41 (46%), Positives = 20/41 (48%), Gaps = 2/41 (4%) Query: 7 GGGGGGGS--GPSAGSGGGGFGGSAAVAAATASGGKSGGGS 45 GGG G S G GSGGGG GG A + G K G S Sbjct: 57 GGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDS 97 >gi|4502565 calpain, small subunit 1 [Homo sapiens] Length = 268 Score = 50.1 bits (118), Expect = 8e-06 Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Query: 5 KHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSA----SSSSSA 60 K GGGGGGG G G G GG + A GG GGG GGGG +A SA Sbjct: 9 KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISA 68 Query: 61 AAAAGAAVLPVKKPKMEH 78 + A A P P H Sbjct: 69 ISEAAAQYNPEPPPPRTH 86 >gi|51599151 calpain, small subunit 1 [Homo sapiens] Length = 268 Score = 50.1 bits (118), Expect = 8e-06 Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Query: 5 KHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSA----SSSSSA 60 K GGGGGGG G G G GG + A GG GGG GGGG +A SA Sbjct: 9 KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISA 68 Query: 61 AAAAGAAVLPVKKPKMEH 78 + A A P P H Sbjct: 69 ISEAAAQYNPEPPPPRTH 86 >gi|119395750 keratin 1 [Homo sapiens] Length = 644 Score = 49.7 bits (117), Expect = 1e-05 Identities = 29/65 (44%), Positives = 37/65 (56%), Gaps = 10/65 (15%) Query: 7 GGGGGGGSGPSA--------GSGGGGFGGSAAVAAATASGGKSGG--GSCGGGGSYSASS 56 GGGGG GSG S+ GSGGGG GG + + +S G GG GS GGGG + + Sbjct: 520 GGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYG 579 Query: 57 SSSAA 61 S S++ Sbjct: 580 SGSSS 584 Score = 49.7 bits (117), Expect = 1e-05 Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 7/66 (10%) Query: 6 HGGGGGGGSGPSAGSG-------GGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSS 58 +G GGGGG S GSG GG GG + SGG S GGS GG GS S S Sbjct: 566 YGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKS 625 Query: 59 SAAAAA 64 S +++ Sbjct: 626 SGGSSS 631 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/72 (41%), Positives = 36/72 (50%), Gaps = 10/72 (13%) Query: 7 GGGGGGG------SGPSAGSGGG--GFGGSAAVAAATASGGKSGG--GSCGGGGSYSASS 56 GGGGGGG G S GSGGG G GG + SG SGG G GGGG S+ Sbjct: 542 GGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGG 601 Query: 57 SSSAAAAAGAAV 68 S ++G ++ Sbjct: 602 RGSGGGSSGGSI 613 Score = 48.5 bits (114), Expect = 2e-05 Identities = 41/155 (26%), Positives = 67/155 (43%), Gaps = 19/155 (12%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGG-------GGSYSASSSSS 59 GGG GGG G GGGGFGG + GG GGG GG GG + + S Sbjct: 101 GGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQS 160 Query: 60 AAAAAGAAVLP----VKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTL 115 + P VK + E +++ + F +K RFL +N + + L Sbjct: 161 LLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDK----VRFLEQQNQV--LQTKWEL 214 Query: 116 TYMSHRNSRTNIKRKTFK--VDDMLSKVEKMKGEQ 148 ++RT+ F+ ++++ +V+++K +Q Sbjct: 215 LQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQ 249 Score = 48.5 bits (114), Expect = 2e-05 Identities = 26/61 (42%), Positives = 32/61 (52%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGA 66 GGGGG GS S S GG GGS ++ G SGGGS GG SSS ++ G+ Sbjct: 570 GGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGS 629 Query: 67 A 67 + Sbjct: 630 S 630 Score = 48.1 bits (113), Expect = 3e-05 Identities = 26/59 (44%), Positives = 31/59 (52%) Query: 9 GGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAA 67 G GGGS S G GGGG G + ++ SGG S G GGGG S S SS+ G + Sbjct: 533 GSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGS 591 Score = 47.0 bits (110), Expect = 6e-05 Identities = 27/65 (41%), Positives = 33/65 (50%), Gaps = 6/65 (9%) Query: 7 GGGGGGGSGPSAGSGGGGF---GGSAAVAAATASGGK---SGGGSCGGGGSYSASSSSSA 60 GGGG G G S GSGGG + GG + SGG SGGGS G GG S + Sbjct: 521 GGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGS 580 Query: 61 AAAAG 65 +++G Sbjct: 581 GSSSG 585 Score = 45.4 bits (106), Expect = 2e-04 Identities = 23/44 (52%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGG 50 GGG GGG G GGGGFGG + G SGGG GGGG Sbjct: 91 GGGYGGGGFGGGGFGGGGFGG-GGIGGGGFGGFGSGGGGFGGGG 133 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/57 (43%), Positives = 25/57 (43%), Gaps = 6/57 (10%) Query: 9 GGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 GGG GSG G GGGGFGG GG GGG GGGG S G Sbjct: 83 GGGRGSGFGGGYGGGGFGGGG------FGGGGFGGGGIGGGGFGGFGSGGGGFGGGG 133 Score = 44.3 bits (103), Expect = 4e-04 Identities = 24/59 (40%), Positives = 28/59 (47%), Gaps = 1/59 (1%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 GGG GG G GSGG + GS + + GG G GS G GGS S S + G Sbjct: 514 GGGSRGGGGGGYGSGGSSY-GSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGG 571 Score = 41.6 bits (96), Expect = 0.003 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 14/76 (18%) Query: 4 QKHGGGGG-----GGSGPSAGSGGG-------GFGGSAAVAAATASGGKSGGGSCG--GG 49 ++ GGGGG GG G S G+GGG GGS +++ + A GG G G G GG Sbjct: 37 RRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGG 96 Query: 50 GSYSASSSSSAAAAAG 65 G + G Sbjct: 97 GGFGGGGFGGGGFGGG 112 Score = 41.2 bits (95), Expect = 0.004 Identities = 24/52 (46%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSS 59 GGGGGGS GSGGG GGS G S GG GGS S S+ Sbjct: 592 GGGGGGSSGGRGSGGGSSGGSIG------GRGSSSGGVKSSGGSSSVKFVST 637 Score = 35.4 bits (80), Expect = 0.19 Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 1/46 (2%) Query: 14 SGPSAGSGGGGFGGSAAVAAATASGG-KSGGGSCGGGGSYSASSSS 58 SG + GGGG GS + + G SGGG GG GSY + SS Sbjct: 513 SGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSS 558 Score = 32.0 bits (71), Expect = 2.1 Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 2/53 (3%) Query: 17 SAGSGGGGFGGSAAVAAAT--ASGGKSGGGSCGGGGSYSASSSSSAAAAAGAA 67 S G GG GG ++ + GG G G GGGG S S S+ + G + Sbjct: 513 SGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGS 565 Score = 31.2 bits (69), Expect = 3.6 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 7/53 (13%) Query: 15 GPSAGSGGGGFGGSAAVAAATASGGKSGGG-SCGGGGSYSASSSSSAAAAAGA 66 G S G GGGG+G + S G GG GGGG S S ++ G+ Sbjct: 515 GGSRGGGGGGYGSGGS------SYGSGGGSYGSGGGGGGGRGSYGSGGSSYGS 561 Score = 30.0 bits (66), Expect = 8.1 Identities = 15/39 (38%), Positives = 22/39 (56%) Query: 28 SAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGA 66 + +V+ +T+ SGGGS GGGG S SS + G+ Sbjct: 500 NVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGS 538 >gi|109452587 family with sequence similarity 98, member B isoform 1 [Homo sapiens] Length = 433 Score = 49.7 bits (117), Expect = 1e-05 Identities = 23/43 (53%), Positives = 23/43 (53%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGG 50 GGGGGG G G GGGG GG GG GGG GGGG Sbjct: 339 GGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGG 381 Score = 45.4 bits (106), Expect = 2e-04 Identities = 21/46 (45%), Positives = 22/46 (47%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSY 52 GGGGGGG G GGGG+GG GG G G G G Y Sbjct: 348 GGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDY 393 Score = 45.4 bits (106), Expect = 2e-04 Identities = 22/59 (37%), Positives = 23/59 (38%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 GGGGGGG G G G GGF G GG+ G G G G Y G Sbjct: 369 GGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGG 427 Score = 44.3 bits (103), Expect = 4e-04 Identities = 22/44 (50%), Positives = 23/44 (52%), Gaps = 4/44 (9%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGG 50 GGGGGG G G G GG+GG GG GGG GGGG Sbjct: 341 GGGGGGRGGGGGGGGRGGWGG----GGGGWGGGGGGGGGWGGGG 380 Score = 43.5 bits (101), Expect = 7e-04 Identities = 22/47 (46%), Positives = 22/47 (46%) Query: 4 QKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGG 50 QK GGGG G G GGGG GG GG GG GGGG Sbjct: 326 QKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGG 372 Score = 43.1 bits (100), Expect = 0.001 Identities = 21/44 (47%), Positives = 21/44 (47%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGG 50 GGGG GG G G GG G GG GG GGG G GG Sbjct: 343 GGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGG 386 Score = 42.7 bits (99), Expect = 0.001 Identities = 21/44 (47%), Positives = 22/44 (50%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGG 50 GGG GGG G G GGGG GG GG+ G G GG G Sbjct: 363 GGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYG 406 Score = 42.0 bits (97), Expect = 0.002 Identities = 20/46 (43%), Positives = 21/46 (45%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSY 52 GGGGG G G G GG GG GG GGG GG G + Sbjct: 342 GGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGF 387 Score = 42.0 bits (97), Expect = 0.002 Identities = 21/43 (48%), Positives = 21/43 (48%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGG 50 GGGGGG G G GGGG GG GG G G GG G Sbjct: 367 GGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRG 409 Score = 41.6 bits (96), Expect = 0.003 Identities = 23/51 (45%), Positives = 23/51 (45%), Gaps = 5/51 (9%) Query: 7 GGGGGGGSGPSAGSGG-----GGFGGSAAVAAATASGGKSGGGSCGGGGSY 52 GGGGGGG G G GG GG GG GG G G GG G Y Sbjct: 349 GGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGY 399 Score = 41.6 bits (96), Expect = 0.003 Identities = 20/46 (43%), Positives = 20/46 (43%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSY 52 GGGGGG G G GG G GG G G G GG G Y Sbjct: 360 GGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGY 405 Score = 39.7 bits (91), Expect = 0.010 Identities = 24/66 (36%), Positives = 26/66 (39%), Gaps = 20/66 (30%) Query: 7 GGGGGGGSGPSAGSGGGG----------FGGSAAVAAATASGGK----------SGGGSC 46 G GGGGG G G GGGG +GG GG+ GGG Sbjct: 365 GWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGG 424 Query: 47 GGGGSY 52 GGGG Y Sbjct: 425 GGGGGY 430 Score = 31.2 bits (69), Expect = 3.6 Identities = 13/20 (65%), Positives = 15/20 (75%), Gaps = 3/20 (15%) Query: 6 HGGGGGGGSGPSAGSGGGGF 25 +GGGGGGG G G GGGG+ Sbjct: 414 YGGGGGGGGG---GGGGGGY 430 >gi|12707580 paired-like homeobox 2b [Homo sapiens] Length = 314 Score = 49.3 bits (116), Expect = 1e-05 Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 1/66 (1%) Query: 3 PQKHGGGGGGGSG-PSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAA 61 P GG G + PS G+ GGG GG + A A+G GG G GG+ +A+++++AA Sbjct: 192 PDSTGGPGPNPNPTPSCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAA 251 Query: 62 AAAGAA 67 AAA AA Sbjct: 252 AAAAAA 257 Score = 38.5 bits (88), Expect = 0.023 Identities = 18/44 (40%), Positives = 21/44 (47%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGG 50 G G GG G G GG +AA AAA A+ + GG GG Sbjct: 225 GAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGG 268 Score = 38.1 bits (87), Expect = 0.030 Identities = 23/54 (42%), Positives = 27/54 (50%), Gaps = 11/54 (20%) Query: 7 GGGGGGGSGPS-------AGSGGGGF----GGSAAVAAATASGGKSGGGSCGGG 49 G GGGG GPS AG GG G GG+AA AAA A+ + + GG Sbjct: 209 GANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGG 262 >gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] Length = 532 Score = 48.9 bits (115), Expect = 2e-05 Identities = 24/52 (46%), Positives = 25/52 (48%) Query: 6 HGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSS 57 H GGG G G GSGGG G A GG SGGGS GG SS+ Sbjct: 475 HRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSN 526 Score = 46.2 bits (108), Expect = 1e-04 Identities = 22/50 (44%), Positives = 25/50 (50%) Query: 9 GGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSS 58 GGG GSG + G GGG G A GG S GG G G +S SS+ Sbjct: 477 GGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSN 526 Score = 43.5 bits (101), Expect = 7e-04 Identities = 23/50 (46%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Query: 11 GGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSA 60 GGGSG S G+GGG GGS + +GG GG S GG G+ S S+ Sbjct: 477 GGGSG-SGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSS 525 Score = 34.7 bits (78), Expect = 0.33 Identities = 16/50 (32%), Positives = 21/50 (42%) Query: 16 PSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 P+A + +AA +A GG SG G GGG + S A G Sbjct: 455 PAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGG 504 Score = 33.5 bits (75), Expect = 0.73 Identities = 17/52 (32%), Positives = 22/52 (42%) Query: 14 SGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAG 65 S +A + +AAV+A GG GG+ GG G S S A G Sbjct: 454 SPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGG 505 Score = 32.0 bits (71), Expect = 2.1 Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 7/50 (14%) Query: 17 SAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGA 66 SA GGG G A GG SGGGS GGG A ++ G+ Sbjct: 472 SAVHRGGGSGSGGA-------GGGSGGGSGSGGGGGGAGGGGGGSSGGGS 514 Score = 30.8 bits (68), Expect = 4.7 Identities = 15/39 (38%), Positives = 19/39 (48%) Query: 28 SAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGA 66 +AA AAA ++ + GG GG G S S S GA Sbjct: 464 AAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGA 502 >gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens] Length = 1215 Score = 48.9 bits (115), Expect = 2e-05 Identities = 21/44 (47%), Positives = 26/44 (59%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGS 51 GGGGGG G S G GG G G S+A +GG + +CGGG + Sbjct: 19 GGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAA 62 Score = 47.4 bits (111), Expect = 5e-05 Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 4/65 (6%) Query: 7 GGGGGGG----SGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAA 62 GGG GG SG G+GGGG GGS++ AAT++ S + + +A+++ + A Sbjct: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189 Query: 63 AAGAA 67 + GAA Sbjct: 190 SVGAA 194 Score = 41.2 bits (95), Expect = 0.004 Identities = 19/60 (31%), Positives = 29/60 (48%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAA 67 G GG G + G GGGG S A +A A+ + + + +A + + + AAGAA Sbjct: 138 GDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAA 197 Score = 33.5 bits (75), Expect = 0.73 Identities = 35/116 (30%), Positives = 45/116 (38%), Gaps = 23/116 (19%) Query: 22 GGGFGGSAAVAAATASGGKSGGGSCGGGGSYS--------ASSSSSAAAAAGAAVLPVKK 73 GGG GG GG SGGG G GG YS A +++AAA G A L + Sbjct: 19 GGGGGG----------GGSSGGGG-GAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLP 67 Query: 74 PKMEHVQADHELFLQAFEKPTQIYRFLRTRNLI--APIFLHRTLTYMSHRNSRTNI 127 P Q+ L A + + + F R P + R + Y S S I Sbjct: 68 P--GKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREI 121 Score = 33.5 bits (75), Expect = 0.73 Identities = 25/67 (37%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGA 66 GGGGG G G S+ G G A AAA A GG + G G + S S AA A Sbjct: 29 GGGGGAGGGYSSACRPGPRAGGA--AAAAACGGGAALGLLPPGKTQSPESLLDIAARRVA 86 Query: 67 AVLPVKK 73 P ++ Sbjct: 87 EKWPFQR 93 >gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sapiens] Length = 378 Score = 48.1 bits (113), Expect = 3e-05 Identities = 22/45 (48%), Positives = 27/45 (60%), Gaps = 1/45 (2%) Query: 9 GGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYS 53 GG GG GP G+ GGG+GG GG GGG+ GGGG+Y+ Sbjct: 287 GGYGGGGPGYGNQGGGYGGGGGYDGYN-EGGNFGGGNYGGGGNYN 330 Score = 39.7 bits (91), Expect = 0.010 Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 8/55 (14%) Query: 8 GGGGGGSGPSAGSGG-GGFGGSAAVAAATASGGKSG-------GGSCGGGGSYSA 54 GGGGG G GG GG+GG + + GG G GG+ GGG YS+ Sbjct: 231 GGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSS 285 Score = 37.4 bits (85), Expect = 0.051 Identities = 22/49 (44%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Query: 6 HGGGGGGGSGPSAGSGGG--GFGGSAAVAAATASGGKSGGGSCGGGGSY 52 +GGGGGG G G GG GFGG G S GG GGG Y Sbjct: 249 YGGGGGGSRGSYGGGDGGYNGFGGDGGNYGG-GPGYSSRGGYGGGGPGY 296 Score = 37.4 bits (85), Expect = 0.051 Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 15/60 (25%) Query: 8 GGGGGGSGPSAGSG----------GGGFGGSAAVAAATASGG-----KSGGGSCGGGGSY 52 GGGGGGS S G G GG +GG ++ GG + GG GGGG Y Sbjct: 250 GGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGY 309 Score = 37.0 bits (84), Expect = 0.066 Identities = 24/56 (42%), Positives = 27/56 (48%), Gaps = 6/56 (10%) Query: 4 QKHGGGGGG---GSGPSAGSGGGGFGGSAAVAAATASGGKSGG--GSCGGG-GSYS 53 Q+ GGG G G G + G GGG FG GG GG GS GGG G Y+ Sbjct: 213 QRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYN 268 Score = 36.6 bits (83), Expect = 0.086 Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 10/61 (16%) Query: 7 GGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGA 66 GGG GGG G + GG FGG G GGG+ G+YS S+ G Sbjct: 300 GGGYGGGGGYDGYNEGGNFGG----------GNYGGGGNYNDFGNYSGQQQSNYGPMKGG 349 Query: 67 A 67 + Sbjct: 350 S 350 >gi|13775236 scratch [Homo sapiens] Length = 348 Score = 48.1 bits (113), Expect = 3e-05 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 7/84 (8%) Query: 2 APQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAA 61 AP GGGGG G S GSG GG GG+ A A A ++G G+ G GG ++ Sbjct: 144 APDGDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEA---RAGPGAAGAGGRHACGECGKTY 200 Query: 62 AAAGAAVLPVKKPKMEHVQADHEL 85 A + + + K H D +L Sbjct: 201 ATSS----NLSRHKQTHRSLDSQL 220 Score = 31.2 bits (69), Expect = 3.6 Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 13/69 (18%) Query: 4 QKHGGGGGGGSGPSAGS-----GGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSS 58 ++ G + PS S G G GG A GG+S G GG G A + + Sbjct: 125 RRKASNAGSAAAPSTASAAAPDGDAGGGGGA--------GGRSLGSGPGGRGGTRAGAGT 176 Query: 59 SAAAAAGAA 67 A A GAA Sbjct: 177 EARAGPGAA 185 >gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens] Length = 305 Score = 47.8 bits (112), Expect = 4e-05 Identities = 28/65 (43%), Positives = 34/65 (52%), Gaps = 12/65 (18%) Query: 6 HGGGGGGGSGPSAGSGGG----------GFGGSAAVAAATASGG--KSGGGSCGGGGSYS 53 +GGGGGGG G GGG GFGG + + +S G KSGGG GGG S+ Sbjct: 223 YGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWG 282 Query: 54 ASSSS 58 S+S Sbjct: 283 GRSNS 287 Score = 44.3 bits (103), Expect = 4e-04 Identities = 23/61 (37%), Positives = 27/61 (44%) Query: 5 KHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAA 64 K GGGG G G GGGG+ ++ GG G GG GSYS SS + Sbjct: 211 KGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKS 270 Query: 65 G 65 G Sbjct: 271 G 271 Score = 41.2 bits (95), Expect = 0.004 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 5/67 (7%) Query: 6 HGGGGGGGSGPS-AGSGGGGFGGSAAVAAATASGG----KSGGGSCGGGGSYSASSSSSA 60 + GGGGGGS S G GG G GG + GG GG GGGG Y+A Sbjct: 180 YSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGG 239 Query: 61 AAAAGAA 67 ++ G + Sbjct: 240 GSSYGGS 246 Score = 37.0 bits (84), Expect = 0.066 Identities = 20/38 (52%), Positives = 22/38 (57%), Gaps = 11/38 (28%) Query: 3 PQKHGGGGGGG---------SGPSAG--SGGGGFGGSA 29 P K GGGGGGG SGP G GGGG+GGS+ Sbjct: 267 PMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYGGSS 304 >gi|34452713 Ca2+-dependent secretion activator isoform 2 [Homo sapiens] Length = 1314 Score = 47.8 bits (112), Expect = 4e-05 Identities = 41/130 (31%), Positives = 60/130 (46%), Gaps = 31/130 (23%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGG---GSCGGGGSYSASSSSSAAAAA 64 G GGGG+G AG G GG GGS A +SGG +GG S GGG S+ S S Sbjct: 47 GLGGGGAGAGAGVGAGGGGGSGA-----SSGGGAGGLQPSSRAGGGRPSSPSPS------ 95 Query: 65 GAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSR 124 V +K ++E +Q + E +K Q+Y +F+ R + Y + Sbjct: 96 --VVSEKEKEELERLQKEEE----ERKKRLQLY-----------VFVMRCIAYPFNAKQP 138 Query: 125 TNIKRKTFKV 134 T++ R+ K+ Sbjct: 139 TDMARRQQKI 148 >gi|34452715 Ca2+-dependent secretion activator isoform 1 [Homo sapiens] Length = 1353 Score = 47.8 bits (112), Expect = 4e-05 Identities = 41/130 (31%), Positives = 60/130 (46%), Gaps = 31/130 (23%) Query: 8 GGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGG---GSCGGGGSYSASSSSSAAAAA 64 G GGGG+G AG G GG GGS A +SGG +GG S GGG S+ S S Sbjct: 47 GLGGGGAGAGAGVGAGGGGGSGA-----SSGGGAGGLQPSSRAGGGRPSSPSPS------ 95 Query: 65 GAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSR 124 V +K ++E +Q + E +K Q+Y +F+ R + Y + Sbjct: 96 --VVSEKEKEELERLQKEEE----ERKKRLQLY-----------VFVMRCIAYPFNAKQP 138 Query: 125 TNIKRKTFKV 134 T++ R+ K+ Sbjct: 139 TDMARRQQKI 148 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.130 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,868,444 Number of Sequences: 37866 Number of extensions: 1493802 Number of successful extensions: 25296 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 418 Number of HSP's successfully gapped in prelim test: 186 Number of HSP's that attempted gapping in prelim test: 10468 Number of HSP's gapped (non-prelim): 7223 length of query: 739 length of database: 18,247,518 effective HSP length: 110 effective length of query: 629 effective length of database: 14,082,258 effective search space: 8857740282 effective search space used: 8857740282 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.