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Search of human proteins with 197276676
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197276676 cyclin J isoform 3 [Homo sapiens]
(371 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197276676 cyclin J isoform 3 [Homo sapiens] 760 0.0
gi|40254889 cyclin J isoform 2 [Homo sapiens] 756 0.0
gi|197276674 cyclin J isoform 1 [Homo sapiens] 751 0.0
gi|94680985 cyclin J-like [Homo sapiens] 265 5e-71
gi|4502613 cyclin A [Homo sapiens] 67 3e-11
gi|161377472 cyclin A1 isoform c [Homo sapiens] 65 7e-11
gi|161377470 cyclin A1 isoform c [Homo sapiens] 65 7e-11
gi|161377468 cyclin A1 isoform b [Homo sapiens] 65 7e-11
gi|4502611 cyclin A1 isoform a [Homo sapiens] 65 7e-11
gi|5802992 cyclin I [Homo sapiens] 54 2e-07
gi|4757930 cyclin B2 [Homo sapiens] 50 3e-06
gi|16950655 cyclin D1 [Homo sapiens] 49 7e-06
gi|40805832 cyclin G1 [Homo sapiens] 49 7e-06
gi|4757934 cyclin G1 [Homo sapiens] 49 7e-06
gi|153791755 cyclin domain containing [Homo sapiens] 47 3e-05
gi|17318565 cyclin E2 [Homo sapiens] 47 4e-05
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 44 2e-04
gi|14327896 cyclin B1 [Homo sapiens] 44 2e-04
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 43 5e-04
gi|89886237 cyclin I family, member 2 [Homo sapiens] 43 5e-04
gi|4502617 cyclin D2 [Homo sapiens] 41 0.002
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 40 0.003
gi|118572588 cyclin F [Homo sapiens] 40 0.004
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 38 0.013
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 38 0.017
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 38 0.017
gi|4757936 cyclin G2 [Homo sapiens] 38 0.017
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 36 0.049
gi|187608312 cyclin N-terminal domain containing 1 [Homo sapiens] 36 0.063
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 33 0.54
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 760 bits (1963), Expect = 0.0
Identities = 371/371 (100%), Positives = 371/371 (100%)
Query: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA
Sbjct: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
Query: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL
Sbjct: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM
Sbjct: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
Query: 181 AKYADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDND 240
AKYADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDND
Sbjct: 181 AKYADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDND 240
Query: 241 VKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQYRHPTSEQPSCQ 300
VKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQYRHPTSEQPSCQ
Sbjct: 241 VKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQYRHPTSEQPSCQ 300
Query: 301 QIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQINE 360
QIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQINE
Sbjct: 301 QIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQINE 360
Query: 361 HYPCITPCFER 371
HYPCITPCFER
Sbjct: 361 HYPCITPCFER 371
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 756 bits (1951), Expect = 0.0
Identities = 371/372 (99%), Positives = 371/372 (99%), Gaps = 1/372 (0%)
Query: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA
Sbjct: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
Query: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL
Sbjct: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM
Sbjct: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
Query: 181 AKYADYFLEVSLQ-AAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDN 239
AKYADYFLEVSLQ AAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDN
Sbjct: 181 AKYADYFLEVSLQVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDN 240
Query: 240 DVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQYRHPTSEQPSC 299
DVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQYRHPTSEQPSC
Sbjct: 241 DVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQYRHPTSEQPSC 300
Query: 300 QQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQIN 359
QQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQIN
Sbjct: 301 QQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQIN 360
Query: 360 EHYPCITPCFER 371
EHYPCITPCFER
Sbjct: 361 EHYPCITPCFER 372
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 751 bits (1940), Expect = 0.0
Identities = 371/383 (96%), Positives = 371/383 (96%), Gaps = 12/383 (3%)
Query: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA
Sbjct: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
Query: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL
Sbjct: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM
Sbjct: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
Query: 181 AKYADYFLEVSLQ------------AAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 228
AKYADYFLEVSLQ AAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ
Sbjct: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 240
Query: 229 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 288
CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ
Sbjct: 241 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 300
Query: 289 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 348
YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL
Sbjct: 301 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 360
Query: 349 SVSYNRSYQINEHYPCITPCFER 371
SVSYNRSYQINEHYPCITPCFER
Sbjct: 361 SVSYNRSYQINEHYPCITPCFER 383
>gi|94680985 cyclin J-like [Homo sapiens]
Length = 435
Score = 265 bits (677), Expect = 5e-71
Identities = 168/442 (38%), Positives = 232/442 (52%), Gaps = 81/442 (18%)
Query: 3 LEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARH 62
++ WW G++A+D+H LR KELKLP+++ SP L RR+F D++ ++S+ LCP+ARH
Sbjct: 2 MDEPWWEGRVASDVHCTLREKELKLPTFRAHSPLLKSRRFFVDILTLLSSHCQLCPAARH 61
Query: 63 LAVYLLDLFMDRYDISI-QQLHLVALSCLLLAS--------------------------- 94
LAVYLLD FMDRY+++ +QL+ VA+SCLLLA+
Sbjct: 62 LAVYLLDHFMDRYNVTTSKQLYTVAVSCLLLANGVSLLSPRLKCSGMISAHCNLHLPGSS 121
Query: 95 ---------------------KFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELL 133
KFE++ED VPKLEQ+NS +++ N LTK+ LL ELL
Sbjct: 122 NSPASAPHPPPTPPQVAETTGKFEDREDHVPKLEQINSTRILSSQNFTLTKKELLSTELL 181
Query: 134 LLETFQWNLCLPTAAHFIEYYLSEAVHETDLH-DGWPMICLEKTKLYMAKYADYFLEVSL 192
LLE F WNLCLPT AHF++YYL +V + D H WP C KTK + +YA YFLEV+L
Sbjct: 182 LLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKECLKEYAHYFLEVTL 241
Query: 193 Q------------AAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDND 240
Q AAACV +SRI L+LSP W L R+++YS + L CIE LL+ +DN
Sbjct: 242 QDHIFYKFQPSVVAAACVGASRICLQLSPYWTRDLQRISSYSLEHLSTCIEILLVVYDNV 301
Query: 241 VKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQY--LHQTHQTSLQYRHPTSEQPS 298
+K+A + QA L++ V FQ P Y L Q T Q++ P +
Sbjct: 302 LKDAVAVKSQA------LAMVPGTPPTPTQVLFQPPAYPALGQPATTLAQFQTPVQDLCL 355
Query: 299 CQQIVSTTHTSSYTLQ-TCPAGFQTSVQGLGHMQ-------TGVGMSLAIPVEVKPCLSV 350
+ H S L + + T Q L + + M +AI E + CL+
Sbjct: 356 AYRDSLQAHRSGSLLSGSTGSSLHTPYQPLQPLDMCPVPVPASLSMHMAIAAEPRHCLAT 415
Query: 351 SYNRSYQINEH-YPCITPCFER 371
+Y SY H +P T CF+R
Sbjct: 416 TYGSSYFSGSHMFP--TGCFDR 435
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 66.6 bits (161), Expect = 3e-11
Identities = 69/251 (27%), Positives = 103/251 (41%), Gaps = 27/251 (10%)
Query: 15 DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69
DIH LR E+K Y + P + S+R D + V + L HLAV +D
Sbjct: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
Query: 70 LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129
F+ + +L LV + +LLASKFEE P++ + + T TK+ +L
Sbjct: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293
Query: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLE 189
ME L+L+ ++L PT F+ Y + M E + + Y Y
Sbjct: 294 MEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPS 353
Query: 190 VSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEANKQRG 249
V AA +A + +WP L R T Y+ + L C L+ H +K
Sbjct: 354 VIAGAAFHLALYTV---TGQSWPESLIRKTGYTLESLKPC---LMDLHQTYLK------- 400
Query: 250 QAGPQSAQLSV 260
PQ AQ S+
Sbjct: 401 --APQHAQQSI 409
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 65.5 bits (158), Expect = 7e-11
Identities = 63/231 (27%), Positives = 101/231 (43%), Gaps = 22/231 (9%)
Query: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
+ A +I+Q LR E++ Y + P ++ +R D + V + L +LAV
Sbjct: 166 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 225
Query: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
LD F+ + +L LV + +LLASK+EE P++++ + T TK+
Sbjct: 226 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 278
Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSE---AVHETDLHDGWPMICLEKTKLYMAK 182
LL ME LLL+ ++L +PT F+ YL V +L E + L
Sbjct: 279 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL----AKYVAELSLLEADP 334
Query: 183 YADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 233
+ Y + AA C+A+ + WP L T YS +V C+ L
Sbjct: 335 FLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCLSEL 382
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 65.5 bits (158), Expect = 7e-11
Identities = 63/231 (27%), Positives = 101/231 (43%), Gaps = 22/231 (9%)
Query: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
+ A +I+Q LR E++ Y + P ++ +R D + V + L +LAV
Sbjct: 166 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 225
Query: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
LD F+ + +L LV + +LLASK+EE P++++ + T TK+
Sbjct: 226 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 278
Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSE---AVHETDLHDGWPMICLEKTKLYMAK 182
LL ME LLL+ ++L +PT F+ YL V +L E + L
Sbjct: 279 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL----AKYVAELSLLEADP 334
Query: 183 YADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 233
+ Y + AA C+A+ + WP L T YS +V C+ L
Sbjct: 335 FLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCLSEL 382
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 65.5 bits (158), Expect = 7e-11
Identities = 63/231 (27%), Positives = 101/231 (43%), Gaps = 22/231 (9%)
Query: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
+ A +I+Q LR E++ Y + P ++ +R D + V + L +LAV
Sbjct: 209 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 268
Query: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
LD F+ + +L LV + +LLASK+EE P++++ + T TK+
Sbjct: 269 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 321
Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSE---AVHETDLHDGWPMICLEKTKLYMAK 182
LL ME LLL+ ++L +PT F+ YL V +L E + L
Sbjct: 322 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL----AKYVAELSLLEADP 377
Query: 183 YADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 233
+ Y + AA C+A+ + WP L T YS +V C+ L
Sbjct: 378 FLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCLSEL 425
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 65.5 bits (158), Expect = 7e-11
Identities = 63/231 (27%), Positives = 101/231 (43%), Gaps = 22/231 (9%)
Query: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
+ A +I+Q LR E++ Y + P ++ +R D + V + L +LAV
Sbjct: 210 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 269
Query: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
LD F+ + +L LV + +LLASK+EE P++++ + T TK+
Sbjct: 270 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 322
Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSE---AVHETDLHDGWPMICLEKTKLYMAK 182
LL ME LLL+ ++L +PT F+ YL V +L E + L
Sbjct: 323 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL----AKYVAELSLLEADP 378
Query: 183 YADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 233
+ Y + AA C+A+ + WP L T YS +V C+ L
Sbjct: 379 FLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCLSEL 426
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 54.3 bits (129), Expect = 2e-07
Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 19/175 (10%)
Query: 26 KLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLV 85
K+PS + SP S R +A + +F L P LA LLD F+ + L +
Sbjct: 33 KMPSNQNVSP--SQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90
Query: 86 ALSCLLLASKFEEKEDSVPKLEQL---NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
A+SC LA+K E+++ +P L+ L + GC + +L ME ++L+ W+L
Sbjct: 91 AISCFFLAAKTVEEDERIPVLKVLARDSFCGC--------SSSEILRMERIILDKLNWDL 142
Query: 143 CLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQAAAC 197
T F+ + + AV P + KL +++ + L AC
Sbjct: 143 HTATPLDFLHIFHAIAVSTR------PQLLFSLPKLSPSQHLAVLTKQLLHCMAC 191
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 50.1 bits (118), Expect = 3e-06
Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 15/153 (9%)
Query: 7 WWRGQLAAD----IHQALRYKELKL---PSY-KGQSPQLSLRRYFADLIAIVSNRFTLCP 58
W QL +D I+Q LR E+ P + G+ +R D + V ++F L
Sbjct: 125 WENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQ 184
Query: 59 SARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNM 118
++ V ++D F+ +S ++L LV ++ LLLASK+EE P +E +
Sbjct: 185 ETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFS--PNIEDFVYI-----T 237
Query: 119 NLVLTKQNLLHMELLLLETFQWNLCLPTAAHFI 151
+ T + ME L+L+ ++ L P HF+
Sbjct: 238 DNAYTSSQIREMETLILKELKFELGRPLPLHFL 270
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 48.9 bits (115), Expect = 7e-06
Identities = 33/96 (34%), Positives = 54/96 (56%), Gaps = 9/96 (9%)
Query: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVP-KLEQLNSLGCMTNMNLV 121
LA+ LD F+ + +L L+ +C+ +ASK +E ++P E+L C+ N +
Sbjct: 80 LAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKL----CIYTDNSI 132
Query: 122 LTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSE 157
++ LL MELLL+ +WNL T FIE++LS+
Sbjct: 133 RPEE-LLQMELLLVNKLKWNLAAMTPHDFIEHFLSK 167
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 48.9 bits (115), Expect = 7e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
LAV LLD F+ + + + L V LSC LA K E+E +VP L +
Sbjct: 75 LAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRIS-----QYRF 129
Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLS 156
T +L+ ME ++LE W + TA F++ Y S
Sbjct: 130 TVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYS 163
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 48.9 bits (115), Expect = 7e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
LAV LLD F+ + + + L V LSC LA K E+E +VP L +
Sbjct: 75 LAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRIS-----QYRF 129
Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLS 156
T +L+ ME ++LE W + TA F++ Y S
Sbjct: 130 TVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYS 163
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 47.0 bits (110), Expect = 3e-05
Identities = 44/170 (25%), Positives = 79/170 (46%), Gaps = 11/170 (6%)
Query: 50 VSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQL 109
V +F L + L V LD F+ ++ L+ ++ LL+A K + E P+++QL
Sbjct: 143 VHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACK--QVEVHPPRVKQL 200
Query: 110 NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVH--ETDLHDG 167
+L C ++Q L ++E ++L + L PT + F+E++ V + + +
Sbjct: 201 LALCCGA-----FSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEA 255
Query: 168 WPMICLEK--TKLYMAKYADYFLEVSLQAAACVASSRIILRLSPTWPTRL 215
L + +L +A YA SL A C+A + +LR+S RL
Sbjct: 256 LEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRL 305
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 46.6 bits (109), Expect = 4e-05
Identities = 33/118 (27%), Positives = 59/118 (50%), Gaps = 8/118 (6%)
Query: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFM-DRYDISIQQLHLVALSCLLLASKFE 97
+R D + V +TL +LA D FM + DI+ L L+ ++ L +ASK E
Sbjct: 141 MRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLE 200
Query: 98 EKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYL 155
E PKL++ + + +++++L MEL++L+ +W LC T ++ +L
Sbjct: 201 EIY--APKLQEFAYV-----TDGACSEEDILRMELIILKALKWELCPVTIISWLNLFL 251
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 44.3 bits (103), Expect = 2e-04
Identities = 32/136 (23%), Positives = 65/136 (47%), Gaps = 9/136 (6%)
Query: 21 RYKELKLPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDIS 78
R ++ L Y + +++ +R D + V F + +LAV L+DL++ +
Sbjct: 1140 REEQFILTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCK 1199
Query: 79 IQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETF 138
+L L+ + ++A+KFEE P+++ + C N + +L ME+ +L
Sbjct: 1200 KDKLQLLGATAFMIAAKFEEHNS--PRVDDFVYI-CDDNYQ----RSEVLSMEINILNVL 1252
Query: 139 QWNLCLPTAAHFIEYY 154
+ ++ +P A HF+ Y
Sbjct: 1253 KCDINIPIAYHFLRRY 1268
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 43.9 bits (102), Expect = 2e-04
Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 11/141 (7%)
Query: 15 DIHQALRYKELKL---PSYK-GQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDL 70
DI+ LR E + P Y G+ ++R D + V +F L ++ V ++D
Sbjct: 173 DIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDR 232
Query: 71 FMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHM 130
FM + + L LV ++ + +ASK+EE ++ +T+ TK + M
Sbjct: 233 FMQNNCVPKKMLQLVGVTAMFIASKYEEMYP-----PEIGDFAFVTDN--TYTKHQIRQM 285
Query: 131 ELLLLETFQWNLCLPTAAHFI 151
E+ +L + L P HF+
Sbjct: 286 EMKILRALNFGLGRPLPLHFL 306
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 42.7 bits (99), Expect = 5e-04
Identities = 35/132 (26%), Positives = 62/132 (46%), Gaps = 15/132 (11%)
Query: 28 PSYKGQSPQ-----LSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQL 82
PS +SP L R F DL + F + +LAV L+DL++ + +L
Sbjct: 43 PSSLQESPSSLQGALKKRSAFEDLTNV---SFEMTHETLYLAVKLVDLYLMKAVCKKDKL 99
Query: 83 HLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
L+ + ++A+KFEE P+++ + C N + +L ME+ +L + ++
Sbjct: 100 QLLGATAFMIAAKFEEHNS--PRVDDFVYI-CDDNYQ----RSEVLSMEINILNVLKCDI 152
Query: 143 CLPTAAHFIEYY 154
+P A HF+ Y
Sbjct: 153 NIPIAYHFLRRY 164
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 42.7 bits (99), Expect = 5e-04
Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 8/128 (6%)
Query: 30 YKGQSPQLSLRRYFADLIAIV---SNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVA 86
++G PQ + F +++ + N F S +LA+ + + + + LH
Sbjct: 137 WRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCAT 196
Query: 87 LSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPT 146
++ L LA+K E+E+ +P+++ + + LL MEL +L+ W+L + T
Sbjct: 197 ITSLRLAAKVNEEEEFIPQVKDFTK-----HYGSDYSPNELLRMELAILDRLHWDLYIGT 251
Query: 147 AAHFIEYY 154
F+ +
Sbjct: 252 PLDFLTIF 259
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 7/93 (7%)
Query: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
LA+ LD F+ L L+ C+ LASK KE S E+L C+ N +
Sbjct: 79 LAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKL--KETSPLTAEKL----CIYTDNSI- 131
Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYL 155
Q LL EL++L +WNL T FIE+ L
Sbjct: 132 KPQELLEWELVVLGKLKWNLAAVTPHDFIEHIL 164
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 40.0 bits (92), Expect = 0.003
Identities = 57/223 (25%), Positives = 93/223 (41%), Gaps = 33/223 (14%)
Query: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
LA+ LD ++ QL L+ C+LLASK +E + +E+L C+ + V
Sbjct: 80 LAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVS 133
Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAK 182
+Q L E+L+L +W+L A F+ + L H L + + + ++A
Sbjct: 134 PRQ-LRDWEVLVLGKLKWDLAAVIAHDFLAFIL----HRLSLPRDRQALVKKHAQTFLAL 188
Query: 183 YA-DYFLEV---------SLQAA-----ACVASSRIILRLSPTWPTRLHRLTAYSWDFLV 227
A DY + S+ AA AC S + L L +T D L
Sbjct: 189 CATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTEL-------LAGITGTEVDCLR 241
Query: 228 QCIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 270
C E++ A ++EA++ P++ + S Q SQ S P
Sbjct: 242 ACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 284
>gi|118572588 cyclin F [Homo sapiens]
Length = 786
Score = 39.7 bits (91), Expect = 0.004
Identities = 39/185 (21%), Positives = 83/185 (44%), Gaps = 16/185 (8%)
Query: 47 IAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKL 106
+A + + +LC HL V +D ++ R + +L L+ ++C+++ ++F KE +
Sbjct: 320 VATMKDFTSLC---LHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE-----I 371
Query: 107 EQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHD 166
+ +T+ ++L+ M ++ + + +PT + E L+ E
Sbjct: 372 LTIREAVWLTDN--TYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQH 429
Query: 167 GWPMIC-LEKTKLYMAKYADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDF 225
+C L ++ YA L AAA + +R+ + W T+L LT +S++
Sbjct: 430 LCSFLCELSLLHTSLSAYAPARL-----AAAALLLARLTHGQTQPWTTQLWDLTGFSYED 484
Query: 226 LVQCI 230
L+ C+
Sbjct: 485 LIPCV 489
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 38.1 bits (87), Expect = 0.013
Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 37/219 (16%)
Query: 71 FMDRYDISIQ----QLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQN 126
++DRY + QL L+ C+LLASK +E + +E+L C+ + V +Q
Sbjct: 3 YLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVSPRQ- 55
Query: 127 LLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYA-D 185
L E+L+L +W+L A F+ + L H L + + + ++A A D
Sbjct: 56 LRDWEVLVLGKLKWDLAAVIAHDFLAFIL----HRLSLPRDRQALVKKHAQTFLALCATD 111
Query: 186 YFLEV---------SLQAA-----ACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIE 231
Y + S+ AA AC S + L L +T D L C E
Sbjct: 112 YTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTEL-------LAGITGTEVDCLRACQE 164
Query: 232 RLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 270
++ A ++EA++ P++ + S Q SQ S P
Sbjct: 165 QIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 203
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 37.7 bits (86), Expect = 0.017
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 13/106 (12%)
Query: 66 YLLDLFMDRYDISIQQ-----LHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
YL F DRY + + L L+ +S L +A+K EE PKL Q + +
Sbjct: 167 YLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYP--PKLHQFAYV-----TDG 219
Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHD 166
+ +L MEL++++ +W L T ++ Y+ + + DLH+
Sbjct: 220 ACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYM-QVAYLNDLHE 264
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 37.7 bits (86), Expect = 0.017
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 13/106 (12%)
Query: 66 YLLDLFMDRYDISIQQ-----LHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
YL F DRY + + L L+ +S L +A+K EE PKL Q + +
Sbjct: 152 YLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYP--PKLHQFAYV-----TDG 204
Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHD 166
+ +L MEL++++ +W L T ++ Y+ + + DLH+
Sbjct: 205 ACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYM-QVAYLNDLHE 249
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 37.7 bits (86), Expect = 0.017
Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
LR + + ++N F C LAV +LD F+ + + L + + LLA++ E
Sbjct: 55 LRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVE 114
Query: 99 KEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYY 154
++ ++P + + T ++ ME ++ E + L TA +F+ Y
Sbjct: 115 EDCNIPSTHDVIRIS-----QCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY 165
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 36.2 bits (82), Expect = 0.049
Identities = 23/90 (25%), Positives = 41/90 (45%)
Query: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
+R D + V L +LAV+LLD ++ + + +L L+ ++CL +A K EE
Sbjct: 107 MRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEE 166
Query: 99 KEDSVPKLEQLNSLGCMTNMNLVLTKQNLL 128
P L S + L+ ++ +L
Sbjct: 167 CVLPEPAFLCLLSADSFSRAELLRAERRIL 196
>gi|187608312 cyclin N-terminal domain containing 1 [Homo sapiens]
Length = 330
Score = 35.8 bits (81), Expect = 0.063
Identities = 22/77 (28%), Positives = 40/77 (51%), Gaps = 3/77 (3%)
Query: 79 IQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETF 138
+ + L +SC+ LASK + + + LN L + ++ TK+ LL EL +L++
Sbjct: 117 VNKFTLRLVSCVQLASKLSFRNKIISNITVLNFLQALGYLH---TKEELLESELDVLKSL 173
Query: 139 QWNLCLPTAAHFIEYYL 155
+ + LPT ++E L
Sbjct: 174 NFRINLPTPLAYVETLL 190
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 32.7 bits (73), Expect = 0.54
Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 2/73 (2%)
Query: 246 KQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQYRHPTSEQPSCQQIVST 305
+Q+ Q+ P Q S + QPS+P H Q P T+ Q HP S+ P Q +
Sbjct: 501 QQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ--HPQSQPPYSQPQAQS 558
Query: 306 THTSSYTLQTCPA 318
+ Q P+
Sbjct: 559 PYQQQQPQQPAPS 571
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.133 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,750,703
Number of Sequences: 37866
Number of extensions: 571593
Number of successful extensions: 1566
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1509
Number of HSP's gapped (non-prelim): 50
length of query: 371
length of database: 18,247,518
effective HSP length: 104
effective length of query: 267
effective length of database: 14,309,454
effective search space: 3820624218
effective search space used: 3820624218
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.