Guide to the Human Genome
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Search of human proteins with 196115158

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4
[Homo sapiens]
         (818 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ...  1659   0.0  
gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ...  1645   0.0  
gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ...  1630   0.0  
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ...  1615   0.0  
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [...  1615   0.0  
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       83   1e-15
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       81   4e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    79   2e-14
gi|56549696 E1A binding protein p400 [Homo sapiens]                    79   2e-14
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              75   2e-13
gi|38788274 bromodomain PHD finger transcription factor isoform ...    72   2e-12
gi|146134388 YLP motif containing 1 [Homo sapiens]                     69   2e-11
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]          67   7e-11
gi|119943102 CREB binding protein isoform b [Homo sapiens]             67   9e-11
gi|119943104 CREB binding protein isoform a [Homo sapiens]             67   9e-11
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   66   1e-10
gi|22538413 forkhead box P2 isoform III [Homo sapiens]                 66   1e-10
gi|149999352 forkhead box P2 isoform II [Homo sapiens]                 66   1e-10
gi|38788260 bromodomain PHD finger transcription factor isoform ...    66   1e-10
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       65   2e-10
gi|221139761 zinc finger protein 853 [Homo sapiens]                    64   6e-10
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    64   6e-10
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo...    64   6e-10
gi|110349719 titin isoform N2-A [Homo sapiens]                         64   7e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    63   1e-09
gi|197276594 RNA binding motif protein 20 [Homo sapiens]               63   1e-09
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              63   1e-09
gi|58530845 zyxin [Homo sapiens]                                       62   2e-09
gi|4508047 zyxin [Homo sapiens]                                        62   2e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni...    62   2e-09

>gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4
           [Homo sapiens]
          Length = 818

 Score = 1659 bits (4295), Expect = 0.0
 Identities = 818/818 (100%), Positives = 818/818 (100%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLAT 120
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLAT
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLAT 120

Query: 121 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 180
           PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP
Sbjct: 121 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 180

Query: 181 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 240
           VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS
Sbjct: 181 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 240

Query: 241 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 300
           SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS
Sbjct: 241 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 300

Query: 301 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 360
           QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ
Sbjct: 301 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 360

Query: 361 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGG 420
           PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGG
Sbjct: 361 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGG 420

Query: 421 MEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRA 480
           MEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRA
Sbjct: 421 MEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRA 480

Query: 481 FSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQR 540
           FSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQR
Sbjct: 481 FSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQR 540

Query: 541 LGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAK 600
           LGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAK
Sbjct: 541 LGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAK 600

Query: 601 QSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCF 660
           QSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCF
Sbjct: 601 QSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCF 660

Query: 661 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDFLVPVMGYI 720
           EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDFLVPVMGYI
Sbjct: 661 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDFLVPVMGYI 720

Query: 721 CRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTTRPVSRRCAINARNALTALF 780
           CRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTTRPVSRRCAINARNALTALF
Sbjct: 721 CRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTTRPVSRRCAINARNALTALF 780

Query: 781 TSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 818
           TSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 781 TSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 818


>gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2
           [Homo sapiens]
          Length = 842

 Score = 1645 bits (4260), Expect = 0.0
 Identities = 818/842 (97%), Positives = 818/842 (97%), Gaps = 24/842 (2%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG                        
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 97  NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216
           PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240

Query: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300

Query: 277 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336
           EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360

Query: 337 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 396
           VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP
Sbjct: 361 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 420

Query: 397 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 456
           EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR
Sbjct: 421 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 480

Query: 457 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 516
           EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY
Sbjct: 481 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 540

Query: 517 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 576
           ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC
Sbjct: 541 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 600

Query: 577 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 636
           NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL
Sbjct: 601 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 660

Query: 637 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 696
           KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW
Sbjct: 661 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 720

Query: 697 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 756
           KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN
Sbjct: 721 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 780

Query: 757 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 816
           PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL
Sbjct: 781 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 840

Query: 817 KT 818
           KT
Sbjct: 841 KT 842


>gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3
           [Homo sapiens]
          Length = 837

 Score = 1630 bits (4221), Expect = 0.0
 Identities = 813/842 (96%), Positives = 813/842 (96%), Gaps = 29/842 (3%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG                        
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 97  NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216
           PQKQARTSSSTTPNRK     TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235

Query: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295

Query: 277 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336
           EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355

Query: 337 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 396
           VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP
Sbjct: 356 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 415

Query: 397 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 456
           EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR
Sbjct: 416 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 475

Query: 457 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 516
           EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY
Sbjct: 476 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 535

Query: 517 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 576
           ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC
Sbjct: 536 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 595

Query: 577 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 636
           NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL
Sbjct: 596 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 655

Query: 637 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 696
           KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW
Sbjct: 656 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 715

Query: 697 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 756
           KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN
Sbjct: 716 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 775

Query: 757 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 816
           PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL
Sbjct: 776 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 835

Query: 817 KT 818
           KT
Sbjct: 836 KT 837


>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1
           [Homo sapiens]
          Length = 898

 Score = 1615 bits (4182), Expect = 0.0
 Identities = 818/898 (91%), Positives = 818/898 (91%), Gaps = 80/898 (8%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG                        
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 97  NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216
           PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240

Query: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300

Query: 277 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336
           EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360

Query: 337 VQPQLQQEAEPQ------------------------------------------------ 348
           VQPQLQQEAEPQ                                                
Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420

Query: 349 ----KQVQ----PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 400
               KQVQ    PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480

Query: 401 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 460
           VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540

Query: 461 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 520
           VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600

Query: 521 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 580
           SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660

Query: 581 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 640
           LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720

Query: 641 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 700
           KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780

Query: 701 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 760
           TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840

Query: 761 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 818
           TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898


>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
           [Homo sapiens]
          Length = 898

 Score = 1615 bits (4182), Expect = 0.0
 Identities = 818/898 (91%), Positives = 818/898 (91%), Gaps = 80/898 (8%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG                        
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 97  NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216
           PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240

Query: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300

Query: 277 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336
           EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360

Query: 337 VQPQLQQEAEPQ------------------------------------------------ 348
           VQPQLQQEAEPQ                                                
Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420

Query: 349 ----KQVQ----PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 400
               KQVQ    PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480

Query: 401 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 460
           VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540

Query: 461 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 520
           VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600

Query: 521 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 580
           SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660

Query: 581 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 640
           LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720

Query: 641 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 700
           KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780

Query: 701 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 760
           TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840

Query: 761 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 818
           TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 92/320 (28%), Positives = 132/320 (41%), Gaps = 67/320 (20%)

Query: 5   QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54
           Q QQQ+QQQQQQLQ++       QQQQ QQQQ QQQQ LQ Q  +QQ P   PQ P   A
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285

Query: 55  VSRGL----------PPQQPQQPLLNLQG-------------TNSASLLNGSML------ 85
           + + L          PP QPQQP +                  + A  L G ML      
Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPL 345

Query: 86  ---QRALLLQQ--LQGNLRGYGMASPGLAAPSLTPP--QLATPNLQQFFPQATRQSLLGP 138
              +  +++QQ  +Q  ++    A     A  +  P  Q+ T  L Q       +    P
Sbjct: 346 KFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARF---P 402

Query: 139 PPVGVPMNPSQFNLSGRNPQKQARTS-----SSTTPNRKDSSSQTMPVEDKSDPPEGSEE 193
           P   V   PS     GR P  Q   S     SS +P ++  + Q+MP      PP+ S +
Sbjct: 403 PTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMP-----PPPQPSPQ 457

Query: 194 AAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL 253
             +P      +    P P   +     P+P P+P + S + A+  ++   P+    PG L
Sbjct: 458 PGQPSSQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS----PGPL 509

Query: 254 QVKAQPQARMTVPKQTQTPD 273
                P + M+    +Q  +
Sbjct: 510 NTPVNPSSVMSPAGSSQAEE 529



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 104/408 (25%), Positives = 139/408 (34%), Gaps = 87/408 (21%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
           QQQQQQ QQQQQ   Q QQQQ QQQQ Q QQ    QQ       Q  L          QQ
Sbjct: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ-------QQQ 215

Query: 64  PQQPLLNLQGTNSASL-LNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPN 122
            QQ L+ L   N   +      LQR   LQ  Q   +          A    PP +  P 
Sbjct: 216 QQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPP-IQQPP 274

Query: 123 LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN---PQKQARTSSSTTPNRKDSSSQTM 179
           +QQ  P         PP   +P    Q + +  +   PQ Q    +   P++    SQT 
Sbjct: 275 MQQPQP---------PPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325

Query: 180 PVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLR 239
           P+  ++    G     +P                                    P K +R
Sbjct: 326 PLVSQAQALPGQMLYTQP------------------------------------PLKFVR 349

Query: 240 SSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQ 299
           +      ++PP Q QV+ Q  A  T             A  AQ++      + +  AQ  
Sbjct: 350 A--PMVVQQPPVQPQVQQQQTAVQT-------------AQAAQMVAPGVQMITEALAQGG 394

Query: 300 SQTQPRIPSTDT-----QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQ 354
              + R P T            L +Q   Q S   L +      P   Q+ +  + + P 
Sbjct: 395 MHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLS---SPSPGQQVQTPQSMPPP 451

Query: 355 VHTQAQPSVQPQEHPPAQVSVQP-PEQTHEQPHTQPQVSLLAPEQTPV 401
                QP  QP   P + VS  P P  +   P   PQ     P Q+PV
Sbjct: 452 PQPSPQPG-QPSSQPNSNVSSGPAPSPSSFLPSPSPQ-----PSQSPV 493



 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 57/195 (29%), Positives = 90/195 (46%), Gaps = 11/195 (5%)

Query: 222 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 281
           AP      ++  P  +L+  +   +++   Q Q + Q QA +   +Q Q      +A ++
Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194

Query: 282 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 340
            +  +FQ  V Q Q  Q Q Q Q  +     Q Q ++Q+Q Q       L LQQ+Q Q Q
Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254

Query: 341 LQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 399
            QQ+ + Q  Q QP +    QP +Q  + PP+Q   Q  +Q H   H QP      P+Q 
Sbjct: 255 QQQQQQQQALQAQPPIQ---QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQP 308

Query: 400 PVVVHVCGLEMPPDA 414
           PV  +    ++PP +
Sbjct: 309 PVAQNQPS-QLPPQS 322



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 67/272 (24%), Positives = 100/272 (36%), Gaps = 30/272 (11%)

Query: 128 PQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP 187
           P    QSL G P  G     +   +  R P +      S         +   P+     P
Sbjct: 81  PMNALQSLTGGPAAGA----AGIGMPPRGPGQSLGGMGSL-------GAMGQPMSLSGQP 129

Query: 188 PEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEK 247
           P G+   A   M           P+   + ++    + +  +  +   +     ++  ++
Sbjct: 130 PPGTSGMAPHSMAVVSTAT----PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ 185

Query: 248 EPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIP 307
           +   Q Q  A  Q    V +Q Q   L  +  + Q L +      Q Q Q+Q Q Q    
Sbjct: 186 QQQFQAQQSAMQQQFQAVVQQQQ--QLQQQQQQQQHLIKLHH---QNQQQIQQQQQQLQR 240

Query: 308 STDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ-PQLQQEAEPQKQVQPQV-----HTQ-AQ 360
               Q+Q + Q+Q Q Q   +  +  Q  +Q P +QQ   P  Q  PQ      HTQ  Q
Sbjct: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300

Query: 361 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVS 392
           P  QPQ+ P AQ     P Q   Q  TQP VS
Sbjct: 301 PPPQPQQPPVAQ---NQPSQLPPQSQTQPLVS 329



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 79/365 (21%), Positives = 128/365 (35%), Gaps = 62/365 (16%)

Query: 91  LQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQF 150
           LQ L G   G    + G+  P   P Q +   +          SL G PP G        
Sbjct: 85  LQSLTG---GPAAGAAGIGMPPRGPGQ-SLGGMGSLGAMGQPMSLSGQPPPGT------- 133

Query: 151 NLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPC 210
             SG  P   A  S++T   +       +  + +    +  ++AA  +    + Q     
Sbjct: 134 --SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQA 191

Query: 211 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ 270
            +   +++                   ++  ++  +++   Q  +K   Q +  + +Q Q
Sbjct: 192 QQSAMQQQFQAV---------------VQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQ 236

Query: 271 TPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHL 330
               + + L+ Q       +  Q Q Q Q Q Q  + +     QP +Q   Q Q  P   
Sbjct: 237 QLQRIAQ-LQLQ-------QQQQQQQQQQQQQQQALQAQPPIQQPPMQ---QPQPPPSQA 285

Query: 331 VLQQKQVQPQLQQEAEPQKQVQPQV----------HTQAQPSV-QPQEHPPAQVSVQPP- 378
           + QQ Q     Q    P +  QP V           +Q QP V Q Q  P   +  QPP 
Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPL 345

Query: 379 ---------EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPV 429
                    +Q   QP  Q Q + +   Q   +V   G++M  +A+ A GGM      P 
Sbjct: 346 KFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV-APGVQMITEAL-AQGGMHIRARFPP 403

Query: 430 GTQVS 434
            T VS
Sbjct: 404 TTAVS 408


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 85/291 (29%), Positives = 123/291 (42%), Gaps = 49/291 (16%)

Query: 5   QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54
           Q QQQ+QQQQQQLQ++       QQQQ QQQQ QQQQ LQ Q  +QQ P   PQ P   A
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285

Query: 55  VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGNLRGYG 102
           + + L          PP QPQQP +     N  S L      + L+   Q L G +    
Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342

Query: 103 MASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQAR 162
                + AP +       P +QQ   Q   Q+      V   +  SQ +L          
Sbjct: 343 PPLKFVRAPMVVQQPPVQPQVQQ--QQTAVQTAQAAQMVAPGVQVSQSSLP--------- 391

Query: 163 TSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPA 222
             SS +P ++  + Q+MP      PP+ S +  +P      +    P P   +     P+
Sbjct: 392 MLSSPSPGQQVQTPQSMP-----PPPQPSPQPGQPSSQPNSNVSSGPAP---SPSSFLPS 443

Query: 223 PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPD 273
           P P+P + S + A+  ++   P+    PG L     P + M+    +Q  +
Sbjct: 444 PSPQPSQ-SPVTARTPQNFSVPS----PGPLNTPVNPSSVMSPAGSSQAEE 489



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 85/329 (25%), Positives = 113/329 (34%), Gaps = 42/329 (12%)

Query: 2   FSQQQQQQLQQQQQQLQQ------------------LQQQQLQQQQLQQQQLLQLQQLLQ 43
           F QQQQ  LQQQQQQ QQ                   QQQQLQQQQ QQQ L++L    Q
Sbjct: 169 FQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQ 228

Query: 44  QSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQR-----------ALLLQ 92
           Q   Q    +     L  QQ QQ     Q     +L     +Q+             L Q
Sbjct: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQ 288

Query: 93  QLQGNLRGYGMASP--------GLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVP 144
           QLQ          P            PS  PPQ  T  L         Q L   PP+   
Sbjct: 289 QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFV 348

Query: 145 MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP----PEGSEEAAEPRMD 200
             P         PQ Q + ++  T       +  + V   S P    P   ++   P+  
Sbjct: 349 RAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSM 408

Query: 201 TPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQ 260
            P  Q  P   +  ++     +  P P  +S LP+   + S+ P     P    V +   
Sbjct: 409 PPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGP 468

Query: 261 ARMTV-PKQTQTPDLLPEALEAQVLPRFQ 288
               V P    +P    +A E Q L + +
Sbjct: 469 LNTPVNPSSVMSPAGSSQAEEQQYLDKLK 497



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 93/365 (25%), Positives = 129/365 (35%), Gaps = 47/365 (12%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
           QQQQQQ QQQQQ   Q QQQQ QQQQ Q QQ    QQ       Q  L          QQ
Sbjct: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ-------QQQ 215

Query: 64  PQQPLLNLQGTNSASL-LNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPN 122
            QQ L+ L   N   +      LQR   LQ  Q   +          A    PP +  P 
Sbjct: 216 QQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPP-IQQPP 274

Query: 123 LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN---PQKQARTSSSTTPNRKDSSSQTM 179
           +QQ  P         PP   +P    Q + +  +   PQ Q    +   P++    SQT 
Sbjct: 275 MQQPQP---------PPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325

Query: 180 PVEDKSDPPEGSEEAAEPRMD---TPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAK 236
           P+  ++    G     +P +     P     PP    +  +++  A +         P  
Sbjct: 326 PLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV--QQQQTAVQTAQAAQMVAPGV 383

Query: 237 RLRSSEEPTEKEP-PGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQ 295
           ++  S  P    P PGQ               Q QTP  +P   +    P  QP   Q  
Sbjct: 384 QVSQSSLPMLSSPSPGQ---------------QVQTPQSMPPPPQPSPQPG-QPS-SQPN 426

Query: 296 AQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQV 355
           + V S   P   S      P+  +   T  +P++  +        L     P   + P  
Sbjct: 427 SNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPS---PGPLNTPVNPSSVMSPAG 483

Query: 356 HTQAQ 360
            +QA+
Sbjct: 484 SSQAE 488



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 88/333 (26%), Positives = 135/333 (40%), Gaps = 61/333 (18%)

Query: 222 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 281
           AP      ++  P  +L+  +   +++   Q Q + Q QA +   +Q Q      +A ++
Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194

Query: 282 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 340
            +  +FQ  V Q Q  Q Q Q Q  +     Q Q ++Q+Q Q       L LQQ+Q Q Q
Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254

Query: 341 LQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 399
            QQ+ + Q  Q QP +    QP +Q  + PP+Q   Q  +Q H   H QP      P+Q 
Sbjct: 255 QQQQQQQQALQAQPPIQ---QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQP 308

Query: 400 PVVVHVCGLEMPP---------DAVEAGGGMEKTLP-------------EPVGTQVSMEE 437
           PV  +    ++PP          A    G M  T P              PV  QV  ++
Sbjct: 309 PVAQNQPS-QLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367

Query: 438 IQNESACGLDVGECENRAREM--PGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPS-- 493
              ++A          +A +M  PGV  +  SL +    S   +  +   + P P+PS  
Sbjct: 368 TAVQTA----------QAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ 417

Query: 494 ---------DSVSSTPAAT-----STPSKQALQ 512
                     +VSS PA +      +PS Q  Q
Sbjct: 418 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ 450



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 12/91 (13%)

Query: 307 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE---------AEPQKQVQPQVHT 357
           P   + + P       T T    L LQQ  +Q Q QQ+          + Q+Q Q Q   
Sbjct: 130 PPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQF 189

Query: 358 QAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 388
           QAQ S   Q+    Q  VQ  +Q  +Q   Q
Sbjct: 190 QAQQSAMQQQF---QAVVQQQQQLQQQQQQQ 217


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 120/425 (28%), Positives = 151/425 (35%), Gaps = 45/425 (10%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQL-QQQQLQQQQL--LQLQQLLQQSPPQAPLPMAVSRGLP 60
            Q QQQQ  QQQQQLQQ QQQQL QQQQLQQQQL   Q QQ LQQ   Q            
Sbjct: 3899 QLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQ 3958

Query: 61   PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGM--------ASPGLAAPS 112
             QQ QQ     Q      LLN S    +   QQ Q    G GM        +SPG   P+
Sbjct: 3959 QQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPT 4018

Query: 113  LTPPQLATPNLQQFFPQATRQSLLGPPP-VGVPMNPSQFNLSGRNPQKQARTSSSTTPNR 171
            L    L         P  + ++  GP    G P+        G  P+  A       P+ 
Sbjct: 4019 LL---LTGKEQNTVDPAVSSEATEGPSTHQGGPL------AIGTTPESMATEPGEVKPS- 4068

Query: 172  KDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEAS 231
                SQ + V+ +  P   S +   P     + Q                       EAS
Sbjct: 4069 LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEAS 4128

Query: 232  ELPAKRLRSSEEPTEKEPPGQLQVK----AQPQARMTVPKQT--QTPDLLPEALEAQVLP 285
             +P   L +    +  + PG +        QP     +   T  Q P   P     Q LP
Sbjct: 4129 SVP--HLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLP 4186

Query: 286  --RFQPRVLQVQAQVQS--QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL 341
                 P V Q++AQ+Q      P++     Q Q +LQ     +       LQQ Q   Q 
Sbjct: 4187 GVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQ------LQQSQAVRQT 4240

Query: 342  QQEAEPQKQVQP-QVHTQAQPSV----QPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 396
                EP  Q  P Q     QP +     PQ  P  ++   P  Q   +    P      P
Sbjct: 4241 PPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGP 4300

Query: 397  EQTPV 401
               PV
Sbjct: 4301 VLGPV 4305



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 110/438 (25%), Positives = 163/438 (37%), Gaps = 71/438 (16%)

Query: 4    QQQQQQLQQQQQQ----LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAP-----LPMA 54
            Q+Q  Q+++QQ++    + + + +Q QQQQ QQQQ  Q   +L  SP Q+P     LP  
Sbjct: 3575 QKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQ 3634

Query: 55   VSRGLPPQQPQQP--------LLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYG-MAS 105
            +  G   Q PQ P         L   G        G  L  AL  QQ Q +  G G +A 
Sbjct: 3635 LLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAG 3694

Query: 106  PG-------LAAPSLTPP----------------QLATPNLQQFFPQATRQSLLGPPPVG 142
            P        LA  SL P                 QLA    QQ   Q  +Q LLG   + 
Sbjct: 3695 PSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAI- 3753

Query: 143  VPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKS-DPPEGSEEAAEPRMDT 201
                  Q    G   Q               SS Q + V+  S  PP+G +         
Sbjct: 3754 -----QQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGM------- 3801

Query: 202  PEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQA 261
                 L P    + +++   A  P+       P +++  ++      P    Q +     
Sbjct: 3802 -----LGPAQVAVLQQQHPGALGPQG------PHRQVLMTQSRVLSSPQLAQQGQGLMGH 3850

Query: 262  RMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA 321
            R+   +Q Q      +      L   Q  ++    Q +   QP       Q Q +LQ+Q 
Sbjct: 3851 RLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQ 3910

Query: 322  QTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQT 381
            Q Q   +  + QQ+Q+Q Q  Q+ + Q+Q+Q Q   Q Q     Q+    Q   Q  +Q 
Sbjct: 3911 QLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ-----QQQQQLQQQQQQQQQQ 3965

Query: 382  HEQPHTQPQVSLLAPEQT 399
             +Q   Q Q+ LL   +T
Sbjct: 3966 FQQQQQQQQMGLLNQSRT 3983



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 98/423 (23%), Positives = 148/423 (34%), Gaps = 81/423 (19%)

Query: 4    QQQQQQLQQQQQQL-QQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
            Q++Q QLQQQ+ QL Q+LQQQ   QQQ QQQQ L  Q  +QQ   Q P         P  
Sbjct: 3717 QERQLQLQQQRMQLAQKLQQQ---QQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP 3773

Query: 63   QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPN 122
            Q   P  + QG               LL+QQL                 S  PPQ     
Sbjct: 3774 QGLMPPSSHQG---------------LLVQQL-----------------SPQPPQ----- 3796

Query: 123  LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVE 182
                      Q +LGP  V V        L  + P +Q   + S   +    + Q   + 
Sbjct: 3797 --------GPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLM 3848

Query: 183  DKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC-EASELPAKRLRSS 241
                     ++  +          L    + +      P    +P     +L  ++    
Sbjct: 3849 GHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQ 3908

Query: 242  EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 301
            ++  +++   QLQ + Q Q +    +Q Q      + L+ Q   + Q +  Q+Q Q Q Q
Sbjct: 3909 QQQLQQQQQQQLQQQQQLQQQQLQQQQQQ------QQLQQQQQQQLQQQQQQLQQQ-QQQ 3961

Query: 302  TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP-----QLQQEAEP--------- 347
             Q +      Q Q  L  Q++T  SP+    QQ  + P      LQ  + P         
Sbjct: 3962 QQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLL 4021

Query: 348  ----QKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVS------LLAPE 397
                Q  V P V ++A       +  P  +   P     E    +P +S      L+ P+
Sbjct: 4022 TGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQ 4081

Query: 398  QTP 400
              P
Sbjct: 4082 PQP 4084



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 84/302 (27%), Positives = 117/302 (38%), Gaps = 41/302 (13%)

Query: 106 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 165
           P      L+PP   +P      P+A+R   L PPP   PM+P         P + +R S 
Sbjct: 601 PPFEESPLSPPPEESPLSPP--PEASR---LSPPPEDSPMSPPPEESPMSPPPEVSRLSP 655

Query: 166 STTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEP 225
               +R     +  P+   S PPE S     P    PE   L P PED        +P P
Sbjct: 656 LPVVSRLSPPPEESPL---SPPPEES-----PTSPPPEASRLSPPPED-----SPTSPPP 702

Query: 226 EPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 285
           E   AS  P   L S   P E+ P   L +  +PQ    +  +++ P L P   E  + P
Sbjct: 703 EDSPASPPPEDSLMSL--PLEESP--LLPLPEEPQ----LCPRSEGPHLSPRPEEPHLSP 754

Query: 286 RFQPRVLQVQA-QVQSQTQPRIPS-TDTQVQPKLQKQAQ---TQTSPEHLVLQQKQVQPQ 340
           R +   L  QA +     QP  P       +P L  QA+       PE L L  +  +P 
Sbjct: 755 RPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH 814

Query: 341 LQQ-EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP-PEQTHEQPHTQPQVSLLAPEQ 398
           L     EP    QP+     +  + PQ   P    + P PE++H  P  +       PE+
Sbjct: 815 LSPVPEEPCLSPQPE-----ESHLSPQSEEPC---LSPRPEESHLSPELEKPPLSPRPEK 866

Query: 399 TP 400
            P
Sbjct: 867 PP 868



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 123/493 (24%), Positives = 168/493 (34%), Gaps = 100/493 (20%)

Query: 1    MFSQQQQQQLQQQQQQ-----LQQLQQQQLQ---------------QQQLQQQQLLQLQQ 40
            + + QQQQQ QQ QQQ     L  LQQ  +                QQ  QQQQL Q QQ
Sbjct: 3852 LVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQ 3911

Query: 41   LLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRG 100
            L QQ   Q      + +    QQ QQ  L  Q           + Q+    QQ Q   + 
Sbjct: 3912 LQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQ--QQQQQQFQQQ 3969

Query: 101  YGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQ-FNLSGR---- 155
                  GL   S T   L +P  QQ      +Q  LGP   G+P  P Q F+  G     
Sbjct: 3970 QQQQQMGLLNQSRT---LLSPQQQQ-----QQQVALGP---GMPAKPLQHFSSPGALGPT 4018

Query: 156  -----NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPC 210
                   Q     + S+      S+ Q  P+   + P   + E  E +     D  L   
Sbjct: 4019 LLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLV 4078

Query: 211  PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEK-------EPPGQLQVKAQPQARM 263
                      P P+P+P      P  RL   ++              GQL   +  +A  
Sbjct: 4079 ---------QPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEA-S 4128

Query: 264  TVPKQTQTPDL----LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS----------- 308
            +VP     P +     P ++   +L   QP    ++  +Q+ T P+ P            
Sbjct: 4129 SVPHLLAQPSVSLGDQPGSMTQNLLGPQQP---MLERPMQNNTGPQPPKPGPVLQSGQGL 4185

Query: 309  -------TDTQVQPKLQKQAQTQTSPEHL-VLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 360
                   T  Q++ +LQ          HL   QQ+Q+Q  L Q    Q Q   Q     +
Sbjct: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245

Query: 361  PSVQPQEHPPAQ--VSVQPPEQTHEQPHTQPQVSLLA---PEQTPVVVHVCGLEMPPDAV 415
            P  Q     P Q  +  QP       P T P   L A   P+  P       L  PP A+
Sbjct: 4246 PGTQTS---PLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPP------RLPAPPGAL 4296

Query: 416  EAGGGMEKTLPEP 428
              G  +    P P
Sbjct: 4297 STGPVLGPVHPTP 4309



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 72/299 (24%), Positives = 113/299 (37%), Gaps = 30/299 (10%)

Query: 113 LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS---SSTTP 169
           L+PP   +P      P+A+R   L PPP  +P +P    L    P +++  S     +  
Sbjct: 449 LSPPPEESPTSPP--PEASR---LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503

Query: 170 NRKDSSSQTMPVEDKS-DPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 228
           +    SS   P+E+    PPE  E    P ++TP        P     E+   +P PE  
Sbjct: 504 SPPPESSPFSPLEESPLSPPE--ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561

Query: 229 EASELP-AKRLR-SSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPR 286
             S  P A RL    EE     PP +  +   P+A    P   ++P L P   E+ + P 
Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP-LSPPPEESPLSP- 619

Query: 287 FQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 346
                        S+  P  P  D+ + P   +++     PE   L    V  +L    E
Sbjct: 620 ---------PPEASRLSP--PPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPE 667

Query: 347 PQKQVQPQVHTQAQPSVQPQE-HPPAQVS--VQPPEQTHEQPHTQPQVSLLAPEQTPVV 402
                 P   +   P  +     PP + S    PPE +   P  +  +  L  E++P++
Sbjct: 668 ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 95/416 (22%), Positives = 158/416 (37%), Gaps = 63/416 (15%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQ--------QSPPQAPLPMAV 55
            + ++++LQ++QQ   QLQ  Q QQQQ QQ  LL      Q         SP  A     +
Sbjct: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQL 3313

Query: 56   SRGLP-PQQP--QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPS 112
            S GL   +QP   QPL+  Q    A       LQ+ L       + +G+ ++        
Sbjct: 3314 SLGLAGARQPGLPQPLMPTQPPAHA-------LQQRLAPSMAMVSNQGHMLSGQHGGQAG 3366

Query: 113  LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRK 172
            L P Q + P L         Q  +G  P  + M P Q  +       Q + ++S  P   
Sbjct: 3367 LVPQQSSQPVLS--------QKPMGTMPPSMCMKPQQLAM-------QQQLANSFFP--- 3408

Query: 173  DSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCP------EDIAKEKRTPAPEP 225
            D+       ED  DP   ++  A   +     Q  +   P        +  ++ +  P  
Sbjct: 3409 DTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSS 3468

Query: 226  EPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 285
            +        + + RS+ +P++  P          Q  +    Q Q  + L      Q L 
Sbjct: 3469 DLQNHVAAGSGQERSAGDPSQPRP----NPPTFAQGVINEADQRQYEEWL---FHTQQLL 3521

Query: 286  RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVL-QQKQVQPQLQQE 344
            + Q +VL+ Q  V  +++  + +     +   ++  +       LV  QQ ++Q QL Q 
Sbjct: 3522 QMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQV 3581

Query: 345  AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 400
             + QK+     HT         E+   Q   Q  +Q  +Q H+   V  L+P Q+P
Sbjct: 3582 RKQQKE-----HTNLM-----AEYRNKQQQQQQQQQQQQQQHS--AVLALSPSQSP 3625



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 70/328 (21%), Positives = 108/328 (32%), Gaps = 53/328 (16%)

Query: 102  GMASPG---LAAPSLTPPQLATPN---------LQQFFPQATRQSLLGPPPVGVPMNPSQ 149
            G  SPG   L  P   P Q+ + +         L+  FP A       P P G P  P  
Sbjct: 2152 GPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPM 2211

Query: 150  FNLSGRNPQKQA---RTSSSTTPNRKDSSSQTM-----PVEDKSDPPE----GSEEAAEP 197
               S R    Q     T+   TP  + S+         P  D    PE    G  +A+EP
Sbjct: 2212 LGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEP 2271

Query: 198  RMDTPEDQDLPPCPEDIAKEKRTPAPE---------PEPCEASELPAKRLRSSE------ 242
             +  P   +     E   +E    +P            P   + L    L++ +      
Sbjct: 2272 LLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPL 2331

Query: 243  ----EPTEKEPPGQ-LQVKAQPQARMTVPKQTQTPDLLPEA------LEAQVLPRFQPRV 291
                   E + PG  L+ +  P A+   P     PD+           +  + PR QP  
Sbjct: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391

Query: 292  LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQV 351
             +    +  ++ P  P +     P+ Q  +Q+  +P  L  +     P   +   P    
Sbjct: 2392 PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451

Query: 352  QPQVHTQAQPSVQPQEHPPAQVSVQPPE 379
            +P    Q++    P   PP     QPPE
Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRP---QPPE 2476



 Score = 37.4 bits (85), Expect = 0.057
 Identities = 72/350 (20%), Positives = 121/350 (34%), Gaps = 50/350 (14%)

Query: 180  PVEDKSDPPEGSEEAAEPRMDTPEDQDLP----------PCPEDIAKEKRTPAPEPEPCE 229
            P+  +  PP  ++ A+EPR+ +   +  P          PC   IA  K  PAP      
Sbjct: 3093 PLGPEERPPPAAD-ASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLG 3151

Query: 230  ASELPAKRLRSSEEPTEKEPP----GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 285
                P + +  S +      P    G    KA   A    P    TP  L     + +L 
Sbjct: 3152 LGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLE 3211

Query: 286  RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA 345
            +F+        +  + T P  P+       K++        P    L  + +    ++E 
Sbjct: 3212 KFE-------LESGALTLPGGPAASGDELDKMESSLVASELP----LLIEDLLEHEKKEL 3260

Query: 346  EPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHV 405
            + ++Q+  Q+    Q   Q Q+H  + +S   P Q    PH     SL   +Q       
Sbjct: 3261 QKKQQLSAQLQPAQQQQQQQQQH--SLLSAPGPAQAMSLPHEGSSPSLAGSQQQL----- 3313

Query: 406  CGLEMPPDAVEAGGGMEKTLPEP-VGTQVSMEEIQNESACGLDVGECENRAREMPGVWGA 464
                    ++   G  +  LP+P + TQ     +Q   A  + +    N+   + G  G 
Sbjct: 3314 --------SLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAM--VSNQGHMLSGQHGG 3363

Query: 465  GGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 514
               L   + Q S     S  P+  +P    S+   P   +   + A  FF
Sbjct: 3364 QAGL---VPQQSSQPVLSQKPMGTMP---PSMCMKPQQLAMQQQLANSFF 3407



 Score = 37.0 bits (84), Expect = 0.074
 Identities = 74/378 (19%), Positives = 119/378 (31%), Gaps = 57/378 (15%)

Query: 105  SPGLAAPSLTP----PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQ 160
            SP    P L+P    P L+    +      + +  L P P    ++P         P   
Sbjct: 807  SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPEL-----EKPPLS 861

Query: 161  ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDI---AKE 217
             R         +  + + +P+      P  S    EP +  P +  L P PE++      
Sbjct: 862  PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG 921

Query: 218  KRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV------KAQPQARMTVPKQTQT 271
            + + +P+  P +    P   + ++  P    P G+L+        + P++ +  P     
Sbjct: 922  EPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAP----- 976

Query: 272  PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSP--EH 329
                   LE  + P  +      +        P   S      P L +    Q SP  +H
Sbjct: 977  ------ILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH 1030

Query: 330  LVLQQKQVQPQLQQEAEPQKQVQP--------------QVHTQAQPSVQPQEHPPAQVSV 375
             ++ Q     Q    A P     P              ++H      V   E P  +   
Sbjct: 1031 SLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE--- 1087

Query: 376  QPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL---EMPPDAVEAGGGMEKTLPEPVGTQ 432
              P  T   P     +S  AP   P +    GL     P D ++A G      PEP  T 
Sbjct: 1088 --PSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQ----PEPGQTP 1141

Query: 433  VSMEEIQNESACGLDVGE 450
             S+      S   LD  E
Sbjct: 1142 GSLASELKGSPVLLDPEE 1159



 Score = 30.8 bits (68), Expect = 5.3
 Identities = 69/273 (25%), Positives = 99/273 (36%), Gaps = 70/273 (25%)

Query: 5    QQQQQLQQQQQQLQQLQ-QQQLQQQQLQQQQLLQLQQLLQQSP-------PQAPLPMAVS 56
            Q + + Q+Q+Q+L++L  +QQ+Q+  L+Q++           P       P +P    +S
Sbjct: 2674 QTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLS 2733

Query: 57   R---------------GLPPQQPQQPLL--------------------NLQGTNSASLLN 81
            R               GLPP +   P+L                    +    NS  L+ 
Sbjct: 2734 RGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVG 2793

Query: 82   GS--MLQRA-----LLLQQLQGNLRGYGMASPGLAA--------PSLTPPQLATPNLQQF 126
            GS    QRA     L LQQ Q  L     A+   +         PS   P+L    L   
Sbjct: 2794 GSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGS- 2852

Query: 127  FPQATRQSLLGPP--PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNR-KDSSSQTMPVED 183
             P A   + L  P  PV  P  P+QF     N QK      +  P +      +  PV +
Sbjct: 2853 -PLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSE 2911

Query: 184  KSDP----PEGSEEAAEPRMDTPEDQDLPPCPE 212
              DP    PEG    A   +  P+    PP PE
Sbjct: 2912 --DPHRLAPEGLRGLAVSGL-PPQKPSAPPAPE 2941


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 122/456 (26%), Positives = 167/456 (36%), Gaps = 112/456 (24%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQ------------------------------ 33
            +QQQQQ QQQQQQ QQ QQQQ QQQQ QQQ                              
Sbjct: 2718 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTP 2777

Query: 34   -QLLQLQQLLQQSPPQAPLPMA------------VSRGLPPQQPQQPLLNLQGTNSASLL 80
              L+++Q+   Q PPQ P P A            V    PPQQ    L  +      +LL
Sbjct: 2778 EHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALL 2837

Query: 81   NGSM---LQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLG 137
             G+    LQ A L +     L+  G       AP      LA P +    P A   S   
Sbjct: 2838 TGTTVANLQVARLTRVPTSQLQAQGQMQ--TQAPQPAQVALAKPPVVS-VPAAVVSS--- 2891

Query: 138  PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP 197
            P    +PMN +  +++   PQK A                            G    A+P
Sbjct: 2892 PGVTTLPMNVAGISVAIGQPQKAA----------------------------GQTVVAQP 2923

Query: 198  RMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 257
                   Q L    +   ++++  A +P+  +      +++ + +  T    PG     A
Sbjct: 2924 ----VHMQQLLKLKQQAVQQQK--AIQPQAAQGPAAVQQKITAQQITT----PG-----A 2968

Query: 258  QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 317
            Q +         +T  L     +AQ L   Q    QVQ Q+Q    P++    T V    
Sbjct: 2969 QQKVAYAAQPALKTQFLTTPISQAQKLAGAQ----QVQTQIQVAKLPQVVQQQTPVASIQ 3024

Query: 318  Q-KQAQTQTSPEHLVL-------QQKQVQPQLQQEAE--PQKQVQPQVHTQAQPSVQPQE 367
            Q   A  Q SP+ + L       QQ Q+ P +   A+   QK +Q QV T A   +Q   
Sbjct: 3025 QVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPG 3084

Query: 368  HP-PAQV--SVQPPEQTHEQPHTQPQVSLLAPEQTP 400
             P PAQV  S   P Q  +     P V L  P + P
Sbjct: 3085 APNPAQVPASSDSPSQQPKLQMRVPAVRLKTPTKPP 3120



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 96/423 (22%), Positives = 146/423 (34%), Gaps = 62/423 (14%)

Query: 22   QQQLQQQQLQQQQLLQLQ--QLLQQSPPQAPLPMAVS----RGLPPQQPQ---QPLLNLQ 72
            QQ+ QQ  + Q    Q Q     QQ PP  P P A       G P  QPQ   QP    Q
Sbjct: 2495 QQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQ 2554

Query: 73   GTNSASLLNGSML---QRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQ 129
               + +    ++      A+L   ++ ++ G  M +  ++   +        N     P 
Sbjct: 2555 PVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIV-------NTIAGVPA 2607

Query: 130  ATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPE 189
            AT QS+     +  P+ P      G +   Q    +   P    S +   P        +
Sbjct: 2608 ATFQSI--NKRLASPVAPGALTTPGGSAPAQV-VHTQPPPRAVGSPATATPDLVSMATTQ 2664

Query: 190  GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 249
            G               +L P    +    R+  P+       +LP K +           
Sbjct: 2665 GVRAVTSVTASAVVTTNLTP----VQTPARSLVPQVSQATGVQLPGKTI----------T 2710

Query: 250  PGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPST 309
            P   Q+  Q Q +    +Q Q           Q   + Q +  Q Q Q  + +Q ++P  
Sbjct: 2711 PAHFQLLRQQQQQQQQQQQQQ-----------QQQQQQQQQQQQQQQQTTTTSQVQVPQI 2759

Query: 310  DTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ---VQPQVHTQAQPSVQPQ 366
              Q Q   Q +A  + +PEHL+  QKQ      Q   PQ Q    QP    Q Q S  PQ
Sbjct: 2760 QGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQ 2819

Query: 367  EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL-EMPPDAVEAGGGMEKTL 425
            +  P   +V           T P+   L    T   + V  L  +P   ++A G M+   
Sbjct: 2820 QQSPQLTTV-----------TAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQA 2868

Query: 426  PEP 428
            P+P
Sbjct: 2869 PQP 2871



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 28/120 (23%)

Query: 204  DQDLPPCP------EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 257
            D+ LPP        E IAKEK+  A +              + +++P   +PP       
Sbjct: 2469 DKPLPPIQVASLRAERIAKEKKALADQ--------------QKAQQPAVAQPP------- 2507

Query: 258  QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 317
             PQ +   P Q Q P  LP+   A   P   P  +Q Q Q Q QTQP+      + QP +
Sbjct: 2508 PPQPQPPPPPQ-QPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAI 2566



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 54/247 (21%), Positives = 93/247 (37%), Gaps = 42/247 (17%)

Query: 133 QSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQT-MPVEDKSDPPEGS 191
           Q L+     G+P  P    L+G+   +Q    S+  P +  +S  T +P      PP G 
Sbjct: 506 QQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGV 565

Query: 192 EEAA---------EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSE 242
             AA         +P++   + Q   P      K ++   P P P  +S+LP    + ++
Sbjct: 566 PTAALSSALQFAQQPQVVEAQTQLQIP-----VKTQQPNVPIPAP-PSSQLPIPPSQPAQ 619

Query: 243 EPTEKEPPGQLQVKAQ-----PQ----ARMTVPKQTQTPDLLPEALEAQVLP-------- 285
                  PG++QV+A      PQ     R+ V      P  LP +  + + P        
Sbjct: 620 LALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGP 679

Query: 286 ---------RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336
                    R      +  + V S+T   + S  T+ Q   Q    +Q S +  + +Q  
Sbjct: 680 SPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQIT 739

Query: 337 VQPQLQQ 343
           ++ Q+ Q
Sbjct: 740 LENQVHQ 746



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 64/313 (20%), Positives = 102/313 (32%), Gaps = 51/313 (16%)

Query: 272  PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV 331
            P +   +L A+ + + + + L  Q + Q     + P    Q  P  Q+       P+   
Sbjct: 2473 PPIQVASLRAERIAK-EKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAG 2531

Query: 332  LQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQV 391
             Q     P +Q + +PQ Q QPQ                    VQ P +      T    
Sbjct: 2532 SQPPAGPPAVQPQPQPQPQTQPQ-------------------PVQAPAKAQPAITTGGSA 2572

Query: 392  SLLAPEQTPVVVHVCGLEMPPDAVEAG--------------GGMEKTLPEPVGTQV---- 433
            ++LA     +   V G  MP  AV                   + K L  PV        
Sbjct: 2573 AVLA---GTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTP 2629

Query: 434  ---SMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVP 490
               +  ++ +       VG       ++  +    G   VT + +S   A  T  LTPV 
Sbjct: 2630 GGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTAS---AVVTTNLTPVQ 2686

Query: 491  RPSDSV---SSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHM 547
             P+ S+    S       P K        + +     QQ+ Q    + Q QQ+  + Q  
Sbjct: 2687 TPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQ-QQQQQQQQQQQQQQQQQQQQQQQQQ 2745

Query: 548  SQACLLSLLPVPR 560
             Q    S + VP+
Sbjct: 2746 QQTTTTSQVQVPQ 2758



 Score = 33.9 bits (76), Expect = 0.63
 Identities = 48/190 (25%), Positives = 67/190 (35%), Gaps = 23/190 (12%)

Query: 85   LQRALLLQQLQGNLRGYGMASPG--LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVG 142
            L+ + L Q +Q     YG    G  +A PS  PP+ A P      PQ     L G PP+ 
Sbjct: 1421 LKASRLFQPVQ-----YGQKPEGRTVAFPSTHPPRTAAPTTASAAPQG---PLRGRPPIA 1472

Query: 143  V-PMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDT 201
                NP     +      QA  S+        SS+   P        + + +A+ P    
Sbjct: 1473 TFSANPEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPP 1532

Query: 202  PEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQA 261
            P+    P  P   A +   P     P +A      RL S     E     QL     PQ+
Sbjct: 1533 PQ----PQAPSHAAGQSALPQRLVLPSQAQ----ARLPSG----EVVKIAQLASITGPQS 1580

Query: 262  RMTVPKQTQT 271
            R+  P+   T
Sbjct: 1581 RVAQPETPVT 1590



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 76/291 (26%), Positives = 102/291 (35%), Gaps = 59/291 (20%)

Query: 289 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHL--------VLQQKQVQPQ 340
           P+  Q+  Q QSQ Q   PST   VQ            P  L         L       Q
Sbjct: 520 PQAAQLAGQRQSQQQYD-PSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQ 578

Query: 341 LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHE---QPHTQPQVSLLAPE 397
             Q  E Q Q+Q  V TQ QP+V P   PP+     PP Q  +      T  +V + A +
Sbjct: 579 QPQVVEAQTQLQIPVKTQ-QPNV-PIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQ 636

Query: 398 QTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRARE 457
            + +   V    +P D            P P+ T  S   +   S  G            
Sbjct: 637 LSSLPQMVASTRLPVDPA-------PPCPRPLPTS-STSSLAPVSGSG------------ 676

Query: 458 MPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYI 517
            PG   A  S  V    S+ ++A S V      R    V+S P    +P++ A       
Sbjct: 677 -PGPSPARSS-PVNRPSSATNKALSPV----TSRTPGVVASAPTKPQSPAQNA------- 723

Query: 518 CKASCSSQQEFQDHMSEP-----QHQQRLGEIQH---MSQACLLSLLPVPR 560
                SSQ   QD ++E      Q  QR+ E++     SQ  L  L   PR
Sbjct: 724 ----TSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPR 770


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 123/483 (25%), Positives = 180/483 (37%), Gaps = 92/483 (19%)

Query: 2   FSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSP----PQAPLPMAVSR 57
           F Q QQQQ QQQQQ  QQ QQQQ QQQQ QQ Q    QQ  QQ P    PQ   P  V  
Sbjct: 257 FPQLQQQQQQQQQQ--QQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVP- 313

Query: 58  GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLA---APSLT 114
            +PP   Q P   LQ   +   L      +      L G ++    A P LA    PS  
Sbjct: 314 -VPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHP 372

Query: 115 PPQLATPNLQQF-----FPQATRQSLLGPP--------PVGVPMNPSQFNLSGRNPQKQA 161
           PP     + Q       FPQ +       P        P  VP    Q +L+ ++P    
Sbjct: 373 PPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSP 432

Query: 162 RT----SSSTTPNRKDSSSQTMPVEDKSDP-PEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216
            +    S +++P    +  Q  P   +++P P+G ++        P  Q     P  +  
Sbjct: 433 SSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVM 492

Query: 217 EKRTPAPEPEPCE--ASELPAKRLRSSEEPTEKEP---PGQLQVKAQPQARMTVPKQTQT 271
           +++ P   P+        +P KRL       +  P    GQ+     P    T P  +  
Sbjct: 493 QQQPPNQGPQSLHPGLGGMP-KRLPPGFSAGQANPNFMQGQV-----PSTTATTPGNSGA 546

Query: 272 PDLL--------------PEALEAQVL----PRFQPRVLQVQAQVQSQTQ-----PRIPS 308
           P L               P   + QV        QP ++ +   + +Q       P++  
Sbjct: 547 PQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNL 606

Query: 309 TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQ-----VHTQAQPSV 363
           ++ Q QP+       Q  P  L+   +Q+ P   Q  + Q  + PQ        Q  P  
Sbjct: 607 SNMQGQPQ-------QGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQG 659

Query: 364 QPQEHPPAQ------VSVQPPEQTHEQ-------PHTQ---PQVSLLAPEQTPVVVHVCG 407
           Q   +PP+Q        + PP+Q   Q       PH Q   PQ  +L  +Q P++  +  
Sbjct: 660 QMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLL-QQNPMIEQIMT 718

Query: 408 LEM 410
            +M
Sbjct: 719 NQM 721



 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 111/464 (23%), Positives = 165/464 (35%), Gaps = 83/464 (17%)

Query: 1    MFSQQQQ---QQLQQQQQQLQQLQQQQLQQQQL---QQQQLLQLQQLLQQ-----SPPQA 49
            M  Q QQ    QL    QQ+   Q Q +QQQ     Q   +L   QL+ Q     +PP  
Sbjct: 609  MQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQ 668

Query: 50   PLPMAVSRGLPPQQ------PQQ--PLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGY 101
             L  +  R  PP+Q      PQ   P   + G     LL  + +   ++  Q+QGN + +
Sbjct: 669  NLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQF 728

Query: 102  GMASPGLAAPSLTPPQL---ATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 158
               +     P   P Q+    TPN+Q    Q T Q      P   P+N S   + G   Q
Sbjct: 729  NTQNQSNVMPG--PAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQ 786

Query: 159  -----------KQARTSSSTTPNRKDSSSQTMP----VEDKSDPP-----EGSEEAAE-- 196
                        Q     +TT N   S SQ MP     +    PP     +G+  +    
Sbjct: 787  VLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHF 846

Query: 197  ---------PRMDTPEDQDLPPCPED----IAKEKRTPAPEPEPCEASELPAKR--LRSS 241
                     P    P    +  C ++    + K+    +P       S++ A    + + 
Sbjct: 847  SGHGMSFNAPFSGAPNGNQM-SCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNK 905

Query: 242  EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 301
            +  T    P   + K  P+ +    +   TPD  P  LE       QP +   Q      
Sbjct: 906  QNNTNANKP---KKKKPPRKKKNSQQDLNTPDTRPAGLE----EADQPPLPGEQGINLDN 958

Query: 302  TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 361
            + P++P    +  P    Q   Q          +Q+ PQL Q   P  Q  PQ   Q Q 
Sbjct: 959  SGPKLPEFSNR-PPGYPSQPVEQR-------PLQQMPPQLMQHVAPPPQ-PPQQQPQPQL 1009

Query: 362  SVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHV 405
              Q Q  PP+Q     P+   +Q   Q  + +L  +Q P  V +
Sbjct: 1010 PQQQQPPPPSQ-----PQSQQQQQQQQQMMMMLMMQQDPKSVRL 1048



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 106/448 (23%), Positives = 169/448 (37%), Gaps = 72/448 (16%)

Query: 1    MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-QLQQLLQQSPPQ-----APLPMA 54
            M SQQ  Q +    Q +    Q  LQQ  + +Q +  Q+Q   QQ   Q      P P  
Sbjct: 683  MLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQ 742

Query: 55   VSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGNLRGYGMASPGLAAPS 112
            + RG  P   Q  ++   G  S  +L   G +      +  +QG +      SP +A   
Sbjct: 743  IMRGPTPNM-QGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQH 801

Query: 113  LTPPQLATPN--LQQFFPQAT-RQSLLGPPPV----------------GVPMN------P 147
              P   A  +  L Q  P  + +Q+ + PP V                G+  N      P
Sbjct: 802  GDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAP 861

Query: 148  SQFNLS-GRNP----QKQARTSSSTTPN--RKDSSSQTMPVEDKSDPPEGSEEAAEPRMD 200
            +   +S G+NP     K    +S    N  + D S+    V +K    + +  A +P+  
Sbjct: 862  NGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNK----QNNTNANKPKKK 917

Query: 201  TPEDQDLPPCPEDIAKEKRTPAPEPEPCEASE---LPAKRLRSSEEPTEKEPPGQLQVKA 257
             P     P   ++  ++  TP   P   E ++   LP ++  + +    K P    +   
Sbjct: 918  KP-----PRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLP----EFSN 968

Query: 258  QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 317
            +P    + P + +    +P  L   V P  QP   Q Q Q+  Q QP  PS     QP+ 
Sbjct: 969  RPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPS-----QPQS 1023

Query: 318  QKQAQTQTSPEHLVLQQKQVQ----PQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 373
            Q+Q Q Q     +++ Q+  +    P  Q    P+  + P   +Q  P +Q     P  V
Sbjct: 1024 QQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPD--SQRMP-MQQSGSVPVMV 1080

Query: 374  SVQPPEQTHEQPHTQPQVSLLAPEQTPV 401
            S+Q P      P  Q    +  P  TP+
Sbjct: 1081 SLQGPASVPPSPDKQ---RMPMPVNTPL 1105



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 95/428 (22%), Positives = 153/428 (35%), Gaps = 64/428 (14%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL-PPQ 62
            QQ Q QL QQQQ     Q Q  QQQQ QQQ ++ L  ++QQ P    LP  VS+ + PP+
Sbjct: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML--MMQQDPKSVRLP--VSQNVHPPR 1058

Query: 63   QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPN 122
             P    LN          +GS+     ++  LQG              P+  PP   +P+
Sbjct: 1059 GP----LNPDSQRMPMQQSGSV----PVMVSLQG--------------PASVPP---SPD 1093

Query: 123  LQQFFPQATRQSLLGPPPVGVPMNPSQ----FNLSGRNPQKQARTSSSTTPNRKDSSSQT 178
             Q+            P PV  P+  +     +  S +NP        ++ P    S + +
Sbjct: 1094 KQRM-----------PMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPS 1142

Query: 179  MPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRL 238
            +P    + P        +  M  P+    P      A  ++ P            P   +
Sbjct: 1143 VPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP--NV 1200

Query: 239  RSSEEPTEKEPPGQLQVKA-QPQARMTVPKQTQTPD--LLPEALEAQVLPRFQPRV---L 292
             +  + +  + P +   +   PQ     P  T+  +  L PE L A +   F P++   L
Sbjct: 1201 AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL 1260

Query: 293  QVQAQV-----QSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEP 347
              +  +     Q    P       Q    L        +P+   L    V    Q  +  
Sbjct: 1261 PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA 1320

Query: 348  QKQVQPQVHTQAQPSVQPQEHP-PAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP--VVVH 404
             K+  P    ++ P    +  P P + + + P+ T     +Q   +LL   + P  V+V 
Sbjct: 1321 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLA---SQTNAALLQNVELPRNVLVS 1377

Query: 405  VCGLEMPP 412
               L  PP
Sbjct: 1378 PTPLANPP 1385



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 63/299 (21%), Positives = 94/299 (31%), Gaps = 40/299 (13%)

Query: 116 PQLATPNLQQFFPQATRQSLLGPP-----PVGV--PMNPSQFNLSGRNPQKQARTSSSTT 168
           P L+  ++QQ   Q+     L PP     PV V   MNP+ F    +  Q+Q +      
Sbjct: 219 PLLSGLHIQQ---QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQ 275

Query: 169 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP------- 221
             ++    Q +         +   +   P+   P    +PP    +      P       
Sbjct: 276 QQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSL 335

Query: 222 -----------APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ 270
                      AP P P +        L + + P+   PP     +   QA    P+ + 
Sbjct: 336 GTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSN 395

Query: 271 TPDL-LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 329
                 P+    Q  P   P  LQ         QP + +      P   +Q    +SP  
Sbjct: 396 PGQFTAPQMKSLQGGPSRVPTPLQ---------QPHLTNKSPASSPSSFQQGSPASSPTV 446

Query: 330 LVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPP--AQVSVQPPEQTHEQPH 386
              QQ+      Q    PQ   QP       P VQ    PP    +  QPP Q  +  H
Sbjct: 447 NQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLH 505



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 46/185 (24%), Positives = 71/185 (38%), Gaps = 31/185 (16%)

Query: 198 RMDTPEDQDLPPCPEDIAKEKRTPAPEPE-------PCEASELPAKRLRSSEEPTEKEPP 250
           RM+ P    +PP   +++     P P PE       P   S+     L       +  P 
Sbjct: 175 RMNNPATVMIPP-GGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPS 233

Query: 251 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 310
           G L     P              + P ++  Q+ P   P++ Q Q Q Q Q Q +     
Sbjct: 234 GSLAPPHHP--------------MQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQ----Q 275

Query: 311 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPP 370
            Q Q + Q+Q Q +   +H   Q + ++PQ    A  Q  V P  +     ++QP   PP
Sbjct: 276 QQQQQQQQQQLQARPPQQHQQQQPQGIRPQF--TAPTQVPVPPGWNQLPSGALQP---PP 330

Query: 371 AQVSV 375
           AQ S+
Sbjct: 331 AQGSL 335


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 104/407 (25%), Positives = 160/407 (39%), Gaps = 57/407 (14%)

Query: 23   QQLQQQQLQQQQL---LQLQQLLQQSPPQAPLPMAVSRG------LPPQQPQQPLLNLQG 73
            QQ+  Q ++ Q +   +     +  +P Q  L  A S          P +PQQ  + L  
Sbjct: 2090 QQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTM 2149

Query: 74   TNSASLLNGSMLQRAL-LLQQLQGNLRGYGMASPG----LAAPSLTPPQLATPN--LQQF 126
                 L  G    + L ++ Q QG   G     P     L  P     Q A PN  +Q+F
Sbjct: 2150 AQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRF 2209

Query: 127  F--PQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDK 184
               P AT  +        V    +     G   Q+Q++ S    P  +    +T+P    
Sbjct: 2210 LFTPLATTATTASTTTTTVSTTAA-----GTGEQRQSKLS----PQMQVHQDKTLPPAQS 2260

Query: 185  SD--PPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAK----RL 238
            S   P E   + A+P    P+ Q  P  P    + +  P  + +   +S +P++      
Sbjct: 2261 SSVGPAEAQPQTAQPSAQ-PQPQTQPQSPAQ-PEVQTQPEVQTQTTVSSHVPSEAQPTHA 2318

Query: 239  RSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ----TPDLLPEALEAQVLPR------FQ 288
            +SS+     +   Q  V+ Q   R+  P QT+    TP  L    ++QV          Q
Sbjct: 2319 QSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQ 2378

Query: 289  PRV-LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ------PQL 341
            P   LQ+ +Q Q Q+QP++ S+   +         T +SP    LQ +Q Q      PQL
Sbjct: 2379 PHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQL 2438

Query: 342  QQEAEPQKQVQPQV--HTQAQPSVQPQE---HPPAQVSVQPPEQTHE 383
            QQ+ +   Q+Q QV    QAQ S  PQ+     P Q+      QTH+
Sbjct: 2439 QQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQ 2485



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 49/157 (31%), Positives = 73/157 (46%), Gaps = 11/157 (7%)

Query: 258  QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 316
            Q Q++++   Q      LP A  + V P   QP+  Q  AQ Q QTQP+ P+     QP+
Sbjct: 2238 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2292

Query: 317  LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--KQVQPQVHTQAQPSVQPQEHPPAQVS 374
            +Q Q + QT          + QP   Q ++PQ   Q QPQ + Q Q  V+ Q   P+Q  
Sbjct: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQS--PSQTR 2350

Query: 375  VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 411
            ++P   +   P  Q QV     +  P+  H   L++P
Sbjct: 2351 IRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2386



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 94/422 (22%), Positives = 160/422 (37%), Gaps = 51/422 (12%)

Query: 6    QQQQLQQQQQQLQQLQQQ-----------QLQQQQLQQQQLLQLQQLLQQSPPQAPLPMA 54
            QQ Q++    QL QL Q            Q Q Q   Q QL+     +   P Q  +  A
Sbjct: 2141 QQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAA 2200

Query: 55   VSRGLPPQQPQQPLLNLQGTNSASLLN--------GSMLQRALLLQQLQGNLRGYGMASP 106
            +  G   +    PL     T S +           G   Q  L  Q      +    A  
Sbjct: 2201 MPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQS 2260

Query: 107  GLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSS 166
                P+   PQ A P+ Q             P P   P +P+Q  +  +   +   T SS
Sbjct: 2261 SSVGPAEAQPQTAQPSAQ-------------PQPQTQPQSPAQPEVQTQPEVQTQTTVSS 2307

Query: 167  TTPNRKD---SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDL-PPCPEDIAKEKRTPA 222
              P+      + S    V  +S P    +  +  R+ +P    + P  P  ++  +++  
Sbjct: 2308 HVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQS-- 2365

Query: 223  PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQ 282
             + +   +  +P +   S + P++ +P  Q QV++  Q   +     Q     P   + Q
Sbjct: 2366 -QVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQ 2424

Query: 283  VLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS--PEHLVLQQKQVQPQ 340
            +  + QP+V+ V  Q+Q Q Q       +Q+Q ++  Q Q Q S  P+ + LQ   +  Q
Sbjct: 2425 I-QQPQPQVIAVP-QLQQQVQVL-----SQIQSQVVAQIQAQQSGVPQQIKLQ---LPIQ 2474

Query: 341  LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 400
            +QQ +  Q      V T    SVQ Q     Q+  Q  ++  +Q   + + +L A  Q+ 
Sbjct: 2475 IQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSE 2534

Query: 401  VV 402
            ++
Sbjct: 2535 II 2536



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 90/469 (19%), Positives = 153/469 (32%), Gaps = 62/469 (13%)

Query: 140  PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 199
            P+GVP  P +       PQ++   SS+  P R ++  QT PV  ++   E   E  E R 
Sbjct: 1844 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 1899

Query: 200  DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 258
                 +++     E  AK++           ++  P     S+  P +K     +     
Sbjct: 1900 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 1959

Query: 259  PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 308
               +M +  +  +P  +           F   V Q Q+     QVQ +    IPS     
Sbjct: 1960 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2019

Query: 309  --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 350
              T T  QP+               T+    V+   Q++P +     P +Q         
Sbjct: 2020 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2079

Query: 351  --VQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL 408
              V  Q     Q   Q     P   +V  P      P    Q SL +   T  +      
Sbjct: 2080 TPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTP---GQKSLTSATSTSNI--QSSA 2134

Query: 409  EMPPDAVEAGGGMEKTLPEPV-------GTQVSMEEIQNESACGLDVGECENRAREMPGV 461
              PP   +  G ++ T+ +         G Q     IQ +   G   G+ +   + +  +
Sbjct: 2135 SQPPRPQQ--GQVKLTMAQLTQLTQGHGGNQGLTVVIQGQ---GQTTGQLQLIPQGVTVL 2189

Query: 462  WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS 521
             G G  L    + +   + F   PL      + + ++T + T+  + +  Q         
Sbjct: 2190 PGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQ------SKL 2243

Query: 522  CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEP 570
                Q  QD    P     +G  +   Q    S  P P    +T+ + P
Sbjct: 2244 SPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP----QTQPQSP 2288



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 16/98 (16%)

Query: 3    SQQQQQQLQQQQQQLQQLQQQQLQQQ-----QLQQQQLLQLQQLLQQSPPQAPLPMAVSR 57
            S   + QLQ QQ Q Q +   QLQQQ     Q+Q Q + Q+Q        Q+ +P  +  
Sbjct: 2416 SSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQ------AQQSGVPQQIKL 2469

Query: 58   GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQ 95
             LP Q  Q          +  + N   +Q A + +QLQ
Sbjct: 2470 QLPIQIQQS-----SAVQTHQIQNVVTVQAASVQEQLQ 2502



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%)

Query: 629 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 681
           + D   E +  E+++  ++E+           +GD EE +D ED+EE E+EE+
Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 17/60 (28%), Positives = 26/60 (43%)

Query: 208 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 267
           P  P   A E+  PAP P P   +  P   LRS    + +      Q +  P+ R++ P+
Sbjct: 9   PKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPR 68


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 98/397 (24%), Positives = 149/397 (37%), Gaps = 41/397 (10%)

Query: 13  QQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQ 72
           ++Q L QLQQ Q Q  Q Q Q +LQ   L    PP  P P+    G    QP  P +   
Sbjct: 54  REQHLAQLQQLQ-QMHQKQMQCVLQPHHL--PPPPLPPPPVMPGGGYGDWQPPPPPMPPP 110

Query: 73  GTNSASLLNGSMLQRALLLQQLQG--NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQA 130
              + S       +  +L  Q  G   L    + SP  + P   PP    P  Q + P  
Sbjct: 111 PGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPP--VPPGSYMPPSQSYMPPP 168

Query: 131 TRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEG 190
                  PP    P  P       ++P  Q+  + + + +   SSSQ+     +S  P  
Sbjct: 169 QPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSS 228

Query: 191 SEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP- 249
               + P     + Q L P P       +T   + EP E+    AK   + ++    EP 
Sbjct: 229 QASPSRPSQGHSKSQLLAPPPPSAPPGNKTTV-QQEPLESG---AKNKSTEQQQAAPEPD 284

Query: 250 PGQLQVKAQPQ---ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQ--- 303
           P  +  + Q Q    +  +  Q +T   LP   +  V+ +  P  ++ +  V + +Q   
Sbjct: 285 PSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPE 344

Query: 304 ------PRIPSTDTQVQPKL-QKQAQTQTSPEHLVLQQKQV-----QPQLQQEAEPQKQV 351
                 P +P  + +V P L  ++ Q++   E   L+Q Q      Q   Q     Q Q 
Sbjct: 345 SPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQG 404

Query: 352 QPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 388
             Q HTQ Q  +Q       Q  +QPP      PH Q
Sbjct: 405 IMQKHTQLQQILQQY-----QQIIQPP------PHIQ 430



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 77/296 (26%), Positives = 102/296 (34%), Gaps = 36/296 (12%)

Query: 5   QQQQQLQQQQQQLQQLQQ-----------QQLQQQQLQQQQLLQLQQLLQQSPPQAPLPM 53
           Q+  QLQQ  QQ QQ+ Q            QL+  ++QQQ   Q Q L Q+   +  L  
Sbjct: 407 QKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQ---QFQHLYQEWEREFQLWE 463

Query: 54  AVSRGLPP----QQPQQPLLNLQGTNSA--SLLNGSMLQRALLLQQLQGNLR------GY 101
                 P     Q+ ++     QG   A  S L   +     +  Q  GN+        Y
Sbjct: 464 EQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPY 523

Query: 102 GMASPGLAA--PSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQK 159
               P L    P + PP L  P +    P AT      PPPV  P  P+     G  P  
Sbjct: 524 SQMPPPLPTMPPPVLPPSLPPPVMPPALP-ATVPPPGMPPPVMPPSLPTSVPPPGMPPSL 582

Query: 160 QARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKR 219
            +       P    SS+   PV     PP  S  A  P M  P      P P  I     
Sbjct: 583 SSAGPPPVLPPPSLSSAGPPPV---LPPPSLSSTAPPPVMPLPPLSSATP-PPGIPPPGV 638

Query: 220 TPAPEPEPCEASELPAKRLRSSEEPTEKEP---PGQLQVKAQPQARMTVPKQTQTP 272
                P+   A   PA   +SS+ P +  P   P  +   + P      P Q+  P
Sbjct: 639 PQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGP 694



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 29/120 (24%), Positives = 43/120 (35%), Gaps = 10/120 (8%)

Query: 259 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ 318
           P ++M  P  T  P +LP +L   V+P   P  +           P +P   T V P   
Sbjct: 522 PYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLP---TSVPPPGM 578

Query: 319 KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPP 378
             + +   P  ++       P L     P     P + + A P V P   PP   +  PP
Sbjct: 579 PPSLSSAGPPPVL-----PPPSLSSAGPPPVLPPPSLSSTAPPPVMPL--PPLSSATPPP 631


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 85/324 (26%), Positives = 123/324 (37%), Gaps = 45/324 (13%)

Query: 106  PGLAAPSL---TPPQLAT----PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 158
            PGL +PSL   TP   A     PNL    P  T  S  G P  G+P  PS  +LS   P 
Sbjct: 3127 PGLNSPSLPGFTPSNTALTSPKPNLMGL-PSTTVPSP-GLPTSGLPNKPSSASLSSPTPA 3184

Query: 159  KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 218
            +         P ++    Q  P   +  PP  ++    P++   + Q       +  KEK
Sbjct: 3185 QATMAMGPQQPPQQQQQQQ-QPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEK 3243

Query: 219  RT---------PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 269
                       P P+ E  EA    A  + S+  PT +      Q++A   A  + P   
Sbjct: 3244 EKAHKGKGEPLPVPKKEKGEAPTATAATI-SAPLPTMEYAVDPAQLQALQAALTSDPTAL 3302

Query: 270  QTPDLLPEALEAQVLPRFQPRVL-QVQAQVQS-------------QTQPRIPSTDTQVQP 315
             T   LP       +P F P    Q+   +QS                P +      + P
Sbjct: 3303 LTSQFLP-----YFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSP 3357

Query: 316  K--LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 373
               LQ+  Q Q S +  + QQ+Q Q Q QQ+ + Q+Q      T   P     +  PA+ 
Sbjct: 3358 GSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKE 3417

Query: 374  SVQPPEQTHEQPHTQPQVSLLAPE 397
            S +P     EQ +T  +VS L P+
Sbjct: 3418 SPKP----EEQKNTPREVSPLLPK 3437



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 107/436 (24%), Positives = 152/436 (34%), Gaps = 60/436 (13%)

Query: 1    MFSQQQQQQLQQQQQQLQQLQQQQLQ-------------QQQLQQQQLLQLQQLLQQSPP 47
            M + +QQQQ QQQQQQ QQ QQQQ Q             QQ+LQQQ  L   QL   +P 
Sbjct: 1718 MIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLF--NPT 1775

Query: 48   QAP-LPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASP 106
              P  PM     L  QQ Q  L      ++   LN  +   +L +      L G G   P
Sbjct: 1776 LLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEV---SLPVTSGALTLTGTG---P 1829

Query: 107  GLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSS 166
            GL        Q+   + QQ  PQ  +  L         + PSQ      +P+K+    + 
Sbjct: 1830 GLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQ------HPEKK----NK 1879

Query: 167  TTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE 226
                 K+  SQ      + D  EG E    P+      + LP   +   K++  P    E
Sbjct: 1880 LVIKEKEKESQR-----ERDSAEGGEGNTGPK------ETLPDALKAKEKKELAPGGGSE 1928

Query: 227  PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP--EALEAQVL 284
            P       A   R +      E  G   V    + +  V K+    D     E LE    
Sbjct: 1929 PSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGENLEKLECDSC 1988

Query: 285  PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE 344
             +    +L +++  +   Q   P    +   K  +    +  P         ++PQ  + 
Sbjct: 1989 GKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYP---------LRPQTPEP 2039

Query: 345  AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP---PEQTHEQPHTQPQVSLLAPEQTPV 401
              P     P     A P  QP   P    S  P   P     QP + P   L  P + P+
Sbjct: 2040 PPPPPPPPPPPLPAAPP--QPASTPAIPASAPPITSPTIAPAQP-SVPLTQLSMPMELPI 2096

Query: 402  VVHVCGLEMPPDAVEA 417
               +    MP   + A
Sbjct: 2097 FSPLMMQTMPLQTLPA 2112



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 74/235 (31%), Positives = 99/235 (42%), Gaps = 46/235 (19%)

Query: 3    SQQQQQQLQQQQQQLQQLQQQQLQQQQLQ--QQQLLQLQQL--LQQSPPQAP---LPMAV 55
            S Q  Q  ++Q Q   +LQQQ+  +Q+    QQ+L QL  L  L Q PPQAP    P+  
Sbjct: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQ 2496

Query: 56   SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTP 115
            S   P Q    PL  L  +    L N            L   L  Y      LA PS   
Sbjct: 2497 SSPSPSQLSHLPLKPLHTSTPQQLAN------------LPPQLIPYQCDQCKLAFPSFEH 2544

Query: 116  PQ-------LATPNLQQFFPQATRQSLLGPPPVGVPMNP---SQFNLSGRNPQKQARTSS 165
             Q       L+  N Q   PQ   +SL  P  +  P NP   SQ  LSG  PQ  A  SS
Sbjct: 2545 WQEHQQLHFLSAQN-QFIHPQFLDRSLDMPFMLFDPSNPLLASQL-LSGAIPQIPA--SS 2600

Query: 166  STTPNRKDSSSQTM--PVEDKSDPPEGSEEAA----EPRMD-------TPEDQDL 207
            +T+P+   S+  T+   +E+K+    G  ++     EP+ D       TPE  ++
Sbjct: 2601 ATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQLEI 2655



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 25/218 (11%)

Query: 515  CYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRR 574
            C +C+ +   +  FQ H    +H Q+   + H+ +    +   +    +       P   
Sbjct: 986  CKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGN-----PVHL 1040

Query: 575  WCNTCQLY---------------YMGDLIQHRRTQDHK--IAKQSLRPFCTVCNRYFKTP 617
             CN C  Y               +   L  ++  Q H+  +  +S    C +CN   K  
Sbjct: 1041 KCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAK 1100

Query: 618  RKFVEHVKSQGHK--DKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEE-EDDEDEE 674
               ++HV+S  H+  +  ++L+ L+K +  +DED         C   D EE  ED E   
Sbjct: 1101 LNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPS 1160

Query: 675  EIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDF 712
            E   + E   + +    S  + +   T SP T+  + F
Sbjct: 1161 ETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISF 1198



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 24/49 (48%), Positives = 29/49 (59%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLP 52
            QQ QQ  Q  Q+ +QQ QQ+QLQQQQ Q+ Q  Q +      PP AP P
Sbjct: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP 3410



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 22/55 (40%), Positives = 30/55 (54%)

Query: 10   LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
            L QQ QQ QQ  Q+ +QQQQ +Q Q  Q Q++ QQ P  +  P+      P + P
Sbjct: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDP 3414



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 80/367 (21%), Positives = 137/367 (37%), Gaps = 58/367 (15%)

Query: 292  LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--- 348
            LQ+ A+ +        +     +PKL +    Q  P     +Q Q +P+LQQ+ +P+   
Sbjct: 2407 LQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQ--PNQTQEKQGQPKPELQQQEQPEQKT 2464

Query: 349  ---KQVQPQVHT-----QAQPSVQPQEHPPAQVSVQPPEQTH-----EQPHTQPQVSLLA 395
               +Q  PQ+ +     Q  P   P + P  Q S  P + +H         T  Q++ L 
Sbjct: 2465 NTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLP 2524

Query: 396  PEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 455
            P+  P     C L  P          E         Q+     QN+        +  +R+
Sbjct: 2525 PQLIPYQCDQCKLAFP--------SFEHWQEH---QQLHFLSAQNQ----FIHPQFLDRS 2569

Query: 456  REMP-GVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 514
             +MP  ++     L  + L S          +  +P  S +  STP +T    K+ L+  
Sbjct: 2570 LDMPFMLFDPSNPLLASQLLSG--------AIPQIPASSATSPSTPTSTMNTLKRKLEE- 2620

Query: 515  CYICKASCS-SQQEFQDHMSEPQHQQRL------GEIQHMSQACLLSLLPVPRDVLETED 567
                KAS S  + +      EPQ  +RL       +++ + Q  LL   P  R +L+   
Sbjct: 2621 ----KASASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPT-RKMLDHIA 2675

Query: 568  EEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQ 627
             E   ++     Q+++     + R+ Q   +        C  C   FK       H++S+
Sbjct: 2676 HEVGLKK--RVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSR 2733

Query: 628  GHKDKAK 634
             H  +AK
Sbjct: 2734 -HWHEAK 2739



 Score = 37.4 bits (85), Expect = 0.057
 Identities = 54/261 (20%), Positives = 91/261 (34%), Gaps = 33/261 (12%)

Query: 4    QQQQQQLQQQQQQLQQ----------------LQQQQLQQQQLQQQQLLQLQQLLQQSPP 47
            Q  QQQ QQQQ Q+QQ                LQQQQ Q++    +++ + ++  +    
Sbjct: 3194 QPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQ-QRKDKDSEKVKEKEKAHKGKGE 3252

Query: 48   QAPLP------------MAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQ-L 94
              P+P              +S  LP  +       LQ   +A   + + L  +  L   +
Sbjct: 3253 PLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFV 3312

Query: 95   QGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSG 154
             G    Y    PG        P      L  + P A  Q+L+G  P  +     Q+  S 
Sbjct: 3313 PGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSP-ALSQALMGLSPGSLLQQYQQYQQSL 3371

Query: 155  RNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDI 214
            +   +Q +        ++    Q         PP       +P  ++P+ ++    P ++
Sbjct: 3372 QEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREV 3431

Query: 215  AK--EKRTPAPEPEPCEASEL 233
            +    K    PE E   A  L
Sbjct: 3432 SPLLPKLPEEPEAESKSADSL 3452



 Score = 37.0 bits (84), Expect = 0.074
 Identities = 46/202 (22%), Positives = 74/202 (36%), Gaps = 31/202 (15%)

Query: 153  SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP--PC 210
            +G    K A   S+     ++   Q  P   + + PE  ++   P+   P+   LP  P 
Sbjct: 2425 AGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPE--QKTNTPQQKLPQLVSLPSLPQ 2482

Query: 211  PEDIAKEKRTPAPE--PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP-- 266
            P   A   + P P+  P P + S LP K L +S        P QL      Q ++  P  
Sbjct: 2483 PPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSF 2542

Query: 267  ---------------KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI----- 306
                            Q   P  L  +L+   +  F P    + +Q+ S   P+I     
Sbjct: 2543 EHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFM-LFDPSNPLLASQLLSGAIPQIPASSA 2601

Query: 307  --PSTDTQVQPKLQKQAQTQTS 326
              PST T     L+++ + + S
Sbjct: 2602 TSPSTPTSTMNTLKRKLEEKAS 2623



 Score = 33.9 bits (76), Expect = 0.63
 Identities = 18/50 (36%), Positives = 27/50 (54%)

Query: 315  PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ 364
            P   K+A  +   + +  +Q+Q Q Q QQ+ + Q+Q Q Q   QAQ  VQ
Sbjct: 1704 PSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQ 1753



 Score = 33.5 bits (75), Expect = 0.82
 Identities = 15/34 (44%), Positives = 23/34 (67%)

Query: 661 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISRE 694
           E + EEEE++E+EEE E E+E CK +   ++  E
Sbjct: 469 EEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 6/73 (8%)

Query: 294  VQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQP 353
            + A + S ++P+  +          +Q Q Q        QQ+Q Q Q QQ+A+   Q Q 
Sbjct: 1697 IGANIASPSEPKEANRKKLADMIASRQQQQQQQ------QQQQQQQQQQQQAQTLAQAQA 1750

Query: 354  QVHTQAQPSVQPQ 366
            QV    Q  +Q Q
Sbjct: 1751 QVQAHLQQELQQQ 1763



 Score = 30.8 bits (68), Expect = 5.3
 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 9/54 (16%)

Query: 637 KSLEKEIAGQDEDHFITVDAVGCF---------EGDEEEEEDDEDEEEIEVEEE 681
           KS E + +G  E     V    CF         E +EEEEE++ +EEE E EEE
Sbjct: 429 KSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEE 482



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 14/21 (66%), Positives = 17/21 (80%)

Query: 661 EGDEEEEEDDEDEEEIEVEEE 681
           E +EEEEE +E+EEE E EEE
Sbjct: 464 EEEEEEEEAEEEEEEEEEEEE 484


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 77/252 (30%), Positives = 107/252 (42%), Gaps = 45/252 (17%)

Query: 2    FSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
            + +  ++QL QQQQQ QQ QQQQ QQQQ        +    Q   PQ P       G PP
Sbjct: 2151 YREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGP------GGYPP 2204

Query: 62   ----QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQ 117
                QQ  Q  L LQG+        SM Q A  + QL        M  PGL A S     
Sbjct: 2205 AMQQQQRMQQHLPLQGS--------SMGQMAAQMGQLG------QMGQPGLGADS----- 2245

Query: 118  LATPNLQQFFPQATRQ-----SLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRK 172
              TPN+QQ   Q   Q       +G P    PM+P Q  LSG+ PQ      +S  P ++
Sbjct: 2246 --TPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQ-PQ------ASHLPGQQ 2296

Query: 173  DSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP-PCPEDIAKEKRTPAPEPEPCEAS 231
             ++S +  V   + P +     ++P   +P  +  P P P  ++ +  +P P      AS
Sbjct: 2297 IATSLSNQVRSPA-PVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMAS 2355

Query: 232  ELPAKRLRSSEE 243
             +    L + E+
Sbjct: 2356 SIDQGHLGNPEQ 2367



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 88/353 (24%), Positives = 128/353 (36%), Gaps = 66/353 (18%)

Query: 85   LQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVP 144
            LQ+A L+++    +    +    L +P+  PP   TP  Q   PQ T Q    P P  V 
Sbjct: 1821 LQQAQLMRRRMATMNTRNVPQQSLPSPTSAPP--GTPTQQPSTPQ-TPQPPAQPQPSPVS 1877

Query: 145  MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPED 204
            M+P+ F          ART   TT +    +SQ       + PP  + EAA       + 
Sbjct: 1878 MSPAGF-------PSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQ 1930

Query: 205  QD----------LPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQ 254
            Q           +PP    +     TP  +  P   +     ++     P+   PPGQ Q
Sbjct: 1931 QQHLYRVNINNSMPPGRTGMG----TPGSQMAPVSLNVPRPNQVSGPVMPSM--PPGQWQ 1984

Query: 255  VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDT--Q 312
                PQ                     Q +P     V+ +QAQ  +   PR+PS      
Sbjct: 1985 QAPLPQQ--------------------QPMPGLPRPVISMQAQA-AVAGPRMPSVQPPRS 2023

Query: 313  VQPK-LQKQAQTQTSPEHLVLQQKQVQ-----PQLQQEAEPQKQVQPQVHTQAQPSVQPQ 366
            + P  LQ   +T  SP     QQ+ +      PQL      Q+  +   +   QP +QPQ
Sbjct: 2024 ISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAK---YVANQPGMQPQ 2080

Query: 367  EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGG 419
                +Q  +QP    H+QP  Q   ++ A    P V        PP     GG
Sbjct: 2081 PGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGV--------PPQQQAMGG 2125



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 91/422 (21%), Positives = 147/422 (34%), Gaps = 64/422 (15%)

Query: 7    QQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQ 66
            + +L+QQQ Q  +LQQ QL ++++       + Q    SP  AP      +   PQ PQ 
Sbjct: 1809 KHKLRQQQIQ-HRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQP 1867

Query: 67   PLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQF 126
            P    Q   S   ++ +        Q       G   +      P   PP  A    +Q 
Sbjct: 1868 P---AQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQI 1924

Query: 127  FPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSD 186
              +A +Q  L    +   M P +  +    P  Q    S   P     S   MP    S 
Sbjct: 1925 EREAQQQQHLYRVNINNSMPPGRTGMG--TPGSQMAPVSLNVPRPNQVSGPVMP----SM 1978

Query: 187  PPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK--------RTPAPEPEPCEASELPAKRL 238
            PP   ++A       P+ Q +P  P  +   +        R P+ +P    +       L
Sbjct: 1979 PPGQWQQA-----PLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLL 2033

Query: 239  RSSEEPTEKEPPGQLQ--VKAQPQARMTVPKQ------TQTPDLLPE-------ALEAQV 283
            R+ + P+  +   Q+   +K+ PQ      KQ         P + P+        ++ Q 
Sbjct: 2034 RTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQP 2093

Query: 284  LPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQ-------------TQTSPEHL 330
                QP +  + A      +P +P    Q    L  Q Q                +P++ 
Sbjct: 2094 GMHQQPSLQNLNAMQAGVPRPGVP-PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYR 2152

Query: 331  VLQQKQVQPQLQQEAEPQKQVQPQV------------HTQAQPSVQPQEHPPAQVSVQPP 378
             + ++Q+  Q QQ+ + Q+Q Q Q             H Q Q    P  +PPA    Q  
Sbjct: 2153 EMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRM 2212

Query: 379  EQ 380
            +Q
Sbjct: 2213 QQ 2214



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 87/378 (23%), Positives = 133/378 (35%), Gaps = 70/378 (18%)

Query: 27  QQQLQQQQLLQL-QQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSML 85
           Q++L++++  +L +Q +  + P  P P A    +P  QP +P             NG + 
Sbjct: 624 QKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPP------------NGPLS 671

Query: 86  QRALLLQQLQGNLRGYGMASPGLAAPSLTP--PQLATPNLQQFFPQATRQSLLGPPPVGV 143
                +Q  QG +  +   S G       P  P+ A+P        + + + +G  P G+
Sbjct: 672 LPVNRMQVSQG-MNSFNPMSLGNVQLPQAPMGPRAASP-----MNHSVQMNSMGSVP-GM 724

Query: 144 PMNPSQF----NLSG---RNPQKQARTSSSTTP-NRKDSSSQTMPVEDKSDPPEGSEEAA 195
            ++PS+     N+ G    N   QA   S   P N+  SSS  M V              
Sbjct: 725 AISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSV-------------- 770

Query: 196 EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC-----EASELPAKRLRSSEEPTEKEPP 250
                       PP    +++ +   A  P P      +AS+LP   +  S  P    PP
Sbjct: 771 --------GMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQS--PLHPTPP 820

Query: 251 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS-T 309
                   P  + T P     P + P    A   P      +    Q  + T   +PS T
Sbjct: 821 PASTAAGMPSLQHTTP-----PGMTPPQPAAPTQPSTP---VSSSGQTPTPTPGSVPSAT 872

Query: 310 DTQVQPKLQK--QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQE 367
            TQ  P +Q   QAQ    P+  V       PQ  Q+       QP     +Q +     
Sbjct: 873 QTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDN 932

Query: 368 HPPAQVSVQPPEQTHEQP 385
             P   SV   E   +QP
Sbjct: 933 RVPTPSSVASAETNSQQP 950



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 76/354 (21%), Positives = 127/354 (35%), Gaps = 50/354 (14%)

Query: 20   LQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASL 79
            + Q   Q Q L Q Q       +     Q P    VS+G  P       LN+ G  ++ L
Sbjct: 746  MAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQL 805

Query: 80   LNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPP 139
                + Q  L       +      +      P +TPPQ A P        +T  S  G  
Sbjct: 806  PCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPT-----QPSTPVSSSGQT 860

Query: 140  PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRK----------DSSSQTMPVEDKSDPPE 189
            P   P +      +   P  QA   +  TP  +            SSQ  P    + PP 
Sbjct: 861  PTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPG 920

Query: 190  GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 249
                 A   +D     +  P P  +A  + T + +P P    ++P   +++  +  + EP
Sbjct: 921  TPLSQAAASID-----NRVPTPSSVASAE-TNSQQPGP----DVPVLEMKTETQAEDTEP 970

Query: 250  -PGQLQVKAQPQARMT------VPKQTQTPDLLPEALEAQVLPRFQPRV-LQVQAQVQSQ 301
             PG  + K +P++ M         +  +  D+  +  E   +   +P V ++V+ + +S 
Sbjct: 971  DPG--ESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESS 1028

Query: 302  TQPRIPSTDTQVQPKLQ-------KQAQTQT-------SPEHLVLQQKQVQPQL 341
            +      + +  QP+ +       +QA   T        PE L  +Q  V PQL
Sbjct: 1029 SNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQ-PVDPQL 1081



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 62/240 (25%), Positives = 87/240 (36%), Gaps = 66/240 (27%)

Query: 6    QQQQLQQQQQQLQQLQQQQLQQQ-------------QLQQQQ-------LLQLQQLLQQS 45
            ++Q LQQQQQQ QQ QQQQ QQQ             Q QQ Q        +Q QQ +QQ 
Sbjct: 2156 RRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQH 2215

Query: 46   PP---QAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYG 102
             P    +   MA   G   Q  Q  L    G +S   +  ++ QR L  QQ++  +   G
Sbjct: 2216 LPLQGSSMGQMAAQMGQLGQMGQPGL----GADSTPNIQQALQQRILQQQQMKQQIGSPG 2271

Query: 103  MASP------------------------GLAAPSLTPPQLATPNLQQFFPQATRQSLLGP 138
              +P                         L+    +P  + +P  Q   P ++    + P
Sbjct: 2272 QPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQP 2331

Query: 139  PP---------------VGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVED 183
             P               + V M  S       NP++ A      TP+R   SS+   V D
Sbjct: 2332 QPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGD 2391


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 77/252 (30%), Positives = 107/252 (42%), Gaps = 45/252 (17%)

Query: 2    FSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
            + +  ++QL QQQQQ QQ QQQQ QQQQ        +    Q   PQ P       G PP
Sbjct: 2189 YREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGP------GGYPP 2242

Query: 62   ----QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQ 117
                QQ  Q  L LQG+        SM Q A  + QL        M  PGL A S     
Sbjct: 2243 AMQQQQRMQQHLPLQGS--------SMGQMAAQMGQLG------QMGQPGLGADS----- 2283

Query: 118  LATPNLQQFFPQATRQ-----SLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRK 172
              TPN+QQ   Q   Q       +G P    PM+P Q  LSG+ PQ      +S  P ++
Sbjct: 2284 --TPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQ-PQ------ASHLPGQQ 2334

Query: 173  DSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP-PCPEDIAKEKRTPAPEPEPCEAS 231
             ++S +  V   + P +     ++P   +P  +  P P P  ++ +  +P P      AS
Sbjct: 2335 IATSLSNQVRSPA-PVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMAS 2393

Query: 232  ELPAKRLRSSEE 243
             +    L + E+
Sbjct: 2394 SIDQGHLGNPEQ 2405



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 88/353 (24%), Positives = 128/353 (36%), Gaps = 66/353 (18%)

Query: 85   LQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVP 144
            LQ+A L+++    +    +    L +P+  PP   TP  Q   PQ T Q    P P  V 
Sbjct: 1859 LQQAQLMRRRMATMNTRNVPQQSLPSPTSAPP--GTPTQQPSTPQ-TPQPPAQPQPSPVS 1915

Query: 145  MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPED 204
            M+P+ F          ART   TT +    +SQ       + PP  + EAA       + 
Sbjct: 1916 MSPAGF-------PSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQ 1968

Query: 205  QD----------LPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQ 254
            Q           +PP    +     TP  +  P   +     ++     P+   PPGQ Q
Sbjct: 1969 QQHLYRVNINNSMPPGRTGMG----TPGSQMAPVSLNVPRPNQVSGPVMPSM--PPGQWQ 2022

Query: 255  VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDT--Q 312
                PQ                     Q +P     V+ +QAQ  +   PR+PS      
Sbjct: 2023 QAPLPQQ--------------------QPMPGLPRPVISMQAQA-AVAGPRMPSVQPPRS 2061

Query: 313  VQPK-LQKQAQTQTSPEHLVLQQKQVQ-----PQLQQEAEPQKQVQPQVHTQAQPSVQPQ 366
            + P  LQ   +T  SP     QQ+ +      PQL      Q+  +   +   QP +QPQ
Sbjct: 2062 ISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAK---YVANQPGMQPQ 2118

Query: 367  EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGG 419
                +Q  +QP    H+QP  Q   ++ A    P V        PP     GG
Sbjct: 2119 PGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGV--------PPQQQAMGG 2163



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 91/422 (21%), Positives = 147/422 (34%), Gaps = 64/422 (15%)

Query: 7    QQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQ 66
            + +L+QQQ Q  +LQQ QL ++++       + Q    SP  AP      +   PQ PQ 
Sbjct: 1847 KHKLRQQQIQ-HRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQP 1905

Query: 67   PLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQF 126
            P    Q   S   ++ +        Q       G   +      P   PP  A    +Q 
Sbjct: 1906 P---AQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQI 1962

Query: 127  FPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSD 186
              +A +Q  L    +   M P +  +    P  Q    S   P     S   MP    S 
Sbjct: 1963 EREAQQQQHLYRVNINNSMPPGRTGMG--TPGSQMAPVSLNVPRPNQVSGPVMP----SM 2016

Query: 187  PPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK--------RTPAPEPEPCEASELPAKRL 238
            PP   ++A       P+ Q +P  P  +   +        R P+ +P    +       L
Sbjct: 2017 PPGQWQQA-----PLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLL 2071

Query: 239  RSSEEPTEKEPPGQLQ--VKAQPQARMTVPKQ------TQTPDLLPE-------ALEAQV 283
            R+ + P+  +   Q+   +K+ PQ      KQ         P + P+        ++ Q 
Sbjct: 2072 RTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQP 2131

Query: 284  LPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQ-------------TQTSPEHL 330
                QP +  + A      +P +P    Q    L  Q Q                +P++ 
Sbjct: 2132 GMHQQPSLQNLNAMQAGVPRPGVP-PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYR 2190

Query: 331  VLQQKQVQPQLQQEAEPQKQVQPQV------------HTQAQPSVQPQEHPPAQVSVQPP 378
             + ++Q+  Q QQ+ + Q+Q Q Q             H Q Q    P  +PPA    Q  
Sbjct: 2191 EMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRM 2250

Query: 379  EQ 380
            +Q
Sbjct: 2251 QQ 2252



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 87/378 (23%), Positives = 133/378 (35%), Gaps = 70/378 (18%)

Query: 27  QQQLQQQQLLQL-QQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSML 85
           Q++L++++  +L +Q +  + P  P P A    +P  QP +P             NG + 
Sbjct: 662 QKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPP------------NGPLS 709

Query: 86  QRALLLQQLQGNLRGYGMASPGLAAPSLTP--PQLATPNLQQFFPQATRQSLLGPPPVGV 143
                +Q  QG +  +   S G       P  P+ A+P        + + + +G  P G+
Sbjct: 710 LPVNRMQVSQG-MNSFNPMSLGNVQLPQAPMGPRAASP-----MNHSVQMNSMGSVP-GM 762

Query: 144 PMNPSQF----NLSG---RNPQKQARTSSSTTP-NRKDSSSQTMPVEDKSDPPEGSEEAA 195
            ++PS+     N+ G    N   QA   S   P N+  SSS  M V              
Sbjct: 763 AISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSV-------------- 808

Query: 196 EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC-----EASELPAKRLRSSEEPTEKEPP 250
                       PP    +++ +   A  P P      +AS+LP   +  S  P    PP
Sbjct: 809 --------GMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQS--PLHPTPP 858

Query: 251 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS-T 309
                   P  + T P     P + P    A   P      +    Q  + T   +PS T
Sbjct: 859 PASTAAGMPSLQHTTP-----PGMTPPQPAAPTQPSTP---VSSSGQTPTPTPGSVPSAT 910

Query: 310 DTQVQPKLQK--QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQE 367
            TQ  P +Q   QAQ    P+  V       PQ  Q+       QP     +Q +     
Sbjct: 911 QTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDN 970

Query: 368 HPPAQVSVQPPEQTHEQP 385
             P   SV   E   +QP
Sbjct: 971 RVPTPSSVASAETNSQQP 988



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 76/354 (21%), Positives = 127/354 (35%), Gaps = 50/354 (14%)

Query: 20   LQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASL 79
            + Q   Q Q L Q Q       +     Q P    VS+G  P       LN+ G  ++ L
Sbjct: 784  MAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQL 843

Query: 80   LNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPP 139
                + Q  L       +      +      P +TPPQ A P        +T  S  G  
Sbjct: 844  PCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPT-----QPSTPVSSSGQT 898

Query: 140  PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRK----------DSSSQTMPVEDKSDPPE 189
            P   P +      +   P  QA   +  TP  +            SSQ  P    + PP 
Sbjct: 899  PTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPG 958

Query: 190  GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 249
                 A   +D     +  P P  +A  + T + +P P    ++P   +++  +  + EP
Sbjct: 959  TPLSQAAASID-----NRVPTPSSVASAE-TNSQQPGP----DVPVLEMKTETQAEDTEP 1008

Query: 250  -PGQLQVKAQPQARMT------VPKQTQTPDLLPEALEAQVLPRFQPRV-LQVQAQVQSQ 301
             PG  + K +P++ M         +  +  D+  +  E   +   +P V ++V+ + +S 
Sbjct: 1009 DPG--ESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESS 1066

Query: 302  TQPRIPSTDTQVQPKLQ-------KQAQTQT-------SPEHLVLQQKQVQPQL 341
            +      + +  QP+ +       +QA   T        PE L  +Q  V PQL
Sbjct: 1067 SNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQ-PVDPQL 1119



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 62/240 (25%), Positives = 87/240 (36%), Gaps = 66/240 (27%)

Query: 6    QQQQLQQQQQQLQQLQQQQLQQQ-------------QLQQQQ-------LLQLQQLLQQS 45
            ++Q LQQQQQQ QQ QQQQ QQQ             Q QQ Q        +Q QQ +QQ 
Sbjct: 2194 RRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQH 2253

Query: 46   PP---QAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYG 102
             P    +   MA   G   Q  Q  L    G +S   +  ++ QR L  QQ++  +   G
Sbjct: 2254 LPLQGSSMGQMAAQMGQLGQMGQPGL----GADSTPNIQQALQQRILQQQQMKQQIGSPG 2309

Query: 103  MASP------------------------GLAAPSLTPPQLATPNLQQFFPQATRQSLLGP 138
              +P                         L+    +P  + +P  Q   P ++    + P
Sbjct: 2310 QPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQP 2369

Query: 139  PP---------------VGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVED 183
             P               + V M  S       NP++ A      TP+R   SS+   V D
Sbjct: 2370 QPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGD 2429


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 56/131 (42%), Positives = 62/131 (47%), Gaps = 11/131 (8%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
           QQQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  Q    QA            QQ
Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA------KEQQQQQQ 205

Query: 64  PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAA---PSLTPPQLAT 120
            QQ L   Q      LL    LQ+   L  LQ   +G     PG AA    SL    L+ 
Sbjct: 206 QQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ--RQGLISIPPGQAALPVQSLPQAGLSP 263

Query: 121 PNLQQFFPQAT 131
             +QQ + + T
Sbjct: 264 AEIQQLWKEVT 274



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 55/134 (41%), Positives = 64/134 (47%), Gaps = 17/134 (12%)

Query: 2   FSQQQQQQL-----QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS 56
           F ++QQ+QL     QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ   Q   P   +
Sbjct: 138 FYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 197

Query: 57  RGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPP 116
           +    QQ QQ  L  Q             Q+ L +QQLQ       +   GL   S+ P 
Sbjct: 198 KEQQQQQQQQQQLAAQQL--------VFQQQLLQMQQLQQQQHLLSLQRQGLI--SIPPG 247

Query: 117 QLATPNLQQFFPQA 130
           Q A P   Q  PQA
Sbjct: 248 QAALP--VQSLPQA 259



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 20/159 (12%)

Query: 241 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQ 299
           S + ++K+ P Q+ V     A MT   Q  TP  + + L+ QVL P+    +LQ Q  V 
Sbjct: 75  SPKSSDKQRPLQVPVSV---AMMT--PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVM 129

Query: 300 SQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQA 359
            Q Q        Q+Q   +KQ       E L LQ  Q Q Q QQ+ + Q+Q Q Q   Q 
Sbjct: 130 LQQQ--------QLQEFYKKQQ------EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175

Query: 360 QPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQ 398
           Q   Q Q+    Q    P +Q  EQ   Q Q   LA +Q
Sbjct: 176 QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 36/93 (38%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 5   QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
           QQQQ +  QQQQLQ+    QQ+QL  Q LQQQQ  Q QQ  QQ   Q        +    
Sbjct: 123 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 182

Query: 62  QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQL 94
           QQ QQ      G  +         Q+ L  QQL
Sbjct: 183 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 37/136 (27%), Positives = 54/136 (39%), Gaps = 3/136 (2%)

Query: 254 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQV---QAQVQSQTQPRIPSTD 310
           QV    Q +  + +Q  +P  L   L+ Q     Q + LQ    + Q Q   Q       
Sbjct: 97  QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 156

Query: 311 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPP 370
            Q Q + Q+Q Q Q   +    QQ+Q Q Q QQ+  P KQ + Q   Q Q      +   
Sbjct: 157 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 216

Query: 371 AQVSVQPPEQTHEQPH 386
            Q  +   +Q  +Q H
Sbjct: 217 FQQQLLQMQQLQQQQH 232



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 12/126 (9%)

Query: 277 EALEA--QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 334
           +AL+A  Q+L + Q   L+       Q   ++P +   + P++    Q Q   +  VL  
Sbjct: 56  QALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSP 115

Query: 335 KQVQPQLQQE----------AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQ 384
           +Q+Q  LQQ+           E  K+ Q Q+H Q     Q Q+    Q   Q  +Q  +Q
Sbjct: 116 QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175

Query: 385 PHTQPQ 390
              Q Q
Sbjct: 176 QQQQQQ 181



 Score = 33.5 bits (75), Expect = 0.82
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 12  QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAV--SRGLPPQQPQQPLL 69
           QQQQ LQ  +Q  LQQ   Q   L   +   +Q P Q P+ +A+   + + PQQ QQ +L
Sbjct: 53  QQQQALQAARQLLLQQ---QTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQ-IL 108

Query: 70  NLQGTNSASLLNGSMLQRALLLQQLQ 95
             Q  +   L      Q+A++LQQ Q
Sbjct: 109 QQQVLSPQQLQALLQQQQAVMLQQQQ 134



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 45/168 (26%), Positives = 55/168 (32%), Gaps = 20/168 (11%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
           QQ QQ LQQQ    QQLQ        LQQQQ + LQQ   Q   +        + L  QQ
Sbjct: 102 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155

Query: 64  PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNL 123
            QQ     Q             Q+    QQ Q   +  G  +           QLA   L
Sbjct: 156 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215

Query: 124 --------------QQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP 157
                         QQ      RQ L+  PP    +       +G +P
Sbjct: 216 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 263


>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
          Length = 623

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 56/131 (42%), Positives = 62/131 (47%), Gaps = 11/131 (8%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
           QQQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  Q    QA            QQ
Sbjct: 60  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA------KEQQQQQQ 113

Query: 64  PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAA---PSLTPPQLAT 120
            QQ L   Q      LL    LQ+   L  LQ   +G     PG AA    SL    L+ 
Sbjct: 114 QQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ--RQGLISIPPGQAALPVQSLPQAGLSP 171

Query: 121 PNLQQFFPQAT 131
             +QQ + + T
Sbjct: 172 AEIQQLWKEVT 182



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 55/134 (41%), Positives = 64/134 (47%), Gaps = 17/134 (12%)

Query: 2   FSQQQQQQL-----QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS 56
           F ++QQ+QL     QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ   Q   P   +
Sbjct: 46  FYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 105

Query: 57  RGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPP 116
           +    QQ QQ  L  Q             Q+ L +QQLQ       +   GL   S+ P 
Sbjct: 106 KEQQQQQQQQQQLAAQQL--------VFQQQLLQMQQLQQQQHLLSLQRQGLI--SIPPG 155

Query: 117 QLATPNLQQFFPQA 130
           Q A P   Q  PQA
Sbjct: 156 QAALP--VQSLPQA 167



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 45/132 (34%), Positives = 58/132 (43%), Gaps = 15/132 (11%)

Query: 268 QTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS 326
           Q  TP  + + L+ QVL P+    +LQ Q  V  Q Q        Q+Q   +KQ      
Sbjct: 5   QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQ--------QLQEFYKKQQ----- 51

Query: 327 PEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 386
            E L LQ  Q Q Q QQ+ + Q+Q Q Q   Q Q   Q Q+    Q    P +Q  EQ  
Sbjct: 52  -EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 110

Query: 387 TQPQVSLLAPEQ 398
            Q Q   LA +Q
Sbjct: 111 QQQQQQQLAAQQ 122



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 36/93 (38%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 5   QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
           QQQQ +  QQQQLQ+    QQ+QL  Q LQQQQ  Q QQ  QQ   Q        +    
Sbjct: 31  QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 90

Query: 62  QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQL 94
           QQ QQ      G  +         Q+ L  QQL
Sbjct: 91  QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 123



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 34/241 (14%)

Query: 254 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 313
           QV    Q +  + +Q  +P  L   L+ Q     Q + LQ   +   + Q ++     Q 
Sbjct: 5   QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ---EFYKKQQEQLHLQLLQQ 61

Query: 314 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 373
           Q + Q+Q Q Q   +    QQ+Q Q Q QQ+ + Q+Q  P    + Q   Q Q+   A  
Sbjct: 62  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 121

Query: 374 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQV 433
            +   +Q  +    Q Q  LL+ ++  ++       +PP         +  LP       
Sbjct: 122 QLVFQQQLLQMQQLQQQQHLLSLQRQGLI------SIPPG--------QAALP------- 160

Query: 434 SMEEIQNESACGLDVGECENRAREMPGVWG------AGGSLKVTILQSSDSRAFSTVPLT 487
               +Q+    GL   E +   +E+ GV          G L +T   SS + + +T   +
Sbjct: 161 ----VQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKAS 216

Query: 488 P 488
           P
Sbjct: 217 P 217



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%)

Query: 250 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 301
           P QLQ   Q Q  + + +Q        Q   L  + L+ Q   + Q +  Q Q Q  Q Q
Sbjct: 23  PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 82

Query: 302 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 361
            Q        Q Q + Q+Q Q Q  P     +Q+Q Q Q QQ A  Q   Q Q+    Q 
Sbjct: 83  QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ- 134

Query: 362 SVQPQEH-----PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 416
            +Q Q+H         +S+ PP Q      + PQ  L   E   +   V G+    D   
Sbjct: 135 -LQQQQHLLSLQRQGLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGI 192

Query: 417 AGGGMEKT 424
             GG++ T
Sbjct: 193 KHGGLDLT 200



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 45/168 (26%), Positives = 55/168 (32%), Gaps = 20/168 (11%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
           QQ QQ LQQQ    QQLQ        LQQQQ + LQQ   Q   +        + L  QQ
Sbjct: 10  QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 63

Query: 64  PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNL 123
            QQ     Q             Q+    QQ Q   +  G  +           QLA   L
Sbjct: 64  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 123

Query: 124 --------------QQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP 157
                         QQ      RQ L+  PP    +       +G +P
Sbjct: 124 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 171


>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
          Length = 740

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 55/130 (42%), Positives = 62/130 (47%), Gaps = 10/130 (7%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
           QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ P +             QQ 
Sbjct: 177 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 231

Query: 65  QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAA---PSLTPPQLATP 121
           QQ L   Q      LL    LQ+   L  LQ   +G     PG AA    SL    L+  
Sbjct: 232 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ--RQGLISIPPGQAALPVQSLPQAGLSPA 289

Query: 122 NLQQFFPQAT 131
            +QQ + + T
Sbjct: 290 EIQQLWKEVT 299



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 55/134 (41%), Positives = 64/134 (47%), Gaps = 17/134 (12%)

Query: 2   FSQQQQQQL-----QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS 56
           F ++QQ+QL     QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ   Q   P   +
Sbjct: 163 FYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 222

Query: 57  RGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPP 116
           +    QQ QQ  L  Q             Q+ L +QQLQ       +   GL   S+ P 
Sbjct: 223 KEQQQQQQQQQQLAAQQL--------VFQQQLLQMQQLQQQQHLLSLQRQGLI--SIPPG 272

Query: 117 QLATPNLQQFFPQA 130
           Q A P   Q  PQA
Sbjct: 273 QAALP--VQSLPQA 284



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 47/143 (32%), Positives = 62/143 (43%), Gaps = 15/143 (10%)

Query: 257 AQPQARMTVPKQTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 315
           A P +   +  Q  TP  + + L+ QVL P+    +LQ Q  V  Q Q        Q+Q 
Sbjct: 111 AVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQ--------QLQE 162

Query: 316 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSV 375
             +KQ       E L LQ  Q Q Q QQ+ + Q+Q Q Q   Q Q   Q Q+    Q   
Sbjct: 163 FYKKQQ------EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 216

Query: 376 QPPEQTHEQPHTQPQVSLLAPEQ 398
            P +Q  EQ   Q Q   LA +Q
Sbjct: 217 HPGKQAKEQQQQQQQQQQLAAQQ 239



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 36/93 (38%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 5   QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
           QQQQ +  QQQQLQ+    QQ+QL  Q LQQQQ  Q QQ  QQ   Q        +    
Sbjct: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 207

Query: 62  QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQL 94
           QQ QQ      G  +         Q+ L  QQL
Sbjct: 208 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 34/241 (14%)

Query: 254 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 313
           QV    Q +  + +Q  +P  L   L+ Q     Q + LQ   +   + Q ++     Q 
Sbjct: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ---EFYKKQQEQLHLQLLQQ 178

Query: 314 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 373
           Q + Q+Q Q Q   +    QQ+Q Q Q QQ+ + Q+Q  P    + Q   Q Q+   A  
Sbjct: 179 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 238

Query: 374 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQV 433
            +   +Q  +    Q Q  LL+ ++  ++       +PP         +  LP       
Sbjct: 239 QLVFQQQLLQMQQLQQQQHLLSLQRQGLI------SIPPG--------QAALP------- 277

Query: 434 SMEEIQNESACGLDVGECENRAREMPGVWG------AGGSLKVTILQSSDSRAFSTVPLT 487
               +Q+    GL   E +   +E+ GV          G L +T   SS + + +T   +
Sbjct: 278 ----VQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKAS 333

Query: 488 P 488
           P
Sbjct: 334 P 334



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%)

Query: 250 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 301
           P QLQ   Q Q  + + +Q        Q   L  + L+ Q   + Q +  Q Q Q  Q Q
Sbjct: 140 PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 199

Query: 302 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 361
            Q        Q Q + Q+Q Q Q  P     +Q+Q Q Q QQ A  Q   Q Q+    Q 
Sbjct: 200 QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ- 251

Query: 362 SVQPQEH-----PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 416
            +Q Q+H         +S+ PP Q      + PQ  L   E   +   V G+    D   
Sbjct: 252 -LQQQQHLLSLQRQGLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGI 309

Query: 417 AGGGMEKT 424
             GG++ T
Sbjct: 310 KHGGLDLT 317



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 45/168 (26%), Positives = 55/168 (32%), Gaps = 20/168 (11%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
           QQ QQ LQQQ    QQLQ        LQQQQ + LQQ   Q   +        + L  QQ
Sbjct: 127 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180

Query: 64  PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNL 123
            QQ     Q             Q+    QQ Q   +  G  +           QLA   L
Sbjct: 181 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240

Query: 124 --------------QQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP 157
                         QQ      RQ L+  PP    +       +G +P
Sbjct: 241 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 288


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 49/157 (31%), Positives = 73/157 (46%), Gaps = 11/157 (7%)

Query: 258  QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 316
            Q Q++++   Q      LP A  + V P   QP+  Q  AQ Q QTQP+ P+     QP+
Sbjct: 2364 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2418

Query: 317  LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--KQVQPQVHTQAQPSVQPQEHPPAQVS 374
            +Q Q + QT          + QP   Q ++PQ   Q QPQ + Q Q  V+ Q   P+Q  
Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQS--PSQTR 2476

Query: 375  VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 411
            ++P   +   P  Q QV     +  P+  H   L++P
Sbjct: 2477 IRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2512



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 69/272 (25%), Positives = 104/272 (38%), Gaps = 38/272 (13%)

Query: 129  QATRQSLLGPPPVGVPMNPSQFNLSGRNP----QKQARTSSSTTPNRKDSSSQTMPVEDK 184
            Q T Q  L P  V V   P Q  +    P    Q+   T  +TT     +++ T+     
Sbjct: 2300 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTT-A 2358

Query: 185  SDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEP 244
            +   E  +    P+M   +D+ LPP                 P EA    A+     +  
Sbjct: 2359 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG----------PAEAQPQTAQPSAQPQPQ 2408

Query: 245  TEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL---QVQAQVQSQ 301
            T+ + P Q +V+ QP+    V  QT     +P   +       +P+V    Q Q+ VQ Q
Sbjct: 2409 TQPQSPAQPEVQTQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQ 2464

Query: 302  TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 361
            +  R+ S     Q +++    +Q SP     QQ QVQ    Q    Q     Q+ +Q QP
Sbjct: 2465 SPVRVQSPS---QTRIRPSTPSQLSPG----QQSQVQTTTSQPIPIQPHTSLQIPSQGQP 2517

Query: 362  SVQPQ---------EHPPAQVSVQPPEQTHEQ 384
              QPQ         EH   + S+ P E+   Q
Sbjct: 2518 QSQPQVVMKHNAVIEHLKQKKSMTPAEREENQ 2549



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 40/143 (27%), Positives = 50/143 (34%), Gaps = 8/143 (5%)

Query: 251  GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 310
            GQLQ+  Q    +  P Q     L+  A+    + RF    L   A   S T   + +T 
Sbjct: 2303 GQLQLIPQGVTVLPGPGQ----QLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTA 2358

Query: 311  T----QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQ 366
                 Q Q KL  Q Q          Q   V P   Q    Q   QPQ  TQ Q   QP+
Sbjct: 2359 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2418

Query: 367  EHPPAQVSVQPPEQTHEQPHTQP 389
                 +V  Q    +H     QP
Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQP 2441



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 90/469 (19%), Positives = 153/469 (32%), Gaps = 62/469 (13%)

Query: 140  PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 199
            P+GVP  P +       PQ++   SS+  P R ++  QT PV  ++   E   E  E R 
Sbjct: 1970 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 2025

Query: 200  DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 258
                 +++     E  AK++           ++  P     S+  P +K     +     
Sbjct: 2026 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 2085

Query: 259  PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 308
               +M +  +  +P  +           F   V Q Q+     QVQ +    IPS     
Sbjct: 2086 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2145

Query: 309  --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 350
              T T  QP+               T+    V+   Q++P +     P +Q         
Sbjct: 2146 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2205

Query: 351  --VQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL 408
              V  Q     Q   Q     P   +V  P      P    Q SL +   T  +      
Sbjct: 2206 TPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTP---GQKSLTSATSTSNI--QSSA 2260

Query: 409  EMPPDAVEAGGGMEKTLPEPV-------GTQVSMEEIQNESACGLDVGECENRAREMPGV 461
              PP   +  G ++ T+ +         G Q     IQ +   G   G+ +   + +  +
Sbjct: 2261 SQPPRPQQ--GQVKLTMAQLTQLTQGHGGNQGLTVVIQGQ---GQTTGQLQLIPQGVTVL 2315

Query: 462  WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS 521
             G G  L    + +   + F   PL      + + ++T + T+  + +  Q         
Sbjct: 2316 PGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQ------SKL 2369

Query: 522  CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEP 570
                Q  QD    P     +G  +   Q    S  P P    +T+ + P
Sbjct: 2370 SPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP----QTQPQSP 2414



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%)

Query: 629 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 681
           + D   E +  E+++  ++E+           +GD EE +D ED+EE E+EE+
Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 17/60 (28%), Positives = 26/60 (43%)

Query: 208 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 267
           P  P   A E+  PAP P P   +  P   LRS    + +      Q +  P+ R++ P+
Sbjct: 9   PKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPR 68


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 67/296 (22%), Positives = 114/296 (38%), Gaps = 27/296 (9%)

Query: 138 PPPVGVPMNPSQFNLSGRNPQKQAR----TSSSTTPNRKDSSSQTMPVEDKSDPPEGSEE 193
           PP V   +   Q  L    P+++AR    +++  TP  +  +    P+  ++   E S E
Sbjct: 414 PPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAE 473

Query: 194 -----AAEPRMD-TPEDQDLPPCPEDIAKEK----RTPAPEPEPCEASELPAKRLRSSEE 243
                A EP  D TP +   P   E  A+E     ++P  E    E +    + L + E 
Sbjct: 474 IQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEA 533

Query: 244 PTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA------- 296
           P ++ P       ++  +    P + Q+P     ++E   L    P   +  A       
Sbjct: 534 PADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAI 593

Query: 297 QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVH 356
           Q+ + T+        +VQP   ++A  +  P        +VQP   +EA  + Q  P   
Sbjct: 594 QLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEE 653

Query: 357 TQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 412
             A+    P E  PA+V   P E+         +V  L  E+TP+   +  +  PP
Sbjct: 654 APAEVQPPPAEEAPAEVQPPPAEE------APAEVQSLPAEETPIEETLAAVHSPP 703



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 70/325 (21%), Positives = 119/325 (36%), Gaps = 58/325 (17%)

Query: 172 KDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDL-----PPCPEDIAKEK-------- 218
           +  S+Q  P+E +  P EG+ E A  +++ P  ++      P  PE+  +E+        
Sbjct: 385 RSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLST 444

Query: 219 --RTPA---------PEPEPCEASELPAK-RLRSSEEPTEKEPPGQLQ---------VKA 257
              TPA         P P+   A E  A+ +L ++ EP   E P + +          +A
Sbjct: 445 AMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEA 504

Query: 258 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD--TQVQP 315
             + +  + ++T   +    + E Q+L   +    +  A+ QS       + +   +VQ 
Sbjct: 505 HAEVQSPLAEETTAEE---ASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQS 561

Query: 316 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEA---------------EPQKQVQPQVHTQAQ 360
              K    + +P  L LQ    +    +EA               E   +VQP    +A 
Sbjct: 562 PSAKGVSIEEAP--LELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAP 619

Query: 361 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPE--QTPVVVHVCGLEMPPDAVEAG 418
             VQP     A   VQPP         QP  +  AP   Q P          PP A EA 
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAP 679

Query: 419 GGMEKTLPEPVGTQVSMEEIQNESA 443
             ++    E    + ++  + +  A
Sbjct: 680 AEVQSLPAEETPIEETLAAVHSPPA 704



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 47/209 (22%), Positives = 73/209 (34%), Gaps = 24/209 (11%)

Query: 168 TPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM--------------DTPEDQDLPPCPED 213
           +P+ K  S +  P+E    PP G E  AE                 + P +   PP  E+
Sbjct: 561 SPSAKGVSIEEAPLE--LQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPA-EE 617

Query: 214 IAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPG--QLQVKAQPQARMTVPKQTQT 271
              E + P  E  P E    PA+     E P E +PP   +   + QP      P + Q 
Sbjct: 618 APAEVQPPPAEEAPAEVQPPPAE-----EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 672

Query: 272 PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV 331
           P       E Q LP  +  + +  A V S     +P+ +  V           T    + 
Sbjct: 673 PPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIG 732

Query: 332 LQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 360
               +V P   ++    + +   V T+ Q
Sbjct: 733 EASAEVSPPPSEQTPEDEALVENVSTEFQ 761



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 91/450 (20%), Positives = 160/450 (35%), Gaps = 102/450 (22%)

Query: 153 SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPP-----------------EGS--EE 193
           +  +P+ Q  T+S+    +K+ S  +   E K  PP                 EGS  ++
Sbjct: 192 ASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKK 251

Query: 194 AAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASEL-------------------- 233
            A   ++ P  +  P   +    E+ T   EP P E + +                    
Sbjct: 252 VASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAE 311

Query: 234 --------PAKRLRSSEEPTEKEPPG-------QLQVKAQPQARMTVPKQTQTPDLLPEA 278
                   PA+     E P E +PP        +L  +  P +    P +    ++LP  
Sbjct: 312 NSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPP 371

Query: 279 LE----AQVL-----PRFQPRVLQVQ------------AQVQSQTQPRIPSTDTQVQPKL 317
            E     ++L     P  Q   ++VQ            A+V+    P +  T   VQP L
Sbjct: 372 AEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVE---PPTVEETLADVQPLL 428

Query: 318 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ---------PQEH 368
            ++A  + + E L L      P  +   E Q  + P+  T  + S +         P + 
Sbjct: 429 PEEAPREEARE-LQLSTAMETPAEEAPTEFQSPL-PKETTAEEASAEIQLLAATEPPADE 486

Query: 369 PPAQVSVQPPEQTH-EQPHTQPQVSL----LAPEQTPVVVHVCGLEMPPDAVEAGGGMEK 423
            PA+      E+T  E+ H + Q  L     A E +  +  +  +E P D  E     + 
Sbjct: 487 TPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPAD--ETPAEAQS 544

Query: 424 TLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG--VWGAGGSLKVTILQSSDSRAF 481
            L E    + +  E+Q+ SA G+ + E     +   G        S  + +L ++++ A 
Sbjct: 545 PLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASA- 603

Query: 482 STVPLTPVPRPSDSVSS---TPAATSTPSK 508
              P    P P++   +    P A   P++
Sbjct: 604 EEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 633



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 58/256 (22%), Positives = 107/256 (41%), Gaps = 28/256 (10%)

Query: 206 DLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTV 265
           ++PP  E + KE++T   E E    S   +   +S E+  + +  G++     P+ +   
Sbjct: 144 NIPPV-EKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQ--- 199

Query: 266 PKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 325
           P      ++  + +      +   +   V  + + + +  +P    Q    ++K A  + 
Sbjct: 200 PATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVV--QEGSAVKKVASAEI 257

Query: 326 SPEHLVLQQKQVQPQLQQEAEPQKQVQP--QVHTQAQPSVQPQEHPPAQ---------VS 374
            P        ++QP L +EA  + + +P  + H Q QPS   +E P A+         V 
Sbjct: 258 EPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPST--EETPDAEAATAVAENSVK 315

Query: 375 VQPPEQTHEQPHTQPQVSLLAP--EQTPVVVHVCGLEMPPDAVEAGG--GMEKTLPEPVG 430
           VQPP    E P  +    +  P  E++P V  +  + +PP A E+       + LP P  
Sbjct: 316 VQPP-PAEEAPLVEFPAEIQPPSAEESPSVELLAEI-LPPSAEESPSEEPPAEILPPPAE 373

Query: 431 TQVSME---EIQNESA 443
              S+E   EI++ SA
Sbjct: 374 KSPSVELLGEIRSPSA 389


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 86/345 (24%), Positives = 127/345 (36%), Gaps = 41/345 (11%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           M  QQQ Q  Q Q+QQ  Q QQ+QLQ QQ Q+QQ+LQ Q+ LQQ   +  L       L 
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLAT 120
            QQ  Q    LQ             Q+ LLL Q QG L+   +             QL  
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQ--------QQAQLQQ 264

Query: 121 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 180
             L+Q   Q  +Q LL                     Q+Q +              + + 
Sbjct: 265 QLLEQQQAQLQQQLLL---------------------QQQEQLQQQQQQQLLQQQQEQLQ 303

Query: 181 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 240
            +    PP   EE         E+ +L   P D+  E+       E     EL  ++ + 
Sbjct: 304 QQQLQPPPLEPEE--------EEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQR 355

Query: 241 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 300
             +   +E   QL+ + + Q +    ++ Q  +L P  L AQ     Q  +  VQ ++Q 
Sbjct: 356 QLQLKLQEELQQLEQQLEQQQQQLEQQEVQL-ELTPVELGAQ-QQEVQLELTPVQPELQL 413

Query: 301 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA 345
           +  P        V       A     P ++V+Q+  V P +   A
Sbjct: 414 ELVPAAGGGGAAVPG--APAAVVVAPPGYVVVQELMVLPAVAAPA 456



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 74/256 (28%), Positives = 117/256 (45%), Gaps = 25/256 (9%)

Query: 147 PSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQD 206
           P    LSG +   +++      P  ++SS Q   V   S P   SE A E R   P  ++
Sbjct: 37  PGPDTLSGGSGGSESQEEEE--PQERNSSPQRPAV---SAPVGASEIAEETR---PGQRE 88

Query: 207 LPPCPEDIAKEKRTPAPEPEPC-EASELPAKRLRSSEEPTEKEPPGQLQV-KAQPQARMT 264
           L      + + ++ P P+ +P  E  + P   L   ++P +    GQ Q+ + Q +   +
Sbjct: 89  L-----QLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQD---GQQQLSQLQQEKHQS 140

Query: 265 VPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQ 324
           V  Q   P+L     + Q+    QP+ +Q Q ++Q Q Q ++ +   Q Q  LQ+Q Q Q
Sbjct: 141 VHHQELKPELQLMHQQQQL----QPQQVQEQQRLQQQ-QEQLQTQQAQEQQVLQQQEQLQ 195

Query: 325 TS-PEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEH-PPAQVSVQPPEQTH 382
               E  +LQQ+Q Q Q QQ  + Q+Q+Q Q   Q Q  +Q Q+     Q   Q  +Q  
Sbjct: 196 QQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLL 255

Query: 383 EQPHTQPQVSLLAPEQ 398
           +Q   Q Q  LL  +Q
Sbjct: 256 QQQQAQLQQQLLEQQQ 271



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 5/185 (2%)

Query: 211 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL--QVKAQPQARMTVPKQ 268
           P+ + +++R    + +         + L+  E+  ++    QL  Q + Q Q +  + +Q
Sbjct: 161 PQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ 220

Query: 269 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 328
            Q      +  + Q+  + Q  +LQ Q Q+Q Q    +     Q+Q +L +Q Q Q   +
Sbjct: 221 EQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL---LQQQQAQLQQQLLEQQQAQLQQQ 277

Query: 329 HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 388
            L+ QQ+Q+Q Q QQ+   Q+Q Q Q      P ++P+E    ++ + P +   EQ   Q
Sbjct: 278 LLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQ 337

Query: 389 PQVSL 393
            +  L
Sbjct: 338 QRQEL 342



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 65/261 (24%), Positives = 109/261 (41%), Gaps = 10/261 (3%)

Query: 147 PSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ- 205
           P + N S + P   A   +S          + + ++     PE  ++    ++  P+   
Sbjct: 57  PQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHL 116

Query: 206 DLPPCPEDIAKEKRTPAPEPEPCEASELPAK-RLRSSEEPTEKEPPG-QLQVKAQPQARM 263
           +L   P+   +++ +   + +         K  L+   +  + +P   Q Q + Q Q   
Sbjct: 117 ELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQ 176

Query: 264 TVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQT 323
              +Q Q   +L +  + Q   + Q  + Q Q Q+Q Q Q        Q Q   Q+Q Q 
Sbjct: 177 LQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ-QLLQQQEQLQQQQFQQQQEQL 235

Query: 324 QTSPEHLVLQQK-QVQPQL--QQEAEPQKQV--QPQVHTQAQPSVQPQEHPPAQVSVQPP 378
           Q   + L+LQQ+ Q+Q QL  QQ+A+ Q+Q+  Q Q   Q Q  +Q QE    Q   Q  
Sbjct: 236 QQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLL 295

Query: 379 EQTHEQ-PHTQPQVSLLAPEQ 398
           +Q  EQ    Q Q   L PE+
Sbjct: 296 QQQQEQLQQQQLQPPPLEPEE 316



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 110/434 (25%), Positives = 157/434 (36%), Gaps = 94/434 (21%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQ----LQQQQLQ--QQQLLQLQQLLQQS------PPQAPL 51
           Q +QQ   QQQ Q +QLQQ Q    LQQQ  Q  QQQL QLQQ   QS       P+  L
Sbjct: 93  QLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQL 152

Query: 52  --------PMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRAL----LLQQLQGNLR 99
                   P  V      QQ Q+ L   Q      L     LQ+ +    LLQQ Q  L+
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212

Query: 100 GYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR-NPQ 158
              +             QL     QQ   Q  +Q  L        +   Q  L  +   Q
Sbjct: 213 QQQLLQ--------QQEQLQQQQFQQQQEQLQQQQQL-------LLLQQQGQLQQQLLQQ 257

Query: 159 KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 218
           +QA+        ++    Q + ++ +           E      + Q L    E + +++
Sbjct: 258 QQAQLQQQLLEQQQAQLQQQLLLQQQ-----------EQLQQQQQQQLLQQQQEQLQQQQ 306

Query: 219 RTPAP-EPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPE 277
             P P EPE  E  EL    L   +  +E+E   Q Q                       
Sbjct: 307 LQPPPLEPEEEEEVEL---ELMPVDLGSEQELEQQRQ----------------------- 340

Query: 278 ALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQV 337
            LE Q     Q    Q+Q ++Q + Q      + Q Q   Q++ Q + +P  L  QQ++V
Sbjct: 341 ELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEV 400

Query: 338 QPQLQQEAEPQKQVQPQVHTQAQPSV----QPQEHPPAQVSVQPPEQTHEQPHTQPQVSL 393
           Q +L         VQP++  +  P+           PA V V PP     Q     ++ +
Sbjct: 401 QLEL-------TPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQ-----ELMV 448

Query: 394 LAPEQTPVVVHVCG 407
           L     P VV + G
Sbjct: 449 LPAVAAPAVVAIPG 462



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 82/412 (19%), Positives = 153/412 (37%), Gaps = 93/412 (22%)

Query: 12  QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNL 71
           Q++ QLQQL+QQ   QQQ Q +QL            Q P P    +  P Q  QQ L  L
Sbjct: 86  QRELQLQQLEQQPEPQQQPQHEQL------------QQPQPHLELQQQPQQDGQQQLSQL 133

Query: 72  QGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQAT 131
           Q     S+ +          Q+L+                    P+L   + QQ      
Sbjct: 134 QQEKHQSVHH----------QELK--------------------PELQLMHQQQ------ 157

Query: 132 RQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGS 191
                        + P Q     R  Q+Q +  +     ++    Q +  +++       
Sbjct: 158 ------------QLQPQQVQEQQRLQQQQEQLQT-----QQAQEQQVLQQQEQLQQQVQE 200

Query: 192 EEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPG 251
           ++  + + +  + Q L    E + +++     E            +L+  ++    +  G
Sbjct: 201 QQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQE------------QLQQQQQLLLLQQQG 248

Query: 252 QLQVK------AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPR 305
           QLQ +      AQ Q ++   +Q Q    L    + Q+  + Q ++LQ Q +   Q Q +
Sbjct: 249 QLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQ 308

Query: 306 IPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE---PQKQVQ-------PQV 355
            P  + + + +++ +           L+Q++ + + QQE E    Q+Q+Q        Q+
Sbjct: 309 PPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQL 368

Query: 356 HTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCG 407
             Q +   Q  E    Q+ + P E   +Q   Q +++ + PE    +V   G
Sbjct: 369 EQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAG 420


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 74/260 (28%), Positives = 94/260 (36%), Gaps = 33/260 (12%)

Query: 137 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 196
           GPPP+  P  P  F +  R P    R      P   D +   MP      PP G      
Sbjct: 42  GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96

Query: 197 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK 256
           P    P    +PP P  +        P   P  A   PA           K P G++   
Sbjct: 97  PPFMPPPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150

Query: 257 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 316
               AR      T+ PD +    ++++ P     +L  QAQVQ+Q Q +      Q Q +
Sbjct: 151 ---NARTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQAQ-----AQAQAQ 196

Query: 317 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ 376
            Q QAQ Q         Q Q Q Q Q +A+ Q Q Q Q   QAQ   Q Q     Q  VQ
Sbjct: 197 AQAQAQAQA--------QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQ 248

Query: 377 PPEQTHEQPHTQPQVSLLAP 396
              Q      + P  S  AP
Sbjct: 249 AQVQAQAVGASTPTTSSPAP 268



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 87/420 (20%), Positives = 140/420 (33%), Gaps = 41/420 (9%)

Query: 26  QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84
           + ++    +L   QQ   +    AP P AV RG PP  +P  P   ++G           
Sbjct: 10  ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPP------ 63

Query: 85  LQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQ--FFPQATRQSLLGPPPVG 142
                   +       +    P +  P   PP +  P+LQ+  F P         PPP G
Sbjct: 64  --------RPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM---PPPPG 112

Query: 143 VPMNPSQFNLSGRN----PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPR 198
           +   P    ++       P  +     + TP+ K         E     P+G +   +  
Sbjct: 113 MMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSE 172

Query: 199 MDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 258
           + TP              + +  A      +A +  A+    ++   + +   Q Q +AQ
Sbjct: 173 L-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQAQAQAQAQAQAQAQAQAQ 230

Query: 259 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ 318
            QA+     Q Q    +   ++AQ +    P        V + T    PS+ T       
Sbjct: 231 AQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTAT 290

Query: 319 KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPP 378
             AQT ++P      Q Q        A P   V     T       PQ HP       PP
Sbjct: 291 SVAQTVSTP----TTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHP----QTLPP 342

Query: 379 EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGG---GMEKTLPEPVGTQVSM 435
                 PH+ PQ +   P   PV+V    + +P   +   G   GM   +   +  QV++
Sbjct: 343 ----AVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAI 398



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 76/302 (25%), Positives = 105/302 (34%), Gaps = 50/302 (16%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62
           Q Q Q Q Q Q   Q Q Q   Q Q+Q Q   Q+Q Q +  S P    P  AVS      
Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277

Query: 63  QPQQPLLNLQGTNSASLLNGSMLQR-ALLLQQLQGNLRGYGMASPGLA----APSLTPPQ 117
            P         T S +    S+ Q  +    Q Q       +A+P ++    AP+ TP Q
Sbjct: 278 TP-------SSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQ 330

Query: 118 LATPNLQQFFPQATRQSLLGP------------PPVGVPMNPSQFNLSG----------- 154
                  Q  P A   S+  P            PP  VP+      L G           
Sbjct: 331 TVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVP 390

Query: 155 -RNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPED-QDLPPCPE 212
             +PQ     S +T       S  T            +    E   + P++ ++     E
Sbjct: 391 MIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEE 450

Query: 213 DIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEKEPPGQLQVKAQPQARMT 264
            I +  + P+ EP P E       E P K ++     EE TE+E   Q   KA+P A   
Sbjct: 451 KIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQ---KAKPVATAP 507

Query: 265 VP 266
           +P
Sbjct: 508 IP 509


>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
           sapiens]
          Length = 1098

 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 74/260 (28%), Positives = 94/260 (36%), Gaps = 33/260 (12%)

Query: 137 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 196
           GPPP+  P  P  F +  R P    R      P   D +   MP      PP G      
Sbjct: 42  GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96

Query: 197 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK 256
           P    P    +PP P  +        P   P  A   PA           K P G++   
Sbjct: 97  PPFMPPPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150

Query: 257 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 316
               AR      T+ PD +    ++++ P     +L  QAQVQ+Q Q +      Q Q +
Sbjct: 151 ---NARTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQAQ-----AQAQAQ 196

Query: 317 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ 376
            Q QAQ Q         Q Q Q Q Q +A+ Q Q Q Q   QAQ   Q Q     Q  VQ
Sbjct: 197 AQAQAQAQA--------QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQ 248

Query: 377 PPEQTHEQPHTQPQVSLLAP 396
              Q      + P  S  AP
Sbjct: 249 AQVQAQAVGASTPTTSSPAP 268



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 109/556 (19%), Positives = 188/556 (33%), Gaps = 82/556 (14%)

Query: 26  QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84
           + ++    +L   QQ   +    AP P AV RG PP  +P  P   ++G           
Sbjct: 10  ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPP------ 63

Query: 85  LQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQ--FFPQATRQSLLGPPPVG 142
                   +       +    P +  P   PP +  P+LQ+  F P         PPP G
Sbjct: 64  --------RPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM---PPPPG 112

Query: 143 VPMNPSQFNLSGRN----PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPR 198
           +   P    ++       P  +     + TP+ K         E     P+G +   +  
Sbjct: 113 MMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSE 172

Query: 199 MDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 258
           + TP              + +  A      +A +  A+    ++   + +   Q Q +AQ
Sbjct: 173 L-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQAQAQAQAQAQAQAQAQAQ 230

Query: 259 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ 318
            QA+     Q Q    +   ++AQ +    P        V + T    PS+ T       
Sbjct: 231 AQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTAT 290

Query: 319 KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPP 378
             AQT ++P      Q Q        A P   V     T       PQ HP       PP
Sbjct: 291 SVAQTVSTP----TTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHP----QTLPP 342

Query: 379 EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEI 438
                 PH+ PQ +   P   PV+V       PP  V   G     +P P+     M+ +
Sbjct: 343 ----AVPHSVPQPTTAIPAFPPVMV-------PPFRVPLPG-----MPIPLPGVAMMQIV 386

Query: 439 QNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSS 498
               +C         +   +PG+                       P+ P+  P  ++++
Sbjct: 387 ----SCPYVKTVATTKTGVLPGM---------------------APPIVPMIHPQVAIAA 421

Query: 499 TPA--ATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLL--S 554
           +PA  A +T   +  ++     K    + +  +    +PQ  +   +++   +  +   S
Sbjct: 422 SPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPS 481

Query: 555 LLPVPRDVLETEDEEP 570
             P+P   +ETE+E+P
Sbjct: 482 EEPLP---METEEEDP 494



 Score = 33.5 bits (75), Expect = 0.82
 Identities = 46/154 (29%), Positives = 58/154 (37%), Gaps = 21/154 (13%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62
           Q Q Q Q Q Q   Q Q Q   Q Q+Q Q   Q+Q Q +  S P    P  AVS      
Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277

Query: 63  QPQQPLLNLQGTNSASLLNGSMLQR-ALLLQQLQGNLRGYGMASPGLA----APSLTPPQ 117
            P         T S +    S+ Q  +    Q Q       +A+P ++    AP+ TP Q
Sbjct: 278 TP-------SSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQ 330

Query: 118 LATPNLQQFFPQATRQSLLGP-------PPVGVP 144
                  Q  P A   S+  P       PPV VP
Sbjct: 331 TVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVP 364


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 83/367 (22%), Positives = 137/367 (37%), Gaps = 75/367 (20%)

Query: 106   PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR---------- 155
             P    P + PP+   P  +   P A +      PP  VP  P +     +          
Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKPEA---PPPKVPEAPKEVVPEKKVPVPPPKKPE 10547

Query: 156   -NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEE-----------AAEPRMDTPE 203
               P K      +  P +K    + +P + +S PPE  E            AA P+     
Sbjct: 10548 VPPTKVPEVPKAAVPEKK--VPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVT 10605

Query: 204   DQDLPPCPEDIAKEKRTPAPEPE-----PCEASELPAKRLRSS----------------- 241
                +P  P+++  EK+ P P P+     P +  E+P   +                    
Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV 10665

Query: 242   -EEPTE---KEPPGQLQVKAQPQA--RMTVPKQTQTPDLLPEALEAQVLPRFQP-RVLQV 294
              EEP E   +EPP ++  + +P A  ++TVP +   P+    A+ A+  P   P +V +V
Sbjct: 10666 FEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAK-KPELPPVKVPEV 10724

Query: 295   QAQVQSQTQ-----PRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQK 349
               +V  + +     P+ P       P++ K+          V+ +K+V    + E  P K
Sbjct: 10725 PKEVVPEKKVPLVVPKKPEAPPAKVPEVPKE----------VVPEKKVAVPKKPEVPPAK 10774

Query: 350   QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV-VVHVCGL 408
                P+V  +     +P    P +    PPE   E     P+  +   E+ PV V      
Sbjct: 10775 --VPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEP 10832

Query: 409   EMPPDAV 415
             E+PP AV
Sbjct: 10833 EVPPPAV 10839



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 54/248 (21%), Positives = 101/248 (40%), Gaps = 22/248 (8%)

Query: 157   PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216
             P+K         P  K   +    V +    PE       P+ + P    +P  P+    
Sbjct: 9954  PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013

Query: 217   EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP-PGQLQVKAQPQARMTVPKQTQTPDLL 275
             E++ P P P+  EA       +     P +K P P   +V+A P     VPK+     L+
Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKK-----LI 10068

Query: 276   PEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQK 335
             PE  +   +P+      +V+A       P++P     V   +    + +   E  ++ ++
Sbjct: 10069 PEEKKPTPVPK------KVEA-----PPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEE 10117

Query: 336   QVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQ-THEQPHTQPQVSLL 394
             +V P+ ++    +++V P+   + +   + +E PP +  V P E+   E+    P+  +L
Sbjct: 10118 EVLPEEEEVLPEEEEVLPE---EEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVL 10174

Query: 395   APEQTPVV 402
              PE  P V
Sbjct: 10175 -PEVKPKV 10181



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 75/330 (22%), Positives = 130/330 (39%), Gaps = 46/330 (13%)

Query: 105   SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGP-----PPVGVPMNPSQFNLSGRNPQK 159
             +P + A     P +  P + +      +  L+ P     PP  VP  P +       P+K
Sbjct: 10706 APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV-----PEK 10760

Query: 160   Q-ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 218
             + A       P  K       PV ++       E A  P  +  E+ +     E+IA E+
Sbjct: 10761 KVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEE 10820

Query: 219   RTPAP-----EPE--PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQT 271
               P P     EPE  P    E P K +   + P  K+P      + +P+  +  PK    
Sbjct: 10821 EKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPR 10880

Query: 272   P----------DLLPEALEAQVLPRFQ-PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQ 320
             P          D+  +  + + +P+ + P   QV  +V+  T  ++P  + +V+ KL  +
Sbjct: 10881 PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVE-LTPLKVPGGEKKVR-KLLPE 10938

Query: 321   AQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV-SVQPPE 379
              + +   E ++   K V  +  +E EP  +V+P+   + +    P+  PP  V  V+ P 
Sbjct: 10939 RKPEPKEEVVL---KSVLRKRPEEEEP--KVEPKKLEKVKKPAVPEPPPPKPVEEVEVPT 10993

Query: 380   QTHEQ---------PHTQPQVSLLAPEQTP 400
              T  +         P  +P + L APE  P
Sbjct: 10994 VTKRERKIPEPTKVPEIKPAIPLPAPEPKP 11023



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 57/210 (27%), Positives = 85/210 (40%), Gaps = 14/210 (6%)

Query: 222   APEPEPCEASELPAKRLRSSEEPTE-KEPPGQLQVKAQPQARMT-VPKQTQTPDLLPEAL 279
             A E E  E  + P K    SE+    K+PP ++  + +P A++  VPK+    + +    
Sbjct: 10427 AEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPE 10486

Query: 280   EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 339
             E +V P   P VL  +  V  +  P  P+   +  P    +A  +  PE  V     V P
Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKV----PVPP 10542

Query: 340   QLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL-LAPEQ 398
               + E  P K   P+V   A P  +  E  P +    PPE         P+  +  AP +
Sbjct: 10543 PKKPEVPPTK--VPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPK 10600

Query: 399   TPVVVHVCGLEMPPDAVEAGGGMEKTLPEP 428
              P V  V   E P + V      EK +P P
Sbjct: 10601 KPEVTPVKVPEAPKEVVP-----EKKVPVP 10625



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 63/302 (20%), Positives = 118/302 (39%), Gaps = 58/302 (19%)

Query: 139   PPVGVPMNPSQFNLSGRNPQ---KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAA 195
             PP  VP  P +     + P    K+        P +++      PV      P+  E   
Sbjct: 10056 PPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKRE------PVPVPVALPQEEEVLF 10109

Query: 196   EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC--EASELPAKRLRSSEEPTEKEPPGQL 253
             E  +  PE++ LP   E++  E+    PE E    E  E+P         P E+E P + 
Sbjct: 10110 EEEI-VPEEEVLPE-EEEVLPEEEEVLPEEEEVLPEEEEIP---------PEEEEVPPEE 10158

Query: 254   QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQ---PRIPSTD 310
             +    P+    VP++   P++ P+      +P  + +V + +  +  + +    ++P   
Sbjct: 10159 EY--VPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVP 10216

Query: 311   TQVQPK---LQKQ-----AQTQTSPEHLVLQQKQV---QPQLQQEAEPQKQVQPQVHTQA 359
              +V+ K   L K+      +    PE   + ++++    P +++  E      P+V  +A
Sbjct: 10217 KKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKA 10276

Query: 360   QPSV-----QPQEHPPAQVSVQ---------------PPEQTHEQPHTQPQVSLLAPEQT 399
              P       +  E PPA+VS +               PP +  E P   P+  +L P++ 
Sbjct: 10277 VPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKE 10336

Query: 400   PV 401
              V
Sbjct: 10337 AV 10338



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 79/369 (21%), Positives = 148/369 (40%), Gaps = 66/369 (17%)

Query: 115   PPQLATPNLQQFFPQATRQSLLGPP-PVGVPMNPSQFNLSGRN---PQKQARTSSST--T 168
             P +   P  ++F P+      + P  PV  P+   +  ++ +    P+K+    +     
Sbjct: 10156 PEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEV 10215

Query: 169   PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK----------EK 218
             P + +     +P E++  P E +EE  E  +   E  + PP  E++ +          +K
Sbjct: 10216 PKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKK 10275

Query: 219   RTP-APEPEPCEASELPAKRLRSSEE-----PTEKE--PPGQLQ--VKAQPQARMTVPKQ 268
               P AP P P +    PAK  +   E     P +K+  PP ++    K  P+ ++ VPK+
Sbjct: 10276 AVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKK 10335

Query: 269   TQTPDLLPE-ALEAQVLPRFQPRVL---QVQAQVQSQTQPRIPSTDT--QVQPKLQ---- 318
                P       LE +V   F+  V+   +++ +V       IP  +   +V+   +    
Sbjct: 10336 EAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEF 10395

Query: 319   -------KQAQTQTSPEHL---------VLQQKQVQPQLQQEAEPQ-KQVQPQVHTQAQP 361
                    K  Q +   EH          V + ++V+   + +A P+  ++  ++    +P
Sbjct: 10396 HEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKP 10455

Query: 362   --SVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGG 419
                V P++ PPA+V   P +   E+    P+   + P + P V       +PP  V    
Sbjct: 10456 PTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEV-------LPPKEVVP-- 10506

Query: 420   GMEKTLPEP 428
               EK +P P
Sbjct: 10507 --EKKVPVP 10513



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 79/344 (22%), Positives = 132/344 (38%), Gaps = 81/344 (23%)

Query: 139   PPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVED---KSDPPEGSEEAA 195
             PP  VP  P +  L  +        + S  P   +   +  P E+   + + P    E  
Sbjct: 10771 PPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEE 10830

Query: 196   EPRMDTPEDQDLPPCPEDIAKEKRTP------AP---EPEPCEASELPAKRLRSSEEPTE 246
             EP +  P    +P  P+ I  EK+ P      AP   EPEP +  E P  +L+    P  
Sbjct: 10831 EPEVPPPA---VPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKP--KLKPRPPPPP 10885

Query: 247   KEPPGQ------LQVKAQPQARMTVPKQTQTPDLL----------------------PEA 278
               PP +       Q+KA P+ +  VP++ Q P+ +                      PE 
Sbjct: 10886 PAPPKEDVKEKIFQLKAIPKKK--VPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEP 10943

Query: 279   LEAQVL------------PRFQPRVLQ-VQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 325
              E  VL            P+ +P+ L+ V+     +  P  P  + +V P + K+ +   
Sbjct: 10944 KEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEV-PTVTKRERKIP 11002

Query: 326   SPEHLVLQQKQVQPQLQQEA-EPQKQVQPQVHTQAQPSVQPQEHP---PAQVSVQPPEQT 381
              P  +     +++P +   A EP+ + + +V T   P V+P+  P   P  V V   +  
Sbjct: 11003 EPTKV----PEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAE 11058

Query: 382   HEQPH---TQPQVSLL-APEQTPVVVHV--------CGLEMPPD 413
              + P     +P+  +   P++TP  +           G E PPD
Sbjct: 11059 AKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPD 11102



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 45/262 (17%), Positives = 105/262 (40%), Gaps = 34/262 (12%)

Query: 198  RMDTPEDQDLPPCPEDIAKEKRTPAPEP---------------EPCEASELPAKRLRSSE 242
            +++ P    +P  P+ I  EK+ PAP P               +P    ++P K ++  E
Sbjct: 9571 KIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEE 9630

Query: 243  EPTEKEPPGQLQVKAQPQARMTVPKQTQTPD---------LLPEALEAQVLPRFQ----P 289
                K     +Q+  + +  + V K+   P           +PE    ++ P+ +     
Sbjct: 9631 PLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPA 9690

Query: 290  RVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQK 349
            +V + + +V  + +  I +   + QP +++    +       L+++ V  Q ++E E  +
Sbjct: 9691 KVTEFRKRVVKEEKVSIEAPKREPQP-IKEVTIMEEKERAYTLEEEAVSVQREEEYEEYE 9749

Query: 350  QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQ--VSLLAPEQTPVVVHVCG 407
            +   +   + +P+ +  ++   +       + HE+  T+P+  + +    + PV      
Sbjct: 9750 EYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKP-- 9807

Query: 408  LEMPPDAVEAGGGMEKTLPEPV 429
             + PP  V      E+ +P P+
Sbjct: 9808 -KAPPAKVLKKAVPEEKVPVPI 9828



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 53/265 (20%), Positives = 101/265 (38%), Gaps = 23/265 (8%)

Query: 179  MPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE----PCEASELP 234
            +P+  K +PP   +    P+   PE++   P P+   KE   P   PE    P    ++P
Sbjct: 9303 VPIPKKVEPP-APKVPEVPKKPVPEEKKPVPVPK---KEPAAPPKVPEVPKKPVPEEKIP 9358

Query: 235  AKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV------LPRFQ 288
                +  E P  K P  Q  V  + +  +   ++   P  +PE  + +V      +PR +
Sbjct: 9359 VPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKE 9418

Query: 289  PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA---QTQTSPEHLVLQQKQVQPQLQQEA 345
              V     +V +  +  +P     V   + K+A   + + S + +V +++ V  +    A
Sbjct: 9419 EEV-PPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFA 9477

Query: 346  EPQKQVQPQVHTQAQPS-VQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVV- 403
             PQ+    +    A+      +E     +SV   E+  E+   +     +  E    VV 
Sbjct: 9478 VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVE 9537

Query: 404  ---HVCGLEMPPDAVEAGGGMEKTL 425
               H+    +  +  E     EK +
Sbjct: 9538 EKLHIISKRVEAEPAEVTERQEKKI 9562



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 54/244 (22%), Positives = 99/244 (40%), Gaps = 40/244 (16%)

Query: 224   EPEPCEASELPAKRLRSSEEPTE-KEPPGQLQVKAQPQARMTVP---KQTQTPDLLPEA- 278
             EPE      +P K +     PT+ K PP ++  KA P+ ++ VP   K    P  +PE  
Sbjct: 9788  EPE----KPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEP 9843

Query: 279   -------LEAQVLPRFQPRVLQVQAQVQSQ-----TQPRIPSTDTQVQPKLQ-KQAQTQT 325
                    +   +  R + +V +  A+V  +      + ++P    +V P ++  +   + 
Sbjct: 9844  KKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKEL 9903

Query: 326   SPEHLVLQQK---QVQPQLQQEAEPQKQVQPQVHTQAQ---------PSVQPQEHPPAQV 373
              PE +  +++    V+  L +E E     + +  T+ +         P V  +  P  + 
Sbjct: 9904  EPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKK 9963

Query: 374   SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA----VEAGGGMEKTLPEPV 429
              V  P++    P   P+V     E+ PV++     E PP A    V      E+ +P PV
Sbjct: 9964  PVPVPKKKEAPPAKVPEVPKKPEEKVPVLIP--KKEKPPPAKVPEVPKKPVPEEKVPVPV 10021

Query: 430   GTQV 433
               +V
Sbjct: 10022 PKKV 10025



 Score = 37.4 bits (85), Expect = 0.057
 Identities = 41/227 (18%), Positives = 87/227 (38%), Gaps = 10/227 (4%)

Query: 163  TSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAA---EPRMDTPEDQDLPPCPEDIAKEKR 219
            T S     R D     M + + +   EG        EPR +     +L    ++I  E +
Sbjct: 8874 TESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELK 8933

Query: 220  TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL 279
             P           +P + +   E P    PP  L +   P+ +   PK+ +      +  
Sbjct: 8934 PPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPT-PEEKKPPPKRIEVTKKAVKKD 8992

Query: 280  EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 339
              +V+ +  P+ +  + ++  +  P      T +  K  +     +  E + +     + 
Sbjct: 8993 AKKVVAK--PKEMTPREEIVKKPPP----PTTLIPAKAPEIIDVSSKAEEVKIMTITRKK 9046

Query: 340  QLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 386
            ++Q+E E   + +  VH + +  ++  E P  ++ V+P  +  EQP+
Sbjct: 9047 EVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPY 9093



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 66/340 (19%), Positives = 124/340 (36%), Gaps = 57/340 (16%)

Query: 189  EGSEEAAEPRMDTPEDQDLPPCPEDI---AKEKRTPAPEPE---PCEASELPAKRLRSSE 242
            EG +E  E   +  +++++    +++   + E++ PA  PE   P     +    +   E
Sbjct: 9131 EGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIE 9190

Query: 243  EPTEKEPPGQLQVKAQPQ-ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 301
            + + +    ++QV   P+ ++  VP++     +  E +E +V     P V   +  +  +
Sbjct: 9191 KTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKV-----PAVHTKKMVISEE 9245

Query: 302  TQPRIPSTDTQVQ---PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQ 358
                   T+ +V    P++QK+  T+      V   K+V+P  +    P+K    +V   
Sbjct: 9246 KMFFASHTEEEVSVTVPEVQKEIVTEEKIH--VAISKRVEPPPKVPELPEKPAPEEVAPV 9303

Query: 359  AQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAG 418
              P       P      + P    ++P   P+    AP + P        E+P   V   
Sbjct: 9304 PIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVP--------EVPKKPVP-- 9353

Query: 419  GGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDS 478
               E+ +P PV         + + A    V E +          G     K+TI+   + 
Sbjct: 9354 ---EEKIPVPVA--------KKKEAPPAKVPEVQK---------GVVTEEKITIVTQREE 9393

Query: 479  RAFSTVP----------LTPVPRPSDSVSSTPAATSTPSK 508
                 VP            PVPR  + V   P   + P K
Sbjct: 9394 SPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKK 9433



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 32/175 (18%), Positives = 72/175 (41%), Gaps = 14/175 (8%)

Query: 211  PEDIAKEKRTPAPEPEPC-EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 269
            PE+I      P P   P  E  + P KR+  +++  +K+    +    +   R  + K+ 
Sbjct: 8954 PEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKP 9013

Query: 270  QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 329
              P  L        +P   P ++ V ++ +      I       + ++QK+ +     + 
Sbjct: 9014 PPPTTL--------IPAKAPEIIDVSSKAEEVKIMTITR-----KKEVQKEKEAVYEKKQ 9060

Query: 330  LVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQ 384
             V ++K+V  +  +E   + +V+P      QP  +  +    ++ V+  ++ HE+
Sbjct: 9061 AVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEE 9115



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 59/291 (20%), Positives = 108/291 (37%), Gaps = 48/291 (16%)

Query: 105  SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 164
            SP  A P +  P+   P  ++  P+   +    PPP  VP  P +               
Sbjct: 9394 SPPPAVPEI--PKKKVPEERKPVPRKEEEV---PPPPKVPALPKK--------------- 9433

Query: 165  SSTTPNRKDSSSQTMPVEDKSDPP----------EGSEEAAEPRMDTPEDQDLPPCPEDI 214
                P  ++  +  +PV  K+ PP          E     AE ++     Q +     ++
Sbjct: 9434 ----PVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEV 9489

Query: 215  AKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDL 274
            + E+     E E  E   +   R    EE  E E   + +V  +P+    V ++      
Sbjct: 9490 SAEEEWSYSEEE--EGVSISVYREEEREEEEEAEVT-EYEVMEEPE-EYVVEEKLHIISK 9545

Query: 275  LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 334
              EA  A+V  R + +++          +P+IP+   +  P    +A  +  PE  V   
Sbjct: 9546 RVEAEPAEVTERQEKKIV---------LKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAP 9596

Query: 335  KQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHP-PAQVSVQPPEQTHEQ 384
               + ++     P++  +P    +  P V   E P PA+V+ +  + T E+
Sbjct: 9597 VPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEE 9647



 Score = 34.7 bits (78), Expect = 0.37
 Identities = 56/302 (18%), Positives = 108/302 (35%), Gaps = 51/302 (16%)

Query: 113   LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP---QKQARTSSSTTP 169
             + P +   P  ++  P A  +    PPP  VP  P +     + P   + +A       P
Sbjct: 10810 IAPEEEIAPEEEKPVPVAEEEEPEVPPPA-VPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868

Query: 170   NRKDSSSQTMPVEDKSDPPEGSEEAAE--------PRMDTPEDQDLPPCPE--------- 212
              +     +  P      P    E+  E        P+   PE   +P   E         
Sbjct: 10869 EKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGG 10928

Query: 213   DIAKEKRTPAPEPEPCEASELPA---------------KRLRSSEEPTEKEPPG-----Q 252
             +    K  P  +PEP E   L +               K+L   ++P   EPP      +
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEE 10988

Query: 253   LQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQ 312
             ++V    +    +P+ T+ P++ P    A  LP  +P+  + +A+V++   P +    T 
Sbjct: 10989 VEVPTVTKRERKIPEPTKVPEIKP----AIPLPAPEPKP-KPEAEVKTIKPPPVEPEPTP 11043

Query: 313   VQ-----PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQE 367
             +      P + K+A+ +   E     +  ++   ++   P +  + ++   +     P E
Sbjct: 11044 IAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDE 11103

Query: 368   HP 369
              P
Sbjct: 11104 AP 11105


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 90/360 (25%), Positives = 113/360 (31%), Gaps = 69/360 (19%)

Query: 106 PGLAAPSLT-PPQLATPNLQQFFPQATRQSLLGP----PPVGVPMNPSQFNLSGRNPQKQ 160
           P  A PS+T PP  A P+LQ   P     SL  P    PP  + ++  Q   S  +P  Q
Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424

Query: 161 ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRT 220
           A  S  T   R+  +S T P    S PP+       P +  P    LP  P         
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPD------SPPLQAP--LSLPASPPLQTSLSPA 476

Query: 221 PAPEPEPCEASELPAKRLRSSEEPTEK-----EPPGQLQVK------AQPQARMTVPKQT 269
            +P   P     L A    +S  P         PP + Q          P A +T P   
Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536

Query: 270 QTPDLLPEALEAQVLPRFQPRV----------LQVQAQVQSQTQPRIPST---------D 310
             P L P  L+    P   P +          LQ      +   P  PS+          
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP 596

Query: 311 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL---QQEAEPQKQVQPQVHTQAQPSVQ--- 364
               P LQ       SP  L     Q  P L     +A P     P +   A PS Q   
Sbjct: 597 ALASPPLQGLPSPPLSP--LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654

Query: 365 ------------PQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 412
                       P   PP Q    PP      P   P      P Q P  +    L++PP
Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP------PSQAPPSLAAPPLQVPP 708



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 84/324 (25%), Positives = 110/324 (33%), Gaps = 52/324 (16%)

Query: 108 LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSST 167
           L++P    P  A  +L    PQA   SL+ PP        +Q +L+   P  Q   +S T
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL------ETQSSLAP--PSLQTPPASLT 531

Query: 168 TPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCP-----EDIAKEKRTPA 222
           TP  ++  S   P    +  P  +     P    P     PP P      +      TP 
Sbjct: 532 TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP 591

Query: 223 PEPEPCEASE----LPAKRLRSSEEPTEKEPPG----QLQVKAQPQARMTV-PKQTQTPD 273
           P+  P  AS     LP+  L     P  + PP      LQ    P A   + P  T +P 
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651

Query: 274 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 333
             P AL   +L                   P  P     VQ      A    SP      
Sbjct: 652 A-PNALAVHLLQA-----------------PFSPPPSPPVQAPFSPPASPPVSPS--ATP 691

Query: 334 QKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVS---VQPPEQTHEQPHTQPQ 390
             Q  P L   A P  QV P     A P + P   PP Q       PP Q    P   P 
Sbjct: 692 PSQAPPSL---AAPPLQVPPS--PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP 746

Query: 391 VSLLA--PEQTPVVVHVCGLEMPP 412
           +S  A  P + P ++    L++PP
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPP 770



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 97/437 (22%), Positives = 155/437 (35%), Gaps = 60/437 (13%)

Query: 96  GNLRGYGMASP---GLAAPSLTPPQLATPNLQQFFPQATRQSL---LGPPPVGVPMNPSQ 149
           G L    +A+P   G  A  + PP  A   L    P +   +    L PP    P +   
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356

Query: 150 FNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPP 209
                  P  QA  S +T P +   S QT+P      P +       P +        PP
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIP------PIQVPHSLTSPSLQA------PP 404

Query: 210 CPEDIAKEKRTPAPEPEPCEASE-----LPAKRLRSSEEPTE--KEPPGQLQVKAQPQAR 262
            P  ++  + T +      +A+       P +   S   P+     PP    ++A     
Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464

Query: 263 MTVPKQTQ-TPDLLPEALEAQVLPRFQPRVL---QVQAQVQSQTQPRIPSTDTQVQPKLQ 318
            + P QT  +P + P +    + P      L     QA + S   P + +  +   P LQ
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524

Query: 319 KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPP 378
               + T+P  L        P LQ  + P     P + T   P+  P + PP+ ++  PP
Sbjct: 525 TPPASLTTPP-LENLPSLAPPPLQTASAP--LTTPHLETPPCPAPCPLQAPPSPLTTPPP 581

Query: 379 EQTHEQPHTQPQVSLLAPEQTPVVVH--VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSME 436
           E       T   ++   P+  P +    + GL  PP +  A      T P      +++ 
Sbjct: 582 E-------TPSSIATPPPQAPPALASPPLQGLPSPPLSPLA------TPPPQAPPXLALP 628

Query: 437 EIQNESA--CGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSD 494
            +Q   +      +      + + P       +L V +LQ+     FS  P  PV  P  
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAP------NALAVHLLQA----PFSPPPSPPVQAPFS 678

Query: 495 SVSSTPAATS-TPSKQA 510
             +S P + S TP  QA
Sbjct: 679 PPASPPVSPSATPPSQA 695



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 74/307 (24%), Positives = 103/307 (33%), Gaps = 45/307 (14%)

Query: 138 PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP 197
           P PV  P   S     G   QK  R S+  T  R  ++          + P+ S  +A  
Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT----------EAPKRSALSAGA 160

Query: 198 RMDTPEDQDLPPCPEDIAKEKRT---------PAPEPEPCEASELPAKRLRSSEE--PTE 246
           R DT       P P  +A+  R          PAP   P   +E P K + S+ E   TE
Sbjct: 161 RRDTSGPTPGTPSPA-MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219

Query: 247 KEPPGQLQVKA-----QPQARMTVPKQTQTPDLLPEALEAQVLPR-----FQPRVLQVQA 296
             P  + +  A     +P +R      T           A+  PR      QP+   +QA
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279

Query: 297 QVQSQ-TQPR---------IPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 346
               Q T PR         + S+          +A+    P++         P     A 
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLAT 339

Query: 347 PQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ-PPEQTHEQPHTQPQVSLLAPEQTPVVVHV 405
           P     P     A PS+Q    PPA    Q PP  T       P +  + P Q P  +  
Sbjct: 340 PLPLAPPS--PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397

Query: 406 CGLEMPP 412
             L+ PP
Sbjct: 398 PSLQAPP 404



 Score = 37.7 bits (86), Expect = 0.043
 Identities = 54/208 (25%), Positives = 70/208 (33%), Gaps = 45/208 (21%)

Query: 46  PPQAPLPMAVSR-GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMA 104
           PPQAP P+A     +PP  P  P ++   T    +     L  A  LQ          M 
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV---PPLLAAPPLQVPPSPPASLPM- 778

Query: 105 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 164
           SP    P   PP LATP LQ           L  PP   P   + F+ S   P      S
Sbjct: 779 SPLAKPPPQAPPALATPPLQ----------ALPSPPASFP-GQAPFSPSASLPM-----S 822

Query: 165 SSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPE 224
              TP                 PP+     A P +  P     PP    +   +R P P 
Sbjct: 823 PLATP-----------------PPQAPPVLAAPLLQVPPS---PPASPTLQAPRRPPTPG 862

Query: 225 PEPCEASELPAKRLRSSEEPTEKEPPGQ 252
           P+    + +   RL  +  P    PP +
Sbjct: 863 PD----TSVSGPRLTLALAPGPPPPPSR 886



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 80/297 (26%), Positives = 99/297 (33%), Gaps = 57/297 (19%)

Query: 42   LQQSP-PQAPLPMAVSRGLPPQQP---QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGN 97
            LQ  P P A LPM+     PPQ P     P L    +  AS    +    +  L      
Sbjct: 766  LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM---- 821

Query: 98   LRGYGMASPGLAAPSLTPPQLATPNLQ-QFFPQA--TRQSLLGPPPVGVPMNPS----QF 150
                   SP    P   PP LA P LQ    P A  T Q+   PP  G   + S      
Sbjct: 822  -------SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874

Query: 151  NLSGRNPQKQARTSSSTTPN---RKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDL 207
             L+   P   +R+ SST         SSS T   E+      G E  A      P D +L
Sbjct: 875  ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA--AASPPPDAEL 932

Query: 208  PPCPEDIAKEKRTPAP---------EPEPCEASELPAK-----RLRSSEEPTEKEP-PGQ 252
              C    A   R PAP          P P   +  P        +  +E P    P PG 
Sbjct: 933  AACHP--AAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 990

Query: 253  LQVKAQP-------------QARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA 296
            L     P              A    PKQ +  +L   AL+A V+     R L + A
Sbjct: 991  LDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA 1047


>gi|197276594 RNA binding motif protein 20 [Homo sapiens]
          Length = 1227

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)

Query: 615  KTPRKFVEHVKSQGH-KDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 673
            + P  FV+  K++G  +D A E   LE++ +   E     +    C E    E     + 
Sbjct: 1057 RQPSPFVDDCKTRGTPEDGACEGSPLEEKASPPIETD---LQNQACQEVLTPENSRYVEM 1113

Query: 674  EEIEVEEELCKQVRSRD-ISREEWKGSETYSP-NTAYGVDFLVPVMGYICRICHKFYHSN 731
            + +EV      +V  +  +S   W+  + +S  +   GV+F+VP  G+ C++C  FY S 
Sbjct: 1114 KSLEVRSPEYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSE 1173

Query: 732  SGAQLSHCKSLGHFENLQKY 751
              A++SHC+S  H+ NLQKY
Sbjct: 1174 ETAKMSHCRSAVHYRNLQKY 1193


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 67/306 (21%), Positives = 117/306 (38%), Gaps = 45/306 (14%)

Query: 184  KSDPPEGSE--EAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSS 241
            +SD  EG E  EA        E  + P    D  + +    PE E  EA E   +    S
Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPES 1887

Query: 242  EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 301
            E+    E   ++Q +++        K+ Q      EALE +                  +
Sbjct: 1888 EDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETE-----------------GE 1930

Query: 302  TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQ--- 358
             +P     + Q   +  ++A+ QT PE  V++ ++ + + Q E+E  + ++ +V TQ   
Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAE 1990

Query: 359  --AQPSVQPQEHPPAQ----------------VSVQPPEQTHEQPHTQPQVSLLAPEQTP 400
              AQP  +  E P A+                V  QP  +  E    + +      +  P
Sbjct: 1991 GEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQP 2050

Query: 401  VVVHVCGLEMPPDAVEAGGGMEKTLPE--PVGTQVSMEEIQNES---ACGLDVGECENRA 455
                V   E   +A EA G +++   E  P    V  +E + E+   + G++  E E  A
Sbjct: 2051 ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEA 2110

Query: 456  REMPGV 461
            ++  G+
Sbjct: 2111 QKAEGI 2116



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 60/247 (24%), Positives = 102/247 (41%), Gaps = 26/247 (10%)

Query: 157  PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCPEDI- 214
            P+ +   +       + +     P  D  + PE  EEA E   +  E + +  P  ED+ 
Sbjct: 2027 PKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVD 2086

Query: 215  AKEKRTPA-PEPEPCEASELP--AKRLRSSEEPTEKEPPGQLQVKAQPQAR-MTVPKQTQ 270
            A+E    A PE E  EA E    A++    E P       + + +AQP++  +  P+   
Sbjct: 2087 AQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAP-------ETEGEAQPESEGIEAPEAEG 2139

Query: 271  TPDLLPEALEAQVLP-RFQPRVLQVQAQ-VQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 328
                  E +EAQ      QP    ++AQ  + + QP +   +         +A+ +  PE
Sbjct: 2140 EAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAP-------EAEGEAQPE 2192

Query: 329  HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQ--THEQPH 386
               ++  + + + Q E E  +   P+   +AQP  +  E P A+   QP  +  T  +  
Sbjct: 2193 SEGIEAPEAEGEAQPELEGVEA--PEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250

Query: 387  TQPQVSL 393
              PQVSL
Sbjct: 2251 GSPQVSL 2257



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 87/440 (19%), Positives = 159/440 (36%), Gaps = 65/440 (14%)

Query: 158  QKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE--DQDLPPCPEDIA 215
            + Q  +    TP   ++  +  P  + ++ PE  +EA +P  ++ E  + +    PE   
Sbjct: 1882 EAQPESEDVETP---EAEWEVQPESEGAEAPEAEKEA-QPETESVEALETEGEDEPESEG 1937

Query: 216  KEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLL 275
             E +      +  E    P   +  S+E  E+  P    V+A     + V  Q    +  
Sbjct: 1938 AEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEA---LEVEVETQEAEGEAQ 1994

Query: 276  PEALEAQVLPRFQPRVLQVQAQVQSQT-----QPRIPSTDTQVQPKLQKQAQTQTSPEHL 330
            PE+ + +  P  +  + + + + Q ++     QP+    + Q      ++ +    PE  
Sbjct: 1995 PESEDVEA-PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESD 2053

Query: 331  VLQQKQVQPQLQQEAEPQKQVQPQVHT------------QAQPSVQPQEHPPAQVSVQPP 378
             ++  + + + Q+     ++ + + H             +AQP  +  E P A+   Q  
Sbjct: 2054 GVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKA 2113

Query: 379  EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA--VEAGGGMEKTLPEPVG--TQVS 434
            E   E P T+ +     PE   +       E  P++  VEA     +  PE  G   Q +
Sbjct: 2114 EGI-EAPETEGEAQ---PESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEA 2169

Query: 435  MEEIQNESACGLDVGECENRAR-EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPS 493
             EE Q E   G++  E E  A+ E  G+              ++  A   +     P   
Sbjct: 2170 EEEAQPELE-GVEAPEAEGEAQPESEGIEA----------PEAEGEAQPELEGVEAPEAE 2218

Query: 494  DSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQ-DHMSEPQHQQRLGEIQHMSQACL 552
            +     P    TP  +         +A   S+ E Q +    PQ     G+ +  S+   
Sbjct: 2219 EEAQPEPEGVETPEAEG--------EAQPESEGETQGEKKGSPQVSLGDGQSEEASE--- 2267

Query: 553  LSLLPVPRDVLETEDEEPPP 572
             S  PVP D        PPP
Sbjct: 2268 -SSSPVPED-----RPTPPP 2281



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 14/89 (15%)

Query: 621  VEHVKSQGHKD------KAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEE 674
            VE ++++G  +      +A+E +   +E  GQ +     +++    E +EE + + ED E
Sbjct: 1922 VEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ---EAEEEAQPESEDVE 1978

Query: 675  EIEVEEELCK-----QVRSRDISREEWKG 698
             +EVE E  +     Q  S D+   E +G
Sbjct: 1979 ALEVEVETQEAEGEAQPESEDVEAPEAEG 2007


>gi|58530845 zyxin [Homo sapiens]
          Length = 572

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 69/298 (23%), Positives = 109/298 (36%), Gaps = 26/298 (8%)

Query: 108 LAAPSLTPPQLATPNLQQFF-PQATRQSLLGPPPVGVPMNPSQFN---LSGRNPQKQART 163
           +AAP  +P    + +   F+ PQ     ++ P P   P  P         G    +  R 
Sbjct: 1   MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 60

Query: 164 SSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 223
                P  +D      P+    D  EG+   A P    P ++  PP P    +E+  P+P
Sbjct: 61  GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAP---LEEEIFPSP 117

Query: 224 EPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV 283
            P P E    P   +    +P EK     L++ +       + K         +  +A+V
Sbjct: 118 PPPPEEEGG-PEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKN--------DPFKARV 168

Query: 284 LPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 343
              + P  +      +S T+P   +  T   P  +  + +Q  P        QV    Q 
Sbjct: 169 SSGYVPPPVATPFSSKSSTKPA--AGGTAPLPPWKSPSSSQPLP--------QVPAPAQS 218

Query: 344 EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 401
           + +   Q QPQ   Q Q  VQ Q  P +  + QP       P   P+ S + P+ TPV
Sbjct: 219 QTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPV 276


>gi|4508047 zyxin [Homo sapiens]
          Length = 572

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 69/298 (23%), Positives = 109/298 (36%), Gaps = 26/298 (8%)

Query: 108 LAAPSLTPPQLATPNLQQFF-PQATRQSLLGPPPVGVPMNPSQFN---LSGRNPQKQART 163
           +AAP  +P    + +   F+ PQ     ++ P P   P  P         G    +  R 
Sbjct: 1   MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 60

Query: 164 SSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 223
                P  +D      P+    D  EG+   A P    P ++  PP P    +E+  P+P
Sbjct: 61  GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAP---LEEEIFPSP 117

Query: 224 EPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV 283
            P P E    P   +    +P EK     L++ +       + K         +  +A+V
Sbjct: 118 PPPPEEEGG-PEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKN--------DPFKARV 168

Query: 284 LPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 343
              + P  +      +S T+P   +  T   P  +  + +Q  P        QV    Q 
Sbjct: 169 SSGYVPPPVATPFSSKSSTKPA--AGGTAPLPPWKSPSSSQPLP--------QVPAPAQS 218

Query: 344 EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 401
           + +   Q QPQ   Q Q  VQ Q  P +  + QP       P   P+ S + P+ TPV
Sbjct: 219 QTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPV 276


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 103/421 (24%), Positives = 146/421 (34%), Gaps = 59/421 (14%)

Query: 111  PSLTPPQ-LATPNLQQFFPQA-----TRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 164
            P++TPP    TP L    P +     T  S  GP P      PS        P    R  
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA--TPSHKGGPAMTPPSPKRGP 1393

Query: 165  SSTTPNRKDSSSQTMPVEDKSDP--PEGSEEAAEPRMDTPEDQDLPP---CPEDIAKEKR 219
            +  +P    +S   +P+  K  P  P   E AA     TP   DL P    P  + K   
Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA-----TPSKGDLTPPAVTPVSLKKAPA 1448

Query: 220  TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL 279
            T AP+  P   S      L +   P+ KEPP   QV     A  + PK+       P  +
Sbjct: 1449 TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV-----ATSSSPKKAPA---TPAPM 1500

Query: 280  EAQVLPRFQP-RVLQVQAQVQSQTQPRIPS-------TDTQVQPK--LQKQAQTQTSPEH 329
             A  LP   P    +V A   S+  P  P+       T   + PK  L   A T  SP+ 
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560

Query: 330  ---LVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 386
               +   ++       +EA     V P  +  A PS +    PPA  S  P E       
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA-PSPKELLIPPAVTSPSPKEAP----- 1614

Query: 387  TQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGL 446
            T P V+  +PE+ P      G    P    +      T P  V  ++     Q       
Sbjct: 1615 TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ------- 1667

Query: 447  DVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTP 506
                    ++ +P   G     +V +  + +S    T P    P+   S +++P     P
Sbjct: 1668 -------ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP 1720

Query: 507  S 507
            S
Sbjct: 1721 S 1721



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 87/388 (22%), Positives = 136/388 (35%), Gaps = 42/388 (10%)

Query: 33   QQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTN---SASLLNGSMLQRAL 89
            ++LL    +   SP +AP P AV+   P + P  P      T+   + S L  S    A 
Sbjct: 1597 KELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656

Query: 90   LLQQLQGNLRGYGMASPGLAAPS------LTPPQLATPNLQ---QFFPQATRQSLLGPPP 140
            +  ++   +       P    P+      + P   +TP +    +  PQ  + S   PP 
Sbjct: 1657 VTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP- 1715

Query: 141  VGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMD 200
              +  +PS  N  G          +   P +KDSS +T   +D S  P+G     E +  
Sbjct: 1716 --ICPDPSAKN--GSKGPLSTVAPAPLLPVQKDSS-KTAKGKDASHSPKGPLAPPESKAS 1770

Query: 201  TPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQ 260
            TP            A EK  P PE     A+  P   L  +  P    PP Q  + + P 
Sbjct: 1771 TPLTA--------AAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPG 1822

Query: 261  ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS--QTQPRIPSTDTQVQPKLQ 318
              +  P +   P     A E ++LP   P  +      QS     P   S    V     
Sbjct: 1823 LVLESPSKPLAP-----ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSA 1877

Query: 319  KQAQTQTSP-EHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP 377
            KQ  T+ +          +  P+L+++   Q   Q     Q   + +  E P     V  
Sbjct: 1878 KQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQ---QAQLAAAAEIDEEP-----VSK 1929

Query: 378  PEQTHEQPHTQPQVSLLAPEQTPVVVHV 405
             +Q+  +   +  +S L   Q   V  V
Sbjct: 1930 AKQSRSEKKARKAMSKLGLRQVTGVTRV 1957



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 53/236 (22%), Positives = 73/236 (30%), Gaps = 24/236 (10%)

Query: 45   SPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRG---Y 101
            SP   PLP        P  P   L + +G  +   L G+    A      +G        
Sbjct: 1046 SPAATPLPKGA-----PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100

Query: 102  GMASPGLAAPS------LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR 155
            G   P  A P        TPP    P      P + +  L  PPP G P  P+    S +
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160

Query: 156  N-----PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPC 210
                  P K A T+ + TP        T   +     P  +  + +  + TP  +  P  
Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220

Query: 211  PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP 266
            P       +     P P  A   PA     +  P+ K  P     K  P      P
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPA-----ATPPSPKGGPATPPPKGAPTPPAATP 1271



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 92/440 (20%), Positives = 143/440 (32%), Gaps = 39/440 (8%)

Query: 102  GMASP----GLAAPSLTPPQ----LATPNLQ------QFFPQATRQSLLGPPPVGVPMNP 147
            G+A+P        P+ TPP     LATP+ +         P + +  L  P P G P  P
Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221

Query: 148  SQFNLSGRN-----PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTP 202
            +    S +        K A T+ + TP        T P +    PP  +  + +  + TP
Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281

Query: 203  EDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP-QA 261
              +  P  P  +      P+P+  P  +    A    ++  P+ K  PG    K  P   
Sbjct: 1282 PHKGAPN-PAVVT----PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336

Query: 262  RMTVPKQTQTPDL---LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ 318
             +T P    TP L    P +      P  +       A    +  P +     +  P + 
Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396

Query: 319  KQAQTQTSPEHLVLQQKQVQP---QLQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVS 374
                  TSP  + L  K+        +  A P K  + P   T       P    P    
Sbjct: 1397 SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP---K 1453

Query: 375  VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGM-EKTLPEPVGTQV 433
              P   + +   T P V+  +P++ P    V     P  A      M   TLP  + +  
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513

Query: 434  SMEEIQNESACGLDVGECENRAREMPGVWGAGGSL---KVTILQSSDSRAFSTVPLTPVP 490
                    S            +++ P       +L    +T+     + A  T    P  
Sbjct: 1514 KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT 1573

Query: 491  RPSDSVSSTPAATSTPSKQA 510
              S   SS PA T +  K A
Sbjct: 1574 PSSKEASSPPAVTPSTYKGA 1593



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 73/334 (21%), Positives = 100/334 (29%), Gaps = 67/334 (20%)

Query: 138  PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPP-----EGSE 192
            P P+GV ++P     + R P K+      T     + SS   PVE    P      +GS+
Sbjct: 794  PSPLGVSVSPQ----TKRPPTKKGSAGPDTPIG--NLSSPVSPVEASFLPENSLSFQGSK 847

Query: 193  EA-AEPRMDTPEDQDLPPCPEDIAK---------EKRTPAPE----PEPCEASELPAKR- 237
            ++ A     TP      P P  +            K TP P     P P E    PA + 
Sbjct: 848  DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907

Query: 238  -----LRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 292
                 + SS     +  P    + A P      PK   TP   P A      P+  P   
Sbjct: 908  APALSMTSSSPKKARATPAPKGIPASPS-----PKGAPTP---PAATPPS--PKGGP--- 954

Query: 293  QVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQ---QEAEPQK 349
                   +   P+   T     P   K      SP+          P  +       P+ 
Sbjct: 955  -------ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007

Query: 350  QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH-------------TQPQVSLLAP 396
               P   T   P   P   P  + +  PP  T   P              T P  +L +P
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067

Query: 397  EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVG 430
            +  P    + G   PP A           P P G
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 77/368 (20%), Positives = 109/368 (29%), Gaps = 60/368 (16%)

Query: 45   SPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMA 104
            SP  AP P AV+    P  P+   L  + T + S++N                       
Sbjct: 860  SPKGAPTPSAVT----PLSPKGVTLPPKETPTPSVVN-------------------LPFP 896

Query: 105  SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 164
              G A P+  P Q    ++    P+  R +   P P G+P +PS          K A T 
Sbjct: 897  KEGPATPA--PKQAPALSMTSSSPKKARAT---PAPKGIPASPSP---------KGAPTP 942

Query: 165  SSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPE 224
             + TP        T   +    PP  +  + +    TP  +  P  P       +     
Sbjct: 943  PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT 1002

Query: 225  PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL 284
            P P  A   PA         T   P G       P+   T P    TP     +  A  L
Sbjct: 1003 PSPKGAPTPPA--------VTPPSPKGSPAATPFPKGASTPP--AATPPSPKGSPAATPL 1052

Query: 285  PRFQPRVLQVQAQVQSQTQPRIPS-----TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 339
            P+  P           +  P  PS     T     P   K      SP+   +      P
Sbjct: 1053 PKGAP-TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111

Query: 340  QLQQE-AEPQKQVQPQVHTQAQPS------VQPQEHPPAQVSVQPPEQTHEQPHTQPQVS 392
              +   A P  +  P       PS        P +  P   +  PP          P+ +
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA 1171

Query: 393  LLAPEQTP 400
               P  TP
Sbjct: 1172 PTTPAATP 1179



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 61/286 (21%), Positives = 86/286 (30%), Gaps = 27/286 (9%)

Query: 143  VPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSS--SQTMPVEDKSD--PPEGSEEAAEPR 198
            +P N   F  S  +P   A T S T P+ K +   S   P+  K    PP+ +   +   
Sbjct: 836  LPENSLSFQGSKDSP---ATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN 892

Query: 199  MDTPEDQDLPPCPEDIA----------KEKRTPAPEPEPCEASELPAKRLRSSEEPTEKE 248
            +  P++    P P+             K + TPAP+  P   S   A    ++  P+ K 
Sbjct: 893  LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952

Query: 249  PPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS 308
             P     K  P      P   +     P    A   P   P   +      S      P 
Sbjct: 953  GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012

Query: 309  TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEH 368
              T   PK    A                 P+    A P  +  P       PS  P+  
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS--PKGG 1070

Query: 369  PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA 414
            P        P        T P  +  +P+  P      G  MPP A
Sbjct: 1071 PATPSLKGAP--------TPPAATPPSPKGGPATPSPKGAPMPPAA 1108


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,470,244
Number of Sequences: 37866
Number of extensions: 2365462
Number of successful extensions: 45779
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 535
Number of HSP's successfully gapped in prelim test: 1081
Number of HSP's that attempted gapping in prelim test: 19657
Number of HSP's gapped (non-prelim): 13368
length of query: 818
length of database: 18,247,518
effective HSP length: 111
effective length of query: 707
effective length of database: 14,044,392
effective search space: 9929385144
effective search space used: 9929385144
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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