BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 [Homo sapiens] (818 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ... 1659 0.0 gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ... 1645 0.0 gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ... 1630 0.0 gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ... 1615 0.0 gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [... 1615 0.0 gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 83 1e-15 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 81 4e-15 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 79 2e-14 gi|56549696 E1A binding protein p400 [Homo sapiens] 79 2e-14 gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 75 2e-13 gi|38788274 bromodomain PHD finger transcription factor isoform ... 72 2e-12 gi|146134388 YLP motif containing 1 [Homo sapiens] 69 2e-11 gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 67 7e-11 gi|119943102 CREB binding protein isoform b [Homo sapiens] 67 9e-11 gi|119943104 CREB binding protein isoform a [Homo sapiens] 67 9e-11 gi|17017963 forkhead box P2 isoform I [Homo sapiens] 66 1e-10 gi|22538413 forkhead box P2 isoform III [Homo sapiens] 66 1e-10 gi|149999352 forkhead box P2 isoform II [Homo sapiens] 66 1e-10 gi|38788260 bromodomain PHD finger transcription factor isoform ... 66 1e-10 gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 65 2e-10 gi|221139761 zinc finger protein 853 [Homo sapiens] 64 6e-10 gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 64 6e-10 gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 64 6e-10 gi|110349719 titin isoform N2-A [Homo sapiens] 64 7e-10 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 63 1e-09 gi|197276594 RNA binding motif protein 20 [Homo sapiens] 63 1e-09 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 63 1e-09 gi|58530845 zyxin [Homo sapiens] 62 2e-09 gi|4508047 zyxin [Homo sapiens] 62 2e-09 gi|163965366 nascent polypeptide-associated complex alpha subuni... 62 2e-09 >gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 [Homo sapiens] Length = 818 Score = 1659 bits (4295), Expect = 0.0 Identities = 818/818 (100%), Positives = 818/818 (100%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLAT 120 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLAT Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLAT 120 Query: 121 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 180 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP Sbjct: 121 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 180 Query: 181 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 240 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS Sbjct: 181 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 240 Query: 241 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 300 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS Sbjct: 241 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 300 Query: 301 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 360 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ Sbjct: 301 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 360 Query: 361 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGG 420 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGG Sbjct: 361 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGG 420 Query: 421 MEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRA 480 MEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRA Sbjct: 421 MEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRA 480 Query: 481 FSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQR 540 FSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQR Sbjct: 481 FSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQR 540 Query: 541 LGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAK 600 LGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAK Sbjct: 541 LGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAK 600 Query: 601 QSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCF 660 QSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCF Sbjct: 601 QSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCF 660 Query: 661 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDFLVPVMGYI 720 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDFLVPVMGYI Sbjct: 661 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDFLVPVMGYI 720 Query: 721 CRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTTRPVSRRCAINARNALTALF 780 CRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTTRPVSRRCAINARNALTALF Sbjct: 721 CRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTTRPVSRRCAINARNALTALF 780 Query: 781 TSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 818 TSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT Sbjct: 781 TSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 818 >gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 [Homo sapiens] Length = 842 Score = 1645 bits (4260), Expect = 0.0 Identities = 818/842 (97%), Positives = 818/842 (97%), Gaps = 24/842 (2%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 Query: 97 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 Query: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240 Query: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300 Query: 277 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360 Query: 337 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 396 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP Sbjct: 361 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 420 Query: 397 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 456 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR Sbjct: 421 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 480 Query: 457 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 516 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY Sbjct: 481 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 540 Query: 517 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 576 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC Sbjct: 541 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 600 Query: 577 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 636 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL Sbjct: 601 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 660 Query: 637 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 696 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW Sbjct: 661 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 720 Query: 697 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 756 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN Sbjct: 721 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 780 Query: 757 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 816 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL Sbjct: 781 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 840 Query: 817 KT 818 KT Sbjct: 841 KT 842 >gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 [Homo sapiens] Length = 837 Score = 1630 bits (4221), Expect = 0.0 Identities = 813/842 (96%), Positives = 813/842 (96%), Gaps = 29/842 (3%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 Query: 97 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 Query: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216 PQKQARTSSSTTPNRK TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK Sbjct: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235 Query: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP Sbjct: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295 Query: 277 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ Sbjct: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355 Query: 337 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 396 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP Sbjct: 356 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 415 Query: 397 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 456 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR Sbjct: 416 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 475 Query: 457 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 516 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY Sbjct: 476 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 535 Query: 517 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 576 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC Sbjct: 536 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 595 Query: 577 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 636 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL Sbjct: 596 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 655 Query: 637 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 696 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW Sbjct: 656 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 715 Query: 697 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 756 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN Sbjct: 716 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 775 Query: 757 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 816 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL Sbjct: 776 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 835 Query: 817 KT 818 KT Sbjct: 836 KT 837 >gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo sapiens] Length = 898 Score = 1615 bits (4182), Expect = 0.0 Identities = 818/898 (91%), Positives = 818/898 (91%), Gaps = 80/898 (8%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 Query: 97 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 Query: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240 Query: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300 Query: 277 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360 Query: 337 VQPQLQQEAEPQ------------------------------------------------ 348 VQPQLQQEAEPQ Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420 Query: 349 ----KQVQ----PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 400 KQVQ PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480 Query: 401 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 460 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540 Query: 461 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 520 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600 Query: 521 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 580 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660 Query: 581 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 640 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720 Query: 641 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 700 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780 Query: 701 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 760 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840 Query: 761 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 818 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898 >gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo sapiens] Length = 898 Score = 1615 bits (4182), Expect = 0.0 Identities = 818/898 (91%), Positives = 818/898 (91%), Gaps = 80/898 (8%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 Query: 97 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 Query: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240 Query: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300 Query: 277 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360 Query: 337 VQPQLQQEAEPQ------------------------------------------------ 348 VQPQLQQEAEPQ Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420 Query: 349 ----KQVQ----PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 400 KQVQ PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480 Query: 401 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 460 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540 Query: 461 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 520 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600 Query: 521 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 580 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660 Query: 581 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 640 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720 Query: 641 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 700 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780 Query: 701 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 760 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840 Query: 761 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 818 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898 >gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] Length = 788 Score = 82.8 bits (203), Expect = 1e-15 Identities = 92/320 (28%), Positives = 132/320 (41%), Gaps = 67/320 (20%) Query: 5 QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54 Q QQQ+QQQQQQLQ++ QQQQ QQQQ QQQQ LQ Q +QQ P PQ P A Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285 Query: 55 VSRGL----------PPQQPQQPLLNLQG-------------TNSASLLNGSML------ 85 + + L PP QPQQP + + A L G ML Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPL 345 Query: 86 ---QRALLLQQ--LQGNLRGYGMASPGLAAPSLTPP--QLATPNLQQFFPQATRQSLLGP 138 + +++QQ +Q ++ A A + P Q+ T L Q + P Sbjct: 346 KFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARF---P 402 Query: 139 PPVGVPMNPSQFNLSGRNPQKQARTS-----SSTTPNRKDSSSQTMPVEDKSDPPEGSEE 193 P V PS GR P Q S SS +P ++ + Q+MP PP+ S + Sbjct: 403 PTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMP-----PPPQPSPQ 457 Query: 194 AAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL 253 +P + P P + P+P P+P + S + A+ ++ P+ PG L Sbjct: 458 PGQPSSQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS----PGPL 509 Query: 254 QVKAQPQARMTVPKQTQTPD 273 P + M+ +Q + Sbjct: 510 NTPVNPSSVMSPAGSSQAEE 529 Score = 69.7 bits (169), Expect = 1e-11 Identities = 104/408 (25%), Positives = 139/408 (34%), Gaps = 87/408 (21%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63 QQQQQQ QQQQQ Q QQQQ QQQQ Q QQ QQ Q L QQ Sbjct: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ-------QQQ 215 Query: 64 PQQPLLNLQGTNSASL-LNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPN 122 QQ L+ L N + LQR LQ Q + A PP + P Sbjct: 216 QQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPP-IQQPP 274 Query: 123 LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN---PQKQARTSSSTTPNRKDSSSQTM 179 +QQ P PP +P Q + + + PQ Q + P++ SQT Sbjct: 275 MQQPQP---------PPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325 Query: 180 PVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLR 239 P+ ++ G +P P K +R Sbjct: 326 PLVSQAQALPGQMLYTQP------------------------------------PLKFVR 349 Query: 240 SSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQ 299 + ++PP Q QV+ Q A T A AQ++ + + AQ Sbjct: 350 A--PMVVQQPPVQPQVQQQQTAVQT-------------AQAAQMVAPGVQMITEALAQGG 394 Query: 300 SQTQPRIPSTDT-----QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQ 354 + R P T L +Q Q S L + P Q+ + + + P Sbjct: 395 MHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLS---SPSPGQQVQTPQSMPPP 451 Query: 355 VHTQAQPSVQPQEHPPAQVSVQP-PEQTHEQPHTQPQVSLLAPEQTPV 401 QP QP P + VS P P + P PQ P Q+PV Sbjct: 452 PQPSPQPG-QPSSQPNSNVSSGPAPSPSSFLPSPSPQ-----PSQSPV 493 Score = 63.9 bits (154), Expect = 6e-10 Identities = 57/195 (29%), Positives = 90/195 (46%), Gaps = 11/195 (5%) Query: 222 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 281 AP ++ P +L+ + +++ Q Q + Q QA + +Q Q +A ++ Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194 Query: 282 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 340 + +FQ V Q Q Q Q Q Q + Q Q ++Q+Q Q L LQQ+Q Q Q Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254 Query: 341 LQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 399 QQ+ + Q Q QP + QP +Q + PP+Q Q +Q H H QP P+Q Sbjct: 255 QQQQQQQQALQAQPPIQ---QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQP 308 Query: 400 PVVVHVCGLEMPPDA 414 PV + ++PP + Sbjct: 309 PVAQNQPS-QLPPQS 322 Score = 53.1 bits (126), Expect = 1e-06 Identities = 67/272 (24%), Positives = 100/272 (36%), Gaps = 30/272 (11%) Query: 128 PQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP 187 P QSL G P G + + R P + S + P+ P Sbjct: 81 PMNALQSLTGGPAAGA----AGIGMPPRGPGQSLGGMGSL-------GAMGQPMSLSGQP 129 Query: 188 PEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEK 247 P G+ A M P+ + ++ + + + + + ++ ++ Sbjct: 130 PPGTSGMAPHSMAVVSTAT----PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ 185 Query: 248 EPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIP 307 + Q Q A Q V +Q Q L + + Q L + Q Q Q+Q Q Q Sbjct: 186 QQQFQAQQSAMQQQFQAVVQQQQ--QLQQQQQQQQHLIKLHH---QNQQQIQQQQQQLQR 240 Query: 308 STDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ-PQLQQEAEPQKQVQPQV-----HTQ-AQ 360 Q+Q + Q+Q Q Q + + Q +Q P +QQ P Q PQ HTQ Q Sbjct: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300 Query: 361 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVS 392 P QPQ+ P AQ P Q Q TQP VS Sbjct: 301 PPPQPQQPPVAQ---NQPSQLPPQSQTQPLVS 329 Score = 42.7 bits (99), Expect = 0.001 Identities = 79/365 (21%), Positives = 128/365 (35%), Gaps = 62/365 (16%) Query: 91 LQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQF 150 LQ L G G + G+ P P Q + + SL G PP G Sbjct: 85 LQSLTG---GPAAGAAGIGMPPRGPGQ-SLGGMGSLGAMGQPMSLSGQPPPGT------- 133 Query: 151 NLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPC 210 SG P A S++T + + + + + ++AA + + Q Sbjct: 134 --SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQA 191 Query: 211 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ 270 + +++ ++ ++ +++ Q +K Q + + +Q Q Sbjct: 192 QQSAMQQQFQAV---------------VQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQ 236 Query: 271 TPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHL 330 + + L+ Q + Q Q Q Q Q Q + + QP +Q Q Q P Sbjct: 237 QLQRIAQ-LQLQ-------QQQQQQQQQQQQQQQALQAQPPIQQPPMQ---QPQPPPSQA 285 Query: 331 VLQQKQVQPQLQQEAEPQKQVQPQV----------HTQAQPSV-QPQEHPPAQVSVQPP- 378 + QQ Q Q P + QP V +Q QP V Q Q P + QPP Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPL 345 Query: 379 ---------EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPV 429 +Q QP Q Q + + Q +V G++M +A+ A GGM P Sbjct: 346 KFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV-APGVQMITEAL-AQGGMHIRARFPP 403 Query: 430 GTQVS 434 T VS Sbjct: 404 TTAVS 408 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 80.9 bits (198), Expect = 4e-15 Identities = 85/291 (29%), Positives = 123/291 (42%), Gaps = 49/291 (16%) Query: 5 QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54 Q QQQ+QQQQQQLQ++ QQQQ QQQQ QQQQ LQ Q +QQ P PQ P A Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285 Query: 55 VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGNLRGYG 102 + + L PP QPQQP + N S L + L+ Q L G + Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342 Query: 103 MASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQAR 162 + AP + P +QQ Q Q+ V + SQ +L Sbjct: 343 PPLKFVRAPMVVQQPPVQPQVQQ--QQTAVQTAQAAQMVAPGVQVSQSSLP--------- 391 Query: 163 TSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPA 222 SS +P ++ + Q+MP PP+ S + +P + P P + P+ Sbjct: 392 MLSSPSPGQQVQTPQSMP-----PPPQPSPQPGQPSSQPNSNVSSGPAP---SPSSFLPS 443 Query: 223 PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPD 273 P P+P + S + A+ ++ P+ PG L P + M+ +Q + Sbjct: 444 PSPQPSQ-SPVTARTPQNFSVPS----PGPLNTPVNPSSVMSPAGSSQAEE 489 Score = 68.6 bits (166), Expect = 2e-11 Identities = 85/329 (25%), Positives = 113/329 (34%), Gaps = 42/329 (12%) Query: 2 FSQQQQQQLQQQQQQLQQ------------------LQQQQLQQQQLQQQQLLQLQQLLQ 43 F QQQQ LQQQQQQ QQ QQQQLQQQQ QQQ L++L Q Sbjct: 169 FQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQ 228 Query: 44 QSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQR-----------ALLLQ 92 Q Q + L QQ QQ Q +L +Q+ L Q Sbjct: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQ 288 Query: 93 QLQGNLRGYGMASP--------GLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVP 144 QLQ P PS PPQ T L Q L PP+ Sbjct: 289 QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFV 348 Query: 145 MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP----PEGSEEAAEPRMD 200 P PQ Q + ++ T + + V S P P ++ P+ Sbjct: 349 RAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSM 408 Query: 201 TPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQ 260 P Q P + ++ + P P +S LP+ + S+ P P V + Sbjct: 409 PPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGP 468 Query: 261 ARMTV-PKQTQTPDLLPEALEAQVLPRFQ 288 V P +P +A E Q L + + Sbjct: 469 LNTPVNPSSVMSPAGSSQAEEQQYLDKLK 497 Score = 68.2 bits (165), Expect = 3e-11 Identities = 93/365 (25%), Positives = 129/365 (35%), Gaps = 47/365 (12%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63 QQQQQQ QQQQQ Q QQQQ QQQQ Q QQ QQ Q L QQ Sbjct: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ-------QQQ 215 Query: 64 PQQPLLNLQGTNSASL-LNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPN 122 QQ L+ L N + LQR LQ Q + A PP + P Sbjct: 216 QQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPP-IQQPP 274 Query: 123 LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN---PQKQARTSSSTTPNRKDSSSQTM 179 +QQ P PP +P Q + + + PQ Q + P++ SQT Sbjct: 275 MQQPQP---------PPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325 Query: 180 PVEDKSDPPEGSEEAAEPRMD---TPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAK 236 P+ ++ G +P + P PP + +++ A + P Sbjct: 326 PLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV--QQQQTAVQTAQAAQMVAPGV 383 Query: 237 RLRSSEEPTEKEP-PGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQ 295 ++ S P P PGQ Q QTP +P + P QP Q Sbjct: 384 QVSQSSLPMLSSPSPGQ---------------QVQTPQSMPPPPQPSPQPG-QPS-SQPN 426 Query: 296 AQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQV 355 + V S P S P+ + T +P++ + L P + P Sbjct: 427 SNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPS---PGPLNTPVNPSSVMSPAG 483 Query: 356 HTQAQ 360 +QA+ Sbjct: 484 SSQAE 488 Score = 64.7 bits (156), Expect = 3e-10 Identities = 88/333 (26%), Positives = 135/333 (40%), Gaps = 61/333 (18%) Query: 222 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 281 AP ++ P +L+ + +++ Q Q + Q QA + +Q Q +A ++ Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194 Query: 282 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 340 + +FQ V Q Q Q Q Q Q + Q Q ++Q+Q Q L LQQ+Q Q Q Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254 Query: 341 LQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 399 QQ+ + Q Q QP + QP +Q + PP+Q Q +Q H H QP P+Q Sbjct: 255 QQQQQQQQALQAQPPIQ---QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQP 308 Query: 400 PVVVHVCGLEMPP---------DAVEAGGGMEKTLP-------------EPVGTQVSMEE 437 PV + ++PP A G M T P PV QV ++ Sbjct: 309 PVAQNQPS-QLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367 Query: 438 IQNESACGLDVGECENRAREM--PGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPS-- 493 ++A +A +M PGV + SL + S + + + P P+PS Sbjct: 368 TAVQTA----------QAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ 417 Query: 494 ---------DSVSSTPAAT-----STPSKQALQ 512 +VSS PA + +PS Q Q Sbjct: 418 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ 450 Score = 31.6 bits (70), Expect = 3.1 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 12/91 (13%) Query: 307 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE---------AEPQKQVQPQVHT 357 P + + P T T L LQQ +Q Q QQ+ + Q+Q Q Q Sbjct: 130 PPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQF 189 Query: 358 QAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 388 QAQ S Q+ Q VQ +Q +Q Q Sbjct: 190 QAQQSAMQQQF---QAVVQQQQQLQQQQQQQ 217 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 78.6 bits (192), Expect = 2e-14 Identities = 120/425 (28%), Positives = 151/425 (35%), Gaps = 45/425 (10%) Query: 4 QQQQQQLQQQQQQLQQLQQQQL-QQQQLQQQQL--LQLQQLLQQSPPQAPLPMAVSRGLP 60 Q QQQQ QQQQQLQQ QQQQL QQQQLQQQQL Q QQ LQQ Q Sbjct: 3899 QLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQ 3958 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGM--------ASPGLAAPS 112 QQ QQ Q LLN S + QQ Q G GM +SPG P+ Sbjct: 3959 QQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPT 4018 Query: 113 LTPPQLATPNLQQFFPQATRQSLLGPPP-VGVPMNPSQFNLSGRNPQKQARTSSSTTPNR 171 L L P + ++ GP G P+ G P+ A P+ Sbjct: 4019 LL---LTGKEQNTVDPAVSSEATEGPSTHQGGPL------AIGTTPESMATEPGEVKPS- 4068 Query: 172 KDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEAS 231 SQ + V+ + P S + P + Q EAS Sbjct: 4069 LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEAS 4128 Query: 232 ELPAKRLRSSEEPTEKEPPGQLQVK----AQPQARMTVPKQT--QTPDLLPEALEAQVLP 285 +P L + + + PG + QP + T Q P P Q LP Sbjct: 4129 SVP--HLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLP 4186 Query: 286 --RFQPRVLQVQAQVQS--QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL 341 P V Q++AQ+Q P++ Q Q +LQ + LQQ Q Q Sbjct: 4187 GVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQ------LQQSQAVRQT 4240 Query: 342 QQEAEPQKQVQP-QVHTQAQPSV----QPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 396 EP Q P Q QP + PQ P ++ P Q + P P Sbjct: 4241 PPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGP 4300 Query: 397 EQTPV 401 PV Sbjct: 4301 VLGPV 4305 Score = 75.5 bits (184), Expect = 2e-13 Identities = 110/438 (25%), Positives = 163/438 (37%), Gaps = 71/438 (16%) Query: 4 QQQQQQLQQQQQQ----LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAP-----LPMA 54 Q+Q Q+++QQ++ + + + +Q QQQQ QQQQ Q +L SP Q+P LP Sbjct: 3575 QKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQ 3634 Query: 55 VSRGLPPQQPQQP--------LLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYG-MAS 105 + G Q PQ P L G G L AL QQ Q + G G +A Sbjct: 3635 LLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAG 3694 Query: 106 PG-------LAAPSLTPP----------------QLATPNLQQFFPQATRQSLLGPPPVG 142 P LA SL P QLA QQ Q +Q LLG + Sbjct: 3695 PSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAI- 3753 Query: 143 VPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKS-DPPEGSEEAAEPRMDT 201 Q G Q SS Q + V+ S PP+G + Sbjct: 3754 -----QQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGM------- 3801 Query: 202 PEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQA 261 L P + +++ A P+ P +++ ++ P Q + Sbjct: 3802 -----LGPAQVAVLQQQHPGALGPQG------PHRQVLMTQSRVLSSPQLAQQGQGLMGH 3850 Query: 262 RMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA 321 R+ +Q Q + L Q ++ Q + QP Q Q +LQ+Q Sbjct: 3851 RLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQ 3910 Query: 322 QTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQT 381 Q Q + + QQ+Q+Q Q Q+ + Q+Q+Q Q Q Q Q+ Q Q +Q Sbjct: 3911 QLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ-----QQQQQLQQQQQQQQQQ 3965 Query: 382 HEQPHTQPQVSLLAPEQT 399 +Q Q Q+ LL +T Sbjct: 3966 FQQQQQQQQMGLLNQSRT 3983 Score = 63.2 bits (152), Expect = 1e-09 Identities = 98/423 (23%), Positives = 148/423 (34%), Gaps = 81/423 (19%) Query: 4 QQQQQQLQQQQQQL-QQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62 Q++Q QLQQQ+ QL Q+LQQQ QQQ QQQQ L Q +QQ Q P P Sbjct: 3717 QERQLQLQQQRMQLAQKLQQQ---QQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP 3773 Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPN 122 Q P + QG LL+QQL S PPQ Sbjct: 3774 QGLMPPSSHQG---------------LLVQQL-----------------SPQPPQ----- 3796 Query: 123 LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVE 182 Q +LGP V V L + P +Q + S + + Q + Sbjct: 3797 --------GPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLM 3848 Query: 183 DKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC-EASELPAKRLRSS 241 ++ + L + + P +P +L ++ Sbjct: 3849 GHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQ 3908 Query: 242 EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 301 ++ +++ QLQ + Q Q + +Q Q + L+ Q + Q + Q+Q Q Q Q Sbjct: 3909 QQQLQQQQQQQLQQQQQLQQQQLQQQQQQ------QQLQQQQQQQLQQQQQQLQQQ-QQQ 3961 Query: 302 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP-----QLQQEAEP--------- 347 Q + Q Q L Q++T SP+ QQ + P LQ + P Sbjct: 3962 QQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLL 4021 Query: 348 ----QKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVS------LLAPE 397 Q V P V ++A + P + P E +P +S L+ P+ Sbjct: 4022 TGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQ 4081 Query: 398 QTP 400 P Sbjct: 4082 PQP 4084 Score = 62.4 bits (150), Expect = 2e-09 Identities = 84/302 (27%), Positives = 117/302 (38%), Gaps = 41/302 (13%) Query: 106 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 165 P L+PP +P P+A+R L PPP PM+P P + +R S Sbjct: 601 PPFEESPLSPPPEESPLSPP--PEASR---LSPPPEDSPMSPPPEESPMSPPPEVSRLSP 655 Query: 166 STTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEP 225 +R + P+ S PPE S P PE L P PED +P P Sbjct: 656 LPVVSRLSPPPEESPL---SPPPEES-----PTSPPPEASRLSPPPED-----SPTSPPP 702 Query: 226 EPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 285 E AS P L S P E+ P L + +PQ + +++ P L P E + P Sbjct: 703 EDSPASPPPEDSLMSL--PLEESP--LLPLPEEPQ----LCPRSEGPHLSPRPEEPHLSP 754 Query: 286 RFQPRVLQVQA-QVQSQTQPRIPS-TDTQVQPKLQKQAQ---TQTSPEHLVLQQKQVQPQ 340 R + L QA + QP P +P L QA+ PE L L + +P Sbjct: 755 RPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH 814 Query: 341 LQQ-EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP-PEQTHEQPHTQPQVSLLAPEQ 398 L EP QP+ + + PQ P + P PE++H P + PE+ Sbjct: 815 LSPVPEEPCLSPQPE-----ESHLSPQSEEPC---LSPRPEESHLSPELEKPPLSPRPEK 866 Query: 399 TP 400 P Sbjct: 867 PP 868 Score = 55.5 bits (132), Expect = 2e-07 Identities = 123/493 (24%), Positives = 168/493 (34%), Gaps = 100/493 (20%) Query: 1 MFSQQQQQQLQQQQQQ-----LQQLQQQQLQ---------------QQQLQQQQLLQLQQ 40 + + QQQQQ QQ QQQ L LQQ + QQ QQQQL Q QQ Sbjct: 3852 LVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQ 3911 Query: 41 LLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRG 100 L QQ Q + + QQ QQ L Q + Q+ QQ Q + Sbjct: 3912 LQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQ--QQQQQQFQQQ 3969 Query: 101 YGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQ-FNLSGR---- 155 GL S T L +P QQ +Q LGP G+P P Q F+ G Sbjct: 3970 QQQQQMGLLNQSRT---LLSPQQQQ-----QQQVALGP---GMPAKPLQHFSSPGALGPT 4018 Query: 156 -----NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPC 210 Q + S+ S+ Q P+ + P + E E + D L Sbjct: 4019 LLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLV 4078 Query: 211 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEK-------EPPGQLQVKAQPQARM 263 P P+P+P P RL ++ GQL + +A Sbjct: 4079 ---------QPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEA-S 4128 Query: 264 TVPKQTQTPDL----LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS----------- 308 +VP P + P ++ +L QP ++ +Q+ T P+ P Sbjct: 4129 SVPHLLAQPSVSLGDQPGSMTQNLLGPQQP---MLERPMQNNTGPQPPKPGPVLQSGQGL 4185 Query: 309 -------TDTQVQPKLQKQAQTQTSPEHL-VLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 360 T Q++ +LQ HL QQ+Q+Q L Q Q Q Q + Sbjct: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245 Query: 361 PSVQPQEHPPAQ--VSVQPPEQTHEQPHTQPQVSLLA---PEQTPVVVHVCGLEMPPDAV 415 P Q P Q + QP P T P L A P+ P L PP A+ Sbjct: 4246 PGTQTS---PLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPP------RLPAPPGAL 4296 Query: 416 EAGGGMEKTLPEP 428 G + P P Sbjct: 4297 STGPVLGPVHPTP 4309 Score = 48.1 bits (113), Expect = 3e-05 Identities = 72/299 (24%), Positives = 113/299 (37%), Gaps = 30/299 (10%) Query: 113 LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS---SSTTP 169 L+PP +P P+A+R L PPP +P +P L P +++ S + Sbjct: 449 LSPPPEESPTSPP--PEASR---LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503 Query: 170 NRKDSSSQTMPVEDKS-DPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 228 + SS P+E+ PPE E P ++TP P E+ +P PE Sbjct: 504 SPPPESSPFSPLEESPLSPPE--ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561 Query: 229 EASELP-AKRLR-SSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPR 286 S P A RL EE PP + + P+A P ++P L P E+ + P Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP-LSPPPEESPLSP- 619 Query: 287 FQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 346 S+ P P D+ + P +++ PE L V +L E Sbjct: 620 ---------PPEASRLSP--PPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPE 667 Query: 347 PQKQVQPQVHTQAQPSVQPQE-HPPAQVS--VQPPEQTHEQPHTQPQVSLLAPEQTPVV 402 P + P + PP + S PPE + P + + L E++P++ Sbjct: 668 ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726 Score = 47.4 bits (111), Expect = 5e-05 Identities = 95/416 (22%), Positives = 158/416 (37%), Gaps = 63/416 (15%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQ--------QSPPQAPLPMAV 55 + ++++LQ++QQ QLQ Q QQQQ QQ LL Q SP A + Sbjct: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQL 3313 Query: 56 SRGLP-PQQP--QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPS 112 S GL +QP QPL+ Q A LQ+ L + +G+ ++ Sbjct: 3314 SLGLAGARQPGLPQPLMPTQPPAHA-------LQQRLAPSMAMVSNQGHMLSGQHGGQAG 3366 Query: 113 LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRK 172 L P Q + P L Q +G P + M P Q + Q + ++S P Sbjct: 3367 LVPQQSSQPVLS--------QKPMGTMPPSMCMKPQQLAM-------QQQLANSFFP--- 3408 Query: 173 DSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCP------EDIAKEKRTPAPEP 225 D+ ED DP ++ A + Q + P + ++ + P Sbjct: 3409 DTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSS 3468 Query: 226 EPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 285 + + + RS+ +P++ P Q + Q Q + L Q L Sbjct: 3469 DLQNHVAAGSGQERSAGDPSQPRP----NPPTFAQGVINEADQRQYEEWL---FHTQQLL 3521 Query: 286 RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVL-QQKQVQPQLQQE 344 + Q +VL+ Q V +++ + + + ++ + LV QQ ++Q QL Q Sbjct: 3522 QMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQV 3581 Query: 345 AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 400 + QK+ HT E+ Q Q +Q +Q H+ V L+P Q+P Sbjct: 3582 RKQQKE-----HTNLM-----AEYRNKQQQQQQQQQQQQQQHS--AVLALSPSQSP 3625 Score = 43.5 bits (101), Expect = 8e-04 Identities = 70/328 (21%), Positives = 108/328 (32%), Gaps = 53/328 (16%) Query: 102 GMASPG---LAAPSLTPPQLATPN---------LQQFFPQATRQSLLGPPPVGVPMNPSQ 149 G SPG L P P Q+ + + L+ FP A P P G P P Sbjct: 2152 GPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPM 2211 Query: 150 FNLSGRNPQKQA---RTSSSTTPNRKDSSSQTM-----PVEDKSDPPE----GSEEAAEP 197 S R Q T+ TP + S+ P D PE G +A+EP Sbjct: 2212 LGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEP 2271 Query: 198 RMDTPEDQDLPPCPEDIAKEKRTPAPE---------PEPCEASELPAKRLRSSE------ 242 + P + E +E +P P + L L++ + Sbjct: 2272 LLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPL 2331 Query: 243 ----EPTEKEPPGQ-LQVKAQPQARMTVPKQTQTPDLLPEA------LEAQVLPRFQPRV 291 E + PG L+ + P A+ P PD+ + + PR QP Sbjct: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391 Query: 292 LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQV 351 + + ++ P P + P+ Q +Q+ +P L + P + P Sbjct: 2392 PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451 Query: 352 QPQVHTQAQPSVQPQEHPPAQVSVQPPE 379 +P Q++ P PP QPPE Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRP---QPPE 2476 Score = 37.4 bits (85), Expect = 0.057 Identities = 72/350 (20%), Positives = 121/350 (34%), Gaps = 50/350 (14%) Query: 180 PVEDKSDPPEGSEEAAEPRMDTPEDQDLP----------PCPEDIAKEKRTPAPEPEPCE 229 P+ + PP ++ A+EPR+ + + P PC IA K PAP Sbjct: 3093 PLGPEERPPPAAD-ASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLG 3151 Query: 230 ASELPAKRLRSSEEPTEKEPP----GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 285 P + + S + P G KA A P TP L + +L Sbjct: 3152 LGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLE 3211 Query: 286 RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA 345 +F+ + + T P P+ K++ P L + + ++E Sbjct: 3212 KFE-------LESGALTLPGGPAASGDELDKMESSLVASELP----LLIEDLLEHEKKEL 3260 Query: 346 EPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHV 405 + ++Q+ Q+ Q Q Q+H + +S P Q PH SL +Q Sbjct: 3261 QKKQQLSAQLQPAQQQQQQQQQH--SLLSAPGPAQAMSLPHEGSSPSLAGSQQQL----- 3313 Query: 406 CGLEMPPDAVEAGGGMEKTLPEP-VGTQVSMEEIQNESACGLDVGECENRAREMPGVWGA 464 ++ G + LP+P + TQ +Q A + + N+ + G G Sbjct: 3314 --------SLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAM--VSNQGHMLSGQHGG 3363 Query: 465 GGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 514 L + Q S S P+ +P S+ P + + A FF Sbjct: 3364 QAGL---VPQQSSQPVLSQKPMGTMP---PSMCMKPQQLAMQQQLANSFF 3407 Score = 37.0 bits (84), Expect = 0.074 Identities = 74/378 (19%), Positives = 119/378 (31%), Gaps = 57/378 (15%) Query: 105 SPGLAAPSLTP----PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQ 160 SP P L+P P L+ + + + L P P ++P P Sbjct: 807 SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPEL-----EKPPLS 861 Query: 161 ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDI---AKE 217 R + + + +P+ P S EP + P + L P PE++ Sbjct: 862 PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG 921 Query: 218 KRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV------KAQPQARMTVPKQTQT 271 + + +P+ P + P + ++ P P G+L+ + P++ + P Sbjct: 922 EPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAP----- 976 Query: 272 PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSP--EH 329 LE + P + + P S P L + Q SP +H Sbjct: 977 ------ILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH 1030 Query: 330 LVLQQKQVQPQLQQEAEPQKQVQP--------------QVHTQAQPSVQPQEHPPAQVSV 375 ++ Q Q A P P ++H V E P + Sbjct: 1031 SLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE--- 1087 Query: 376 QPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL---EMPPDAVEAGGGMEKTLPEPVGTQ 432 P T P +S AP P + GL P D ++A G PEP T Sbjct: 1088 --PSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQ----PEPGQTP 1141 Query: 433 VSMEEIQNESACGLDVGE 450 S+ S LD E Sbjct: 1142 GSLASELKGSPVLLDPEE 1159 Score = 30.8 bits (68), Expect = 5.3 Identities = 69/273 (25%), Positives = 99/273 (36%), Gaps = 70/273 (25%) Query: 5 QQQQQLQQQQQQLQQLQ-QQQLQQQQLQQQQLLQLQQLLQQSP-------PQAPLPMAVS 56 Q + + Q+Q+Q+L++L +QQ+Q+ L+Q++ P P +P +S Sbjct: 2674 QTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLS 2733 Query: 57 R---------------GLPPQQPQQPLL--------------------NLQGTNSASLLN 81 R GLPP + P+L + NS L+ Sbjct: 2734 RGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVG 2793 Query: 82 GS--MLQRA-----LLLQQLQGNLRGYGMASPGLAA--------PSLTPPQLATPNLQQF 126 GS QRA L LQQ Q L A+ + PS P+L L Sbjct: 2794 GSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGS- 2852 Query: 127 FPQATRQSLLGPP--PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNR-KDSSSQTMPVED 183 P A + L P PV P P+QF N QK + P + + PV + Sbjct: 2853 -PLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSE 2911 Query: 184 KSDP----PEGSEEAAEPRMDTPEDQDLPPCPE 212 DP PEG A + P+ PP PE Sbjct: 2912 --DPHRLAPEGLRGLAVSGL-PPQKPSAPPAPE 2941 >gi|56549696 E1A binding protein p400 [Homo sapiens] Length = 3122 Score = 78.6 bits (192), Expect = 2e-14 Identities = 122/456 (26%), Positives = 167/456 (36%), Gaps = 112/456 (24%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQ------------------------------ 33 +QQQQQ QQQQQQ QQ QQQQ QQQQ QQQ Sbjct: 2718 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTP 2777 Query: 34 -QLLQLQQLLQQSPPQAPLPMA------------VSRGLPPQQPQQPLLNLQGTNSASLL 80 L+++Q+ Q PPQ P P A V PPQQ L + +LL Sbjct: 2778 EHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALL 2837 Query: 81 NGSM---LQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLG 137 G+ LQ A L + L+ G AP LA P + P A S Sbjct: 2838 TGTTVANLQVARLTRVPTSQLQAQGQMQ--TQAPQPAQVALAKPPVVS-VPAAVVSS--- 2891 Query: 138 PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP 197 P +PMN + +++ PQK A G A+P Sbjct: 2892 PGVTTLPMNVAGISVAIGQPQKAA----------------------------GQTVVAQP 2923 Query: 198 RMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 257 Q L + ++++ A +P+ + +++ + + T PG A Sbjct: 2924 ----VHMQQLLKLKQQAVQQQK--AIQPQAAQGPAAVQQKITAQQITT----PG-----A 2968 Query: 258 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 317 Q + +T L +AQ L Q QVQ Q+Q P++ T V Sbjct: 2969 QQKVAYAAQPALKTQFLTTPISQAQKLAGAQ----QVQTQIQVAKLPQVVQQQTPVASIQ 3024 Query: 318 Q-KQAQTQTSPEHLVL-------QQKQVQPQLQQEAE--PQKQVQPQVHTQAQPSVQPQE 367 Q A Q SP+ + L QQ Q+ P + A+ QK +Q QV T A +Q Sbjct: 3025 QVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPG 3084 Query: 368 HP-PAQV--SVQPPEQTHEQPHTQPQVSLLAPEQTP 400 P PAQV S P Q + P V L P + P Sbjct: 3085 APNPAQVPASSDSPSQQPKLQMRVPAVRLKTPTKPP 3120 Score = 59.7 bits (143), Expect = 1e-08 Identities = 96/423 (22%), Positives = 146/423 (34%), Gaps = 62/423 (14%) Query: 22 QQQLQQQQLQQQQLLQLQ--QLLQQSPPQAPLPMAVS----RGLPPQQPQ---QPLLNLQ 72 QQ+ QQ + Q Q Q QQ PP P P A G P QPQ QP Q Sbjct: 2495 QQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQ 2554 Query: 73 GTNSASLLNGSML---QRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQ 129 + + ++ A+L ++ ++ G M + ++ + N P Sbjct: 2555 PVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIV-------NTIAGVPA 2607 Query: 130 ATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPE 189 AT QS+ + P+ P G + Q + P S + P + Sbjct: 2608 ATFQSI--NKRLASPVAPGALTTPGGSAPAQV-VHTQPPPRAVGSPATATPDLVSMATTQ 2664 Query: 190 GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 249 G +L P + R+ P+ +LP K + Sbjct: 2665 GVRAVTSVTASAVVTTNLTP----VQTPARSLVPQVSQATGVQLPGKTI----------T 2710 Query: 250 PGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPST 309 P Q+ Q Q + +Q Q Q + Q + Q Q Q + +Q ++P Sbjct: 2711 PAHFQLLRQQQQQQQQQQQQQ-----------QQQQQQQQQQQQQQQQTTTTSQVQVPQI 2759 Query: 310 DTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ---VQPQVHTQAQPSVQPQ 366 Q Q Q +A + +PEHL+ QKQ Q PQ Q QP Q Q S PQ Sbjct: 2760 QGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQ 2819 Query: 367 EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL-EMPPDAVEAGGGMEKTL 425 + P +V T P+ L T + V L +P ++A G M+ Sbjct: 2820 QQSPQLTTV-----------TAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQA 2868 Query: 426 PEP 428 P+P Sbjct: 2869 PQP 2871 Score = 38.9 bits (89), Expect = 0.019 Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 28/120 (23%) Query: 204 DQDLPPCP------EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 257 D+ LPP E IAKEK+ A + + +++P +PP Sbjct: 2469 DKPLPPIQVASLRAERIAKEKKALADQ--------------QKAQQPAVAQPP------- 2507 Query: 258 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 317 PQ + P Q Q P LP+ A P P +Q Q Q Q QTQP+ + QP + Sbjct: 2508 PPQPQPPPPPQ-QPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAI 2566 Score = 36.2 bits (82), Expect = 0.13 Identities = 54/247 (21%), Positives = 93/247 (37%), Gaps = 42/247 (17%) Query: 133 QSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQT-MPVEDKSDPPEGS 191 Q L+ G+P P L+G+ +Q S+ P + +S T +P PP G Sbjct: 506 QQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGV 565 Query: 192 EEAA---------EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSE 242 AA +P++ + Q P K ++ P P P +S+LP + ++ Sbjct: 566 PTAALSSALQFAQQPQVVEAQTQLQIP-----VKTQQPNVPIPAP-PSSQLPIPPSQPAQ 619 Query: 243 EPTEKEPPGQLQVKAQ-----PQ----ARMTVPKQTQTPDLLPEALEAQVLP-------- 285 PG++QV+A PQ R+ V P LP + + + P Sbjct: 620 LALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGP 679 Query: 286 ---------RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336 R + + V S+T + S T+ Q Q +Q S + + +Q Sbjct: 680 SPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQIT 739 Query: 337 VQPQLQQ 343 ++ Q+ Q Sbjct: 740 LENQVHQ 746 Score = 34.3 bits (77), Expect = 0.48 Identities = 64/313 (20%), Positives = 102/313 (32%), Gaps = 51/313 (16%) Query: 272 PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV 331 P + +L A+ + + + + L Q + Q + P Q P Q+ P+ Sbjct: 2473 PPIQVASLRAERIAK-EKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAG 2531 Query: 332 LQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQV 391 Q P +Q + +PQ Q QPQ VQ P + T Sbjct: 2532 SQPPAGPPAVQPQPQPQPQTQPQ-------------------PVQAPAKAQPAITTGGSA 2572 Query: 392 SLLAPEQTPVVVHVCGLEMPPDAVEAG--------------GGMEKTLPEPVGTQV---- 433 ++LA + V G MP AV + K L PV Sbjct: 2573 AVLA---GTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTP 2629 Query: 434 ---SMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVP 490 + ++ + VG ++ + G VT + +S A T LTPV Sbjct: 2630 GGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTAS---AVVTTNLTPVQ 2686 Query: 491 RPSDSV---SSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHM 547 P+ S+ S P K + + QQ+ Q + Q QQ+ + Q Sbjct: 2687 TPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQ-QQQQQQQQQQQQQQQQQQQQQQQQQ 2745 Query: 548 SQACLLSLLPVPR 560 Q S + VP+ Sbjct: 2746 QQTTTTSQVQVPQ 2758 Score = 33.9 bits (76), Expect = 0.63 Identities = 48/190 (25%), Positives = 67/190 (35%), Gaps = 23/190 (12%) Query: 85 LQRALLLQQLQGNLRGYGMASPG--LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVG 142 L+ + L Q +Q YG G +A PS PP+ A P PQ L G PP+ Sbjct: 1421 LKASRLFQPVQ-----YGQKPEGRTVAFPSTHPPRTAAPTTASAAPQG---PLRGRPPIA 1472 Query: 143 V-PMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDT 201 NP + QA S+ SS+ P + + +A+ P Sbjct: 1473 TFSANPEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPP 1532 Query: 202 PEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQA 261 P+ P P A + P P +A RL S E QL PQ+ Sbjct: 1533 PQ----PQAPSHAAGQSALPQRLVLPSQAQ----ARLPSG----EVVKIAQLASITGPQS 1580 Query: 262 RMTVPKQTQT 271 R+ P+ T Sbjct: 1581 RVAQPETPVT 1590 Score = 32.3 bits (72), Expect = 1.8 Identities = 76/291 (26%), Positives = 102/291 (35%), Gaps = 59/291 (20%) Query: 289 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHL--------VLQQKQVQPQ 340 P+ Q+ Q QSQ Q PST VQ P L L Q Sbjct: 520 PQAAQLAGQRQSQQQYD-PSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQ 578 Query: 341 LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHE---QPHTQPQVSLLAPE 397 Q E Q Q+Q V TQ QP+V P PP+ PP Q + T +V + A + Sbjct: 579 QPQVVEAQTQLQIPVKTQ-QPNV-PIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQ 636 Query: 398 QTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRARE 457 + + V +P D P P+ T S + S G Sbjct: 637 LSSLPQMVASTRLPVDPA-------PPCPRPLPTS-STSSLAPVSGSG------------ 676 Query: 458 MPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYI 517 PG A S V S+ ++A S V R V+S P +P++ A Sbjct: 677 -PGPSPARSS-PVNRPSSATNKALSPV----TSRTPGVVASAPTKPQSPAQNA------- 723 Query: 518 CKASCSSQQEFQDHMSEP-----QHQQRLGEIQH---MSQACLLSLLPVPR 560 SSQ QD ++E Q QR+ E++ SQ L L PR Sbjct: 724 ----TSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPR 770 >gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] Length = 2063 Score = 75.5 bits (184), Expect = 2e-13 Identities = 123/483 (25%), Positives = 180/483 (37%), Gaps = 92/483 (19%) Query: 2 FSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSP----PQAPLPMAVSR 57 F Q QQQQ QQQQQ QQ QQQQ QQQQ QQ Q QQ QQ P PQ P V Sbjct: 257 FPQLQQQQQQQQQQ--QQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVP- 313 Query: 58 GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLA---APSLT 114 +PP Q P LQ + L + L G ++ A P LA PS Sbjct: 314 -VPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHP 372 Query: 115 PPQLATPNLQQF-----FPQATRQSLLGPP--------PVGVPMNPSQFNLSGRNPQKQA 161 PP + Q FPQ + P P VP Q +L+ ++P Sbjct: 373 PPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSP 432 Query: 162 RT----SSSTTPNRKDSSSQTMPVEDKSDP-PEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216 + S +++P + Q P +++P P+G ++ P Q P + Sbjct: 433 SSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVM 492 Query: 217 EKRTPAPEPEPCE--ASELPAKRLRSSEEPTEKEP---PGQLQVKAQPQARMTVPKQTQT 271 +++ P P+ +P KRL + P GQ+ P T P + Sbjct: 493 QQQPPNQGPQSLHPGLGGMP-KRLPPGFSAGQANPNFMQGQV-----PSTTATTPGNSGA 546 Query: 272 PDLL--------------PEALEAQVL----PRFQPRVLQVQAQVQSQTQ-----PRIPS 308 P L P + QV QP ++ + + +Q P++ Sbjct: 547 PQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNL 606 Query: 309 TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQ-----VHTQAQPSV 363 ++ Q QP+ Q P L+ +Q+ P Q + Q + PQ Q P Sbjct: 607 SNMQGQPQ-------QGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQG 659 Query: 364 QPQEHPPAQ------VSVQPPEQTHEQ-------PHTQ---PQVSLLAPEQTPVVVHVCG 407 Q +PP+Q + PP+Q Q PH Q PQ +L +Q P++ + Sbjct: 660 QMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLL-QQNPMIEQIMT 718 Query: 408 LEM 410 +M Sbjct: 719 NQM 721 Score = 60.1 bits (144), Expect = 8e-09 Identities = 111/464 (23%), Positives = 165/464 (35%), Gaps = 83/464 (17%) Query: 1 MFSQQQQ---QQLQQQQQQLQQLQQQQLQQQQL---QQQQLLQLQQLLQQ-----SPPQA 49 M Q QQ QL QQ+ Q Q +QQQ Q +L QL+ Q +PP Sbjct: 609 MQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQ 668 Query: 50 PLPMAVSRGLPPQQ------PQQ--PLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGY 101 L + R PP+Q PQ P + G LL + + ++ Q+QGN + + Sbjct: 669 NLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQF 728 Query: 102 GMASPGLAAPSLTPPQL---ATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 158 + P P Q+ TPN+Q Q T Q P P+N S + G Q Sbjct: 729 NTQNQSNVMPG--PAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQ 786 Query: 159 -----------KQARTSSSTTPNRKDSSSQTMP----VEDKSDPP-----EGSEEAAE-- 196 Q +TT N S SQ MP + PP +G+ + Sbjct: 787 VLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHF 846 Query: 197 ---------PRMDTPEDQDLPPCPED----IAKEKRTPAPEPEPCEASELPAKR--LRSS 241 P P + C ++ + K+ +P S++ A + + Sbjct: 847 SGHGMSFNAPFSGAPNGNQM-SCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNK 905 Query: 242 EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 301 + T P + K P+ + + TPD P LE QP + Q Sbjct: 906 QNNTNANKP---KKKKPPRKKKNSQQDLNTPDTRPAGLE----EADQPPLPGEQGINLDN 958 Query: 302 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 361 + P++P + P Q Q +Q+ PQL Q P Q PQ Q Q Sbjct: 959 SGPKLPEFSNR-PPGYPSQPVEQR-------PLQQMPPQLMQHVAPPPQ-PPQQQPQPQL 1009 Query: 362 SVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHV 405 Q Q PP+Q P+ +Q Q + +L +Q P V + Sbjct: 1010 PQQQQPPPPSQ-----PQSQQQQQQQQQMMMMLMMQQDPKSVRL 1048 Score = 52.4 bits (124), Expect = 2e-06 Identities = 106/448 (23%), Positives = 169/448 (37%), Gaps = 72/448 (16%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-QLQQLLQQSPPQ-----APLPMA 54 M SQQ Q + Q + Q LQQ + +Q + Q+Q QQ Q P P Sbjct: 683 MLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQ 742 Query: 55 VSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGNLRGYGMASPGLAAPS 112 + RG P Q ++ G S +L G + + +QG + SP +A Sbjct: 743 IMRGPTPNM-QGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQH 801 Query: 113 LTPPQLATPN--LQQFFPQAT-RQSLLGPPPV----------------GVPMN------P 147 P A + L Q P + +Q+ + PP V G+ N P Sbjct: 802 GDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAP 861 Query: 148 SQFNLS-GRNP----QKQARTSSSTTPN--RKDSSSQTMPVEDKSDPPEGSEEAAEPRMD 200 + +S G+NP K +S N + D S+ V +K + + A +P+ Sbjct: 862 NGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNK----QNNTNANKPKKK 917 Query: 201 TPEDQDLPPCPEDIAKEKRTPAPEPEPCEASE---LPAKRLRSSEEPTEKEPPGQLQVKA 257 P P ++ ++ TP P E ++ LP ++ + + K P + Sbjct: 918 KP-----PRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLP----EFSN 968 Query: 258 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 317 +P + P + + +P L V P QP Q Q Q+ Q QP PS QP+ Sbjct: 969 RPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPS-----QPQS 1023 Query: 318 QKQAQTQTSPEHLVLQQKQVQ----PQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 373 Q+Q Q Q +++ Q+ + P Q P+ + P +Q P +Q P V Sbjct: 1024 QQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPD--SQRMP-MQQSGSVPVMV 1080 Query: 374 SVQPPEQTHEQPHTQPQVSLLAPEQTPV 401 S+Q P P Q + P TP+ Sbjct: 1081 SLQGPASVPPSPDKQ---RMPMPVNTPL 1105 Score = 52.4 bits (124), Expect = 2e-06 Identities = 95/428 (22%), Positives = 153/428 (35%), Gaps = 64/428 (14%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL-PPQ 62 QQ Q QL QQQQ Q Q QQQQ QQQ ++ L ++QQ P LP VS+ + PP+ Sbjct: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML--MMQQDPKSVRLP--VSQNVHPPR 1058 Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPN 122 P LN +GS+ ++ LQG P+ PP +P+ Sbjct: 1059 GP----LNPDSQRMPMQQSGSV----PVMVSLQG--------------PASVPP---SPD 1093 Query: 123 LQQFFPQATRQSLLGPPPVGVPMNPSQ----FNLSGRNPQKQARTSSSTTPNRKDSSSQT 178 Q+ P PV P+ + + S +NP ++ P S + + Sbjct: 1094 KQRM-----------PMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPS 1142 Query: 179 MPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRL 238 +P + P + M P+ P A ++ P P + Sbjct: 1143 VPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP--NV 1200 Query: 239 RSSEEPTEKEPPGQLQVKA-QPQARMTVPKQTQTPD--LLPEALEAQVLPRFQPRV---L 292 + + + + P + + PQ P T+ + L PE L A + F P++ L Sbjct: 1201 AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL 1260 Query: 293 QVQAQV-----QSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEP 347 + + Q P Q L +P+ L V Q + Sbjct: 1261 PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA 1320 Query: 348 QKQVQPQVHTQAQPSVQPQEHP-PAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP--VVVH 404 K+ P ++ P + P P + + + P+ T +Q +LL + P V+V Sbjct: 1321 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLA---SQTNAALLQNVELPRNVLVS 1377 Query: 405 VCGLEMPP 412 L PP Sbjct: 1378 PTPLANPP 1385 Score = 45.1 bits (105), Expect = 3e-04 Identities = 63/299 (21%), Positives = 94/299 (31%), Gaps = 40/299 (13%) Query: 116 PQLATPNLQQFFPQATRQSLLGPP-----PVGV--PMNPSQFNLSGRNPQKQARTSSSTT 168 P L+ ++QQ Q+ L PP PV V MNP+ F + Q+Q + Sbjct: 219 PLLSGLHIQQ---QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQ 275 Query: 169 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP------- 221 ++ Q + + + P+ P +PP + P Sbjct: 276 QQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSL 335 Query: 222 -----------APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ 270 AP P P + L + + P+ PP + QA P+ + Sbjct: 336 GTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSN 395 Query: 271 TPDL-LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 329 P+ Q P P LQ QP + + P +Q +SP Sbjct: 396 PGQFTAPQMKSLQGGPSRVPTPLQ---------QPHLTNKSPASSPSSFQQGSPASSPTV 446 Query: 330 LVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPP--AQVSVQPPEQTHEQPH 386 QQ+ Q PQ QP P VQ PP + QPP Q + H Sbjct: 447 NQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLH 505 Score = 42.0 bits (97), Expect = 0.002 Identities = 46/185 (24%), Positives = 71/185 (38%), Gaps = 31/185 (16%) Query: 198 RMDTPEDQDLPPCPEDIAKEKRTPAPEPE-------PCEASELPAKRLRSSEEPTEKEPP 250 RM+ P +PP +++ P P PE P S+ L + P Sbjct: 175 RMNNPATVMIPP-GGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPS 233 Query: 251 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 310 G L P + P ++ Q+ P P++ Q Q Q Q Q Q + Sbjct: 234 GSLAPPHHP--------------MQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQ----Q 275 Query: 311 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPP 370 Q Q + Q+Q Q + +H Q + ++PQ A Q V P + ++QP PP Sbjct: 276 QQQQQQQQQQLQARPPQQHQQQQPQGIRPQF--TAPTQVPVPPGWNQLPSGALQP---PP 330 Query: 371 AQVSV 375 AQ S+ Sbjct: 331 AQGSL 335 >gi|38788274 bromodomain PHD finger transcription factor isoform 1 [Homo sapiens] Length = 2920 Score = 72.0 bits (175), Expect = 2e-12 Identities = 104/407 (25%), Positives = 160/407 (39%), Gaps = 57/407 (14%) Query: 23 QQLQQQQLQQQQL---LQLQQLLQQSPPQAPLPMAVSRG------LPPQQPQQPLLNLQG 73 QQ+ Q ++ Q + + + +P Q L A S P +PQQ + L Sbjct: 2090 QQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTM 2149 Query: 74 TNSASLLNGSMLQRAL-LLQQLQGNLRGYGMASPG----LAAPSLTPPQLATPN--LQQF 126 L G + L ++ Q QG G P L P Q A PN +Q+F Sbjct: 2150 AQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRF 2209 Query: 127 F--PQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDK 184 P AT + V + G Q+Q++ S P + +T+P Sbjct: 2210 LFTPLATTATTASTTTTTVSTTAA-----GTGEQRQSKLS----PQMQVHQDKTLPPAQS 2260 Query: 185 SD--PPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAK----RL 238 S P E + A+P P+ Q P P + + P + + +S +P++ Sbjct: 2261 SSVGPAEAQPQTAQPSAQ-PQPQTQPQSPAQ-PEVQTQPEVQTQTTVSSHVPSEAQPTHA 2318 Query: 239 RSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ----TPDLLPEALEAQVLPR------FQ 288 +SS+ + Q V+ Q R+ P QT+ TP L ++QV Q Sbjct: 2319 QSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQ 2378 Query: 289 PRV-LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ------PQL 341 P LQ+ +Q Q Q+QP++ S+ + T +SP LQ +Q Q PQL Sbjct: 2379 PHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQL 2438 Query: 342 QQEAEPQKQVQPQV--HTQAQPSVQPQE---HPPAQVSVQPPEQTHE 383 QQ+ + Q+Q QV QAQ S PQ+ P Q+ QTH+ Sbjct: 2439 QQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQ 2485 Score = 65.9 bits (159), Expect = 1e-10 Identities = 49/157 (31%), Positives = 73/157 (46%), Gaps = 11/157 (7%) Query: 258 QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 316 Q Q++++ Q LP A + V P QP+ Q AQ Q QTQP+ P+ QP+ Sbjct: 2238 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2292 Query: 317 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--KQVQPQVHTQAQPSVQPQEHPPAQVS 374 +Q Q + QT + QP Q ++PQ Q QPQ + Q Q V+ Q P+Q Sbjct: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQS--PSQTR 2350 Query: 375 VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 411 ++P + P Q QV + P+ H L++P Sbjct: 2351 IRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2386 Score = 58.2 bits (139), Expect = 3e-08 Identities = 94/422 (22%), Positives = 160/422 (37%), Gaps = 51/422 (12%) Query: 6 QQQQLQQQQQQLQQLQQQ-----------QLQQQQLQQQQLLQLQQLLQQSPPQAPLPMA 54 QQ Q++ QL QL Q Q Q Q Q QL+ + P Q + A Sbjct: 2141 QQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAA 2200 Query: 55 VSRGLPPQQPQQPLLNLQGTNSASLLN--------GSMLQRALLLQQLQGNLRGYGMASP 106 + G + PL T S + G Q L Q + A Sbjct: 2201 MPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQS 2260 Query: 107 GLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSS 166 P+ PQ A P+ Q P P P +P+Q + + + T SS Sbjct: 2261 SSVGPAEAQPQTAQPSAQ-------------PQPQTQPQSPAQPEVQTQPEVQTQTTVSS 2307 Query: 167 TTPNRKD---SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDL-PPCPEDIAKEKRTPA 222 P+ + S V +S P + + R+ +P + P P ++ +++ Sbjct: 2308 HVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQS-- 2365 Query: 223 PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQ 282 + + + +P + S + P++ +P Q QV++ Q + Q P + Q Sbjct: 2366 -QVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQ 2424 Query: 283 VLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS--PEHLVLQQKQVQPQ 340 + + QP+V+ V Q+Q Q Q +Q+Q ++ Q Q Q S P+ + LQ + Q Sbjct: 2425 I-QQPQPQVIAVP-QLQQQVQVL-----SQIQSQVVAQIQAQQSGVPQQIKLQ---LPIQ 2474 Query: 341 LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 400 +QQ + Q V T SVQ Q Q+ Q ++ +Q + + +L A Q+ Sbjct: 2475 IQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSE 2534 Query: 401 VV 402 ++ Sbjct: 2535 II 2536 Score = 32.7 bits (73), Expect = 1.4 Identities = 90/469 (19%), Positives = 153/469 (32%), Gaps = 62/469 (13%) Query: 140 PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 199 P+GVP P + PQ++ SS+ P R ++ QT PV ++ E E E R Sbjct: 1844 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 1899 Query: 200 DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 258 +++ E AK++ ++ P S+ P +K + Sbjct: 1900 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 1959 Query: 259 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 308 +M + + +P + F V Q Q+ QVQ + IPS Sbjct: 1960 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2019 Query: 309 --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 350 T T QP+ T+ V+ Q++P + P +Q Sbjct: 2020 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2079 Query: 351 --VQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL 408 V Q Q Q P +V P P Q SL + T + Sbjct: 2080 TPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTP---GQKSLTSATSTSNI--QSSA 2134 Query: 409 EMPPDAVEAGGGMEKTLPEPV-------GTQVSMEEIQNESACGLDVGECENRAREMPGV 461 PP + G ++ T+ + G Q IQ + G G+ + + + + Sbjct: 2135 SQPPRPQQ--GQVKLTMAQLTQLTQGHGGNQGLTVVIQGQ---GQTTGQLQLIPQGVTVL 2189 Query: 462 WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS 521 G G L + + + F PL + + ++T + T+ + + Q Sbjct: 2190 PGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQ------SKL 2243 Query: 522 CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEP 570 Q QD P +G + Q S P P +T+ + P Sbjct: 2244 SPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP----QTQPQSP 2288 Score = 32.0 bits (71), Expect = 2.4 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 16/98 (16%) Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQ-----QLQQQQLLQLQQLLQQSPPQAPLPMAVSR 57 S + QLQ QQ Q Q + QLQQQ Q+Q Q + Q+Q Q+ +P + Sbjct: 2416 SSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQ------AQQSGVPQQIKL 2469 Query: 58 GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQ 95 LP Q Q + + N +Q A + +QLQ Sbjct: 2470 QLPIQIQQS-----SAVQTHQIQNVVTVQAASVQEQLQ 2502 Score = 31.6 bits (70), Expect = 3.1 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%) Query: 629 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 681 + D E + E+++ ++E+ +GD EE +D ED+EE E+EE+ Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169 Score = 30.0 bits (66), Expect = 9.0 Identities = 17/60 (28%), Positives = 26/60 (43%) Query: 208 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 267 P P A E+ PAP P P + P LRS + + Q + P+ R++ P+ Sbjct: 9 PKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPR 68 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 68.9 bits (167), Expect = 2e-11 Identities = 98/397 (24%), Positives = 149/397 (37%), Gaps = 41/397 (10%) Query: 13 QQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQ 72 ++Q L QLQQ Q Q Q Q Q +LQ L PP P P+ G QP P + Sbjct: 54 REQHLAQLQQLQ-QMHQKQMQCVLQPHHL--PPPPLPPPPVMPGGGYGDWQPPPPPMPPP 110 Query: 73 GTNSASLLNGSMLQRALLLQQLQG--NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQA 130 + S + +L Q G L + SP + P PP P Q + P Sbjct: 111 PGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPP--VPPGSYMPPSQSYMPPP 168 Query: 131 TRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEG 190 PP P P ++P Q+ + + + + SSSQ+ +S P Sbjct: 169 QPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSS 228 Query: 191 SEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP- 249 + P + Q L P P +T + EP E+ AK + ++ EP Sbjct: 229 QASPSRPSQGHSKSQLLAPPPPSAPPGNKTTV-QQEPLESG---AKNKSTEQQQAAPEPD 284 Query: 250 PGQLQVKAQPQ---ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQ--- 303 P + + Q Q + + Q +T LP + V+ + P ++ + V + +Q Sbjct: 285 PSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPE 344 Query: 304 ------PRIPSTDTQVQPKL-QKQAQTQTSPEHLVLQQKQV-----QPQLQQEAEPQKQV 351 P +P + +V P L ++ Q++ E L+Q Q Q Q Q Q Sbjct: 345 SPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQG 404 Query: 352 QPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 388 Q HTQ Q +Q Q +QPP PH Q Sbjct: 405 IMQKHTQLQQILQQY-----QQIIQPP------PHIQ 430 Score = 44.7 bits (104), Expect = 4e-04 Identities = 77/296 (26%), Positives = 102/296 (34%), Gaps = 36/296 (12%) Query: 5 QQQQQLQQQQQQLQQLQQ-----------QQLQQQQLQQQQLLQLQQLLQQSPPQAPLPM 53 Q+ QLQQ QQ QQ+ Q QL+ ++QQQ Q Q L Q+ + L Sbjct: 407 QKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQ---QFQHLYQEWEREFQLWE 463 Query: 54 AVSRGLPP----QQPQQPLLNLQGTNSA--SLLNGSMLQRALLLQQLQGNLR------GY 101 P Q+ ++ QG A S L + + Q GN+ Y Sbjct: 464 EQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPY 523 Query: 102 GMASPGLAA--PSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQK 159 P L P + PP L P + P AT PPPV P P+ G P Sbjct: 524 SQMPPPLPTMPPPVLPPSLPPPVMPPALP-ATVPPPGMPPPVMPPSLPTSVPPPGMPPSL 582 Query: 160 QARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKR 219 + P SS+ PV PP S A P M P P P I Sbjct: 583 SSAGPPPVLPPPSLSSAGPPPV---LPPPSLSSTAPPPVMPLPPLSSATP-PPGIPPPGV 638 Query: 220 TPAPEPEPCEASELPAKRLRSSEEPTEKEP---PGQLQVKAQPQARMTVPKQTQTP 272 P+ A PA +SS+ P + P P + + P P Q+ P Sbjct: 639 PQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGP 694 Score = 35.4 bits (80), Expect = 0.22 Identities = 29/120 (24%), Positives = 43/120 (35%), Gaps = 10/120 (8%) Query: 259 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ 318 P ++M P T P +LP +L V+P P + P +P T V P Sbjct: 522 PYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLP---TSVPPPGM 578 Query: 319 KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPP 378 + + P ++ P L P P + + A P V P PP + PP Sbjct: 579 PPSLSSAGPPPVL-----PPPSLSSAGPPPVLPPPSLSSTAPPPVMPL--PPLSSATPPP 631 >gi|118498345 AT-binding transcription factor 1 [Homo sapiens] Length = 3703 Score = 67.0 bits (162), Expect = 7e-11 Identities = 85/324 (26%), Positives = 123/324 (37%), Gaps = 45/324 (13%) Query: 106 PGLAAPSL---TPPQLAT----PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 158 PGL +PSL TP A PNL P T S G P G+P PS +LS P Sbjct: 3127 PGLNSPSLPGFTPSNTALTSPKPNLMGL-PSTTVPSP-GLPTSGLPNKPSSASLSSPTPA 3184 Query: 159 KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 218 + P ++ Q P + PP ++ P++ + Q + KEK Sbjct: 3185 QATMAMGPQQPPQQQQQQQ-QPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEK 3243 Query: 219 RT---------PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 269 P P+ E EA A + S+ PT + Q++A A + P Sbjct: 3244 EKAHKGKGEPLPVPKKEKGEAPTATAATI-SAPLPTMEYAVDPAQLQALQAALTSDPTAL 3302 Query: 270 QTPDLLPEALEAQVLPRFQPRVL-QVQAQVQS-------------QTQPRIPSTDTQVQP 315 T LP +P F P Q+ +QS P + + P Sbjct: 3303 LTSQFLP-----YFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSP 3357 Query: 316 K--LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 373 LQ+ Q Q S + + QQ+Q Q Q QQ+ + Q+Q T P + PA+ Sbjct: 3358 GSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKE 3417 Query: 374 SVQPPEQTHEQPHTQPQVSLLAPE 397 S +P EQ +T +VS L P+ Sbjct: 3418 SPKP----EEQKNTPREVSPLLPK 3437 Score = 55.5 bits (132), Expect = 2e-07 Identities = 107/436 (24%), Positives = 152/436 (34%), Gaps = 60/436 (13%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQ-------------QQQLQQQQLLQLQQLLQQSPP 47 M + +QQQQ QQQQQQ QQ QQQQ Q QQ+LQQQ L QL +P Sbjct: 1718 MIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLF--NPT 1775 Query: 48 QAP-LPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASP 106 P PM L QQ Q L ++ LN + +L + L G G P Sbjct: 1776 LLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEV---SLPVTSGALTLTGTG---P 1829 Query: 107 GLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSS 166 GL Q+ + QQ PQ + L + PSQ +P+K+ + Sbjct: 1830 GLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQ------HPEKK----NK 1879 Query: 167 TTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE 226 K+ SQ + D EG E P+ + LP + K++ P E Sbjct: 1880 LVIKEKEKESQR-----ERDSAEGGEGNTGPK------ETLPDALKAKEKKELAPGGGSE 1928 Query: 227 PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP--EALEAQVL 284 P A R + E G V + + V K+ D E LE Sbjct: 1929 PSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGENLEKLECDSC 1988 Query: 285 PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE 344 + +L +++ + Q P + K + + P ++PQ + Sbjct: 1989 GKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYP---------LRPQTPEP 2039 Query: 345 AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP---PEQTHEQPHTQPQVSLLAPEQTPV 401 P P A P QP P S P P QP + P L P + P+ Sbjct: 2040 PPPPPPPPPPPLPAAPP--QPASTPAIPASAPPITSPTIAPAQP-SVPLTQLSMPMELPI 2096 Query: 402 VVHVCGLEMPPDAVEA 417 + MP + A Sbjct: 2097 FSPLMMQTMPLQTLPA 2112 Score = 49.7 bits (117), Expect = 1e-05 Identities = 74/235 (31%), Positives = 99/235 (42%), Gaps = 46/235 (19%) Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQ--QQQLLQLQQL--LQQSPPQAP---LPMAV 55 S Q Q ++Q Q +LQQQ+ +Q+ QQ+L QL L L Q PPQAP P+ Sbjct: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQ 2496 Query: 56 SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTP 115 S P Q PL L + L N L L Y LA PS Sbjct: 2497 SSPSPSQLSHLPLKPLHTSTPQQLAN------------LPPQLIPYQCDQCKLAFPSFEH 2544 Query: 116 PQ-------LATPNLQQFFPQATRQSLLGPPPVGVPMNP---SQFNLSGRNPQKQARTSS 165 Q L+ N Q PQ +SL P + P NP SQ LSG PQ A SS Sbjct: 2545 WQEHQQLHFLSAQN-QFIHPQFLDRSLDMPFMLFDPSNPLLASQL-LSGAIPQIPA--SS 2600 Query: 166 STTPNRKDSSSQTM--PVEDKSDPPEGSEEAA----EPRMD-------TPEDQDL 207 +T+P+ S+ T+ +E+K+ G ++ EP+ D TPE ++ Sbjct: 2601 ATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQLEI 2655 Score = 47.4 bits (111), Expect = 5e-05 Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 25/218 (11%) Query: 515 CYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRR 574 C +C+ + + FQ H +H Q+ + H+ + + + + P Sbjct: 986 CKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGN-----PVHL 1040 Query: 575 WCNTCQLY---------------YMGDLIQHRRTQDHK--IAKQSLRPFCTVCNRYFKTP 617 CN C Y + L ++ Q H+ + +S C +CN K Sbjct: 1041 KCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAK 1100 Query: 618 RKFVEHVKSQGHK--DKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEE-EDDEDEE 674 ++HV+S H+ + ++L+ L+K + +DED C D EE ED E Sbjct: 1101 LNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPS 1160 Query: 675 EIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDF 712 E + E + + S + + T SP T+ + F Sbjct: 1161 ETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISF 1198 Score = 43.1 bits (100), Expect = 0.001 Identities = 24/49 (48%), Positives = 29/49 (59%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLP 52 QQ QQ Q Q+ +QQ QQ+QLQQQQ Q+ Q Q + PP AP P Sbjct: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP 3410 Score = 40.4 bits (93), Expect = 0.007 Identities = 22/55 (40%), Positives = 30/55 (54%) Query: 10 LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64 L QQ QQ QQ Q+ +QQQQ +Q Q Q Q++ QQ P + P+ P + P Sbjct: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDP 3414 Score = 39.7 bits (91), Expect = 0.011 Identities = 80/367 (21%), Positives = 137/367 (37%), Gaps = 58/367 (15%) Query: 292 LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--- 348 LQ+ A+ + + +PKL + Q P +Q Q +P+LQQ+ +P+ Sbjct: 2407 LQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQ--PNQTQEKQGQPKPELQQQEQPEQKT 2464 Query: 349 ---KQVQPQVHT-----QAQPSVQPQEHPPAQVSVQPPEQTH-----EQPHTQPQVSLLA 395 +Q PQ+ + Q P P + P Q S P + +H T Q++ L Sbjct: 2465 NTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLP 2524 Query: 396 PEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 455 P+ P C L P E Q+ QN+ + +R+ Sbjct: 2525 PQLIPYQCDQCKLAFP--------SFEHWQEH---QQLHFLSAQNQ----FIHPQFLDRS 2569 Query: 456 REMP-GVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 514 +MP ++ L + L S + +P S + STP +T K+ L+ Sbjct: 2570 LDMPFMLFDPSNPLLASQLLSG--------AIPQIPASSATSPSTPTSTMNTLKRKLEE- 2620 Query: 515 CYICKASCS-SQQEFQDHMSEPQHQQRL------GEIQHMSQACLLSLLPVPRDVLETED 567 KAS S + + EPQ +RL +++ + Q LL P R +L+ Sbjct: 2621 ----KASASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPT-RKMLDHIA 2675 Query: 568 EEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQ 627 E ++ Q+++ + R+ Q + C C FK H++S+ Sbjct: 2676 HEVGLKK--RVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSR 2733 Query: 628 GHKDKAK 634 H +AK Sbjct: 2734 -HWHEAK 2739 Score = 37.4 bits (85), Expect = 0.057 Identities = 54/261 (20%), Positives = 91/261 (34%), Gaps = 33/261 (12%) Query: 4 QQQQQQLQQQQQQLQQ----------------LQQQQLQQQQLQQQQLLQLQQLLQQSPP 47 Q QQQ QQQQ Q+QQ LQQQQ Q++ +++ + ++ + Sbjct: 3194 QPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQ-QRKDKDSEKVKEKEKAHKGKGE 3252 Query: 48 QAPLP------------MAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQ-L 94 P+P +S LP + LQ +A + + L + L + Sbjct: 3253 PLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFV 3312 Query: 95 QGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSG 154 G Y PG P L + P A Q+L+G P + Q+ S Sbjct: 3313 PGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSP-ALSQALMGLSPGSLLQQYQQYQQSL 3371 Query: 155 RNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDI 214 + +Q + ++ Q PP +P ++P+ ++ P ++ Sbjct: 3372 QEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREV 3431 Query: 215 AK--EKRTPAPEPEPCEASEL 233 + K PE E A L Sbjct: 3432 SPLLPKLPEEPEAESKSADSL 3452 Score = 37.0 bits (84), Expect = 0.074 Identities = 46/202 (22%), Positives = 74/202 (36%), Gaps = 31/202 (15%) Query: 153 SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP--PC 210 +G K A S+ ++ Q P + + PE ++ P+ P+ LP P Sbjct: 2425 AGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPE--QKTNTPQQKLPQLVSLPSLPQ 2482 Query: 211 PEDIAKEKRTPAPE--PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP-- 266 P A + P P+ P P + S LP K L +S P QL Q ++ P Sbjct: 2483 PPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSF 2542 Query: 267 ---------------KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI----- 306 Q P L +L+ + F P + +Q+ S P+I Sbjct: 2543 EHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFM-LFDPSNPLLASQLLSGAIPQIPASSA 2601 Query: 307 --PSTDTQVQPKLQKQAQTQTS 326 PST T L+++ + + S Sbjct: 2602 TSPSTPTSTMNTLKRKLEEKAS 2623 Score = 33.9 bits (76), Expect = 0.63 Identities = 18/50 (36%), Positives = 27/50 (54%) Query: 315 PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ 364 P K+A + + + +Q+Q Q Q QQ+ + Q+Q Q Q QAQ VQ Sbjct: 1704 PSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQ 1753 Score = 33.5 bits (75), Expect = 0.82 Identities = 15/34 (44%), Positives = 23/34 (67%) Query: 661 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISRE 694 E + EEEE++E+EEE E E+E CK + ++ E Sbjct: 469 EEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502 Score = 32.0 bits (71), Expect = 2.4 Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 6/73 (8%) Query: 294 VQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQP 353 + A + S ++P+ + +Q Q Q QQ+Q Q Q QQ+A+ Q Q Sbjct: 1697 IGANIASPSEPKEANRKKLADMIASRQQQQQQQ------QQQQQQQQQQQQAQTLAQAQA 1750 Query: 354 QVHTQAQPSVQPQ 366 QV Q +Q Q Sbjct: 1751 QVQAHLQQELQQQ 1763 Score = 30.8 bits (68), Expect = 5.3 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 9/54 (16%) Query: 637 KSLEKEIAGQDEDHFITVDAVGCF---------EGDEEEEEDDEDEEEIEVEEE 681 KS E + +G E V CF E +EEEEE++ +EEE E EEE Sbjct: 429 KSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEE 482 Score = 30.4 bits (67), Expect = 6.9 Identities = 14/21 (66%), Positives = 17/21 (80%) Query: 661 EGDEEEEEDDEDEEEIEVEEE 681 E +EEEEE +E+EEE E EEE Sbjct: 464 EEEEEEEEAEEEEEEEEEEEE 484 >gi|119943102 CREB binding protein isoform b [Homo sapiens] Length = 2404 Score = 66.6 bits (161), Expect = 9e-11 Identities = 77/252 (30%), Positives = 107/252 (42%), Gaps = 45/252 (17%) Query: 2 FSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61 + + ++QL QQQQQ QQ QQQQ QQQQ + Q PQ P G PP Sbjct: 2151 YREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGP------GGYPP 2204 Query: 62 ----QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQ 117 QQ Q L LQG+ SM Q A + QL M PGL A S Sbjct: 2205 AMQQQQRMQQHLPLQGS--------SMGQMAAQMGQLG------QMGQPGLGADS----- 2245 Query: 118 LATPNLQQFFPQATRQ-----SLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRK 172 TPN+QQ Q Q +G P PM+P Q LSG+ PQ +S P ++ Sbjct: 2246 --TPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQ-PQ------ASHLPGQQ 2296 Query: 173 DSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP-PCPEDIAKEKRTPAPEPEPCEAS 231 ++S + V + P + ++P +P + P P P ++ + +P P AS Sbjct: 2297 IATSLSNQVRSPA-PVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMAS 2355 Query: 232 ELPAKRLRSSEE 243 + L + E+ Sbjct: 2356 SIDQGHLGNPEQ 2367 Score = 60.8 bits (146), Expect = 5e-09 Identities = 88/353 (24%), Positives = 128/353 (36%), Gaps = 66/353 (18%) Query: 85 LQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVP 144 LQ+A L+++ + + L +P+ PP TP Q PQ T Q P P V Sbjct: 1821 LQQAQLMRRRMATMNTRNVPQQSLPSPTSAPP--GTPTQQPSTPQ-TPQPPAQPQPSPVS 1877 Query: 145 MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPED 204 M+P+ F ART TT + +SQ + PP + EAA + Sbjct: 1878 MSPAGF-------PSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQ 1930 Query: 205 QD----------LPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQ 254 Q +PP + TP + P + ++ P+ PPGQ Q Sbjct: 1931 QQHLYRVNINNSMPPGRTGMG----TPGSQMAPVSLNVPRPNQVSGPVMPSM--PPGQWQ 1984 Query: 255 VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDT--Q 312 PQ Q +P V+ +QAQ + PR+PS Sbjct: 1985 QAPLPQQ--------------------QPMPGLPRPVISMQAQA-AVAGPRMPSVQPPRS 2023 Query: 313 VQPK-LQKQAQTQTSPEHLVLQQKQVQ-----PQLQQEAEPQKQVQPQVHTQAQPSVQPQ 366 + P LQ +T SP QQ+ + PQL Q+ + + QP +QPQ Sbjct: 2024 ISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAK---YVANQPGMQPQ 2080 Query: 367 EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGG 419 +Q +QP H+QP Q ++ A P V PP GG Sbjct: 2081 PGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGV--------PPQQQAMGG 2125 Score = 55.5 bits (132), Expect = 2e-07 Identities = 91/422 (21%), Positives = 147/422 (34%), Gaps = 64/422 (15%) Query: 7 QQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQ 66 + +L+QQQ Q +LQQ QL ++++ + Q SP AP + PQ PQ Sbjct: 1809 KHKLRQQQIQ-HRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQP 1867 Query: 67 PLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQF 126 P Q S ++ + Q G + P PP A +Q Sbjct: 1868 P---AQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQI 1924 Query: 127 FPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSD 186 +A +Q L + M P + + P Q S P S MP S Sbjct: 1925 EREAQQQQHLYRVNINNSMPPGRTGMG--TPGSQMAPVSLNVPRPNQVSGPVMP----SM 1978 Query: 187 PPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK--------RTPAPEPEPCEASELPAKRL 238 PP ++A P+ Q +P P + + R P+ +P + L Sbjct: 1979 PPGQWQQA-----PLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLL 2033 Query: 239 RSSEEPTEKEPPGQLQ--VKAQPQARMTVPKQ------TQTPDLLPE-------ALEAQV 283 R+ + P+ + Q+ +K+ PQ KQ P + P+ ++ Q Sbjct: 2034 RTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQP 2093 Query: 284 LPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQ-------------TQTSPEHL 330 QP + + A +P +P Q L Q Q +P++ Sbjct: 2094 GMHQQPSLQNLNAMQAGVPRPGVP-PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYR 2152 Query: 331 VLQQKQVQPQLQQEAEPQKQVQPQV------------HTQAQPSVQPQEHPPAQVSVQPP 378 + ++Q+ Q QQ+ + Q+Q Q Q H Q Q P +PPA Q Sbjct: 2153 EMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRM 2212 Query: 379 EQ 380 +Q Sbjct: 2213 QQ 2214 Score = 45.8 bits (107), Expect = 2e-04 Identities = 87/378 (23%), Positives = 133/378 (35%), Gaps = 70/378 (18%) Query: 27 QQQLQQQQLLQL-QQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSML 85 Q++L++++ +L +Q + + P P P A +P QP +P NG + Sbjct: 624 QKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPP------------NGPLS 671 Query: 86 QRALLLQQLQGNLRGYGMASPGLAAPSLTP--PQLATPNLQQFFPQATRQSLLGPPPVGV 143 +Q QG + + S G P P+ A+P + + + +G P G+ Sbjct: 672 LPVNRMQVSQG-MNSFNPMSLGNVQLPQAPMGPRAASP-----MNHSVQMNSMGSVP-GM 724 Query: 144 PMNPSQF----NLSG---RNPQKQARTSSSTTP-NRKDSSSQTMPVEDKSDPPEGSEEAA 195 ++PS+ N+ G N QA S P N+ SSS M V Sbjct: 725 AISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSV-------------- 770 Query: 196 EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC-----EASELPAKRLRSSEEPTEKEPP 250 PP +++ + A P P +AS+LP + S P PP Sbjct: 771 --------GMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQS--PLHPTPP 820 Query: 251 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS-T 309 P + T P P + P A P + Q + T +PS T Sbjct: 821 PASTAAGMPSLQHTTP-----PGMTPPQPAAPTQPSTP---VSSSGQTPTPTPGSVPSAT 872 Query: 310 DTQVQPKLQK--QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQE 367 TQ P +Q QAQ P+ V PQ Q+ QP +Q + Sbjct: 873 QTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDN 932 Query: 368 HPPAQVSVQPPEQTHEQP 385 P SV E +QP Sbjct: 933 RVPTPSSVASAETNSQQP 950 Score = 45.8 bits (107), Expect = 2e-04 Identities = 76/354 (21%), Positives = 127/354 (35%), Gaps = 50/354 (14%) Query: 20 LQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASL 79 + Q Q Q L Q Q + Q P VS+G P LN+ G ++ L Sbjct: 746 MAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQL 805 Query: 80 LNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPP 139 + Q L + + P +TPPQ A P +T S G Sbjct: 806 PCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPT-----QPSTPVSSSGQT 860 Query: 140 PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRK----------DSSSQTMPVEDKSDPPE 189 P P + + P QA + TP + SSQ P + PP Sbjct: 861 PTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPG 920 Query: 190 GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 249 A +D + P P +A + T + +P P ++P +++ + + EP Sbjct: 921 TPLSQAAASID-----NRVPTPSSVASAE-TNSQQPGP----DVPVLEMKTETQAEDTEP 970 Query: 250 -PGQLQVKAQPQARMT------VPKQTQTPDLLPEALEAQVLPRFQPRV-LQVQAQVQSQ 301 PG + K +P++ M + + D+ + E + +P V ++V+ + +S Sbjct: 971 DPG--ESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESS 1028 Query: 302 TQPRIPSTDTQVQPKLQ-------KQAQTQT-------SPEHLVLQQKQVQPQL 341 + + + QP+ + +QA T PE L +Q V PQL Sbjct: 1029 SNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQ-PVDPQL 1081 Score = 42.7 bits (99), Expect = 0.001 Identities = 62/240 (25%), Positives = 87/240 (36%), Gaps = 66/240 (27%) Query: 6 QQQQLQQQQQQLQQLQQQQLQQQ-------------QLQQQQ-------LLQLQQLLQQS 45 ++Q LQQQQQQ QQ QQQQ QQQ Q QQ Q +Q QQ +QQ Sbjct: 2156 RRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQH 2215 Query: 46 PP---QAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYG 102 P + MA G Q Q L G +S + ++ QR L QQ++ + G Sbjct: 2216 LPLQGSSMGQMAAQMGQLGQMGQPGL----GADSTPNIQQALQQRILQQQQMKQQIGSPG 2271 Query: 103 MASP------------------------GLAAPSLTPPQLATPNLQQFFPQATRQSLLGP 138 +P L+ +P + +P Q P ++ + P Sbjct: 2272 QPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQP 2331 Query: 139 PP---------------VGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVED 183 P + V M S NP++ A TP+R SS+ V D Sbjct: 2332 QPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGD 2391 >gi|119943104 CREB binding protein isoform a [Homo sapiens] Length = 2442 Score = 66.6 bits (161), Expect = 9e-11 Identities = 77/252 (30%), Positives = 107/252 (42%), Gaps = 45/252 (17%) Query: 2 FSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61 + + ++QL QQQQQ QQ QQQQ QQQQ + Q PQ P G PP Sbjct: 2189 YREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGP------GGYPP 2242 Query: 62 ----QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQ 117 QQ Q L LQG+ SM Q A + QL M PGL A S Sbjct: 2243 AMQQQQRMQQHLPLQGS--------SMGQMAAQMGQLG------QMGQPGLGADS----- 2283 Query: 118 LATPNLQQFFPQATRQ-----SLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRK 172 TPN+QQ Q Q +G P PM+P Q LSG+ PQ +S P ++ Sbjct: 2284 --TPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQ-PQ------ASHLPGQQ 2334 Query: 173 DSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP-PCPEDIAKEKRTPAPEPEPCEAS 231 ++S + V + P + ++P +P + P P P ++ + +P P AS Sbjct: 2335 IATSLSNQVRSPA-PVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMAS 2393 Query: 232 ELPAKRLRSSEE 243 + L + E+ Sbjct: 2394 SIDQGHLGNPEQ 2405 Score = 60.8 bits (146), Expect = 5e-09 Identities = 88/353 (24%), Positives = 128/353 (36%), Gaps = 66/353 (18%) Query: 85 LQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVP 144 LQ+A L+++ + + L +P+ PP TP Q PQ T Q P P V Sbjct: 1859 LQQAQLMRRRMATMNTRNVPQQSLPSPTSAPP--GTPTQQPSTPQ-TPQPPAQPQPSPVS 1915 Query: 145 MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPED 204 M+P+ F ART TT + +SQ + PP + EAA + Sbjct: 1916 MSPAGF-------PSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQ 1968 Query: 205 QD----------LPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQ 254 Q +PP + TP + P + ++ P+ PPGQ Q Sbjct: 1969 QQHLYRVNINNSMPPGRTGMG----TPGSQMAPVSLNVPRPNQVSGPVMPSM--PPGQWQ 2022 Query: 255 VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDT--Q 312 PQ Q +P V+ +QAQ + PR+PS Sbjct: 2023 QAPLPQQ--------------------QPMPGLPRPVISMQAQA-AVAGPRMPSVQPPRS 2061 Query: 313 VQPK-LQKQAQTQTSPEHLVLQQKQVQ-----PQLQQEAEPQKQVQPQVHTQAQPSVQPQ 366 + P LQ +T SP QQ+ + PQL Q+ + + QP +QPQ Sbjct: 2062 ISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAK---YVANQPGMQPQ 2118 Query: 367 EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGG 419 +Q +QP H+QP Q ++ A P V PP GG Sbjct: 2119 PGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGV--------PPQQQAMGG 2163 Score = 55.5 bits (132), Expect = 2e-07 Identities = 91/422 (21%), Positives = 147/422 (34%), Gaps = 64/422 (15%) Query: 7 QQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQ 66 + +L+QQQ Q +LQQ QL ++++ + Q SP AP + PQ PQ Sbjct: 1847 KHKLRQQQIQ-HRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQP 1905 Query: 67 PLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQF 126 P Q S ++ + Q G + P PP A +Q Sbjct: 1906 P---AQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQI 1962 Query: 127 FPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSD 186 +A +Q L + M P + + P Q S P S MP S Sbjct: 1963 EREAQQQQHLYRVNINNSMPPGRTGMG--TPGSQMAPVSLNVPRPNQVSGPVMP----SM 2016 Query: 187 PPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK--------RTPAPEPEPCEASELPAKRL 238 PP ++A P+ Q +P P + + R P+ +P + L Sbjct: 2017 PPGQWQQA-----PLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLL 2071 Query: 239 RSSEEPTEKEPPGQLQ--VKAQPQARMTVPKQ------TQTPDLLPE-------ALEAQV 283 R+ + P+ + Q+ +K+ PQ KQ P + P+ ++ Q Sbjct: 2072 RTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQP 2131 Query: 284 LPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQ-------------TQTSPEHL 330 QP + + A +P +P Q L Q Q +P++ Sbjct: 2132 GMHQQPSLQNLNAMQAGVPRPGVP-PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYR 2190 Query: 331 VLQQKQVQPQLQQEAEPQKQVQPQV------------HTQAQPSVQPQEHPPAQVSVQPP 378 + ++Q+ Q QQ+ + Q+Q Q Q H Q Q P +PPA Q Sbjct: 2191 EMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRM 2250 Query: 379 EQ 380 +Q Sbjct: 2251 QQ 2252 Score = 45.8 bits (107), Expect = 2e-04 Identities = 87/378 (23%), Positives = 133/378 (35%), Gaps = 70/378 (18%) Query: 27 QQQLQQQQLLQL-QQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSML 85 Q++L++++ +L +Q + + P P P A +P QP +P NG + Sbjct: 662 QKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPP------------NGPLS 709 Query: 86 QRALLLQQLQGNLRGYGMASPGLAAPSLTP--PQLATPNLQQFFPQATRQSLLGPPPVGV 143 +Q QG + + S G P P+ A+P + + + +G P G+ Sbjct: 710 LPVNRMQVSQG-MNSFNPMSLGNVQLPQAPMGPRAASP-----MNHSVQMNSMGSVP-GM 762 Query: 144 PMNPSQF----NLSG---RNPQKQARTSSSTTP-NRKDSSSQTMPVEDKSDPPEGSEEAA 195 ++PS+ N+ G N QA S P N+ SSS M V Sbjct: 763 AISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSV-------------- 808 Query: 196 EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC-----EASELPAKRLRSSEEPTEKEPP 250 PP +++ + A P P +AS+LP + S P PP Sbjct: 809 --------GMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQS--PLHPTPP 858 Query: 251 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS-T 309 P + T P P + P A P + Q + T +PS T Sbjct: 859 PASTAAGMPSLQHTTP-----PGMTPPQPAAPTQPSTP---VSSSGQTPTPTPGSVPSAT 910 Query: 310 DTQVQPKLQK--QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQE 367 TQ P +Q QAQ P+ V PQ Q+ QP +Q + Sbjct: 911 QTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDN 970 Query: 368 HPPAQVSVQPPEQTHEQP 385 P SV E +QP Sbjct: 971 RVPTPSSVASAETNSQQP 988 Score = 45.8 bits (107), Expect = 2e-04 Identities = 76/354 (21%), Positives = 127/354 (35%), Gaps = 50/354 (14%) Query: 20 LQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASL 79 + Q Q Q L Q Q + Q P VS+G P LN+ G ++ L Sbjct: 784 MAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQL 843 Query: 80 LNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPP 139 + Q L + + P +TPPQ A P +T S G Sbjct: 844 PCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPT-----QPSTPVSSSGQT 898 Query: 140 PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRK----------DSSSQTMPVEDKSDPPE 189 P P + + P QA + TP + SSQ P + PP Sbjct: 899 PTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPG 958 Query: 190 GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 249 A +D + P P +A + T + +P P ++P +++ + + EP Sbjct: 959 TPLSQAAASID-----NRVPTPSSVASAE-TNSQQPGP----DVPVLEMKTETQAEDTEP 1008 Query: 250 -PGQLQVKAQPQARMT------VPKQTQTPDLLPEALEAQVLPRFQPRV-LQVQAQVQSQ 301 PG + K +P++ M + + D+ + E + +P V ++V+ + +S Sbjct: 1009 DPG--ESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESS 1066 Query: 302 TQPRIPSTDTQVQPKLQ-------KQAQTQT-------SPEHLVLQQKQVQPQL 341 + + + QP+ + +QA T PE L +Q V PQL Sbjct: 1067 SNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQ-PVDPQL 1119 Score = 42.7 bits (99), Expect = 0.001 Identities = 62/240 (25%), Positives = 87/240 (36%), Gaps = 66/240 (27%) Query: 6 QQQQLQQQQQQLQQLQQQQLQQQ-------------QLQQQQ-------LLQLQQLLQQS 45 ++Q LQQQQQQ QQ QQQQ QQQ Q QQ Q +Q QQ +QQ Sbjct: 2194 RRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQH 2253 Query: 46 PP---QAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYG 102 P + MA G Q Q L G +S + ++ QR L QQ++ + G Sbjct: 2254 LPLQGSSMGQMAAQMGQLGQMGQPGL----GADSTPNIQQALQQRILQQQQMKQQIGSPG 2309 Query: 103 MASP------------------------GLAAPSLTPPQLATPNLQQFFPQATRQSLLGP 138 +P L+ +P + +P Q P ++ + P Sbjct: 2310 QPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQP 2369 Query: 139 PP---------------VGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVED 183 P + V M S NP++ A TP+R SS+ V D Sbjct: 2370 QPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGD 2429 >gi|17017963 forkhead box P2 isoform I [Homo sapiens] Length = 715 Score = 65.9 bits (159), Expect = 1e-10 Identities = 56/131 (42%), Positives = 62/131 (47%), Gaps = 11/131 (8%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63 QQQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ Q QA QQ Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA------KEQQQQQQ 205 Query: 64 PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAA---PSLTPPQLAT 120 QQ L Q LL LQ+ L LQ +G PG AA SL L+ Sbjct: 206 QQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ--RQGLISIPPGQAALPVQSLPQAGLSP 263 Query: 121 PNLQQFFPQAT 131 +QQ + + T Sbjct: 264 AEIQQLWKEVT 274 Score = 63.2 bits (152), Expect = 1e-09 Identities = 55/134 (41%), Positives = 64/134 (47%), Gaps = 17/134 (12%) Query: 2 FSQQQQQQL-----QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS 56 F ++QQ+QL QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ Q P + Sbjct: 138 FYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 197 Query: 57 RGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPP 116 + QQ QQ L Q Q+ L +QQLQ + GL S+ P Sbjct: 198 KEQQQQQQQQQQLAAQQL--------VFQQQLLQMQQLQQQQHLLSLQRQGLI--SIPPG 247 Query: 117 QLATPNLQQFFPQA 130 Q A P Q PQA Sbjct: 248 QAALP--VQSLPQA 259 Score = 55.1 bits (131), Expect = 3e-07 Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 20/159 (12%) Query: 241 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQ 299 S + ++K+ P Q+ V A MT Q TP + + L+ QVL P+ +LQ Q V Sbjct: 75 SPKSSDKQRPLQVPVSV---AMMT--PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVM 129 Query: 300 SQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQA 359 Q Q Q+Q +KQ E L LQ Q Q Q QQ+ + Q+Q Q Q Q Sbjct: 130 LQQQ--------QLQEFYKKQQ------EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175 Query: 360 QPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQ 398 Q Q Q+ Q P +Q EQ Q Q LA +Q Sbjct: 176 QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/93 (38%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 5 QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61 QQQQ + QQQQLQ+ QQ+QL Q LQQQQ Q QQ QQ Q + Sbjct: 123 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 182 Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQL 94 QQ QQ G + Q+ L QQL Sbjct: 183 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215 Score = 43.9 bits (102), Expect = 6e-04 Identities = 37/136 (27%), Positives = 54/136 (39%), Gaps = 3/136 (2%) Query: 254 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQV---QAQVQSQTQPRIPSTD 310 QV Q + + +Q +P L L+ Q Q + LQ + Q Q Q Sbjct: 97 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 156 Query: 311 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPP 370 Q Q + Q+Q Q Q + QQ+Q Q Q QQ+ P KQ + Q Q Q + Sbjct: 157 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 216 Query: 371 AQVSVQPPEQTHEQPH 386 Q + +Q +Q H Sbjct: 217 FQQQLLQMQQLQQQQH 232 Score = 36.2 bits (82), Expect = 0.13 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 12/126 (9%) Query: 277 EALEA--QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 334 +AL+A Q+L + Q L+ Q ++P + + P++ Q Q + VL Sbjct: 56 QALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSP 115 Query: 335 KQVQPQLQQE----------AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQ 384 +Q+Q LQQ+ E K+ Q Q+H Q Q Q+ Q Q +Q +Q Sbjct: 116 QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175 Query: 385 PHTQPQ 390 Q Q Sbjct: 176 QQQQQQ 181 Score = 33.5 bits (75), Expect = 0.82 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 6/86 (6%) Query: 12 QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAV--SRGLPPQQPQQPLL 69 QQQQ LQ +Q LQQ Q L + +Q P Q P+ +A+ + + PQQ QQ +L Sbjct: 53 QQQQALQAARQLLLQQ---QTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQ-IL 108 Query: 70 NLQGTNSASLLNGSMLQRALLLQQLQ 95 Q + L Q+A++LQQ Q Sbjct: 109 QQQVLSPQQLQALLQQQQAVMLQQQQ 134 Score = 32.0 bits (71), Expect = 2.4 Identities = 45/168 (26%), Positives = 55/168 (32%), Gaps = 20/168 (11%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63 QQ QQ LQQQ QQLQ LQQQQ + LQQ Q + + L QQ Sbjct: 102 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155 Query: 64 PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNL 123 QQ Q Q+ QQ Q + G + QLA L Sbjct: 156 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215 Query: 124 --------------QQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP 157 QQ RQ L+ PP + +G +P Sbjct: 216 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 263 >gi|22538413 forkhead box P2 isoform III [Homo sapiens] Length = 623 Score = 65.9 bits (159), Expect = 1e-10 Identities = 56/131 (42%), Positives = 62/131 (47%), Gaps = 11/131 (8%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63 QQQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ Q QA QQ Sbjct: 60 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA------KEQQQQQQ 113 Query: 64 PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAA---PSLTPPQLAT 120 QQ L Q LL LQ+ L LQ +G PG AA SL L+ Sbjct: 114 QQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ--RQGLISIPPGQAALPVQSLPQAGLSP 171 Query: 121 PNLQQFFPQAT 131 +QQ + + T Sbjct: 172 AEIQQLWKEVT 182 Score = 63.2 bits (152), Expect = 1e-09 Identities = 55/134 (41%), Positives = 64/134 (47%), Gaps = 17/134 (12%) Query: 2 FSQQQQQQL-----QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS 56 F ++QQ+QL QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ Q P + Sbjct: 46 FYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 105 Query: 57 RGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPP 116 + QQ QQ L Q Q+ L +QQLQ + GL S+ P Sbjct: 106 KEQQQQQQQQQQLAAQQL--------VFQQQLLQMQQLQQQQHLLSLQRQGLI--SIPPG 155 Query: 117 QLATPNLQQFFPQA 130 Q A P Q PQA Sbjct: 156 QAALP--VQSLPQA 167 Score = 52.0 bits (123), Expect = 2e-06 Identities = 45/132 (34%), Positives = 58/132 (43%), Gaps = 15/132 (11%) Query: 268 QTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS 326 Q TP + + L+ QVL P+ +LQ Q V Q Q Q+Q +KQ Sbjct: 5 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQ--------QLQEFYKKQQ----- 51 Query: 327 PEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 386 E L LQ Q Q Q QQ+ + Q+Q Q Q Q Q Q Q+ Q P +Q EQ Sbjct: 52 -EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 110 Query: 387 TQPQVSLLAPEQ 398 Q Q LA +Q Sbjct: 111 QQQQQQQLAAQQ 122 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/93 (38%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 5 QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61 QQQQ + QQQQLQ+ QQ+QL Q LQQQQ Q QQ QQ Q + Sbjct: 31 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 90 Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQL 94 QQ QQ G + Q+ L QQL Sbjct: 91 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 123 Score = 46.6 bits (109), Expect = 9e-05 Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 34/241 (14%) Query: 254 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 313 QV Q + + +Q +P L L+ Q Q + LQ + + Q ++ Q Sbjct: 5 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ---EFYKKQQEQLHLQLLQQ 61 Query: 314 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 373 Q + Q+Q Q Q + QQ+Q Q Q QQ+ + Q+Q P + Q Q Q+ A Sbjct: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 121 Query: 374 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQV 433 + +Q + Q Q LL+ ++ ++ +PP + LP Sbjct: 122 QLVFQQQLLQMQQLQQQQHLLSLQRQGLI------SIPPG--------QAALP------- 160 Query: 434 SMEEIQNESACGLDVGECENRAREMPGVWG------AGGSLKVTILQSSDSRAFSTVPLT 487 +Q+ GL E + +E+ GV G L +T SS + + +T + Sbjct: 161 ----VQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKAS 216 Query: 488 P 488 P Sbjct: 217 P 217 Score = 38.9 bits (89), Expect = 0.019 Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%) Query: 250 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 301 P QLQ Q Q + + +Q Q L + L+ Q + Q + Q Q Q Q Q Sbjct: 23 PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 82 Query: 302 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 361 Q Q Q + Q+Q Q Q P +Q+Q Q Q QQ A Q Q Q+ Q Sbjct: 83 QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ- 134 Query: 362 SVQPQEH-----PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 416 +Q Q+H +S+ PP Q + PQ L E + V G+ D Sbjct: 135 -LQQQQHLLSLQRQGLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGI 192 Query: 417 AGGGMEKT 424 GG++ T Sbjct: 193 KHGGLDLT 200 Score = 32.0 bits (71), Expect = 2.4 Identities = 45/168 (26%), Positives = 55/168 (32%), Gaps = 20/168 (11%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63 QQ QQ LQQQ QQLQ LQQQQ + LQQ Q + + L QQ Sbjct: 10 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 63 Query: 64 PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNL 123 QQ Q Q+ QQ Q + G + QLA L Sbjct: 64 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 123 Query: 124 --------------QQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP 157 QQ RQ L+ PP + +G +P Sbjct: 124 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 171 >gi|149999352 forkhead box P2 isoform II [Homo sapiens] Length = 740 Score = 65.9 bits (159), Expect = 1e-10 Identities = 55/130 (42%), Positives = 62/130 (47%), Gaps = 10/130 (7%) Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64 QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ P + QQ Sbjct: 177 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 231 Query: 65 QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAA---PSLTPPQLATP 121 QQ L Q LL LQ+ L LQ +G PG AA SL L+ Sbjct: 232 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ--RQGLISIPPGQAALPVQSLPQAGLSPA 289 Query: 122 NLQQFFPQAT 131 +QQ + + T Sbjct: 290 EIQQLWKEVT 299 Score = 63.2 bits (152), Expect = 1e-09 Identities = 55/134 (41%), Positives = 64/134 (47%), Gaps = 17/134 (12%) Query: 2 FSQQQQQQL-----QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS 56 F ++QQ+QL QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ Q P + Sbjct: 163 FYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 222 Query: 57 RGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPP 116 + QQ QQ L Q Q+ L +QQLQ + GL S+ P Sbjct: 223 KEQQQQQQQQQQLAAQQL--------VFQQQLLQMQQLQQQQHLLSLQRQGLI--SIPPG 272 Query: 117 QLATPNLQQFFPQA 130 Q A P Q PQA Sbjct: 273 QAALP--VQSLPQA 284 Score = 52.8 bits (125), Expect = 1e-06 Identities = 47/143 (32%), Positives = 62/143 (43%), Gaps = 15/143 (10%) Query: 257 AQPQARMTVPKQTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 315 A P + + Q TP + + L+ QVL P+ +LQ Q V Q Q Q+Q Sbjct: 111 AVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQ--------QLQE 162 Query: 316 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSV 375 +KQ E L LQ Q Q Q QQ+ + Q+Q Q Q Q Q Q Q+ Q Sbjct: 163 FYKKQQ------EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 216 Query: 376 QPPEQTHEQPHTQPQVSLLAPEQ 398 P +Q EQ Q Q LA +Q Sbjct: 217 HPGKQAKEQQQQQQQQQQLAAQQ 239 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/93 (38%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 5 QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61 QQQQ + QQQQLQ+ QQ+QL Q LQQQQ Q QQ QQ Q + Sbjct: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 207 Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQL 94 QQ QQ G + Q+ L QQL Sbjct: 208 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240 Score = 46.6 bits (109), Expect = 9e-05 Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 34/241 (14%) Query: 254 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 313 QV Q + + +Q +P L L+ Q Q + LQ + + Q ++ Q Sbjct: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ---EFYKKQQEQLHLQLLQQ 178 Query: 314 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 373 Q + Q+Q Q Q + QQ+Q Q Q QQ+ + Q+Q P + Q Q Q+ A Sbjct: 179 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 238 Query: 374 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQV 433 + +Q + Q Q LL+ ++ ++ +PP + LP Sbjct: 239 QLVFQQQLLQMQQLQQQQHLLSLQRQGLI------SIPPG--------QAALP------- 277 Query: 434 SMEEIQNESACGLDVGECENRAREMPGVWG------AGGSLKVTILQSSDSRAFSTVPLT 487 +Q+ GL E + +E+ GV G L +T SS + + +T + Sbjct: 278 ----VQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKAS 333 Query: 488 P 488 P Sbjct: 334 P 334 Score = 38.9 bits (89), Expect = 0.019 Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%) Query: 250 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 301 P QLQ Q Q + + +Q Q L + L+ Q + Q + Q Q Q Q Q Sbjct: 140 PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 199 Query: 302 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 361 Q Q Q + Q+Q Q Q P +Q+Q Q Q QQ A Q Q Q+ Q Sbjct: 200 QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ- 251 Query: 362 SVQPQEH-----PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 416 +Q Q+H +S+ PP Q + PQ L E + V G+ D Sbjct: 252 -LQQQQHLLSLQRQGLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGI 309 Query: 417 AGGGMEKT 424 GG++ T Sbjct: 310 KHGGLDLT 317 Score = 32.0 bits (71), Expect = 2.4 Identities = 45/168 (26%), Positives = 55/168 (32%), Gaps = 20/168 (11%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63 QQ QQ LQQQ QQLQ LQQQQ + LQQ Q + + L QQ Sbjct: 127 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180 Query: 64 PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNL 123 QQ Q Q+ QQ Q + G + QLA L Sbjct: 181 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240 Query: 124 --------------QQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP 157 QQ RQ L+ PP + +G +P Sbjct: 241 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 288 >gi|38788260 bromodomain PHD finger transcription factor isoform 2 [Homo sapiens] Length = 2903 Score = 65.9 bits (159), Expect = 1e-10 Identities = 49/157 (31%), Positives = 73/157 (46%), Gaps = 11/157 (7%) Query: 258 QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 316 Q Q++++ Q LP A + V P QP+ Q AQ Q QTQP+ P+ QP+ Sbjct: 2364 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2418 Query: 317 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--KQVQPQVHTQAQPSVQPQEHPPAQVS 374 +Q Q + QT + QP Q ++PQ Q QPQ + Q Q V+ Q P+Q Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQS--PSQTR 2476 Query: 375 VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 411 ++P + P Q QV + P+ H L++P Sbjct: 2477 IRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2512 Score = 62.4 bits (150), Expect = 2e-09 Identities = 69/272 (25%), Positives = 104/272 (38%), Gaps = 38/272 (13%) Query: 129 QATRQSLLGPPPVGVPMNPSQFNLSGRNP----QKQARTSSSTTPNRKDSSSQTMPVEDK 184 Q T Q L P V V P Q + P Q+ T +TT +++ T+ Sbjct: 2300 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTT-A 2358 Query: 185 SDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEP 244 + E + P+M +D+ LPP P EA A+ + Sbjct: 2359 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG----------PAEAQPQTAQPSAQPQPQ 2408 Query: 245 TEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL---QVQAQVQSQ 301 T+ + P Q +V+ QP+ V QT +P + +P+V Q Q+ VQ Q Sbjct: 2409 TQPQSPAQPEVQTQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQ 2464 Query: 302 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 361 + R+ S Q +++ +Q SP QQ QVQ Q Q Q+ +Q QP Sbjct: 2465 SPVRVQSPS---QTRIRPSTPSQLSPG----QQSQVQTTTSQPIPIQPHTSLQIPSQGQP 2517 Query: 362 SVQPQ---------EHPPAQVSVQPPEQTHEQ 384 QPQ EH + S+ P E+ Q Sbjct: 2518 QSQPQVVMKHNAVIEHLKQKKSMTPAEREENQ 2549 Score = 43.1 bits (100), Expect = 0.001 Identities = 40/143 (27%), Positives = 50/143 (34%), Gaps = 8/143 (5%) Query: 251 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 310 GQLQ+ Q + P Q L+ A+ + RF L A S T + +T Sbjct: 2303 GQLQLIPQGVTVLPGPGQ----QLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTA 2358 Query: 311 T----QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQ 366 Q Q KL Q Q Q V P Q Q QPQ TQ Q QP+ Sbjct: 2359 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2418 Query: 367 EHPPAQVSVQPPEQTHEQPHTQP 389 +V Q +H QP Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQP 2441 Score = 32.7 bits (73), Expect = 1.4 Identities = 90/469 (19%), Positives = 153/469 (32%), Gaps = 62/469 (13%) Query: 140 PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 199 P+GVP P + PQ++ SS+ P R ++ QT PV ++ E E E R Sbjct: 1970 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 2025 Query: 200 DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 258 +++ E AK++ ++ P S+ P +K + Sbjct: 2026 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 2085 Query: 259 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 308 +M + + +P + F V Q Q+ QVQ + IPS Sbjct: 2086 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2145 Query: 309 --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 350 T T QP+ T+ V+ Q++P + P +Q Sbjct: 2146 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2205 Query: 351 --VQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL 408 V Q Q Q P +V P P Q SL + T + Sbjct: 2206 TPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTP---GQKSLTSATSTSNI--QSSA 2260 Query: 409 EMPPDAVEAGGGMEKTLPEPV-------GTQVSMEEIQNESACGLDVGECENRAREMPGV 461 PP + G ++ T+ + G Q IQ + G G+ + + + + Sbjct: 2261 SQPPRPQQ--GQVKLTMAQLTQLTQGHGGNQGLTVVIQGQ---GQTTGQLQLIPQGVTVL 2315 Query: 462 WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS 521 G G L + + + F PL + + ++T + T+ + + Q Sbjct: 2316 PGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQ------SKL 2369 Query: 522 CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEP 570 Q QD P +G + Q S P P +T+ + P Sbjct: 2370 SPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP----QTQPQSP 2414 Score = 31.6 bits (70), Expect = 3.1 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%) Query: 629 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 681 + D E + E+++ ++E+ +GD EE +D ED+EE E+EE+ Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169 Score = 30.0 bits (66), Expect = 9.0 Identities = 17/60 (28%), Positives = 26/60 (43%) Query: 208 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 267 P P A E+ PAP P P + P LRS + + Q + P+ R++ P+ Sbjct: 9 PKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPR 68 >gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] Length = 825 Score = 65.5 bits (158), Expect = 2e-10 Identities = 67/296 (22%), Positives = 114/296 (38%), Gaps = 27/296 (9%) Query: 138 PPPVGVPMNPSQFNLSGRNPQKQAR----TSSSTTPNRKDSSSQTMPVEDKSDPPEGSEE 193 PP V + Q L P+++AR +++ TP + + P+ ++ E S E Sbjct: 414 PPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAE 473 Query: 194 -----AAEPRMD-TPEDQDLPPCPEDIAKEK----RTPAPEPEPCEASELPAKRLRSSEE 243 A EP D TP + P E A+E ++P E E + + L + E Sbjct: 474 IQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEA 533 Query: 244 PTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA------- 296 P ++ P ++ + P + Q+P ++E L P + A Sbjct: 534 PADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAI 593 Query: 297 QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVH 356 Q+ + T+ +VQP ++A + P +VQP +EA + Q P Sbjct: 594 QLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEE 653 Query: 357 TQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 412 A+ P E PA+V P E+ +V L E+TP+ + + PP Sbjct: 654 APAEVQPPPAEEAPAEVQPPPAEE------APAEVQSLPAEETPIEETLAAVHSPP 703 Score = 48.9 bits (115), Expect = 2e-05 Identities = 70/325 (21%), Positives = 119/325 (36%), Gaps = 58/325 (17%) Query: 172 KDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDL-----PPCPEDIAKEK-------- 218 + S+Q P+E + P EG+ E A +++ P ++ P PE+ +E+ Sbjct: 385 RSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLST 444 Query: 219 --RTPA---------PEPEPCEASELPAK-RLRSSEEPTEKEPPGQLQ---------VKA 257 TPA P P+ A E A+ +L ++ EP E P + + +A Sbjct: 445 AMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEA 504 Query: 258 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD--TQVQP 315 + + + ++T + + E Q+L + + A+ QS + + +VQ Sbjct: 505 HAEVQSPLAEETTAEE---ASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQS 561 Query: 316 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEA---------------EPQKQVQPQVHTQAQ 360 K + +P L LQ + +EA E +VQP +A Sbjct: 562 PSAKGVSIEEAP--LELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAP 619 Query: 361 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPE--QTPVVVHVCGLEMPPDAVEAG 418 VQP A VQPP QP + AP Q P PP A EA Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAP 679 Query: 419 GGMEKTLPEPVGTQVSMEEIQNESA 443 ++ E + ++ + + A Sbjct: 680 AEVQSLPAEETPIEETLAAVHSPPA 704 Score = 46.6 bits (109), Expect = 9e-05 Identities = 47/209 (22%), Positives = 73/209 (34%), Gaps = 24/209 (11%) Query: 168 TPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM--------------DTPEDQDLPPCPED 213 +P+ K S + P+E PP G E AE + P + PP E+ Sbjct: 561 SPSAKGVSIEEAPLE--LQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPA-EE 617 Query: 214 IAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPG--QLQVKAQPQARMTVPKQTQT 271 E + P E P E PA+ E P E +PP + + QP P + Q Sbjct: 618 APAEVQPPPAEEAPAEVQPPPAE-----EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 672 Query: 272 PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV 331 P E Q LP + + + A V S +P+ + V T + Sbjct: 673 PPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIG 732 Query: 332 LQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 360 +V P ++ + + V T+ Q Sbjct: 733 EASAEVSPPPSEQTPEDEALVENVSTEFQ 761 Score = 45.4 bits (106), Expect = 2e-04 Identities = 91/450 (20%), Positives = 160/450 (35%), Gaps = 102/450 (22%) Query: 153 SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPP-----------------EGS--EE 193 + +P+ Q T+S+ +K+ S + E K PP EGS ++ Sbjct: 192 ASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKK 251 Query: 194 AAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASEL-------------------- 233 A ++ P + P + E+ T EP P E + + Sbjct: 252 VASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAE 311 Query: 234 --------PAKRLRSSEEPTEKEPPG-------QLQVKAQPQARMTVPKQTQTPDLLPEA 278 PA+ E P E +PP +L + P + P + ++LP Sbjct: 312 NSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPP 371 Query: 279 LE----AQVL-----PRFQPRVLQVQ------------AQVQSQTQPRIPSTDTQVQPKL 317 E ++L P Q ++VQ A+V+ P + T VQP L Sbjct: 372 AEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVE---PPTVEETLADVQPLL 428 Query: 318 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ---------PQEH 368 ++A + + E L L P + E Q + P+ T + S + P + Sbjct: 429 PEEAPREEARE-LQLSTAMETPAEEAPTEFQSPL-PKETTAEEASAEIQLLAATEPPADE 486 Query: 369 PPAQVSVQPPEQTH-EQPHTQPQVSL----LAPEQTPVVVHVCGLEMPPDAVEAGGGMEK 423 PA+ E+T E+ H + Q L A E + + + +E P D E + Sbjct: 487 TPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPAD--ETPAEAQS 544 Query: 424 TLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG--VWGAGGSLKVTILQSSDSRAF 481 L E + + E+Q+ SA G+ + E + G S + +L ++++ A Sbjct: 545 PLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASA- 603 Query: 482 STVPLTPVPRPSDSVSS---TPAATSTPSK 508 P P P++ + P A P++ Sbjct: 604 EEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 633 Score = 42.0 bits (97), Expect = 0.002 Identities = 58/256 (22%), Positives = 107/256 (41%), Gaps = 28/256 (10%) Query: 206 DLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTV 265 ++PP E + KE++T E E S + +S E+ + + G++ P+ + Sbjct: 144 NIPPV-EKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQ--- 199 Query: 266 PKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 325 P ++ + + + + V + + + + +P Q ++K A + Sbjct: 200 PATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVV--QEGSAVKKVASAEI 257 Query: 326 SPEHLVLQQKQVQPQLQQEAEPQKQVQP--QVHTQAQPSVQPQEHPPAQ---------VS 374 P ++QP L +EA + + +P + H Q QPS +E P A+ V Sbjct: 258 EPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPST--EETPDAEAATAVAENSVK 315 Query: 375 VQPPEQTHEQPHTQPQVSLLAP--EQTPVVVHVCGLEMPPDAVEAGG--GMEKTLPEPVG 430 VQPP E P + + P E++P V + + +PP A E+ + LP P Sbjct: 316 VQPP-PAEEAPLVEFPAEIQPPSAEESPSVELLAEI-LPPSAEESPSEEPPAEILPPPAE 373 Query: 431 TQVSME---EIQNESA 443 S+E EI++ SA Sbjct: 374 KSPSVELLGEIRSPSA 389 >gi|221139761 zinc finger protein 853 [Homo sapiens] Length = 659 Score = 63.9 bits (154), Expect = 6e-10 Identities = 86/345 (24%), Positives = 127/345 (36%), Gaps = 41/345 (11%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 M QQQ Q Q Q+QQ Q QQ+QLQ QQ Q+QQ+LQ Q+ LQQ + L L Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLAT 120 QQ Q LQ Q+ LLL Q QG L+ + QL Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQ--------QQAQLQQ 264 Query: 121 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 180 L+Q Q +Q LL Q+Q + + + Sbjct: 265 QLLEQQQAQLQQQLLL---------------------QQQEQLQQQQQQQLLQQQQEQLQ 303 Query: 181 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 240 + PP EE E+ +L P D+ E+ E EL ++ + Sbjct: 304 QQQLQPPPLEPEE--------EEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQR 355 Query: 241 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 300 + +E QL+ + + Q + ++ Q +L P L AQ Q + VQ ++Q Sbjct: 356 QLQLKLQEELQQLEQQLEQQQQQLEQQEVQL-ELTPVELGAQ-QQEVQLELTPVQPELQL 413 Query: 301 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA 345 + P V A P ++V+Q+ V P + A Sbjct: 414 ELVPAAGGGGAAVPG--APAAVVVAPPGYVVVQELMVLPAVAAPA 456 Score = 63.5 bits (153), Expect = 7e-10 Identities = 74/256 (28%), Positives = 117/256 (45%), Gaps = 25/256 (9%) Query: 147 PSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQD 206 P LSG + +++ P ++SS Q V S P SE A E R P ++ Sbjct: 37 PGPDTLSGGSGGSESQEEEE--PQERNSSPQRPAV---SAPVGASEIAEETR---PGQRE 88 Query: 207 LPPCPEDIAKEKRTPAPEPEPC-EASELPAKRLRSSEEPTEKEPPGQLQV-KAQPQARMT 264 L + + ++ P P+ +P E + P L ++P + GQ Q+ + Q + + Sbjct: 89 L-----QLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQD---GQQQLSQLQQEKHQS 140 Query: 265 VPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQ 324 V Q P+L + Q+ QP+ +Q Q ++Q Q Q ++ + Q Q LQ+Q Q Q Sbjct: 141 VHHQELKPELQLMHQQQQL----QPQQVQEQQRLQQQ-QEQLQTQQAQEQQVLQQQEQLQ 195 Query: 325 TS-PEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEH-PPAQVSVQPPEQTH 382 E +LQQ+Q Q Q QQ + Q+Q+Q Q Q Q +Q Q+ Q Q +Q Sbjct: 196 QQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLL 255 Query: 383 EQPHTQPQVSLLAPEQ 398 +Q Q Q LL +Q Sbjct: 256 QQQQAQLQQQLLEQQQ 271 Score = 57.0 bits (136), Expect = 7e-08 Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 5/185 (2%) Query: 211 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL--QVKAQPQARMTVPKQ 268 P+ + +++R + + + L+ E+ ++ QL Q + Q Q + + +Q Sbjct: 161 PQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ 220 Query: 269 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 328 Q + + Q+ + Q +LQ Q Q+Q Q + Q+Q +L +Q Q Q + Sbjct: 221 EQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL---LQQQQAQLQQQLLEQQQAQLQQQ 277 Query: 329 HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 388 L+ QQ+Q+Q Q QQ+ Q+Q Q Q P ++P+E ++ + P + EQ Q Sbjct: 278 LLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQ 337 Query: 389 PQVSL 393 + L Sbjct: 338 QRQEL 342 Score = 53.9 bits (128), Expect = 6e-07 Identities = 65/261 (24%), Positives = 109/261 (41%), Gaps = 10/261 (3%) Query: 147 PSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ- 205 P + N S + P A +S + + ++ PE ++ ++ P+ Sbjct: 57 PQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHL 116 Query: 206 DLPPCPEDIAKEKRTPAPEPEPCEASELPAK-RLRSSEEPTEKEPPG-QLQVKAQPQARM 263 +L P+ +++ + + + K L+ + + +P Q Q + Q Q Sbjct: 117 ELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQ 176 Query: 264 TVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQT 323 +Q Q +L + + Q + Q + Q Q Q+Q Q Q Q Q Q+Q Q Sbjct: 177 LQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ-QLLQQQEQLQQQQFQQQQEQL 235 Query: 324 QTSPEHLVLQQK-QVQPQL--QQEAEPQKQV--QPQVHTQAQPSVQPQEHPPAQVSVQPP 378 Q + L+LQQ+ Q+Q QL QQ+A+ Q+Q+ Q Q Q Q +Q QE Q Q Sbjct: 236 QQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLL 295 Query: 379 EQTHEQ-PHTQPQVSLLAPEQ 398 +Q EQ Q Q L PE+ Sbjct: 296 QQQQEQLQQQQLQPPPLEPEE 316 Score = 50.8 bits (120), Expect = 5e-06 Identities = 110/434 (25%), Positives = 157/434 (36%), Gaps = 94/434 (21%) Query: 4 QQQQQQLQQQQQQLQQLQQQQ----LQQQQLQ--QQQLLQLQQLLQQS------PPQAPL 51 Q +QQ QQQ Q +QLQQ Q LQQQ Q QQQL QLQQ QS P+ L Sbjct: 93 QLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQL 152 Query: 52 --------PMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRAL----LLQQLQGNLR 99 P V QQ Q+ L Q L LQ+ + LLQQ Q L+ Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212 Query: 100 GYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR-NPQ 158 + QL QQ Q +Q L + Q L + Q Sbjct: 213 QQQLLQ--------QQEQLQQQQFQQQQEQLQQQQQL-------LLLQQQGQLQQQLLQQ 257 Query: 159 KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 218 +QA+ ++ Q + ++ + E + Q L E + +++ Sbjct: 258 QQAQLQQQLLEQQQAQLQQQLLLQQQ-----------EQLQQQQQQQLLQQQQEQLQQQQ 306 Query: 219 RTPAP-EPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPE 277 P P EPE E EL L + +E+E Q Q Sbjct: 307 LQPPPLEPEEEEEVEL---ELMPVDLGSEQELEQQRQ----------------------- 340 Query: 278 ALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQV 337 LE Q Q Q+Q ++Q + Q + Q Q Q++ Q + +P L QQ++V Sbjct: 341 ELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEV 400 Query: 338 QPQLQQEAEPQKQVQPQVHTQAQPSV----QPQEHPPAQVSVQPPEQTHEQPHTQPQVSL 393 Q +L VQP++ + P+ PA V V PP Q ++ + Sbjct: 401 QLEL-------TPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQ-----ELMV 448 Query: 394 LAPEQTPVVVHVCG 407 L P VV + G Sbjct: 449 LPAVAAPAVVAIPG 462 Score = 46.2 bits (108), Expect = 1e-04 Identities = 82/412 (19%), Positives = 153/412 (37%), Gaps = 93/412 (22%) Query: 12 QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNL 71 Q++ QLQQL+QQ QQQ Q +QL Q P P + P Q QQ L L Sbjct: 86 QRELQLQQLEQQPEPQQQPQHEQL------------QQPQPHLELQQQPQQDGQQQLSQL 133 Query: 72 QGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQAT 131 Q S+ + Q+L+ P+L + QQ Sbjct: 134 QQEKHQSVHH----------QELK--------------------PELQLMHQQQ------ 157 Query: 132 RQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGS 191 + P Q R Q+Q + + ++ Q + +++ Sbjct: 158 ------------QLQPQQVQEQQRLQQQQEQLQT-----QQAQEQQVLQQQEQLQQQVQE 200 Query: 192 EEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPG 251 ++ + + + + Q L E + +++ E +L+ ++ + G Sbjct: 201 QQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQE------------QLQQQQQLLLLQQQG 248 Query: 252 QLQVK------AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPR 305 QLQ + AQ Q ++ +Q Q L + Q+ + Q ++LQ Q + Q Q + Sbjct: 249 QLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQ 308 Query: 306 IPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE---PQKQVQ-------PQV 355 P + + + +++ + L+Q++ + + QQE E Q+Q+Q Q+ Sbjct: 309 PPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQL 368 Query: 356 HTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCG 407 Q + Q E Q+ + P E +Q Q +++ + PE +V G Sbjct: 369 EQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAG 420 >gi|91208418 transcription elongation regulator 1 isoform 2 [Homo sapiens] Length = 1077 Score = 63.9 bits (154), Expect = 6e-10 Identities = 74/260 (28%), Positives = 94/260 (36%), Gaps = 33/260 (12%) Query: 137 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 196 GPPP+ P P F + R P R P D + MP PP G Sbjct: 42 GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96 Query: 197 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK 256 P P +PP P + P P A PA K P G++ Sbjct: 97 PPFMPPPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150 Query: 257 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 316 AR T+ PD + ++++ P +L QAQVQ+Q Q + Q Q + Sbjct: 151 ---NARTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQAQ-----AQAQAQ 196 Query: 317 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ 376 Q QAQ Q Q Q Q Q Q +A+ Q Q Q Q QAQ Q Q Q VQ Sbjct: 197 AQAQAQAQA--------QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQ 248 Query: 377 PPEQTHEQPHTQPQVSLLAP 396 Q + P S AP Sbjct: 249 AQVQAQAVGASTPTTSSPAP 268 Score = 55.1 bits (131), Expect = 3e-07 Identities = 87/420 (20%), Positives = 140/420 (33%), Gaps = 41/420 (9%) Query: 26 QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84 + ++ +L QQ + AP P AV RG PP +P P ++G Sbjct: 10 ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPP------ 63 Query: 85 LQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQ--FFPQATRQSLLGPPPVG 142 + + P + P PP + P+LQ+ F P PPP G Sbjct: 64 --------RPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM---PPPPG 112 Query: 143 VPMNPSQFNLSGRN----PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPR 198 + P ++ P + + TP+ K E P+G + + Sbjct: 113 MMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSE 172 Query: 199 MDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 258 + TP + + A +A + A+ ++ + + Q Q +AQ Sbjct: 173 L-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQAQAQAQAQAQAQAQAQAQ 230 Query: 259 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ 318 QA+ Q Q + ++AQ + P V + T PS+ T Sbjct: 231 AQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTAT 290 Query: 319 KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPP 378 AQT ++P Q Q A P V T PQ HP PP Sbjct: 291 SVAQTVSTP----TTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHP----QTLPP 342 Query: 379 EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGG---GMEKTLPEPVGTQVSM 435 PH+ PQ + P PV+V + +P + G GM + + QV++ Sbjct: 343 ----AVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAI 398 Score = 41.2 bits (95), Expect = 0.004 Identities = 76/302 (25%), Positives = 105/302 (34%), Gaps = 50/302 (16%) Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62 Q Q Q Q Q Q Q Q Q Q Q+Q Q Q+Q Q + S P P AVS Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277 Query: 63 QPQQPLLNLQGTNSASLLNGSMLQR-ALLLQQLQGNLRGYGMASPGLA----APSLTPPQ 117 P T S + S+ Q + Q Q +A+P ++ AP+ TP Q Sbjct: 278 TP-------SSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQ 330 Query: 118 LATPNLQQFFPQATRQSLLGP------------PPVGVPMNPSQFNLSG----------- 154 Q P A S+ P PP VP+ L G Sbjct: 331 TVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVP 390 Query: 155 -RNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPED-QDLPPCPE 212 +PQ S +T S T + E + P++ ++ E Sbjct: 391 MIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEE 450 Query: 213 DIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEKEPPGQLQVKAQPQARMT 264 I + + P+ EP P E E P K ++ EE TE+E Q KA+P A Sbjct: 451 KIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQ---KAKPVATAP 507 Query: 265 VP 266 +P Sbjct: 508 IP 509 >gi|21327715 transcription elongation regulator 1 isoform 1 [Homo sapiens] Length = 1098 Score = 63.9 bits (154), Expect = 6e-10 Identities = 74/260 (28%), Positives = 94/260 (36%), Gaps = 33/260 (12%) Query: 137 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 196 GPPP+ P P F + R P R P D + MP PP G Sbjct: 42 GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96 Query: 197 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK 256 P P +PP P + P P A PA K P G++ Sbjct: 97 PPFMPPPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150 Query: 257 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 316 AR T+ PD + ++++ P +L QAQVQ+Q Q + Q Q + Sbjct: 151 ---NARTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQAQ-----AQAQAQ 196 Query: 317 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ 376 Q QAQ Q Q Q Q Q Q +A+ Q Q Q Q QAQ Q Q Q VQ Sbjct: 197 AQAQAQAQA--------QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQ 248 Query: 377 PPEQTHEQPHTQPQVSLLAP 396 Q + P S AP Sbjct: 249 AQVQAQAVGASTPTTSSPAP 268 Score = 55.1 bits (131), Expect = 3e-07 Identities = 109/556 (19%), Positives = 188/556 (33%), Gaps = 82/556 (14%) Query: 26 QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84 + ++ +L QQ + AP P AV RG PP +P P ++G Sbjct: 10 ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPP------ 63 Query: 85 LQRALLLQQLQGNLRGYGMASPGLAAPSLTPPQLATPNLQQ--FFPQATRQSLLGPPPVG 142 + + P + P PP + P+LQ+ F P PPP G Sbjct: 64 --------RPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM---PPPPG 112 Query: 143 VPMNPSQFNLSGRN----PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPR 198 + P ++ P + + TP+ K E P+G + + Sbjct: 113 MMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSE 172 Query: 199 MDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 258 + TP + + A +A + A+ ++ + + Q Q +AQ Sbjct: 173 L-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQAQAQAQAQAQAQAQAQAQ 230 Query: 259 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ 318 QA+ Q Q + ++AQ + P V + T PS+ T Sbjct: 231 AQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTAT 290 Query: 319 KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPP 378 AQT ++P Q Q A P V T PQ HP PP Sbjct: 291 SVAQTVSTP----TTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHP----QTLPP 342 Query: 379 EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEI 438 PH+ PQ + P PV+V PP V G +P P+ M+ + Sbjct: 343 ----AVPHSVPQPTTAIPAFPPVMV-------PPFRVPLPG-----MPIPLPGVAMMQIV 386 Query: 439 QNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSS 498 +C + +PG+ P+ P+ P ++++ Sbjct: 387 ----SCPYVKTVATTKTGVLPGM---------------------APPIVPMIHPQVAIAA 421 Query: 499 TPA--ATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLL--S 554 +PA A +T + ++ K + + + +PQ + +++ + + S Sbjct: 422 SPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPS 481 Query: 555 LLPVPRDVLETEDEEP 570 P+P +ETE+E+P Sbjct: 482 EEPLP---METEEEDP 494 Score = 33.5 bits (75), Expect = 0.82 Identities = 46/154 (29%), Positives = 58/154 (37%), Gaps = 21/154 (13%) Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62 Q Q Q Q Q Q Q Q Q Q Q+Q Q Q+Q Q + S P P AVS Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277 Query: 63 QPQQPLLNLQGTNSASLLNGSMLQR-ALLLQQLQGNLRGYGMASPGLA----APSLTPPQ 117 P T S + S+ Q + Q Q +A+P ++ AP+ TP Q Sbjct: 278 TP-------SSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQ 330 Query: 118 LATPNLQQFFPQATRQSLLGP-------PPVGVP 144 Q P A S+ P PPV VP Sbjct: 331 TVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVP 364 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 63.5 bits (153), Expect = 7e-10 Identities = 83/367 (22%), Positives = 137/367 (37%), Gaps = 75/367 (20%) Query: 106 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR---------- 155 P P + PP+ P + P A + PP VP P + + Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKPEA---PPPKVPEAPKEVVPEKKVPVPPPKKPE 10547 Query: 156 -NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEE-----------AAEPRMDTPE 203 P K + P +K + +P + +S PPE E AA P+ Sbjct: 10548 VPPTKVPEVPKAAVPEKK--VPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVT 10605 Query: 204 DQDLPPCPEDIAKEKRTPAPEPE-----PCEASELPAKRLRSS----------------- 241 +P P+++ EK+ P P P+ P + E+P + Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV 10665 Query: 242 -EEPTE---KEPPGQLQVKAQPQA--RMTVPKQTQTPDLLPEALEAQVLPRFQP-RVLQV 294 EEP E +EPP ++ + +P A ++TVP + P+ A+ A+ P P +V +V Sbjct: 10666 FEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAK-KPELPPVKVPEV 10724 Query: 295 QAQVQSQTQ-----PRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQK 349 +V + + P+ P P++ K+ V+ +K+V + E P K Sbjct: 10725 PKEVVPEKKVPLVVPKKPEAPPAKVPEVPKE----------VVPEKKVAVPKKPEVPPAK 10774 Query: 350 QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV-VVHVCGL 408 P+V + +P P + PPE E P+ + E+ PV V Sbjct: 10775 --VPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEP 10832 Query: 409 EMPPDAV 415 E+PP AV Sbjct: 10833 EVPPPAV 10839 Score = 58.5 bits (140), Expect = 2e-08 Identities = 54/248 (21%), Positives = 101/248 (40%), Gaps = 22/248 (8%) Query: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216 P+K P K + V + PE P+ + P +P P+ Sbjct: 9954 PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013 Query: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP-PGQLQVKAQPQARMTVPKQTQTPDLL 275 E++ P P P+ EA + P +K P P +V+A P VPK+ L+ Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKK-----LI 10068 Query: 276 PEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQK 335 PE + +P+ +V+A P++P V + + + E ++ ++ Sbjct: 10069 PEEKKPTPVPK------KVEA-----PPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEE 10117 Query: 336 QVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQ-THEQPHTQPQVSLL 394 +V P+ ++ +++V P+ + + + +E PP + V P E+ E+ P+ +L Sbjct: 10118 EVLPEEEEVLPEEEEVLPE---EEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVL 10174 Query: 395 APEQTPVV 402 PE P V Sbjct: 10175 -PEVKPKV 10181 Score = 51.6 bits (122), Expect = 3e-06 Identities = 75/330 (22%), Positives = 130/330 (39%), Gaps = 46/330 (13%) Query: 105 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGP-----PPVGVPMNPSQFNLSGRNPQK 159 +P + A P + P + + + L+ P PP VP P + P+K Sbjct: 10706 APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV-----PEK 10760 Query: 160 Q-ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 218 + A P K PV ++ E A P + E+ + E+IA E+ Sbjct: 10761 KVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEE 10820 Query: 219 RTPAP-----EPE--PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQT 271 P P EPE P E P K + + P K+P + +P+ + PK Sbjct: 10821 EKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPR 10880 Query: 272 P----------DLLPEALEAQVLPRFQ-PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQ 320 P D+ + + + +P+ + P QV +V+ T ++P + +V+ KL + Sbjct: 10881 PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVE-LTPLKVPGGEKKVR-KLLPE 10938 Query: 321 AQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV-SVQPPE 379 + + E ++ K V + +E EP +V+P+ + + P+ PP V V+ P Sbjct: 10939 RKPEPKEEVVL---KSVLRKRPEEEEP--KVEPKKLEKVKKPAVPEPPPPKPVEEVEVPT 10993 Query: 380 QTHEQ---------PHTQPQVSLLAPEQTP 400 T + P +P + L APE P Sbjct: 10994 VTKRERKIPEPTKVPEIKPAIPLPAPEPKP 11023 Score = 51.2 bits (121), Expect = 4e-06 Identities = 57/210 (27%), Positives = 85/210 (40%), Gaps = 14/210 (6%) Query: 222 APEPEPCEASELPAKRLRSSEEPTE-KEPPGQLQVKAQPQARMT-VPKQTQTPDLLPEAL 279 A E E E + P K SE+ K+PP ++ + +P A++ VPK+ + + Sbjct: 10427 AEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPE 10486 Query: 280 EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 339 E +V P P VL + V + P P+ + P +A + PE V V P Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKV----PVPP 10542 Query: 340 QLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL-LAPEQ 398 + E P K P+V A P + E P + PPE P+ + AP + Sbjct: 10543 PKKPEVPPTK--VPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPK 10600 Query: 399 TPVVVHVCGLEMPPDAVEAGGGMEKTLPEP 428 P V V E P + V EK +P P Sbjct: 10601 KPEVTPVKVPEAPKEVVP-----EKKVPVP 10625 Score = 46.2 bits (108), Expect = 1e-04 Identities = 63/302 (20%), Positives = 118/302 (39%), Gaps = 58/302 (19%) Query: 139 PPVGVPMNPSQFNLSGRNPQ---KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAA 195 PP VP P + + P K+ P +++ PV P+ E Sbjct: 10056 PPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKRE------PVPVPVALPQEEEVLF 10109 Query: 196 EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC--EASELPAKRLRSSEEPTEKEPPGQL 253 E + PE++ LP E++ E+ PE E E E+P P E+E P + Sbjct: 10110 EEEI-VPEEEVLPE-EEEVLPEEEEVLPEEEEVLPEEEEIP---------PEEEEVPPEE 10158 Query: 254 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQ---PRIPSTD 310 + P+ VP++ P++ P+ +P + +V + + + + + ++P Sbjct: 10159 EY--VPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVP 10216 Query: 311 TQVQPK---LQKQ-----AQTQTSPEHLVLQQKQV---QPQLQQEAEPQKQVQPQVHTQA 359 +V+ K L K+ + PE + ++++ P +++ E P+V +A Sbjct: 10217 KKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKA 10276 Query: 360 QPSV-----QPQEHPPAQVSVQ---------------PPEQTHEQPHTQPQVSLLAPEQT 399 P + E PPA+VS + PP + E P P+ +L P++ Sbjct: 10277 VPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKE 10336 Query: 400 PV 401 V Sbjct: 10337 AV 10338 Score = 46.2 bits (108), Expect = 1e-04 Identities = 79/369 (21%), Positives = 148/369 (40%), Gaps = 66/369 (17%) Query: 115 PPQLATPNLQQFFPQATRQSLLGPP-PVGVPMNPSQFNLSGRN---PQKQARTSSST--T 168 P + P ++F P+ + P PV P+ + ++ + P+K+ + Sbjct: 10156 PEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEV 10215 Query: 169 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK----------EK 218 P + + +P E++ P E +EE E + E + PP E++ + +K Sbjct: 10216 PKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKK 10275 Query: 219 RTP-APEPEPCEASELPAKRLRSSEE-----PTEKE--PPGQLQ--VKAQPQARMTVPKQ 268 P AP P P + PAK + E P +K+ PP ++ K P+ ++ VPK+ Sbjct: 10276 AVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKK 10335 Query: 269 TQTPDLLPE-ALEAQVLPRFQPRVL---QVQAQVQSQTQPRIPSTDT--QVQPKLQ---- 318 P LE +V F+ V+ +++ +V IP + +V+ + Sbjct: 10336 EAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEF 10395 Query: 319 -------KQAQTQTSPEHL---------VLQQKQVQPQLQQEAEPQ-KQVQPQVHTQAQP 361 K Q + EH V + ++V+ + +A P+ ++ ++ +P Sbjct: 10396 HEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKP 10455 Query: 362 --SVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGG 419 V P++ PPA+V P + E+ P+ + P + P V +PP V Sbjct: 10456 PTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEV-------LPPKEVVP-- 10506 Query: 420 GMEKTLPEP 428 EK +P P Sbjct: 10507 --EKKVPVP 10513 Score = 46.2 bits (108), Expect = 1e-04 Identities = 79/344 (22%), Positives = 132/344 (38%), Gaps = 81/344 (23%) Query: 139 PPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVED---KSDPPEGSEEAA 195 PP VP P + L + + S P + + P E+ + + P E Sbjct: 10771 PPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEE 10830 Query: 196 EPRMDTPEDQDLPPCPEDIAKEKRTP------AP---EPEPCEASELPAKRLRSSEEPTE 246 EP + P +P P+ I EK+ P AP EPEP + E P +L+ P Sbjct: 10831 EPEVPPPA---VPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKP--KLKPRPPPPP 10885 Query: 247 KEPPGQ------LQVKAQPQARMTVPKQTQTPDLL----------------------PEA 278 PP + Q+KA P+ + VP++ Q P+ + PE Sbjct: 10886 PAPPKEDVKEKIFQLKAIPKKK--VPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEP 10943 Query: 279 LEAQVL------------PRFQPRVLQ-VQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 325 E VL P+ +P+ L+ V+ + P P + +V P + K+ + Sbjct: 10944 KEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEV-PTVTKRERKIP 11002 Query: 326 SPEHLVLQQKQVQPQLQQEA-EPQKQVQPQVHTQAQPSVQPQEHP---PAQVSVQPPEQT 381 P + +++P + A EP+ + + +V T P V+P+ P P V V + Sbjct: 11003 EPTKV----PEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAE 11058 Query: 382 HEQPH---TQPQVSLL-APEQTPVVVHV--------CGLEMPPD 413 + P +P+ + P++TP + G E PPD Sbjct: 11059 AKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPD 11102 Score = 42.0 bits (97), Expect = 0.002 Identities = 45/262 (17%), Positives = 105/262 (40%), Gaps = 34/262 (12%) Query: 198 RMDTPEDQDLPPCPEDIAKEKRTPAPEP---------------EPCEASELPAKRLRSSE 242 +++ P +P P+ I EK+ PAP P +P ++P K ++ E Sbjct: 9571 KIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEE 9630 Query: 243 EPTEKEPPGQLQVKAQPQARMTVPKQTQTPD---------LLPEALEAQVLPRFQ----P 289 K +Q+ + + + V K+ P +PE ++ P+ + Sbjct: 9631 PLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPA 9690 Query: 290 RVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQK 349 +V + + +V + + I + + QP +++ + L+++ V Q ++E E + Sbjct: 9691 KVTEFRKRVVKEEKVSIEAPKREPQP-IKEVTIMEEKERAYTLEEEAVSVQREEEYEEYE 9749 Query: 350 QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQ--VSLLAPEQTPVVVHVCG 407 + + + +P+ + ++ + + HE+ T+P+ + + + PV Sbjct: 9750 EYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKP-- 9807 Query: 408 LEMPPDAVEAGGGMEKTLPEPV 429 + PP V E+ +P P+ Sbjct: 9808 -KAPPAKVLKKAVPEEKVPVPI 9828 Score = 41.6 bits (96), Expect = 0.003 Identities = 53/265 (20%), Positives = 101/265 (38%), Gaps = 23/265 (8%) Query: 179 MPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE----PCEASELP 234 +P+ K +PP + P+ PE++ P P+ KE P PE P ++P Sbjct: 9303 VPIPKKVEPP-APKVPEVPKKPVPEEKKPVPVPK---KEPAAPPKVPEVPKKPVPEEKIP 9358 Query: 235 AKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV------LPRFQ 288 + E P K P Q V + + + ++ P +PE + +V +PR + Sbjct: 9359 VPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKE 9418 Query: 289 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA---QTQTSPEHLVLQQKQVQPQLQQEA 345 V +V + + +P V + K+A + + S + +V +++ V + A Sbjct: 9419 EEV-PPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFA 9477 Query: 346 EPQKQVQPQVHTQAQPS-VQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVV- 403 PQ+ + A+ +E +SV E+ E+ + + E VV Sbjct: 9478 VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVE 9537 Query: 404 ---HVCGLEMPPDAVEAGGGMEKTL 425 H+ + + E EK + Sbjct: 9538 EKLHIISKRVEAEPAEVTERQEKKI 9562 Score = 40.4 bits (93), Expect = 0.007 Identities = 54/244 (22%), Positives = 99/244 (40%), Gaps = 40/244 (16%) Query: 224 EPEPCEASELPAKRLRSSEEPTE-KEPPGQLQVKAQPQARMTVP---KQTQTPDLLPEA- 278 EPE +P K + PT+ K PP ++ KA P+ ++ VP K P +PE Sbjct: 9788 EPE----KPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEP 9843 Query: 279 -------LEAQVLPRFQPRVLQVQAQVQSQ-----TQPRIPSTDTQVQPKLQ-KQAQTQT 325 + + R + +V + A+V + + ++P +V P ++ + + Sbjct: 9844 KKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKEL 9903 Query: 326 SPEHLVLQQK---QVQPQLQQEAEPQKQVQPQVHTQAQ---------PSVQPQEHPPAQV 373 PE + +++ V+ L +E E + + T+ + P V + P + Sbjct: 9904 EPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKK 9963 Query: 374 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA----VEAGGGMEKTLPEPV 429 V P++ P P+V E+ PV++ E PP A V E+ +P PV Sbjct: 9964 PVPVPKKKEAPPAKVPEVPKKPEEKVPVLIP--KKEKPPPAKVPEVPKKPVPEEKVPVPV 10021 Query: 430 GTQV 433 +V Sbjct: 10022 PKKV 10025 Score = 37.4 bits (85), Expect = 0.057 Identities = 41/227 (18%), Positives = 87/227 (38%), Gaps = 10/227 (4%) Query: 163 TSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAA---EPRMDTPEDQDLPPCPEDIAKEKR 219 T S R D M + + + EG EPR + +L ++I E + Sbjct: 8874 TESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELK 8933 Query: 220 TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL 279 P +P + + E P PP L + P+ + PK+ + + Sbjct: 8934 PPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPT-PEEKKPPPKRIEVTKKAVKKD 8992 Query: 280 EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 339 +V+ + P+ + + ++ + P T + K + + E + + + Sbjct: 8993 AKKVVAK--PKEMTPREEIVKKPPP----PTTLIPAKAPEIIDVSSKAEEVKIMTITRKK 9046 Query: 340 QLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 386 ++Q+E E + + VH + + ++ E P ++ V+P + EQP+ Sbjct: 9047 EVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPY 9093 Score = 36.2 bits (82), Expect = 0.13 Identities = 66/340 (19%), Positives = 124/340 (36%), Gaps = 57/340 (16%) Query: 189 EGSEEAAEPRMDTPEDQDLPPCPEDI---AKEKRTPAPEPE---PCEASELPAKRLRSSE 242 EG +E E + +++++ +++ + E++ PA PE P + + E Sbjct: 9131 EGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIE 9190 Query: 243 EPTEKEPPGQLQVKAQPQ-ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 301 + + + ++QV P+ ++ VP++ + E +E +V P V + + + Sbjct: 9191 KTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKV-----PAVHTKKMVISEE 9245 Query: 302 TQPRIPSTDTQVQ---PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQ 358 T+ +V P++QK+ T+ V K+V+P + P+K +V Sbjct: 9246 KMFFASHTEEEVSVTVPEVQKEIVTEEKIH--VAISKRVEPPPKVPELPEKPAPEEVAPV 9303 Query: 359 AQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAG 418 P P + P ++P P+ AP + P E+P V Sbjct: 9304 PIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVP--------EVPKKPVP-- 9353 Query: 419 GGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDS 478 E+ +P PV + + A V E + G K+TI+ + Sbjct: 9354 ---EEKIPVPVA--------KKKEAPPAKVPEVQK---------GVVTEEKITIVTQREE 9393 Query: 479 RAFSTVP----------LTPVPRPSDSVSSTPAATSTPSK 508 VP PVPR + V P + P K Sbjct: 9394 SPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKK 9433 Score = 35.8 bits (81), Expect = 0.16 Identities = 32/175 (18%), Positives = 72/175 (41%), Gaps = 14/175 (8%) Query: 211 PEDIAKEKRTPAPEPEPC-EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 269 PE+I P P P E + P KR+ +++ +K+ + + R + K+ Sbjct: 8954 PEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKP 9013 Query: 270 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 329 P L +P P ++ V ++ + I + ++QK+ + + Sbjct: 9014 PPPTTL--------IPAKAPEIIDVSSKAEEVKIMTITR-----KKEVQKEKEAVYEKKQ 9060 Query: 330 LVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQ 384 V ++K+V + +E + +V+P QP + + ++ V+ ++ HE+ Sbjct: 9061 AVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEE 9115 Score = 35.8 bits (81), Expect = 0.16 Identities = 59/291 (20%), Positives = 108/291 (37%), Gaps = 48/291 (16%) Query: 105 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 164 SP A P + P+ P ++ P+ + PPP VP P + Sbjct: 9394 SPPPAVPEI--PKKKVPEERKPVPRKEEEV---PPPPKVPALPKK--------------- 9433 Query: 165 SSTTPNRKDSSSQTMPVEDKSDPP----------EGSEEAAEPRMDTPEDQDLPPCPEDI 214 P ++ + +PV K+ PP E AE ++ Q + ++ Sbjct: 9434 ----PVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEV 9489 Query: 215 AKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDL 274 + E+ E E E + R EE E E + +V +P+ V ++ Sbjct: 9490 SAEEEWSYSEEE--EGVSISVYREEEREEEEEAEVT-EYEVMEEPE-EYVVEEKLHIISK 9545 Query: 275 LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 334 EA A+V R + +++ +P+IP+ + P +A + PE V Sbjct: 9546 RVEAEPAEVTERQEKKIV---------LKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAP 9596 Query: 335 KQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHP-PAQVSVQPPEQTHEQ 384 + ++ P++ +P + P V E P PA+V+ + + T E+ Sbjct: 9597 VPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEE 9647 Score = 34.7 bits (78), Expect = 0.37 Identities = 56/302 (18%), Positives = 108/302 (35%), Gaps = 51/302 (16%) Query: 113 LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP---QKQARTSSSTTP 169 + P + P ++ P A + PPP VP P + + P + +A P Sbjct: 10810 IAPEEEIAPEEEKPVPVAEEEEPEVPPPA-VPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868 Query: 170 NRKDSSSQTMPVEDKSDPPEGSEEAAE--------PRMDTPEDQDLPPCPE--------- 212 + + P P E+ E P+ PE +P E Sbjct: 10869 EKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGG 10928 Query: 213 DIAKEKRTPAPEPEPCEASELPA---------------KRLRSSEEPTEKEPPG-----Q 252 + K P +PEP E L + K+L ++P EPP + Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEE 10988 Query: 253 LQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQ 312 ++V + +P+ T+ P++ P A LP +P+ + +A+V++ P + T Sbjct: 10989 VEVPTVTKRERKIPEPTKVPEIKP----AIPLPAPEPKP-KPEAEVKTIKPPPVEPEPTP 11043 Query: 313 VQ-----PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQE 367 + P + K+A+ + E + ++ ++ P + + ++ + P E Sbjct: 11044 IAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDE 11103 Query: 368 HP 369 P Sbjct: 11104 AP 11105 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 63.2 bits (152), Expect = 1e-09 Identities = 90/360 (25%), Positives = 113/360 (31%), Gaps = 69/360 (19%) Query: 106 PGLAAPSLT-PPQLATPNLQQFFPQATRQSLLGP----PPVGVPMNPSQFNLSGRNPQKQ 160 P A PS+T PP A P+LQ P SL P PP + ++ Q S +P Q Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424 Query: 161 ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRT 220 A S T R+ +S T P S PP+ P + P LP P Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPD------SPPLQAP--LSLPASPPLQTSLSPA 476 Query: 221 PAPEPEPCEASELPAKRLRSSEEPTEK-----EPPGQLQVK------AQPQARMTVPKQT 269 +P P L A +S P PP + Q P A +T P Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536 Query: 270 QTPDLLPEALEAQVLPRFQPRV----------LQVQAQVQSQTQPRIPST---------D 310 P L P L+ P P + LQ + P PS+ Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP 596 Query: 311 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL---QQEAEPQKQVQPQVHTQAQPSVQ--- 364 P LQ SP L Q P L +A P P + A PS Q Sbjct: 597 ALASPPLQGLPSPPLSP--LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654 Query: 365 ------------PQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 412 P PP Q PP P P P Q P + L++PP Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP------PSQAPPSLAAPPLQVPP 708 Score = 57.0 bits (136), Expect = 7e-08 Identities = 84/324 (25%), Positives = 110/324 (33%), Gaps = 52/324 (16%) Query: 108 LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSST 167 L++P P A +L PQA SL+ PP +Q +L+ P Q +S T Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL------ETQSSLAP--PSLQTPPASLT 531 Query: 168 TPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCP-----EDIAKEKRTPA 222 TP ++ S P + P + P P PP P + TP Sbjct: 532 TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP 591 Query: 223 PEPEPCEASE----LPAKRLRSSEEPTEKEPPG----QLQVKAQPQARMTV-PKQTQTPD 273 P+ P AS LP+ L P + PP LQ P A + P T +P Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651 Query: 274 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 333 P AL +L P P VQ A SP Sbjct: 652 A-PNALAVHLLQA-----------------PFSPPPSPPVQAPFSPPASPPVSPS--ATP 691 Query: 334 QKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVS---VQPPEQTHEQPHTQPQ 390 Q P L A P QV P A P + P PP Q PP Q P P Sbjct: 692 PSQAPPSL---AAPPLQVPPS--PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP 746 Query: 391 VSLLA--PEQTPVVVHVCGLEMPP 412 +S A P + P ++ L++PP Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPP 770 Score = 47.4 bits (111), Expect = 5e-05 Identities = 97/437 (22%), Positives = 155/437 (35%), Gaps = 60/437 (13%) Query: 96 GNLRGYGMASP---GLAAPSLTPPQLATPNLQQFFPQATRQSL---LGPPPVGVPMNPSQ 149 G L +A+P G A + PP A L P + + L PP P + Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356 Query: 150 FNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPP 209 P QA S +T P + S QT+P P + P + PP Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIP------PIQVPHSLTSPSLQA------PP 404 Query: 210 CPEDIAKEKRTPAPEPEPCEASE-----LPAKRLRSSEEPTE--KEPPGQLQVKAQPQAR 262 P ++ + T + +A+ P + S P+ PP ++A Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464 Query: 263 MTVPKQTQ-TPDLLPEALEAQVLPRFQPRVL---QVQAQVQSQTQPRIPSTDTQVQPKLQ 318 + P QT +P + P + + P L QA + S P + + + P LQ Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524 Query: 319 KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPP 378 + T+P L P LQ + P P + T P+ P + PP+ ++ PP Sbjct: 525 TPPASLTTPP-LENLPSLAPPPLQTASAP--LTTPHLETPPCPAPCPLQAPPSPLTTPPP 581 Query: 379 EQTHEQPHTQPQVSLLAPEQTPVVVH--VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSME 436 E T ++ P+ P + + GL PP + A T P +++ Sbjct: 582 E-------TPSSIATPPPQAPPALASPPLQGLPSPPLSPLA------TPPPQAPPXLALP 628 Query: 437 EIQNESA--CGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSD 494 +Q + + + + P +L V +LQ+ FS P PV P Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAP------NALAVHLLQA----PFSPPPSPPVQAPFS 678 Query: 495 SVSSTPAATS-TPSKQA 510 +S P + S TP QA Sbjct: 679 PPASPPVSPSATPPSQA 695 Score = 42.0 bits (97), Expect = 0.002 Identities = 74/307 (24%), Positives = 103/307 (33%), Gaps = 45/307 (14%) Query: 138 PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP 197 P PV P S G QK R S+ T R ++ + P+ S +A Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT----------EAPKRSALSAGA 160 Query: 198 RMDTPEDQDLPPCPEDIAKEKRT---------PAPEPEPCEASELPAKRLRSSEE--PTE 246 R DT P P +A+ R PAP P +E P K + S+ E TE Sbjct: 161 RRDTSGPTPGTPSPA-MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219 Query: 247 KEPPGQLQVKA-----QPQARMTVPKQTQTPDLLPEALEAQVLPR-----FQPRVLQVQA 296 P + + A +P +R T A+ PR QP+ +QA Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279 Query: 297 QVQSQ-TQPR---------IPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 346 Q T PR + S+ +A+ P++ P A Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLAT 339 Query: 347 PQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ-PPEQTHEQPHTQPQVSLLAPEQTPVVVHV 405 P P A PS+Q PPA Q PP T P + + P Q P + Sbjct: 340 PLPLAPPS--PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397 Query: 406 CGLEMPP 412 L+ PP Sbjct: 398 PSLQAPP 404 Score = 37.7 bits (86), Expect = 0.043 Identities = 54/208 (25%), Positives = 70/208 (33%), Gaps = 45/208 (21%) Query: 46 PPQAPLPMAVSR-GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMA 104 PPQAP P+A +PP P P ++ T + L A LQ M Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV---PPLLAAPPLQVPPSPPASLPM- 778 Query: 105 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 164 SP P PP LATP LQ L PP P + F+ S P S Sbjct: 779 SPLAKPPPQAPPALATPPLQ----------ALPSPPASFP-GQAPFSPSASLPM-----S 822 Query: 165 SSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPE 224 TP PP+ A P + P PP + +R P P Sbjct: 823 PLATP-----------------PPQAPPVLAAPLLQVPPS---PPASPTLQAPRRPPTPG 862 Query: 225 PEPCEASELPAKRLRSSEEPTEKEPPGQ 252 P+ + + RL + P PP + Sbjct: 863 PD----TSVSGPRLTLALAPGPPPPPSR 886 Score = 31.2 bits (69), Expect = 4.1 Identities = 80/297 (26%), Positives = 99/297 (33%), Gaps = 57/297 (19%) Query: 42 LQQSP-PQAPLPMAVSRGLPPQQP---QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGN 97 LQ P P A LPM+ PPQ P P L + AS + + L Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM---- 821 Query: 98 LRGYGMASPGLAAPSLTPPQLATPNLQ-QFFPQA--TRQSLLGPPPVGVPMNPS----QF 150 SP P PP LA P LQ P A T Q+ PP G + S Sbjct: 822 -------SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874 Query: 151 NLSGRNPQKQARTSSSTTPN---RKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDL 207 L+ P +R+ SST SSS T E+ G E A P D +L Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA--AASPPPDAEL 932 Query: 208 PPCPEDIAKEKRTPAP---------EPEPCEASELPAK-----RLRSSEEPTEKEP-PGQ 252 C A R PAP P P + P + +E P P PG Sbjct: 933 AACHP--AAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 990 Query: 253 LQVKAQP-------------QARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA 296 L P A PKQ + +L AL+A V+ R L + A Sbjct: 991 LDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA 1047 >gi|197276594 RNA binding motif protein 20 [Homo sapiens] Length = 1227 Score = 62.8 bits (151), Expect = 1e-09 Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%) Query: 615 KTPRKFVEHVKSQGH-KDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 673 + P FV+ K++G +D A E LE++ + E + C E E + Sbjct: 1057 RQPSPFVDDCKTRGTPEDGACEGSPLEEKASPPIETD---LQNQACQEVLTPENSRYVEM 1113 Query: 674 EEIEVEEELCKQVRSRD-ISREEWKGSETYSP-NTAYGVDFLVPVMGYICRICHKFYHSN 731 + +EV +V + +S W+ + +S + GV+F+VP G+ C++C FY S Sbjct: 1114 KSLEVRSPEYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSE 1173 Query: 732 SGAQLSHCKSLGHFENLQKY 751 A++SHC+S H+ NLQKY Sbjct: 1174 ETAKMSHCRSAVHYRNLQKY 1193 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 62.8 bits (151), Expect = 1e-09 Identities = 67/306 (21%), Positives = 117/306 (38%), Gaps = 45/306 (14%) Query: 184 KSDPPEGSE--EAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSS 241 +SD EG E EA E + P D + + PE E EA E + S Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPES 1887 Query: 242 EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 301 E+ E ++Q +++ K+ Q EALE + + Sbjct: 1888 EDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETE-----------------GE 1930 Query: 302 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQ--- 358 +P + Q + ++A+ QT PE V++ ++ + + Q E+E + ++ +V TQ Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAE 1990 Query: 359 --AQPSVQPQEHPPAQ----------------VSVQPPEQTHEQPHTQPQVSLLAPEQTP 400 AQP + E P A+ V QP + E + + + P Sbjct: 1991 GEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQP 2050 Query: 401 VVVHVCGLEMPPDAVEAGGGMEKTLPE--PVGTQVSMEEIQNES---ACGLDVGECENRA 455 V E +A EA G +++ E P V +E + E+ + G++ E E A Sbjct: 2051 ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEA 2110 Query: 456 REMPGV 461 ++ G+ Sbjct: 2111 QKAEGI 2116 Score = 53.9 bits (128), Expect = 6e-07 Identities = 60/247 (24%), Positives = 102/247 (41%), Gaps = 26/247 (10%) Query: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCPEDI- 214 P+ + + + + P D + PE EEA E + E + + P ED+ Sbjct: 2027 PKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVD 2086 Query: 215 AKEKRTPA-PEPEPCEASELP--AKRLRSSEEPTEKEPPGQLQVKAQPQAR-MTVPKQTQ 270 A+E A PE E EA E A++ E P + + +AQP++ + P+ Sbjct: 2087 AQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAP-------ETEGEAQPESEGIEAPEAEG 2139 Query: 271 TPDLLPEALEAQVLP-RFQPRVLQVQAQ-VQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 328 E +EAQ QP ++AQ + + QP + + +A+ + PE Sbjct: 2140 EAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAP-------EAEGEAQPE 2192 Query: 329 HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQ--THEQPH 386 ++ + + + Q E E + P+ +AQP + E P A+ QP + T + Sbjct: 2193 SEGIEAPEAEGEAQPELEGVEA--PEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250 Query: 387 TQPQVSL 393 PQVSL Sbjct: 2251 GSPQVSL 2257 Score = 45.4 bits (106), Expect = 2e-04 Identities = 87/440 (19%), Positives = 159/440 (36%), Gaps = 65/440 (14%) Query: 158 QKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE--DQDLPPCPEDIA 215 + Q + TP ++ + P + ++ PE +EA +P ++ E + + PE Sbjct: 1882 EAQPESEDVETP---EAEWEVQPESEGAEAPEAEKEA-QPETESVEALETEGEDEPESEG 1937 Query: 216 KEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLL 275 E + + E P + S+E E+ P V+A + V Q + Sbjct: 1938 AEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEA---LEVEVETQEAEGEAQ 1994 Query: 276 PEALEAQVLPRFQPRVLQVQAQVQSQT-----QPRIPSTDTQVQPKLQKQAQTQTSPEHL 330 PE+ + + P + + + + + Q ++ QP+ + Q ++ + PE Sbjct: 1995 PESEDVEA-PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESD 2053 Query: 331 VLQQKQVQPQLQQEAEPQKQVQPQVHT------------QAQPSVQPQEHPPAQVSVQPP 378 ++ + + + Q+ ++ + + H +AQP + E P A+ Q Sbjct: 2054 GVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKA 2113 Query: 379 EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA--VEAGGGMEKTLPEPVG--TQVS 434 E E P T+ + PE + E P++ VEA + PE G Q + Sbjct: 2114 EGI-EAPETEGEAQ---PESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEA 2169 Query: 435 MEEIQNESACGLDVGECENRAR-EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPS 493 EE Q E G++ E E A+ E G+ ++ A + P Sbjct: 2170 EEEAQPELE-GVEAPEAEGEAQPESEGIEA----------PEAEGEAQPELEGVEAPEAE 2218 Query: 494 DSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQ-DHMSEPQHQQRLGEIQHMSQACL 552 + P TP + +A S+ E Q + PQ G+ + S+ Sbjct: 2219 EEAQPEPEGVETPEAEG--------EAQPESEGETQGEKKGSPQVSLGDGQSEEASE--- 2267 Query: 553 LSLLPVPRDVLETEDEEPPP 572 S PVP D PPP Sbjct: 2268 -SSSPVPED-----RPTPPP 2281 Score = 30.0 bits (66), Expect = 9.0 Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 14/89 (15%) Query: 621 VEHVKSQGHKD------KAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEE 674 VE ++++G + +A+E + +E GQ + +++ E +EE + + ED E Sbjct: 1922 VEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ---EAEEEAQPESEDVE 1978 Query: 675 EIEVEEELCK-----QVRSRDISREEWKG 698 +EVE E + Q S D+ E +G Sbjct: 1979 ALEVEVETQEAEGEAQPESEDVEAPEAEG 2007 >gi|58530845 zyxin [Homo sapiens] Length = 572 Score = 62.4 bits (150), Expect = 2e-09 Identities = 69/298 (23%), Positives = 109/298 (36%), Gaps = 26/298 (8%) Query: 108 LAAPSLTPPQLATPNLQQFF-PQATRQSLLGPPPVGVPMNPSQFN---LSGRNPQKQART 163 +AAP +P + + F+ PQ ++ P P P P G + R Sbjct: 1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 60 Query: 164 SSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 223 P +D P+ D EG+ A P P ++ PP P +E+ P+P Sbjct: 61 GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAP---LEEEIFPSP 117 Query: 224 EPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV 283 P P E P + +P EK L++ + + K + +A+V Sbjct: 118 PPPPEEEGG-PEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKN--------DPFKARV 168 Query: 284 LPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 343 + P + +S T+P + T P + + +Q P QV Q Sbjct: 169 SSGYVPPPVATPFSSKSSTKPA--AGGTAPLPPWKSPSSSQPLP--------QVPAPAQS 218 Query: 344 EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 401 + + Q QPQ Q Q VQ Q P + + QP P P+ S + P+ TPV Sbjct: 219 QTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPV 276 >gi|4508047 zyxin [Homo sapiens] Length = 572 Score = 62.4 bits (150), Expect = 2e-09 Identities = 69/298 (23%), Positives = 109/298 (36%), Gaps = 26/298 (8%) Query: 108 LAAPSLTPPQLATPNLQQFF-PQATRQSLLGPPPVGVPMNPSQFN---LSGRNPQKQART 163 +AAP +P + + F+ PQ ++ P P P P G + R Sbjct: 1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 60 Query: 164 SSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 223 P +D P+ D EG+ A P P ++ PP P +E+ P+P Sbjct: 61 GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAP---LEEEIFPSP 117 Query: 224 EPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV 283 P P E P + +P EK L++ + + K + +A+V Sbjct: 118 PPPPEEEGG-PEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKN--------DPFKARV 168 Query: 284 LPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 343 + P + +S T+P + T P + + +Q P QV Q Sbjct: 169 SSGYVPPPVATPFSSKSSTKPA--AGGTAPLPPWKSPSSSQPLP--------QVPAPAQS 218 Query: 344 EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 401 + + Q QPQ Q Q VQ Q P + + QP P P+ S + P+ TPV Sbjct: 219 QTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPV 276 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 62.0 bits (149), Expect = 2e-09 Identities = 103/421 (24%), Positives = 146/421 (34%), Gaps = 59/421 (14%) Query: 111 PSLTPPQ-LATPNLQQFFPQA-----TRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 164 P++TPP TP L P + T S GP P PS P R Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA--TPSHKGGPAMTPPSPKRGP 1393 Query: 165 SSTTPNRKDSSSQTMPVEDKSDP--PEGSEEAAEPRMDTPEDQDLPP---CPEDIAKEKR 219 + +P +S +P+ K P P E AA TP DL P P + K Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA-----TPSKGDLTPPAVTPVSLKKAPA 1448 Query: 220 TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL 279 T AP+ P S L + P+ KEPP QV A + PK+ P + Sbjct: 1449 TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV-----ATSSSPKKAPA---TPAPM 1500 Query: 280 EAQVLPRFQP-RVLQVQAQVQSQTQPRIPS-------TDTQVQPK--LQKQAQTQTSPEH 329 A LP P +V A S+ P P+ T + PK L A T SP+ Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560 Query: 330 ---LVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 386 + ++ +EA V P + A PS + PPA S P E Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA-PSPKELLIPPAVTSPSPKEAP----- 1614 Query: 387 TQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGL 446 T P V+ +PE+ P G P + T P V ++ Q Sbjct: 1615 TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ------- 1667 Query: 447 DVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTP 506 ++ +P G +V + + +S T P P+ S +++P P Sbjct: 1668 -------ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP 1720 Query: 507 S 507 S Sbjct: 1721 S 1721 Score = 47.0 bits (110), Expect = 7e-05 Identities = 87/388 (22%), Positives = 136/388 (35%), Gaps = 42/388 (10%) Query: 33 QQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTN---SASLLNGSMLQRAL 89 ++LL + SP +AP P AV+ P + P P T+ + S L S A Sbjct: 1597 KELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656 Query: 90 LLQQLQGNLRGYGMASPGLAAPS------LTPPQLATPNLQ---QFFPQATRQSLLGPPP 140 + ++ + P P+ + P +TP + + PQ + S PP Sbjct: 1657 VTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP- 1715 Query: 141 VGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMD 200 + +PS N G + P +KDSS +T +D S P+G E + Sbjct: 1716 --ICPDPSAKN--GSKGPLSTVAPAPLLPVQKDSS-KTAKGKDASHSPKGPLAPPESKAS 1770 Query: 201 TPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQ 260 TP A EK P PE A+ P L + P PP Q + + P Sbjct: 1771 TPLTA--------AAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPG 1822 Query: 261 ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS--QTQPRIPSTDTQVQPKLQ 318 + P + P A E ++LP P + QS P S V Sbjct: 1823 LVLESPSKPLAP-----ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSA 1877 Query: 319 KQAQTQTSP-EHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP 377 KQ T+ + + P+L+++ Q Q Q + + E P V Sbjct: 1878 KQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQ---QAQLAAAAEIDEEP-----VSK 1929 Query: 378 PEQTHEQPHTQPQVSLLAPEQTPVVVHV 405 +Q+ + + +S L Q V V Sbjct: 1930 AKQSRSEKKARKAMSKLGLRQVTGVTRV 1957 Score = 43.1 bits (100), Expect = 0.001 Identities = 53/236 (22%), Positives = 73/236 (30%), Gaps = 24/236 (10%) Query: 45 SPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRG---Y 101 SP PLP P P L + +G + L G+ A +G Sbjct: 1046 SPAATPLPKGA-----PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100 Query: 102 GMASPGLAAPS------LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR 155 G P A P TPP P P + + L PPP G P P+ S + Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160 Query: 156 N-----PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPC 210 P K A T+ + TP T + P + + + + TP + P Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220 Query: 211 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP 266 P + P P A PA + P+ K P K P P Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPA-----ATPPSPKGGPATPPPKGAPTPPAATP 1271 Score = 42.4 bits (98), Expect = 0.002 Identities = 92/440 (20%), Positives = 143/440 (32%), Gaps = 39/440 (8%) Query: 102 GMASP----GLAAPSLTPPQ----LATPNLQ------QFFPQATRQSLLGPPPVGVPMNP 147 G+A+P P+ TPP LATP+ + P + + L P P G P P Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221 Query: 148 SQFNLSGRN-----PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTP 202 + S + K A T+ + TP T P + PP + + + + TP Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281 Query: 203 EDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP-QA 261 + P P + P+P+ P + A ++ P+ K PG K P Sbjct: 1282 PHKGAPN-PAVVT----PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336 Query: 262 RMTVPKQTQTPDL---LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ 318 +T P TP L P + P + A + P + + P + Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396 Query: 319 KQAQTQTSPEHLVLQQKQVQP---QLQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVS 374 TSP + L K+ + A P K + P T P P Sbjct: 1397 SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP---K 1453 Query: 375 VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGM-EKTLPEPVGTQV 433 P + + T P V+ +P++ P V P A M TLP + + Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513 Query: 434 SMEEIQNESACGLDVGECENRAREMPGVWGAGGSL---KVTILQSSDSRAFSTVPLTPVP 490 S +++ P +L +T+ + A T P Sbjct: 1514 KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT 1573 Query: 491 RPSDSVSSTPAATSTPSKQA 510 S SS PA T + K A Sbjct: 1574 PSSKEASSPPAVTPSTYKGA 1593 Score = 34.3 bits (77), Expect = 0.48 Identities = 73/334 (21%), Positives = 100/334 (29%), Gaps = 67/334 (20%) Query: 138 PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPP-----EGSE 192 P P+GV ++P + R P K+ T + SS PVE P +GS+ Sbjct: 794 PSPLGVSVSPQ----TKRPPTKKGSAGPDTPIG--NLSSPVSPVEASFLPENSLSFQGSK 847 Query: 193 EA-AEPRMDTPEDQDLPPCPEDIAK---------EKRTPAPE----PEPCEASELPAKR- 237 ++ A TP P P + K TP P P P E PA + Sbjct: 848 DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907 Query: 238 -----LRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 292 + SS + P + A P PK TP P A P+ P Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPS-----PKGAPTP---PAATPPS--PKGGP--- 954 Query: 293 QVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQ---QEAEPQK 349 + P+ T P K SP+ P + P+ Sbjct: 955 -------ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007 Query: 350 QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH-------------TQPQVSLLAP 396 P T P P P + + PP T P T P +L +P Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067 Query: 397 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVG 430 + P + G PP A P P G Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101 Score = 32.0 bits (71), Expect = 2.4 Identities = 77/368 (20%), Positives = 109/368 (29%), Gaps = 60/368 (16%) Query: 45 SPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMA 104 SP AP P AV+ P P+ L + T + S++N Sbjct: 860 SPKGAPTPSAVT----PLSPKGVTLPPKETPTPSVVN-------------------LPFP 896 Query: 105 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 164 G A P+ P Q ++ P+ R + P P G+P +PS K A T Sbjct: 897 KEGPATPA--PKQAPALSMTSSSPKKARAT---PAPKGIPASPSP---------KGAPTP 942 Query: 165 SSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPE 224 + TP T + PP + + + TP + P P + Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT 1002 Query: 225 PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL 284 P P A PA T P G P+ T P TP + A L Sbjct: 1003 PSPKGAPTPPA--------VTPPSPKGSPAATPFPKGASTPP--AATPPSPKGSPAATPL 1052 Query: 285 PRFQPRVLQVQAQVQSQTQPRIPS-----TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 339 P+ P + P PS T P K SP+ + P Sbjct: 1053 PKGAP-TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111 Query: 340 QLQQE-AEPQKQVQPQVHTQAQPS------VQPQEHPPAQVSVQPPEQTHEQPHTQPQVS 392 + A P + P PS P + P + PP P+ + Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA 1171 Query: 393 LLAPEQTP 400 P TP Sbjct: 1172 PTTPAATP 1179 Score = 31.2 bits (69), Expect = 4.1 Identities = 61/286 (21%), Positives = 86/286 (30%), Gaps = 27/286 (9%) Query: 143 VPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSS--SQTMPVEDKSD--PPEGSEEAAEPR 198 +P N F S +P A T S T P+ K + S P+ K PP+ + + Sbjct: 836 LPENSLSFQGSKDSP---ATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN 892 Query: 199 MDTPEDQDLPPCPEDIA----------KEKRTPAPEPEPCEASELPAKRLRSSEEPTEKE 248 + P++ P P+ K + TPAP+ P S A ++ P+ K Sbjct: 893 LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952 Query: 249 PPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS 308 P K P P + P A P P + S P Sbjct: 953 GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012 Query: 309 TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEH 368 T PK A P+ A P + P PS P+ Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS--PKGG 1070 Query: 369 PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA 414 P P T P + +P+ P G MPP A Sbjct: 1071 PATPSLKGAP--------TPPAATPPSPKGGPATPSPKGAPMPPAA 1108 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.127 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,470,244 Number of Sequences: 37866 Number of extensions: 2365462 Number of successful extensions: 45779 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 535 Number of HSP's successfully gapped in prelim test: 1081 Number of HSP's that attempted gapping in prelim test: 19657 Number of HSP's gapped (non-prelim): 13368 length of query: 818 length of database: 18,247,518 effective HSP length: 111 effective length of query: 707 effective length of database: 14,044,392 effective search space: 9929385144 effective search space used: 9929385144 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.