BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 [Homo sapiens] (837 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ... 1698 0.0 gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ... 1692 0.0 gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ... 1662 0.0 gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [... 1662 0.0 gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ... 1630 0.0 gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 88 3e-17 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 83 9e-16 gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 78 4e-14 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 77 9e-14 gi|56549696 E1A binding protein p400 [Homo sapiens] 71 4e-12 gi|38788274 bromodomain PHD finger transcription factor isoform ... 69 2e-11 gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens] 67 7e-11 gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 66 1e-10 gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 66 1e-10 gi|38788260 bromodomain PHD finger transcription factor isoform ... 66 2e-10 gi|17017963 forkhead box P2 isoform I [Homo sapiens] 65 2e-10 gi|22538413 forkhead box P2 isoform III [Homo sapiens] 65 2e-10 gi|149999352 forkhead box P2 isoform II [Homo sapiens] 65 2e-10 gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 64 4e-10 gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 64 6e-10 gi|110349719 titin isoform N2-A [Homo sapiens] 64 8e-10 gi|148277037 AP2 associated kinase 1 [Homo sapiens] 63 1e-09 gi|197276594 RNA binding motif protein 20 [Homo sapiens] 63 1e-09 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 63 1e-09 gi|221139761 zinc finger protein 853 [Homo sapiens] 62 2e-09 gi|33286444 mastermind-like 2 [Homo sapiens] 62 3e-09 gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 62 3e-09 gi|4507379 TATA box binding protein [Homo sapiens] 60 6e-09 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 6e-09 gi|110347429 mediator complex subunit 12 [Homo sapiens] 60 6e-09 >gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 [Homo sapiens] Length = 837 Score = 1698 bits (4398), Expect = 0.0 Identities = 837/837 (100%), Positives = 837/837 (100%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP Sbjct: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240 Query: 241 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 300 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA Sbjct: 241 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 300 Query: 301 QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL 360 QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL Sbjct: 301 QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL 360 Query: 361 QQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 420 QQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV Sbjct: 361 QQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 420 Query: 421 VVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGV 480 VVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGV Sbjct: 421 VVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGV 480 Query: 481 WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS 540 WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS Sbjct: 481 WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS 540 Query: 541 CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQL 600 CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQL Sbjct: 541 CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQL 600 Query: 601 YYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEK 660 YYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEK Sbjct: 601 YYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEK 660 Query: 661 EIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSET 720 EIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSET Sbjct: 661 EIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSET 720 Query: 721 YSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTT 780 YSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTT Sbjct: 721 YSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTT 780 Query: 781 RPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 837 RPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT Sbjct: 781 RPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 837 >gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 [Homo sapiens] Length = 842 Score = 1692 bits (4382), Expect = 0.0 Identities = 837/842 (99%), Positives = 837/842 (99%), Gaps = 5/842 (0%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 Query: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235 PQKQARTSSSTTPNRK TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240 Query: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300 Query: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360 Query: 356 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 415 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP Sbjct: 361 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 420 Query: 416 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 475 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR Sbjct: 421 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 480 Query: 476 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 535 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY Sbjct: 481 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 540 Query: 536 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 595 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC Sbjct: 541 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 600 Query: 596 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 655 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL Sbjct: 601 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 660 Query: 656 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 715 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW Sbjct: 661 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 720 Query: 716 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 775 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN Sbjct: 721 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 780 Query: 776 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 835 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL Sbjct: 781 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 840 Query: 836 KT 837 KT Sbjct: 841 KT 842 >gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo sapiens] Length = 898 Score = 1662 bits (4304), Expect = 0.0 Identities = 837/898 (93%), Positives = 837/898 (93%), Gaps = 61/898 (6%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 Query: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235 PQKQARTSSSTTPNRK TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240 Query: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300 Query: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360 Query: 356 VQPQLQQEAEPQ------------------------------------------------ 367 VQPQLQQEAEPQ Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420 Query: 368 ----KQVQ----PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 419 KQVQ PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480 Query: 420 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 479 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540 Query: 480 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 539 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600 Query: 540 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 599 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660 Query: 600 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 659 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720 Query: 660 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 719 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780 Query: 720 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 779 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840 Query: 780 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 837 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898 >gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo sapiens] Length = 898 Score = 1662 bits (4304), Expect = 0.0 Identities = 837/898 (93%), Positives = 837/898 (93%), Gaps = 61/898 (6%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 Query: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235 PQKQARTSSSTTPNRK TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240 Query: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300 Query: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360 Query: 356 VQPQLQQEAEPQ------------------------------------------------ 367 VQPQLQQEAEPQ Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420 Query: 368 ----KQVQ----PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 419 KQVQ PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480 Query: 420 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 479 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540 Query: 480 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 539 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600 Query: 540 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 599 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660 Query: 600 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 659 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720 Query: 660 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 719 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780 Query: 720 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 779 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840 Query: 780 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 837 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898 >gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 [Homo sapiens] Length = 818 Score = 1630 bits (4221), Expect = 0.0 Identities = 813/842 (96%), Positives = 813/842 (96%), Gaps = 29/842 (3%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96 Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN Sbjct: 97 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156 Query: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235 PQKQARTSSSTTPNRK TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK Sbjct: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216 Query: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP Sbjct: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276 Query: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ Sbjct: 277 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336 Query: 356 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 415 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP Sbjct: 337 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 396 Query: 416 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 475 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR Sbjct: 397 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 456 Query: 476 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 535 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY Sbjct: 457 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 516 Query: 536 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 595 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC Sbjct: 517 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 576 Query: 596 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 655 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL Sbjct: 577 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 636 Query: 656 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 715 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW Sbjct: 637 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 696 Query: 716 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 775 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN Sbjct: 697 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 756 Query: 776 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 835 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL Sbjct: 757 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 816 Query: 836 KT 837 KT Sbjct: 817 KT 818 >gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] Length = 788 Score = 88.2 bits (217), Expect = 3e-17 Identities = 88/319 (27%), Positives = 129/319 (40%), Gaps = 46/319 (14%) Query: 5 QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54 Q QQQ+QQQQQQLQ++ QQQQ QQQQ QQQQ LQ Q +QQ P PQ P A Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285 Query: 55 VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAM 102 + + L PP QPQQP + N S L + L+ Q L G + Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342 Query: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL--- 159 PP + A + + + + A + Q+ P +Q + + Sbjct: 343 PPLKFVRAPMVVQQPPVQP----QVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIR 398 Query: 160 -LGPPPVGVPMNPSQFNLSGRNPQKQARTS-----SSTTPNRKTMPVEDKSDPPEGSEEA 213 PP V PS GR P Q S SS +P ++ + PP+ S + Sbjct: 399 ARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQP 458 Query: 214 AEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQ 273 +P + P P + P+P P+P + S + A+ ++ P+ PG L Sbjct: 459 GQPSSQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS----PGPLN 510 Query: 274 VKAQPQARMTVPKQTQTPD 292 P + M+ +Q + Sbjct: 511 TPVNPSSVMSPAGSSQAEE 529 Score = 63.9 bits (154), Expect = 6e-10 Identities = 57/195 (29%), Positives = 90/195 (46%), Gaps = 11/195 (5%) Query: 241 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 300 AP ++ P +L+ + +++ Q Q + Q QA + +Q Q +A ++ Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194 Query: 301 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 359 + +FQ V Q Q Q Q Q Q + Q Q ++Q+Q Q L LQQ+Q Q Q Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254 Query: 360 LQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 418 QQ+ + Q Q QP + QP +Q + PP+Q Q +Q H H QP P+Q Sbjct: 255 QQQQQQQQALQAQPPIQ---QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQP 308 Query: 419 PVVVHVCGLEMPPDA 433 PV + ++PP + Sbjct: 309 PVAQNQPS-QLPPQS 322 Score = 53.9 bits (128), Expect = 6e-07 Identities = 67/267 (25%), Positives = 99/267 (37%), Gaps = 25/267 (9%) Query: 152 PQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSE 211 P QSL G P G + + R P + S P+ PP G+ Sbjct: 81 PMNALQSLTGGPAAGA----AGIGMPPRGPGQSLGGMGSL--GAMGQPMSLSGQPPPGTS 134 Query: 212 EAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQ 271 A M P+ + ++ + + + + + ++ +++ Q Sbjct: 135 GMAPHSMAVVSTAT----PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQ 190 Query: 272 LQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQ 331 Q A Q V +Q Q L + + Q L + Q Q Q+Q Q Q Q Sbjct: 191 AQQSAMQQQFQAVVQQQQ--QLQQQQQQQQHLIKLHH---QNQQQIQQQQQQLQRIAQLQ 245 Query: 332 VQPKLQKQAQTQTSPEHLVLQQKQVQ-PQLQQEAEPQKQVQPQV-----HTQ-AQPSVQP 384 +Q + Q+Q Q Q + + Q +Q P +QQ P Q PQ HTQ QP QP Sbjct: 246 LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQP 305 Query: 385 QEHPPAQVSVQPPEQTHEQPHTQPQVS 411 Q+ P AQ P Q Q TQP VS Sbjct: 306 QQPPVAQ---NQPSQLPPQSQTQPLVS 329 Score = 42.4 bits (98), Expect = 0.002 Identities = 55/205 (26%), Positives = 78/205 (38%), Gaps = 27/205 (13%) Query: 271 QLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ-PRVLQVQAQVQSQTQPRIPSTD 329 QLQ + Q Q + + + + Q + + Q + Q Q Q Q Q Q + + Sbjct: 209 QLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP 268 Query: 330 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQV----------HTQAQ 379 QP +Q Q Q P + QQ Q Q P + QP V +Q Q Sbjct: 269 PIQQPPMQ---QPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325 Query: 380 PSV-QPQEHPPAQVSVQPP----------EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLE 428 P V Q Q P + QPP +Q QP Q Q + + Q +V G++ Sbjct: 326 PLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV-APGVQ 384 Query: 429 MPPDAVEAGGGMEKTLPEPVGTQVS 453 M +A+ A GGM P T VS Sbjct: 385 MITEAL-AQGGMHIRARFPPTTAVS 408 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 83.2 bits (204), Expect = 9e-16 Identities = 143/495 (28%), Positives = 180/495 (36%), Gaps = 99/495 (20%) Query: 4 QQQQQQLQQQQQQLQQLQQQQL-QQQQLQQQQL--LQLQQLLQQSPPQAPLPMAVSRGLP 60 Q QQQQ QQQQQLQQ QQQQL QQQQLQQQQL Q QQ LQQ Q Sbjct: 3899 QLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQ 3958 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPAT-------YDTAGLT 113 QQ QQ Q LLN S R LL Q Q Q A+ P + + G Sbjct: 3959 QQQQQQQFQQQQQQQQMGLLNQS---RTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGAL 4015 Query: 114 MPTATL----GNLRGYGMASPGLAAPS----------LTPPQLAT------PNLQ----- 148 PT L N ++S PS TP +AT P+L Sbjct: 4016 GPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQL 4075 Query: 149 ---QFFPQATRQSLLGPPPVGVPMNPSQ----FNLSGRNPQKQ----ARTSSSTTPNRKT 197 Q PQ SL PP+ +P Q + +G Q + + +S+ P+ Sbjct: 4076 LLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA 4135 Query: 198 MPVEDKSDPPEGSEE----AAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELP 253 P D P + +P ++ P + P P P P P LP Sbjct: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQP---------PKPGPVLQSGQGLP 4186 Query: 254 AKRLRSSEEPTEKEPPGQLQ--VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 311 + PT + QLQ + PQ R P+Q Q Q+ R L Sbjct: 4187 GVGIM----PTVGQLRAQLQGVLAKNPQLRHLSPQQQQ-----------QLQALLMQRQL 4231 Query: 312 QVQAQVQSQTQP-RIPSTDTQ-------VQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE 363 Q Q+Q QT P + P T T QP+L QT P LQ+ P+ Q Sbjct: 4232 Q-QSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGP----LQELGAGPRPQ-- 4284 Query: 364 AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLA--PEQTPVV 421 P + P P + P P S Q P++ + P Q+ A P P Sbjct: 4285 -GPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT 4343 Query: 422 VHVCG--LEMPPDAV 434 G LE PP V Sbjct: 4344 PKPQGPTLEPPPGRV 4358 Score = 71.6 bits (174), Expect = 3e-12 Identities = 107/444 (24%), Positives = 161/444 (36%), Gaps = 64/444 (14%) Query: 4 QQQQQQLQQQQQQ----LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAP-----LPMA 54 Q+Q Q+++QQ++ + + + +Q QQQQ QQQQ Q +L SP Q+P LP Sbjct: 3575 QKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQ 3634 Query: 55 VSRGLPPQQPQQP--------LLNLQGTNSASLLNGSMLQRALLLQQLQ----GLDQFAM 102 + G Q PQ P L G G L AL QQ Q G A Sbjct: 3635 LLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAG 3694 Query: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQ----LATPNLQQFFPQATRQS 158 P + L LR G S L L Q LA QQ Q +Q Sbjct: 3695 PSGGFFPGNLA--------LRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQH 3746 Query: 159 LLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRM 218 LLG + Q+Q + N+ P PP + ++ Sbjct: 3747 LLGQVAI----------------QQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQL 3790 Query: 219 DTPEDQD----LPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV 274 Q L P + +++ A P+ P +++ ++ P Q Sbjct: 3791 SPQPPQGPQGMLGPAQVAVLQQQHPGALGPQG------PHRQVLMTQSRVLSSPQLAQQG 3844 Query: 275 KAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 334 + R+ +Q Q + L Q ++ Q + QP Q Q Sbjct: 3845 QGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQ 3904 Query: 335 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSV 394 +LQ+Q Q Q + + QQ+Q+Q Q Q+ + Q+Q+Q Q Q Q Q+ Q Sbjct: 3905 QLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ-----QQQQQLQQQQ 3959 Query: 395 QPPEQTHEQPHTQPQVSLLAPEQT 418 Q +Q +Q Q Q+ LL +T Sbjct: 3960 QQQQQQFQQQQQQQQMGLLNQSRT 3983 Score = 65.1 bits (157), Expect = 3e-10 Identities = 85/299 (28%), Positives = 118/299 (39%), Gaps = 40/299 (13%) Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 189 P L+PP +P P+A+R L PPP PM+P P + +R S Sbjct: 601 PPFEESPLSPPPEESPLSPP--PEASR---LSPPPEDSPMSPPPEESPMSPPPEVSRLSP 655 Query: 190 STTPNRKTMPVEDK--SDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 247 +R + P E+ S PPE S P PE L P PED +P PE Sbjct: 656 LPVVSRLSPPPEESPLSPPPEES-----PTSPPPEASRLSPPPED-----SPTSPPPEDS 705 Query: 248 EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ 307 AS P L S P E+ P L + +PQ + +++ P L P E + PR + Sbjct: 706 PASPPPEDSLMSL--PLEESP--LLPLPEEPQ----LCPRSEGPHLSPRPEEPHLSPRPE 757 Query: 308 PRVLQVQA-QVQSQTQPRIPS-TDTQVQPKLQKQAQ---TQTSPEHLVLQQKQVQPQLQQ 362 L QA + QP P +P L QA+ PE L L + +P L Sbjct: 758 EPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP 817 Query: 363 -EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP-PEQTHEQPHTQPQVSLLAPEQTP 419 EP QP+ + + PQ P + P PE++H P + PE+ P Sbjct: 818 VPEEPCLSPQPE-----ESHLSPQSEEPC---LSPRPEESHLSPELEKPPLSPRPEKPP 868 Score = 47.8 bits (112), Expect = 4e-05 Identities = 95/428 (22%), Positives = 160/428 (37%), Gaps = 68/428 (15%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63 + ++++LQ++QQ QLQ Q QQQQ QQ LL P QA Sbjct: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLS-----APGPAQA-------------- 3294 Query: 64 PQQPLLNLQGTNSASLLNGSMLQRALLL--QQLQGLDQFAMP--PATYDTAGLTMPTATL 119 ++L S+ L GS Q +L L + GL Q MP P + P+ + Sbjct: 3295 -----MSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAM 3349 Query: 120 GNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR 179 + +G+ ++ L P Q + P L Q +G P + M P Q + Sbjct: 3350 VSNQGHMLSGQHGGQAGLVPQQSSQPVLS--------QKPMGTMPPSMCMKPQQLAM--- 3398 Query: 180 NPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCP------ED 232 Q+Q S + ED DP ++ A + Q + P Sbjct: 3399 --QQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVS 3456 Query: 233 IAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPD 292 + ++ + P + + + RS+ +P++ P Q + Q Q + Sbjct: 3457 LLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRP----NPPTFAQGVINEADQRQYEE 3512 Query: 293 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVL- 351 L Q L + Q +VL+ Q V +++ + + + ++ + LV Sbjct: 3513 WL---FHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTE 3569 Query: 352 QQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVS 411 QQ ++Q QL Q + QK+ HT E+ Q Q +Q +Q H+ V Sbjct: 3570 QQSKIQKQLDQVRKQQKE-----HTNLM-----AEYRNKQQQQQQQQQQQQQQHS--AVL 3617 Query: 412 LLAPEQTP 419 L+P Q+P Sbjct: 3618 ALSPSQSP 3625 Score = 47.4 bits (111), Expect = 6e-05 Identities = 72/299 (24%), Positives = 112/299 (37%), Gaps = 35/299 (11%) Query: 137 LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS-----SST 191 L+PP +P P+A+R L PPP +P +P L P +++ S S Sbjct: 449 LSPPPEESPTSPP--PEASR---LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503 Query: 192 TPNRKTMPV----EDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 247 +P ++ P E PPE E P ++TP P E+ +P PE Sbjct: 504 SPPPESSPFSPLEESPLSPPE--ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561 Query: 248 EASELP-AKRLR-SSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPR 305 S P A RL EE PP + + P+A P ++P L P E+ + P Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP-LSPPPEESPLSP- 619 Query: 306 FQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 365 S+ P P D+ + P +++ PE L V +L E Sbjct: 620 ---------PPEASRLSP--PPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPE 667 Query: 366 PQKQVQPQVHTQAQPSVQPQE-HPPAQVS--VQPPEQTHEQPHTQPQVSLLAPEQTPVV 421 P + P + PP + S PPE + P + + L E++P++ Sbjct: 668 ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726 Score = 45.8 bits (107), Expect = 2e-04 Identities = 124/502 (24%), Positives = 163/502 (32%), Gaps = 90/502 (17%) Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPL---PMAVSRGL 59 +QQ Q + + QQ QQQQ QQQ L LQQ L Q L PM + L Sbjct: 3841 AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQL 3900 Query: 60 PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAMPPATYDTAGLTMPTA 117 QQ Q LQ L LQ+ L QQ Q L Q L Sbjct: 3901 QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ 3960 Query: 118 TLGN--LRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFN 175 + GL S T L +P QQ +Q LGP G+P P Q Sbjct: 3961 QQQQQFQQQQQQQQMGLLNQSRT---LLSPQQQQ-----QQQVALGP---GMPAKPLQHF 4009 Query: 176 LSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235 S P T T + T+ DP SE P + PE +A Sbjct: 4010 SS---PGALGPTLLLTGKEQNTV------DPAVSSEATEGPSTHQGGPLAIGTTPESMAT 4060 Query: 236 EKR---------------TPAPEPEPCEASELPAKRLRSSEEPTEK-------EPPGQLQ 273 E P P+P+P P RL ++ GQL Sbjct: 4061 EPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLG 4120 Query: 274 VKAQPQARMTVPKQTQTPDL----LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS-- 327 + +A +VP P + P ++ +L QP ++ +Q+ T P+ P Sbjct: 4121 SGSSSEA-SSVPHLLAQPSVSLGDQPGSMTQNLLGPQQP---MLERPMQNNTGPQPPKPG 4176 Query: 328 ----------------TDTQVQPKLQKQAQTQTSPEHL-VLQQKQVQPQLQQEAEPQKQV 370 T Q++ +LQ HL QQ+Q+Q L Q Q Q Sbjct: 4177 PVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQA 4236 Query: 371 QPQVHTQAQPSVQPQEHPPAQ--VSVQPPEQTHEQPHTQPQVSLLA---PEQTPVVVHVC 425 Q +P Q P Q + QP P T P L A P+ P Sbjct: 4237 VRQTPPYQEPGTQTS---PLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPP------ 4287 Query: 426 GLEMPPDAVEAGGGMEKTLPEP 447 L PP A+ G + P P Sbjct: 4288 RLPAPPGALSTGPVLGPVHPTP 4309 Score = 42.7 bits (99), Expect = 0.001 Identities = 76/363 (20%), Positives = 116/363 (31%), Gaps = 70/363 (19%) Query: 103 PPATYDTAGLTMPTATLG---NLRGY---------GMASPG---LAAPSLTPPQLATPN- 146 PPA T + PT G + G+ G SPG L P P Q+ + + Sbjct: 2117 PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDP 2176 Query: 147 --------LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPN---- 194 L+ FP A P P G P P S R Q +T P Sbjct: 2177 FGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRH 2236 Query: 195 ---------RKTMPVEDKSDPPE----GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPA 241 + P D PE G +A+EP + P + E +E + Sbjct: 2237 QPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASS 2296 Query: 242 PE---------PEPCEASELPAKRLRSSE----------EPTEKEPPGQ-LQVKAQPQAR 281 P P + L L++ + E + PG L+ + P A+ Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQ 2356 Query: 282 MTVPKQTQTPDLLPEA------LEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 335 P PD+ + + PR QP + + ++ P P + P+ Sbjct: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQ 2416 Query: 336 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ 395 Q +Q+ +P L + P + P +P Q++ P PP Q Sbjct: 2417 SQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP---Q 2473 Query: 396 PPE 398 PPE Sbjct: 2474 PPE 2476 Score = 37.7 bits (86), Expect = 0.045 Identities = 78/375 (20%), Positives = 122/375 (32%), Gaps = 56/375 (14%) Query: 129 SPGLAAPSLTP----PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFN--LSGRNPQ 182 SP P L+P P L+ + + + L P P ++P LS R P+ Sbjct: 807 SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPR-PE 865 Query: 183 KQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDI---AKEKRT 239 K P + +P+ P S EP + P + L P PE++ + + Sbjct: 866 KPPEEPGQC-PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPS 924 Query: 240 PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV------KAQPQARMTVPKQTQTPDL 293 +P+ P + P + ++ P P G+L+ + P++ + P Sbjct: 925 LSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAP-------- 976 Query: 294 LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSP--EHLVL 351 LE + P + + P S P L + Q SP +H ++ Sbjct: 977 ---ILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLV 1033 Query: 352 QQKQVQPQLQQEAEPQKQVQP--------------QVHTQAQPSVQPQEHPPAQVSVQPP 397 Q Q A P P ++H V E P + P Sbjct: 1034 PQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE-----P 1088 Query: 398 EQTHEQPHTQPQVSLLAPEQTPVVVHVCGL---EMPPDAVEAGGGMEKTLPEPVGTQVSM 454 T P +S AP P + GL P D ++A G PEP T S+ Sbjct: 1089 SATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQ----PEPGQTPGSL 1144 Query: 455 EEIQNESACGLDVGE 469 S LD E Sbjct: 1145 ASELKGSPVLLDPEE 1159 Score = 37.4 bits (85), Expect = 0.058 Identities = 72/350 (20%), Positives = 121/350 (34%), Gaps = 50/350 (14%) Query: 199 PVEDKSDPPEGSEEAAEPRMDTPEDQDLP----------PCPEDIAKEKRTPAPEPEPCE 248 P+ + PP ++ A+EPR+ + + P PC IA K PAP Sbjct: 3093 PLGPEERPPPAAD-ASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLG 3151 Query: 249 ASELPAKRLRSSEEPTEKEPP----GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 304 P + + S + P G KA A P TP L + +L Sbjct: 3152 LGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLE 3211 Query: 305 RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA 364 +F+ + + T P P+ K++ P L + + ++E Sbjct: 3212 KFE-------LESGALTLPGGPAASGDELDKMESSLVASELP----LLIEDLLEHEKKEL 3260 Query: 365 EPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHV 424 + ++Q+ Q+ Q Q Q+H + +S P Q PH SL +Q Sbjct: 3261 QKKQQLSAQLQPAQQQQQQQQQH--SLLSAPGPAQAMSLPHEGSSPSLAGSQQQL----- 3313 Query: 425 CGLEMPPDAVEAGGGMEKTLPEP-VGTQVSMEEIQNESACGLDVGECENRAREMPGVWGA 483 ++ G + LP+P + TQ +Q A + + N+ + G G Sbjct: 3314 --------SLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAM--VSNQGHMLSGQHGG 3363 Query: 484 GGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 533 L + Q S S P+ +P S+ P + + A FF Sbjct: 3364 QAGL---VPQQSSQPVLSQKPMGTMP---PSMCMKPQQLAMQQQLANSFF 3407 >gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] Length = 2063 Score = 77.8 bits (190), Expect = 4e-14 Identities = 123/474 (25%), Positives = 181/474 (38%), Gaps = 65/474 (13%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ--SPPQAPLP----MAVSR 57 QQQQQQ QQQQQQ QQ QQQQLQ + QQ Q Q Q + Q +P Q P+P S Sbjct: 265 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSG 324 Query: 58 GLPPQQPQQPLLNL---QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTM 114 L P Q L + QG A L G M Q+ L + + PP Y Sbjct: 325 ALQPPPAQGSLGTMTANQGWKKAP-LPGPMQQQLQARPSLATVQTPSHPPPPYPFGS--- 380 Query: 115 PTATLGNLRGYGMASPG----------LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164 A+ + M++PG PS P L P+L P ++ S P Sbjct: 381 QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSP 440 Query: 165 VGVP-MNPSQFNLSGR----NPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMD 219 P +N +Q + R NP Q ++P R M V+ + PP +P Sbjct: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPM-VQQGNVPPNFMVMQQQPPNQ 499 Query: 220 TPED---------QDLPP-------CPEDI-AKEKRTPAPEPEPCEASELPA-KRLRSSE 261 P+ + LPP P + + T A P A +L A + ++ + Sbjct: 500 GPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAG 559 Query: 262 EPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQT 321 P Q+QV P M ++ + +P Q + +Q Q Q Sbjct: 560 GQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVP--QVNLSNMQGQPQQGP 617 Query: 322 QPRIPSTDTQVQPKLQKQAQTQ--TSPEH-LVLQQKQVQPQLQQEAEPQKQVQPQVHTQA 378 ++ Q+ P + Q Q +P++ ++L + Q+ PQ Q P Q Sbjct: 618 PSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQ-------NL 670 Query: 379 QPSVQPQEHPPAQVSVQPPEQTHEQPHTQ---PQVSLLAPEQTPVVVHVCGLEM 429 PS Q P +S Q P+ PH Q PQ +L +Q P++ + +M Sbjct: 671 GPSPQRMTPPKQMLSQQGPQMM--APHNQMMGPQGQVLL-QQNPMIEQIMTNQM 721 Score = 47.0 bits (110), Expect = 7e-05 Identities = 99/444 (22%), Positives = 163/444 (36%), Gaps = 45/444 (10%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-QLQQLLQQSPPQ-----APLPMA 54 M SQQ Q + Q + Q LQQ + +Q + Q+Q QQ Q P P Sbjct: 683 MLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQ 742 Query: 55 VSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGLDQFAMPPATYDTAGL 112 + RG P Q ++ G S +L G + + +QG P+ + Sbjct: 743 IMRGPTPNM-QGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQH 801 Query: 113 TMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQS-------LLGPPPV 165 P T N P + S+ + P++Q + + P Sbjct: 802 GDPATTANNDVSLSQMMPDV---SIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFS 858 Query: 166 GVPMNPSQFNLSGRNPQKQARTSSS-TTPNRKTMPVEDKSDPPEG-SEEAAEPRMDTPED 223 G P N +Q + G+NP + T+P + D S G + + + P+ Sbjct: 859 GAP-NGNQMSC-GQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKK 916 Query: 224 QDLPPCPEDIAKEKRTPAPEPEPCEASE---LPAKRLRSSEEPTEKEPPGQLQVKAQPQA 280 + P ++ ++ TP P E ++ LP ++ + + K P + +P Sbjct: 917 KKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLP----EFSNRPPG 972 Query: 281 RMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA 340 + P + + +P L V P QP Q Q Q+ Q QP PS QP+ Q+Q Sbjct: 973 YPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPS-----QPQSQQQQ 1027 Query: 341 QTQTSPEHLVLQQKQVQ----PQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP 396 Q Q +++ Q+ + P Q P+ + P +Q P +Q P VS+Q Sbjct: 1028 QQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPD--SQRMP-MQQSGSVPVMVSLQG 1084 Query: 397 PEQTHEQPHTQPQVSLLAPEQTPV 420 P P Q + P TP+ Sbjct: 1085 PASVPPSPDKQ---RMPMPVNTPL 1105 Score = 46.2 bits (108), Expect = 1e-04 Identities = 75/289 (25%), Positives = 111/289 (38%), Gaps = 35/289 (12%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL-PPQ 62 QQ Q QL QQQQ Q Q QQQQ QQQ ++ L ++QQ P LP VS+ + PP+ Sbjct: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML--MMQQDPKSVRLP--VSQNVHPPR 1058 Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTAT-LGN 121 P LN +GS+ ++ LQG A P + D + MP T LG+ Sbjct: 1059 GP----LNPDSQRMPMQQSGSV----PVMVSLQGP---ASVPPSPDKQRMPMPVNTPLGS 1107 Query: 122 LRGYGMASPGLAAPSLTP-PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 + PS +P ++A+ P+A+ P G P N + +N Sbjct: 1108 NSRKMVYQESPQNPSSSPLAEMAS------LPEASGSE--APSVPGGPNNMPSHVVLPQN 1159 Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAE----PRMDTPEDQDLPPCPEDIAKE 236 +P T + PP S ++ P + P P P + Sbjct: 1160 QLMMTGPKPGPSPLSATQGATPQ-QPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPR 1218 Query: 237 ---KRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 282 +TP P E SE+ R + PP Q+ + P+ + Sbjct: 1219 PYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPP-QINIPLPPRPNL 1266 Score = 42.0 bits (97), Expect = 0.002 Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 47/208 (22%) Query: 217 RMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPG-QLQVK 275 RM+ P +PP +++ P P PE + PA S + + G +Q + Sbjct: 175 RMNNPATVMIPP-GGNVSSSMMAPGPNPELQPRTPRPA----SQSDAMDPLLSGLHIQQQ 229 Query: 276 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 335 + P + P P + V Q+ P+ Q+Q + Sbjct: 230 SHPSGSLAPPHHPMQP-------------------VSVNRQMN-------PANFPQLQQQ 263 Query: 336 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP-SVQPQEHPPAQVSV 394 Q+Q Q Q QQ+Q Q Q QQ+ + Q + PQ H Q QP ++PQ P QV V Sbjct: 264 QQQQQQQQ--------QQQQQQQQQQQQQQLQAR-PPQQHQQQQPQGIRPQFTAPTQVPV 314 Query: 395 QP-----PEQTHEQPHTQPQVSLLAPEQ 417 P P + P Q + + Q Sbjct: 315 PPGWNQLPSGALQPPPAQGSLGTMTANQ 342 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 76.6 bits (187), Expect = 9e-14 Identities = 89/304 (29%), Positives = 119/304 (39%), Gaps = 56/304 (18%) Query: 5 QQQQQLQQQQQQLQ---QLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61 Q QQQ+QQQQQQLQ QLQ QQ QQQQ QQQQ Q QQ LQ PP PM Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ--QQQQALQAQPPIQQPPM-------- 275 Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121 QQPQ P S LQ+ Q Q Q PP + P + Sbjct: 276 QQPQPP---------PSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQP 326 Query: 122 LRGYGMASPG-----------LAAPSLT--PPQLATPNLQQFFPQATRQSLLGPPPVGVP 168 L A PG + AP + PP QQ Q + + + P V V Sbjct: 327 LVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVS 386 Query: 169 MNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPP 228 + S LS +P +Q +T S P PP+ S + +P + P Sbjct: 387 QS-SLPMLSSPSPGQQVQTPQSMPP------------PPQPSPQPGQPSSQPNSNVSSGP 433 Query: 229 CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 288 P + P+P P+P + S + A+ ++ P+ PG L P + M+ + Sbjct: 434 AP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS----PGPLNTPVNPSSVMSPAGSS 485 Query: 289 QTPD 292 Q + Sbjct: 486 QAEE 489 Score = 69.3 bits (168), Expect = 1e-11 Identities = 91/335 (27%), Positives = 122/335 (36%), Gaps = 31/335 (9%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQ---------LLQLQQLLQQSPPQAP--LP 52 QQQQQQ QQQQQ Q QQQQ QQQQ Q QQ ++Q QQ LQQ Q + Sbjct: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIK 222 Query: 53 MAVSRGLPPQQPQQPL-----LNLQGTNSASLLNGSMLQRALLLQ---QLQGLDQFAMPP 104 + QQ QQ L L LQ Q+AL Q Q + Q PP Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282 Query: 105 ATYDTAGLTMPTATLGNLRGYGMASPGLA--APSLTPPQLATPNLQQFFPQATRQSLLGP 162 + L T + P +A PS PPQ T L Q L Sbjct: 283 SQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342 Query: 163 PPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVE----DKSDPPEGSEEAAEPRM 218 PP+ P PQ Q + ++ T M +S P S + ++ Sbjct: 343 PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQV 402 Query: 219 DTPEDQDLPPCP-----EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQ 273 TP+ PP P + ++ + P P +S LP+ + S+ P P Sbjct: 403 QTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFS 462 Query: 274 VKAQPQARMTV-PKQTQTPDLLPEALEAQVLPRFQ 307 V + V P +P +A E Q L + + Sbjct: 463 VPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLK 497 Score = 64.7 bits (156), Expect = 3e-10 Identities = 88/333 (26%), Positives = 135/333 (40%), Gaps = 61/333 (18%) Query: 241 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 300 AP ++ P +L+ + +++ Q Q + Q QA + +Q Q +A ++ Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194 Query: 301 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 359 + +FQ V Q Q Q Q Q Q + Q Q ++Q+Q Q L LQQ+Q Q Q Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254 Query: 360 LQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 418 QQ+ + Q Q QP + QP +Q + PP+Q Q +Q H H QP P+Q Sbjct: 255 QQQQQQQQALQAQPPIQ---QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQP 308 Query: 419 PVVVHVCGLEMPP---------DAVEAGGGMEKTLP-------------EPVGTQVSMEE 456 PV + ++PP A G M T P PV QV ++ Sbjct: 309 PVAQNQPS-QLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367 Query: 457 IQNESACGLDVGECENRAREM--PGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPS-- 512 ++A +A +M PGV + SL + S + + + P P+PS Sbjct: 368 TAVQTA----------QAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ 417 Query: 513 ---------DSVSSTPAAT-----STPSKQALQ 531 +VSS PA + +PS Q Q Sbjct: 418 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ 450 Score = 31.6 bits (70), Expect = 3.2 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 12/91 (13%) Query: 326 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE---------AEPQKQVQPQVHT 376 P + + P T T L LQQ +Q Q QQ+ + Q+Q Q Q Sbjct: 130 PPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQF 189 Query: 377 QAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 407 QAQ S Q+ Q VQ +Q +Q Q Sbjct: 190 QAQQSAMQQQF---QAVVQQQQQLQQQQQQQ 217 >gi|56549696 E1A binding protein p400 [Homo sapiens] Length = 3122 Score = 71.2 bits (173), Expect = 4e-12 Identities = 119/447 (26%), Positives = 161/447 (36%), Gaps = 76/447 (17%) Query: 8 QQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQP 67 Q L+QQQQQ QQ QQQQ QQQQ QQQQ Q QQ S Q Q P Sbjct: 2715 QLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTS-----------------QVQVP 2757 Query: 68 LLNLQGTNSASL-LNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYG 126 + Q + A + G + L+ Q Q L PP + PTA Sbjct: 2758 QIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQ-------- 2809 Query: 127 MASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLS----GRNPQ 182 + + PPQ +P L ++ P P + + NL R P Sbjct: 2810 -----VQVQTSQPPQQQSPQL---------TTVTAPRPGALLTGTTVANLQVARLTRVPT 2855 Query: 183 KQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 242 Q + + PP S AA + +P LP I+ P Sbjct: 2856 SQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAV--VSSPGVTTLPMNVAGISVAIGQPQK 2913 Query: 243 E------PEPCEASEL-----PAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTP 291 +P +L A + + + +P + P +Q K Q T Q + Sbjct: 2914 AAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVA 2973 Query: 292 DLLPEALEAQVL--PRFQPRVL----QVQAQVQSQTQPRIPSTDTQVQPKLQ-KQAQTQT 344 AL+ Q L P Q + L QVQ Q+Q P++ T V Q A Q Sbjct: 2974 YAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQA 3033 Query: 345 SPEHLVL-------QQKQVQPQLQQEAE--PQKQVQPQVHTQAQPSVQPQEHP-PAQV-- 392 SP+ + L QQ Q+ P + A+ QK +Q QV T A +Q P PAQV Sbjct: 3034 SPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPA 3093 Query: 393 SVQPPEQTHEQPHTQPQVSLLAPEQTP 419 S P Q + P V L P + P Sbjct: 3094 SSDSPSQQPKLQMRVPAVRLKTPTKPP 3120 Score = 64.7 bits (156), Expect = 3e-10 Identities = 105/454 (23%), Positives = 154/454 (33%), Gaps = 80/454 (17%) Query: 16 QLQQLQQQQLQQQQ--LQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQG 73 Q+ L+ +++ +++ L QQ Q + Q PPQ P PPQQP PL Q Sbjct: 2476 QVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPP------PPQQPPPPLPQPQA 2529 Query: 74 TNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLA 133 GS Q Q Q P P T G G G Sbjct: 2530 A-------GSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTG---GSAAVLAGTI 2579 Query: 134 APSLTPPQLAT--------PNLQQFFPQATRQSL-------LGPPPVGVPMNPSQFNLSG 178 S+T + T N P AT QS+ + P + P + + Sbjct: 2580 KTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVH 2639 Query: 179 RNPQKQARTSSST-TPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 237 P +A S +T TP+ +M +G +L P + Sbjct: 2640 TQPPPRAVGSPATATPDLVSMAT------TQGVRAVTSVTASAVVTTNLTP----VQTPA 2689 Query: 238 RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEA 297 R+ P+ +LP K + P Q+ Q Q + +Q Q Sbjct: 2690 RSLVPQVSQATGVQLPGKTI----------TPAHFQLLRQQQQQQQQQQQQQ-------- 2731 Query: 298 LEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ 357 Q + Q + Q Q Q + +Q ++P Q Q Q +A + +PEHL+ QKQ Sbjct: 2732 ---QQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKL 2788 Query: 358 PQLQQEAEPQKQ---VQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLA 414 Q PQ Q QP Q Q S PQ+ P +V T P+ L Sbjct: 2789 QMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTV-----------TAPRPGALL 2837 Query: 415 PEQTPVVVHVCGL-EMPPDAVEAGGGMEKTLPEP 447 T + V L +P ++A G M+ P+P Sbjct: 2838 TGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQP 2871 Score = 38.9 bits (89), Expect = 0.020 Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 28/120 (23%) Query: 223 DQDLPPCP------EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 276 D+ LPP E IAKEK+ A + + +++P +PP Sbjct: 2469 DKPLPPIQVASLRAERIAKEKKALADQ--------------QKAQQPAVAQPP------- 2507 Query: 277 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 336 PQ + P Q Q P LP+ A P P +Q Q Q Q QTQP+ + QP + Sbjct: 2508 PPQPQPPPPPQ-QPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAI 2566 Score = 34.3 bits (77), Expect = 0.49 Identities = 64/313 (20%), Positives = 102/313 (32%), Gaps = 51/313 (16%) Query: 291 PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV 350 P + +L A+ + + + + L Q + Q + P Q P Q+ P+ Sbjct: 2473 PPIQVASLRAERIAK-EKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAG 2531 Query: 351 LQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQV 410 Q P +Q + +PQ Q QPQ VQ P + T Sbjct: 2532 SQPPAGPPAVQPQPQPQPQTQPQ-------------------PVQAPAKAQPAITTGGSA 2572 Query: 411 SLLAPEQTPVVVHVCGLEMPPDAVEAG--------------GGMEKTLPEPVGTQV---- 452 ++LA + V G MP AV + K L PV Sbjct: 2573 AVLA---GTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTP 2629 Query: 453 ---SMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVP 509 + ++ + VG ++ + G VT + +S A T LTPV Sbjct: 2630 GGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTAS---AVVTTNLTPVQ 2686 Query: 510 RPSDSV---SSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHM 566 P+ S+ S P K + + QQ+ Q + Q QQ+ + Q Sbjct: 2687 TPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQ-QQQQQQQQQQQQQQQQQQQQQQQQQ 2745 Query: 567 SQACLLSLLPVPR 579 Q S + VP+ Sbjct: 2746 QQTTTTSQVQVPQ 2758 Score = 33.9 bits (76), Expect = 0.64 Identities = 48/183 (26%), Positives = 72/183 (39%), Gaps = 17/183 (9%) Query: 17 LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP--PQQPQQPLLNLQGT 74 LQ QQ Q+ + Q Q Q ++ QQ P P+P S LP P QP Q L++ T Sbjct: 574 LQFAQQPQVVEAQTQLQIPVKTQQ------PNVPIPAPPSSQLPIPPSQPAQLALHVP-T 626 Query: 75 NSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGL-TMPTATLGNLRGYGMA-SPGL 132 + S L L Q+ + + PA L T T++L + G G SP Sbjct: 627 PGKVQVQASQLSS---LPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPAR 683 Query: 133 AAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTT 192 ++P P L P +R + P +P+Q S ++ + T T Sbjct: 684 SSPVNRPSSATNKALS---PVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQITL 740 Query: 193 PNR 195 N+ Sbjct: 741 ENQ 743 Score = 32.3 bits (72), Expect = 1.9 Identities = 76/291 (26%), Positives = 102/291 (35%), Gaps = 59/291 (20%) Query: 308 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHL--------VLQQKQVQPQ 359 P+ Q+ Q QSQ Q PST VQ P L L Q Sbjct: 520 PQAAQLAGQRQSQQQYD-PSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQ 578 Query: 360 LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHE---QPHTQPQVSLLAPE 416 Q E Q Q+Q V TQ QP+V P PP+ PP Q + T +V + A + Sbjct: 579 QPQVVEAQTQLQIPVKTQ-QPNV-PIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQ 636 Query: 417 QTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRARE 476 + + V +P D P P+ T S + S G Sbjct: 637 LSSLPQMVASTRLPVDPA-------PPCPRPLPTS-STSSLAPVSGSG------------ 676 Query: 477 MPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYI 536 PG A S V S+ ++A S V R V+S P +P++ A Sbjct: 677 -PGPSPARSS-PVNRPSSATNKALSPV----TSRTPGVVASAPTKPQSPAQNA------- 723 Query: 537 CKASCSSQQEFQDHMSEP-----QHQQRLGEIQH---MSQACLLSLLPVPR 579 SSQ QD ++E Q QR+ E++ SQ L L PR Sbjct: 724 ----TSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPR 770 Score = 31.6 bits (70), Expect = 3.2 Identities = 46/180 (25%), Positives = 64/180 (35%), Gaps = 35/180 (19%) Query: 125 YGMASPG--LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPV------------GVPMN 170 YG G +A PS PP+ A P PQ L G PP+ P Sbjct: 1432 YGQKPEGRTVAFPSTHPPRTAAPTTASAAPQG---PLRGRPPIATFSANPEAKAAAAPFQ 1488 Query: 171 PSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCP 230 SQ + S P+ Q ++SST + P + + +A+ P P+ P P Sbjct: 1489 TSQASASA--PRHQPASASSTAAS----PAHPAKLRAQTTAQASTPGQPPPQ----PQAP 1538 Query: 231 EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQT 290 A + P P +A RL S E QL PQ+R+ P+ T Sbjct: 1539 SHAAGQSALPQRLVLPSQAQ----ARLPSG----EVVKIAQLASITGPQSRVAQPETPVT 1590 >gi|38788274 bromodomain PHD finger transcription factor isoform 1 [Homo sapiens] Length = 2920 Score = 68.9 bits (167), Expect = 2e-11 Identities = 81/312 (25%), Positives = 123/312 (39%), Gaps = 62/312 (19%) Query: 153 QATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQAR--------TSSSTTPNRKTMPVEDKS 204 Q T Q L P V V P Q + P + T+++T T + Sbjct: 2174 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAA 2233 Query: 205 DPPEGSEEAAEPRMDTPEDQDLPPC------PEDIAKEKRTPAPEPEPCEASELPAK--- 255 E + P+M +D+ LPP P + + P+ +P+P + PA+ Sbjct: 2234 GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEV 2293 Query: 256 ---------RLRSSEEPTEKEPPG------QLQVKAQPQA--------RMTVPKQTQ--- 289 SS P+E +P Q+ ++QPQ+ R+ P QT+ Sbjct: 2294 QTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRP 2353 Query: 290 -TPDLLPEALEAQVLPR------FQPRV-LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQ 341 TP L ++QV QP LQ+ +Q Q Q+QP++ S+ + Sbjct: 2354 STPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQV 2413 Query: 342 TQTSPEHLVLQQKQVQ------PQLQQEAEPQKQVQPQV--HTQAQPSVQPQE---HPPA 390 T +SP LQ +Q Q PQLQQ+ + Q+Q QV QAQ S PQ+ P Sbjct: 2414 TVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPI 2473 Query: 391 QVSVQPPEQTHE 402 Q+ QTH+ Sbjct: 2474 QIQQSSAVQTHQ 2485 Score = 65.9 bits (159), Expect = 2e-10 Identities = 49/157 (31%), Positives = 73/157 (46%), Gaps = 11/157 (7%) Query: 277 QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 335 Q Q++++ Q LP A + V P QP+ Q AQ Q QTQP+ P+ QP+ Sbjct: 2238 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2292 Query: 336 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--KQVQPQVHTQAQPSVQPQEHPPAQVS 393 +Q Q + QT + QP Q ++PQ Q QPQ + Q Q V+ Q P+Q Sbjct: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQS--PSQTR 2350 Query: 394 VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 430 ++P + P Q QV + P+ H L++P Sbjct: 2351 IRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2386 Score = 59.3 bits (142), Expect = 1e-08 Identities = 103/439 (23%), Positives = 177/439 (40%), Gaps = 55/439 (12%) Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62 S Q + QQ Q +L Q QL Q Q L + Q Q+ Q L LP Sbjct: 2133 SASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPG- 2191 Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNL 122 P Q L+ A++ NG++ QR L P AT T T T Sbjct: 2192 -PGQQLMQ------AAMPNGTV-QRFLFT-----------PLATTATTASTTTTTVSTTA 2232 Query: 123 RGYGMASPGLAAP--------SLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQF 174 G G +P +L P Q ++ + PQ T Q P P P +P+Q Sbjct: 2233 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQ-TAQPSAQPQPQTQPQSPAQP 2291 Query: 175 NLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEA---------AEPRMDTPEDQD 225 + + P+ Q +T+ S+ + P +S P+ + ++ + R+ +P Sbjct: 2292 EVQTQ-PEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTR 2350 Query: 226 L-PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTV 284 + P P ++ +++ + + + +P + S + P++ +P Q QV++ Q + Sbjct: 2351 IRPSTPSQLSPGQQS---QVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSG 2407 Query: 285 PKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 344 Q P + Q+ + QP+V+ V Q+Q Q Q +Q+Q ++ Q Q Q Sbjct: 2408 QTLNQVTVSSPSRPQLQI-QQPQPQVIAVP-QLQQQVQVL-----SQIQSQVVAQIQAQQ 2460 Query: 345 S--PEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHE 402 S P+ + LQ + Q+QQ + Q V T SVQ Q Q+ Q ++ + Sbjct: 2461 SGVPQQIKLQ---LPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQ 2517 Query: 403 QPHTQPQVSLLAPEQTPVV 421 Q + + +L A Q+ ++ Sbjct: 2518 QIEIKREHTLQASNQSEII 2536 Score = 31.6 bits (70), Expect = 3.2 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%) Query: 648 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 700 + D E + E+++ ++E+ +GD EE +D ED+EE E+EE+ Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169 Score = 30.0 bits (66), Expect = 9.3 Identities = 17/60 (28%), Positives = 26/60 (43%) Query: 227 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 286 P P A E+ PAP P P + P LRS + + Q + P+ R++ P+ Sbjct: 9 PKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPR 68 >gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens] Length = 858 Score = 67.0 bits (162), Expect = 7e-11 Identities = 122/471 (25%), Positives = 165/471 (35%), Gaps = 88/471 (18%) Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64 Q QQ+ QQQ LQ LQQQ L QL L + Q S + Q P Sbjct: 73 QYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGSNVSAQAP 132 Query: 65 QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRG 124 Q S+S+ + A LL + Q ++ A +G+ LGN Sbjct: 133 AQ---------SSSINLAASPAAAQLLNRAQSVNSAA-------ASGIAQQAVLLGN--- 173 Query: 125 YGMASPGLAAPSLTPPQLATPNLQQFFPQ---ATRQSLLGPPPVGVPMNPSQF-NLSGRN 180 +SP L A + F P AT Q LG P P+Q NL+ R Sbjct: 174 --TSSPALTASQ--AQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRT 229 Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240 Q A +S TP + +P P GS Q LP TP Sbjct: 230 QQTPAAAASGPTPTQPVLPSLALKPTPGGS-------------QPLP-----------TP 265 Query: 241 APEPEPCEASELPAK-RLRSSEEPTEKEPPGQLQVKAQPQAR----MTVPKQTQTPDLLP 295 A +AS AK + S K+ G V + R TVP P + P Sbjct: 266 AQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAP 325 Query: 296 EALEA---QVLPRFQPRVLQVQAQVQSQTQPRIPS-TDTQVQPKLQKQAQTQTSPEHLVL 351 + Q+LP+ + LQ Q +Q Q QP+ Q +P LQ + Q + V Sbjct: 326 AYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLAS---VS 382 Query: 352 QQKQVQPQLQQEAEPQKQVQPQVHTQA------QPSVQPQEHPPAQVSVQPPEQTHEQ-- 403 +QP + A P V P + Q +P Q HPP + P+ H + Sbjct: 383 PSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDT--GPQNGHPEGV 440 Query: 404 --------PHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPE 446 HT + L P P C +P D E G EK++PE Sbjct: 441 PHTPQRRFQHTSAVILQLQPASPP---QQC---VPDDWKEVAPG-EKSVPE 484 >gi|91208418 transcription elongation regulator 1 isoform 2 [Homo sapiens] Length = 1077 Score = 66.2 bits (160), Expect = 1e-10 Identities = 71/255 (27%), Positives = 90/255 (35%), Gaps = 28/255 (10%) Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDT 220 GPPP+ P P P + PN MP PP G P Sbjct: 42 GPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMP 101 Query: 221 PEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQA 280 P +PP P + P P A PA K P G++ A Sbjct: 102 PPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY---NA 152 Query: 281 RMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA 340 R T+ PD + ++++ P +L QAQVQ+Q Q + Q Q + Q QA Sbjct: 153 RTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQAQ-----AQAQAQAQAQA 201 Query: 341 QTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQT 400 Q Q Q Q Q Q Q +A+ Q Q Q Q QAQ Q Q Q VQ Q Sbjct: 202 QAQA--------QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQA 253 Query: 401 HEQPHTQPQVSLLAP 415 + P S AP Sbjct: 254 QAVGASTPTTSSPAP 268 Score = 54.7 bits (130), Expect = 4e-07 Identities = 75/345 (21%), Positives = 122/345 (35%), Gaps = 43/345 (12%) Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 189 P + P PP + P+LQ R + PP +P P G P T + Sbjct: 77 PPMPPPGGIPPPMGPPHLQ-------RPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPA 129 Query: 190 STTPNRKTMPVEDKSDPPEG--------SEEAAEPRMD---TPEDQDLPP---CPEDIAK 235 P + + VE+K+ P+G + E+A + D + +L P + Sbjct: 130 --LPPTEEIWVENKT--PDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQA 185 Query: 236 EKRTPAPEPEPCEA---SELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPD 292 + + A +A ++ A+ ++ + + Q Q +AQ QA+ Q Q Sbjct: 186 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQA 245 Query: 293 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 352 + ++AQ + P V + T PS+ T AQT ++P Sbjct: 246 QVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTP----TT 301 Query: 353 QKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL 412 Q Q A P V T PQ HP PP PH+ PQ + Sbjct: 302 QDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHP----QTLPP----AVPHSVPQPTT 353 Query: 413 LAPEQTPVVVHVCGLEMPPDAVEAGG---GMEKTLPEPVGTQVSM 454 P PV+V + +P + G GM + + QV++ Sbjct: 354 AIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAI 398 Score = 39.7 bits (91), Expect = 0.012 Identities = 72/314 (22%), Positives = 107/314 (34%), Gaps = 55/314 (17%) Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64 Q Q Q Q Q Q Q Q Q Q Q+Q Q Q+Q AV P Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQ------------AQAVGASTPTTSS 265 Query: 65 QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYD---TAGLTMPTATLGN 121 P ++ ++S S A + Q P T D ++ +++ T T+ Sbjct: 266 PAPAVSTSTSSSTPSSTTSTTTTA------TSVAQTVSTPTTQDQTPSSAVSVATPTVSV 319 Query: 122 LRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGP----PPVGVPMNPSQFNLS 177 A+P P PQ P + PQ T P PP VP+ L Sbjct: 320 STPAPTATPVQTVPQ-PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLP 378 Query: 178 G------------RNPQKQARTSSSTTPNRKTMPVEDKSDPPEG-----SEEAAEPRMDT 220 G +PQ S +T + + +G + E + Sbjct: 379 GVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEK 438 Query: 221 PED-QDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEKEPPGQ 271 P++ ++ E I + + P+ EP P E E P K ++ EE TE+E Q Sbjct: 439 PQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQ 498 Query: 272 LQVKAQPQARMTVP 285 KA+P A +P Sbjct: 499 ---KAKPVATAPIP 509 >gi|21327715 transcription elongation regulator 1 isoform 1 [Homo sapiens] Length = 1098 Score = 66.2 bits (160), Expect = 1e-10 Identities = 71/255 (27%), Positives = 90/255 (35%), Gaps = 28/255 (10%) Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDT 220 GPPP+ P P P + PN MP PP G P Sbjct: 42 GPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMP 101 Query: 221 PEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQA 280 P +PP P + P P A PA K P G++ A Sbjct: 102 PPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY---NA 152 Query: 281 RMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA 340 R T+ PD + ++++ P +L QAQVQ+Q Q + Q Q + Q QA Sbjct: 153 RTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQAQ-----AQAQAQAQAQA 201 Query: 341 QTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQT 400 Q Q Q Q Q Q Q +A+ Q Q Q Q QAQ Q Q Q VQ Q Sbjct: 202 QAQA--------QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQA 253 Query: 401 HEQPHTQPQVSLLAP 415 + P S AP Sbjct: 254 QAVGASTPTTSSPAP 268 Score = 54.7 bits (130), Expect = 4e-07 Identities = 97/481 (20%), Positives = 170/481 (35%), Gaps = 84/481 (17%) Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 189 P + P PP + P+LQ R + PP +P P G P T + Sbjct: 77 PPMPPPGGIPPPMGPPHLQ-------RPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPA 129 Query: 190 STTPNRKTMPVEDKSDPPEG--------SEEAAEPRMD---TPEDQDLPP---CPEDIAK 235 P + + VE+K+ P+G + E+A + D + +L P + Sbjct: 130 --LPPTEEIWVENKT--PDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQA 185 Query: 236 EKRTPAPEPEPCEA---SELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPD 292 + + A +A ++ A+ ++ + + Q Q +AQ QA+ Q Q Sbjct: 186 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQA 245 Query: 293 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 352 + ++AQ + P V + T PS+ T AQT ++P Sbjct: 246 QVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTP----TT 301 Query: 353 QKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL 412 Q Q A P V T PQ HP PP PH+ PQ + Sbjct: 302 QDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHP----QTLPP----AVPHSVPQPTT 353 Query: 413 LAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECEN 472 P PV+V PP V G +P P+ M+ + +C Sbjct: 354 AIPAFPPVMV-------PPFRVPLPG-----MPIPLPGVAMMQIV----SCPYVKTVATT 397 Query: 473 RAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPA--ATSTPSKQAL 530 + +PG+ P+ P+ P +++++PA A +T + Sbjct: 398 KTGVLPGM---------------------APPIVPMIHPQVAIAASPATLAGATAVSEWT 436 Query: 531 QFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLL--SLLPVPRDVLETEDEE 588 ++ K + + + +PQ + +++ + + S P+P +ETE+E+ Sbjct: 437 EYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLP---METEEED 493 Query: 589 P 589 P Sbjct: 494 P 494 Score = 33.5 bits (75), Expect = 0.84 Identities = 74/319 (23%), Positives = 111/319 (34%), Gaps = 44/319 (13%) Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62 Q Q Q Q Q Q Q Q Q Q Q+Q Q Q+Q Q + S P P AVS Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277 Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMP------PATYDTAGLTMP- 115 P T +A+ + ++ Q A P PA T T+P Sbjct: 278 TPSS---TTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQ 334 Query: 116 --TATLGNLRGYGMASPGLAAPS----LTPP-QLATPNLQQFFPQATRQSLLGPPPVGVP 168 TL + + P A P+ + PP ++ P + P ++ P V Sbjct: 335 PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTV 394 Query: 169 MNPSQFNLSGR--------NPQKQARTSSSTTPNRKTMPVEDKSDPPEG-----SEEAAE 215 L G +PQ S +T + + +G + E Sbjct: 395 ATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLE 454 Query: 216 PRMDTPED-QDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEK 266 + P++ ++ E I + + P+ EP P E E P K ++ EE TE+ Sbjct: 455 STWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEE 514 Query: 267 EPPGQLQVKAQPQARMTVP 285 E Q KA+P A +P Sbjct: 515 EKAAQ---KAKPVATAPIP 530 >gi|38788260 bromodomain PHD finger transcription factor isoform 2 [Homo sapiens] Length = 2903 Score = 65.9 bits (159), Expect = 2e-10 Identities = 49/157 (31%), Positives = 73/157 (46%), Gaps = 11/157 (7%) Query: 277 QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 335 Q Q++++ Q LP A + V P QP+ Q AQ Q QTQP+ P+ QP+ Sbjct: 2364 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2418 Query: 336 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--KQVQPQVHTQAQPSVQPQEHPPAQVS 393 +Q Q + QT + QP Q ++PQ Q QPQ + Q Q V+ Q P+Q Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQS--PSQTR 2476 Query: 394 VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 430 ++P + P Q QV + P+ H L++P Sbjct: 2477 IRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2512 Score = 61.6 bits (148), Expect = 3e-09 Identities = 67/271 (24%), Positives = 100/271 (36%), Gaps = 41/271 (15%) Query: 153 QATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQAR--------TSSSTTPNRKTMPVEDKS 204 Q T Q L P V V P Q + P + T+++T T + Sbjct: 2300 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAA 2359 Query: 205 DPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPT 264 E + P+M +D+ LPP P EA A+ + T Sbjct: 2360 GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG----------PAEAQPQTAQPSAQPQPQT 2409 Query: 265 EKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL---QVQAQVQSQT 321 + + P Q +V+ QP+ V QT +P + +P+V Q Q+ VQ Q+ Sbjct: 2410 QPQSPAQPEVQTQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQS 2465 Query: 322 QPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPS 381 R+ S Q +++ +Q SP QQ QVQ Q Q Q+ +Q QP Sbjct: 2466 PVRVQSPS---QTRIRPSTPSQLSPG----QQSQVQTTTSQPIPIQPHTSLQIPSQGQPQ 2518 Query: 382 VQPQ---------EHPPAQVSVQPPEQTHEQ 403 QPQ EH + S+ P E+ Q Sbjct: 2519 SQPQVVMKHNAVIEHLKQKKSMTPAEREENQ 2549 Score = 43.1 bits (100), Expect = 0.001 Identities = 40/143 (27%), Positives = 50/143 (34%), Gaps = 8/143 (5%) Query: 270 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 329 GQLQ+ Q + P Q L+ A+ + RF L A S T + +T Sbjct: 2303 GQLQLIPQGVTVLPGPGQ----QLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTA 2358 Query: 330 T----QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQ 385 Q Q KL Q Q Q V P Q Q QPQ TQ Q QP+ Sbjct: 2359 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2418 Query: 386 EHPPAQVSVQPPEQTHEQPHTQP 408 +V Q +H QP Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQP 2441 Score = 31.6 bits (70), Expect = 3.2 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%) Query: 648 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 700 + D E + E+++ ++E+ +GD EE +D ED+EE E+EE+ Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169 Score = 30.0 bits (66), Expect = 9.3 Identities = 17/60 (28%), Positives = 26/60 (43%) Query: 227 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 286 P P A E+ PAP P P + P LRS + + Q + P+ R++ P+ Sbjct: 9 PKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPR 68 >gi|17017963 forkhead box P2 isoform I [Homo sapiens] Length = 715 Score = 65.5 bits (158), Expect = 2e-10 Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%) Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64 QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ P + QQ Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 206 Query: 65 QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113 QQ L Q LL LQ+ LL Q QGL Q A+P + AGL+ Sbjct: 207 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 262 Score = 55.1 bits (131), Expect = 3e-07 Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 20/159 (12%) Query: 260 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQ 318 S + ++K+ P Q+ V A MT Q TP + + L+ QVL P+ +LQ Q V Sbjct: 75 SPKSSDKQRPLQVPVSV---AMMT--PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVM 129 Query: 319 SQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQA 378 Q Q Q+Q +KQ E L LQ Q Q Q QQ+ + Q+Q Q Q Q Sbjct: 130 LQQQ--------QLQEFYKKQQ------EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175 Query: 379 QPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQ 417 Q Q Q+ Q P +Q EQ Q Q LA +Q Sbjct: 176 QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214 Score = 49.3 bits (116), Expect = 1e-05 Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%) Query: 5 QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61 QQQQ + QQQQLQ+ QQ+QL Q LQQQQ Q QQ QQ Q + Sbjct: 123 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 182 Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121 QQ QQ G + Q+ L QQL Q L + Sbjct: 183 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 235 Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155 L+ G+ S PG AA SL L+ +QQ + + T Sbjct: 236 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 274 Score = 43.9 bits (102), Expect = 6e-04 Identities = 37/136 (27%), Positives = 54/136 (39%), Gaps = 3/136 (2%) Query: 273 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQV---QAQVQSQTQPRIPSTD 329 QV Q + + +Q +P L L+ Q Q + LQ + Q Q Q Sbjct: 97 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 156 Query: 330 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPP 389 Q Q + Q+Q Q Q + QQ+Q Q Q QQ+ P KQ + Q Q Q + Sbjct: 157 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 216 Query: 390 AQVSVQPPEQTHEQPH 405 Q + +Q +Q H Sbjct: 217 FQQQLLQMQQLQQQQH 232 Score = 36.2 bits (82), Expect = 0.13 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 12/126 (9%) Query: 296 EALEA--QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 353 +AL+A Q+L + Q L+ Q ++P + + P++ Q Q + VL Sbjct: 56 QALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSP 115 Query: 354 KQVQPQLQQE----------AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQ 403 +Q+Q LQQ+ E K+ Q Q+H Q Q Q+ Q Q +Q +Q Sbjct: 116 QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175 Query: 404 PHTQPQ 409 Q Q Sbjct: 176 QQQQQQ 181 Score = 33.5 bits (75), Expect = 0.84 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 6/86 (6%) Query: 12 QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAV--SRGLPPQQPQQPLL 69 QQQQ LQ +Q LQQQ L + +Q P Q P+ +A+ + + PQQ QQ +L Sbjct: 53 QQQQALQAARQLLLQQQT---SGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQ-IL 108 Query: 70 NLQGTNSASLLNGSMLQRALLLQQLQ 95 Q + L Q+A++LQQ Q Sbjct: 109 QQQVLSPQQLQALLQQQQAVMLQQQQ 134 Score = 31.2 bits (69), Expect = 4.2 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58 QQ QQ LQQQ QQLQ LQQQQ + QLQ+ ++ Q L + + Sbjct: 102 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155 Query: 59 LPPQQPQQ 66 QQ QQ Sbjct: 156 QQQQQQQQ 163 >gi|22538413 forkhead box P2 isoform III [Homo sapiens] Length = 623 Score = 65.5 bits (158), Expect = 2e-10 Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%) Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64 QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ P + QQ Sbjct: 60 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 114 Query: 65 QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113 QQ L Q LL LQ+ LL Q QGL Q A+P + AGL+ Sbjct: 115 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 170 Score = 52.0 bits (123), Expect = 2e-06 Identities = 45/132 (34%), Positives = 58/132 (43%), Gaps = 15/132 (11%) Query: 287 QTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS 345 Q TP + + L+ QVL P+ +LQ Q V Q Q Q+Q +KQ Sbjct: 5 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQ--------QLQEFYKKQQ----- 51 Query: 346 PEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 405 E L LQ Q Q Q QQ+ + Q+Q Q Q Q Q Q Q+ Q P +Q EQ Sbjct: 52 -EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 110 Query: 406 TQPQVSLLAPEQ 417 Q Q LA +Q Sbjct: 111 QQQQQQQLAAQQ 122 Score = 49.3 bits (116), Expect = 1e-05 Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%) Query: 5 QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61 QQQQ + QQQQLQ+ QQ+QL Q LQQQQ Q QQ QQ Q + Sbjct: 31 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 90 Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121 QQ QQ G + Q+ L QQL Q L + Sbjct: 91 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 143 Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155 L+ G+ S PG AA SL L+ +QQ + + T Sbjct: 144 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 182 Score = 46.6 bits (109), Expect = 1e-04 Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 34/241 (14%) Query: 273 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 332 QV Q + + +Q +P L L+ Q Q + LQ + + Q ++ Q Sbjct: 5 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ---EFYKKQQEQLHLQLLQQ 61 Query: 333 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 392 Q + Q+Q Q Q + QQ+Q Q Q QQ+ + Q+Q P + Q Q Q+ A Sbjct: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 121 Query: 393 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQV 452 + +Q + Q Q LL+ ++ ++ +PP + LP Sbjct: 122 QLVFQQQLLQMQQLQQQQHLLSLQRQGLI------SIPPG--------QAALP------- 160 Query: 453 SMEEIQNESACGLDVGECENRAREMPGVWG------AGGSLKVTILQSSDSRAFSTVPLT 506 +Q+ GL E + +E+ GV G L +T SS + + +T + Sbjct: 161 ----VQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKAS 216 Query: 507 P 507 P Sbjct: 217 P 217 Score = 38.9 bits (89), Expect = 0.020 Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%) Query: 269 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 320 P QLQ Q Q + + +Q Q L + L+ Q + Q + Q Q Q Q Q Sbjct: 23 PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 82 Query: 321 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 380 Q Q Q + Q+Q Q Q P +Q+Q Q Q QQ A Q Q Q+ Q Sbjct: 83 QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ- 134 Query: 381 SVQPQEH-----PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 435 +Q Q+H +S+ PP Q + PQ L E + V G+ D Sbjct: 135 -LQQQQHLLSLQRQGLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGI 192 Query: 436 AGGGMEKT 443 GG++ T Sbjct: 193 KHGGLDLT 200 Score = 31.2 bits (69), Expect = 4.2 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58 QQ QQ LQQQ QQLQ LQQQQ + QLQ+ ++ Q L + + Sbjct: 10 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 63 Query: 59 LPPQQPQQ 66 QQ QQ Sbjct: 64 QQQQQQQQ 71 >gi|149999352 forkhead box P2 isoform II [Homo sapiens] Length = 740 Score = 65.5 bits (158), Expect = 2e-10 Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%) Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64 QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ P + QQ Sbjct: 177 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 231 Query: 65 QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113 QQ L Q LL LQ+ LL Q QGL Q A+P + AGL+ Sbjct: 232 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 287 Score = 52.8 bits (125), Expect = 1e-06 Identities = 47/143 (32%), Positives = 62/143 (43%), Gaps = 15/143 (10%) Query: 276 AQPQARMTVPKQTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 334 A P + + Q TP + + L+ QVL P+ +LQ Q V Q Q Q+Q Sbjct: 111 AVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQ--------QLQE 162 Query: 335 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSV 394 +KQ E L LQ Q Q Q QQ+ + Q+Q Q Q Q Q Q Q+ Q Sbjct: 163 FYKKQQ------EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 216 Query: 395 QPPEQTHEQPHTQPQVSLLAPEQ 417 P +Q EQ Q Q LA +Q Sbjct: 217 HPGKQAKEQQQQQQQQQQLAAQQ 239 Score = 49.3 bits (116), Expect = 1e-05 Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%) Query: 5 QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61 QQQQ + QQQQLQ+ QQ+QL Q LQQQQ Q QQ QQ Q + Sbjct: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 207 Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121 QQ QQ G + Q+ L QQL Q L + Sbjct: 208 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 260 Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155 L+ G+ S PG AA SL L+ +QQ + + T Sbjct: 261 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 299 Score = 46.6 bits (109), Expect = 1e-04 Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 34/241 (14%) Query: 273 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 332 QV Q + + +Q +P L L+ Q Q + LQ + + Q ++ Q Sbjct: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ---EFYKKQQEQLHLQLLQQ 178 Query: 333 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 392 Q + Q+Q Q Q + QQ+Q Q Q QQ+ + Q+Q P + Q Q Q+ A Sbjct: 179 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 238 Query: 393 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQV 452 + +Q + Q Q LL+ ++ ++ +PP + LP Sbjct: 239 QLVFQQQLLQMQQLQQQQHLLSLQRQGLI------SIPPG--------QAALP------- 277 Query: 453 SMEEIQNESACGLDVGECENRAREMPGVWG------AGGSLKVTILQSSDSRAFSTVPLT 506 +Q+ GL E + +E+ GV G L +T SS + + +T + Sbjct: 278 ----VQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKAS 333 Query: 507 P 507 P Sbjct: 334 P 334 Score = 38.9 bits (89), Expect = 0.020 Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%) Query: 269 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 320 P QLQ Q Q + + +Q Q L + L+ Q + Q + Q Q Q Q Q Sbjct: 140 PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 199 Query: 321 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 380 Q Q Q + Q+Q Q Q P +Q+Q Q Q QQ A Q Q Q+ Q Sbjct: 200 QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ- 251 Query: 381 SVQPQEH-----PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 435 +Q Q+H +S+ PP Q + PQ L E + V G+ D Sbjct: 252 -LQQQQHLLSLQRQGLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGI 309 Query: 436 AGGGMEKT 443 GG++ T Sbjct: 310 KHGGLDLT 317 Score = 31.2 bits (69), Expect = 4.2 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58 QQ QQ LQQQ QQLQ LQQQQ + QLQ+ ++ Q L + + Sbjct: 127 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180 Query: 59 LPPQQPQQ 66 QQ QQ Sbjct: 181 QQQQQQQQ 188 >gi|118498345 AT-binding transcription factor 1 [Homo sapiens] Length = 3703 Score = 64.3 bits (155), Expect = 4e-10 Identities = 86/321 (26%), Positives = 120/321 (37%), Gaps = 44/321 (13%) Query: 130 PGLAAPSL---TPPQLAT----PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 182 PGL +PSL TP A PNL P T S G P G+P PS +LS P Sbjct: 3127 PGLNSPSLPGFTPSNTALTSPKPNLMGL-PSTTVPSP-GLPTSGLPNKPSSASLSSPTPA 3184 Query: 183 KQARTSSSTTP----NRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKR 238 + P ++ P + PP ++ P++ + Q + KEK Sbjct: 3185 QATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKE 3244 Query: 239 ---------TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ 289 P P+ E EA A + S+ PT + Q++A A + P Sbjct: 3245 KAHKGKGEPLPVPKKEKGEAPTATAATI-SAPLPTMEYAVDPAQLQALQAALTSDPTALL 3303 Query: 290 TPDLLPEALEAQVLPRFQPRVL-QVQAQVQS-QTQPRIPSTDTQVQPKLQKQAQTQTSPE 347 T LP +P F P Q+ +QS QP QA SP Sbjct: 3304 TSQFLP-----YFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPG 3358 Query: 348 HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP----------- 396 L+ Q +Q Q LQ+ Q+Q Q Q+ Q Q VQ Q+ +Q V P Sbjct: 3359 SLLQQYQQYQQSLQEAI--QQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAK 3416 Query: 397 -PEQTHEQPHTQPQVSLLAPE 416 + EQ +T +VS L P+ Sbjct: 3417 ESPKPEEQKNTPREVSPLLPK 3437 Score = 57.0 bits (136), Expect = 7e-08 Identities = 109/441 (24%), Positives = 150/441 (34%), Gaps = 56/441 (12%) Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62 S+QQQQQ QQQQQQ QQ QQQ Q Q Q LQQ LQQ Sbjct: 1721 SRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQ------------------ 1762 Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALL-LQQLQG-LDQFAMPPATYDTAGLTMPTATLG 120 Q L+ Q N L + M LL LQQ Q L F +P A + T G Sbjct: 1763 --QAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSG 1820 Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 L G PGL Q+ + QQ PQ + L + PSQ + Sbjct: 1821 ALTLTG-TGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQ------H 1873 Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240 P+K+ + K + + D EG E P+ + LP + K++ P Sbjct: 1874 PEKK----NKLVIKEKEKESQRERDSAEGGEGNTGPK------ETLPDALKAKEKKELAP 1923 Query: 241 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP--EAL 298 EP A R + E G V + + V K+ D E L Sbjct: 1924 GGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGENLEKL 1983 Query: 299 EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 358 E + +L +++ + Q P + K + + P ++P Sbjct: 1984 ECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYP---------LRP 2034 Query: 359 QLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP---PEQTHEQPHTQPQVSLLAP 415 Q + P P A P QP P S P P QP + P L P Sbjct: 2035 QTPEPPPPPPPPPPPPLPAAPP--QPASTPAIPASAPPITSPTIAPAQP-SVPLTQLSMP 2091 Query: 416 EQTPVVVHVCGLEMPPDAVEA 436 + P+ + MP + A Sbjct: 2092 MELPIFSPLMMQTMPLQTLPA 2112 Score = 47.4 bits (111), Expect = 6e-05 Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 25/218 (11%) Query: 534 CYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRR 593 C +C+ + + FQ H +H Q+ + H+ + + + + P Sbjct: 986 CKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGN-----PVHL 1040 Query: 594 WCNTCQLY---------------YMGDLIQHRRTQDHK--IAKQSLRPFCTVCNRYFKTP 636 CN C Y + L ++ Q H+ + +S C +CN K Sbjct: 1041 KCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAK 1100 Query: 637 RKFVEHVKSQGHK--DKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEE-EDDEDEE 693 ++HV+S H+ + ++L+ L+K + +DED C D EE ED E Sbjct: 1101 LNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPS 1160 Query: 694 EIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDF 731 E + E + + S + + T SP T+ + F Sbjct: 1161 ETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISF 1198 Score = 43.1 bits (100), Expect = 0.001 Identities = 24/49 (48%), Positives = 29/49 (59%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLP 52 QQ QQ Q Q+ +QQ QQ+QLQQQQ Q+ Q Q + PP AP P Sbjct: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP 3410 Score = 40.4 bits (93), Expect = 0.007 Identities = 22/55 (40%), Positives = 30/55 (54%) Query: 10 LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64 L QQ QQ QQ Q+ +QQQQ +Q Q Q Q++ QQ P + P+ P + P Sbjct: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDP 3414 Score = 39.7 bits (91), Expect = 0.012 Identities = 80/367 (21%), Positives = 137/367 (37%), Gaps = 58/367 (15%) Query: 311 LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--- 367 LQ+ A+ + + +PKL + Q P +Q Q +P+LQQ+ +P+ Sbjct: 2407 LQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQ--PNQTQEKQGQPKPELQQQEQPEQKT 2464 Query: 368 ---KQVQPQVHT-----QAQPSVQPQEHPPAQVSVQPPEQTH-----EQPHTQPQVSLLA 414 +Q PQ+ + Q P P + P Q S P + +H T Q++ L Sbjct: 2465 NTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLP 2524 Query: 415 PEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 474 P+ P C L P E Q+ QN+ + +R+ Sbjct: 2525 PQLIPYQCDQCKLAFP--------SFEHWQEH---QQLHFLSAQNQ----FIHPQFLDRS 2569 Query: 475 REMP-GVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 533 +MP ++ L + L S + +P S + STP +T K+ L+ Sbjct: 2570 LDMPFMLFDPSNPLLASQLLSG--------AIPQIPASSATSPSTPTSTMNTLKRKLEE- 2620 Query: 534 CYICKASCS-SQQEFQDHMSEPQHQQRL------GEIQHMSQACLLSLLPVPRDVLETED 586 KAS S + + EPQ +RL +++ + Q LL P R +L+ Sbjct: 2621 ----KASASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPT-RKMLDHIA 2675 Query: 587 EEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQ 646 E ++ Q+++ + R+ Q + C C FK H++S+ Sbjct: 2676 HEVGLKK--RVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSR 2733 Query: 647 GHKDKAK 653 H +AK Sbjct: 2734 -HWHEAK 2739 Score = 39.3 bits (90), Expect = 0.015 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 7/86 (8%) Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQ--QQQLLQLQQL--LQQSPPQAP---LPMAV 55 S Q Q ++Q Q +LQQQ+ +Q+ QQ+L QL L L Q PPQAP P+ Sbjct: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQ 2496 Query: 56 SRGLPPQQPQQPLLNLQGTNSASLLN 81 S P Q PL L + L N Sbjct: 2497 SSPSPSQLSHLPLKPLHTSTPQQLAN 2522 Score = 38.1 bits (87), Expect = 0.034 Identities = 60/270 (22%), Positives = 99/270 (36%), Gaps = 32/270 (11%) Query: 4 QQQQQQLQQQQQQLQ--------------QLQQQQLQQQQLQQQQLLQLQQLLQQSPPQA 49 Q QQQ QQQQ Q+Q QL QQ QQ++ + + ++ ++ + + Sbjct: 3194 QPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGE- 3252 Query: 50 PLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT 109 PLP +P ++ + T SA L ++ A+ QLQ L T Sbjct: 3253 PLP------VPKKEKGEAPTATAATISAPL---PTMEYAVDPAQLQALQAALTSDPTALL 3303 Query: 110 AGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPM 169 +P G Y PG P L + P A Q+L+G P + Sbjct: 3304 TSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSP-ALSQALMGLSPGSLLQ 3362 Query: 170 NPSQFNLSGRNP-QKQARTSSSTTPNRKTMPVEDKSD----PPEGSEEAAEPRMDTPEDQ 224 Q+ S + Q+Q + +K + K+ PP +P ++P+ + Sbjct: 3363 QYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPE 3422 Query: 225 DLPPCPEDIAK--EKRTPAPEPEPCEASEL 252 + P +++ K PE E A L Sbjct: 3423 EQKNTPREVSPLLPKLPEEPEAESKSADSL 3452 Score = 33.9 bits (76), Expect = 0.64 Identities = 18/50 (36%), Positives = 27/50 (54%) Query: 334 PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ 383 P K+A + + + +Q+Q Q Q QQ+ + Q+Q Q Q QAQ VQ Sbjct: 1704 PSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQ 1753 Score = 33.9 bits (76), Expect = 0.64 Identities = 46/190 (24%), Positives = 71/190 (37%), Gaps = 37/190 (19%) Query: 190 STTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP--------PCPEDIAKEKRTPA 241 S PN+ T + + P +E E + +TP+ Q LP P P A + P Sbjct: 2437 SAQPNQ-TQEKQGQPKPELQQQEQPEQKTNTPQ-QKLPQLVSLPSLPQPPPQAPPPQCPL 2494 Query: 242 PE--PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP-------------- 285 P+ P P + S LP K L +S P QL Q ++ P Sbjct: 2495 PQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFL 2554 Query: 286 ---KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI-------PSTDTQVQPK 335 Q P L +L+ + F P + +Q+ S P+I PST T Sbjct: 2555 SAQNQFIHPQFLDRSLDMPFM-LFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNT 2613 Query: 336 LQKQAQTQTS 345 L+++ + + S Sbjct: 2614 LKRKLEEKAS 2623 Score = 33.5 bits (75), Expect = 0.84 Identities = 15/34 (44%), Positives = 23/34 (67%) Query: 680 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISRE 713 E + EEEE++E+EEE E E+E CK + ++ E Sbjct: 469 EEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502 Score = 32.0 bits (71), Expect = 2.4 Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 6/73 (8%) Query: 313 VQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQP 372 + A + S ++P+ + +Q Q Q QQ+Q Q Q QQ+A+ Q Q Sbjct: 1697 IGANIASPSEPKEANRKKLADMIASRQQQQQQQ------QQQQQQQQQQQQAQTLAQAQA 1750 Query: 373 QVHTQAQPSVQPQ 385 QV Q +Q Q Sbjct: 1751 QVQAHLQQELQQQ 1763 Score = 30.8 bits (68), Expect = 5.4 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 9/54 (16%) Query: 656 KSLEKEIAGQDEDHFITVDAVGCF---------EGDEEEEEDDEDEEEIEVEEE 700 KS E + +G E V CF E +EEEEE++ +EEE E EEE Sbjct: 429 KSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEE 482 Score = 30.4 bits (67), Expect = 7.1 Identities = 14/21 (66%), Positives = 17/21 (80%) Query: 680 EGDEEEEEDDEDEEEIEVEEE 700 E +EEEEE +E+EEE E EEE Sbjct: 464 EEEEEEEEAEEEEEEEEEEEE 484 >gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] Length = 825 Score = 63.9 bits (154), Expect = 6e-10 Identities = 67/296 (22%), Positives = 110/296 (37%), Gaps = 32/296 (10%) Query: 162 PPPVGVPMNPSQFNLSGRNPQKQAR---------TSSSTTPNRKTMPVEDKSDPPEGSEE 212 PP V + Q L P+++AR T + P P+ ++ E S E Sbjct: 414 PPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAE 473 Query: 213 -----AAEPRMD-TPEDQDLPPCPEDIAKEK----RTPAPEPEPCEASELPAKRLRSSEE 262 A EP D TP + P E A+E ++P E E + + L + E Sbjct: 474 IQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEA 533 Query: 263 PTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA------- 315 P ++ P ++ + P + Q+P ++E L P + A Sbjct: 534 PADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAI 593 Query: 316 QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVH 375 Q+ + T+ +VQP ++A + P +VQP +EA + Q P Sbjct: 594 QLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEE 653 Query: 376 TQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 431 A+ P E PA+V P E+ +V L E+TP+ + + PP Sbjct: 654 APAEVQPPPAEEAPAEVQPPPAEE------APAEVQSLPAEETPIEETLAAVHSPP 703 Score = 46.6 bits (109), Expect = 1e-04 Identities = 80/392 (20%), Positives = 144/392 (36%), Gaps = 55/392 (14%) Query: 183 KQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 242 K+ ++ P+ + P + + E + AEPR + P E+ + A Sbjct: 250 KKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAV 309 Query: 243 EPEPCEASELPAKRLRSSEEPTEKEPPG-------QLQVKAQPQARMTVPKQTQTPDLLP 295 + PA+ E P E +PP +L + P + P + ++LP Sbjct: 310 AENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILP 369 Query: 296 EALE----AQVL-----PRFQPRVLQVQ------------AQVQSQTQPRIPSTDTQVQP 334 E ++L P Q ++VQ A+V+ P + T VQP Sbjct: 370 PPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVE---PPTVEETLADVQP 426 Query: 335 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ---------PQ 385 L ++A + + E L L P + E Q + P+ T + S + P Sbjct: 427 LLPEEAPREEARE-LQLSTAMETPAEEAPTEFQSPL-PKETTAEEASAEIQLLAATEPPA 484 Query: 386 EHPPAQVSVQPPEQTH-EQPHTQPQVSL----LAPEQTPVVVHVCGLEMPPDAVEAGGGM 440 + PA+ E+T E+ H + Q L A E + + + +E P D E Sbjct: 485 DETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPAD--ETPAEA 542 Query: 441 EKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG--VWGAGGSLKVTILQSSDSR 498 + L E + + E+Q+ SA G+ + E + G S + +L ++++ Sbjct: 543 QSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEAS 602 Query: 499 AFSTVPLTPVPRPSDSVSS---TPAATSTPSK 527 A P P P++ + P A P++ Sbjct: 603 A-EEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 633 Score = 45.1 bits (105), Expect = 3e-04 Identities = 45/207 (21%), Positives = 73/207 (35%), Gaps = 25/207 (12%) Query: 192 TPNRKTMPVED---KSDPPEGSEEAAEPRM--------------DTPEDQDLPPCPEDIA 234 +P+ K + +E+ + PP G E AE + P + PP E+ Sbjct: 561 SPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPA-EEAP 619 Query: 235 KEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPG--QLQVKAQPQARMTVPKQTQTPD 292 E + P E P E PA+ E P E +PP + + QP P + Q P Sbjct: 620 AEVQPPPAEEAPAEVQPPPAE-----EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPP 674 Query: 293 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 352 E Q LP + + + A V S +P+ + V T + Sbjct: 675 AEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEA 734 Query: 353 QKQVQPQLQQEAEPQKQVQPQVHTQAQ 379 +V P ++ + + V T+ Q Sbjct: 735 SAEVSPPPSEQTPEDEALVENVSTEFQ 761 Score = 42.7 bits (99), Expect = 0.001 Identities = 69/328 (21%), Positives = 126/328 (38%), Gaps = 57/328 (17%) Query: 183 KQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPE---DQDLPPC---------- 229 K +T + ++ VE+ P E S + E ++ PE D ++PP Sbjct: 71 KSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDR 130 Query: 230 -----------------PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL 272 E + KE++T E E S + +S E+ + + G++ Sbjct: 131 SQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKI 190 Query: 273 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 332 P+ + P ++ + + + + V + + + + +P Q Sbjct: 191 FASEHPEFQ---PATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVV--QE 245 Query: 333 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQP--QVHTQAQPSVQPQEHPPA 390 ++K A + P ++QP L +EA + + +P + H Q QPS +E P A Sbjct: 246 GSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPST--EETPDA 303 Query: 391 Q---------VSVQPPEQTHEQPHTQPQVSLLAP--EQTPVVVHVCGLEMPPDAVEAGG- 438 + V VQPP E P + + P E++P V + + +PP A E+ Sbjct: 304 EAATAVAENSVKVQPP-PAEEAPLVEFPAEIQPPSAEESPSVELLAEI-LPPSAEESPSE 361 Query: 439 -GMEKTLPEPVGTQVSME---EIQNESA 462 + LP P S+E EI++ SA Sbjct: 362 EPPAEILPPPAEKSPSVELLGEIRSPSA 389 Score = 34.3 bits (77), Expect = 0.49 Identities = 42/163 (25%), Positives = 59/163 (36%), Gaps = 33/163 (20%) Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAE----PRMDTPEDQDLPPCPEDIAKE 236 P + + P + P E + PP E AE P + P + PP E+ E Sbjct: 613 PPAEEAPAEVQPPPAEEAPAEVQ--PPPAEEAPAEVQPPPAEEAPAEVQPPPA-EEAPAE 669 Query: 237 KRTPAPEPEPCEASELPAKRLRSSEE------------PTEK------EPPGQLQVK--- 275 + P E P E LPA+ E P E+ PP L + Sbjct: 670 VQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEF 729 Query: 276 --AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ-PRVLQVQA 315 + A ++ P QTP+ EAL V FQ P+V + A Sbjct: 730 PIGEASAEVSPPPSEQTPE--DEALVENVSTEFQSPQVAGIPA 770 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 63.5 bits (153), Expect = 8e-10 Identities = 83/365 (22%), Positives = 136/365 (37%), Gaps = 76/365 (20%) Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR---------- 179 P P + PP+ P + P A + PP VP P + + Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKPEA---PPPKVPEAPKEVVPEKKVPVPPPKKPE 10547 Query: 180 -NPQKQARTSSSTTPNRKT---MPVEDKSDPPEGSEE-----------AAEPRMDTPEDQ 224 P K + P +K +P + +S PPE E AA P+ Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPV 10607 Query: 225 DLPPCPEDIAKEKRTPAPEPE-----PCEASELPAKRLRSS------------------E 261 +P P+++ EK+ P P P+ P + E+P + E Sbjct: 10608 KVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFE 10667 Query: 262 EPTE---KEPPGQLQVKAQPQA--RMTVPKQTQTPDLLPEALEAQVLPRFQP-RVLQVQA 315 EP E +EPP ++ + +P A ++TVP + P+ A+ A+ P P +V +V Sbjct: 10668 EPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAK-KPELPPVKVPEVPK 10726 Query: 316 QVQSQTQ-----PRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQV 370 +V + + P+ P P++ K+ V+ +K+V + E P K Sbjct: 10727 EVVPEKKVPLVVPKKPEAPPAKVPEVPKE----------VVPEKKVAVPKKPEVPPAK-- 10774 Query: 371 QPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV-VVHVCGLEM 429 P+V + +P P + PPE E P+ + E+ PV V E+ Sbjct: 10775 VPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEV 10834 Query: 430 PPDAV 434 PP AV Sbjct: 10835 PPPAV 10839 Score = 55.1 bits (131), Expect = 3e-07 Identities = 73/324 (22%), Positives = 132/324 (40%), Gaps = 58/324 (17%) Query: 163 PPVGVPMNPSQFNLSGRNPQKQART--SSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDT 220 PP VP P + P+++ P +P K PE P+ Sbjct: 9974 PPAKVPEVP-------KKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVE 10026 Query: 221 PEDQDLPPCPEDIAKEKRTPAPEPE-----PCEASELPAKRLRSSEEPTE-----KEPPG 270 +P P+ EK+ P P P+ P + E+P K + ++PT + PP Sbjct: 10027 APPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPP 10086 Query: 271 QLQVKAQP-QARMTVPKQTQT---------PDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 320 ++ K +P + +P++ + ++LPE E +VLP + VL + +V + Sbjct: 10087 KVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPE--EEEVLPE-EEEVLPEEEEVLPE 10143 Query: 321 TQPRIPSTDTQVQPKLQ-KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 379 + IP + +V P+ + + + PE VL +V+P++ A P +++ +V + Sbjct: 10144 -EEEIPPEEEEVPPEEEYVPEEEEFVPEEEVL--PEVKPKVPVPA-PVPEIKKKVTEKKV 10199 Query: 380 PSVQPQEHPPAQVSVQP-----------------PEQTHEQPHTQPQVSLLAPEQTPVVV 422 + +E PPA+V P P + E+P +P PE+ P + Sbjct: 10200 VIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIE 10259 Query: 423 HVCGLEMPPDAVEAGGGMEKTLPE 446 V + PP E ++K +PE Sbjct: 10260 EVEEV-APPRVPEV---IKKAVPE 10279 Score = 51.2 bits (121), Expect = 4e-06 Identities = 57/210 (27%), Positives = 85/210 (40%), Gaps = 14/210 (6%) Query: 241 APEPEPCEASELPAKRLRSSEEPTE-KEPPGQLQVKAQPQARMT-VPKQTQTPDLLPEAL 298 A E E E + P K SE+ K+PP ++ + +P A++ VPK+ + + Sbjct: 10427 AEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPE 10486 Query: 299 EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 358 E +V P P VL + V + P P+ + P +A + PE V V P Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKV----PVPP 10542 Query: 359 QLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL-LAPEQ 417 + E P K P+V A P + E P + PPE P+ + AP + Sbjct: 10543 PKKPEVPPTK--VPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPK 10600 Query: 418 TPVVVHVCGLEMPPDAVEAGGGMEKTLPEP 447 P V V E P + V EK +P P Sbjct: 10601 KPEVTPVKVPEAPKEVVP-----EKKVPVP 10625 Score = 51.2 bits (121), Expect = 4e-06 Identities = 72/325 (22%), Positives = 128/325 (39%), Gaps = 41/325 (12%) Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGP-----PPVGVPMNPSQFNLSGRNP-Q 182 +P + A P + P + + + L+ P PP VP P + + Sbjct: 10706 APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765 Query: 183 KQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 242 K+ + P PV ++ E A P + E+ + E+IA E+ P P Sbjct: 10766 KKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVP 10825 Query: 243 -----EPE--PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTP---- 291 EPE P E P K + + P K+P + +P+ + PK P Sbjct: 10826 VAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPP 10885 Query: 292 ------DLLPEALEAQVLPRFQ-PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 344 D+ + + + +P+ + P QV +V+ T ++P + +V+ KL + + + Sbjct: 10886 PAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVE-LTPLKVPGGEKKVR-KLLPERKPEP 10943 Query: 345 SPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV-SVQPPEQTHEQ 403 E ++ K V + +E EP +V+P+ + + P+ PP V V+ P T + Sbjct: 10944 KEEVVL---KSVLRKRPEEEEP--KVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE 10998 Query: 404 ---------PHTQPQVSLLAPEQTP 419 P +P + L APE P Sbjct: 10999 RKIPEPTKVPEIKPAIPLPAPEPKP 11023 Score = 46.2 bits (108), Expect = 1e-04 Identities = 70/300 (23%), Positives = 117/300 (39%), Gaps = 69/300 (23%) Query: 193 PNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQD--LPPCPEDIAKEKRTPAP-EPEPCEA 249 P + P E+K P EE P PE+ +P + K+ P P EPEP + Sbjct: 10812 PEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKV 10871 Query: 250 SELPAKRLRSSEEPTEKEPPGQ------LQVKAQPQARMTVPKQTQTPDLL--------- 294 E P +L+ P PP + Q+KA P+ + VP++ Q P+ + Sbjct: 10872 IEKP--KLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKK--VPEKPQVPEKVELTPLKVPG 10927 Query: 295 -------------PEALEAQVL------------PRFQPRVLQ-VQAQVQSQTQPRIPST 328 PE E VL P+ +P+ L+ V+ + P P Sbjct: 10928 GEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVE 10987 Query: 329 DTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA-EPQKQVQPQVHTQAQPSVQPQEH 387 + +V P + K+ + P + +++P + A EP+ + + +V T P V+P+ Sbjct: 10988 EVEV-PTVTKRERKIPEPTKV----PEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPT 11042 Query: 388 P---PAQVSVQPPEQTHEQPH---TQPQVSLL-APEQTPVVVHV--------CGLEMPPD 432 P P V V + + P +P+ + P++TP + G E PPD Sbjct: 11043 PIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPD 11102 Score = 45.4 bits (106), Expect = 2e-04 Identities = 71/316 (22%), Positives = 125/316 (39%), Gaps = 60/316 (18%) Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK----- 235 P K R +P E++ P E +EE E + E + PP E++ + Sbjct: 10209 PAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPR 10268 Query: 236 -----EKRTP-APEPEPCEASELPAKRLRSSEE-----PTEKE--PPGQLQ--VKAQPQA 280 +K P AP P P + PAK + E P +K+ PP ++ K P+ Sbjct: 10269 VPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEK 10328 Query: 281 RMTVPKQTQTPDLLPE-ALEAQVLPRFQPRVL---QVQAQVQSQTQPRIPSTDT--QVQP 334 ++ VPK+ P LE +V F+ V+ +++ +V IP + +V+ Sbjct: 10329 KVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEE 10388 Query: 335 KLQ-----------KQAQTQTSPEHL---------VLQQKQVQPQLQQEAEPQ-KQVQPQ 373 + K Q + EH V + ++V+ + +A P+ ++ + Sbjct: 10389 YFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEK 10448 Query: 374 VHTQAQP--SVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 431 + +P V P++ PPA+V P + E+ P+ + P + P V +PP Sbjct: 10449 IIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEV-------LPP 10501 Query: 432 DAVEAGGGMEKTLPEP 447 V EK +P P Sbjct: 10502 KEVVP----EKKVPVP 10513 Score = 42.0 bits (97), Expect = 0.002 Identities = 45/262 (17%), Positives = 105/262 (40%), Gaps = 34/262 (12%) Query: 217 RMDTPEDQDLPPCPEDIAKEKRTPAPEP---------------EPCEASELPAKRLRSSE 261 +++ P +P P+ I EK+ PAP P +P ++P K ++ E Sbjct: 9571 KIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEE 9630 Query: 262 EPTEKEPPGQLQVKAQPQARMTVPKQTQTPD---------LLPEALEAQVLPRFQ----P 308 K +Q+ + + + V K+ P +PE ++ P+ + Sbjct: 9631 PLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPA 9690 Query: 309 RVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQK 368 +V + + +V + + I + + QP +++ + L+++ V Q ++E E + Sbjct: 9691 KVTEFRKRVVKEEKVSIEAPKREPQP-IKEVTIMEEKERAYTLEEEAVSVQREEEYEEYE 9749 Query: 369 QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQ--VSLLAPEQTPVVVHVCG 426 + + + +P+ + ++ + + HE+ T+P+ + + + PV Sbjct: 9750 EYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKP-- 9807 Query: 427 LEMPPDAVEAGGGMEKTLPEPV 448 + PP V E+ +P P+ Sbjct: 9808 -KAPPAKVLKKAVPEEKVPVPI 9828 Score = 41.6 bits (96), Expect = 0.003 Identities = 53/265 (20%), Positives = 101/265 (38%), Gaps = 23/265 (8%) Query: 198 MPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE----PCEASELP 253 +P+ K +PP + P+ PE++ P P+ KE P PE P ++P Sbjct: 9303 VPIPKKVEPP-APKVPEVPKKPVPEEKKPVPVPK---KEPAAPPKVPEVPKKPVPEEKIP 9358 Query: 254 AKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV------LPRFQ 307 + E P K P Q V + + + ++ P +PE + +V +PR + Sbjct: 9359 VPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKE 9418 Query: 308 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA---QTQTSPEHLVLQQKQVQPQLQQEA 364 V +V + + +P V + K+A + + S + +V +++ V + A Sbjct: 9419 EEV-PPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFA 9477 Query: 365 EPQKQVQPQVHTQAQPS-VQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVV- 422 PQ+ + A+ +E +SV E+ E+ + + E VV Sbjct: 9478 VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVE 9537 Query: 423 ---HVCGLEMPPDAVEAGGGMEKTL 444 H+ + + E EK + Sbjct: 9538 EKLHIISKRVEAEPAEVTERQEKKI 9562 Score = 40.8 bits (94), Expect = 0.005 Identities = 61/271 (22%), Positives = 116/271 (42%), Gaps = 42/271 (15%) Query: 192 TPNRKTMPVEDKSDPPEGSEEAAEP----RMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 247 T K +PV+ + P ++ A P + PE++ P P+ K P P P Sbjct: 9787 TEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPK-----KLKPPPPKVPE 9841 Query: 248 EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTV-PKQTQTPDLLPEALEAQVLPRF 306 E ++ +++R S EKE QV +P A++ + PK+ + +P +PR Sbjct: 9842 EPKKVFEEKIRISITKREKE-----QV-TEPAAKVPMKPKRVVAEEKVP-------VPR- 9887 Query: 307 QPRVLQVQAQVQSQTQPRIPSTDTQVQPK-LQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 365 +V V R+P +++P+ + + + T E ++++++ ++E Sbjct: 9888 ----KEVAPPV------RVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFI 9937 Query: 366 PQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVC 425 +++V P + + P V + P + V P++ P P+V E+ PV++ Sbjct: 9938 TEEEVVPVIPVKV-PEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIP-- 9994 Query: 426 GLEMPPDA----VEAGGGMEKTLPEPVGTQV 452 E PP A V E+ +P PV +V Sbjct: 9995 KKEKPPPAKVPEVPKKPVPEEKVPVPVPKKV 10025 Score = 38.1 bits (87), Expect = 0.034 Identities = 42/224 (18%), Positives = 92/224 (41%), Gaps = 20/224 (8%) Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240 P+ +AR+++ K + +E K PP+ + R+ P PE+I P Sbjct: 8911 PRGEARSTAELYLTTKEIKLELK--PPD----IPDSRVPIPTMPIRAVPPEEIPPVVAPP 8964 Query: 241 APEPEPC-EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALE 299 P P E + P KR+ +++ +K+ + + R + K+ P L Sbjct: 8965 IPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTL----- 9019 Query: 300 AQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 359 +P P ++ V ++ + I + ++QK+ + + V ++K+V + Sbjct: 9020 ---IPAKAPEIIDVSSKAEEVKIMTITR-----KKEVQKEKEAVYEKKQAVHKEKRVFIE 9071 Query: 360 LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQ 403 +E + +V+P QP + + ++ V+ ++ HE+ Sbjct: 9072 SFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEE 9115 Score = 36.2 bits (82), Expect = 0.13 Identities = 66/340 (19%), Positives = 124/340 (36%), Gaps = 57/340 (16%) Query: 208 EGSEEAAEPRMDTPEDQDLPPCPEDI---AKEKRTPAPEPE---PCEASELPAKRLRSSE 261 EG +E E + +++++ +++ + E++ PA PE P + + E Sbjct: 9131 EGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIE 9190 Query: 262 EPTEKEPPGQLQVKAQPQ-ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 320 + + + ++QV P+ ++ VP++ + E +E +V P V + + + Sbjct: 9191 KTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKV-----PAVHTKKMVISEE 9245 Query: 321 TQPRIPSTDTQVQ---PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQ 377 T+ +V P++QK+ T+ V K+V+P + P+K +V Sbjct: 9246 KMFFASHTEEEVSVTVPEVQKEIVTEEKIH--VAISKRVEPPPKVPELPEKPAPEEVAPV 9303 Query: 378 AQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAG 437 P P + P ++P P+ AP + P E+P V Sbjct: 9304 PIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVP--------EVPKKPVP-- 9353 Query: 438 GGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDS 497 E+ +P PV + + A V E + G K+TI+ + Sbjct: 9354 ---EEKIPVPVA--------KKKEAPPAKVPEVQK---------GVVTEEKITIVTQREE 9393 Query: 498 RAFSTVP----------LTPVPRPSDSVSSTPAATSTPSK 527 VP PVPR + V P + P K Sbjct: 9394 SPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKK 9433 Score = 35.8 bits (81), Expect = 0.17 Identities = 34/191 (17%), Positives = 77/191 (40%), Gaps = 7/191 (3%) Query: 215 EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV 274 EPR + +L ++I E + P +P + + E P PP L + Sbjct: 8910 EPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLL 8969 Query: 275 KAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 334 P+ + PK+ + + +V+ + P+ + + ++ + P T + Sbjct: 8970 PT-PEEKKPPPKRIEVTKKAVKKDAKKVVAK--PKEMTPREEIVKKPPP----PTTLIPA 9022 Query: 335 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSV 394 K + + E + + + ++Q+E E + + VH + + ++ E P ++ V Sbjct: 9023 KAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEV 9082 Query: 395 QPPEQTHEQPH 405 +P + EQP+ Sbjct: 9083 EPYTEPFEQPY 9093 Score = 35.8 bits (81), Expect = 0.17 Identities = 57/279 (20%), Positives = 105/279 (37%), Gaps = 29/279 (10%) Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 188 SP A P + P+ P ++ P+ + PPP VP P + P + + + Sbjct: 9394 SPPPAVPEI--PKKKVPEERKPVPRKEEEV---PPPPKVPALP-------KKPVPEEKVA 9441 Query: 189 SSTTPNRKTMPVE---DKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE 245 +K P K E AE ++ Q + +++ E+ E E Sbjct: 9442 VPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEE 9501 Query: 246 PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPR 305 E + R EE E E + +V +P+ V ++ EA A+V R Sbjct: 9502 --EGVSISVYREEEREEEEEAEVT-EYEVMEEPE-EYVVEEKLHIISKRVEAEPAEVTER 9557 Query: 306 FQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 365 + +++ +P+IP+ + P +A + PE V + ++ Sbjct: 9558 QEKKIV---------LKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKV 9608 Query: 366 PQKQVQPQVHTQAQPSVQPQEHP-PAQVSVQPPEQTHEQ 403 P++ +P + P V E P PA+V+ + + T E+ Sbjct: 9609 PEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEE 9647 Score = 34.3 bits (77), Expect = 0.49 Identities = 49/266 (18%), Positives = 104/266 (39%), Gaps = 20/266 (7%) Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 189 P + P PP+ P + + L P P P P + ++ + Q +A Sbjct: 10853 PVIKKPEAPPPKEPEPE------KVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKA-IPK 10905 Query: 190 STTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKE--KRTPAPEPEPC 247 P + +P + + P + + R PE + P E + K ++ P E Sbjct: 10906 KKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPK-EEVVLKSVLRKRPEEEEPKV 10964 Query: 248 EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ 307 E +L + + EP +P +++V + +P+ T+ P++ P A LP + Sbjct: 10965 EPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKP----AIPLPAPE 11020 Query: 308 PRVLQVQAQVQSQTQPRIPSTDTQVQ-----PKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 362 P+ + +A+V++ P + T + P + K+A+ + E + ++ ++ Sbjct: 11021 PKP-KPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKK 11079 Query: 363 EAEPQKQVQPQVHTQAQPSVQPQEHP 388 P + + ++ + P E P Sbjct: 11080 TPSPIEAERRKLRPGSGGEKPPDEAP 11105 Score = 32.3 bits (72), Expect = 1.9 Identities = 55/290 (18%), Positives = 101/290 (34%), Gaps = 30/290 (10%) Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240 P K T K + K + P + EP+ PE++ L K KR Sbjct: 9633 PAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLK------LKPKREE 9686 Query: 241 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 300 P + E + K + S E ++EP QP +T+ ++ + L E EA Sbjct: 9687 EPPAKVTEFRKRVVKEEKVSIEAPKREP--------QPIKEVTIMEEKERAYTLEE--EA 9736 Query: 301 QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL 360 + R + + + + Q + +++ + E + + ++ P Sbjct: 9737 VSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVK 9796 Query: 361 QQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ---PPEQTHEQP----HTQPQVSLL 413 EP + P+E P + + PP + E+P + ++S+ Sbjct: 9797 PVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISIT 9856 Query: 414 APEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEP---VGTQVSMEEIQNE 460 E+ V + M P V A E+ +P P V V + E+ E Sbjct: 9857 KREKEQVTEPAAKVPMKPKRVVA----EEKVPVPRKEVAPPVRVPEVPKE 9902 >gi|148277037 AP2 associated kinase 1 [Homo sapiens] Length = 961 Score = 63.2 bits (152), Expect = 1e-09 Identities = 77/299 (25%), Positives = 109/299 (36%), Gaps = 45/299 (15%) Query: 189 SSTTPNRKTMPVEDKSDPPEGSEEAAEPRM------DTPEDQDLPPCPEDIAKEKRTPAP 242 +S +KT P +DP +E + PR P LP P +++ T P Sbjct: 339 ASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQP 398 Query: 243 EPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL--EA 300 P+ +S P L S +P + PP Q + Q + P QTP + L +A Sbjct: 399 PPQAAGSSNQPGL-LASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQA 457 Query: 301 QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK----LQKQAQTQT------------ 344 Q P+ Q ++ Q Q Q Q P Q QP Q+QAQTQ Sbjct: 458 QATPQHQQQLFLKQQQQQQQPPP------AQQQPAGTFYQQQQAQTQQFQAVHPATQQPA 511 Query: 345 ----------SPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQP--QEHPPAQV 392 + ++Q Q Q QQ+ + Q+Q+ +H Q + Q Q+ P Sbjct: 512 IAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAA 571 Query: 393 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQ 451 QP Q P QP + Q PV PP AV+ T P TQ Sbjct: 572 GQQPQPQPAAAP--QPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKTQ 628 Score = 55.8 bits (133), Expect = 2e-07 Identities = 56/207 (27%), Positives = 82/207 (39%), Gaps = 21/207 (10%) Query: 229 CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV--KAQPQARMTVPK 286 CP + PA PEP +ASE AK+ + T+ P + + + +P+A T P Sbjct: 319 CPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQP- 377 Query: 287 QTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL---------- 336 P +LP ++ + PR + V S QP + ++ Q +P+ Sbjct: 378 ---NPGILP--IQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQ 432 Query: 337 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQP--QEHPPAQVSV 394 KQ Q +P+ Q Q P Q +A PQ Q Q + Q Q P Q+ P Sbjct: 433 AKQPQAPPTPQQTPSTQAQGLP-AQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQ 491 Query: 395 QPPEQTHEQPHTQPQVSLLAPEQTPVV 421 Q QT + P A Q PVV Sbjct: 492 QQQAQTQQFQAVHPATQQPAIAQFPVV 518 Score = 50.8 bits (120), Expect = 5e-06 Identities = 31/67 (46%), Positives = 34/67 (50%), Gaps = 6/67 (8%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQA------PLPMAVSR 57 QQ Q QQQQQ QQ QQQQ L QQQL+ Q LQQ P A P P A + Sbjct: 525 QQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQ 584 Query: 58 GLPPQQP 64 P Q+P Sbjct: 585 PAPAQEP 591 Score = 39.7 bits (91), Expect = 0.012 Identities = 68/236 (28%), Positives = 87/236 (36%), Gaps = 36/236 (15%) Query: 5 QQQQQLQQQQQQLQQLQQQQ------LQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58 QQQ L+QQQQQ Q QQ QQQQ Q QQ + QQ P A P+ G Sbjct: 464 QQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQ-PAIAQFPVVSQGG 522 Query: 59 LPP-------QQPQQPLLNLQGTNSASLLNGS--MLQRALLL--------QQLQGLDQFA 101 QQ QQ Q A+ L+ M Q+A L QQ Q A Sbjct: 523 SQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAA 582 Query: 102 MPPATYDTAGLTMPTATLGNLRGY-GMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLL 160 PA + P ++ A G SLTPP ++P Q+ + + Sbjct: 583 PQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPP--SSPKTQRAGHRRILSDVT 640 Query: 161 GPPPVGVPMNPSQFNL------SGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGS 210 GVP + S L + N K A T+ S +P V +P EGS Sbjct: 641 HSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNV---YNPSEGS 693 Score = 30.0 bits (66), Expect = 9.3 Identities = 24/69 (34%), Positives = 27/69 (39%), Gaps = 5/69 (7%) Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQ-----QLQQQQLLQLQQLLQQSPPQAPLPMAVSR 57 +Q +Q Q QQ Q Q L Q Q QQQ L+ QQ QQ PP P Sbjct: 431 TQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFY 490 Query: 58 GLPPQQPQQ 66 Q QQ Sbjct: 491 QQQQAQTQQ 499 >gi|197276594 RNA binding motif protein 20 [Homo sapiens] Length = 1227 Score = 62.8 bits (151), Expect = 1e-09 Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%) Query: 634 KTPRKFVEHVKSQGH-KDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 692 + P FV+ K++G +D A E LE++ + E + C E E + Sbjct: 1057 RQPSPFVDDCKTRGTPEDGACEGSPLEEKASPPIETD---LQNQACQEVLTPENSRYVEM 1113 Query: 693 EEIEVEEELCKQVRSRD-ISREEWKGSETYSP-NTAYGVDFLVPVMGYICRICHKFYHSN 750 + +EV +V + +S W+ + +S + GV+F+VP G+ C++C FY S Sbjct: 1114 KSLEVRSPEYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSE 1173 Query: 751 SGAQLSHCKSLGHFENLQKY 770 A++SHC+S H+ NLQKY Sbjct: 1174 ETAKMSHCRSAVHYRNLQKY 1193 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 62.8 bits (151), Expect = 1e-09 Identities = 67/306 (21%), Positives = 117/306 (38%), Gaps = 45/306 (14%) Query: 203 KSDPPEGSE--EAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSS 260 +SD EG E EA E + P D + + PE E EA E + S Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPES 1887 Query: 261 EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 320 E+ E ++Q +++ K+ Q EALE + + Sbjct: 1888 EDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETE-----------------GE 1930 Query: 321 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQ--- 377 +P + Q + ++A+ QT PE V++ ++ + + Q E+E + ++ +V TQ Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAE 1990 Query: 378 --AQPSVQPQEHPPAQ----------------VSVQPPEQTHEQPHTQPQVSLLAPEQTP 419 AQP + E P A+ V QP + E + + + P Sbjct: 1991 GEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQP 2050 Query: 420 VVVHVCGLEMPPDAVEAGGGMEKTLPE--PVGTQVSMEEIQNES---ACGLDVGECENRA 474 V E +A EA G +++ E P V +E + E+ + G++ E E A Sbjct: 2051 ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEA 2110 Query: 475 REMPGV 480 ++ G+ Sbjct: 2111 QKAEGI 2116 Score = 52.8 bits (125), Expect = 1e-06 Identities = 59/245 (24%), Positives = 98/245 (40%), Gaps = 18/245 (7%) Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240 P+ + + + VE ++ EG + ++ PE ++ E +E Sbjct: 2018 PESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGE 2077 Query: 241 A-PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALE 299 A PE E +A E + SE E G+ Q KA+ + Q EA E Sbjct: 2078 AHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQ-KAEGIEAPETEGEAQPESEGIEAPE 2136 Query: 300 AQVLPRFQPRVLQVQAQ-VQSQTQPRIPSTDTQ-----VQPKLQ----KQAQTQTSPEHL 349 A+ QP V+AQ + + QP + Q QP+L+ +A+ + PE Sbjct: 2137 AE--GEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESE 2194 Query: 350 VLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQ--THEQPHTQ 407 ++ + + + Q E E + P+ +AQP + E P A+ QP + T + Sbjct: 2195 GIEAPEAEGEAQPELEGVEA--PEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGS 2252 Query: 408 PQVSL 412 PQVSL Sbjct: 2253 PQVSL 2257 Score = 48.5 bits (114), Expect = 3e-05 Identities = 59/244 (24%), Positives = 99/244 (40%), Gaps = 24/244 (9%) Query: 199 PVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCPEDI-AKEKRTPA-PEPEPCEASELP-- 253 P D + PE EEA E + E + + P ED+ A+E A PE E EA E Sbjct: 2050 PESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGE 2109 Query: 254 ---AKRLRSSEEPTEKEPPGQ------LQVKAQPQARMTVPKQTQTPDLLPEA--LEAQV 302 A+ + + E E +P + + +AQP++ V Q + PE+ +EAQ Sbjct: 2110 AQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE-GVEAQDAEGEAQPESEGIEAQE 2168 Query: 303 LPR-FQPRVLQVQA-QVQSQTQPR-----IPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355 QP + V+A + + + QP P + + QP+L+ + E + Sbjct: 2169 AEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGV 2228 Query: 356 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 415 P+ + EA+P+ + + Q + P V + + S ++P P P Sbjct: 2229 ETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTP 2288 Query: 416 EQTP 419 Q P Sbjct: 2289 HQRP 2292 Score = 45.1 bits (105), Expect = 3e-04 Identities = 87/437 (19%), Positives = 157/437 (35%), Gaps = 64/437 (14%) Query: 182 QKQARTSSSTTPNRK--TMPVEDKSDPPEGSEEAAEPRMDTPE--DQDLPPCPEDIAKEK 237 + Q + TP + P + ++ PE +EA +P ++ E + + PE E Sbjct: 1882 EAQPESEDVETPEAEWEVQPESEGAEAPEAEKEA-QPETESVEALETEGEDEPESEGAEA 1940 Query: 238 RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEA 297 + + E P + S+E E+ P V+A + V Q + PE+ Sbjct: 1941 QEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEA---LEVEVETQEAEGEAQPES 1997 Query: 298 LEAQVLPRFQPRVLQVQAQVQSQT-----QPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 352 + + P + + + + + Q ++ QP+ + Q ++ + PE ++ Sbjct: 1998 EDVEA-PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVE 2056 Query: 353 QKQVQPQLQQEAEPQKQVQPQVHT------------QAQPSVQPQEHPPAQVSVQPPEQT 400 + + + Q+ ++ + + H +AQP + E P A+ Q E Sbjct: 2057 APEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGI 2116 Query: 401 HEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA--VEAGGGMEKTLPEPVG--TQVSMEE 456 E P T+ + PE + E P++ VEA + PE G Q + EE Sbjct: 2117 -EAPETEGEAQ---PESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEE 2172 Query: 457 IQNESACGLDVGECENRAR-EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSV 515 Q E G++ E E A+ E G+ ++ A + P + Sbjct: 2173 AQPELE-GVEAPEAEGEAQPESEGIEA----------PEAEGEAQPELEGVEAPEAEEEA 2221 Query: 516 SSTPAATSTPSKQALQFFCYICKASCSSQQEFQ-DHMSEPQHQQRLGEIQHMSQACLLSL 574 P TP + +A S+ E Q + PQ G+ + S+ S Sbjct: 2222 QPEPEGVETPEAEG--------EAQPESEGETQGEKKGSPQVSLGDGQSEEASE----SS 2269 Query: 575 LPVPRDVLETEDEEPPP 591 PVP D PPP Sbjct: 2270 SPVPED-----RPTPPP 2281 Score = 30.0 bits (66), Expect = 9.3 Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 14/89 (15%) Query: 640 VEHVKSQGHKD------KAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEE 693 VE ++++G + +A+E + +E GQ + +++ E +EE + + ED E Sbjct: 1922 VEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ---EAEEEAQPESEDVE 1978 Query: 694 EIEVEEELCK-----QVRSRDISREEWKG 717 +EVE E + Q S D+ E +G Sbjct: 1979 ALEVEVETQEAEGEAQPESEDVEAPEAEG 2007 >gi|221139761 zinc finger protein 853 [Homo sapiens] Length = 659 Score = 62.4 bits (150), Expect = 2e-09 Identities = 70/251 (27%), Positives = 111/251 (44%), Gaps = 26/251 (10%) Query: 178 GRNPQKQARTSSSTTPNRKTMPVEDKSDP-------PEGSEEAAEPRMDTPEDQDLPPCP 230 G P + S + + P E S P P G+ E AE P ++L Sbjct: 36 GPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETR--PGQREL---- 89 Query: 231 EDIAKEKRTPAPEPEPC-EASELPAKRLRSSEEPTEKEPPGQLQV-KAQPQARMTVPKQT 288 + + ++ P P+ +P E + P L ++P + GQ Q+ + Q + +V Q Sbjct: 90 -QLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQD---GQQQLSQLQQEKHQSVHHQE 145 Query: 289 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS-PE 347 P+L + Q+ QP+ +Q Q ++Q Q Q ++ + Q Q LQ+Q Q Q E Sbjct: 146 LKPELQLMHQQQQL----QPQQVQEQQRLQQQ-QEQLQTQQAQEQQVLQQQEQLQQQVQE 200 Query: 348 HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEH-PPAQVSVQPPEQTHEQPHT 406 +LQQ+Q Q Q QQ + Q+Q+Q Q Q Q +Q Q+ Q Q +Q +Q Sbjct: 201 QQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQA 260 Query: 407 QPQVSLLAPEQ 417 Q Q LL +Q Sbjct: 261 QLQQQLLEQQQ 271 Score = 59.3 bits (142), Expect = 1e-08 Identities = 50/107 (46%), Positives = 59/107 (55%), Gaps = 19/107 (17%) Query: 5 QQQQQLQQQ-------QQQLQQLQQQQL--QQQQLQQQQLLQLQQLLQQSPPQAPLPMAV 55 QQQ+QLQQQ QQQ +QLQQQQL QQ+QLQQQQ Q Q+ LQQ Q L + Sbjct: 189 QQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQ---QQQLLLLQ 245 Query: 56 SRGLPPQQPQQPLLNLQGTNSASLL---NGSMLQRALLLQQLQGLDQ 99 +G Q QQ LL Q L + LQ+ LLLQQ + L Q Sbjct: 246 QQG----QLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288 Score = 57.4 bits (137), Expect = 5e-08 Identities = 40/96 (41%), Positives = 47/96 (48%) Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 M QQQ Q Q Q+QQ Q QQ+QLQ QQ Q+QQ+LQ Q+ LQQ + L L Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212 Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG 96 QQ Q LQ Q+ LLL Q QG Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQG 248 Score = 57.0 bits (136), Expect = 7e-08 Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 5/185 (2%) Query: 230 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL--QVKAQPQARMTVPKQ 287 P+ + +++R + + + L+ E+ ++ QL Q + Q Q + + +Q Sbjct: 161 PQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ 220 Query: 288 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 347 Q + + Q+ + Q +LQ Q Q+Q Q + Q+Q +L +Q Q Q + Sbjct: 221 EQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL---LQQQQAQLQQQLLEQQQAQLQQQ 277 Query: 348 HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 407 L+ QQ+Q+Q Q QQ+ Q+Q Q Q P ++P+E ++ + P + EQ Q Sbjct: 278 LLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQ 337 Query: 408 PQVSL 412 + L Sbjct: 338 QRQEL 342 Score = 57.0 bits (136), Expect = 7e-08 Identities = 35/66 (53%), Positives = 40/66 (60%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63 QQQQ+QLQQQQQ L QQ QLQQQ LQQQQ QQLL+Q Q + + + QQ Sbjct: 229 QQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288 Query: 64 PQQPLL 69 QQ L Sbjct: 289 QQQQQL 294 Score = 55.5 bits (132), Expect = 2e-07 Identities = 67/261 (25%), Positives = 112/261 (42%), Gaps = 15/261 (5%) Query: 171 PSQFNLSGRNPQKQARTSSS-----TTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQ- 224 P + N S + P A +S T P ++ + ++ PE ++ ++ P+ Sbjct: 57 PQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHL 116 Query: 225 DLPPCPEDIAKEKRTPAPEPEPCEASELPAK-RLRSSEEPTEKEPPG-QLQVKAQPQARM 282 +L P+ +++ + + + K L+ + + +P Q Q + Q Q Sbjct: 117 ELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQ 176 Query: 283 TVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQT 342 +Q Q +L + + Q + Q + Q Q Q+Q Q Q Q Q Q+Q Q Sbjct: 177 LQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ-QLLQQQEQLQQQQFQQQQEQL 235 Query: 343 QTSPEHLVLQQK-QVQPQL--QQEAEPQKQV--QPQVHTQAQPSVQPQEHPPAQVSVQPP 397 Q + L+LQQ+ Q+Q QL QQ+A+ Q+Q+ Q Q Q Q +Q QE Q Q Sbjct: 236 QQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLL 295 Query: 398 EQTHEQ-PHTQPQVSLLAPEQ 417 +Q EQ Q Q L PE+ Sbjct: 296 QQQQEQLQQQQLQPPPLEPEE 316 Score = 54.7 bits (130), Expect = 4e-07 Identities = 47/102 (46%), Positives = 57/102 (55%), Gaps = 9/102 (8%) Query: 5 QQQQQLQQQQQQLQ--QLQQQQL--QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSR--G 58 Q+QQ+LQQQQ+QLQ Q Q+QQ+ QQ+QLQQQ +Q QQLLQQ Q + + Sbjct: 165 QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQ--VQEQQLLQQQQEQLQQQQLLQQQEQ 222 Query: 59 LPPQQPQQPLLNLQGTNSASLL-NGSMLQRALLLQQLQGLDQ 99 L QQ QQ LQ LL LQ+ LL QQ L Q Sbjct: 223 LQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQ 264 Score = 51.6 bits (122), Expect = 3e-06 Identities = 39/69 (56%), Positives = 42/69 (60%), Gaps = 5/69 (7%) Query: 5 QQQQQLQQQ--QQQLQQLQQQQLQQQ--QLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60 QQQ QLQQQ QQQ QLQQQ L+QQ QLQQQ LLQ Q+ LQQ Q L + L Sbjct: 245 QQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQ-LQ 303 Query: 61 PQQPQQPLL 69 QQ Q P L Sbjct: 304 QQQLQPPPL 312 Score = 49.7 bits (117), Expect = 1e-05 Identities = 38/79 (48%), Positives = 45/79 (56%), Gaps = 10/79 (12%) Query: 3 SQQQQQQLQQQQQQLQQ--LQQQQLQQQQLQQQQLLQLQQ-LLQQSPPQAPLPMAVSRGL 59 +Q QQQ L+QQQ QLQQ L QQQ Q QQ QQQQLLQ QQ LQQ Q P L Sbjct: 260 AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPP-------PL 312 Query: 60 PPQQPQQPLLNLQGTNSAS 78 P++ ++ L L + S Sbjct: 313 EPEEEEEVELELMPVDLGS 331 Score = 43.9 bits (102), Expect = 6e-04 Identities = 47/255 (18%), Positives = 104/255 (40%), Gaps = 11/255 (4%) Query: 169 MNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPP 228 + P Q R Q+Q + + ++ + +++ ++ + + + + Q L Sbjct: 159 LQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQ 218 Query: 229 CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA--QPQARMTVPK 286 E + +++ E + L ++ ++ ++ QLQ + Q QA++ Sbjct: 219 QQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQL 278 Query: 287 QTQTPDLLPEALEAQVLPRFQPRVLQVQAQV-------QSQTQPRIPSTDTQVQPKLQKQ 339 Q + L + + Q+L + Q ++ Q Q Q + + + + D + +L++Q Sbjct: 279 LLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQ 338 Query: 340 AQTQTSPEHLVLQQ--KQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPP 397 Q + L QQ +Q+Q +LQ+E + +Q Q Q + E P ++ Q Sbjct: 339 RQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQ 398 Query: 398 EQTHEQPHTQPQVSL 412 E E QP++ L Sbjct: 399 EVQLELTPVQPELQL 413 Score = 42.7 bits (99), Expect = 0.001 Identities = 91/420 (21%), Positives = 155/420 (36%), Gaps = 48/420 (11%) Query: 12 QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNL 71 Q++ QLQQL+QQ QQQ Q +QL Q P P + P Q QQ L L Sbjct: 86 QRELQLQQLEQQPEPQQQPQHEQL------------QQPQPHLELQQQPQQDGQQQLSQL 133 Query: 72 QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPG 131 Q S+ + + L+ Q Q L P + L L + Sbjct: 134 QQEKHQSVHHQELKPELQLMHQQQQL----QPQQVQEQQRLQQQQEQLQTQQ--AQEQQV 187 Query: 132 LAAPSLTPPQLATPN-LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSS 190 L Q+ LQQ Q +Q LL + QF Q+Q + Sbjct: 188 LQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE---QLQQQQFQQQQEQLQQQQQLLLL 244 Query: 191 TTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEAS 250 + + + + ++ E + + Q L E + ++++ + + Sbjct: 245 QQQGQLQQQLLQQQQ-AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQ---QQE 300 Query: 251 ELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRV 310 +L ++L+ P E E +++++ P + + + + E Q L R Q Sbjct: 301 QLQQQQLQ--PPPLEPEEEEEVELELMP---VDLGSEQELEQQRQELERQQELER-QQEQ 354 Query: 311 LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQV 370 Q+Q ++Q + Q + Q Q Q++ Q + +P L QQ++VQ +L V Sbjct: 355 RQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLEL-------TPV 407 Query: 371 QPQVHTQAQPSV----QPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCG 426 QP++ + P+ PA V V PP Q ++ +L P VV + G Sbjct: 408 QPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQ-----ELMVLPAVAAPAVVAIPG 462 Score = 42.4 bits (98), Expect = 0.002 Identities = 42/111 (37%), Positives = 49/111 (44%), Gaps = 20/111 (18%) Query: 4 QQQQQQLQQQQQQLQQLQQQQL-------------QQQQLQQQQLLQLQQLLQQSPPQAP 50 QQ QQ QQQ QLQQ + Q + QQQQLQ QQ+ Q QQ LQQ Q Sbjct: 120 QQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQV-QEQQRLQQQQEQLQ 178 Query: 51 LPMAVSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGLDQ 99 A + + QQ Q Q LL LQ+ LLQQ + L Q Sbjct: 179 TQQAQEQQVLQQQEQLQ----QQVQEQQLLQQQQEQLQQQQLLQQQEQLQQ 225 Score = 42.4 bits (98), Expect = 0.002 Identities = 31/74 (41%), Positives = 45/74 (60%), Gaps = 6/74 (8%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQ---QQQLQQ--QQLLQLQQLLQQSPPQAPLPMAVSRG 58 +QQ+Q+L++QQ+ +Q +Q+QLQ Q++LQQ QQL Q QQ L+Q Q L V G Sbjct: 336 EQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLEL-TPVELG 394 Query: 59 LPPQQPQQPLLNLQ 72 Q+ Q L +Q Sbjct: 395 AQQQEVQLELTPVQ 408 Score = 31.6 bits (70), Expect = 3.2 Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 47/175 (26%) Query: 4 QQQQQQLQQQQQQLQQLQQQ----------------------------------QLQQQQ 29 QQQQQ LQQQQ+QLQQ Q Q + QQ+ Sbjct: 289 QQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQEL 348 Query: 30 LQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRAL 89 +QQ+ QLQ LQ+ Q + + L QQ Q +Q + L + L Sbjct: 349 ERQQEQRQLQLKLQEELQQ------LEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQL 402 Query: 90 LLQQLQGLDQFAMPPATYDTAGLT--MPTATLGNLRGYG-----MASPGLAAPSL 137 L +Q Q + PA P A + GY M P +AAP++ Sbjct: 403 ELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQELMVLPAVAAPAV 457 >gi|33286444 mastermind-like 2 [Homo sapiens] Length = 1156 Score = 61.6 bits (148), Expect = 3e-09 Identities = 45/98 (45%), Positives = 50/98 (51%), Gaps = 6/98 (6%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQ-----QQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58 QQQQQQ QQQQQQ QQ QQQQ Q QQQ QQQ + QQ QQ Q + Sbjct: 599 QQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQ 658 Query: 59 LPPQQPQQPLLNLQGTNSASLLNGSM-LQRALLLQQLQ 95 QQ Q Q S LL + LQ+ LLLQQ+Q Sbjct: 659 QQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696 Score = 59.3 bits (142), Expect = 1e-08 Identities = 106/498 (21%), Positives = 178/498 (35%), Gaps = 102/498 (20%) Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 188 SPGL PQL P+ F A P VP + +Q PQ + S Sbjct: 369 SPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQ-------PQTGSGAS 421 Query: 189 SSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCE 248 + ++ + ++ A + + Q P + + + P P P Sbjct: 422 RALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQ-----PTNWSALPSSAGPSPGPFG 476 Query: 249 ASELPAKRL-------RSSEEPTEKEPPGQLQV------KAQPQAR---MTVPKQTQTPD 292 ++P+ +SS P GQ +V KA P A+ + V Q Q P Sbjct: 477 QEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQ-QKPQ 535 Query: 293 LLPEALEAQVLPRFQPRV---------------LQVQAQVQSQTQPRIPSTDTQVQPKLQ 337 L + P +PR Q+ + + SQ +P + Q Q + Q Sbjct: 536 DLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQ 595 Query: 338 KQAQTQTSPEHLVLQQKQVQPQLQQE----AEPQKQVQPQVHTQAQPSVQPQEHPPAQVS 393 +Q Q Q + QQ+Q Q Q QQ+ A+ Q+Q Q + Q Q Q Q+ Q Sbjct: 596 QQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQ 655 Query: 394 VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVS 453 Q +Q +QP +QP SL P Q P++ P P+ ++ Sbjct: 656 QQQQQQQQQQPSSQPAQSL--PSQ-PLL---------------------RSPLPLQQKLL 691 Query: 454 MEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSD 513 ++++QN+ G+ + + ++ V G P P P+ Sbjct: 692 LQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTG--------------------PSPSPNP 731 Query: 514 SVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLS 573 + + S+Q+L + + +Q Q + E Q QQ L + Q ++ A ++ Sbjct: 732 CSNPNTGSGYMNSQQSL-----LNQQLMGKKQTLQRQIME-QKQQLLLQQQMLADAEKIA 785 Query: 574 LLPVPRDVLETEDEEPPP 591 P+D + PPP Sbjct: 786 ----PQDQINRHLSRPPP 799 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/66 (48%), Positives = 38/66 (57%), Gaps = 1/66 (1%) Query: 6 QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65 QQQQ QQQQQQ QQ QQQQ QQQQ QQ Q L Q ++PLP+ + L Q Sbjct: 639 QQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ-QKLLLQQMQN 697 Query: 66 QPLLNL 71 QP+ + Sbjct: 698 QPIAGM 703 Score = 45.8 bits (107), Expect = 2e-04 Identities = 79/331 (23%), Positives = 110/331 (33%), Gaps = 18/331 (5%) Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62 SQ + L QQQ QQ QQQQ QQQQ QQQQ Q QQ QQ S Q Sbjct: 577 SQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQS-------SISAQQQ 629 Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAG-LTMPTATLGN 121 Q QQ ++ Q Q+ QQ Q + P + + L P Sbjct: 630 QQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQK 689 Query: 122 LRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP 181 L M + +A Q + Q T S P P P S + S ++ Sbjct: 690 LLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPS-PSPNPCSNPNTGSGYMNSQQSL 748 Query: 182 QKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQ---DLPPCPEDIAKEKR 238 Q T R+ M E K + A+ P+DQ L P D K++R Sbjct: 749 LNQQLMGKKQTLQRQIM--EQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDY-KDQR 805 Query: 239 TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL 298 +P + + + P + + ++ T+ P L Sbjct: 806 RNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQ 865 Query: 299 EAQV---LPRFQPRVLQVQAQVQSQTQPRIP 326 + LP QP V + + TQ R P Sbjct: 866 NMGMYGNLPCNQPNTYSVTSGMNQLTQQRNP 896 Score = 35.4 bits (80), Expect = 0.22 Identities = 29/97 (29%), Positives = 35/97 (36%) Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62 +QQ L Q + QQ QQQQ QQQQ Q QQ QQ Q + Q Sbjct: 568 NQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQ 627 Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQ 99 Q QQ ++ Q+ QQ Q Q Sbjct: 628 QQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQ 664 Score = 33.1 bits (74), Expect = 1.1 Identities = 75/411 (18%), Positives = 149/411 (36%), Gaps = 56/411 (13%) Query: 6 QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65 Q+ QQ +Q+ +QQ + QQ QQQ L S +P P + P Q Sbjct: 428 QEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQ 487 Query: 66 Q-------PLLNLQGTNSASLLNGSMLQRALLLQQLQGLD-QFAMPPATYDTAGLTMPTA 117 Q P+ + G + S + + + +A Q LD P + + P Sbjct: 488 QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNP-- 545 Query: 118 TLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLS 177 P++ P Q T L F Q + P + PS + + Sbjct: 546 ----------------HPAMEPRQGNTKPLFHFNSDQANQQM--PSVLPSQNKPSLLHYT 587 Query: 178 GRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 237 + Q+Q + ++ + + + + + + + I+ ++ Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQ-------SSISAQQ 640 Query: 238 RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEA 297 + + + + + ++ + ++P+ + P Q + +QP R +P Q + LL + Sbjct: 641 QQQQQQQQQQQQQQQQQQQQQQQQQPSSQ--PAQ-SLPSQPLLRSPLPLQQK---LLLQQ 694 Query: 298 LEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ 357 ++ Q + +V +Q Q Q Q + +T P + T ++ QQ + Sbjct: 695 MQNQPIAGMGYQV----SQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLN 750 Query: 358 PQ-------LQQEAEPQKQ---VQPQVHTQAQPSVQPQEHPPAQVSVQPPE 398 Q LQ++ QKQ +Q Q+ A+ + PQ+ +S PP+ Sbjct: 751 QQLMGKKQTLQRQIMEQKQQLLLQQQMLADAE-KIAPQDQINRHLSRPPPD 800 Score = 33.1 bits (74), Expect = 1.1 Identities = 75/332 (22%), Positives = 126/332 (37%), Gaps = 41/332 (12%) Query: 2 FSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLL---QQSPPQAPLPMAVSRG 58 + QQ L QQ +Q Q+Q+ + Q+QQLL QQ+L ++ PQ + +SR Sbjct: 741 YMNSQQSLLNQQLMGKKQTLQRQIME---QKQQLLLQQQMLADAEKIAPQDQINRHLSRP 797 Query: 59 LPPQQPQ-------QPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAG 111 P + Q QP G +S LN + + ++ ++ T Sbjct: 798 PPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRM 857 Query: 112 LTMPTATLGNLRGYG---MASPGLAAPSLTPPQLATP-NLQQFFPQATRQSLLGPPPVGV 167 ++ TA + N+ YG P + + QL N +Q + PP +G Sbjct: 858 PSLSTA-VQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGP 916 Query: 168 PMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP 227 N + + + + T + +MP + S+ S A P + E Sbjct: 917 SNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTA-PNWASQEGTSK- 974 Query: 228 PCPEDIAKEKRTPAPE--PEPCEASELPAKRLR---SSEEPTEK--EPPGQL----QVKA 276 +E T A P A+ P + L+ S++ +++ PP QL Q++ Sbjct: 975 ------QQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRP 1028 Query: 277 QPQARMTVPKQTQTP----DLLPEALEAQVLP 304 Q T+ QT P +L P L Q+LP Sbjct: 1029 MNQMSQTLNGQTMGPLRGLNLRPNQLSTQILP 1060 >gi|15812226 transcriptional regulating factor 1 [Homo sapiens] Length = 1200 Score = 61.6 bits (148), Expect = 3e-09 Identities = 113/462 (24%), Positives = 170/462 (36%), Gaps = 99/462 (21%) Query: 5 QQQQQLQQQQQQLQQLQQQQL---QQQQLQQQQLLQLQQLL---QQSPPQAPLPMAVSRG 58 Q Q Q Q +QQ+QQ Q QQQQ QQ + +Q++ QQ P P P Sbjct: 249 QPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQP------ 302 Query: 59 LPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAM---PPATY-------D 108 PPQQ Q L LQ S+ Q ++Q LQ Q M PP+ + Sbjct: 303 -PPQQQQPQQLQLQ-QRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP 360 Query: 109 TAGLTMPTATLGNLRGYGMASPGLAAPSLTP----------PQLATPNLQQFFPQATRQS 158 T+ LG++ Y P P P Q L+ + Q+ Sbjct: 361 EQAHTVQLIPLGSMSQYYYQEP--QQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQA 418 Query: 159 L------LGPPPVGVP-------------------MNPSQFNLSGRNPQKQARTSSSTTP 193 + LGPP G+ ++PS +L+ PQ Q + S+ P Sbjct: 419 MLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWP 478 Query: 194 NRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELP 253 M + D P E + +P+ E D AK K T + + E LP Sbjct: 479 Q---MHLPDGRAQPGSPESSGQPKGAFGEQFD--------AKNKLTCSICLK--EFKNLP 525 Query: 254 A--KRLRS----SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP---EALEAQVLP 304 A +RS P K+ G+ + QPQ + P P LP E+L V+P Sbjct: 526 ALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMP 585 Query: 305 RFQP-RVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ-QKQVQPQLQQ 362 P ++L + Q T + + + +P A + + E VL+ ++ QP + + Sbjct: 586 VSVPVKLLPPKPSSQGFTNSTVAAPSARDKP-----ASSMSDDEMPVLEIPRKHQPSVPK 640 Query: 363 EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQP 404 EP K VQ + + H P + + PP + P Sbjct: 641 AEEPLKTVQEK---------KKFRHRPEPLFIPPPPSYNPNP 673 Score = 60.8 bits (146), Expect = 5e-09 Identities = 55/221 (24%), Positives = 96/221 (43%), Gaps = 11/221 (4%) Query: 194 NRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELP 253 N + +S +G+ ++A ++ + + + PP P ++ ++ P +P P L Sbjct: 160 NNMAQVLHTQSAVMDGAPDSALRQLLSQKPME-PPAPAIPSRYQQVPQ-QPHPGFTGGLS 217 Query: 254 AKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP--KQTQTPDLLPEALEAQVLPRFQPRVL 311 L+ + PT+ Q QP A++ V + Q P +L + ++ ++ P Sbjct: 218 KPALQVGQHPTQGHLYYDYQ---QPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQ 274 Query: 312 QVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQ 371 Q QA Q + I + Q++P + Q P+ L LQQ+Q Q+ Q +PQ +Q Sbjct: 275 QQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQ 334 Query: 372 PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL 412 H Q Q Q PP+ P + T EQ HT + L Sbjct: 335 ---HLQEQQQQQMHLQPPS-YHRDPHQYTPEQAHTVQLIPL 371 >gi|4507379 TATA box binding protein [Homo sapiens] Length = 339 Score = 60.5 bits (145), Expect = 6e-09 Identities = 34/62 (54%), Positives = 38/62 (61%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63 QQQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ + + Q ++G Q Sbjct: 59 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQA 118 Query: 64 PQ 65 PQ Sbjct: 119 PQ 120 Score = 56.6 bits (135), Expect = 9e-08 Identities = 33/60 (55%), Positives = 36/60 (60%) Query: 6 QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65 ++QQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ QA AV + Q Q Sbjct: 53 EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112 Score = 50.8 bits (120), Expect = 5e-06 Identities = 30/60 (50%), Positives = 35/60 (58%) Query: 7 QQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQ 66 ++Q +QQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ Q + A + QQ Q Sbjct: 53 EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112 Score = 48.1 bits (113), Expect = 3e-05 Identities = 31/66 (46%), Positives = 36/66 (54%), Gaps = 2/66 (3%) Query: 10 LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLL 69 L++QQ+Q QQ QQQQ QQQQ QQQQ Q QQ QQ Q AV+ Q Q Sbjct: 52 LEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQA- 110 Query: 70 NLQGTN 75 QGT+ Sbjct: 111 -TQGTS 115 Score = 45.1 bits (105), Expect = 3e-04 Identities = 27/63 (42%), Positives = 31/63 (49%) Query: 11 QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLN 70 +QQ+QQ QQ QQQQ QQQQ QQQQ Q QQ QQ Q + + QQ Sbjct: 54 EQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQG 113 Query: 71 LQG 73 G Sbjct: 114 TSG 116 Score = 38.9 bits (89), Expect = 0.020 Identities = 27/66 (40%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLL-QQSPPQAPLPMAVSRGLPPQ 62 QQQQQQ QQQQQ + QQ QQ Q Q QL Q+ APLP P Sbjct: 84 QQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPM 143 Query: 63 QPQQPL 68 P P+ Sbjct: 144 TPMTPI 149 Score = 38.5 bits (88), Expect = 0.026 Identities = 22/44 (50%), Positives = 25/44 (56%) Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQ 48 Q L ++Q +Q QQQQ QQQQ QQQQ Q QQ QQ Q Sbjct: 44 QNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 87 Score = 37.4 bits (85), Expect = 0.058 Identities = 24/84 (28%), Positives = 38/84 (45%) Query: 337 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP 396 Q++ Q Q + QQ+Q Q Q QQ+ + Q+Q Q Q QA + Q+ Q + Sbjct: 55 QQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGT 114 Query: 397 PEQTHEQPHTQPQVSLLAPEQTPV 420 Q + H+Q + P TP+ Sbjct: 115 SGQAPQLFHSQTLTTAPLPGTTPL 138 Score = 37.0 bits (84), Expect = 0.076 Identities = 28/112 (25%), Positives = 42/112 (37%) Query: 295 PEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQK 354 P+ +P F P + Q + + Q + Q+Q Q Q + QQ+ Sbjct: 17 PQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQ 76 Query: 355 QVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHT 406 Q Q Q QQ+ + Q+Q Q Q A + S Q P+ H Q T Sbjct: 77 QQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLT 128 Score = 34.3 bits (77), Expect = 0.49 Identities = 31/124 (25%), Positives = 43/124 (34%) Query: 308 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ 367 P Q A Q P IP + Q + L + ++Q + Q QQ+ + Q Sbjct: 8 PPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQ 67 Query: 368 KQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL 427 +Q Q Q Q Q Q Q+ Q Q Q T Q + Q P + H L Sbjct: 68 QQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTL 127 Query: 428 EMPP 431 P Sbjct: 128 TTAP 131 Score = 31.2 bits (69), Expect = 4.2 Identities = 33/117 (28%), Positives = 44/117 (37%), Gaps = 7/117 (5%) Query: 269 PGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPST 328 P Q A PQ MT +P ++P P L + + Q Q Q + Sbjct: 8 PPYAQGLASPQGAMTPGIPIFSP-MMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQ--QQ 64 Query: 329 DTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQ 385 Q Q + Q+Q Q Q + QQ+Q Q Q QQ+A VQ QA Q Sbjct: 65 QQQQQQQQQQQQQQQQQQQ----QQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQ 117 Score = 30.0 bits (66), Expect = 9.3 Identities = 42/171 (24%), Positives = 60/171 (35%), Gaps = 20/171 (11%) Query: 12 QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNL 71 Q Q L + QQ+Q QQQQ Q QQ QQ Q QQ QQ Sbjct: 41 QPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQ------------QQQQQQQQQQQ 88 Query: 72 QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPG 131 Q + + +Q++ Q QG P + + T T L G P Sbjct: 89 QQQQQQQAVAAAAVQQSTSQQATQGTS--GQAPQLFHS-----QTLTTAPLPGTTPLYPS 141 Query: 132 LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 182 P +TP ATP + Q+++ +G ++ L RN + Sbjct: 142 PMTP-MTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAE 191 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 60.5 bits (145), Expect = 6e-09 Identities = 103/401 (25%), Positives = 131/401 (32%), Gaps = 94/401 (23%) Query: 45 SPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPP 104 +PP +P P+ LP P LQ + S ++ S L L + LQ L A Sbjct: 450 TPPDSP-PLQAPLSLPASPP------LQTSLSPAV---SPLSSPLTIHPLQALSSLASHS 499 Query: 105 ATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164 + L MP P SL PP L TP P L PPP Sbjct: 500 PQAPLSSLIMP--------------PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545 Query: 165 VGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQ 224 + Q ++ TTP+ +T P P +A + TP Sbjct: 546 L------------------QTASAPLTTPHLETPPC-----PAPCPLQAPPSPLTTPP-- 580 Query: 225 DLPPCPEDIAKEKRTPAPEPEPCEASE----LPAKRLRSSEEPTEKEPPG----QLQVKA 276 P P IA TP P+ P AS LP+ L P + PP LQ Sbjct: 581 --PETPSSIA----TPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP 634 Query: 277 QPQARMTV-PKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 335 P A + P T +P P AL +L P P VQ Sbjct: 635 SPPASPPLSPLATPSPQA-PNALAVHLLQA-----------------PFSPPPSPPVQAP 676 Query: 336 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVS-- 393 A SP Q P L A P QV P A P + P PP Q Sbjct: 677 FSPPASPPVSPS--ATPPSQAPPSL---AAPPLQVPPS--PPASPPMSPSATPPPQAPPP 729 Query: 394 -VQPPEQTHEQPHTQPQVSLLA--PEQTPVVVHVCGLEMPP 431 PP Q P P +S A P + P ++ L++PP Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770 Score = 60.1 bits (144), Expect = 8e-09 Identities = 103/412 (25%), Positives = 133/412 (32%), Gaps = 56/412 (13%) Query: 45 SPPQAPLPMAV-SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRA---LLLQQLQGLDQF 100 SPP P A S PP Q L + L LQ L L LQ Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418 Query: 101 AMPPATYDTAGLTM-PTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL 159 P + LTM P T +L SP + P+ TPP +P LQ SL Sbjct: 419 GSPTLQATHSFLTMSPRQTQASL-----TSP--SRPASTPPD--SPPLQ------APLSL 463 Query: 160 LGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPP-EGSEEAAEPRM 218 PP+ ++P+ LS + SS + P+ PP E A P + Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523 Query: 219 DTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 278 TP P E++ P+ P P + + P P P ++A P Sbjct: 524 QTPPASLTTPPLENL------PSLAPPPLQTASAPLTTPHLETPPC----PAPCPLQAPP 573 Query: 279 QARMTVPKQTQT-----PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQ 333 T P +T + P P AL + L L A Q P + Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL------AL 627 Query: 334 PKLQKQAQTQTSPEHLVLQQKQVQP---------QLQQEAEPQKQVQPQVHTQAQPSVQP 384 P LQ SP L Q Q P VQ A P V P Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687 Query: 385 QEHPPAQVS---VQPPEQTHEQPHTQPQVSLLA--PEQTPVVVHVCGLEMPP 431 PP+Q PP Q P P +S A P Q P + L++PP Sbjct: 688 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739 Score = 53.5 bits (127), Expect = 8e-07 Identities = 88/368 (23%), Positives = 111/368 (30%), Gaps = 79/368 (21%) Query: 127 MASPGLAAPSLTPPQLAT------PNLQQFFPQATRQSLLGP----PPVGVPMNPSQFNL 176 + SP PS PP + T P+LQ P SL P PP + ++ Q Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416 Query: 177 SGRNPQKQARTSSSTTPNRKTM-----PVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPE 231 S +P QA S T R+T P S PP+ P + P LP P Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD------SPPLQAP--LSLPASPP 468 Query: 232 DIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEK-----EPPGQLQVK------AQPQA 280 +P P L A +S P PP + Q P A Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA 528 Query: 281 RMTVPKQTQTPDLLPEALEAQVLPRFQPRV----------LQVQAQVQSQTQPRIPST-- 328 +T P P L P L+ P P + LQ + P PS+ Sbjct: 529 SLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA 588 Query: 329 -------DTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL---QQEAEPQKQVQPQVHTQA 378 P LQ SP L Q P L +A P P + A Sbjct: 589 TPPPQAPPALASPPLQGLPSPPLSP--LATPPPQAPPXLALPPLQAPPSPPASPPLSPLA 646 Query: 379 QPSVQ---------------PQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVH 423 PS Q P PP Q PP P P P Q P + Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP------PSQAPPSLA 700 Query: 424 VCGLEMPP 431 L++PP Sbjct: 701 APPLQVPP 708 Score = 43.1 bits (100), Expect = 0.001 Identities = 74/302 (24%), Positives = 102/302 (33%), Gaps = 40/302 (13%) Query: 162 PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTP 221 P PV P S G QK R S+ T R ++ P+ S +A R DT Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA-----TEAPKRSALSAGARRDTS 165 Query: 222 EDQDLPPCPEDIAKEKRT---------PAPEPEPCEASELPAKRLRSSEE--PTEKEPPG 270 P P +A+ R PAP P +E P K + S+ E TE P Sbjct: 166 GPTPGTPSPA-MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 224 Query: 271 QLQVKA-----QPQARMTVPKQTQTPDLLPEALEAQVLPR-----FQPRVLQVQAQVQSQ 320 + + A +P +R T A+ PR QP+ +QA Q Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284 Query: 321 -TQPR---------IPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQV 370 T PR + S+ +A+ P++ P A P Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLA 344 Query: 371 QPQVHTQAQPSVQPQEHPPAQVSVQ-PPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEM 429 P A PS+Q PPA Q PP T P + + P Q P + L+ Sbjct: 345 PPS--PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402 Query: 430 PP 431 PP Sbjct: 403 PP 404 Score = 37.4 bits (85), Expect = 0.058 Identities = 55/227 (24%), Positives = 74/227 (32%), Gaps = 64/227 (28%) Query: 46 PPQAPLPMAVSR-GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPP 104 PPQAP P+A +PP P P ++ T + L +PP Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV------------PPLLAAPPLQVPP 770 Query: 105 ATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164 + P A+L SP P PP LATP LQ L PP Sbjct: 771 S---------PPASLP-------MSPLAKPPPQAPPALATPPLQ----------ALPSPP 804 Query: 165 VGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQ 224 P + F+ S P S TP PP+ A P + P Sbjct: 805 ASFP-GQAPFSPSASLPM-----SPLATP------------PPQAPPVLAAPLLQVPPS- 845 Query: 225 DLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQ 271 PP + +R P P P+ + + RL + P PP + Sbjct: 846 --PPASPTLQAPRRPPTPGPD----TSVSGPRLTLALAPGPPPPPSR 886 Score = 33.9 bits (76), Expect = 0.64 Identities = 87/322 (27%), Positives = 107/322 (33%), Gaps = 88/322 (27%) Query: 42 LQQSP-PQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQF 100 LQ P P A LPM+ PPQ P AL LQ L Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPP----------------------ALATPPLQALPS- 802 Query: 101 AMPPATYDTAGLTMPTATLGN---LRGYGMASPGLAAPSL----TPPQLAT--------- 144 PPA++ P+A+L A P LAAP L +PP T Sbjct: 803 --PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860 Query: 145 --PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSST-TPNRKTMPVE 201 P+ P+ T GPPP P LSG P +SS+T TP + Sbjct: 861 PGPDTSVSGPRLTLALAPGPPP--PPSRSPSSTLSG--PDLAGHSSSATSTPEE----LR 912 Query: 202 DKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP---------EPEPCEASEL 252 PEG AA P P D +L C A R PAP P P + Sbjct: 913 GYDSGPEGG-AAASP----PPDAELAACHP--AAWSRGPAPPLAFRGAPGAPLPWPPATG 965 Query: 253 PAK-----RLRSSEEPTEKEP-PGQLQVKAQP-------------QARMTVPKQTQTPDL 293 P + +E P P PG L P A PKQ + +L Sbjct: 966 PGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGEL 1025 Query: 294 LPEALEAQVLPRFQPRVLQVQA 315 AL+A V+ R L + A Sbjct: 1026 PLGALQASVVQHLLSRTLLLAA 1047 >gi|110347429 mediator complex subunit 12 [Homo sapiens] Length = 2177 Score = 60.5 bits (145), Expect = 6e-09 Identities = 48/108 (44%), Positives = 51/108 (47%), Gaps = 20/108 (18%) Query: 4 QQQQQQLQQQQQQLQQLQQQQL--------------QQQQLQQQQLLQLQQLLQQSPPQA 49 QQQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ Q Sbjct: 2056 QQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQ 2115 Query: 50 PLPMAVSRGLPPQ-QPQ-QPLLNLQGTNSASLLNGSMLQRALLLQQLQ 95 + PPQ QPQ QP QG Q A L++QLQ Sbjct: 2116 HQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQ----QQQQTAALVRQLQ 2159 Score = 56.6 bits (135), Expect = 9e-08 Identities = 57/206 (27%), Positives = 81/206 (39%), Gaps = 13/206 (6%) Query: 224 QDLPPCPEDIAKEKRT-PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 282 Q P + ++ T PA P S P + S PT +P LQ + Sbjct: 1942 QGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQ 2001 Query: 283 TVPKQ----TQTPDLLPEALE-AQVLPRFQPRVLQ-VQAQVQSQT----QPRIPSTDTQV 332 P T T + L+ ++ P Q VQA V+S Q + Q Sbjct: 2002 QAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQ 2061 Query: 333 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 392 Q + Q+Q Q Q ++ + QQ+Q Q QQ+ + Q+Q Q Q Q Q Q Q+H Q Sbjct: 2062 QQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQ 2121 Query: 393 SVQPPEQTHEQPHTQPQVSLLAPEQT 418 P Q QP +QPQ +QT Sbjct: 2122 QQAAPPQP--QPQSQPQFQRQGLQQT 2145 Score = 50.8 bits (120), Expect = 5e-06 Identities = 43/144 (29%), Positives = 62/144 (43%), Gaps = 11/144 (7%) Query: 278 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV----- 332 P + V ++ +LPE + Q + Q + Q Q Q Q Q Q I Q Sbjct: 2032 PMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQ 2091 Query: 333 -QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA---EPQKQVQPQVHTQAQPSVQPQEHP 388 Q + Q+Q Q Q + QQ+Q Q Q QQ+A +PQ Q QPQ Q Q Q+ Sbjct: 2092 QQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQT 2151 Query: 389 PAQVSVQPPEQTHEQPHTQPQVSL 412 A V + ++ QP QP ++ Sbjct: 2152 AALVRQLQQQLSNTQP--QPSTNI 2173 Score = 47.8 bits (112), Expect = 4e-05 Identities = 35/74 (47%), Positives = 38/74 (51%), Gaps = 5/74 (6%) Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ----QLLQQSPPQAPLPMAVSRGL 59 QQQQQQ QQQQQQ QQ QQQQ Q Q Q Q Q Q QQ A L + + L Sbjct: 2103 QQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQL 2162 Query: 60 PPQQPQQPLLNLQG 73 QP QP N+ G Sbjct: 2163 SNTQP-QPSTNIFG 2175 Score = 43.9 bits (102), Expect = 6e-04 Identities = 27/57 (47%), Positives = 30/57 (52%) Query: 10 LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQ 66 L +QQQQ QQ QQQQ QQQQ QQQQ Q + QQ Q + QQ QQ Sbjct: 2048 LPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQ 2104 Score = 42.7 bits (99), Expect = 0.001 Identities = 40/137 (29%), Positives = 60/137 (43%), Gaps = 20/137 (14%) Query: 257 LRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQ 316 +RS+ E++ Q Q + Q Q + +Q Q + + + Q+L + Q + Q Q Q Sbjct: 2042 VRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQ 2101 Query: 317 VQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQV-- 374 Q Q Q + Q Q + Q+Q Q Q +P Q Q QPQ Q++ Q Q Q Q Sbjct: 2102 QQQQQQQQ-----QQQQQQHQQQQQQQAAPPQ---PQPQSQPQFQRQGLQQTQQQQQTAA 2153 Query: 375 ----------HTQAQPS 381 +TQ QPS Sbjct: 2154 LVRQLQQQLSNTQPQPS 2170 Score = 32.7 bits (73), Expect = 1.4 Identities = 62/243 (25%), Positives = 91/243 (37%), Gaps = 58/243 (23%) Query: 215 EPRMDTPEDQDLPPCPEDIAKEKRTPAP---------EPEPCEASELPAKRLRSSEEPTE 265 EP PED++ PP P + EK+ P P P E + K + S+ T+ Sbjct: 1740 EPLPLPPEDEE-PPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATK 1798 Query: 266 KEPPGQLQVKAQPQARMTVPKQTQTPDLL----PEAL--------------EAQVLPRFQ 307 E G ++ P +TVP PDLL P ++ + Q LP Sbjct: 1799 TEDYGMGPGRSGPYG-VTVP-----PDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGG 1852 Query: 308 PRV-------LQVQAQVQSQTQPRI-PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 359 PRV L +Q T P + P+T T V +T +Q QP Sbjct: 1853 PRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSV--------YRQQQPA 1904 Query: 360 LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ-----PPEQTHE--QPHTQPQVSL 412 + Q ++Q+Q Q SV Q P + +Q P +H Q HT P ++ Sbjct: 1905 VPQGQRLRQQLQQSQGMLGQSSVH-QMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTM 1963 Query: 413 LAP 415 + P Sbjct: 1964 VPP 1966 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.127 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 40,310,703 Number of Sequences: 37866 Number of extensions: 2417780 Number of successful extensions: 45286 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 541 Number of HSP's successfully gapped in prelim test: 1031 Number of HSP's that attempted gapping in prelim test: 19704 Number of HSP's gapped (non-prelim): 13079 length of query: 837 length of database: 18,247,518 effective HSP length: 111 effective length of query: 726 effective length of database: 14,044,392 effective search space: 10196228592 effective search space used: 10196228592 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.