Guide to the Human Genome
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Search of human proteins with 196115153

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3
[Homo sapiens]
         (837 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ...  1698   0.0  
gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ...  1692   0.0  
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ...  1662   0.0  
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [...  1662   0.0  
gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ...  1630   0.0  
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       88   3e-17
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    83   9e-16
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              78   4e-14
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       77   9e-14
gi|56549696 E1A binding protein p400 [Homo sapiens]                    71   4e-12
gi|38788274 bromodomain PHD finger transcription factor isoform ...    69   2e-11
gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens]               67   7e-11
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    66   1e-10
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo...    66   1e-10
gi|38788260 bromodomain PHD finger transcription factor isoform ...    66   2e-10
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   65   2e-10
gi|22538413 forkhead box P2 isoform III [Homo sapiens]                 65   2e-10
gi|149999352 forkhead box P2 isoform II [Homo sapiens]                 65   2e-10
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]          64   4e-10
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       64   6e-10
gi|110349719 titin isoform N2-A [Homo sapiens]                         64   8e-10
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    63   1e-09
gi|197276594 RNA binding motif protein 20 [Homo sapiens]               63   1e-09
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              63   1e-09
gi|221139761 zinc finger protein 853 [Homo sapiens]                    62   2e-09
gi|33286444 mastermind-like 2 [Homo sapiens]                           62   3e-09
gi|15812226 transcriptional regulating factor 1 [Homo sapiens]         62   3e-09
gi|4507379 TATA box binding protein [Homo sapiens]                     60   6e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   6e-09
gi|110347429 mediator complex subunit 12 [Homo sapiens]                60   6e-09

>gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3
           [Homo sapiens]
          Length = 837

 Score = 1698 bits (4398), Expect = 0.0
 Identities = 837/837 (100%), Positives = 837/837 (100%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240
           PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP
Sbjct: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240

Query: 241 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 300
           APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA
Sbjct: 241 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 300

Query: 301 QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL 360
           QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL
Sbjct: 301 QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL 360

Query: 361 QQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 420
           QQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV
Sbjct: 361 QQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 420

Query: 421 VVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGV 480
           VVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGV
Sbjct: 421 VVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGV 480

Query: 481 WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS 540
           WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS
Sbjct: 481 WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS 540

Query: 541 CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQL 600
           CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQL
Sbjct: 541 CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQL 600

Query: 601 YYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEK 660
           YYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEK
Sbjct: 601 YYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEK 660

Query: 661 EIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSET 720
           EIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSET
Sbjct: 661 EIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSET 720

Query: 721 YSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTT 780
           YSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTT
Sbjct: 721 YSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTT 780

Query: 781 RPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 837
           RPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 781 RPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 837


>gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2
           [Homo sapiens]
          Length = 842

 Score = 1692 bits (4382), Expect = 0.0
 Identities = 837/842 (99%), Positives = 837/842 (99%), Gaps = 5/842 (0%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235
           PQKQARTSSSTTPNRK     TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240

Query: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300

Query: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355
           EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360

Query: 356 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 415
           VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP
Sbjct: 361 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 420

Query: 416 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 475
           EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR
Sbjct: 421 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 480

Query: 476 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 535
           EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY
Sbjct: 481 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 540

Query: 536 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 595
           ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC
Sbjct: 541 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 600

Query: 596 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 655
           NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL
Sbjct: 601 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 660

Query: 656 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 715
           KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW
Sbjct: 661 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 720

Query: 716 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 775
           KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN
Sbjct: 721 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 780

Query: 776 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 835
           PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL
Sbjct: 781 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 840

Query: 836 KT 837
           KT
Sbjct: 841 KT 842


>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1
           [Homo sapiens]
          Length = 898

 Score = 1662 bits (4304), Expect = 0.0
 Identities = 837/898 (93%), Positives = 837/898 (93%), Gaps = 61/898 (6%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235
           PQKQARTSSSTTPNRK     TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240

Query: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300

Query: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355
           EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360

Query: 356 VQPQLQQEAEPQ------------------------------------------------ 367
           VQPQLQQEAEPQ                                                
Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420

Query: 368 ----KQVQ----PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 419
               KQVQ    PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480

Query: 420 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 479
           VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540

Query: 480 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 539
           VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600

Query: 540 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 599
           SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660

Query: 600 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 659
           LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720

Query: 660 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 719
           KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780

Query: 720 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 779
           TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840

Query: 780 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 837
           TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898


>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
           [Homo sapiens]
          Length = 898

 Score = 1662 bits (4304), Expect = 0.0
 Identities = 837/898 (93%), Positives = 837/898 (93%), Gaps = 61/898 (6%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235
           PQKQARTSSSTTPNRK     TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240

Query: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300

Query: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355
           EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360

Query: 356 VQPQLQQEAEPQ------------------------------------------------ 367
           VQPQLQQEAEPQ                                                
Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420

Query: 368 ----KQVQ----PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 419
               KQVQ    PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480

Query: 420 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 479
           VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540

Query: 480 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 539
           VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600

Query: 540 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 599
           SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660

Query: 600 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 659
           LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720

Query: 660 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 719
           KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780

Query: 720 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 779
           TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840

Query: 780 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 837
           TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898


>gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4
           [Homo sapiens]
          Length = 818

 Score = 1630 bits (4221), Expect = 0.0
 Identities = 813/842 (96%), Positives = 813/842 (96%), Gaps = 29/842 (3%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG                        
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96

Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 97  NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156

Query: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235
           PQKQARTSSSTTPNRK     TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216

Query: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276

Query: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355
           EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 277 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336

Query: 356 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 415
           VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP
Sbjct: 337 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 396

Query: 416 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 475
           EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR
Sbjct: 397 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 456

Query: 476 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 535
           EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY
Sbjct: 457 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 516

Query: 536 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 595
           ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC
Sbjct: 517 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 576

Query: 596 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 655
           NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL
Sbjct: 577 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 636

Query: 656 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 715
           KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW
Sbjct: 637 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 696

Query: 716 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 775
           KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN
Sbjct: 697 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 756

Query: 776 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 835
           PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL
Sbjct: 757 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 816

Query: 836 KT 837
           KT
Sbjct: 817 KT 818


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 88/319 (27%), Positives = 129/319 (40%), Gaps = 46/319 (14%)

Query: 5   QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54
           Q QQQ+QQQQQQLQ++       QQQQ QQQQ QQQQ LQ Q  +QQ P   PQ P   A
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285

Query: 55  VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAM 102
           + + L          PP QPQQP +     N  S L      + L+   Q L G   +  
Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342

Query: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL--- 159
           PP  +  A + +    +       +     A  +    Q+  P +Q       +  +   
Sbjct: 343 PPLKFVRAPMVVQQPPVQP----QVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIR 398

Query: 160 -LGPPPVGVPMNPSQFNLSGRNPQKQARTS-----SSTTPNRKTMPVEDKSDPPEGSEEA 213
              PP   V   PS     GR P  Q   S     SS +P ++    +    PP+ S + 
Sbjct: 399 ARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQP 458

Query: 214 AEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQ 273
            +P      +    P P   +     P+P P+P + S + A+  ++   P+    PG L 
Sbjct: 459 GQPSSQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS----PGPLN 510

Query: 274 VKAQPQARMTVPKQTQTPD 292
               P + M+    +Q  +
Sbjct: 511 TPVNPSSVMSPAGSSQAEE 529



 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 57/195 (29%), Positives = 90/195 (46%), Gaps = 11/195 (5%)

Query: 241 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 300
           AP      ++  P  +L+  +   +++   Q Q + Q QA +   +Q Q      +A ++
Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194

Query: 301 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 359
            +  +FQ  V Q Q  Q Q Q Q  +     Q Q ++Q+Q Q       L LQQ+Q Q Q
Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254

Query: 360 LQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 418
            QQ+ + Q  Q QP +    QP +Q  + PP+Q   Q  +Q H   H QP      P+Q 
Sbjct: 255 QQQQQQQQALQAQPPIQ---QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQP 308

Query: 419 PVVVHVCGLEMPPDA 433
           PV  +    ++PP +
Sbjct: 309 PVAQNQPS-QLPPQS 322



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 67/267 (25%), Positives = 99/267 (37%), Gaps = 25/267 (9%)

Query: 152 PQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSE 211
           P    QSL G P  G     +   +  R P +      S        P+     PP G+ 
Sbjct: 81  PMNALQSLTGGPAAGA----AGIGMPPRGPGQSLGGMGSL--GAMGQPMSLSGQPPPGTS 134

Query: 212 EAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQ 271
             A   M           P+   + ++    + +  +  +   +     ++  +++   Q
Sbjct: 135 GMAPHSMAVVSTAT----PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQ 190

Query: 272 LQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQ 331
            Q  A  Q    V +Q Q   L  +  + Q L +      Q Q Q+Q Q Q        Q
Sbjct: 191 AQQSAMQQQFQAVVQQQQ--QLQQQQQQQQHLIKLHH---QNQQQIQQQQQQLQRIAQLQ 245

Query: 332 VQPKLQKQAQTQTSPEHLVLQQKQVQ-PQLQQEAEPQKQVQPQV-----HTQ-AQPSVQP 384
           +Q + Q+Q Q Q   +  +  Q  +Q P +QQ   P  Q  PQ      HTQ  QP  QP
Sbjct: 246 LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQP 305

Query: 385 QEHPPAQVSVQPPEQTHEQPHTQPQVS 411
           Q+ P AQ     P Q   Q  TQP VS
Sbjct: 306 QQPPVAQ---NQPSQLPPQSQTQPLVS 329



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 55/205 (26%), Positives = 78/205 (38%), Gaps = 27/205 (13%)

Query: 271 QLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ-PRVLQVQAQVQSQTQPRIPSTD 329
           QLQ + Q Q  +          +  +  + Q + + Q  +  Q Q Q Q Q Q  + +  
Sbjct: 209 QLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP 268

Query: 330 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQV----------HTQAQ 379
              QP +Q   Q Q  P   + QQ Q     Q    P +  QP V           +Q Q
Sbjct: 269 PIQQPPMQ---QPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325

Query: 380 PSV-QPQEHPPAQVSVQPP----------EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLE 428
           P V Q Q  P   +  QPP          +Q   QP  Q Q + +   Q   +V   G++
Sbjct: 326 PLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV-APGVQ 384

Query: 429 MPPDAVEAGGGMEKTLPEPVGTQVS 453
           M  +A+ A GGM      P  T VS
Sbjct: 385 MITEAL-AQGGMHIRARFPPTTAVS 408


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 83.2 bits (204), Expect = 9e-16
 Identities = 143/495 (28%), Positives = 180/495 (36%), Gaps = 99/495 (20%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQL-QQQQLQQQQL--LQLQQLLQQSPPQAPLPMAVSRGLP 60
            Q QQQQ  QQQQQLQQ QQQQL QQQQLQQQQL   Q QQ LQQ   Q            
Sbjct: 3899 QLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQ 3958

Query: 61   PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPAT-------YDTAGLT 113
             QQ QQ     Q      LLN S   R LL  Q Q   Q A+ P         + + G  
Sbjct: 3959 QQQQQQQFQQQQQQQQMGLLNQS---RTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGAL 4015

Query: 114  MPTATL----GNLRGYGMASPGLAAPS----------LTPPQLAT------PNLQ----- 148
             PT  L     N     ++S     PS           TP  +AT      P+L      
Sbjct: 4016 GPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQL 4075

Query: 149  ---QFFPQATRQSLLGPPPVGVPMNPSQ----FNLSGRNPQKQ----ARTSSSTTPNRKT 197
               Q  PQ    SL   PP+ +P    Q     + +G     Q    + + +S+ P+   
Sbjct: 4076 LLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA 4135

Query: 198  MPVEDKSDPPEGSEE----AAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELP 253
             P     D P    +      +P ++ P   +  P P         P P P       LP
Sbjct: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQP---------PKPGPVLQSGQGLP 4186

Query: 254  AKRLRSSEEPTEKEPPGQLQ--VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 311
               +     PT  +   QLQ  +   PQ R   P+Q Q           Q+      R L
Sbjct: 4187 GVGIM----PTVGQLRAQLQGVLAKNPQLRHLSPQQQQ-----------QLQALLMQRQL 4231

Query: 312  QVQAQVQSQTQP-RIPSTDTQ-------VQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE 363
            Q Q+Q   QT P + P T T         QP+L      QT P    LQ+    P+ Q  
Sbjct: 4232 Q-QSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGP----LQELGAGPRPQ-- 4284

Query: 364  AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLA--PEQTPVV 421
              P +   P       P + P    P   S Q P++  + P    Q+   A  P   P  
Sbjct: 4285 -GPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT 4343

Query: 422  VHVCG--LEMPPDAV 434
                G  LE PP  V
Sbjct: 4344 PKPQGPTLEPPPGRV 4358



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 107/444 (24%), Positives = 161/444 (36%), Gaps = 64/444 (14%)

Query: 4    QQQQQQLQQQQQQ----LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAP-----LPMA 54
            Q+Q  Q+++QQ++    + + + +Q QQQQ QQQQ  Q   +L  SP Q+P     LP  
Sbjct: 3575 QKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQ 3634

Query: 55   VSRGLPPQQPQQP--------LLNLQGTNSASLLNGSMLQRALLLQQLQ----GLDQFAM 102
            +  G   Q PQ P         L   G        G  L  AL  QQ Q    G    A 
Sbjct: 3635 LLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAG 3694

Query: 103  PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQ----LATPNLQQFFPQATRQS 158
            P   +    L         LR  G  S  L    L   Q    LA    QQ   Q  +Q 
Sbjct: 3695 PSGGFFPGNLA--------LRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQH 3746

Query: 159  LLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRM 218
            LLG   +                Q+Q +       N+   P      PP   +     ++
Sbjct: 3747 LLGQVAI----------------QQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQL 3790

Query: 219  DTPEDQD----LPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV 274
                 Q     L P    + +++   A  P+       P +++  ++      P    Q 
Sbjct: 3791 SPQPPQGPQGMLGPAQVAVLQQQHPGALGPQG------PHRQVLMTQSRVLSSPQLAQQG 3844

Query: 275  KAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 334
            +     R+   +Q Q      +      L   Q  ++    Q +   QP       Q Q 
Sbjct: 3845 QGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQ 3904

Query: 335  KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSV 394
            +LQ+Q Q Q   +  + QQ+Q+Q Q  Q+ + Q+Q+Q Q   Q Q     Q+    Q   
Sbjct: 3905 QLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ-----QQQQQLQQQQ 3959

Query: 395  QPPEQTHEQPHTQPQVSLLAPEQT 418
            Q  +Q  +Q   Q Q+ LL   +T
Sbjct: 3960 QQQQQQFQQQQQQQQMGLLNQSRT 3983



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 85/299 (28%), Positives = 118/299 (39%), Gaps = 40/299 (13%)

Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 189
           P      L+PP   +P      P+A+R   L PPP   PM+P         P + +R S 
Sbjct: 601 PPFEESPLSPPPEESPLSPP--PEASR---LSPPPEDSPMSPPPEESPMSPPPEVSRLSP 655

Query: 190 STTPNRKTMPVEDK--SDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 247
               +R + P E+   S PPE S     P    PE   L P PED        +P PE  
Sbjct: 656 LPVVSRLSPPPEESPLSPPPEES-----PTSPPPEASRLSPPPED-----SPTSPPPEDS 705

Query: 248 EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ 307
            AS  P   L S   P E+ P   L +  +PQ    +  +++ P L P   E  + PR +
Sbjct: 706 PASPPPEDSLMSL--PLEESP--LLPLPEEPQ----LCPRSEGPHLSPRPEEPHLSPRPE 757

Query: 308 PRVLQVQA-QVQSQTQPRIPS-TDTQVQPKLQKQAQ---TQTSPEHLVLQQKQVQPQLQQ 362
              L  QA +     QP  P       +P L  QA+       PE L L  +  +P L  
Sbjct: 758 EPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP 817

Query: 363 -EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP-PEQTHEQPHTQPQVSLLAPEQTP 419
              EP    QP+     +  + PQ   P    + P PE++H  P  +       PE+ P
Sbjct: 818 VPEEPCLSPQPE-----ESHLSPQSEEPC---LSPRPEESHLSPELEKPPLSPRPEKPP 868



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 95/428 (22%), Positives = 160/428 (37%), Gaps = 68/428 (15%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
            + ++++LQ++QQ   QLQ  Q QQQQ QQ  LL         P QA              
Sbjct: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLS-----APGPAQA-------------- 3294

Query: 64   PQQPLLNLQGTNSASLLNGSMLQRALLL--QQLQGLDQFAMP--PATYDTAGLTMPTATL 119
                 ++L    S+  L GS  Q +L L   +  GL Q  MP  P  +       P+  +
Sbjct: 3295 -----MSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAM 3349

Query: 120  GNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR 179
             + +G+ ++        L P Q + P L         Q  +G  P  + M P Q  +   
Sbjct: 3350 VSNQGHMLSGQHGGQAGLVPQQSSQPVLS--------QKPMGTMPPSMCMKPQQLAM--- 3398

Query: 180  NPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCP------ED 232
              Q+Q   S     +      ED  DP   ++  A   +     Q  +   P        
Sbjct: 3399 --QQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVS 3456

Query: 233  IAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPD 292
            +  ++ +  P  +        + + RS+ +P++  P          Q  +    Q Q  +
Sbjct: 3457 LLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRP----NPPTFAQGVINEADQRQYEE 3512

Query: 293  LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVL- 351
             L      Q L + Q +VL+ Q  V  +++  + +     +   ++  +       LV  
Sbjct: 3513 WL---FHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTE 3569

Query: 352  QQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVS 411
            QQ ++Q QL Q  + QK+     HT         E+   Q   Q  +Q  +Q H+   V 
Sbjct: 3570 QQSKIQKQLDQVRKQQKE-----HTNLM-----AEYRNKQQQQQQQQQQQQQQHS--AVL 3617

Query: 412  LLAPEQTP 419
             L+P Q+P
Sbjct: 3618 ALSPSQSP 3625



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 72/299 (24%), Positives = 112/299 (37%), Gaps = 35/299 (11%)

Query: 137 LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS-----SST 191
           L+PP   +P      P+A+R   L PPP  +P +P    L    P +++  S     S  
Sbjct: 449 LSPPPEESPTSPP--PEASR---LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503

Query: 192 TPNRKTMPV----EDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 247
           +P  ++ P     E    PPE  E    P ++TP        P     E+   +P PE  
Sbjct: 504 SPPPESSPFSPLEESPLSPPE--ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561

Query: 248 EASELP-AKRLR-SSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPR 305
             S  P A RL    EE     PP +  +   P+A    P   ++P L P   E+ + P 
Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP-LSPPPEESPLSP- 619

Query: 306 FQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 365
                        S+  P  P  D+ + P   +++     PE   L    V  +L    E
Sbjct: 620 ---------PPEASRLSP--PPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPE 667

Query: 366 PQKQVQPQVHTQAQPSVQPQE-HPPAQVS--VQPPEQTHEQPHTQPQVSLLAPEQTPVV 421
                 P   +   P  +     PP + S    PPE +   P  +  +  L  E++P++
Sbjct: 668 ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 124/502 (24%), Positives = 163/502 (32%), Gaps = 90/502 (17%)

Query: 3    SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPL---PMAVSRGL 59
            +QQ Q  +  +    QQ QQQQ  QQQ     L  LQQ L     Q  L   PM   + L
Sbjct: 3841 AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQL 3900

Query: 60   PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAMPPATYDTAGLTMPTA 117
              QQ  Q    LQ      L     LQ+  L   QQ Q L Q            L     
Sbjct: 3901 QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ 3960

Query: 118  TLGN--LRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFN 175
                   +       GL   S T   L +P  QQ      +Q  LGP   G+P  P Q  
Sbjct: 3961 QQQQQFQQQQQQQQMGLLNQSRT---LLSPQQQQ-----QQQVALGP---GMPAKPLQHF 4009

Query: 176  LSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235
             S   P     T   T   + T+      DP   SE    P         +   PE +A 
Sbjct: 4010 SS---PGALGPTLLLTGKEQNTV------DPAVSSEATEGPSTHQGGPLAIGTTPESMAT 4060

Query: 236  EKR---------------TPAPEPEPCEASELPAKRLRSSEEPTEK-------EPPGQLQ 273
            E                  P P+P+P      P  RL   ++              GQL 
Sbjct: 4061 EPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLG 4120

Query: 274  VKAQPQARMTVPKQTQTPDL----LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS-- 327
              +  +A  +VP     P +     P ++   +L   QP    ++  +Q+ T P+ P   
Sbjct: 4121 SGSSSEA-SSVPHLLAQPSVSLGDQPGSMTQNLLGPQQP---MLERPMQNNTGPQPPKPG 4176

Query: 328  ----------------TDTQVQPKLQKQAQTQTSPEHL-VLQQKQVQPQLQQEAEPQKQV 370
                            T  Q++ +LQ          HL   QQ+Q+Q  L Q    Q Q 
Sbjct: 4177 PVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQA 4236

Query: 371  QPQVHTQAQPSVQPQEHPPAQ--VSVQPPEQTHEQPHTQPQVSLLA---PEQTPVVVHVC 425
              Q     +P  Q     P Q  +  QP       P T P   L A   P+  P      
Sbjct: 4237 VRQTPPYQEPGTQTS---PLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPP------ 4287

Query: 426  GLEMPPDAVEAGGGMEKTLPEP 447
             L  PP A+  G  +    P P
Sbjct: 4288 RLPAPPGALSTGPVLGPVHPTP 4309



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 76/363 (20%), Positives = 116/363 (31%), Gaps = 70/363 (19%)

Query: 103  PPATYDTAGLTMPTATLG---NLRGY---------GMASPG---LAAPSLTPPQLATPN- 146
            PPA   T  +  PT   G   +  G+         G  SPG   L  P   P Q+ + + 
Sbjct: 2117 PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDP 2176

Query: 147  --------LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPN---- 194
                    L+  FP A       P P G P  P     S R    Q     +T P     
Sbjct: 2177 FGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRH 2236

Query: 195  ---------RKTMPVEDKSDPPE----GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPA 241
                     +   P  D    PE    G  +A+EP +  P   +     E   +E    +
Sbjct: 2237 QPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASS 2296

Query: 242  PE---------PEPCEASELPAKRLRSSE----------EPTEKEPPGQ-LQVKAQPQAR 281
            P            P   + L    L++ +             E + PG  L+ +  P A+
Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQ 2356

Query: 282  MTVPKQTQTPDLLPEA------LEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 335
               P     PD+           +  + PR QP   +    +  ++ P  P +     P+
Sbjct: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQ 2416

Query: 336  LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ 395
             Q  +Q+  +P  L  +     P   +   P    +P    Q++    P   PP     Q
Sbjct: 2417 SQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP---Q 2473

Query: 396  PPE 398
            PPE
Sbjct: 2474 PPE 2476



 Score = 37.7 bits (86), Expect = 0.045
 Identities = 78/375 (20%), Positives = 122/375 (32%), Gaps = 56/375 (14%)

Query: 129  SPGLAAPSLTP----PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFN--LSGRNPQ 182
            SP    P L+P    P L+    +      + +  L P P    ++P      LS R P+
Sbjct: 807  SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPR-PE 865

Query: 183  KQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDI---AKEKRT 239
            K         P  + +P+      P  S    EP +  P +  L P PE++      + +
Sbjct: 866  KPPEEPGQC-PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPS 924

Query: 240  PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV------KAQPQARMTVPKQTQTPDL 293
             +P+  P +    P   + ++  P    P G+L+        + P++ +  P        
Sbjct: 925  LSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAP-------- 976

Query: 294  LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSP--EHLVL 351
                LE  + P  +      +        P   S      P L +    Q SP  +H ++
Sbjct: 977  ---ILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLV 1033

Query: 352  QQKQVQPQLQQEAEPQKQVQP--------------QVHTQAQPSVQPQEHPPAQVSVQPP 397
             Q     Q    A P     P              ++H      V   E P  +     P
Sbjct: 1034 PQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE-----P 1088

Query: 398  EQTHEQPHTQPQVSLLAPEQTPVVVHVCGL---EMPPDAVEAGGGMEKTLPEPVGTQVSM 454
              T   P     +S  AP   P +    GL     P D ++A G      PEP  T  S+
Sbjct: 1089 SATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQ----PEPGQTPGSL 1144

Query: 455  EEIQNESACGLDVGE 469
                  S   LD  E
Sbjct: 1145 ASELKGSPVLLDPEE 1159



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 72/350 (20%), Positives = 121/350 (34%), Gaps = 50/350 (14%)

Query: 199  PVEDKSDPPEGSEEAAEPRMDTPEDQDLP----------PCPEDIAKEKRTPAPEPEPCE 248
            P+  +  PP  ++ A+EPR+ +   +  P          PC   IA  K  PAP      
Sbjct: 3093 PLGPEERPPPAAD-ASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLG 3151

Query: 249  ASELPAKRLRSSEEPTEKEPP----GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 304
                P + +  S +      P    G    KA   A    P    TP  L     + +L 
Sbjct: 3152 LGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLE 3211

Query: 305  RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA 364
            +F+        +  + T P  P+       K++        P    L  + +    ++E 
Sbjct: 3212 KFE-------LESGALTLPGGPAASGDELDKMESSLVASELP----LLIEDLLEHEKKEL 3260

Query: 365  EPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHV 424
            + ++Q+  Q+    Q   Q Q+H  + +S   P Q    PH     SL   +Q       
Sbjct: 3261 QKKQQLSAQLQPAQQQQQQQQQH--SLLSAPGPAQAMSLPHEGSSPSLAGSQQQL----- 3313

Query: 425  CGLEMPPDAVEAGGGMEKTLPEP-VGTQVSMEEIQNESACGLDVGECENRAREMPGVWGA 483
                    ++   G  +  LP+P + TQ     +Q   A  + +    N+   + G  G 
Sbjct: 3314 --------SLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAM--VSNQGHMLSGQHGG 3363

Query: 484  GGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 533
               L   + Q S     S  P+  +P    S+   P   +   + A  FF
Sbjct: 3364 QAGL---VPQQSSQPVLSQKPMGTMP---PSMCMKPQQLAMQQQLANSFF 3407


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 123/474 (25%), Positives = 181/474 (38%), Gaps = 65/474 (13%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ--SPPQAPLP----MAVSR 57
           QQQQQQ QQQQQQ QQ QQQQLQ +  QQ Q  Q Q +  Q  +P Q P+P       S 
Sbjct: 265 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSG 324

Query: 58  GLPPQQPQQPLLNL---QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTM 114
            L P   Q  L  +   QG   A  L G M Q+      L  +   + PP  Y       
Sbjct: 325 ALQPPPAQGSLGTMTANQGWKKAP-LPGPMQQQLQARPSLATVQTPSHPPPPYPFGS--- 380

Query: 115 PTATLGNLRGYGMASPG----------LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164
             A+  +     M++PG             PS  P  L  P+L    P ++  S     P
Sbjct: 381 QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSP 440

Query: 165 VGVP-MNPSQFNLSGR----NPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMD 219
              P +N +Q  +  R    NP  Q      ++P R  M V+  + PP       +P   
Sbjct: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPM-VQQGNVPPNFMVMQQQPPNQ 499

Query: 220 TPED---------QDLPP-------CPEDI-AKEKRTPAPEPEPCEASELPA-KRLRSSE 261
            P+          + LPP        P  +  +   T A  P    A +L A + ++ + 
Sbjct: 500 GPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAG 559

Query: 262 EPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQT 321
                 P  Q+QV   P   M         ++  +      +P  Q  +  +Q Q Q   
Sbjct: 560 GQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVP--QVNLSNMQGQPQQGP 617

Query: 322 QPRIPSTDTQVQPKLQKQAQTQ--TSPEH-LVLQQKQVQPQLQQEAEPQKQVQPQVHTQA 378
             ++     Q+ P   +  Q Q   +P++ ++L + Q+ PQ Q    P  Q         
Sbjct: 618 PSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQ-------NL 670

Query: 379 QPSVQPQEHPPAQVSVQPPEQTHEQPHTQ---PQVSLLAPEQTPVVVHVCGLEM 429
            PS Q    P   +S Q P+     PH Q   PQ  +L  +Q P++  +   +M
Sbjct: 671 GPSPQRMTPPKQMLSQQGPQMM--APHNQMMGPQGQVLL-QQNPMIEQIMTNQM 721



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 99/444 (22%), Positives = 163/444 (36%), Gaps = 45/444 (10%)

Query: 1    MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-QLQQLLQQSPPQ-----APLPMA 54
            M SQQ  Q +    Q +    Q  LQQ  + +Q +  Q+Q   QQ   Q      P P  
Sbjct: 683  MLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQ 742

Query: 55   VSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGLDQFAMPPATYDTAGL 112
            + RG  P   Q  ++   G  S  +L   G +      +  +QG       P+ +     
Sbjct: 743  IMRGPTPNM-QGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQH 801

Query: 113  TMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQS-------LLGPPPV 165
              P  T  N        P +   S+    +  P++Q     +   +           P  
Sbjct: 802  GDPATTANNDVSLSQMMPDV---SIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFS 858

Query: 166  GVPMNPSQFNLSGRNPQKQARTSSS-TTPNRKTMPVEDKSDPPEG-SEEAAEPRMDTPED 223
            G P N +Q +  G+NP        + T+P    +   D S    G + +      + P+ 
Sbjct: 859  GAP-NGNQMSC-GQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKK 916

Query: 224  QDLPPCPEDIAKEKRTPAPEPEPCEASE---LPAKRLRSSEEPTEKEPPGQLQVKAQPQA 280
            +  P   ++  ++  TP   P   E ++   LP ++  + +    K P    +   +P  
Sbjct: 917  KKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLP----EFSNRPPG 972

Query: 281  RMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA 340
              + P + +    +P  L   V P  QP   Q Q Q+  Q QP  PS     QP+ Q+Q 
Sbjct: 973  YPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPS-----QPQSQQQQ 1027

Query: 341  QTQTSPEHLVLQQKQVQ----PQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP 396
            Q Q     +++ Q+  +    P  Q    P+  + P   +Q  P +Q     P  VS+Q 
Sbjct: 1028 QQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPD--SQRMP-MQQSGSVPVMVSLQG 1084

Query: 397  PEQTHEQPHTQPQVSLLAPEQTPV 420
            P      P  Q    +  P  TP+
Sbjct: 1085 PASVPPSPDKQ---RMPMPVNTPL 1105



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 75/289 (25%), Positives = 111/289 (38%), Gaps = 35/289 (12%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL-PPQ 62
            QQ Q QL QQQQ     Q Q  QQQQ QQQ ++ L  ++QQ P    LP  VS+ + PP+
Sbjct: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML--MMQQDPKSVRLP--VSQNVHPPR 1058

Query: 63   QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTAT-LGN 121
             P    LN          +GS+     ++  LQG    A  P + D   + MP  T LG+
Sbjct: 1059 GP----LNPDSQRMPMQQSGSV----PVMVSLQGP---ASVPPSPDKQRMPMPVNTPLGS 1107

Query: 122  LRGYGMASPGLAAPSLTP-PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
                 +       PS +P  ++A+       P+A+      P   G P N     +  +N
Sbjct: 1108 NSRKMVYQESPQNPSSSPLAEMAS------LPEASGSE--APSVPGGPNNMPSHVVLPQN 1159

Query: 181  PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAE----PRMDTPEDQDLPPCPEDIAKE 236
                       +P   T     +  PP  S  ++     P +  P     P  P   +  
Sbjct: 1160 QLMMTGPKPGPSPLSATQGATPQ-QPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPR 1218

Query: 237  ---KRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 282
                +TP   P   E SE+     R +       PP Q+ +   P+  +
Sbjct: 1219 PYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPP-QINIPLPPRPNL 1266



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 47/208 (22%)

Query: 217 RMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPG-QLQVK 275
           RM+ P    +PP   +++     P P PE    +  PA    S  +  +    G  +Q +
Sbjct: 175 RMNNPATVMIPP-GGNVSSSMMAPGPNPELQPRTPRPA----SQSDAMDPLLSGLHIQQQ 229

Query: 276 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 335
           + P   +  P     P                   + V  Q+        P+   Q+Q +
Sbjct: 230 SHPSGSLAPPHHPMQP-------------------VSVNRQMN-------PANFPQLQQQ 263

Query: 336 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP-SVQPQEHPPAQVSV 394
            Q+Q Q Q        QQ+Q Q Q QQ+ + Q +  PQ H Q QP  ++PQ   P QV V
Sbjct: 264 QQQQQQQQ--------QQQQQQQQQQQQQQLQAR-PPQQHQQQQPQGIRPQFTAPTQVPV 314

Query: 395 QP-----PEQTHEQPHTQPQVSLLAPEQ 417
            P     P    + P  Q  +  +   Q
Sbjct: 315 PPGWNQLPSGALQPPPAQGSLGTMTANQ 342


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 76.6 bits (187), Expect = 9e-14
 Identities = 89/304 (29%), Positives = 119/304 (39%), Gaps = 56/304 (18%)

Query: 5   QQQQQLQQQQQQLQ---QLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
           Q QQQ+QQQQQQLQ   QLQ QQ QQQQ QQQQ  Q QQ LQ  PP    PM        
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ--QQQQALQAQPPIQQPPM-------- 275

Query: 62  QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121
           QQPQ P          S      LQ+    Q  Q   Q   PP   +      P +    
Sbjct: 276 QQPQPP---------PSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQP 326

Query: 122 LRGYGMASPG-----------LAAPSLT--PPQLATPNLQQFFPQATRQSLLGPPPVGVP 168
           L     A PG           + AP +   PP       QQ   Q  + + +  P V V 
Sbjct: 327 LVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVS 386

Query: 169 MNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPP 228
            + S   LS  +P +Q +T  S  P            PP+ S +  +P      +    P
Sbjct: 387 QS-SLPMLSSPSPGQQVQTPQSMPP------------PPQPSPQPGQPSSQPNSNVSSGP 433

Query: 229 CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 288
            P   +     P+P P+P + S + A+  ++   P+    PG L     P + M+    +
Sbjct: 434 AP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS----PGPLNTPVNPSSVMSPAGSS 485

Query: 289 QTPD 292
           Q  +
Sbjct: 486 QAEE 489



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 91/335 (27%), Positives = 122/335 (36%), Gaps = 31/335 (9%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQ---------LLQLQQLLQQSPPQAP--LP 52
           QQQQQQ QQQQQ   Q QQQQ QQQQ Q QQ         ++Q QQ LQQ   Q    + 
Sbjct: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIK 222

Query: 53  MAVSRGLPPQQPQQPL-----LNLQGTNSASLLNGSMLQRALLLQ---QLQGLDQFAMPP 104
           +        QQ QQ L     L LQ             Q+AL  Q   Q   + Q   PP
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282

Query: 105 ATYDTAGLTMPTATLGNLRGYGMASPGLA--APSLTPPQLATPNLQQFFPQATRQSLLGP 162
           +      L     T  +        P +A   PS  PPQ  T  L         Q L   
Sbjct: 283 SQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342

Query: 163 PPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVE----DKSDPPEGSEEAAEPRM 218
           PP+     P         PQ Q + ++  T     M        +S  P  S  +   ++
Sbjct: 343 PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQV 402

Query: 219 DTPEDQDLPPCP-----EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQ 273
            TP+    PP P     +  ++     +  P P  +S LP+   + S+ P     P    
Sbjct: 403 QTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFS 462

Query: 274 VKAQPQARMTV-PKQTQTPDLLPEALEAQVLPRFQ 307
           V +       V P    +P    +A E Q L + +
Sbjct: 463 VPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLK 497



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 88/333 (26%), Positives = 135/333 (40%), Gaps = 61/333 (18%)

Query: 241 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 300
           AP      ++  P  +L+  +   +++   Q Q + Q QA +   +Q Q      +A ++
Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194

Query: 301 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 359
            +  +FQ  V Q Q  Q Q Q Q  +     Q Q ++Q+Q Q       L LQQ+Q Q Q
Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254

Query: 360 LQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 418
            QQ+ + Q  Q QP +    QP +Q  + PP+Q   Q  +Q H   H QP      P+Q 
Sbjct: 255 QQQQQQQQALQAQPPIQ---QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQP 308

Query: 419 PVVVHVCGLEMPP---------DAVEAGGGMEKTLP-------------EPVGTQVSMEE 456
           PV  +    ++PP          A    G M  T P              PV  QV  ++
Sbjct: 309 PVAQNQPS-QLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367

Query: 457 IQNESACGLDVGECENRAREM--PGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPS-- 512
              ++A          +A +M  PGV  +  SL +    S   +  +   + P P+PS  
Sbjct: 368 TAVQTA----------QAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ 417

Query: 513 ---------DSVSSTPAAT-----STPSKQALQ 531
                     +VSS PA +      +PS Q  Q
Sbjct: 418 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ 450



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 12/91 (13%)

Query: 326 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE---------AEPQKQVQPQVHT 376
           P   + + P       T T    L LQQ  +Q Q QQ+          + Q+Q Q Q   
Sbjct: 130 PPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQF 189

Query: 377 QAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 407
           QAQ S   Q+    Q  VQ  +Q  +Q   Q
Sbjct: 190 QAQQSAMQQQF---QAVVQQQQQLQQQQQQQ 217


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 119/447 (26%), Positives = 161/447 (36%), Gaps = 76/447 (17%)

Query: 8    QQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQP 67
            Q L+QQQQQ QQ QQQQ QQQQ QQQQ  Q QQ    S                 Q Q P
Sbjct: 2715 QLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTS-----------------QVQVP 2757

Query: 68   LLNLQGTNSASL-LNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYG 126
             +  Q  + A +   G +    L+  Q Q L     PP     +    PTA         
Sbjct: 2758 QIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQ-------- 2809

Query: 127  MASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLS----GRNPQ 182
                 +   +  PPQ  +P L          ++  P P  +    +  NL      R P 
Sbjct: 2810 -----VQVQTSQPPQQQSPQL---------TTVTAPRPGALLTGTTVANLQVARLTRVPT 2855

Query: 183  KQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 242
             Q +                 + PP  S  AA   + +P    LP     I+     P  
Sbjct: 2856 SQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAV--VSSPGVTTLPMNVAGISVAIGQPQK 2913

Query: 243  E------PEPCEASEL-----PAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTP 291
                    +P    +L      A + + + +P   + P  +Q K   Q   T   Q +  
Sbjct: 2914 AAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVA 2973

Query: 292  DLLPEALEAQVL--PRFQPRVL----QVQAQVQSQTQPRIPSTDTQVQPKLQ-KQAQTQT 344
                 AL+ Q L  P  Q + L    QVQ Q+Q    P++    T V    Q   A  Q 
Sbjct: 2974 YAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQA 3033

Query: 345  SPEHLVL-------QQKQVQPQLQQEAE--PQKQVQPQVHTQAQPSVQPQEHP-PAQV-- 392
            SP+ + L       QQ Q+ P +   A+   QK +Q QV T A   +Q    P PAQV  
Sbjct: 3034 SPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPA 3093

Query: 393  SVQPPEQTHEQPHTQPQVSLLAPEQTP 419
            S   P Q  +     P V L  P + P
Sbjct: 3094 SSDSPSQQPKLQMRVPAVRLKTPTKPP 3120



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 105/454 (23%), Positives = 154/454 (33%), Gaps = 80/454 (17%)

Query: 16   QLQQLQQQQLQQQQ--LQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQG 73
            Q+  L+ +++ +++  L  QQ  Q   + Q  PPQ   P       PPQQP  PL   Q 
Sbjct: 2476 QVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPP------PPQQPPPPLPQPQA 2529

Query: 74   TNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLA 133
                    GS         Q Q   Q    P          P  T G   G      G  
Sbjct: 2530 A-------GSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTG---GSAAVLAGTI 2579

Query: 134  APSLTPPQLAT--------PNLQQFFPQATRQSL-------LGPPPVGVPMNPSQFNLSG 178
              S+T   + T         N     P AT QS+       + P  +  P   +   +  
Sbjct: 2580 KTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVH 2639

Query: 179  RNPQKQARTSSST-TPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 237
              P  +A  S +T TP+  +M         +G               +L P    +    
Sbjct: 2640 TQPPPRAVGSPATATPDLVSMAT------TQGVRAVTSVTASAVVTTNLTP----VQTPA 2689

Query: 238  RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEA 297
            R+  P+       +LP K +           P   Q+  Q Q +    +Q Q        
Sbjct: 2690 RSLVPQVSQATGVQLPGKTI----------TPAHFQLLRQQQQQQQQQQQQQ-------- 2731

Query: 298  LEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ 357
               Q   + Q +  Q Q Q  + +Q ++P    Q Q   Q +A  + +PEHL+  QKQ  
Sbjct: 2732 ---QQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKL 2788

Query: 358  PQLQQEAEPQKQ---VQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLA 414
                Q   PQ Q    QP    Q Q S  PQ+  P   +V           T P+   L 
Sbjct: 2789 QMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTV-----------TAPRPGALL 2837

Query: 415  PEQTPVVVHVCGL-EMPPDAVEAGGGMEKTLPEP 447
               T   + V  L  +P   ++A G M+   P+P
Sbjct: 2838 TGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQP 2871



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 28/120 (23%)

Query: 223  DQDLPPCP------EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 276
            D+ LPP        E IAKEK+  A +              + +++P   +PP       
Sbjct: 2469 DKPLPPIQVASLRAERIAKEKKALADQ--------------QKAQQPAVAQPP------- 2507

Query: 277  QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 336
             PQ +   P Q Q P  LP+   A   P   P  +Q Q Q Q QTQP+      + QP +
Sbjct: 2508 PPQPQPPPPPQ-QPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAI 2566



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 64/313 (20%), Positives = 102/313 (32%), Gaps = 51/313 (16%)

Query: 291  PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV 350
            P +   +L A+ + + + + L  Q + Q     + P    Q  P  Q+       P+   
Sbjct: 2473 PPIQVASLRAERIAK-EKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAG 2531

Query: 351  LQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQV 410
             Q     P +Q + +PQ Q QPQ                    VQ P +      T    
Sbjct: 2532 SQPPAGPPAVQPQPQPQPQTQPQ-------------------PVQAPAKAQPAITTGGSA 2572

Query: 411  SLLAPEQTPVVVHVCGLEMPPDAVEAG--------------GGMEKTLPEPVGTQV---- 452
            ++LA     +   V G  MP  AV                   + K L  PV        
Sbjct: 2573 AVLA---GTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTP 2629

Query: 453  ---SMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVP 509
               +  ++ +       VG       ++  +    G   VT + +S   A  T  LTPV 
Sbjct: 2630 GGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTAS---AVVTTNLTPVQ 2686

Query: 510  RPSDSV---SSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHM 566
             P+ S+    S       P K        + +     QQ+ Q    + Q QQ+  + Q  
Sbjct: 2687 TPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQ-QQQQQQQQQQQQQQQQQQQQQQQQQ 2745

Query: 567  SQACLLSLLPVPR 579
             Q    S + VP+
Sbjct: 2746 QQTTTTSQVQVPQ 2758



 Score = 33.9 bits (76), Expect = 0.64
 Identities = 48/183 (26%), Positives = 72/183 (39%), Gaps = 17/183 (9%)

Query: 17  LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP--PQQPQQPLLNLQGT 74
           LQ  QQ Q+ + Q Q Q  ++ QQ      P  P+P   S  LP  P QP Q  L++  T
Sbjct: 574 LQFAQQPQVVEAQTQLQIPVKTQQ------PNVPIPAPPSSQLPIPPSQPAQLALHVP-T 626

Query: 75  NSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGL-TMPTATLGNLRGYGMA-SPGL 132
                +  S L     L Q+    +  + PA      L T  T++L  + G G   SP  
Sbjct: 627 PGKVQVQASQLSS---LPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPAR 683

Query: 133 AAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTT 192
           ++P   P       L    P  +R   +       P +P+Q   S ++  +   T   T 
Sbjct: 684 SSPVNRPSSATNKALS---PVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQITL 740

Query: 193 PNR 195
            N+
Sbjct: 741 ENQ 743



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 76/291 (26%), Positives = 102/291 (35%), Gaps = 59/291 (20%)

Query: 308 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHL--------VLQQKQVQPQ 359
           P+  Q+  Q QSQ Q   PST   VQ            P  L         L       Q
Sbjct: 520 PQAAQLAGQRQSQQQYD-PSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQ 578

Query: 360 LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHE---QPHTQPQVSLLAPE 416
             Q  E Q Q+Q  V TQ QP+V P   PP+     PP Q  +      T  +V + A +
Sbjct: 579 QPQVVEAQTQLQIPVKTQ-QPNV-PIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQ 636

Query: 417 QTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRARE 476
            + +   V    +P D            P P+ T  S   +   S  G            
Sbjct: 637 LSSLPQMVASTRLPVDPA-------PPCPRPLPTS-STSSLAPVSGSG------------ 676

Query: 477 MPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYI 536
            PG   A  S  V    S+ ++A S V      R    V+S P    +P++ A       
Sbjct: 677 -PGPSPARSS-PVNRPSSATNKALSPV----TSRTPGVVASAPTKPQSPAQNA------- 723

Query: 537 CKASCSSQQEFQDHMSEP-----QHQQRLGEIQH---MSQACLLSLLPVPR 579
                SSQ   QD ++E      Q  QR+ E++     SQ  L  L   PR
Sbjct: 724 ----TSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPR 770



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 46/180 (25%), Positives = 64/180 (35%), Gaps = 35/180 (19%)

Query: 125  YGMASPG--LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPV------------GVPMN 170
            YG    G  +A PS  PP+ A P      PQ     L G PP+              P  
Sbjct: 1432 YGQKPEGRTVAFPSTHPPRTAAPTTASAAPQG---PLRGRPPIATFSANPEAKAAAAPFQ 1488

Query: 171  PSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCP 230
             SQ + S   P+ Q  ++SST  +    P        + + +A+ P    P+    P  P
Sbjct: 1489 TSQASASA--PRHQPASASSTAAS----PAHPAKLRAQTTAQASTPGQPPPQ----PQAP 1538

Query: 231  EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQT 290
               A +   P     P +A      RL S     E     QL     PQ+R+  P+   T
Sbjct: 1539 SHAAGQSALPQRLVLPSQAQ----ARLPSG----EVVKIAQLASITGPQSRVAQPETPVT 1590


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 81/312 (25%), Positives = 123/312 (39%), Gaps = 62/312 (19%)

Query: 153  QATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQAR--------TSSSTTPNRKTMPVEDKS 204
            Q T Q  L P  V V   P Q  +    P    +        T+++T     T      +
Sbjct: 2174 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAA 2233

Query: 205  DPPEGSEEAAEPRMDTPEDQDLPPC------PEDIAKEKRTPAPEPEPCEASELPAK--- 255
               E  +    P+M   +D+ LPP       P +   +   P+ +P+P    + PA+   
Sbjct: 2234 GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEV 2293

Query: 256  ---------RLRSSEEPTEKEPPG------QLQVKAQPQA--------RMTVPKQTQ--- 289
                        SS  P+E +P        Q+  ++QPQ+        R+  P QT+   
Sbjct: 2294 QTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRP 2353

Query: 290  -TPDLLPEALEAQVLPR------FQPRV-LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQ 341
             TP  L    ++QV          QP   LQ+ +Q Q Q+QP++ S+   +         
Sbjct: 2354 STPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQV 2413

Query: 342  TQTSPEHLVLQQKQVQ------PQLQQEAEPQKQVQPQV--HTQAQPSVQPQE---HPPA 390
            T +SP    LQ +Q Q      PQLQQ+ +   Q+Q QV    QAQ S  PQ+     P 
Sbjct: 2414 TVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPI 2473

Query: 391  QVSVQPPEQTHE 402
            Q+      QTH+
Sbjct: 2474 QIQQSSAVQTHQ 2485



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 49/157 (31%), Positives = 73/157 (46%), Gaps = 11/157 (7%)

Query: 277  QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 335
            Q Q++++   Q      LP A  + V P   QP+  Q  AQ Q QTQP+ P+     QP+
Sbjct: 2238 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2292

Query: 336  LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--KQVQPQVHTQAQPSVQPQEHPPAQVS 393
            +Q Q + QT          + QP   Q ++PQ   Q QPQ + Q Q  V+ Q   P+Q  
Sbjct: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQS--PSQTR 2350

Query: 394  VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 430
            ++P   +   P  Q QV     +  P+  H   L++P
Sbjct: 2351 IRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2386



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 103/439 (23%), Positives = 177/439 (40%), Gaps = 55/439 (12%)

Query: 3    SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
            S  Q  + QQ Q +L   Q  QL Q     Q L  + Q   Q+  Q  L       LP  
Sbjct: 2133 SASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPG- 2191

Query: 63   QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNL 122
             P Q L+       A++ NG++ QR L             P AT  T   T  T      
Sbjct: 2192 -PGQQLMQ------AAMPNGTV-QRFLFT-----------PLATTATTASTTTTTVSTTA 2232

Query: 123  RGYGMASPGLAAP--------SLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQF 174
             G G       +P        +L P Q ++    +  PQ T Q    P P   P +P+Q 
Sbjct: 2233 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQ-TAQPSAQPQPQTQPQSPAQP 2291

Query: 175  NLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEA---------AEPRMDTPEDQD 225
             +  + P+ Q +T+ S+    +  P   +S  P+ + ++         +  R+ +P    
Sbjct: 2292 EVQTQ-PEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTR 2350

Query: 226  L-PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTV 284
            + P  P  ++  +++   + +   +  +P +   S + P++ +P  Q QV++  Q   + 
Sbjct: 2351 IRPSTPSQLSPGQQS---QVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSG 2407

Query: 285  PKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 344
                Q     P   + Q+  + QP+V+ V  Q+Q Q Q       +Q+Q ++  Q Q Q 
Sbjct: 2408 QTLNQVTVSSPSRPQLQI-QQPQPQVIAVP-QLQQQVQVL-----SQIQSQVVAQIQAQQ 2460

Query: 345  S--PEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHE 402
            S  P+ + LQ   +  Q+QQ +  Q      V T    SVQ Q     Q+  Q  ++  +
Sbjct: 2461 SGVPQQIKLQ---LPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQ 2517

Query: 403  QPHTQPQVSLLAPEQTPVV 421
            Q   + + +L A  Q+ ++
Sbjct: 2518 QIEIKREHTLQASNQSEII 2536



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%)

Query: 648 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 700
           + D   E +  E+++  ++E+           +GD EE +D ED+EE E+EE+
Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169



 Score = 30.0 bits (66), Expect = 9.3
 Identities = 17/60 (28%), Positives = 26/60 (43%)

Query: 227 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 286
           P  P   A E+  PAP P P   +  P   LRS    + +      Q +  P+ R++ P+
Sbjct: 9   PKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPR 68


>gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens]
          Length = 858

 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 122/471 (25%), Positives = 165/471 (35%), Gaps = 88/471 (18%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
           Q  QQ+   QQQ   LQ   LQQQ L   QL  L  + Q S             +  Q P
Sbjct: 73  QYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGSNVSAQAP 132

Query: 65  QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRG 124
            Q         S+S+   +    A LL + Q ++  A        +G+      LGN   
Sbjct: 133 AQ---------SSSINLAASPAAAQLLNRAQSVNSAA-------ASGIAQQAVLLGN--- 173

Query: 125 YGMASPGLAAPSLTPPQLATPNLQQFFPQ---ATRQSLLGPPPVGVPMNPSQF-NLSGRN 180
              +SP L A            +  F P    AT Q  LG      P  P+Q  NL+ R 
Sbjct: 174 --TSSPALTASQ--AQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRT 229

Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240
            Q  A  +S  TP +  +P       P GS             Q LP           TP
Sbjct: 230 QQTPAAAASGPTPTQPVLPSLALKPTPGGS-------------QPLP-----------TP 265

Query: 241 APEPEPCEASELPAK-RLRSSEEPTEKEPPGQLQVKAQPQAR----MTVPKQTQTPDLLP 295
           A      +AS   AK  +  S     K+  G   V    + R     TVP     P + P
Sbjct: 266 AQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAP 325

Query: 296 EALEA---QVLPRFQPRVLQVQAQVQSQTQPRIPS-TDTQVQPKLQKQAQTQTSPEHLVL 351
              +    Q+LP+   + LQ Q  +Q Q QP+       Q +P LQ +   Q +    V 
Sbjct: 326 AYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLAS---VS 382

Query: 352 QQKQVQPQLQQEAEPQKQVQPQVHTQA------QPSVQPQEHPPAQVSVQPPEQTHEQ-- 403
               +QP  +  A P   V P +  Q       +P    Q HPP   +   P+  H +  
Sbjct: 383 PSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDT--GPQNGHPEGV 440

Query: 404 --------PHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPE 446
                    HT   +  L P   P     C   +P D  E   G EK++PE
Sbjct: 441 PHTPQRRFQHTSAVILQLQPASPP---QQC---VPDDWKEVAPG-EKSVPE 484


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 71/255 (27%), Positives = 90/255 (35%), Gaps = 28/255 (10%)

Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDT 220
           GPPP+  P  P         P +         PN   MP      PP G      P    
Sbjct: 42  GPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMP 101

Query: 221 PEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQA 280
           P    +PP P  +        P   P  A   PA           K P G++       A
Sbjct: 102 PPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY---NA 152

Query: 281 RMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA 340
           R      T+ PD +    ++++ P     +L  QAQVQ+Q Q +      Q Q + Q QA
Sbjct: 153 RTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQAQ-----AQAQAQAQAQA 201

Query: 341 QTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQT 400
           Q Q         Q Q Q Q Q +A+ Q Q Q Q   QAQ   Q Q     Q  VQ   Q 
Sbjct: 202 QAQA--------QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQA 253

Query: 401 HEQPHTQPQVSLLAP 415
                + P  S  AP
Sbjct: 254 QAVGASTPTTSSPAP 268



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 75/345 (21%), Positives = 122/345 (35%), Gaps = 43/345 (12%)

Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 189
           P +  P   PP +  P+LQ       R   + PP   +P  P      G  P     T +
Sbjct: 77  PPMPPPGGIPPPMGPPHLQ-------RPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPA 129

Query: 190 STTPNRKTMPVEDKSDPPEG--------SEEAAEPRMD---TPEDQDLPP---CPEDIAK 235
              P  + + VE+K+  P+G        + E+A  + D     +  +L P       +  
Sbjct: 130 --LPPTEEIWVENKT--PDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQA 185

Query: 236 EKRTPAPEPEPCEA---SELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPD 292
           + +  A      +A   ++  A+    ++   + +   Q Q +AQ QA+     Q Q   
Sbjct: 186 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQA 245

Query: 293 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 352
            +   ++AQ +    P        V + T    PS+ T         AQT ++P      
Sbjct: 246 QVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTP----TT 301

Query: 353 QKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL 412
           Q Q        A P   V     T       PQ HP       PP      PH+ PQ + 
Sbjct: 302 QDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHP----QTLPP----AVPHSVPQPTT 353

Query: 413 LAPEQTPVVVHVCGLEMPPDAVEAGG---GMEKTLPEPVGTQVSM 454
             P   PV+V    + +P   +   G   GM   +   +  QV++
Sbjct: 354 AIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAI 398



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 72/314 (22%), Positives = 107/314 (34%), Gaps = 55/314 (17%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
           Q Q Q Q Q Q   Q Q Q   Q Q+Q Q   Q+Q              AV    P    
Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQ------------AQAVGASTPTTSS 265

Query: 65  QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYD---TAGLTMPTATLGN 121
             P ++   ++S      S    A        + Q    P T D   ++ +++ T T+  
Sbjct: 266 PAPAVSTSTSSSTPSSTTSTTTTA------TSVAQTVSTPTTQDQTPSSAVSVATPTVSV 319

Query: 122 LRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGP----PPVGVPMNPSQFNLS 177
                 A+P    P    PQ   P +    PQ T      P    PP  VP+      L 
Sbjct: 320 STPAPTATPVQTVPQ-PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLP 378

Query: 178 G------------RNPQKQARTSSSTTPNRKTMPVEDKSDPPEG-----SEEAAEPRMDT 220
           G             +PQ     S +T      +    +    +G     +    E   + 
Sbjct: 379 GVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEK 438

Query: 221 PED-QDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEKEPPGQ 271
           P++ ++     E I +  + P+ EP P E       E P K ++     EE TE+E   Q
Sbjct: 439 PQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQ 498

Query: 272 LQVKAQPQARMTVP 285
              KA+P A   +P
Sbjct: 499 ---KAKPVATAPIP 509


>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
           sapiens]
          Length = 1098

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 71/255 (27%), Positives = 90/255 (35%), Gaps = 28/255 (10%)

Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDT 220
           GPPP+  P  P         P +         PN   MP      PP G      P    
Sbjct: 42  GPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMP 101

Query: 221 PEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQA 280
           P    +PP P  +        P   P  A   PA           K P G++       A
Sbjct: 102 PPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY---NA 152

Query: 281 RMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA 340
           R      T+ PD +    ++++ P     +L  QAQVQ+Q Q +      Q Q + Q QA
Sbjct: 153 RTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQAQ-----AQAQAQAQAQA 201

Query: 341 QTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQT 400
           Q Q         Q Q Q Q Q +A+ Q Q Q Q   QAQ   Q Q     Q  VQ   Q 
Sbjct: 202 QAQA--------QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQA 253

Query: 401 HEQPHTQPQVSLLAP 415
                + P  S  AP
Sbjct: 254 QAVGASTPTTSSPAP 268



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 97/481 (20%), Positives = 170/481 (35%), Gaps = 84/481 (17%)

Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 189
           P +  P   PP +  P+LQ       R   + PP   +P  P      G  P     T +
Sbjct: 77  PPMPPPGGIPPPMGPPHLQ-------RPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPA 129

Query: 190 STTPNRKTMPVEDKSDPPEG--------SEEAAEPRMD---TPEDQDLPP---CPEDIAK 235
              P  + + VE+K+  P+G        + E+A  + D     +  +L P       +  
Sbjct: 130 --LPPTEEIWVENKT--PDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQA 185

Query: 236 EKRTPAPEPEPCEA---SELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPD 292
           + +  A      +A   ++  A+    ++   + +   Q Q +AQ QA+     Q Q   
Sbjct: 186 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQA 245

Query: 293 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 352
            +   ++AQ +    P        V + T    PS+ T         AQT ++P      
Sbjct: 246 QVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTP----TT 301

Query: 353 QKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL 412
           Q Q        A P   V     T       PQ HP       PP      PH+ PQ + 
Sbjct: 302 QDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHP----QTLPP----AVPHSVPQPTT 353

Query: 413 LAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECEN 472
             P   PV+V       PP  V   G     +P P+     M+ +    +C         
Sbjct: 354 AIPAFPPVMV-------PPFRVPLPG-----MPIPLPGVAMMQIV----SCPYVKTVATT 397

Query: 473 RAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPA--ATSTPSKQAL 530
           +   +PG+                       P+ P+  P  +++++PA  A +T   +  
Sbjct: 398 KTGVLPGM---------------------APPIVPMIHPQVAIAASPATLAGATAVSEWT 436

Query: 531 QFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLL--SLLPVPRDVLETEDEE 588
           ++     K    + +  +    +PQ  +   +++   +  +   S  P+P   +ETE+E+
Sbjct: 437 EYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLP---METEEED 493

Query: 589 P 589
           P
Sbjct: 494 P 494



 Score = 33.5 bits (75), Expect = 0.84
 Identities = 74/319 (23%), Positives = 111/319 (34%), Gaps = 44/319 (13%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62
           Q Q Q Q Q Q   Q Q Q   Q Q+Q Q   Q+Q Q +  S P    P  AVS      
Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277

Query: 63  QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMP------PATYDTAGLTMP- 115
            P         T +A+ +  ++       Q        A P      PA   T   T+P 
Sbjct: 278 TPSS---TTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQ 334

Query: 116 --TATLGNLRGYGMASPGLAAPS----LTPP-QLATPNLQQFFPQATRQSLLGPPPVGVP 168
               TL     + +  P  A P+    + PP ++  P +    P      ++  P V   
Sbjct: 335 PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTV 394

Query: 169 MNPSQFNLSGR--------NPQKQARTSSSTTPNRKTMPVEDKSDPPEG-----SEEAAE 215
                  L G         +PQ     S +T      +    +    +G     +    E
Sbjct: 395 ATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLE 454

Query: 216 PRMDTPED-QDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEK 266
              + P++ ++     E I +  + P+ EP P E       E P K ++     EE TE+
Sbjct: 455 STWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEE 514

Query: 267 EPPGQLQVKAQPQARMTVP 285
           E   Q   KA+P A   +P
Sbjct: 515 EKAAQ---KAKPVATAPIP 530


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 49/157 (31%), Positives = 73/157 (46%), Gaps = 11/157 (7%)

Query: 277  QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 335
            Q Q++++   Q      LP A  + V P   QP+  Q  AQ Q QTQP+ P+     QP+
Sbjct: 2364 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2418

Query: 336  LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--KQVQPQVHTQAQPSVQPQEHPPAQVS 393
            +Q Q + QT          + QP   Q ++PQ   Q QPQ + Q Q  V+ Q   P+Q  
Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQS--PSQTR 2476

Query: 394  VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 430
            ++P   +   P  Q QV     +  P+  H   L++P
Sbjct: 2477 IRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2512



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 67/271 (24%), Positives = 100/271 (36%), Gaps = 41/271 (15%)

Query: 153  QATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQAR--------TSSSTTPNRKTMPVEDKS 204
            Q T Q  L P  V V   P Q  +    P    +        T+++T     T      +
Sbjct: 2300 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAA 2359

Query: 205  DPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPT 264
               E  +    P+M   +D+ LPP                 P EA    A+     +  T
Sbjct: 2360 GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG----------PAEAQPQTAQPSAQPQPQT 2409

Query: 265  EKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL---QVQAQVQSQT 321
            + + P Q +V+ QP+    V  QT     +P   +       +P+V    Q Q+ VQ Q+
Sbjct: 2410 QPQSPAQPEVQTQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQS 2465

Query: 322  QPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPS 381
              R+ S     Q +++    +Q SP     QQ QVQ    Q    Q     Q+ +Q QP 
Sbjct: 2466 PVRVQSPS---QTRIRPSTPSQLSPG----QQSQVQTTTSQPIPIQPHTSLQIPSQGQPQ 2518

Query: 382  VQPQ---------EHPPAQVSVQPPEQTHEQ 403
             QPQ         EH   + S+ P E+   Q
Sbjct: 2519 SQPQVVMKHNAVIEHLKQKKSMTPAEREENQ 2549



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 40/143 (27%), Positives = 50/143 (34%), Gaps = 8/143 (5%)

Query: 270  GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 329
            GQLQ+  Q    +  P Q     L+  A+    + RF    L   A   S T   + +T 
Sbjct: 2303 GQLQLIPQGVTVLPGPGQ----QLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTA 2358

Query: 330  T----QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQ 385
                 Q Q KL  Q Q          Q   V P   Q    Q   QPQ  TQ Q   QP+
Sbjct: 2359 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2418

Query: 386  EHPPAQVSVQPPEQTHEQPHTQP 408
                 +V  Q    +H     QP
Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQP 2441



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%)

Query: 648 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 700
           + D   E +  E+++  ++E+           +GD EE +D ED+EE E+EE+
Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169



 Score = 30.0 bits (66), Expect = 9.3
 Identities = 17/60 (28%), Positives = 26/60 (43%)

Query: 227 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 286
           P  P   A E+  PAP P P   +  P   LRS    + +      Q +  P+ R++ P+
Sbjct: 9   PKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPR 68


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
           QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ P +             QQ 
Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 206

Query: 65  QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113
           QQ L   Q      LL    LQ+   LL  Q QGL      Q A+P  +   AGL+
Sbjct: 207 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 262



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 20/159 (12%)

Query: 260 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQ 318
           S + ++K+ P Q+ V     A MT   Q  TP  + + L+ QVL P+    +LQ Q  V 
Sbjct: 75  SPKSSDKQRPLQVPVSV---AMMT--PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVM 129

Query: 319 SQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQA 378
            Q Q        Q+Q   +KQ       E L LQ  Q Q Q QQ+ + Q+Q Q Q   Q 
Sbjct: 130 LQQQ--------QLQEFYKKQQ------EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175

Query: 379 QPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQ 417
           Q   Q Q+    Q    P +Q  EQ   Q Q   LA +Q
Sbjct: 176 QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%)

Query: 5   QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
           QQQQ +  QQQQLQ+    QQ+QL  Q LQQQQ  Q QQ  QQ   Q        +    
Sbjct: 123 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 182

Query: 62  QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121
           QQ QQ      G  +         Q+ L  QQL    Q            L        +
Sbjct: 183 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 235

Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155
           L+  G+ S  PG AA    SL    L+   +QQ + + T
Sbjct: 236 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 274



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 37/136 (27%), Positives = 54/136 (39%), Gaps = 3/136 (2%)

Query: 273 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQV---QAQVQSQTQPRIPSTD 329
           QV    Q +  + +Q  +P  L   L+ Q     Q + LQ    + Q Q   Q       
Sbjct: 97  QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 156

Query: 330 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPP 389
            Q Q + Q+Q Q Q   +    QQ+Q Q Q QQ+  P KQ + Q   Q Q      +   
Sbjct: 157 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 216

Query: 390 AQVSVQPPEQTHEQPH 405
            Q  +   +Q  +Q H
Sbjct: 217 FQQQLLQMQQLQQQQH 232



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 12/126 (9%)

Query: 296 EALEA--QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 353
           +AL+A  Q+L + Q   L+       Q   ++P +   + P++    Q Q   +  VL  
Sbjct: 56  QALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSP 115

Query: 354 KQVQPQLQQE----------AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQ 403
           +Q+Q  LQQ+           E  K+ Q Q+H Q     Q Q+    Q   Q  +Q  +Q
Sbjct: 116 QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175

Query: 404 PHTQPQ 409
              Q Q
Sbjct: 176 QQQQQQ 181



 Score = 33.5 bits (75), Expect = 0.84
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 12  QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAV--SRGLPPQQPQQPLL 69
           QQQQ LQ  +Q  LQQQ      L   +   +Q P Q P+ +A+   + + PQQ QQ +L
Sbjct: 53  QQQQALQAARQLLLQQQT---SGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQ-IL 108

Query: 70  NLQGTNSASLLNGSMLQRALLLQQLQ 95
             Q  +   L      Q+A++LQQ Q
Sbjct: 109 QQQVLSPQQLQALLQQQQAVMLQQQQ 134



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58
           QQ QQ LQQQ    QQLQ        LQQQQ +     QLQ+  ++   Q  L +   + 
Sbjct: 102 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155

Query: 59  LPPQQPQQ 66
              QQ QQ
Sbjct: 156 QQQQQQQQ 163


>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
          Length = 623

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
           QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ P +             QQ 
Sbjct: 60  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 114

Query: 65  QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113
           QQ L   Q      LL    LQ+   LL  Q QGL      Q A+P  +   AGL+
Sbjct: 115 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 170



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 45/132 (34%), Positives = 58/132 (43%), Gaps = 15/132 (11%)

Query: 287 QTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS 345
           Q  TP  + + L+ QVL P+    +LQ Q  V  Q Q        Q+Q   +KQ      
Sbjct: 5   QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQ--------QLQEFYKKQQ----- 51

Query: 346 PEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 405
            E L LQ  Q Q Q QQ+ + Q+Q Q Q   Q Q   Q Q+    Q    P +Q  EQ  
Sbjct: 52  -EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 110

Query: 406 TQPQVSLLAPEQ 417
            Q Q   LA +Q
Sbjct: 111 QQQQQQQLAAQQ 122



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%)

Query: 5   QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
           QQQQ +  QQQQLQ+    QQ+QL  Q LQQQQ  Q QQ  QQ   Q        +    
Sbjct: 31  QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 90

Query: 62  QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121
           QQ QQ      G  +         Q+ L  QQL    Q            L        +
Sbjct: 91  QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 143

Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155
           L+  G+ S  PG AA    SL    L+   +QQ + + T
Sbjct: 144 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 182



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 34/241 (14%)

Query: 273 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 332
           QV    Q +  + +Q  +P  L   L+ Q     Q + LQ   +   + Q ++     Q 
Sbjct: 5   QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ---EFYKKQQEQLHLQLLQQ 61

Query: 333 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 392
           Q + Q+Q Q Q   +    QQ+Q Q Q QQ+ + Q+Q  P    + Q   Q Q+   A  
Sbjct: 62  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 121

Query: 393 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQV 452
            +   +Q  +    Q Q  LL+ ++  ++       +PP         +  LP       
Sbjct: 122 QLVFQQQLLQMQQLQQQQHLLSLQRQGLI------SIPPG--------QAALP------- 160

Query: 453 SMEEIQNESACGLDVGECENRAREMPGVWG------AGGSLKVTILQSSDSRAFSTVPLT 506
               +Q+    GL   E +   +E+ GV          G L +T   SS + + +T   +
Sbjct: 161 ----VQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKAS 216

Query: 507 P 507
           P
Sbjct: 217 P 217



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%)

Query: 269 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 320
           P QLQ   Q Q  + + +Q        Q   L  + L+ Q   + Q +  Q Q Q  Q Q
Sbjct: 23  PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 82

Query: 321 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 380
            Q        Q Q + Q+Q Q Q  P     +Q+Q Q Q QQ A  Q   Q Q+    Q 
Sbjct: 83  QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ- 134

Query: 381 SVQPQEH-----PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 435
            +Q Q+H         +S+ PP Q      + PQ  L   E   +   V G+    D   
Sbjct: 135 -LQQQQHLLSLQRQGLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGI 192

Query: 436 AGGGMEKT 443
             GG++ T
Sbjct: 193 KHGGLDLT 200



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%)

Query: 4  QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58
          QQ QQ LQQQ    QQLQ        LQQQQ +     QLQ+  ++   Q  L +   + 
Sbjct: 10 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 63

Query: 59 LPPQQPQQ 66
             QQ QQ
Sbjct: 64 QQQQQQQQ 71


>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
          Length = 740

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
           QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ P +             QQ 
Sbjct: 177 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 231

Query: 65  QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113
           QQ L   Q      LL    LQ+   LL  Q QGL      Q A+P  +   AGL+
Sbjct: 232 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 287



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 47/143 (32%), Positives = 62/143 (43%), Gaps = 15/143 (10%)

Query: 276 AQPQARMTVPKQTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 334
           A P +   +  Q  TP  + + L+ QVL P+    +LQ Q  V  Q Q        Q+Q 
Sbjct: 111 AVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQ--------QLQE 162

Query: 335 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSV 394
             +KQ       E L LQ  Q Q Q QQ+ + Q+Q Q Q   Q Q   Q Q+    Q   
Sbjct: 163 FYKKQQ------EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 216

Query: 395 QPPEQTHEQPHTQPQVSLLAPEQ 417
            P +Q  EQ   Q Q   LA +Q
Sbjct: 217 HPGKQAKEQQQQQQQQQQLAAQQ 239



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%)

Query: 5   QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
           QQQQ +  QQQQLQ+    QQ+QL  Q LQQQQ  Q QQ  QQ   Q        +    
Sbjct: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 207

Query: 62  QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121
           QQ QQ      G  +         Q+ L  QQL    Q            L        +
Sbjct: 208 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 260

Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155
           L+  G+ S  PG AA    SL    L+   +QQ + + T
Sbjct: 261 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 299



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 34/241 (14%)

Query: 273 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 332
           QV    Q +  + +Q  +P  L   L+ Q     Q + LQ   +   + Q ++     Q 
Sbjct: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ---EFYKKQQEQLHLQLLQQ 178

Query: 333 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 392
           Q + Q+Q Q Q   +    QQ+Q Q Q QQ+ + Q+Q  P    + Q   Q Q+   A  
Sbjct: 179 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 238

Query: 393 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQV 452
            +   +Q  +    Q Q  LL+ ++  ++       +PP         +  LP       
Sbjct: 239 QLVFQQQLLQMQQLQQQQHLLSLQRQGLI------SIPPG--------QAALP------- 277

Query: 453 SMEEIQNESACGLDVGECENRAREMPGVWG------AGGSLKVTILQSSDSRAFSTVPLT 506
               +Q+    GL   E +   +E+ GV          G L +T   SS + + +T   +
Sbjct: 278 ----VQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKAS 333

Query: 507 P 507
           P
Sbjct: 334 P 334



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%)

Query: 269 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 320
           P QLQ   Q Q  + + +Q        Q   L  + L+ Q   + Q +  Q Q Q  Q Q
Sbjct: 140 PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 199

Query: 321 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 380
            Q        Q Q + Q+Q Q Q  P     +Q+Q Q Q QQ A  Q   Q Q+    Q 
Sbjct: 200 QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ- 251

Query: 381 SVQPQEH-----PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 435
            +Q Q+H         +S+ PP Q      + PQ  L   E   +   V G+    D   
Sbjct: 252 -LQQQQHLLSLQRQGLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGI 309

Query: 436 AGGGMEKT 443
             GG++ T
Sbjct: 310 KHGGLDLT 317



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58
           QQ QQ LQQQ    QQLQ        LQQQQ +     QLQ+  ++   Q  L +   + 
Sbjct: 127 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180

Query: 59  LPPQQPQQ 66
              QQ QQ
Sbjct: 181 QQQQQQQQ 188


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 86/321 (26%), Positives = 120/321 (37%), Gaps = 44/321 (13%)

Query: 130  PGLAAPSL---TPPQLAT----PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 182
            PGL +PSL   TP   A     PNL    P  T  S  G P  G+P  PS  +LS   P 
Sbjct: 3127 PGLNSPSLPGFTPSNTALTSPKPNLMGL-PSTTVPSP-GLPTSGLPNKPSSASLSSPTPA 3184

Query: 183  KQARTSSSTTP----NRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKR 238
            +         P     ++  P   +  PP  ++    P++   + Q       +  KEK 
Sbjct: 3185 QATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKE 3244

Query: 239  ---------TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ 289
                      P P+ E  EA    A  + S+  PT +      Q++A   A  + P    
Sbjct: 3245 KAHKGKGEPLPVPKKEKGEAPTATAATI-SAPLPTMEYAVDPAQLQALQAALTSDPTALL 3303

Query: 290  TPDLLPEALEAQVLPRFQPRVL-QVQAQVQS-QTQPRIPSTDTQVQPKLQKQAQTQTSPE 347
            T   LP       +P F P    Q+   +QS   QP               QA    SP 
Sbjct: 3304 TSQFLP-----YFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPG 3358

Query: 348  HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP----------- 396
             L+ Q +Q Q  LQ+    Q+Q Q Q+  Q Q  VQ Q+   +Q  V P           
Sbjct: 3359 SLLQQYQQYQQSLQEAI--QQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAK 3416

Query: 397  -PEQTHEQPHTQPQVSLLAPE 416
               +  EQ +T  +VS L P+
Sbjct: 3417 ESPKPEEQKNTPREVSPLLPK 3437



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 109/441 (24%), Positives = 150/441 (34%), Gaps = 56/441 (12%)

Query: 3    SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
            S+QQQQQ QQQQQQ QQ QQQ     Q Q Q    LQQ LQQ                  
Sbjct: 1721 SRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQ------------------ 1762

Query: 63   QPQQPLLNLQGTNSASLLNGSMLQRALL-LQQLQG-LDQFAMPPATYDTAGLTMPTATLG 120
              Q  L+  Q  N   L +  M    LL LQQ Q  L  F +P A +          T G
Sbjct: 1763 --QAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSG 1820

Query: 121  NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
             L   G   PGL        Q+   + QQ  PQ  +  L         + PSQ      +
Sbjct: 1821 ALTLTG-TGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQ------H 1873

Query: 181  PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240
            P+K+    +      K    + + D  EG E    P+      + LP   +   K++  P
Sbjct: 1874 PEKK----NKLVIKEKEKESQRERDSAEGGEGNTGPK------ETLPDALKAKEKKELAP 1923

Query: 241  APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP--EAL 298
                EP       A   R +      E  G   V    + +  V K+    D     E L
Sbjct: 1924 GGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGENLEKL 1983

Query: 299  EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 358
            E     +    +L +++  +   Q   P    +   K  +    +  P         ++P
Sbjct: 1984 ECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYP---------LRP 2034

Query: 359  QLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP---PEQTHEQPHTQPQVSLLAP 415
            Q  +   P     P     A P  QP   P    S  P   P     QP + P   L  P
Sbjct: 2035 QTPEPPPPPPPPPPPPLPAAPP--QPASTPAIPASAPPITSPTIAPAQP-SVPLTQLSMP 2091

Query: 416  EQTPVVVHVCGLEMPPDAVEA 436
             + P+   +    MP   + A
Sbjct: 2092 MELPIFSPLMMQTMPLQTLPA 2112



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 25/218 (11%)

Query: 534  CYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRR 593
            C +C+ +   +  FQ H    +H Q+   + H+ +    +   +    +       P   
Sbjct: 986  CKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGN-----PVHL 1040

Query: 594  WCNTCQLY---------------YMGDLIQHRRTQDHK--IAKQSLRPFCTVCNRYFKTP 636
             CN C  Y               +   L  ++  Q H+  +  +S    C +CN   K  
Sbjct: 1041 KCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAK 1100

Query: 637  RKFVEHVKSQGHK--DKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEE-EDDEDEE 693
               ++HV+S  H+  +  ++L+ L+K +  +DED         C   D EE  ED E   
Sbjct: 1101 LNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPS 1160

Query: 694  EIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDF 731
            E   + E   + +    S  + +   T SP T+  + F
Sbjct: 1161 ETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISF 1198



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 24/49 (48%), Positives = 29/49 (59%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLP 52
            QQ QQ  Q  Q+ +QQ QQ+QLQQQQ Q+ Q  Q +      PP AP P
Sbjct: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP 3410



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 22/55 (40%), Positives = 30/55 (54%)

Query: 10   LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
            L QQ QQ QQ  Q+ +QQQQ +Q Q  Q Q++ QQ P  +  P+      P + P
Sbjct: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDP 3414



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 80/367 (21%), Positives = 137/367 (37%), Gaps = 58/367 (15%)

Query: 311  LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--- 367
            LQ+ A+ +        +     +PKL +    Q  P     +Q Q +P+LQQ+ +P+   
Sbjct: 2407 LQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQ--PNQTQEKQGQPKPELQQQEQPEQKT 2464

Query: 368  ---KQVQPQVHT-----QAQPSVQPQEHPPAQVSVQPPEQTH-----EQPHTQPQVSLLA 414
               +Q  PQ+ +     Q  P   P + P  Q S  P + +H         T  Q++ L 
Sbjct: 2465 NTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLP 2524

Query: 415  PEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 474
            P+  P     C L  P          E         Q+     QN+        +  +R+
Sbjct: 2525 PQLIPYQCDQCKLAFP--------SFEHWQEH---QQLHFLSAQNQ----FIHPQFLDRS 2569

Query: 475  REMP-GVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 533
             +MP  ++     L  + L S          +  +P  S +  STP +T    K+ L+  
Sbjct: 2570 LDMPFMLFDPSNPLLASQLLSG--------AIPQIPASSATSPSTPTSTMNTLKRKLEE- 2620

Query: 534  CYICKASCS-SQQEFQDHMSEPQHQQRL------GEIQHMSQACLLSLLPVPRDVLETED 586
                KAS S  + +      EPQ  +RL       +++ + Q  LL   P  R +L+   
Sbjct: 2621 ----KASASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPT-RKMLDHIA 2675

Query: 587  EEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQ 646
             E   ++     Q+++     + R+ Q   +        C  C   FK       H++S+
Sbjct: 2676 HEVGLKK--RVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSR 2733

Query: 647  GHKDKAK 653
             H  +AK
Sbjct: 2734 -HWHEAK 2739



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 7/86 (8%)

Query: 3    SQQQQQQLQQQQQQLQQLQQQQLQQQQLQ--QQQLLQLQQL--LQQSPPQAP---LPMAV 55
            S Q  Q  ++Q Q   +LQQQ+  +Q+    QQ+L QL  L  L Q PPQAP    P+  
Sbjct: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQ 2496

Query: 56   SRGLPPQQPQQPLLNLQGTNSASLLN 81
            S   P Q    PL  L  +    L N
Sbjct: 2497 SSPSPSQLSHLPLKPLHTSTPQQLAN 2522



 Score = 38.1 bits (87), Expect = 0.034
 Identities = 60/270 (22%), Positives = 99/270 (36%), Gaps = 32/270 (11%)

Query: 4    QQQQQQLQQQQQQLQ--------------QLQQQQLQQQQLQQQQLLQLQQLLQQSPPQA 49
            Q  QQQ QQQQ Q+Q              QL  QQ QQ++ +  + ++ ++   +   + 
Sbjct: 3194 QPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGE- 3252

Query: 50   PLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT 109
            PLP      +P ++  +       T SA L     ++ A+   QLQ L        T   
Sbjct: 3253 PLP------VPKKEKGEAPTATAATISAPL---PTMEYAVDPAQLQALQAALTSDPTALL 3303

Query: 110  AGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPM 169
                +P    G    Y    PG        P      L  + P A  Q+L+G  P  +  
Sbjct: 3304 TSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSP-ALSQALMGLSPGSLLQ 3362

Query: 170  NPSQFNLSGRNP-QKQARTSSSTTPNRKTMPVEDKSD----PPEGSEEAAEPRMDTPEDQ 224
               Q+  S +   Q+Q +        +K    + K+     PP       +P  ++P+ +
Sbjct: 3363 QYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPE 3422

Query: 225  DLPPCPEDIAK--EKRTPAPEPEPCEASEL 252
            +    P +++    K    PE E   A  L
Sbjct: 3423 EQKNTPREVSPLLPKLPEEPEAESKSADSL 3452



 Score = 33.9 bits (76), Expect = 0.64
 Identities = 18/50 (36%), Positives = 27/50 (54%)

Query: 334  PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ 383
            P   K+A  +   + +  +Q+Q Q Q QQ+ + Q+Q Q Q   QAQ  VQ
Sbjct: 1704 PSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQ 1753



 Score = 33.9 bits (76), Expect = 0.64
 Identities = 46/190 (24%), Positives = 71/190 (37%), Gaps = 37/190 (19%)

Query: 190  STTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP--------PCPEDIAKEKRTPA 241
            S  PN+ T   + +  P    +E  E + +TP+ Q LP        P P   A   + P 
Sbjct: 2437 SAQPNQ-TQEKQGQPKPELQQQEQPEQKTNTPQ-QKLPQLVSLPSLPQPPPQAPPPQCPL 2494

Query: 242  PE--PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP-------------- 285
            P+  P P + S LP K L +S        P QL      Q ++  P              
Sbjct: 2495 PQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFL 2554

Query: 286  ---KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI-------PSTDTQVQPK 335
                Q   P  L  +L+   +  F P    + +Q+ S   P+I       PST T     
Sbjct: 2555 SAQNQFIHPQFLDRSLDMPFM-LFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNT 2613

Query: 336  LQKQAQTQTS 345
            L+++ + + S
Sbjct: 2614 LKRKLEEKAS 2623



 Score = 33.5 bits (75), Expect = 0.84
 Identities = 15/34 (44%), Positives = 23/34 (67%)

Query: 680 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISRE 713
           E + EEEE++E+EEE E E+E CK +   ++  E
Sbjct: 469 EEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 6/73 (8%)

Query: 313  VQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQP 372
            + A + S ++P+  +          +Q Q Q        QQ+Q Q Q QQ+A+   Q Q 
Sbjct: 1697 IGANIASPSEPKEANRKKLADMIASRQQQQQQQ------QQQQQQQQQQQQAQTLAQAQA 1750

Query: 373  QVHTQAQPSVQPQ 385
            QV    Q  +Q Q
Sbjct: 1751 QVQAHLQQELQQQ 1763



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 9/54 (16%)

Query: 656 KSLEKEIAGQDEDHFITVDAVGCF---------EGDEEEEEDDEDEEEIEVEEE 700
           KS E + +G  E     V    CF         E +EEEEE++ +EEE E EEE
Sbjct: 429 KSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEE 482



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 14/21 (66%), Positives = 17/21 (80%)

Query: 680 EGDEEEEEDDEDEEEIEVEEE 700
           E +EEEEE +E+EEE E EEE
Sbjct: 464 EEEEEEEEAEEEEEEEEEEEE 484


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 67/296 (22%), Positives = 110/296 (37%), Gaps = 32/296 (10%)

Query: 162 PPPVGVPMNPSQFNLSGRNPQKQAR---------TSSSTTPNRKTMPVEDKSDPPEGSEE 212
           PP V   +   Q  L    P+++AR         T +   P     P+  ++   E S E
Sbjct: 414 PPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAE 473

Query: 213 -----AAEPRMD-TPEDQDLPPCPEDIAKEK----RTPAPEPEPCEASELPAKRLRSSEE 262
                A EP  D TP +   P   E  A+E     ++P  E    E +    + L + E 
Sbjct: 474 IQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEA 533

Query: 263 PTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA------- 315
           P ++ P       ++  +    P + Q+P     ++E   L    P   +  A       
Sbjct: 534 PADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAI 593

Query: 316 QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVH 375
           Q+ + T+        +VQP   ++A  +  P        +VQP   +EA  + Q  P   
Sbjct: 594 QLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEE 653

Query: 376 TQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 431
             A+    P E  PA+V   P E+         +V  L  E+TP+   +  +  PP
Sbjct: 654 APAEVQPPPAEEAPAEVQPPPAEE------APAEVQSLPAEETPIEETLAAVHSPP 703



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 80/392 (20%), Positives = 144/392 (36%), Gaps = 55/392 (14%)

Query: 183 KQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 242
           K+  ++    P+ +  P + +    E +   AEPR        + P  E+    +   A 
Sbjct: 250 KKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAV 309

Query: 243 EPEPCEASELPAKRLRSSEEPTEKEPPG-------QLQVKAQPQARMTVPKQTQTPDLLP 295
                +    PA+     E P E +PP        +L  +  P +    P +    ++LP
Sbjct: 310 AENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILP 369

Query: 296 EALE----AQVL-----PRFQPRVLQVQ------------AQVQSQTQPRIPSTDTQVQP 334
              E     ++L     P  Q   ++VQ            A+V+    P +  T   VQP
Sbjct: 370 PPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVE---PPTVEETLADVQP 426

Query: 335 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ---------PQ 385
            L ++A  + + E L L      P  +   E Q  + P+  T  + S +         P 
Sbjct: 427 LLPEEAPREEARE-LQLSTAMETPAEEAPTEFQSPL-PKETTAEEASAEIQLLAATEPPA 484

Query: 386 EHPPAQVSVQPPEQTH-EQPHTQPQVSL----LAPEQTPVVVHVCGLEMPPDAVEAGGGM 440
           +  PA+      E+T  E+ H + Q  L     A E +  +  +  +E P D  E     
Sbjct: 485 DETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPAD--ETPAEA 542

Query: 441 EKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG--VWGAGGSLKVTILQSSDSR 498
           +  L E    + +  E+Q+ SA G+ + E     +   G        S  + +L ++++ 
Sbjct: 543 QSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEAS 602

Query: 499 AFSTVPLTPVPRPSDSVSS---TPAATSTPSK 527
           A    P    P P++   +    P A   P++
Sbjct: 603 A-EEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 633



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 45/207 (21%), Positives = 73/207 (35%), Gaps = 25/207 (12%)

Query: 192 TPNRKTMPVED---KSDPPEGSEEAAEPRM--------------DTPEDQDLPPCPEDIA 234
           +P+ K + +E+   +  PP G E  AE                 + P +   PP  E+  
Sbjct: 561 SPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPA-EEAP 619

Query: 235 KEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPG--QLQVKAQPQARMTVPKQTQTPD 292
            E + P  E  P E    PA+     E P E +PP   +   + QP      P + Q P 
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAE-----EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPP 674

Query: 293 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 352
                 E Q LP  +  + +  A V S     +P+ +  V           T    +   
Sbjct: 675 AEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEA 734

Query: 353 QKQVQPQLQQEAEPQKQVQPQVHTQAQ 379
             +V P   ++    + +   V T+ Q
Sbjct: 735 SAEVSPPPSEQTPEDEALVENVSTEFQ 761



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 69/328 (21%), Positives = 126/328 (38%), Gaps = 57/328 (17%)

Query: 183 KQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPE---DQDLPPC---------- 229
           K  +T +     ++   VE+   P E S +  E  ++ PE   D ++PP           
Sbjct: 71  KSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDR 130

Query: 230 -----------------PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL 272
                             E + KE++T   E E    S   +   +S E+  + +  G++
Sbjct: 131 SQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKI 190

Query: 273 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 332
                P+ +   P      ++  + +      +   +   V  + + + +  +P    Q 
Sbjct: 191 FASEHPEFQ---PATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVV--QE 245

Query: 333 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQP--QVHTQAQPSVQPQEHPPA 390
              ++K A  +  P        ++QP L +EA  + + +P  + H Q QPS   +E P A
Sbjct: 246 GSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPST--EETPDA 303

Query: 391 Q---------VSVQPPEQTHEQPHTQPQVSLLAP--EQTPVVVHVCGLEMPPDAVEAGG- 438
           +         V VQPP    E P  +    +  P  E++P V  +  + +PP A E+   
Sbjct: 304 EAATAVAENSVKVQPP-PAEEAPLVEFPAEIQPPSAEESPSVELLAEI-LPPSAEESPSE 361

Query: 439 -GMEKTLPEPVGTQVSME---EIQNESA 462
               + LP P     S+E   EI++ SA
Sbjct: 362 EPPAEILPPPAEKSPSVELLGEIRSPSA 389



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 42/163 (25%), Positives = 59/163 (36%), Gaps = 33/163 (20%)

Query: 181 PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAE----PRMDTPEDQDLPPCPEDIAKE 236
           P  +   +    P  +  P E +  PP   E  AE    P  + P +   PP  E+   E
Sbjct: 613 PPAEEAPAEVQPPPAEEAPAEVQ--PPPAEEAPAEVQPPPAEEAPAEVQPPPA-EEAPAE 669

Query: 237 KRTPAPEPEPCEASELPAKRLRSSEE------------PTEK------EPPGQLQVK--- 275
            + P  E  P E   LPA+     E             P E+       PP  L +    
Sbjct: 670 VQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEF 729

Query: 276 --AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ-PRVLQVQA 315
              +  A ++ P   QTP+   EAL   V   FQ P+V  + A
Sbjct: 730 PIGEASAEVSPPPSEQTPE--DEALVENVSTEFQSPQVAGIPA 770


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 83/365 (22%), Positives = 136/365 (37%), Gaps = 76/365 (20%)

Query: 130   PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR---------- 179
             P    P + PP+   P  +   P A +      PP  VP  P +     +          
Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKPEA---PPPKVPEAPKEVVPEKKVPVPPPKKPE 10547

Query: 180   -NPQKQARTSSSTTPNRKT---MPVEDKSDPPEGSEE-----------AAEPRMDTPEDQ 224
               P K      +  P +K    +P + +S PPE  E            AA P+       
Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPV 10607

Query: 225   DLPPCPEDIAKEKRTPAPEPE-----PCEASELPAKRLRSS------------------E 261
              +P  P+++  EK+ P P P+     P +  E+P   +                     E
Sbjct: 10608 KVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFE 10667

Query: 262   EPTE---KEPPGQLQVKAQPQA--RMTVPKQTQTPDLLPEALEAQVLPRFQP-RVLQVQA 315
             EP E   +EPP ++  + +P A  ++TVP +   P+    A+ A+  P   P +V +V  
Sbjct: 10668 EPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAK-KPELPPVKVPEVPK 10726

Query: 316   QVQSQTQ-----PRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQV 370
             +V  + +     P+ P       P++ K+          V+ +K+V    + E  P K  
Sbjct: 10727 EVVPEKKVPLVVPKKPEAPPAKVPEVPKE----------VVPEKKVAVPKKPEVPPAK-- 10774

Query: 371   QPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV-VVHVCGLEM 429
              P+V  +     +P    P +    PPE   E     P+  +   E+ PV V      E+
Sbjct: 10775 VPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEV 10834

Query: 430   PPDAV 434
             PP AV
Sbjct: 10835 PPPAV 10839



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 73/324 (22%), Positives = 132/324 (40%), Gaps = 58/324 (17%)

Query: 163   PPVGVPMNPSQFNLSGRNPQKQART--SSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDT 220
             PP  VP  P       + P+++          P    +P   K   PE       P+   
Sbjct: 9974  PPAKVPEVP-------KKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVE 10026

Query: 221   PEDQDLPPCPEDIAKEKRTPAPEPE-----PCEASELPAKRLRSSEEPTE-----KEPPG 270
                  +P  P+    EK+ P P P+     P +  E+P K +   ++PT      + PP 
Sbjct: 10027 APPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPP 10086

Query: 271   QLQVKAQP-QARMTVPKQTQT---------PDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 320
             ++  K +P    + +P++ +           ++LPE  E +VLP  +  VL  + +V  +
Sbjct: 10087 KVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPE--EEEVLPE-EEEVLPEEEEVLPE 10143

Query: 321   TQPRIPSTDTQVQPKLQ-KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 379
              +  IP  + +V P+ +    + +  PE  VL   +V+P++   A P  +++ +V  +  
Sbjct: 10144 -EEEIPPEEEEVPPEEEYVPEEEEFVPEEEVL--PEVKPKVPVPA-PVPEIKKKVTEKKV 10199

Query: 380   PSVQPQEHPPAQVSVQP-----------------PEQTHEQPHTQPQVSLLAPEQTPVVV 422
                + +E PPA+V   P                 P +  E+P  +P      PE+ P + 
Sbjct: 10200 VIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIE 10259

Query: 423   HVCGLEMPPDAVEAGGGMEKTLPE 446
              V  +  PP   E    ++K +PE
Sbjct: 10260 EVEEV-APPRVPEV---IKKAVPE 10279



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 57/210 (27%), Positives = 85/210 (40%), Gaps = 14/210 (6%)

Query: 241   APEPEPCEASELPAKRLRSSEEPTE-KEPPGQLQVKAQPQARMT-VPKQTQTPDLLPEAL 298
             A E E  E  + P K    SE+    K+PP ++  + +P A++  VPK+    + +    
Sbjct: 10427 AEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPE 10486

Query: 299   EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 358
             E +V P   P VL  +  V  +  P  P+   +  P    +A  +  PE  V     V P
Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKV----PVPP 10542

Query: 359   QLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL-LAPEQ 417
               + E  P K   P+V   A P  +  E  P +    PPE         P+  +  AP +
Sbjct: 10543 PKKPEVPPTK--VPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPK 10600

Query: 418   TPVVVHVCGLEMPPDAVEAGGGMEKTLPEP 447
              P V  V   E P + V      EK +P P
Sbjct: 10601 KPEVTPVKVPEAPKEVVP-----EKKVPVP 10625



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 72/325 (22%), Positives = 128/325 (39%), Gaps = 41/325 (12%)

Query: 129   SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGP-----PPVGVPMNPSQFNLSGRNP-Q 182
             +P + A     P +  P + +      +  L+ P     PP  VP  P +     +    
Sbjct: 10706 APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765

Query: 183   KQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 242
             K+     +  P     PV ++       E A  P  +  E+ +     E+IA E+  P P
Sbjct: 10766 KKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVP 10825

Query: 243   -----EPE--PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTP---- 291
                  EPE  P    E P K +   + P  K+P      + +P+  +  PK    P    
Sbjct: 10826 VAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPP 10885

Query: 292   ------DLLPEALEAQVLPRFQ-PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 344
                   D+  +  + + +P+ + P   QV  +V+  T  ++P  + +V+ KL  + + + 
Sbjct: 10886 PAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVE-LTPLKVPGGEKKVR-KLLPERKPEP 10943

Query: 345   SPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV-SVQPPEQTHEQ 403
               E ++   K V  +  +E EP  +V+P+   + +    P+  PP  V  V+ P  T  +
Sbjct: 10944 KEEVVL---KSVLRKRPEEEEP--KVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE 10998

Query: 404   ---------PHTQPQVSLLAPEQTP 419
                      P  +P + L APE  P
Sbjct: 10999 RKIPEPTKVPEIKPAIPLPAPEPKP 11023



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 70/300 (23%), Positives = 117/300 (39%), Gaps = 69/300 (23%)

Query: 193   PNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQD--LPPCPEDIAKEKRTPAP-EPEPCEA 249
             P  +  P E+K  P    EE   P    PE+    +P     + K+   P P EPEP + 
Sbjct: 10812 PEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKV 10871

Query: 250   SELPAKRLRSSEEPTEKEPPGQ------LQVKAQPQARMTVPKQTQTPDLL--------- 294
              E P  +L+    P    PP +       Q+KA P+ +  VP++ Q P+ +         
Sbjct: 10872 IEKP--KLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKK--VPEKPQVPEKVELTPLKVPG 10927

Query: 295   -------------PEALEAQVL------------PRFQPRVLQ-VQAQVQSQTQPRIPST 328
                          PE  E  VL            P+ +P+ L+ V+     +  P  P  
Sbjct: 10928 GEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVE 10987

Query: 329   DTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA-EPQKQVQPQVHTQAQPSVQPQEH 387
             + +V P + K+ +    P  +     +++P +   A EP+ + + +V T   P V+P+  
Sbjct: 10988 EVEV-PTVTKRERKIPEPTKV----PEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPT 11042

Query: 388   P---PAQVSVQPPEQTHEQPH---TQPQVSLL-APEQTPVVVHV--------CGLEMPPD 432
             P   P  V V   +   + P     +P+  +   P++TP  +           G E PPD
Sbjct: 11043 PIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPD 11102



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 71/316 (22%), Positives = 125/316 (39%), Gaps = 60/316 (18%)

Query: 181   PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK----- 235
             P K           R  +P E++  P E +EE  E  +   E  + PP  E++ +     
Sbjct: 10209 PAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPR 10268

Query: 236   -----EKRTP-APEPEPCEASELPAKRLRSSEE-----PTEKE--PPGQLQ--VKAQPQA 280
                  +K  P AP P P +    PAK  +   E     P +K+  PP ++    K  P+ 
Sbjct: 10269 VPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEK 10328

Query: 281   RMTVPKQTQTPDLLPE-ALEAQVLPRFQPRVL---QVQAQVQSQTQPRIPSTDT--QVQP 334
             ++ VPK+   P       LE +V   F+  V+   +++ +V       IP  +   +V+ 
Sbjct: 10329 KVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEE 10388

Query: 335   KLQ-----------KQAQTQTSPEHL---------VLQQKQVQPQLQQEAEPQ-KQVQPQ 373
               +           K  Q +   EH          V + ++V+   + +A P+  ++  +
Sbjct: 10389 YFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEK 10448

Query: 374   VHTQAQP--SVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 431
             +    +P   V P++ PPA+V   P +   E+    P+   + P + P V       +PP
Sbjct: 10449 IIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEV-------LPP 10501

Query: 432   DAVEAGGGMEKTLPEP 447
               V      EK +P P
Sbjct: 10502 KEVVP----EKKVPVP 10513



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 45/262 (17%), Positives = 105/262 (40%), Gaps = 34/262 (12%)

Query: 217  RMDTPEDQDLPPCPEDIAKEKRTPAPEP---------------EPCEASELPAKRLRSSE 261
            +++ P    +P  P+ I  EK+ PAP P               +P    ++P K ++  E
Sbjct: 9571 KIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEE 9630

Query: 262  EPTEKEPPGQLQVKAQPQARMTVPKQTQTPD---------LLPEALEAQVLPRFQ----P 308
                K     +Q+  + +  + V K+   P           +PE    ++ P+ +     
Sbjct: 9631 PLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPA 9690

Query: 309  RVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQK 368
            +V + + +V  + +  I +   + QP +++    +       L+++ V  Q ++E E  +
Sbjct: 9691 KVTEFRKRVVKEEKVSIEAPKREPQP-IKEVTIMEEKERAYTLEEEAVSVQREEEYEEYE 9749

Query: 369  QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQ--VSLLAPEQTPVVVHVCG 426
            +   +   + +P+ +  ++   +       + HE+  T+P+  + +    + PV      
Sbjct: 9750 EYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKP-- 9807

Query: 427  LEMPPDAVEAGGGMEKTLPEPV 448
             + PP  V      E+ +P P+
Sbjct: 9808 -KAPPAKVLKKAVPEEKVPVPI 9828



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 53/265 (20%), Positives = 101/265 (38%), Gaps = 23/265 (8%)

Query: 198  MPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE----PCEASELP 253
            +P+  K +PP   +    P+   PE++   P P+   KE   P   PE    P    ++P
Sbjct: 9303 VPIPKKVEPP-APKVPEVPKKPVPEEKKPVPVPK---KEPAAPPKVPEVPKKPVPEEKIP 9358

Query: 254  AKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV------LPRFQ 307
                +  E P  K P  Q  V  + +  +   ++   P  +PE  + +V      +PR +
Sbjct: 9359 VPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKE 9418

Query: 308  PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA---QTQTSPEHLVLQQKQVQPQLQQEA 364
              V     +V +  +  +P     V   + K+A   + + S + +V +++ V  +    A
Sbjct: 9419 EEV-PPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFA 9477

Query: 365  EPQKQVQPQVHTQAQPS-VQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVV- 422
             PQ+    +    A+      +E     +SV   E+  E+   +     +  E    VV 
Sbjct: 9478 VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVE 9537

Query: 423  ---HVCGLEMPPDAVEAGGGMEKTL 444
               H+    +  +  E     EK +
Sbjct: 9538 EKLHIISKRVEAEPAEVTERQEKKI 9562



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 61/271 (22%), Positives = 116/271 (42%), Gaps = 42/271 (15%)

Query: 192   TPNRKTMPVEDKSDPPEGSEEAAEP----RMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 247
             T   K +PV+   + P  ++  A P    +   PE++   P P+     K  P P   P 
Sbjct: 9787  TEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPK-----KLKPPPPKVPE 9841

Query: 248   EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTV-PKQTQTPDLLPEALEAQVLPRF 306
             E  ++  +++R S    EKE     QV  +P A++ + PK+    + +P       +PR 
Sbjct: 9842  EPKKVFEEKIRISITKREKE-----QV-TEPAAKVPMKPKRVVAEEKVP-------VPR- 9887

Query: 307   QPRVLQVQAQVQSQTQPRIPSTDTQVQPK-LQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 365
                  +V   V      R+P    +++P+ +  + +  T  E  ++++++     ++E  
Sbjct: 9888  ----KEVAPPV------RVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFI 9937

Query: 366   PQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVC 425
              +++V P +  +  P V  +  P  +  V  P++    P   P+V     E+ PV++   
Sbjct: 9938  TEEEVVPVIPVKV-PEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIP-- 9994

Query: 426   GLEMPPDA----VEAGGGMEKTLPEPVGTQV 452
               E PP A    V      E+ +P PV  +V
Sbjct: 9995  KKEKPPPAKVPEVPKKPVPEEKVPVPVPKKV 10025



 Score = 38.1 bits (87), Expect = 0.034
 Identities = 42/224 (18%), Positives = 92/224 (41%), Gaps = 20/224 (8%)

Query: 181  PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240
            P+ +AR+++      K + +E K  PP+      + R+  P        PE+I      P
Sbjct: 8911 PRGEARSTAELYLTTKEIKLELK--PPD----IPDSRVPIPTMPIRAVPPEEIPPVVAPP 8964

Query: 241  APEPEPC-EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALE 299
             P   P  E  + P KR+  +++  +K+    +    +   R  + K+   P  L     
Sbjct: 8965 IPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTL----- 9019

Query: 300  AQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 359
               +P   P ++ V ++ +      I       + ++QK+ +     +  V ++K+V  +
Sbjct: 9020 ---IPAKAPEIIDVSSKAEEVKIMTITR-----KKEVQKEKEAVYEKKQAVHKEKRVFIE 9071

Query: 360  LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQ 403
              +E   + +V+P      QP  +  +    ++ V+  ++ HE+
Sbjct: 9072 SFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEE 9115



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 66/340 (19%), Positives = 124/340 (36%), Gaps = 57/340 (16%)

Query: 208  EGSEEAAEPRMDTPEDQDLPPCPEDI---AKEKRTPAPEPE---PCEASELPAKRLRSSE 261
            EG +E  E   +  +++++    +++   + E++ PA  PE   P     +    +   E
Sbjct: 9131 EGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIE 9190

Query: 262  EPTEKEPPGQLQVKAQPQ-ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 320
            + + +    ++QV   P+ ++  VP++     +  E +E +V     P V   +  +  +
Sbjct: 9191 KTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKV-----PAVHTKKMVISEE 9245

Query: 321  TQPRIPSTDTQVQ---PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQ 377
                   T+ +V    P++QK+  T+      V   K+V+P  +    P+K    +V   
Sbjct: 9246 KMFFASHTEEEVSVTVPEVQKEIVTEEKIH--VAISKRVEPPPKVPELPEKPAPEEVAPV 9303

Query: 378  AQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAG 437
              P       P      + P    ++P   P+    AP + P        E+P   V   
Sbjct: 9304 PIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVP--------EVPKKPVP-- 9353

Query: 438  GGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDS 497
               E+ +P PV         + + A    V E +          G     K+TI+   + 
Sbjct: 9354 ---EEKIPVPVA--------KKKEAPPAKVPEVQK---------GVVTEEKITIVTQREE 9393

Query: 498  RAFSTVP----------LTPVPRPSDSVSSTPAATSTPSK 527
                 VP            PVPR  + V   P   + P K
Sbjct: 9394 SPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKK 9433



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 34/191 (17%), Positives = 77/191 (40%), Gaps = 7/191 (3%)

Query: 215  EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV 274
            EPR +     +L    ++I  E + P           +P + +   E P    PP  L +
Sbjct: 8910 EPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLL 8969

Query: 275  KAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 334
               P+ +   PK+ +      +    +V+ +  P+ +  + ++  +  P      T +  
Sbjct: 8970 PT-PEEKKPPPKRIEVTKKAVKKDAKKVVAK--PKEMTPREEIVKKPPP----PTTLIPA 9022

Query: 335  KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSV 394
            K  +     +  E + +     + ++Q+E E   + +  VH + +  ++  E P  ++ V
Sbjct: 9023 KAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEV 9082

Query: 395  QPPEQTHEQPH 405
            +P  +  EQP+
Sbjct: 9083 EPYTEPFEQPY 9093



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 57/279 (20%), Positives = 105/279 (37%), Gaps = 29/279 (10%)

Query: 129  SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 188
            SP  A P +  P+   P  ++  P+   +    PPP  VP  P       + P  + + +
Sbjct: 9394 SPPPAVPEI--PKKKVPEERKPVPRKEEEV---PPPPKVPALP-------KKPVPEEKVA 9441

Query: 189  SSTTPNRKTMPVE---DKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE 245
                  +K  P      K    E     AE ++     Q +     +++ E+     E E
Sbjct: 9442 VPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEE 9501

Query: 246  PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPR 305
              E   +   R    EE  E E   + +V  +P+    V ++        EA  A+V  R
Sbjct: 9502 --EGVSISVYREEEREEEEEAEVT-EYEVMEEPE-EYVVEEKLHIISKRVEAEPAEVTER 9557

Query: 306  FQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 365
             + +++          +P+IP+   +  P    +A  +  PE  V      + ++     
Sbjct: 9558 QEKKIV---------LKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKV 9608

Query: 366  PQKQVQPQVHTQAQPSVQPQEHP-PAQVSVQPPEQTHEQ 403
            P++  +P    +  P V   E P PA+V+ +  + T E+
Sbjct: 9609 PEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEE 9647



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 49/266 (18%), Positives = 104/266 (39%), Gaps = 20/266 (7%)

Query: 130   PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 189
             P +  P   PP+   P       +   +  L P P   P  P + ++  +  Q +A    
Sbjct: 10853 PVIKKPEAPPPKEPEPE------KVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKA-IPK 10905

Query: 190   STTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKE--KRTPAPEPEPC 247
                P +  +P + +  P +      + R   PE +  P   E + K   ++ P  E    
Sbjct: 10906 KKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPK-EEVVLKSVLRKRPEEEEPKV 10964

Query: 248   EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ 307
             E  +L   +  +  EP   +P  +++V    +    +P+ T+ P++ P    A  LP  +
Sbjct: 10965 EPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKP----AIPLPAPE 11020

Query: 308   PRVLQVQAQVQSQTQPRIPSTDTQVQ-----PKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 362
             P+  + +A+V++   P +    T +      P + K+A+ +   E     +  ++   ++
Sbjct: 11021 PKP-KPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKK 11079

Query: 363   EAEPQKQVQPQVHTQAQPSVQPQEHP 388
                P +  + ++   +     P E P
Sbjct: 11080 TPSPIEAERRKLRPGSGGEKPPDEAP 11105



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 55/290 (18%), Positives = 101/290 (34%), Gaps = 30/290 (10%)

Query: 181  PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240
            P K        T   K +    K + P  +    EP+   PE++ L        K KR  
Sbjct: 9633 PAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLK------LKPKREE 9686

Query: 241  APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 300
             P  +  E  +   K  + S E  ++EP        QP   +T+ ++ +    L E  EA
Sbjct: 9687 EPPAKVTEFRKRVVKEEKVSIEAPKREP--------QPIKEVTIMEEKERAYTLEE--EA 9736

Query: 301  QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL 360
              + R +      +   +   +        Q +   +++ +     E  + + ++  P  
Sbjct: 9737 VSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVK 9796

Query: 361  QQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ---PPEQTHEQP----HTQPQVSLL 413
                EP          +      P+E  P  +  +   PP +  E+P      + ++S+ 
Sbjct: 9797 PVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISIT 9856

Query: 414  APEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEP---VGTQVSMEEIQNE 460
              E+  V      + M P  V A    E+ +P P   V   V + E+  E
Sbjct: 9857 KREKEQVTEPAAKVPMKPKRVVA----EEKVPVPRKEVAPPVRVPEVPKE 9902


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 77/299 (25%), Positives = 109/299 (36%), Gaps = 45/299 (15%)

Query: 189 SSTTPNRKTMPVEDKSDPPEGSEEAAEPRM------DTPEDQDLPPCPEDIAKEKRTPAP 242
           +S    +KT P    +DP   +E +  PR         P    LP  P    +++ T  P
Sbjct: 339 ASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQP 398

Query: 243 EPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL--EA 300
            P+   +S  P   L S  +P  + PP Q   + Q +     P   QTP    + L  +A
Sbjct: 399 PPQAAGSSNQPGL-LASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQA 457

Query: 301 QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK----LQKQAQTQT------------ 344
           Q  P+ Q ++   Q Q Q Q  P       Q QP      Q+QAQTQ             
Sbjct: 458 QATPQHQQQLFLKQQQQQQQPPP------AQQQPAGTFYQQQQAQTQQFQAVHPATQQPA 511

Query: 345 ----------SPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQP--QEHPPAQV 392
                       +  ++Q    Q Q QQ+ + Q+Q+   +H Q   + Q   Q+ P    
Sbjct: 512 IAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAA 571

Query: 393 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQ 451
             QP  Q    P  QP  +     Q PV         PP AV+       T P    TQ
Sbjct: 572 GQQPQPQPAAAP--QPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKTQ 628



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 56/207 (27%), Positives = 82/207 (39%), Gaps = 21/207 (10%)

Query: 229 CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV--KAQPQARMTVPK 286
           CP    +    PA  PEP +ASE  AK+ +     T+  P  +  +  + +P+A  T P 
Sbjct: 319 CPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQP- 377

Query: 287 QTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL---------- 336
               P +LP  ++  + PR +  V        S  QP + ++  Q +P+           
Sbjct: 378 ---NPGILP--IQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQ 432

Query: 337 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQP--QEHPPAQVSV 394
            KQ Q   +P+     Q Q  P  Q +A PQ Q Q  +  Q Q    P  Q+ P      
Sbjct: 433 AKQPQAPPTPQQTPSTQAQGLP-AQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQ 491

Query: 395 QPPEQTHEQPHTQPQVSLLAPEQTPVV 421
           Q   QT +     P     A  Q PVV
Sbjct: 492 QQQAQTQQFQAVHPATQQPAIAQFPVV 518



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 31/67 (46%), Positives = 34/67 (50%), Gaps = 6/67 (8%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQA------PLPMAVSR 57
           QQ  Q   QQQQQ QQ QQQQ     L QQQL+  Q  LQQ P  A      P P A  +
Sbjct: 525 QQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQ 584

Query: 58  GLPPQQP 64
             P Q+P
Sbjct: 585 PAPAQEP 591



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 68/236 (28%), Positives = 87/236 (36%), Gaps = 36/236 (15%)

Query: 5   QQQQQLQQQQQQLQQLQQQQ------LQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58
           QQQ  L+QQQQQ Q    QQ       QQQQ Q QQ   +    QQ P  A  P+    G
Sbjct: 464 QQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQ-PAIAQFPVVSQGG 522

Query: 59  LPP-------QQPQQPLLNLQGTNSASLLNGS--MLQRALLL--------QQLQGLDQFA 101
                     QQ QQ     Q    A+ L+    M Q+A L         QQ Q     A
Sbjct: 523 SQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAA 582

Query: 102 MPPATYDTAGLTMPTATLGNLRGY-GMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLL 160
             PA      +  P      ++     A  G    SLTPP  ++P  Q+   +     + 
Sbjct: 583 PQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPP--SSPKTQRAGHRRILSDVT 640

Query: 161 GPPPVGVPMNPSQFNL------SGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGS 210
                GVP + S   L      +  N  K A T+ S +P      V    +P EGS
Sbjct: 641 HSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNV---YNPSEGS 693



 Score = 30.0 bits (66), Expect = 9.3
 Identities = 24/69 (34%), Positives = 27/69 (39%), Gaps = 5/69 (7%)

Query: 3   SQQQQQQLQQQQQQLQQLQQQQLQQQ-----QLQQQQLLQLQQLLQQSPPQAPLPMAVSR 57
           +Q +Q Q     QQ    Q Q L  Q     Q QQQ  L+ QQ  QQ PP    P     
Sbjct: 431 TQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFY 490

Query: 58  GLPPQQPQQ 66
                Q QQ
Sbjct: 491 QQQQAQTQQ 499


>gi|197276594 RNA binding motif protein 20 [Homo sapiens]
          Length = 1227

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)

Query: 634  KTPRKFVEHVKSQGH-KDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 692
            + P  FV+  K++G  +D A E   LE++ +   E     +    C E    E     + 
Sbjct: 1057 RQPSPFVDDCKTRGTPEDGACEGSPLEEKASPPIETD---LQNQACQEVLTPENSRYVEM 1113

Query: 693  EEIEVEEELCKQVRSRD-ISREEWKGSETYSP-NTAYGVDFLVPVMGYICRICHKFYHSN 750
            + +EV      +V  +  +S   W+  + +S  +   GV+F+VP  G+ C++C  FY S 
Sbjct: 1114 KSLEVRSPEYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSE 1173

Query: 751  SGAQLSHCKSLGHFENLQKY 770
              A++SHC+S  H+ NLQKY
Sbjct: 1174 ETAKMSHCRSAVHYRNLQKY 1193


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 67/306 (21%), Positives = 117/306 (38%), Gaps = 45/306 (14%)

Query: 203  KSDPPEGSE--EAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSS 260
            +SD  EG E  EA        E  + P    D  + +    PE E  EA E   +    S
Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPES 1887

Query: 261  EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 320
            E+    E   ++Q +++        K+ Q      EALE +                  +
Sbjct: 1888 EDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETE-----------------GE 1930

Query: 321  TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQ--- 377
             +P     + Q   +  ++A+ QT PE  V++ ++ + + Q E+E  + ++ +V TQ   
Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAE 1990

Query: 378  --AQPSVQPQEHPPAQ----------------VSVQPPEQTHEQPHTQPQVSLLAPEQTP 419
              AQP  +  E P A+                V  QP  +  E    + +      +  P
Sbjct: 1991 GEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQP 2050

Query: 420  VVVHVCGLEMPPDAVEAGGGMEKTLPE--PVGTQVSMEEIQNES---ACGLDVGECENRA 474
                V   E   +A EA G +++   E  P    V  +E + E+   + G++  E E  A
Sbjct: 2051 ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEA 2110

Query: 475  REMPGV 480
            ++  G+
Sbjct: 2111 QKAEGI 2116



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 59/245 (24%), Positives = 98/245 (40%), Gaps = 18/245 (7%)

Query: 181  PQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 240
            P+     +   +   +   VE ++   EG  +     ++ PE ++     E   +E    
Sbjct: 2018 PESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGE 2077

Query: 241  A-PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALE 299
            A PE E  +A E   +    SE     E  G+ Q KA+         + Q      EA E
Sbjct: 2078 AHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQ-KAEGIEAPETEGEAQPESEGIEAPE 2136

Query: 300  AQVLPRFQPRVLQVQAQ-VQSQTQPRIPSTDTQ-----VQPKLQ----KQAQTQTSPEHL 349
            A+     QP    V+AQ  + + QP     + Q      QP+L+     +A+ +  PE  
Sbjct: 2137 AE--GEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESE 2194

Query: 350  VLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQ--THEQPHTQ 407
             ++  + + + Q E E  +   P+   +AQP  +  E P A+   QP  +  T  +    
Sbjct: 2195 GIEAPEAEGEAQPELEGVEA--PEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGS 2252

Query: 408  PQVSL 412
            PQVSL
Sbjct: 2253 PQVSL 2257



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 59/244 (24%), Positives = 99/244 (40%), Gaps = 24/244 (9%)

Query: 199  PVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCPEDI-AKEKRTPA-PEPEPCEASELP-- 253
            P  D  + PE  EEA E   +  E + +  P  ED+ A+E    A PE E  EA E    
Sbjct: 2050 PESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGE 2109

Query: 254  ---AKRLRSSEEPTEKEPPGQ------LQVKAQPQARMTVPKQTQTPDLLPEA--LEAQV 302
               A+ + + E   E +P  +       + +AQP++   V  Q    +  PE+  +EAQ 
Sbjct: 2110 AQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE-GVEAQDAEGEAQPESEGIEAQE 2168

Query: 303  LPR-FQPRVLQVQA-QVQSQTQPR-----IPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355
                 QP +  V+A + + + QP       P  + + QP+L+     +   E     +  
Sbjct: 2169 AEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGV 2228

Query: 356  VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 415
              P+ + EA+P+ + + Q   +  P V   +    + S        ++P   P      P
Sbjct: 2229 ETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTP 2288

Query: 416  EQTP 419
             Q P
Sbjct: 2289 HQRP 2292



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 87/437 (19%), Positives = 157/437 (35%), Gaps = 64/437 (14%)

Query: 182  QKQARTSSSTTPNRK--TMPVEDKSDPPEGSEEAAEPRMDTPE--DQDLPPCPEDIAKEK 237
            + Q  +    TP  +    P  + ++ PE  +EA +P  ++ E  + +    PE    E 
Sbjct: 1882 EAQPESEDVETPEAEWEVQPESEGAEAPEAEKEA-QPETESVEALETEGEDEPESEGAEA 1940

Query: 238  RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEA 297
            +      +  E    P   +  S+E  E+  P    V+A     + V  Q    +  PE+
Sbjct: 1941 QEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEA---LEVEVETQEAEGEAQPES 1997

Query: 298  LEAQVLPRFQPRVLQVQAQVQSQT-----QPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 352
             + +  P  +  + + + + Q ++     QP+    + Q      ++ +    PE   ++
Sbjct: 1998 EDVEA-PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVE 2056

Query: 353  QKQVQPQLQQEAEPQKQVQPQVHT------------QAQPSVQPQEHPPAQVSVQPPEQT 400
              + + + Q+     ++ + + H             +AQP  +  E P A+   Q  E  
Sbjct: 2057 APEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGI 2116

Query: 401  HEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA--VEAGGGMEKTLPEPVG--TQVSMEE 456
             E P T+ +     PE   +       E  P++  VEA     +  PE  G   Q + EE
Sbjct: 2117 -EAPETEGEAQ---PESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEE 2172

Query: 457  IQNESACGLDVGECENRAR-EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSV 515
             Q E   G++  E E  A+ E  G+              ++  A   +     P   +  
Sbjct: 2173 AQPELE-GVEAPEAEGEAQPESEGIEA----------PEAEGEAQPELEGVEAPEAEEEA 2221

Query: 516  SSTPAATSTPSKQALQFFCYICKASCSSQQEFQ-DHMSEPQHQQRLGEIQHMSQACLLSL 574
               P    TP  +         +A   S+ E Q +    PQ     G+ +  S+    S 
Sbjct: 2222 QPEPEGVETPEAEG--------EAQPESEGETQGEKKGSPQVSLGDGQSEEASE----SS 2269

Query: 575  LPVPRDVLETEDEEPPP 591
             PVP D        PPP
Sbjct: 2270 SPVPED-----RPTPPP 2281



 Score = 30.0 bits (66), Expect = 9.3
 Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 14/89 (15%)

Query: 640  VEHVKSQGHKD------KAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEE 693
            VE ++++G  +      +A+E +   +E  GQ +     +++    E +EE + + ED E
Sbjct: 1922 VEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ---EAEEEAQPESEDVE 1978

Query: 694  EIEVEEELCK-----QVRSRDISREEWKG 717
             +EVE E  +     Q  S D+   E +G
Sbjct: 1979 ALEVEVETQEAEGEAQPESEDVEAPEAEG 2007


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 70/251 (27%), Positives = 111/251 (44%), Gaps = 26/251 (10%)

Query: 178 GRNPQKQARTSSSTTPNRKTMPVEDKSDP-------PEGSEEAAEPRMDTPEDQDLPPCP 230
           G  P   +  S  +    +  P E  S P       P G+ E AE     P  ++L    
Sbjct: 36  GPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETR--PGQREL---- 89

Query: 231 EDIAKEKRTPAPEPEPC-EASELPAKRLRSSEEPTEKEPPGQLQV-KAQPQARMTVPKQT 288
             + + ++ P P+ +P  E  + P   L   ++P +    GQ Q+ + Q +   +V  Q 
Sbjct: 90  -QLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQD---GQQQLSQLQQEKHQSVHHQE 145

Query: 289 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS-PE 347
             P+L     + Q+    QP+ +Q Q ++Q Q Q ++ +   Q Q  LQ+Q Q Q    E
Sbjct: 146 LKPELQLMHQQQQL----QPQQVQEQQRLQQQ-QEQLQTQQAQEQQVLQQQEQLQQQVQE 200

Query: 348 HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEH-PPAQVSVQPPEQTHEQPHT 406
             +LQQ+Q Q Q QQ  + Q+Q+Q Q   Q Q  +Q Q+     Q   Q  +Q  +Q   
Sbjct: 201 QQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQA 260

Query: 407 QPQVSLLAPEQ 417
           Q Q  LL  +Q
Sbjct: 261 QLQQQLLEQQQ 271



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 50/107 (46%), Positives = 59/107 (55%), Gaps = 19/107 (17%)

Query: 5   QQQQQLQQQ-------QQQLQQLQQQQL--QQQQLQQQQLLQLQQLLQQSPPQAPLPMAV 55
           QQQ+QLQQQ       QQQ +QLQQQQL  QQ+QLQQQQ  Q Q+ LQQ   Q  L +  
Sbjct: 189 QQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQ---QQQLLLLQ 245

Query: 56  SRGLPPQQPQQPLLNLQGTNSASLL---NGSMLQRALLLQQLQGLDQ 99
            +G    Q QQ LL  Q       L     + LQ+ LLLQQ + L Q
Sbjct: 246 QQG----QLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 40/96 (41%), Positives = 47/96 (48%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           M  QQQ Q  Q Q+QQ  Q QQ+QLQ QQ Q+QQ+LQ Q+ LQQ   +  L       L 
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG 96
            QQ  Q    LQ             Q+ LLL Q QG
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQG 248



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 5/185 (2%)

Query: 230 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL--QVKAQPQARMTVPKQ 287
           P+ + +++R    + +         + L+  E+  ++    QL  Q + Q Q +  + +Q
Sbjct: 161 PQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ 220

Query: 288 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 347
            Q      +  + Q+  + Q  +LQ Q Q+Q Q    +     Q+Q +L +Q Q Q   +
Sbjct: 221 EQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL---LQQQQAQLQQQLLEQQQAQLQQQ 277

Query: 348 HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 407
            L+ QQ+Q+Q Q QQ+   Q+Q Q Q      P ++P+E    ++ + P +   EQ   Q
Sbjct: 278 LLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQ 337

Query: 408 PQVSL 412
            +  L
Sbjct: 338 QRQEL 342



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 35/66 (53%), Positives = 40/66 (60%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
           QQQQ+QLQQQQQ L   QQ QLQQQ LQQQQ    QQLL+Q   Q    + + +    QQ
Sbjct: 229 QQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288

Query: 64  PQQPLL 69
            QQ  L
Sbjct: 289 QQQQQL 294



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 67/261 (25%), Positives = 112/261 (42%), Gaps = 15/261 (5%)

Query: 171 PSQFNLSGRNPQKQARTSSS-----TTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQ- 224
           P + N S + P   A   +S     T P ++ + ++     PE  ++    ++  P+   
Sbjct: 57  PQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHL 116

Query: 225 DLPPCPEDIAKEKRTPAPEPEPCEASELPAK-RLRSSEEPTEKEPPG-QLQVKAQPQARM 282
           +L   P+   +++ +   + +         K  L+   +  + +P   Q Q + Q Q   
Sbjct: 117 ELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQ 176

Query: 283 TVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQT 342
              +Q Q   +L +  + Q   + Q  + Q Q Q+Q Q Q        Q Q   Q+Q Q 
Sbjct: 177 LQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ-QLLQQQEQLQQQQFQQQQEQL 235

Query: 343 QTSPEHLVLQQK-QVQPQL--QQEAEPQKQV--QPQVHTQAQPSVQPQEHPPAQVSVQPP 397
           Q   + L+LQQ+ Q+Q QL  QQ+A+ Q+Q+  Q Q   Q Q  +Q QE    Q   Q  
Sbjct: 236 QQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLL 295

Query: 398 EQTHEQ-PHTQPQVSLLAPEQ 417
           +Q  EQ    Q Q   L PE+
Sbjct: 296 QQQQEQLQQQQLQPPPLEPEE 316



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 47/102 (46%), Positives = 57/102 (55%), Gaps = 9/102 (8%)

Query: 5   QQQQQLQQQQQQLQ--QLQQQQL--QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSR--G 58
           Q+QQ+LQQQQ+QLQ  Q Q+QQ+  QQ+QLQQQ  +Q QQLLQQ   Q      + +   
Sbjct: 165 QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQ--VQEQQLLQQQQEQLQQQQLLQQQEQ 222

Query: 59  LPPQQPQQPLLNLQGTNSASLL-NGSMLQRALLLQQLQGLDQ 99
           L  QQ QQ    LQ      LL     LQ+ LL QQ   L Q
Sbjct: 223 LQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQ 264



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 39/69 (56%), Positives = 42/69 (60%), Gaps = 5/69 (7%)

Query: 5   QQQQQLQQQ--QQQLQQLQQQQLQQQ--QLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           QQQ QLQQQ  QQQ  QLQQQ L+QQ  QLQQQ LLQ Q+ LQQ   Q  L     + L 
Sbjct: 245 QQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQ-LQ 303

Query: 61  PQQPQQPLL 69
            QQ Q P L
Sbjct: 304 QQQLQPPPL 312



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 38/79 (48%), Positives = 45/79 (56%), Gaps = 10/79 (12%)

Query: 3   SQQQQQQLQQQQQQLQQ--LQQQQLQQQQLQQQQLLQLQQ-LLQQSPPQAPLPMAVSRGL 59
           +Q QQQ L+QQQ QLQQ  L QQQ Q QQ QQQQLLQ QQ  LQQ   Q P        L
Sbjct: 260 AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPP-------PL 312

Query: 60  PPQQPQQPLLNLQGTNSAS 78
            P++ ++  L L   +  S
Sbjct: 313 EPEEEEEVELELMPVDLGS 331



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 47/255 (18%), Positives = 104/255 (40%), Gaps = 11/255 (4%)

Query: 169 MNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPP 228
           + P Q     R  Q+Q +  +     ++ +  +++       ++  + + +  + Q L  
Sbjct: 159 LQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQ 218

Query: 229 CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA--QPQARMTVPK 286
             E + +++     E    +   L  ++    ++   ++   QLQ +   Q QA++    
Sbjct: 219 QQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQL 278

Query: 287 QTQTPDLLPEALEAQVLPRFQPRVLQVQAQV-------QSQTQPRIPSTDTQVQPKLQKQ 339
             Q  + L +  + Q+L + Q ++ Q Q Q        + + +  +   D   + +L++Q
Sbjct: 279 LLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQ 338

Query: 340 AQTQTSPEHLVLQQ--KQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPP 397
            Q     + L  QQ  +Q+Q +LQ+E +  +Q   Q   Q +      E  P ++  Q  
Sbjct: 339 RQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQ 398

Query: 398 EQTHEQPHTQPQVSL 412
           E   E    QP++ L
Sbjct: 399 EVQLELTPVQPELQL 413



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 91/420 (21%), Positives = 155/420 (36%), Gaps = 48/420 (11%)

Query: 12  QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNL 71
           Q++ QLQQL+QQ   QQQ Q +QL            Q P P    +  P Q  QQ L  L
Sbjct: 86  QRELQLQQLEQQPEPQQQPQHEQL------------QQPQPHLELQQQPQQDGQQQLSQL 133

Query: 72  QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPG 131
           Q     S+ +  +     L+ Q Q L     P    +   L      L   +        
Sbjct: 134 QQEKHQSVHHQELKPELQLMHQQQQL----QPQQVQEQQRLQQQQEQLQTQQ--AQEQQV 187

Query: 132 LAAPSLTPPQLATPN-LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSS 190
           L        Q+     LQQ   Q  +Q LL        +   QF       Q+Q +    
Sbjct: 188 LQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE---QLQQQQFQQQQEQLQQQQQLLLL 244

Query: 191 TTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEAS 250
               +    +  +    +  ++  E +    + Q L    E + ++++    +    +  
Sbjct: 245 QQQGQLQQQLLQQQQ-AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQ---QQE 300

Query: 251 ELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRV 310
           +L  ++L+    P E E   +++++  P   + +  + +      E    Q L R Q   
Sbjct: 301 QLQQQQLQ--PPPLEPEEEEEVELELMP---VDLGSEQELEQQRQELERQQELER-QQEQ 354

Query: 311 LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQV 370
            Q+Q ++Q + Q      + Q Q   Q++ Q + +P  L  QQ++VQ +L         V
Sbjct: 355 RQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLEL-------TPV 407

Query: 371 QPQVHTQAQPSV----QPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCG 426
           QP++  +  P+           PA V V PP     Q     ++ +L     P VV + G
Sbjct: 408 QPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQ-----ELMVLPAVAAPAVVAIPG 462



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 42/111 (37%), Positives = 49/111 (44%), Gaps = 20/111 (18%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQL-------------QQQQLQQQQLLQLQQLLQQSPPQAP 50
           QQ QQ  QQQ  QLQQ + Q +             QQQQLQ QQ+ Q QQ LQQ   Q  
Sbjct: 120 QQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQV-QEQQRLQQQQEQLQ 178

Query: 51  LPMAVSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGLDQ 99
              A  + +  QQ Q      Q      LL      LQ+  LLQQ + L Q
Sbjct: 179 TQQAQEQQVLQQQEQLQ----QQVQEQQLLQQQQEQLQQQQLLQQQEQLQQ 225



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 31/74 (41%), Positives = 45/74 (60%), Gaps = 6/74 (8%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQ---QQQLQQ--QQLLQLQQLLQQSPPQAPLPMAVSRG 58
           +QQ+Q+L++QQ+  +Q +Q+QLQ   Q++LQQ  QQL Q QQ L+Q   Q  L   V  G
Sbjct: 336 EQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLEL-TPVELG 394

Query: 59  LPPQQPQQPLLNLQ 72
              Q+ Q  L  +Q
Sbjct: 395 AQQQEVQLELTPVQ 408



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 47/175 (26%)

Query: 4   QQQQQQLQQQQQQLQQLQQQ----------------------------------QLQQQQ 29
           QQQQQ LQQQQ+QLQQ Q Q                                  + QQ+ 
Sbjct: 289 QQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQEL 348

Query: 30  LQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRAL 89
            +QQ+  QLQ  LQ+   Q      + + L  QQ Q     +Q   +   L     +  L
Sbjct: 349 ERQQEQRQLQLKLQEELQQ------LEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQL 402

Query: 90  LLQQLQGLDQFAMPPATYDTAGLT--MPTATLGNLRGYG-----MASPGLAAPSL 137
            L  +Q   Q  + PA           P A +    GY      M  P +AAP++
Sbjct: 403 ELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQELMVLPAVAAPAV 457


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 45/98 (45%), Positives = 50/98 (51%), Gaps = 6/98 (6%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQ-----QQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58
           QQQQQQ QQQQQQ QQ QQQQ Q     QQQ QQQ  +  QQ  QQ   Q        + 
Sbjct: 599 QQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQ 658

Query: 59  LPPQQPQQPLLNLQGTNSASLLNGSM-LQRALLLQQLQ 95
              QQ Q      Q   S  LL   + LQ+ LLLQQ+Q
Sbjct: 659 QQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 106/498 (21%), Positives = 178/498 (35%), Gaps = 102/498 (20%)

Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 188
           SPGL       PQL  P+    F  A        P   VP + +Q       PQ  +  S
Sbjct: 369 SPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQ-------PQTGSGAS 421

Query: 189 SSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCE 248
            +    ++    +         ++ A  +    + Q     P + +    +  P P P  
Sbjct: 422 RALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQ-----PTNWSALPSSAGPSPGPFG 476

Query: 249 ASELPAKRL-------RSSEEPTEKEPPGQLQV------KAQPQAR---MTVPKQTQTPD 292
             ++P+          +SS  P      GQ +V      KA P A+   + V  Q Q P 
Sbjct: 477 QEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQ-QKPQ 535

Query: 293 LLPEALEAQVLPRFQPRV---------------LQVQAQVQSQTQPRIPSTDTQVQPKLQ 337
            L  +      P  +PR                 Q+ + + SQ +P +     Q Q + Q
Sbjct: 536 DLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQ 595

Query: 338 KQAQTQTSPEHLVLQQKQVQPQLQQE----AEPQKQVQPQVHTQAQPSVQPQEHPPAQVS 393
           +Q Q Q   +    QQ+Q Q Q QQ+    A+ Q+Q Q  +  Q Q   Q Q+    Q  
Sbjct: 596 QQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQ 655

Query: 394 VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVS 453
            Q  +Q  +QP +QP  SL  P Q P++                       P P+  ++ 
Sbjct: 656 QQQQQQQQQQPSSQPAQSL--PSQ-PLL---------------------RSPLPLQQKLL 691

Query: 454 MEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSD 513
           ++++QN+   G+     + + ++   V G                        P P P+ 
Sbjct: 692 LQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTG--------------------PSPSPNP 731

Query: 514 SVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLS 573
             +    +    S+Q+L     + +     +Q  Q  + E Q QQ L + Q ++ A  ++
Sbjct: 732 CSNPNTGSGYMNSQQSL-----LNQQLMGKKQTLQRQIME-QKQQLLLQQQMLADAEKIA 785

Query: 574 LLPVPRDVLETEDEEPPP 591
               P+D +      PPP
Sbjct: 786 ----PQDQINRHLSRPPP 799



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 32/66 (48%), Positives = 38/66 (57%), Gaps = 1/66 (1%)

Query: 6   QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65
           QQQQ QQQQQQ QQ QQQQ QQQQ QQ      Q L  Q   ++PLP+   + L  Q   
Sbjct: 639 QQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ-QKLLLQQMQN 697

Query: 66  QPLLNL 71
           QP+  +
Sbjct: 698 QPIAGM 703



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 79/331 (23%), Positives = 110/331 (33%), Gaps = 18/331 (5%)

Query: 3   SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
           SQ +   L   QQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ           S     Q
Sbjct: 577 SQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQS-------SISAQQQ 629

Query: 63  QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAG-LTMPTATLGN 121
           Q QQ  ++ Q             Q+    QQ Q     + P  +  +   L  P      
Sbjct: 630 QQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQK 689

Query: 122 LRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP 181
           L    M +  +A       Q    +      Q T  S   P P   P   S +  S ++ 
Sbjct: 690 LLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPS-PSPNPCSNPNTGSGYMNSQQSL 748

Query: 182 QKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQ---DLPPCPEDIAKEKR 238
             Q       T  R+ M  E K       +  A+     P+DQ    L   P D  K++R
Sbjct: 749 LNQQLMGKKQTLQRQIM--EQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDY-KDQR 805

Query: 239 TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL 298
                 +P       +  +  +       P     +     + ++    T+ P L     
Sbjct: 806 RNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQ 865

Query: 299 EAQV---LPRFQPRVLQVQAQVQSQTQPRIP 326
              +   LP  QP    V + +   TQ R P
Sbjct: 866 NMGMYGNLPCNQPNTYSVTSGMNQLTQQRNP 896



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 29/97 (29%), Positives = 35/97 (36%)

Query: 3   SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
           +QQ    L  Q +       QQ QQQQ QQQQ  Q QQ  QQ   Q          +  Q
Sbjct: 568 NQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQ 627

Query: 63  QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQ 99
           Q QQ   ++              Q+    QQ Q   Q
Sbjct: 628 QQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQ 664



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 75/411 (18%), Positives = 149/411 (36%), Gaps = 56/411 (13%)

Query: 6   QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65
           Q+    QQ +Q+   +QQ  + QQ QQQ        L  S   +P P    +   P   Q
Sbjct: 428 QEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQ 487

Query: 66  Q-------PLLNLQGTNSASLLNGSMLQRALLLQQLQGLD-QFAMPPATYDTAGLTMPTA 117
           Q       P+  + G +  S +  + + +A    Q   LD      P     + +  P  
Sbjct: 488 QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNP-- 545

Query: 118 TLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLS 177
                            P++ P Q  T  L  F      Q +  P  +     PS  + +
Sbjct: 546 ----------------HPAMEPRQGNTKPLFHFNSDQANQQM--PSVLPSQNKPSLLHYT 587

Query: 178 GRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 237
            +  Q+Q +        ++    + +    +  + +   +    +          I+ ++
Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQ-------SSISAQQ 640

Query: 238 RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEA 297
           +    + +  +  +   ++ +  ++P+ +  P Q  + +QP  R  +P Q +   LL + 
Sbjct: 641 QQQQQQQQQQQQQQQQQQQQQQQQQPSSQ--PAQ-SLPSQPLLRSPLPLQQK---LLLQQ 694

Query: 298 LEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ 357
           ++ Q +     +V    +Q Q Q Q  +   +T   P     +   T   ++  QQ  + 
Sbjct: 695 MQNQPIAGMGYQV----SQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLN 750

Query: 358 PQ-------LQQEAEPQKQ---VQPQVHTQAQPSVQPQEHPPAQVSVQPPE 398
            Q       LQ++   QKQ   +Q Q+   A+  + PQ+     +S  PP+
Sbjct: 751 QQLMGKKQTLQRQIMEQKQQLLLQQQMLADAE-KIAPQDQINRHLSRPPPD 800



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 75/332 (22%), Positives = 126/332 (37%), Gaps = 41/332 (12%)

Query: 2    FSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLL---QQSPPQAPLPMAVSRG 58
            +   QQ  L QQ    +Q  Q+Q+ +   Q+QQLL  QQ+L   ++  PQ  +   +SR 
Sbjct: 741  YMNSQQSLLNQQLMGKKQTLQRQIME---QKQQLLLQQQMLADAEKIAPQDQINRHLSRP 797

Query: 59   LPPQQPQ-------QPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAG 111
             P  + Q       QP     G +S   LN +      +          ++   ++ T  
Sbjct: 798  PPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRM 857

Query: 112  LTMPTATLGNLRGYG---MASPGLAAPSLTPPQLATP-NLQQFFPQATRQSLLGPPPVGV 167
             ++ TA + N+  YG      P   + +    QL    N +Q         +  PP +G 
Sbjct: 858  PSLSTA-VQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGP 916

Query: 168  PMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP 227
              N +       +     +   + T +  +MP +  S+    S   A P   + E     
Sbjct: 917  SNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTA-PNWASQEGTSK- 974

Query: 228  PCPEDIAKEKRTPAPE--PEPCEASELPAKRLR---SSEEPTEK--EPPGQL----QVKA 276
                   +E  T A    P    A+  P + L+    S++ +++   PP QL    Q++ 
Sbjct: 975  ------QQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRP 1028

Query: 277  QPQARMTVPKQTQTP----DLLPEALEAQVLP 304
              Q   T+  QT  P    +L P  L  Q+LP
Sbjct: 1029 MNQMSQTLNGQTMGPLRGLNLRPNQLSTQILP 1060


>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
          Length = 1200

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 113/462 (24%), Positives = 170/462 (36%), Gaps = 99/462 (21%)

Query: 5   QQQQQLQQQQQQLQQLQQQQL---QQQQLQQQQLLQLQQLL---QQSPPQAPLPMAVSRG 58
           Q  Q  Q   Q +QQ+QQ Q    QQQQ   QQ + +Q++    QQ  P  P P      
Sbjct: 249 QPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQP------ 302

Query: 59  LPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAM---PPATY-------D 108
            PPQQ Q   L LQ     S+      Q   ++Q LQ   Q  M   PP+ +        
Sbjct: 303 -PPQQQQPQQLQLQ-QRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP 360

Query: 109 TAGLTMPTATLGNLRGYGMASPGLAAPSLTP----------PQLATPNLQQFFPQATRQS 158
               T+    LG++  Y    P    P   P           Q     L+ +      Q+
Sbjct: 361 EQAHTVQLIPLGSMSQYYYQEP--QQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQA 418

Query: 159 L------LGPPPVGVP-------------------MNPSQFNLSGRNPQKQARTSSSTTP 193
           +      LGPP  G+                    ++PS  +L+   PQ Q  + S+  P
Sbjct: 419 MLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWP 478

Query: 194 NRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELP 253
               M + D    P   E + +P+    E  D        AK K T +   +  E   LP
Sbjct: 479 Q---MHLPDGRAQPGSPESSGQPKGAFGEQFD--------AKNKLTCSICLK--EFKNLP 525

Query: 254 A--KRLRS----SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP---EALEAQVLP 304
           A    +RS       P  K+  G+  +  QPQ  +  P     P  LP   E+L   V+P
Sbjct: 526 ALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMP 585

Query: 305 RFQP-RVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ-QKQVQPQLQQ 362
              P ++L  +   Q  T   + +   + +P     A + +  E  VL+  ++ QP + +
Sbjct: 586 VSVPVKLLPPKPSSQGFTNSTVAAPSARDKP-----ASSMSDDEMPVLEIPRKHQPSVPK 640

Query: 363 EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQP 404
             EP K VQ +         +   H P  + + PP   +  P
Sbjct: 641 AEEPLKTVQEK---------KKFRHRPEPLFIPPPPSYNPNP 673



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 55/221 (24%), Positives = 96/221 (43%), Gaps = 11/221 (4%)

Query: 194 NRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELP 253
           N     +  +S   +G+ ++A  ++ + +  + PP P   ++ ++ P  +P P     L 
Sbjct: 160 NNMAQVLHTQSAVMDGAPDSALRQLLSQKPME-PPAPAIPSRYQQVPQ-QPHPGFTGGLS 217

Query: 254 AKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP--KQTQTPDLLPEALEAQVLPRFQPRVL 311
              L+  + PT+       Q   QP A++ V   +  Q P +L + ++     ++ P   
Sbjct: 218 KPALQVGQHPTQGHLYYDYQ---QPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQ 274

Query: 312 QVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQ 371
           Q QA  Q  +   I +   Q++P   +    Q  P+ L LQQ+Q   Q+ Q  +PQ  +Q
Sbjct: 275 QQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQ 334

Query: 372 PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL 412
              H Q Q   Q    PP+     P + T EQ HT   + L
Sbjct: 335 ---HLQEQQQQQMHLQPPS-YHRDPHQYTPEQAHTVQLIPL 371


>gi|4507379 TATA box binding protein [Homo sapiens]
          Length = 339

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 34/62 (54%), Positives = 38/62 (61%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
           QQQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ +  +  Q       ++G   Q 
Sbjct: 59  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQA 118

Query: 64  PQ 65
           PQ
Sbjct: 119 PQ 120



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 33/60 (55%), Positives = 36/60 (60%)

Query: 6   QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65
           ++QQ QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ   QA    AV +    Q  Q
Sbjct: 53  EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 30/60 (50%), Positives = 35/60 (58%)

Query: 7   QQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQ 66
           ++Q +QQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ   Q  +  A  +    QQ  Q
Sbjct: 53  EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 31/66 (46%), Positives = 36/66 (54%), Gaps = 2/66 (3%)

Query: 10  LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLL 69
           L++QQ+Q QQ QQQQ QQQQ QQQQ  Q QQ  QQ   Q     AV+     Q   Q   
Sbjct: 52  LEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQA- 110

Query: 70  NLQGTN 75
             QGT+
Sbjct: 111 -TQGTS 115



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 27/63 (42%), Positives = 31/63 (49%)

Query: 11  QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLN 70
           +QQ+QQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ   Q       +  +     QQ    
Sbjct: 54  EQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQG 113

Query: 71  LQG 73
             G
Sbjct: 114 TSG 116



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 27/66 (40%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLL-QQSPPQAPLPMAVSRGLPPQ 62
           QQQQQQ QQQQQ +     QQ   QQ  Q    Q  QL   Q+   APLP        P 
Sbjct: 84  QQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPM 143

Query: 63  QPQQPL 68
            P  P+
Sbjct: 144 TPMTPI 149



 Score = 38.5 bits (88), Expect = 0.026
 Identities = 22/44 (50%), Positives = 25/44 (56%)

Query: 5  QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQ 48
          Q    L   ++Q +Q QQQQ QQQQ QQQQ  Q QQ  QQ   Q
Sbjct: 44 QNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 87



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 24/84 (28%), Positives = 38/84 (45%)

Query: 337 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP 396
           Q++ Q Q   +    QQ+Q Q Q QQ+ + Q+Q Q Q   QA  +   Q+    Q +   
Sbjct: 55  QQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGT 114

Query: 397 PEQTHEQPHTQPQVSLLAPEQTPV 420
             Q  +  H+Q   +   P  TP+
Sbjct: 115 SGQAPQLFHSQTLTTAPLPGTTPL 138



 Score = 37.0 bits (84), Expect = 0.076
 Identities = 28/112 (25%), Positives = 42/112 (37%)

Query: 295 PEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQK 354
           P+      +P F P +           Q     +  + Q + Q+Q Q Q   +    QQ+
Sbjct: 17  PQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQ 76

Query: 355 QVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHT 406
           Q Q Q QQ+ + Q+Q Q Q    A       +      S Q P+  H Q  T
Sbjct: 77  QQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLT 128



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 31/124 (25%), Positives = 43/124 (34%)

Query: 308 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ 367
           P   Q  A  Q    P IP     +        Q   +   L + ++Q + Q QQ+ + Q
Sbjct: 8   PPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQ 67

Query: 368 KQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL 427
           +Q Q Q   Q Q   Q Q+    Q   Q       Q  T  Q +     Q P + H   L
Sbjct: 68  QQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTL 127

Query: 428 EMPP 431
              P
Sbjct: 128 TTAP 131



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 33/117 (28%), Positives = 44/117 (37%), Gaps = 7/117 (5%)

Query: 269 PGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPST 328
           P   Q  A PQ  MT      +P ++P        P      L +  + Q Q Q +    
Sbjct: 8   PPYAQGLASPQGAMTPGIPIFSP-MMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQ--QQ 64

Query: 329 DTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQ 385
             Q Q + Q+Q Q Q   +    QQ+Q Q Q QQ+A     VQ     QA      Q
Sbjct: 65  QQQQQQQQQQQQQQQQQQQ----QQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQ 117



 Score = 30.0 bits (66), Expect = 9.3
 Identities = 42/171 (24%), Positives = 60/171 (35%), Gaps = 20/171 (11%)

Query: 12  QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNL 71
           Q  Q    L   + QQ+Q QQQQ  Q QQ  QQ   Q             QQ QQ     
Sbjct: 41  QPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQ------------QQQQQQQQQQQ 88

Query: 72  QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPG 131
           Q       +  + +Q++   Q  QG       P  + +      T T   L G     P 
Sbjct: 89  QQQQQQQAVAAAAVQQSTSQQATQGTS--GQAPQLFHS-----QTLTTAPLPGTTPLYPS 141

Query: 132 LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 182
              P +TP   ATP  +        Q+++    +G  ++     L  RN +
Sbjct: 142 PMTP-MTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAE 191


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 103/401 (25%), Positives = 131/401 (32%), Gaps = 94/401 (23%)

Query: 45  SPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPP 104
           +PP +P P+     LP   P      LQ + S ++   S L   L +  LQ L   A   
Sbjct: 450 TPPDSP-PLQAPLSLPASPP------LQTSLSPAV---SPLSSPLTIHPLQALSSLASHS 499

Query: 105 ATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164
                + L MP              P     SL PP L TP      P       L PPP
Sbjct: 500 PQAPLSSLIMP--------------PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545

Query: 165 VGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQ 224
           +                  Q  ++  TTP+ +T P      P     +A    + TP   
Sbjct: 546 L------------------QTASAPLTTPHLETPPC-----PAPCPLQAPPSPLTTPP-- 580

Query: 225 DLPPCPEDIAKEKRTPAPEPEPCEASE----LPAKRLRSSEEPTEKEPPG----QLQVKA 276
             P  P  IA    TP P+  P  AS     LP+  L     P  + PP      LQ   
Sbjct: 581 --PETPSSIA----TPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP 634

Query: 277 QPQARMTV-PKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 335
            P A   + P  T +P   P AL   +L                   P  P     VQ  
Sbjct: 635 SPPASPPLSPLATPSPQA-PNALAVHLLQA-----------------PFSPPPSPPVQAP 676

Query: 336 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVS-- 393
               A    SP        Q  P L   A P  QV P     A P + P   PP Q    
Sbjct: 677 FSPPASPPVSPS--ATPPSQAPPSL---AAPPLQVPPS--PPASPPMSPSATPPPQAPPP 729

Query: 394 -VQPPEQTHEQPHTQPQVSLLA--PEQTPVVVHVCGLEMPP 431
              PP Q    P   P +S  A  P + P ++    L++PP
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770



 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 103/412 (25%), Positives = 133/412 (32%), Gaps = 56/412 (13%)

Query: 45  SPPQAPLPMAV-SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRA---LLLQQLQGLDQF 100
           SPP  P   A  S   PP Q    L  +        L    LQ     L L  LQ     
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418

Query: 101 AMPPATYDTAGLTM-PTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL 159
             P      + LTM P  T  +L      SP  + P+ TPP   +P LQ         SL
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASL-----TSP--SRPASTPPD--SPPLQ------APLSL 463

Query: 160 LGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPP-EGSEEAAEPRM 218
              PP+   ++P+   LS        +  SS   +    P+     PP E     A P +
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523

Query: 219 DTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 278
            TP      P  E++      P+  P P + +  P         P     P    ++A P
Sbjct: 524 QTPPASLTTPPLENL------PSLAPPPLQTASAPLTTPHLETPPC----PAPCPLQAPP 573

Query: 279 QARMTVPKQTQT-----PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQ 333
               T P +T +     P   P AL +  L       L   A    Q  P +        
Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL------AL 627

Query: 334 PKLQKQAQTQTSPEHLVLQQKQVQP---------QLQQEAEPQKQVQPQVHTQAQPSVQP 384
           P LQ       SP    L     Q          Q      P   VQ      A P V P
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687

Query: 385 QEHPPAQVS---VQPPEQTHEQPHTQPQVSLLA--PEQTPVVVHVCGLEMPP 431
              PP+Q       PP Q    P   P +S  A  P Q P  +    L++PP
Sbjct: 688 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 88/368 (23%), Positives = 111/368 (30%), Gaps = 79/368 (21%)

Query: 127 MASPGLAAPSLTPPQLAT------PNLQQFFPQATRQSLLGP----PPVGVPMNPSQFNL 176
           + SP    PS  PP + T      P+LQ   P     SL  P    PP  + ++  Q   
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416

Query: 177 SGRNPQKQARTSSSTTPNRKTM-----PVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPE 231
           S  +P  QA  S  T   R+T      P    S PP+       P +  P    LP  P 
Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD------SPPLQAP--LSLPASPP 468

Query: 232 DIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEK-----EPPGQLQVK------AQPQA 280
                    +P   P     L A    +S  P         PP + Q          P A
Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA 528

Query: 281 RMTVPKQTQTPDLLPEALEAQVLPRFQPRV----------LQVQAQVQSQTQPRIPST-- 328
            +T P     P L P  L+    P   P +          LQ      +   P  PS+  
Sbjct: 529 SLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA 588

Query: 329 -------DTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL---QQEAEPQKQVQPQVHTQA 378
                       P LQ       SP  L     Q  P L     +A P     P +   A
Sbjct: 589 TPPPQAPPALASPPLQGLPSPPLSP--LATPPPQAPPXLALPPLQAPPSPPASPPLSPLA 646

Query: 379 QPSVQ---------------PQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVH 423
            PS Q               P   PP Q    PP      P   P      P Q P  + 
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP------PSQAPPSLA 700

Query: 424 VCGLEMPP 431
              L++PP
Sbjct: 701 APPLQVPP 708



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 74/302 (24%), Positives = 102/302 (33%), Gaps = 40/302 (13%)

Query: 162 PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTP 221
           P PV  P   S     G   QK  R S+  T  R        ++ P+ S  +A  R DT 
Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA-----TEAPKRSALSAGARRDTS 165

Query: 222 EDQDLPPCPEDIAKEKRT---------PAPEPEPCEASELPAKRLRSSEE--PTEKEPPG 270
                 P P  +A+  R          PAP   P   +E P K + S+ E   TE  P  
Sbjct: 166 GPTPGTPSPA-MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 224

Query: 271 QLQVKA-----QPQARMTVPKQTQTPDLLPEALEAQVLPR-----FQPRVLQVQAQVQSQ 320
           + +  A     +P +R      T           A+  PR      QP+   +QA    Q
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284

Query: 321 -TQPR---------IPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQV 370
            T PR         + S+          +A+    P++         P     A P    
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLA 344

Query: 371 QPQVHTQAQPSVQPQEHPPAQVSVQ-PPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEM 429
            P     A PS+Q    PPA    Q PP  T       P +  + P Q P  +    L+ 
Sbjct: 345 PPS--PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402

Query: 430 PP 431
           PP
Sbjct: 403 PP 404



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 55/227 (24%), Positives = 74/227 (32%), Gaps = 64/227 (28%)

Query: 46  PPQAPLPMAVSR-GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPP 104
           PPQAP P+A     +PP  P  P ++   T    +              L       +PP
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV------------PPLLAAPPLQVPP 770

Query: 105 ATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164
           +         P A+L         SP    P   PP LATP LQ           L  PP
Sbjct: 771 S---------PPASLP-------MSPLAKPPPQAPPALATPPLQ----------ALPSPP 804

Query: 165 VGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQ 224
              P   + F+ S   P      S   TP            PP+     A P +  P   
Sbjct: 805 ASFP-GQAPFSPSASLPM-----SPLATP------------PPQAPPVLAAPLLQVPPS- 845

Query: 225 DLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQ 271
             PP    +   +R P P P+    + +   RL  +  P    PP +
Sbjct: 846 --PPASPTLQAPRRPPTPGPD----TSVSGPRLTLALAPGPPPPPSR 886



 Score = 33.9 bits (76), Expect = 0.64
 Identities = 87/322 (27%), Positives = 107/322 (33%), Gaps = 88/322 (27%)

Query: 42   LQQSP-PQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQF 100
            LQ  P P A LPM+     PPQ P                       AL    LQ L   
Sbjct: 766  LQVPPSPPASLPMSPLAKPPPQAPP----------------------ALATPPLQALPS- 802

Query: 101  AMPPATYDTAGLTMPTATLGN---LRGYGMASPGLAAPSL----TPPQLAT--------- 144
              PPA++       P+A+L           A P LAAP L    +PP   T         
Sbjct: 803  --PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860

Query: 145  --PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSST-TPNRKTMPVE 201
              P+     P+ T     GPPP   P       LSG  P     +SS+T TP      + 
Sbjct: 861  PGPDTSVSGPRLTLALAPGPPP--PPSRSPSSTLSG--PDLAGHSSSATSTPEE----LR 912

Query: 202  DKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP---------EPEPCEASEL 252
                 PEG   AA P    P D +L  C    A   R PAP          P P   +  
Sbjct: 913  GYDSGPEGG-AAASP----PPDAELAACHP--AAWSRGPAPPLAFRGAPGAPLPWPPATG 965

Query: 253  PAK-----RLRSSEEPTEKEP-PGQLQVKAQP-------------QARMTVPKQTQTPDL 293
            P        +  +E P    P PG L     P              A    PKQ +  +L
Sbjct: 966  PGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGEL 1025

Query: 294  LPEALEAQVLPRFQPRVLQVQA 315
               AL+A V+     R L + A
Sbjct: 1026 PLGALQASVVQHLLSRTLLLAA 1047


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 48/108 (44%), Positives = 51/108 (47%), Gaps = 20/108 (18%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQL--------------QQQQLQQQQLLQLQQLLQQSPPQA 49
            QQQQQQ QQQQQQ QQ QQQQ               QQQQ QQQQ  Q QQ  QQ   Q 
Sbjct: 2056 QQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQ 2115

Query: 50   PLPMAVSRGLPPQ-QPQ-QPLLNLQGTNSASLLNGSMLQRALLLQQLQ 95
                   +  PPQ QPQ QP    QG            Q A L++QLQ
Sbjct: 2116 HQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQ----QQQQTAALVRQLQ 2159



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 57/206 (27%), Positives = 81/206 (39%), Gaps = 13/206 (6%)

Query: 224  QDLPPCPEDIAKEKRT-PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 282
            Q   P    +  ++ T PA    P   S  P +    S  PT  +P   LQ +       
Sbjct: 1942 QGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQ 2001

Query: 283  TVPKQ----TQTPDLLPEALE-AQVLPRFQPRVLQ-VQAQVQSQT----QPRIPSTDTQV 332
              P      T T     + L+   ++    P   Q VQA V+S      Q +      Q 
Sbjct: 2002 QAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQ 2061

Query: 333  QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 392
            Q + Q+Q Q Q   ++ + QQ+Q Q   QQ+ + Q+Q Q Q   Q Q   Q Q+H   Q 
Sbjct: 2062 QQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQ 2121

Query: 393  SVQPPEQTHEQPHTQPQVSLLAPEQT 418
                P Q   QP +QPQ      +QT
Sbjct: 2122 QQAAPPQP--QPQSQPQFQRQGLQQT 2145



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 43/144 (29%), Positives = 62/144 (43%), Gaps = 11/144 (7%)

Query: 278  PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV----- 332
            P +   V    ++  +LPE  + Q   + Q +  Q Q Q Q Q Q  I     Q      
Sbjct: 2032 PMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQ 2091

Query: 333  -QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA---EPQKQVQPQVHTQAQPSVQPQEHP 388
             Q + Q+Q Q Q   +    QQ+Q Q Q QQ+A   +PQ Q QPQ   Q     Q Q+  
Sbjct: 2092 QQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQT 2151

Query: 389  PAQVSVQPPEQTHEQPHTQPQVSL 412
             A V     + ++ QP  QP  ++
Sbjct: 2152 AALVRQLQQQLSNTQP--QPSTNI 2173



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 35/74 (47%), Positives = 38/74 (51%), Gaps = 5/74 (6%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ----QLLQQSPPQAPLPMAVSRGL 59
            QQQQQQ QQQQQQ QQ QQQQ    Q Q Q   Q Q    Q  QQ    A L   + + L
Sbjct: 2103 QQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQL 2162

Query: 60   PPQQPQQPLLNLQG 73
               QP QP  N+ G
Sbjct: 2163 SNTQP-QPSTNIFG 2175



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 27/57 (47%), Positives = 30/57 (52%)

Query: 10   LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQ 66
            L +QQQQ QQ QQQQ QQQQ QQQQ  Q   + QQ   Q        +    QQ QQ
Sbjct: 2048 LPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQ 2104



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/137 (29%), Positives = 60/137 (43%), Gaps = 20/137 (14%)

Query: 257  LRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQ 316
            +RS+    E++   Q Q + Q Q +    +Q Q    + +  + Q+L + Q +  Q Q Q
Sbjct: 2042 VRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQ 2101

Query: 317  VQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQV-- 374
             Q Q Q +      Q Q + Q+Q Q Q +P      Q Q QPQ Q++   Q Q Q Q   
Sbjct: 2102 QQQQQQQQ-----QQQQQQHQQQQQQQAAPPQ---PQPQSQPQFQRQGLQQTQQQQQTAA 2153

Query: 375  ----------HTQAQPS 381
                      +TQ QPS
Sbjct: 2154 LVRQLQQQLSNTQPQPS 2170



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 62/243 (25%), Positives = 91/243 (37%), Gaps = 58/243 (23%)

Query: 215  EPRMDTPEDQDLPPCPEDIAKEKRTPAP---------EPEPCEASELPAKRLRSSEEPTE 265
            EP    PED++ PP P  +  EK+ P P          P   E  +   K  + S+  T+
Sbjct: 1740 EPLPLPPEDEE-PPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATK 1798

Query: 266  KEPPGQLQVKAQPQARMTVPKQTQTPDLL----PEAL--------------EAQVLPRFQ 307
             E  G    ++ P   +TVP     PDLL    P ++              + Q LP   
Sbjct: 1799 TEDYGMGPGRSGPYG-VTVP-----PDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGG 1852

Query: 308  PRV-------LQVQAQVQSQTQPRI-PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 359
            PRV       L +Q      T P + P+T T V        +T           +Q QP 
Sbjct: 1853 PRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSV--------YRQQQPA 1904

Query: 360  LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ-----PPEQTHE--QPHTQPQVSL 412
            + Q    ++Q+Q       Q SV  Q  P +   +Q      P  +H   Q HT P  ++
Sbjct: 1905 VPQGQRLRQQLQQSQGMLGQSSVH-QMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTM 1963

Query: 413  LAP 415
            + P
Sbjct: 1964 VPP 1966


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,310,703
Number of Sequences: 37866
Number of extensions: 2417780
Number of successful extensions: 45286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 541
Number of HSP's successfully gapped in prelim test: 1031
Number of HSP's that attempted gapping in prelim test: 19704
Number of HSP's gapped (non-prelim): 13079
length of query: 837
length of database: 18,247,518
effective HSP length: 111
effective length of query: 726
effective length of database: 14,044,392
effective search space: 10196228592
effective search space used: 10196228592
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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