Guide to the Human Genome
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Search of human proteins with 196114949

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|196114949 hypothetical protein LOC23240 isoform 1 [Homo
sapiens]
         (1610 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|196114949 hypothetical protein LOC23240 isoform 1 [Homo sapiens]  3297   0.0  
gi|187608809 hypothetical protein LOC23240 isoform 2 [Homo sapiens]  3291   0.0  
gi|150456424 RW1 protein [Homo sapiens]                               254   5e-67
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    44   0.001
gi|55741677 SET domain containing 1A [Homo sapiens]                    40   0.018
gi|7662018 PHD finger protein 3 [Homo sapiens]                         39   0.053
gi|213385278 TNF receptor-associated factor 3 interacting protei...    37   0.12 
gi|87299628 biorientation of chromosomes in cell division 1-like...    37   0.15 
gi|62988361 absent in melanoma 1 [Homo sapiens]                        37   0.15 
gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]         37   0.20 
gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]         37   0.20 
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    37   0.20 
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    37   0.20 
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    37   0.20 
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    37   0.20 
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    37   0.20 
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    37   0.20 
gi|157785548 PAS domain containing 1 [Homo sapiens]                    37   0.20 
gi|15559211 RE1-silencing transcription factor [Homo sapiens]          36   0.26 
gi|171543895 ataxin 2 [Homo sapiens]                                   36   0.26 
gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]     36   0.26 
gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]      36   0.26 
gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap...    36   0.26 
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            36   0.34 
gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens]                  36   0.34 
gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens]                  36   0.34 
gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens]                  36   0.34 
gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens]                   36   0.34 
gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens]                   36   0.34 
gi|161702986 ezrin [Homo sapiens]                                      35   0.45 

>gi|196114949 hypothetical protein LOC23240 isoform 1 [Homo sapiens]
          Length = 1610

 Score = 3297 bits (8548), Expect = 0.0
 Identities = 1610/1610 (100%), Positives = 1610/1610 (100%)

Query: 1    MAGLRRPQPGCYCRTAAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGEL 60
            MAGLRRPQPGCYCRTAAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGEL
Sbjct: 1    MAGLRRPQPGCYCRTAAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGEL 60

Query: 61   LLPTQGDSEEGLEEPSQEQSFSDKLFSGKGLHFQPSVLDFGIQFLGHPVAKILHAYNPSR 120
            LLPTQGDSEEGLEEPSQEQSFSDKLFSGKGLHFQPSVLDFGIQFLGHPVAKILHAYNPSR
Sbjct: 61   LLPTQGDSEEGLEEPSQEQSFSDKLFSGKGLHFQPSVLDFGIQFLGHPVAKILHAYNPSR 120

Query: 121  DSEVVVNSVFAAAGHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVL 180
            DSEVVVNSVFAAAGHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVL
Sbjct: 121  DSEVVVNSVFAAAGHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVL 180

Query: 181  SYHVSGIGTRRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNK 240
            SYHVSGIGTRRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNK
Sbjct: 181  SYHVSGIGTRRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNK 240

Query: 241  VCQQLKGCYLESDDVLRLQMSIMVTMENFSKEFEENTQHLLDHLSIVYVATDESETSDDS 300
            VCQQLKGCYLESDDVLRLQMSIMVTMENFSKEFEENTQHLLDHLSIVYVATDESETSDDS
Sbjct: 241  VCQQLKGCYLESDDVLRLQMSIMVTMENFSKEFEENTQHLLDHLSIVYVATDESETSDDS 300

Query: 301  AVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNFTKIASFTCKAATSCDS 360
            AVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNFTKIASFTCKAATSCDS
Sbjct: 301  AVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNFTKIASFTCKAATSCDS 360

Query: 361  GIIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIETHENTSGLWSIWYRNHFDRS 420
            GIIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIETHENTSGLWSIWYRNHFDRS
Sbjct: 361  GIIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIETHENTSGLWSIWYRNHFDRS 420

Query: 421  VVLNDVFLSKETKHMLKILNFTGPLFLPPGCWNIFSLKLAVKDIAINLFTNVFLTTNIGA 480
            VVLNDVFLSKETKHMLKILNFTGPLFLPPGCWNIFSLKLAVKDIAINLFTNVFLTTNIGA
Sbjct: 421  VVLNDVFLSKETKHMLKILNFTGPLFLPPGCWNIFSLKLAVKDIAINLFTNVFLTTNIGA 480

Query: 481  IFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAGNPNWNGSLSLDQSTWNVDSELA 540
            IFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAGNPNWNGSLSLDQSTWNVDSELA
Sbjct: 481  IFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAGNPNWNGSLSLDQSTWNVDSELA 540

Query: 541  NKLYERWKKYKNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATAL 600
            NKLYERWKKYKNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATAL
Sbjct: 541  NKLYERWKKYKNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATAL 600

Query: 601  RSRMIKYFVVQNPSSWPVSLQLLPLSLYPKPEALVHLLHRWFGTDMQMINFTTGEFQLTE 660
            RSRMIKYFVVQNPSSWPVSLQLLPLSLYPKPEALVHLLHRWFGTDMQMINFTTGEFQLTE
Sbjct: 601  RSRMIKYFVVQNPSSWPVSLQLLPLSLYPKPEALVHLLHRWFGTDMQMINFTTGEFQLTE 660

Query: 661  ACPYLGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVE 720
            ACPYLGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVE
Sbjct: 661  ACPYLGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVE 720

Query: 721  GFGARELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPI 780
            GFGARELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPI
Sbjct: 721  GFGARELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPI 780

Query: 781  TVSSLKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADL 840
            TVSSLKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADL
Sbjct: 781  TVSSLKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADL 840

Query: 841  EFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILME 900
            EFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILME
Sbjct: 841  EFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILME 900

Query: 901  FMKTRQRQNASSSSQQNNGPMDVISPHSYKSNCKNFLDTYGPSDKGRGKNCLPVNTPQSR 960
            FMKTRQRQNASSSSQQNNGPMDVISPHSYKSNCKNFLDTYGPSDKGRGKNCLPVNTPQSR
Sbjct: 901  FMKTRQRQNASSSSQQNNGPMDVISPHSYKSNCKNFLDTYGPSDKGRGKNCLPVNTPQSR 960

Query: 961  IQNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLPAAKED 1020
            IQNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLPAAKED
Sbjct: 961  IQNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLPAAKED 1020

Query: 1021 ICTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGI 1080
            ICTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGI
Sbjct: 1021 ICTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGI 1080

Query: 1081 QTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNG 1140
            QTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNG
Sbjct: 1081 QTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNG 1140

Query: 1141 NNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQ 1200
            NNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQ
Sbjct: 1141 NNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQ 1200

Query: 1201 EKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWC 1260
            EKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWC
Sbjct: 1201 EKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWC 1260

Query: 1261 IQESTREVCKADAEIASSLPAAQREAEGYYQKPEKKCVDKFCSDSSSDCGSSSGSVRASR 1320
            IQESTREVCKADAEIASSLPAAQREAEGYYQKPEKKCVDKFCSDSSSDCGSSSGSVRASR
Sbjct: 1261 IQESTREVCKADAEIASSLPAAQREAEGYYQKPEKKCVDKFCSDSSSDCGSSSGSVRASR 1320

Query: 1321 GSWGSWSSTSSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMTVNSL 1380
            GSWGSWSSTSSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMTVNSL
Sbjct: 1321 GSWGSWSSTSSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMTVNSL 1380

Query: 1381 PQYAEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPPVCVTSSLNCTLENGVPCVIQESAPV 1440
            PQYAEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPPVCVTSSLNCTLENGVPCVIQESAPV
Sbjct: 1381 PQYAEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPPVCVTSSLNCTLENGVPCVIQESAPV 1440

Query: 1441 HNSFIDWSATCEGQFSSAYCPLELNDYNAFPEENMNYANGFPCPADVQTDFIDHNSQSTW 1500
            HNSFIDWSATCEGQFSSAYCPLELNDYNAFPEENMNYANGFPCPADVQTDFIDHNSQSTW
Sbjct: 1441 HNSFIDWSATCEGQFSSAYCPLELNDYNAFPEENMNYANGFPCPADVQTDFIDHNSQSTW 1500

Query: 1501 NTPPNMPAAWGHASFISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPINPTTEHST 1560
            NTPPNMPAAWGHASFISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPINPTTEHST
Sbjct: 1501 NTPPNMPAAWGHASFISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPINPTTEHST 1560

Query: 1561 HMENQAVVCKEYYPGFNPFRAYMNLDIWTTTANRNANFPLSRDSSYCGNV 1610
            HMENQAVVCKEYYPGFNPFRAYMNLDIWTTTANRNANFPLSRDSSYCGNV
Sbjct: 1561 HMENQAVVCKEYYPGFNPFRAYMNLDIWTTTANRNANFPLSRDSSYCGNV 1610


>gi|187608809 hypothetical protein LOC23240 isoform 2 [Homo sapiens]
          Length = 1609

 Score = 3291 bits (8532), Expect = 0.0
 Identities = 1609/1610 (99%), Positives = 1609/1610 (99%), Gaps = 1/1610 (0%)

Query: 1    MAGLRRPQPGCYCRTAAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGEL 60
            MAGLRRPQPGCYCRTAAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGEL
Sbjct: 1    MAGLRRPQPGCYCRTAAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGEL 60

Query: 61   LLPTQGDSEEGLEEPSQEQSFSDKLFSGKGLHFQPSVLDFGIQFLGHPVAKILHAYNPSR 120
            LLPTQGDSEEGLEEPSQEQSFSDKLFSGKGLHFQPSVLDFGIQFLGHPVAKILHAYNPSR
Sbjct: 61   LLPTQGDSEEGLEEPSQEQSFSDKLFSGKGLHFQPSVLDFGIQFLGHPVAKILHAYNPSR 120

Query: 121  DSEVVVNSVFAAAGHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVL 180
            DSEVVVNSVFAAAGHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVL
Sbjct: 121  DSEVVVNSVFAAAGHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVL 180

Query: 181  SYHVSGIGTRRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNK 240
            SYHVSGIGTRRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNK
Sbjct: 181  SYHVSGIGTRRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNK 240

Query: 241  VCQQLKGCYLESDDVLRLQMSIMVTMENFSKEFEENTQHLLDHLSIVYVATDESETSDDS 300
            VCQQLKGCYLESDDVLRLQMSIMVTMENFSKEFEENTQHLLDHLSIVYVATDESETSDDS
Sbjct: 241  VCQQLKGCYLESDDVLRLQMSIMVTMENFSKEFEENTQHLLDHLSIVYVATDESETSDDS 300

Query: 301  AVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNFTKIASFTCKAATSCDS 360
            AVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNFTKIASFTCKA TSCDS
Sbjct: 301  AVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNFTKIASFTCKA-TSCDS 359

Query: 361  GIIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIETHENTSGLWSIWYRNHFDRS 420
            GIIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIETHENTSGLWSIWYRNHFDRS
Sbjct: 360  GIIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIETHENTSGLWSIWYRNHFDRS 419

Query: 421  VVLNDVFLSKETKHMLKILNFTGPLFLPPGCWNIFSLKLAVKDIAINLFTNVFLTTNIGA 480
            VVLNDVFLSKETKHMLKILNFTGPLFLPPGCWNIFSLKLAVKDIAINLFTNVFLTTNIGA
Sbjct: 420  VVLNDVFLSKETKHMLKILNFTGPLFLPPGCWNIFSLKLAVKDIAINLFTNVFLTTNIGA 479

Query: 481  IFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAGNPNWNGSLSLDQSTWNVDSELA 540
            IFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAGNPNWNGSLSLDQSTWNVDSELA
Sbjct: 480  IFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAGNPNWNGSLSLDQSTWNVDSELA 539

Query: 541  NKLYERWKKYKNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATAL 600
            NKLYERWKKYKNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATAL
Sbjct: 540  NKLYERWKKYKNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATAL 599

Query: 601  RSRMIKYFVVQNPSSWPVSLQLLPLSLYPKPEALVHLLHRWFGTDMQMINFTTGEFQLTE 660
            RSRMIKYFVVQNPSSWPVSLQLLPLSLYPKPEALVHLLHRWFGTDMQMINFTTGEFQLTE
Sbjct: 600  RSRMIKYFVVQNPSSWPVSLQLLPLSLYPKPEALVHLLHRWFGTDMQMINFTTGEFQLTE 659

Query: 661  ACPYLGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVE 720
            ACPYLGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVE
Sbjct: 660  ACPYLGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVE 719

Query: 721  GFGARELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPI 780
            GFGARELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPI
Sbjct: 720  GFGARELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPI 779

Query: 781  TVSSLKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADL 840
            TVSSLKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADL
Sbjct: 780  TVSSLKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADL 839

Query: 841  EFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILME 900
            EFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILME
Sbjct: 840  EFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILME 899

Query: 901  FMKTRQRQNASSSSQQNNGPMDVISPHSYKSNCKNFLDTYGPSDKGRGKNCLPVNTPQSR 960
            FMKTRQRQNASSSSQQNNGPMDVISPHSYKSNCKNFLDTYGPSDKGRGKNCLPVNTPQSR
Sbjct: 900  FMKTRQRQNASSSSQQNNGPMDVISPHSYKSNCKNFLDTYGPSDKGRGKNCLPVNTPQSR 959

Query: 961  IQNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLPAAKED 1020
            IQNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLPAAKED
Sbjct: 960  IQNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLPAAKED 1019

Query: 1021 ICTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGI 1080
            ICTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGI
Sbjct: 1020 ICTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGI 1079

Query: 1081 QTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNG 1140
            QTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNG
Sbjct: 1080 QTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNG 1139

Query: 1141 NNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQ 1200
            NNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQ
Sbjct: 1140 NNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQ 1199

Query: 1201 EKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWC 1260
            EKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWC
Sbjct: 1200 EKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWC 1259

Query: 1261 IQESTREVCKADAEIASSLPAAQREAEGYYQKPEKKCVDKFCSDSSSDCGSSSGSVRASR 1320
            IQESTREVCKADAEIASSLPAAQREAEGYYQKPEKKCVDKFCSDSSSDCGSSSGSVRASR
Sbjct: 1260 IQESTREVCKADAEIASSLPAAQREAEGYYQKPEKKCVDKFCSDSSSDCGSSSGSVRASR 1319

Query: 1321 GSWGSWSSTSSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMTVNSL 1380
            GSWGSWSSTSSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMTVNSL
Sbjct: 1320 GSWGSWSSTSSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMTVNSL 1379

Query: 1381 PQYAEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPPVCVTSSLNCTLENGVPCVIQESAPV 1440
            PQYAEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPPVCVTSSLNCTLENGVPCVIQESAPV
Sbjct: 1380 PQYAEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPPVCVTSSLNCTLENGVPCVIQESAPV 1439

Query: 1441 HNSFIDWSATCEGQFSSAYCPLELNDYNAFPEENMNYANGFPCPADVQTDFIDHNSQSTW 1500
            HNSFIDWSATCEGQFSSAYCPLELNDYNAFPEENMNYANGFPCPADVQTDFIDHNSQSTW
Sbjct: 1440 HNSFIDWSATCEGQFSSAYCPLELNDYNAFPEENMNYANGFPCPADVQTDFIDHNSQSTW 1499

Query: 1501 NTPPNMPAAWGHASFISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPINPTTEHST 1560
            NTPPNMPAAWGHASFISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPINPTTEHST
Sbjct: 1500 NTPPNMPAAWGHASFISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPINPTTEHST 1559

Query: 1561 HMENQAVVCKEYYPGFNPFRAYMNLDIWTTTANRNANFPLSRDSSYCGNV 1610
            HMENQAVVCKEYYPGFNPFRAYMNLDIWTTTANRNANFPLSRDSSYCGNV
Sbjct: 1560 HMENQAVVCKEYYPGFNPFRAYMNLDIWTTTANRNANFPLSRDSSYCGNV 1609


>gi|150456424 RW1 protein [Homo sapiens]
          Length = 1883

 Score =  254 bits (649), Expect = 5e-67
 Identities = 178/547 (32%), Positives = 272/547 (49%), Gaps = 47/547 (8%)

Query: 493  TKEGSLGFEVIAHCGMHYFMGKS--KAGNPNWNGSLSLDQSTWNVDSELANKLYERWKKY 550
            +K  ++ F+    CG H ++G        P     +++ +  W+ D +L   L++ W   
Sbjct: 735  SKIANIYFDPGLQCGDHCYVGLPFLSKSEPKVQPGVAMQEDMWDADWDLHQSLFKGWTGI 794

Query: 551  KNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATALRSRMIKYFVV 610
            K     + + +        K      +     P +++ P   L F  T       +   +
Sbjct: 795  KENSGHRLSAIFEVNTDLQKNIISKITAELSWPSILSSPR-HLKFPLTNTNCSSEEEITL 853

Query: 611  QNPSSWPVSLQLLPLSLYPKPEALVH-LLHRWFGTDMQMINFTTGEFQLTEACPY----- 664
            +NP+  PV +Q +PL+LY  P   V  L+ R+  + +  I+  T EFQ+     +     
Sbjct: 854  ENPADVPVYVQFIPLALYSNPSVFVDKLVSRFNLSKVAKIDLRTLEFQVFRNSAHPLQSS 913

Query: 665  LGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVEGFGA 724
             G     SR  IL+L L+P E K V V FTP     V+SLI++RNNLTV+D + V+G G 
Sbjct: 914  TGFMEGLSRHLILNLILKPGEKKSVKVKFTPVHNRTVSSLIIVRNNLTVMDAVMVQGQGT 973

Query: 725  RELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPITVSS 784
             E L+V G+LPG G SLRFK+ E+ L DC   LK  +   ++ + FKVEN G L I + +
Sbjct: 974  TENLRVAGKLPGPGSSLRFKITEALLKDCTDSLKLREPNFTLKRTFKVENTGQLQIHIET 1033

Query: 785  LKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADLEFRF 844
            ++I+GY+C+GYGF+V++C +F+L  N SRDI I+FTPDFT+S VIR+L  +T +  EF F
Sbjct: 1034 IEISGYSCEGYGFKVVNCQEFTLSANASRDIIILFTPDFTASRVIRELKFITTSGSEFVF 1093

Query: 845  TLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKT 904
             LN +LP+H+L  CA+ +P P+WE + + +    +S   L VI  A+ +AQ I   F + 
Sbjct: 1094 ILNASLPYHMLATCAEALPRPNWELALYIIISGIMSALFLLVIGTAYLEAQGIWEPFRR- 1152

Query: 905  RQRQNASSSSQQNNGPMDVISPHSYK------------------SNCKNFLDTYGPSDK- 945
                    S + +N P DV  P   +                   + + F    G S + 
Sbjct: 1153 ------RLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLSCDPGHSRGFCGAGGSSSRP 1206

Query: 946  --GRGKNCLPVNTPQSRIQNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTE 1003
              G  K C P   P S   N   R+ A   + + K+  S   +  +TS  AASS S    
Sbjct: 1207 SAGSHKQCGPSVHPHSSHSN---RNSADVENVRAKNSSS---TSSRTSAQAASSQSA--- 1257

Query: 1004 EKQTSPL 1010
              +TSPL
Sbjct: 1258 -NKTSPL 1263



 Score =  150 bits (379), Expect = 1e-35
 Identities = 133/511 (26%), Positives = 238/511 (46%), Gaps = 48/511 (9%)

Query: 16  AAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGELLLPTQGDSEEGLEEP 75
           +AA  LL  +  V+        A+ +A     +++E+ + ++G LL   Q ++  GL   
Sbjct: 37  SAAAGLLGALHLVMTLVVAAARAEKEAFVQSESIIEVLRFDDGGLL---QTETTLGL--- 90

Query: 76  SQEQSFSDKLFSG--KGLHFQPSVLDFGIQFLGHPVAKILHAYNPSRDSEVVVNSVFAAA 133
           S  Q  S  L+ G  + + F+P +LDF  Q +G P  + ++ +NPS +  + + S+ A  
Sbjct: 91  SSYQQKSISLYRGNCRPIRFEPPMLDFHEQPVGMPKMEKVYLHNPSSEETITLVSISATT 150

Query: 134 GHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVLSYHVSGIGT---- 189
            HFH      R I   G TSF ++FL    G++E++LFINTS++GV +Y V G+G     
Sbjct: 151 SHFHASFFQNRKILPGGNTSFDVVFLARVVGNVENTLFINTSNHGVFTYQVFGVGVPNPY 210

Query: 190 -------RRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNKVC 242
                   R+    S   + N +   P  + +Q+ +M +   +   L ++L         
Sbjct: 211 RLRPFLGARVPVNSSFSPIINIH--NPHSEPLQVVEMYSSGGD---LHLELPTGQQGGTR 265

Query: 243 QQLKGCYLESDDVLRLQMSIM-----VTMENFSKEFEENTQHLLDHLSI-------VYVA 290
           +  +    E+  V+R   S                  ++T+ ++  + +       +Y +
Sbjct: 266 KLWEIPPYETKGVMRASFSSREADNHTAFIRIKTNASDSTEFIILPVEVEVTTAPGIYSS 325

Query: 291 TDESE-----TSD-DSAVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNF 344
           T+  +     T D    +N+++L+SG   + I  +R   Q DA+++ F+P+ L  S + +
Sbjct: 326 TEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPITLKASESKY 385

Query: 345 TKIASFTCKAA----TSCDSGIIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIE 400
           TK+AS +  A+     S  SG I    K      L+    + V  GY   D +AT FHI 
Sbjct: 386 TKVASISFDASKAKKPSQFSGKITVKAKEKSYSKLEIPYQAEVLDGYLGFDHAATLFHIR 445

Query: 401 THENTSGLWSIWYRNHFDRSVVLNDVFLSKETKHMLKILNFTGP-LFLPPGCWNIFSLKL 459
                     I+  N F  +++++DV L +E K M K+ NF+ P L LP     IF+L  
Sbjct: 446 DSPADPVERPIYLTNTFSFAILIHDVLLPEEAKTMFKVHNFSKPVLILPNESGYIFTLLF 505

Query: 460 AVKDIAINLFTNVFLTTNIGAIFAIPLQIYS 490
                ++++  N+ L TN  + F +P+++Y+
Sbjct: 506 MPSTSSMHIDNNILLITN-ASKFHLPVRVYT 535



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 89/400 (22%), Positives = 134/400 (33%), Gaps = 56/400 (14%)

Query: 1057 EENTLKNTIVFSNPSSECSMKEGIQTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPE 1116
            ++++   T   SNP +E  +KE  +     +    K     ++ K++    L   K++P 
Sbjct: 1419 DDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPT 1478

Query: 1117 NHLPRNSPQYHQPDLPEISRKNNGNNQQVPV--------KNEVDHCENLKKVDTKPSSEK 1168
            +  P +    + P L    R+N  +   +P         +N        K VD +P +  
Sbjct: 1479 DVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALA 1538

Query: 1169 KIHKTSRE-----DMFSEKQDIPFVEQEDPYRK--KKLQEKREGNLQNLNWSKSRTCRKN 1221
            K    S+E         EK   P      P  K         + +LQ LN   +    K 
Sbjct: 1539 KFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLN---ADIFLKQ 1595

Query: 1222 KKRGVAPVSRPPEQSDLKLVC----SDFERSELSSDINVRSWCIQESTREVCK-ADAEIA 1276
            ++    P S  P  +    V     S    S  SSD  ++      S  ++ K A     
Sbjct: 1596 RQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQ--PNGSKHKLTKAASLPGK 1653

Query: 1277 SSLPAAQREAEGYYQKPEKKCVDKFCSDS---SSDCGSSSGSVRA----SRGSWGSWSST 1329
            +  P       GY + P      K  S+    SS  G S   V +    S G W   S+ 
Sbjct: 1654 NGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNP 1713

Query: 1330 SSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMT------VNSLPQY 1383
            SS D           F   G+S    +   E    L LS + CN  +       NS P Y
Sbjct: 1714 SSPD-----FTPLNSFSAFGNSF---NLTGEVFSKLGLSRS-CNQASQRSWNEFNSGPSY 1764

Query: 1384 --------AEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPP 1415
                      PS P+    PT       L +   LW T P
Sbjct: 1765 LWESPATDPSPSWPASSGSPTHTATSV-LGNTSGLWSTTP 1803


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 55/208 (26%), Positives = 85/208 (40%), Gaps = 31/208 (14%)

Query: 1055 NKEENTLKNTIVFSNPSSECSMKEGIQTCMFPKETDIKTSENTAEFKERELCPLKTSKKL 1114
            N E +  KN+   S+PSS+             KE    TS++ +E  E  +    T+K  
Sbjct: 890  NSERDVTKNSKNDSHPSSD-------------KEEGEATSDSESEVSEIHIKVKPTTKSS 936

Query: 1115 PENHLP------RNSPQYHQPDLPEISRKNNGNNQQVPVKNEVDHCENLKKVDTKPSSEK 1168
                LP      ++S Q       E S  N+ NN+  P K++    ENLK+  TK   EK
Sbjct: 937  TNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEK 996

Query: 1169 ------KIHKT-SREDMFSEKQDIPFVEQEDPY--RKKKLQEKREGNLQNLNWSKSRTCR 1219
                  K HK   R+  F  +  + F E+E+     K+  QE +E  +   N +      
Sbjct: 997  LKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNIL 1056

Query: 1220 KNKKRGVAPVSRPPEQSDLKLVCSDFER 1247
            K +K     +S    + D   V SD ++
Sbjct: 1057 KTEKSSEEDLS---GKHDTVTVSSDLDQ 1081


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 40.0 bits (92), Expect = 0.018
 Identities = 52/211 (24%), Positives = 83/211 (39%), Gaps = 33/211 (15%)

Query: 1228 PVSRPPEQSD---------LKLVCSDFERSELSSDINVRSWCIQESTREVCKADAEIASS 1278
            P ++PP++ +          K    D E  E S + +       E   E  + D +   +
Sbjct: 937  PGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEK---DEEDDEEDEEDEDREEA 993

Query: 1279 LPAAQREAEGYYQKPEKKCVDKFCS---------DSSSDCGSSSGSVRASRGSWGSWSST 1329
            +   ++E E    + E+      CS         DS+SD  SSS S  +S  S  S SS+
Sbjct: 994  VDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSS 1053

Query: 1330 SSSDGDKKPMVDAQHFLPAG-DSVS----QNDFPSEAPISLNLSHNICNPMTVNSLPQYA 1384
            SSS  +     + +   PA   S S    +   P+ AP+ + +   +     V  LP+  
Sbjct: 1054 SSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAG-SPVTPLPE-- 1110

Query: 1385 EPSCPSLPAGPTGVEEDKGLYSPGDLWPTPP 1415
            + + P+ PAGPT          P    P PP
Sbjct: 1111 QEASPARPAGPTEESPPSAPLRP----PEPP 1137


>gi|7662018 PHD finger protein 3 [Homo sapiens]
          Length = 2039

 Score = 38.5 bits (88), Expect = 0.053
 Identities = 55/241 (22%), Positives = 93/241 (38%), Gaps = 43/241 (17%)

Query: 1188 VEQEDPYRKKKLQEKREGNLQNLNWSKSRTCRKNKKRG------------VAPVSRPPEQ 1235
            VE ++   K++LQE +E NLQ+   S S  CR N  +G            VA  +R P+ 
Sbjct: 1586 VESKEKTLKRQLQEDQENNLQDNQTSNSSPCRSNVGKGNIDGNVSCSENLVANTARSPQF 1645

Query: 1236 SDLKLVCSDFERSELSSDINVRSWCIQESTREVCKADAEIASSLPAAQREAEGYYQKPEK 1295
             +LK      + +  S  +        +S R   K        LP      E  +   + 
Sbjct: 1646 INLKR--DPRQAAGRSQPVTTSESKDGDSCRNGEK------HMLPGLSHNKE--HLTEQI 1695

Query: 1296 KCVDKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPM--------VDAQHFLP 1347
               +K CS   + C   S +++ ++ S    +  +S     KP+        ++  H   
Sbjct: 1696 NVEEKLCSAEKNSCVQQSDNLKVAQNSPSVENIQTSQAEQAKPLQEDILMQNIETVHPFR 1755

Query: 1348 AGDSVSQNDF------PSEAPI-SLNLSHNICNPMTVNSL----PQYAEPSCPSLPAGPT 1396
             G +V+ + F      PSE P  S+  +    +P T  +     PQ  +P+   L + P 
Sbjct: 1756 RGSAVATSHFEVGNTCPSEFPSKSITFTSRSTSPRTSTNFSPMRPQ--QPNLQHLKSSPP 1813

Query: 1397 G 1397
            G
Sbjct: 1814 G 1814


>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
            isoform 2 [Homo sapiens]
          Length = 625

 Score = 37.4 bits (85), Expect = 0.12
 Identities = 62/321 (19%), Positives = 125/321 (38%), Gaps = 57/321 (17%)

Query: 1051 KNLLNKEENTLKNTIVFSNPSSECSMKEGIQTCMFPKETDIKTSENTAEFKERELCPLKT 1110
            + +L  E+  +K     ++ S E   K         +E + +  +NT +  + E+    T
Sbjct: 126  RRVLAGEKGEVKGRASLTSRSQELDNKN-------VREEESRVHKNTEDRGDAEIKERST 178

Query: 1111 SKKLPENHLPRNSPQYHQPDLPEISRKNNGNNQQVPVKNEVDHCENLKKVDTKPSSEKKI 1170
            S+   +    +   +  + D  +   K NG N+    + E        K   +P +E++ 
Sbjct: 179  SRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERE------RAKARARPDNERQK 232

Query: 1171 HKTSREDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSKSRTCRKNKKRGVAPVS 1230
             + +RE               D  RKK+ + K EG  +     + R   +++ +G     
Sbjct: 233  DRGNRE------------RDRDSERKKETERKSEGGKEK-ERLRDRDRERDRDKG----- 274

Query: 1231 RPPEQSDLKLVCSDFERSELSSDINVRSWCIQESTREVCKADAEIASSLPAAQREAEGYY 1290
               +  D + V    +  E S D++      +E  RE  K + + ASS   +++ ++G +
Sbjct: 275  ---KDRDRRRV----KNGEHSWDLD------REKNREHDKPEKKSASSGEMSKKLSDGTF 321

Query: 1291 QKPEKKCVDKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPMVDAQHFLPAGD 1350
            +  + +   +  + +S    + +   R+     G   STS ++GD           PAG 
Sbjct: 322  KDSKAETETEISTRASKSLTTKTSKRRSKNSVEG--DSTSDAEGDAG---------PAGQ 370

Query: 1351 SVSQNDFPSEAPISLNLSHNI 1371
               +++ P    I   LS NI
Sbjct: 371  --DKSEVPETPEIPNELSSNI 389


>gi|87299628 biorientation of chromosomes in cell division 1-like
            [Homo sapiens]
          Length = 3051

 Score = 37.0 bits (84), Expect = 0.15
 Identities = 32/147 (21%), Positives = 67/147 (45%), Gaps = 5/147 (3%)

Query: 1155 ENLKKVDTKPSSEKKIHKTSR---EDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLN 1211
            EN KK        K+  KTS    ++  S  +++  V  +    K   +     ++ + N
Sbjct: 585  ENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDEN 644

Query: 1212 WSKSRTCRKNKKRGVAPVSRP--PEQSDLKLVCSDFERSELSSDINVRSWCIQESTREVC 1269
             ++S+  R++K+R   PV      E++D + V    ERSE+ ++   +     ++ + + 
Sbjct: 645  KNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLK 704

Query: 1270 KADAEIASSLPAAQREAEGYYQKPEKK 1296
            K D+E        ++E +   +KPE++
Sbjct: 705  KDDSETPHLKSLLKKEVKSSKEKPERE 731



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 62/295 (21%), Positives = 117/295 (39%), Gaps = 23/295 (7%)

Query: 912  SSSQQNNGPMDVISPHSYKSNCKNFLDTYGPSDKGRGKNCL------PVNTPQ---SRIQ 962
            SS +++N   + IS HS +++ K   +      K + K         P + P    SRI+
Sbjct: 2739 SSGRKDNA--EAISGHSVEADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSRIE 2796

Query: 963  NAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTEEK---QTSPLGSSLPAAKE 1019
             A ++ P T  H  K+          KTS+   S+TS   EEK    +S      P   +
Sbjct: 2797 TAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQND 2856

Query: 1020 DICTDAMRENW-ISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKE 1078
            D    +  E+  I ++   G      +   +   L  K+++     IV    S   S  +
Sbjct: 2857 DDTIKSQEEDQPIIIKRKRG----RPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLK 2912

Query: 1079 GIQTCMFPKETD--IKTSENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISR 1136
             +QT    KET    + S +  + +E+ +  ++   + P+  L  +     +   PE  R
Sbjct: 2913 VMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDA--ESSEPERKR 2970

Query: 1137 KNNGNNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSREDMFSEKQDIPFVEQE 1191
            + + ++     K +    E  ++ + +PS       T  E   S+ Q  P ++++
Sbjct: 2971 QKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQRSKTQLSPSIKRK 3025


>gi|62988361 absent in melanoma 1 [Homo sapiens]
          Length = 1723

 Score = 37.0 bits (84), Expect = 0.15
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 9/93 (9%)

Query: 1042 NLQKNLTLPKNL--LNKEENTLKNTIVFSNPSSECSMKEGIQTCMFPKETDIKTSENTAE 1099
            +++ NL  PKNL  L  E N     +   N +++ S+ E  +T   P+ TDI+   NT  
Sbjct: 239  HVELNLKTPKNLDSLGNEHNPFSQPVHKGNTATKISLFENKRTNSSPRHTDIRGQRNTPA 298

Query: 1100 FKE-----RELCPLKTSKKL--PENHLPRNSPQ 1125
              +      +L   K +K++  PE  +  NSPQ
Sbjct: 299  SSKTFVGRAKLNLAKKAKEMEQPEKKVMPNSPQ 331


>gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]
          Length = 1251

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 83/336 (24%), Positives = 118/336 (35%), Gaps = 70/336 (20%)

Query: 1163 KPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKL---------QEKREGN------- 1206
            K SSE  +H TS        + +P  + E    K KL         +E R G        
Sbjct: 277  KSSSETSVHCTSY-------RGVPASKPEPARAKAKLSKFSIPKQGEESRSGETNSCVEE 329

Query: 1207 -LQNLNWSKSRTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWCIQEST 1265
             ++ + W    +  +   + V P   P    D +LV S     +   D    S     S 
Sbjct: 330  IIREMTWLPPLSAIQAPGK-VEPTKFPFPNKDSQLVSSGHNNPK-KGDAEPESPDNGTSN 387

Query: 1266 REVCKADAEIASS-----LPAAQREA------EGYYQKPEKKCVDKFCSDSSSDCGSSSG 1314
              + + D +++S        AAQR A          Q+P   C     S   S   SSSG
Sbjct: 388  TSMLEDDLKLSSDEEENEQQAAQRTALRALSDSAVVQQPN--CRTSVPSSKGSSSSSSSG 445

Query: 1315 SVRASRGSWGSW-------SSTSSSDGDKKPMVDAQHFLPAGDSVSQND------FPSEA 1361
            S  +S  S  S        SS+S S+G K P   +    PA  +  Q D       P + 
Sbjct: 446  SSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVNPHKP 505

Query: 1362 PISL-NLSH-----NICNPM-----TVNSLPQYAEPSCPSLPAGPTGVEE------DKGL 1404
            PI + N SH        NP+         +P   +PS        T  EE      +K  
Sbjct: 506  PILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAP 565

Query: 1405 YSPGDLWPTPPVCVTSSLNCTL-ENGVPCVIQESAP 1439
             S G    +PP  V  +++       VPC   E+AP
Sbjct: 566  GSKGVKQKSPPAAVAVAVSAAAPPPAVPCAPAENAP 601



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 51/228 (22%), Positives = 87/228 (38%), Gaps = 18/228 (7%)

Query: 957  PQSRIQNAAKRSPATYGHSQKKHKC-SVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLP 1015
            P S IQ   K  P  +    K  +  S  ++  K   A   S    T    TS L   L 
Sbjct: 339  PLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDNGTSN--TSMLEDDLK 396

Query: 1016 AAKEDICTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECS 1075
             + ++   +       +LR  S   V  Q N     ++ + + ++  ++   S+ SS+  
Sbjct: 397  LSSDEEENEQQAAQRTALRALSDSAVVQQPNCRT--SVPSSKGSSSSSSSGSSSSSSDSE 454

Query: 1076 MKEGIQTCMFPKETDIKTSENTAE----FKERELCPLKTSKKLPENHLPRNSPQYHQPDL 1131
               G  +     ET+  +SE+       F   E  P  ++K   +  L + +P  H+P +
Sbjct: 455  SSSGSDS-----ETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVNP--HKPPI 507

Query: 1132 --PEISRKNNGNNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSRED 1177
                 S  +  N    PVK +V  C  +  V      EK+I  T +E+
Sbjct: 508  LIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEE 555


>gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]
          Length = 1226

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 83/336 (24%), Positives = 118/336 (35%), Gaps = 70/336 (20%)

Query: 1163 KPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKL---------QEKREGN------- 1206
            K SSE  +H TS        + +P  + E    K KL         +E R G        
Sbjct: 252  KSSSETSVHCTSY-------RGVPASKPEPARAKAKLSKFSIPKQGEESRSGETNSCVEE 304

Query: 1207 -LQNLNWSKSRTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWCIQEST 1265
             ++ + W    +  +   + V P   P    D +LV S     +   D    S     S 
Sbjct: 305  IIREMTWLPPLSAIQAPGK-VEPTKFPFPNKDSQLVSSGHNNPK-KGDAEPESPDNGTSN 362

Query: 1266 REVCKADAEIASS-----LPAAQREA------EGYYQKPEKKCVDKFCSDSSSDCGSSSG 1314
              + + D +++S        AAQR A          Q+P   C     S   S   SSSG
Sbjct: 363  TSMLEDDLKLSSDEEENEQQAAQRTALRALSDSAVVQQPN--CRTSVPSSKGSSSSSSSG 420

Query: 1315 SVRASRGSWGSW-------SSTSSSDGDKKPMVDAQHFLPAGDSVSQND------FPSEA 1361
            S  +S  S  S        SS+S S+G K P   +    PA  +  Q D       P + 
Sbjct: 421  SSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVNPHKP 480

Query: 1362 PISL-NLSH-----NICNPM-----TVNSLPQYAEPSCPSLPAGPTGVEE------DKGL 1404
            PI + N SH        NP+         +P   +PS        T  EE      +K  
Sbjct: 481  PILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAP 540

Query: 1405 YSPGDLWPTPPVCVTSSLNCTL-ENGVPCVIQESAP 1439
             S G    +PP  V  +++       VPC   E+AP
Sbjct: 541  GSKGVKQKSPPAAVAVAVSAAAPPPAVPCAPAENAP 576



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 51/228 (22%), Positives = 87/228 (38%), Gaps = 18/228 (7%)

Query: 957  PQSRIQNAAKRSPATYGHSQKKHKC-SVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLP 1015
            P S IQ   K  P  +    K  +  S  ++  K   A   S    T    TS L   L 
Sbjct: 314  PLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDNGTSN--TSMLEDDLK 371

Query: 1016 AAKEDICTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECS 1075
             + ++   +       +LR  S   V  Q N     ++ + + ++  ++   S+ SS+  
Sbjct: 372  LSSDEEENEQQAAQRTALRALSDSAVVQQPNCRT--SVPSSKGSSSSSSSGSSSSSSDSE 429

Query: 1076 MKEGIQTCMFPKETDIKTSENTAE----FKERELCPLKTSKKLPENHLPRNSPQYHQPDL 1131
               G  +     ET+  +SE+       F   E  P  ++K   +  L + +P  H+P +
Sbjct: 430  SSSGSDS-----ETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVNP--HKPPI 482

Query: 1132 --PEISRKNNGNNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSRED 1177
                 S  +  N    PVK +V  C  +  V      EK+I  T +E+
Sbjct: 483  LIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEE 530


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
            [Homo sapiens]
          Length = 1412

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 21/182 (11%)

Query: 1176 EDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQ 1235
            ED  S  ++    E+E P  K  LQ K  G    +  + S   +++ ++G AP   PP +
Sbjct: 260  EDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG-AASAPAKESPRKGAAPA--PPGK 316

Query: 1236 SDLKLVCSDF-ERSELSSDINVRSWCIQESTREV---CKADAEIASSLPAAQREAEGYYQ 1291
            +   +  +   +R E S   +  S   +E+  +     KA    A+S PA +   +G   
Sbjct: 317  TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 376

Query: 1292 KPEKKCVDKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPM--VDAQHFLPAG 1349
             P +K             G ++  V+  +    S SS+  SD D++ +  ++A    P G
Sbjct: 377  APPRK------------TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 424

Query: 1350 DS 1351
             S
Sbjct: 425  KS 426


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
            [Homo sapiens]
          Length = 1451

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 21/182 (11%)

Query: 1176 EDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQ 1235
            ED  S  ++    E+E P  K  LQ K  G    +  + S   +++ ++G AP   PP +
Sbjct: 337  EDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG-AASAPAKESPRKGAAPA--PPGK 393

Query: 1236 SDLKLVCSDF-ERSELSSDINVRSWCIQESTREV---CKADAEIASSLPAAQREAEGYYQ 1291
            +   +  +   +R E S   +  S   +E+  +     KA    A+S PA +   +G   
Sbjct: 394  TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 453

Query: 1292 KPEKKCVDKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPM--VDAQHFLPAG 1349
             P +K             G ++  V+  +    S SS+  SD D++ +  ++A    P G
Sbjct: 454  APPRK------------TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 501

Query: 1350 DS 1351
             S
Sbjct: 502  KS 503


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
            [Homo sapiens]
          Length = 1488

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 21/182 (11%)

Query: 1176 EDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQ 1235
            ED  S  ++    E+E P  K  LQ K  G    +  + S   +++ ++G AP   PP +
Sbjct: 337  EDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG-AASAPAKESPRKGAAPA--PPGK 393

Query: 1236 SDLKLVCSDF-ERSELSSDINVRSWCIQESTREV---CKADAEIASSLPAAQREAEGYYQ 1291
            +   +  +   +R E S   +  S   +E+  +     KA    A+S PA +   +G   
Sbjct: 394  TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 453

Query: 1292 KPEKKCVDKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPM--VDAQHFLPAG 1349
             P +K             G ++  V+  +    S SS+  SD D++ +  ++A    P G
Sbjct: 454  APPRK------------TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 501

Query: 1350 DS 1351
             S
Sbjct: 502  KS 503


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
            sapiens]
          Length = 1411

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 21/182 (11%)

Query: 1176 EDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQ 1235
            ED  S  ++    E+E P  K  LQ K  G    +  + S   +++ ++G AP   PP +
Sbjct: 260  EDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG-AASAPAKESPRKGAAPA--PPGK 316

Query: 1236 SDLKLVCSDF-ERSELSSDINVRSWCIQESTREV---CKADAEIASSLPAAQREAEGYYQ 1291
            +   +  +   +R E S   +  S   +E+  +     KA    A+S PA +   +G   
Sbjct: 317  TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 376

Query: 1292 KPEKKCVDKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPM--VDAQHFLPAG 1349
             P +K             G ++  V+  +    S SS+  SD D++ +  ++A    P G
Sbjct: 377  APPRK------------TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 424

Query: 1350 DS 1351
             S
Sbjct: 425  KS 426


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
            sapiens]
          Length = 1450

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 21/182 (11%)

Query: 1176 EDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQ 1235
            ED  S  ++    E+E P  K  LQ K  G    +  + S   +++ ++G AP   PP +
Sbjct: 337  EDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG-AASAPAKESPRKGAAPA--PPGK 393

Query: 1236 SDLKLVCSDF-ERSELSSDINVRSWCIQESTREV---CKADAEIASSLPAAQREAEGYYQ 1291
            +   +  +   +R E S   +  S   +E+  +     KA    A+S PA +   +G   
Sbjct: 394  TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 453

Query: 1292 KPEKKCVDKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPM--VDAQHFLPAG 1349
             P +K             G ++  V+  +    S SS+  SD D++ +  ++A    P G
Sbjct: 454  APPRK------------TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 501

Query: 1350 DS 1351
             S
Sbjct: 502  KS 503


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
            sapiens]
          Length = 958

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 21/182 (11%)

Query: 1176 EDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQ 1235
            ED  S  ++    E+E P  K  LQ K  G    +  + S   +++ ++G AP   PP +
Sbjct: 337  EDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG-AASAPAKESPRKGAAPA--PPGK 393

Query: 1236 SDLKLVCSDF-ERSELSSDINVRSWCIQESTREV---CKADAEIASSLPAAQREAEGYYQ 1291
            +   +  +   +R E S   +  S   +E+  +     KA    A+S PA +   +G   
Sbjct: 394  TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 453

Query: 1292 KPEKKCVDKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPM--VDAQHFLPAG 1349
             P +K             G ++  V+  +    S SS+  SD D++ +  ++A    P G
Sbjct: 454  APPRK------------TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 501

Query: 1350 DS 1351
             S
Sbjct: 502  KS 503


>gi|157785548 PAS domain containing 1 [Homo sapiens]
          Length = 773

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 57/269 (21%), Positives = 104/269 (38%), Gaps = 58/269 (21%)

Query: 1042 NLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKE------GIQTCMFPKETDIKTSE 1095
            N Q  L L  + L K+ NTL++ ++    SSE   K+      G      P   D+K   
Sbjct: 397  NQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKC-- 454

Query: 1096 NTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNGNNQQVPVKNEVDHCE 1155
                      C L  S  L      +N+ +  +P +          NQQ  V+ E    E
Sbjct: 455  ---------FCGLSLSNSL------KNTGELQEPCV--------AFNQQQLVQQEQHLKE 491

Query: 1156 NLKKVDTKPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSKS 1215
              +++  +    ++  K  ++    EK+ +   +++    KKKLQE+R          K 
Sbjct: 492  QQRQLREQLQQLREQRKVQKQKKMQEKKKL---QEQKMQEKKKLQEQRR--------QKK 540

Query: 1216 RTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWCIQ---ESTREV---- 1268
            +  ++ KK     + + PE+   K      +   L  ++ V +  +Q   ++ R+V    
Sbjct: 541  KKLQERKKWQGQMLQKEPEEEQQK---QQLQEQPLKHNVIVGNERVQICLQNPRDVSVPL 597

Query: 1269 CKADAEIASSLP------AAQREAEGYYQ 1291
            C        + P      AA+++  G+YQ
Sbjct: 598  CNHPVRFLQAQPIVPVQRAAEQQPSGFYQ 626


>gi|15559211 RE1-silencing transcription factor [Homo sapiens]
          Length = 1097

 Score = 36.2 bits (82), Expect = 0.26
 Identities = 67/309 (21%), Positives = 118/309 (38%), Gaps = 49/309 (15%)

Query: 901  FMKTRQRQNASSSSQQNNGPMDVISPHSYKSNCKNFLDTYGPSDKGRGKNCLPVNTPQSR 960
            ++ + Q +    + Q +NGP  +  PH            Y  +D+   K  + ++     
Sbjct: 339  YVASNQHEVTRHARQVHNGPKPLNCPHC----------DYKTADRSNFKKHVELHV---- 384

Query: 961  IQNAAKRSPATYGHSQKKHKCSVYY---SKHKT---STAAASSTSTTTEEKQTSPLGSSL 1014
              N  + +     ++  K KC++ Y   SKH T    T   S       +K+ + L  ++
Sbjct: 385  --NPRQFNCPVCDYAASK-KCNLQYHFKSKHPTCPNKTMDVSKVKLKKTKKREADLPDNI 441

Query: 1015 PAAKEDICTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFS-NPSSE 1073
               K +I      +  I    A   N   +K++   K  ++KE+    N  V      + 
Sbjct: 442  TNEKTEI-----EQTKIKGDVAGKKN---EKSVKAEKRDVSKEKKPSNNVSVIQVTTRTR 493

Query: 1074 CSMKEGIQTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPE 1133
             S+ E        KE D+ T  N+ +F + +    K        H P N  +       +
Sbjct: 494  KSVTE-------VKEMDVHTGSNSEKFSKTKKSKRKLEVDSHSLHGPVNDEESSTKKKKK 546

Query: 1134 ISRKNNGNNQQVPVKNEVDHCENLKKVDT--KPSSEKKIHKTSREDMFSEKQDIPFVEQE 1191
            +  K+  N+Q+VP  +     E  KK +T  K S++KK  K       S+K   P   Q+
Sbjct: 547  VESKSKNNSQEVPKGD--SKVEENKKQNTCMKKSTKKKTLKNKS----SKKSSKP--PQK 598

Query: 1192 DPYRKKKLQ 1200
            +P  K   Q
Sbjct: 599  EPVEKGSAQ 607


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score = 36.2 bits (82), Expect = 0.26
 Identities = 70/316 (22%), Positives = 113/316 (35%), Gaps = 42/316 (13%)

Query: 1119 LPRNSPQYHQPDLPEISRKNN-GNNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSRED 1177
            +PR SP+ H+P  P   R+N+ GN    PV           +    P         S   
Sbjct: 680  VPRLSPKTHRPRSP---RQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPA- 735

Query: 1178 MFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSK-SRTCRKNKKRGVAPV--SRPPE 1234
              S +   P  E +D   + + Q    GN +N+  ++ S +  K + +G++PV      +
Sbjct: 736  --SNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQ 793

Query: 1235 QSDLKLVCSDFERSELSSDINVRSWCIQESTREVCKADAEIASSLPAAQREAEGYYQKPE 1294
              DLK   +DF     S+          ES  ++   + E        ++  +    K E
Sbjct: 794  IDDLKKFKNDFRLQPSSTS---------ESMDQLLNKNRE-------GEKSRDLIKDKIE 837

Query: 1295 KKCVDKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPMVDAQHFLPA-----G 1349
                D F  +SSS+C S S    +   S    S+T    G +      Q   PA      
Sbjct: 838  PSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKD 897

Query: 1350 DSVSQNDFPSEAPIS-LNLSHNICNPMTVNSLPQYAEPSCPSLPA----------GPTGV 1398
            D   + D   +   S LN +    NP + +       P+ P   A           PT V
Sbjct: 898  DKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPV 957

Query: 1399 EEDKGLYSPGDLWPTP 1414
                  ++P  ++P P
Sbjct: 958  YTQPVCFAPNMMYPVP 973


>gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]
          Length = 2540

 Score = 36.2 bits (82), Expect = 0.26
 Identities = 62/274 (22%), Positives = 108/274 (39%), Gaps = 28/274 (10%)

Query: 983  VYYSKHKTSTAAA---SSTSTTTEEK--QTSPLGSSLPAAKEDICTDAMRENWISLRYAS 1037
            ++  KHK + AAA   SS ++ TE    +   L +SLP     IC+   + N +    AS
Sbjct: 1480 IHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQAS 1539

Query: 1038 GINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGIQTC----MFPKETDIKT 1093
              +     +  L K  L +     KNT    N  +  S+ E I+ C    +    +DI+ 
Sbjct: 1540 QTS-QPNYHTKLKKAWLTRHSEEDKNTNKMENSGN--SVSEIIKPCSVNLIASTSSDIQN 1596

Query: 1094 SENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNGNNQQVPV----KN 1149
            S ++    ++ +   K +++  +      S +    D  E   +     Q  P     +N
Sbjct: 1597 SVDSKIIVDKYVKDDKVNRRKAKRTYESGS-ESGDSDESESKSEQRTKRQPKPTYKKKQN 1655

Query: 1150 EVDHCENLKKVDTKPS---SEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQEKREGN 1206
            ++   +   + D KP+   S     ++  +   +    IP    +D  + KKL++  E  
Sbjct: 1656 DLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESF 1715

Query: 1207 LQN-------LNWSKSRTCRK-NKKRGVAPVSRP 1232
            LQ+        N  K R CR    K+G  P   P
Sbjct: 1716 LQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSP 1749


>gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]
          Length = 2303

 Score = 36.2 bits (82), Expect = 0.26
 Identities = 62/274 (22%), Positives = 108/274 (39%), Gaps = 28/274 (10%)

Query: 983  VYYSKHKTSTAAA---SSTSTTTEEK--QTSPLGSSLPAAKEDICTDAMRENWISLRYAS 1037
            ++  KHK + AAA   SS ++ TE    +   L +SLP     IC+   + N +    AS
Sbjct: 1261 IHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQAS 1320

Query: 1038 GINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGIQTC----MFPKETDIKT 1093
              +     +  L K  L +     KNT    N  +  S+ E I+ C    +    +DI+ 
Sbjct: 1321 QTS-QPNYHTKLKKAWLTRHSEEDKNTNKMENSGN--SVSEIIKPCSVNLIASTSSDIQN 1377

Query: 1094 SENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNGNNQQVPV----KN 1149
            S ++    ++ +   K +++  +      S +    D  E   +     Q  P     +N
Sbjct: 1378 SVDSKIIVDKYVKDDKVNRRKAKRTYESGS-ESGDSDESESKSEQRTKRQPKPTYKKKQN 1436

Query: 1150 EVDHCENLKKVDTKPS---SEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQEKREGN 1206
            ++   +   + D KP+   S     ++  +   +    IP    +D  + KKL++  E  
Sbjct: 1437 DLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESF 1496

Query: 1207 LQN-------LNWSKSRTCRK-NKKRGVAPVSRP 1232
            LQ+        N  K R CR    K+G  P   P
Sbjct: 1497 LQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSP 1530


>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sapiens]
          Length = 1555

 Score = 36.2 bits (82), Expect = 0.26
 Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 17/118 (14%)

Query: 1109 KTSKKLPENHLPRNSPQYHQPDLPEISRKNNGNNQQVPVKNEVDHCENLKKVDTK---PS 1165
            KTSK +P   L  NS           S++    + +   K E+D  ++  K  +K   P 
Sbjct: 328  KTSKTIPSEKL--NS-----------SKQEKSKSGEKITKKELDQLDSKSKSKSKSPSPL 374

Query: 1166 SEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSKSRTCRKNKK 1223
              K  H    ++  SE   +  + + DP  KK LQ+K +G   ++   K +T  K  K
Sbjct: 375  KNKLSHTKDLKNQESESMRLSDMNKRDPRLKKHLQDKTDGKDDDVK-EKRKTAEKKDK 431



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 73/324 (22%), Positives = 124/324 (38%), Gaps = 76/324 (23%)

Query: 924  ISPHSY---KSNCKNFL-DTYGPSDKGRGKNCLPVNTPQSRIQNAAKRSPATYGHSQKKH 979
            IS HS+   +S+ K FL +T   SD    K      T  S   N++K+  +  G    K 
Sbjct: 302  ISQHSHGKDQSHRKEFLMNTLNQSDTKTSK------TIPSEKLNSSKQEKSKSGEKITKK 355

Query: 980  KCSVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLPAAKEDICTDAMRENWISLRYASGI 1039
            +     SK K+ +            K  SPL + L   K+                    
Sbjct: 356  ELDQLDSKSKSKS------------KSPSPLKNKLSHTKD-------------------- 383

Query: 1040 NVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGIQTC-MFPKETDIKTSEN-- 1096
             +  Q++ ++  + +NK +  LK  +       +  +KE  +T     K+  +K+SE+  
Sbjct: 384  -LKNQESESMRLSDMNKRDPRLKKHLQDKTDGKDDDVKEKRKTAEKKDKDEHMKSSEHRL 442

Query: 1097 ------------------TAEFKERELCPLKTS-KKLPENHLPRN-SPQYHQPDLPEISR 1136
                              T E +++   P ++S +K   +  P++ SP  H P   +  R
Sbjct: 443  AGSRNKIINGIVQKQDTITEESEKQGTKPGRSSTRKRSRSRSPKSRSPIIHSPKRRD--R 500

Query: 1137 KNNGNNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSREDMF---SEKQDIPFVEQEDP 1193
            ++    Q+            +++   K S  ++    SRED     S KQDI      DP
Sbjct: 501  RSPKRRQRSMSPTSTPKAGKIRQSGAKQSHMEEFTPPSREDRNAKRSTKQDI-----RDP 555

Query: 1194 YRKKKLQEKREGNLQNLNWSKSRT 1217
             R KK +E+R     N + +KS T
Sbjct: 556  RRMKKTEEERPQETTNQHSTKSGT 579


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 35.8 bits (81), Expect = 0.34
 Identities = 30/116 (25%), Positives = 42/116 (36%), Gaps = 10/116 (8%)

Query: 1299 DKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPMVDAQHFLPAGDSVSQNDFP 1358
            D   SDS   C S+S +      S  SW+S  S  G   P V     L      S +   
Sbjct: 279  DSITSDSGWVCPSASWA-----SSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASG 333

Query: 1359 SEAPISLNLSHNICNPMTVNSLPQYAEPSCPSLPAGPTGVEEDKGLYSPGDLWPTP 1414
            + AP     + +  + ++  S   +A PS     A       D G  SP   W +P
Sbjct: 334  ASAPSDSGWTSHSASGVSTTSDSGWASPS-----ASGASTSSDSGWASPSASWASP 384


>gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens]
          Length = 1205

 Score = 35.8 bits (81), Expect = 0.34
 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 14/105 (13%)

Query: 1107 PLKTSKKLPENHLPRNSPQY--HQP-----DLPEISRKNNGNNQQVPVKNEVDHCENL-- 1157
            PL +    P+ HLP   P +   QP       P  S+ N       P+ N   H ++L  
Sbjct: 1030 PLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPT 1089

Query: 1158 KKVDTKP-SSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQE 1201
            KK+  KP   E  I KT+ ED+             DP  K+KL +
Sbjct: 1090 KKITKKPIPDEHLILKTTFEDLIQR----CLSSATDPQTKRKLDD 1130


>gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens]
          Length = 1220

 Score = 35.8 bits (81), Expect = 0.34
 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 14/105 (13%)

Query: 1107 PLKTSKKLPENHLPRNSPQY--HQP-----DLPEISRKNNGNNQQVPVKNEVDHCENL-- 1157
            PL +    P+ HLP   P +   QP       P  S+ N       P+ N   H ++L  
Sbjct: 1045 PLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPT 1104

Query: 1158 KKVDTKP-SSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQE 1201
            KK+  KP   E  I KT+ ED+             DP  K+KL +
Sbjct: 1105 KKITKKPIPDEHLILKTTFEDLIQR----CLSSATDPQTKRKLDD 1145


>gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens]
          Length = 1106

 Score = 35.8 bits (81), Expect = 0.34
 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 14/105 (13%)

Query: 1107 PLKTSKKLPENHLPRNSPQY--HQP-----DLPEISRKNNGNNQQVPVKNEVDHCENL-- 1157
            PL +    P+ HLP   P +   QP       P  S+ N       P+ N   H ++L  
Sbjct: 931  PLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPT 990

Query: 1158 KKVDTKP-SSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQE 1201
            KK+  KP   E  I KT+ ED+             DP  K+KL +
Sbjct: 991  KKITKKPIPDEHLILKTTFEDLIQR----CLSSATDPQTKRKLDD 1031


>gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens]
          Length = 1181

 Score = 35.8 bits (81), Expect = 0.34
 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 14/105 (13%)

Query: 1107 PLKTSKKLPENHLPRNSPQY--HQP-----DLPEISRKNNGNNQQVPVKNEVDHCENL-- 1157
            PL +    P+ HLP   P +   QP       P  S+ N       P+ N   H ++L  
Sbjct: 1006 PLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPT 1065

Query: 1158 KKVDTKP-SSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQE 1201
            KK+  KP   E  I KT+ ED+             DP  K+KL +
Sbjct: 1066 KKITKKPIPDEHLILKTTFEDLIQR----CLSSATDPQTKRKLDD 1106


>gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens]
          Length = 1220

 Score = 35.8 bits (81), Expect = 0.34
 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 14/105 (13%)

Query: 1107 PLKTSKKLPENHLPRNSPQY--HQP-----DLPEISRKNNGNNQQVPVKNEVDHCENL-- 1157
            PL +    P+ HLP   P +   QP       P  S+ N       P+ N   H ++L  
Sbjct: 1045 PLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPT 1104

Query: 1158 KKVDTKP-SSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQE 1201
            KK+  KP   E  I KT+ ED+             DP  K+KL +
Sbjct: 1105 KKITKKPIPDEHLILKTTFEDLIQR----CLSSATDPQTKRKLDD 1145


>gi|161702986 ezrin [Homo sapiens]
          Length = 586

 Score = 35.4 bits (80), Expect = 0.45
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 6/79 (7%)

Query: 507 GMHYFMGKSKAGNPNWNGSLSLDQSTWNVDSELANKLYERWKKYKNGDVCKRNVLGTTRF 566
           G++YF  K+K G   W G  +L  + +  D +L  K+   W + +N            +F
Sbjct: 202 GINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNIS------FNDKKF 255

Query: 567 AHLKKSKESESFVFFLPRL 585
                 K++  FVF+ PRL
Sbjct: 256 VIKPIDKKAPDFVFYAPRL 274


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,133,288
Number of Sequences: 37866
Number of extensions: 3194135
Number of successful extensions: 10565
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 10313
Number of HSP's gapped (non-prelim): 289
length of query: 1610
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1494
effective length of database: 13,855,062
effective search space: 20699462628
effective search space used: 20699462628
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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