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Search of human proteins with 195947382
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195947382 Rab interacting lysosomal protein-like 1 [Homo
sapiens]
(403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195947382 Rab interacting lysosomal protein-like 1 [Homo sapi... 790 0.0
gi|93204881 Rab interacting lysosomal protein [Homo sapiens] 130 3e-30
gi|21450828 Rab interacting lysosomal protein-like 2 [Homo sapiens] 77 2e-14
gi|71061468 centromere protein E [Homo sapiens] 69 1e-11
gi|45439327 periplakin [Homo sapiens] 66 6e-11
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 65 8e-11
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 62 1e-09
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 61 2e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 60 3e-09
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 60 3e-09
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 60 3e-09
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 60 3e-09
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 60 3e-09
gi|190194355 p90 autoantigen [Homo sapiens] 60 5e-09
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 60 5e-09
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 60 5e-09
gi|221219020 NYD-SP11 protein [Homo sapiens] 59 6e-09
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 6e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 59 6e-09
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 59 6e-09
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 59 6e-09
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 59 6e-09
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 59 6e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 59 1e-08
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 58 1e-08
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 58 2e-08
gi|33946313 ninein isoform 4 [Homo sapiens] 58 2e-08
gi|33946321 ninein isoform 5 [Homo sapiens] 58 2e-08
gi|148536871 ninein isoform 1 [Homo sapiens] 58 2e-08
gi|148536869 ninein isoform 2 [Homo sapiens] 58 2e-08
>gi|195947382 Rab interacting lysosomal protein-like 1 [Homo
sapiens]
Length = 403
Score = 790 bits (2040), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRV 60
MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRV
Sbjct: 1 MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRV 60
Query: 61 LEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLL 120
LEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLL
Sbjct: 61 LEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLL 120
Query: 121 SQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAK 180
SQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAK
Sbjct: 121 SQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAK 180
Query: 181 DRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEM 240
DRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEM
Sbjct: 181 DRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEM 240
Query: 241 GSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELR 300
GSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELR
Sbjct: 241 GSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELR 300
Query: 301 DVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFF 360
DVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFF
Sbjct: 301 DVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFF 360
Query: 361 SRDKKRLANTQRNVHIQESFGQWANTHRDDGYTEQGQEALQHL 403
SRDKKRLANTQRNVHIQESFGQWANTHRDDGYTEQGQEALQHL
Sbjct: 361 SRDKKRLANTQRNVHIQESFGQWANTHRDDGYTEQGQEALQHL 403
>gi|93204881 Rab interacting lysosomal protein [Homo sapiens]
Length = 401
Score = 130 bits (326), Expect = 3e-30
Identities = 106/339 (31%), Positives = 166/339 (48%), Gaps = 78/339 (23%)
Query: 6 GSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILE 65
GS AA SA + AEL VY +A +G E + + + G EA A L+P VVR LE+LE
Sbjct: 14 GSREAAGSA---SAAEL----VYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLE 66
Query: 66 VLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQ 125
V P D L++ AQ ++ +
Sbjct: 67 QAA----VGPAPDSLQVS--------------------------------AQPAEQELRR 90
Query: 126 LQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELG 185
L+EEN++L L + ER ++++LKEV D+QRDE+RA +R+L
Sbjct: 91 LREENERLRREL---------------RAGPQEERALLRQLKEVTDRQRDELRAHNRDLR 135
Query: 186 LKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRA 245
+ ++ EALQ+Q RL+ +N +LRH++ ++ Q +A D + + Q+ G A
Sbjct: 136 QRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRA--------AQDRERERQQPG--EA 185
Query: 246 ELGKLRERLQGEHSQNGE---EEPETEPVGEESISDAEKVAMDLKDPNRP------RFTL 296
+ +ER +G+ + G +EPE G + + E A + RP RF+
Sbjct: 186 ATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSR 245
Query: 297 QELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIP 335
+E +L ERNELK+KVFLL+EELAY++ E+ ++R+P
Sbjct: 246 EEFEQILQERNELKAKVFLLKEELAYFQ-RELLTDHRVP 283
>gi|21450828 Rab interacting lysosomal protein-like 2 [Homo sapiens]
Length = 211
Score = 77.4 bits (189), Expect = 2e-14
Identities = 61/161 (37%), Positives = 86/161 (53%), Gaps = 19/161 (11%)
Query: 171 DKQRDEIRAKDRELG-----LKNEDVEALQQQQTR-LMKINHDLRHRVTVVEAQGKALIE 224
D++RDE+ + LG L EDV + R LM + D RVT ++ + ++E
Sbjct: 17 DEERDEV-GPEGALGKSPFQLTAEDVYDISYLLGRELMALGSD--PRVTQLQFKVVRVLE 73
Query: 225 QKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAM 284
LEA + + L+ E LR+ ++G Q+ P E K+ +
Sbjct: 74 M---LEALVNEGSLALEELKMERDHLRKEVEGLRRQS-------PPASGEVNLGPNKMVV 123
Query: 285 DLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKS 325
DL DPNRPRFTLQELRDVL ERN+LKS++ ++QEEL YKS
Sbjct: 124 DLTDPNRPRFTLQELRDVLQERNKLKSQLLVVQEELQCYKS 164
Score = 56.2 bits (134), Expect = 5e-08
Identities = 37/89 (41%), Positives = 52/89 (58%), Gaps = 5/89 (5%)
Query: 2 EEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVL 61
E+E + E AL K+ +LT DVYDI+ L+G E + + +L KVVRVL
Sbjct: 16 EDEERDEVGPEGALGKSPFQLTAEDVYDISYLLGRELMALGSD---PRVTQLQFKVVRVL 72
Query: 62 EILEVLVSRHHVAPELDELRLELDRLRLE 90
E+LE LV+ +A L+EL++E D LR E
Sbjct: 73 EMLEALVNEGSLA--LEELKMERDHLRKE 99
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 68.6 bits (166), Expect = 1e-11
Identities = 84/376 (22%), Positives = 170/376 (45%), Gaps = 57/376 (15%)
Query: 57 VVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEA 116
V + LE E L H E +E ++ LR+ ++ + QK+LE + D + +
Sbjct: 1469 VAKHLETEEELKVAHCCLKEQEET---INELRVNLSEKETEISTIQKQLEAINDKLQNKI 1525
Query: 117 QDL--------LSQIAQLQEENKQLMTNLSHKDVNFSE---------------EEFQKHE 153
Q++ + QI+++QE+ +L H+ S +E Q+
Sbjct: 1526 QEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEI 1585
Query: 154 GMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVT 213
+ +E++ MK+++E + +RD+++ +E+ K ++ + + Q ++ +N + + ++
Sbjct: 1586 QIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVN-ETQEKMC 1644
Query: 214 VVEAQGKALIEQKVELEADLQTKE-----------QEMGSL---RAELGKLRERLQGEHS 259
+E + QK+ LE +++T+ +EM S+ R +L + E L+ E
Sbjct: 1645 EIEHLKEQFETQKLNLE-NIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERD 1703
Query: 260 QNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHER-NELKSKVFLLQE 318
Q E ET E + + V M LK+ T+ +LR ++ E+ NE+ + +Q+
Sbjct: 1704 QLKENLRETITRDLEKQEELKIVHMHLKEHQE---TIDKLRGIVSEKTNEISN----MQK 1756
Query: 319 ELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFFSRDKKRLANTQR-----N 373
+L + ++ +I + IAH Q E+ I +L S +L+N Q+ N
Sbjct: 1757 DLEHSNDALKAQDLKIQEELRIAHMHLKEQQET-IDKLRGIVSEKTDKLSNMQKDLENSN 1815
Query: 374 VHIQESFGQW-ANTHR 388
+QE + AN H+
Sbjct: 1816 AKLQEKIQELKANEHQ 1831
Score = 58.2 bits (139), Expect = 1e-08
Identities = 56/248 (22%), Positives = 125/248 (50%), Gaps = 18/248 (7%)
Query: 76 ELDELRLELDRLRLERMDRIEKERKHQKEL-ELVEDVWRGEAQDLLSQIAQLQEENKQLM 134
+L ++ +L+ + ++I++ + ++ +L L +DV E Q +S++ QL+++ K
Sbjct: 1803 KLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDV--NETQKKVSEMEQLKKQIKDQS 1860
Query: 135 TNLSHKDVNFSEEEFQKHEGMSE-----RERQVMKKLKEVVDKQRDEIRAKDRELGLKNE 189
LS ++ + HE + E +ER +++++E + +RD+++ +E K
Sbjct: 1861 LTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQE--TKAR 1918
Query: 190 DVEALQQQQT-RLMKINH-----DLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSL 243
D+E Q+ +T R++ H LR +++ Q + + + + +LQ K QE+
Sbjct: 1919 DLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKK 1978
Query: 244 RAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMD-LKDPNRPRFTLQELRDV 302
+L +++E + H + E E + +++S + V MD + + +L+E+R V
Sbjct: 1979 ELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLS-MQSVRMDNFQLTKKLHESLEEIRIV 2037
Query: 303 LHERNELK 310
ER+EL+
Sbjct: 2038 AKERDELR 2045
Score = 52.4 bits (124), Expect = 7e-07
Identities = 63/292 (21%), Positives = 128/292 (43%), Gaps = 19/292 (6%)
Query: 56 KVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGE 115
K+ V E E + H+ + + +L L+ + E + + ++ +E+ V E
Sbjct: 1632 KMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTK----E 1687
Query: 116 AQDLLSQIAQLQEENKQLMTNLSH---KDVNFSEEEFQKHEGMSERERQVMKKLKEVVDK 172
DL S L+ E QL NL +D+ EE H + E + + + KL+ +V +
Sbjct: 1688 RDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQ-ETIDKLRGIVSE 1746
Query: 173 QRDEIRAKDRELGLKNEDVEALQQQQTRLMKINH-DLRHRVT-------VVEAQGKALIE 224
+ +EI ++L N+ ++A + ++I H L+ + +V + L
Sbjct: 1747 KTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSN 1806
Query: 225 QKVELE---ADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEK 281
+ +LE A LQ K QE+ + +L L++ + + E E + + ++S++ ++
Sbjct: 1807 MQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKL 1866
Query: 282 VAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENR 333
+L + L+E++ V+ ER+ L+ L+ E K E + R
Sbjct: 1867 EIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKAR 1918
Score = 51.6 bits (122), Expect = 1e-06
Identities = 64/286 (22%), Positives = 131/286 (45%), Gaps = 34/286 (11%)
Query: 61 LEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQK----------ELELVED 110
L+I + + H +DELR + + ++ + E+ H K E EL+ +
Sbjct: 1237 LKIAHIHLKEHQET--IDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPN 1294
Query: 111 VWR-GEAQDLLSQIAQLQEEN----KQLMTNLSHKDVNFSE--EEFQKHEGMSERERQVM 163
V E Q+ ++++ L E++ + + + + +E +E Q+ +ER +
Sbjct: 1295 VKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNL 1354
Query: 164 KKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVE---AQGK 220
K +KE ++ + D+++ RE K ++ ++ Q+Q + + +++ V+ +E +
Sbjct: 1355 KTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDS 1414
Query: 221 ALIEQKVE---LEADLQTKEQEMGSLRAE---LGKLRERLQGEHSQNGEEEPETEPVGEE 274
AL+ ++E L LQ EM S+ E L +L+E LQ E Q E E E
Sbjct: 1415 ALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLE 1474
Query: 275 SISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEEL 320
+ + + LK+ T+ ELR L E+ ++++ +Q++L
Sbjct: 1475 TEEELKVAHCCLKEQEE---TINELRVNLSEK---ETEISTIQKQL 1514
Score = 50.8 bits (120), Expect = 2e-06
Identities = 76/318 (23%), Positives = 140/318 (44%), Gaps = 66/318 (20%)
Query: 67 LVSRHHVAPELDELRLELDRLRLERMD-RIEKER-----KHQKELELVEDVWRGEAQDLL 120
L+++ ++ EL+ LR + D L L+ R EKE K + +L+ E + R +D
Sbjct: 490 LLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKD-- 547
Query: 121 SQIAQLQEENKQLMTNLSHKDV---NFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDE- 176
Q QL E L + H +V + E K E + E+E Q+ KKL+E +D Q+ E
Sbjct: 548 -QEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQI-KKLQEYIDSQKLEN 605
Query: 177 -----------------------------IRAKDRELGLKNEDVEALQQQQTRLMKINHD 207
+ AK L++E++E L+++ L
Sbjct: 606 IKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLE-LKEKMKELATTYKQ 664
Query: 208 LRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAEL-GKLRE------RLQGE--- 257
+ + + + ++Q +A + +V+LE +LQ+ E+ L + + GK+ + L+G+
Sbjct: 665 MENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITD 724
Query: 258 -HSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLL 316
+ +E E E + EE I +E ++ + R R +Q+ + LH K K+F
Sbjct: 725 LQKELNKEVEENEALREEVILLSELKSLP-SEVERLRKEIQDKSEELHIITSEKDKLF-- 781
Query: 317 QEELAYYKSEEMEEENRI 334
SE + +E+R+
Sbjct: 782 --------SEVVHKESRV 791
Score = 48.5 bits (114), Expect = 1e-05
Identities = 61/265 (23%), Positives = 117/265 (44%), Gaps = 28/265 (10%)
Query: 66 VLVSRHHVAPELDELRLELDRLRLERMDRIEK----ERKHQKELELVEDVWRGEAQDLLS 121
V ++H + EL DRL EK + K Q+ L + E++ E Q ++
Sbjct: 1101 VAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEM--SEMQKKIN 1158
Query: 122 QIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSE-----RERQVMKKLKEVVDKQRDE 176
+I L+ E K L H + E + +E E +ER+V+K+L++ + +RD
Sbjct: 1159 EIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDH 1218
Query: 177 IRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTK 236
+R RE+ + LQ ++ + H H+ T+ E + + +K + Q
Sbjct: 1219 LRGYIREI-----EATGLQTKEELKIAHIHLKEHQETIDEL--RRSVSEKTAQIINTQDL 1271
Query: 237 EQEMGSLRAELGKLRERLQ-----GEHSQNGEEEPETEPVGEESI----SDAEKVAMD-L 286
E+ L+ E+ L E + E S+ E E E + E+S + ++ M+ L
Sbjct: 1272 EKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERL 1331
Query: 287 KDPNRPRFTLQELRDVLHERNELKS 311
+ + + + +E++ + ER+ LK+
Sbjct: 1332 RLNEKFQESQEEIKSLTKERDNLKT 1356
Score = 48.1 bits (113), Expect = 1e-05
Identities = 68/297 (22%), Positives = 129/297 (43%), Gaps = 35/297 (11%)
Query: 102 QKEL--ELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERE 159
QKEL E+ E+ E LLS++ L E ++L K++ EE H SE++
Sbjct: 726 QKELNKEVEENEALREEVILLSELKSLPSEVERL-----RKEIQDKSEEL--HIITSEKD 778
Query: 160 RQVMKKLKEVVDKQR------DEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVT 213
K EVV K+ +EI +L + ++ Q+ ++ D +
Sbjct: 779 ----KLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYK 834
Query: 214 VVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGE 273
+V + + + ++ V L + Q + +G+L+ EL + LQ + + E E E + E
Sbjct: 835 MVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKE 894
Query: 274 E------SISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEE 327
+ ++ E+ + + + + TL+E++ + E+++LK LQ E KS+
Sbjct: 895 QLENRDSTLQTVEREKTLITE--KLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDI 952
Query: 328 MEEEN-RIPQPPPIAHPRTS-PQPESGIKRLFSFFSRDKKRLANTQRNVHIQESFGQ 382
+ N I + + S Q + I L S S + RN+H++E+ G+
Sbjct: 953 HDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEE------VSRNLHMEENTGE 1003
Score = 40.8 bits (94), Expect = 0.002
Identities = 53/246 (21%), Positives = 106/246 (43%), Gaps = 27/246 (10%)
Query: 82 LELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKD 141
L +D + +M E ER +Q+ + L + EAQ S + L+ T LS+K
Sbjct: 825 LHMDFEQKYKMVLEENERMNQEIVNLSK-----EAQKFDSSLGALK-------TELSYKT 872
Query: 142 VNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKN-------EDVEAL 194
E+ + E ++E M++LKE ++ + ++ +RE L E+V+ L
Sbjct: 873 QELQEKTREVQERLNE-----MEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTL 927
Query: 195 QQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERL 254
Q++ L ++ L+ +++ + ++ + L+ + + + + L+ ++
Sbjct: 928 TQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKI 987
Query: 255 QGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVL-HERNELKSKV 313
E S+N E T +E + V +D K + T DV +E E + K+
Sbjct: 988 SEEVSRNLHMEENTGETKDE--FQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKI 1045
Query: 314 FLLQEE 319
F L +E
Sbjct: 1046 FSLIQE 1051
Score = 37.4 bits (85), Expect = 0.024
Identities = 43/205 (20%), Positives = 99/205 (48%), Gaps = 28/205 (13%)
Query: 76 ELDELRLELDRLRLERMDRIEKERKHQKELELV---EDVWRGEAQDLLSQIAQLQEENKQ 132
++ +++ +LD+ + E +I++ +K KEL+L+ EDV + ++++ QL+++ +
Sbjct: 1953 QISDIQKDLDKSKDELQKKIQELQK--KELQLLRVKEDV--NMSHKKINEMEQLKKQFEA 2008
Query: 133 LMTNLSHKDVNFSEEEFQK--HEGMSE-----RERQVMKKLKEVVDKQRDEIRAKDRELG 185
NLS + V + K HE + E +ER ++++KE + +RD+ A RE+
Sbjct: 2009 --QNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMI 2066
Query: 186 LKNEDVEALQQQQTRL----MKINHDLRHRVTVVEAQGKALIE--------QKVELEADL 233
++ ++ ++ L + LR + + ++ K E ++ L+ +
Sbjct: 2067 ARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEK 2126
Query: 234 QTKEQEMGSLRAELGKLRERLQGEH 258
+ + Q+ S+R + LQ +H
Sbjct: 2127 EIEFQKELSMRVKANLSLPYLQTKH 2151
Score = 32.0 bits (71), Expect = 1.0
Identities = 51/264 (19%), Positives = 116/264 (43%), Gaps = 34/264 (12%)
Query: 73 VAPELDELRLELDRLRLER-------MDRIEKERKHQK---ELELVEDVWRGEAQDLLSQ 122
VA E DELR + L++ER + I ++R++ + E L+ D Q L
Sbjct: 2037 VAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSD----GQQHLTES 2092
Query: 123 IAQLQEENKQLMTNLSHKDVNF-----------SEEEFQKHEGMSERERQVMKKLK-EVV 170
+ + K+L+ S D ++ E EFQK M + + L+ + +
Sbjct: 2093 LREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHI 2152
Query: 171 DKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHR-----VTVVEAQGKALIE- 224
+K + E + ++ + T++ + H+ ++ + VE Q + LI+
Sbjct: 2153 EKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKI 2212
Query: 225 QKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAM 284
Q ++ + D+ ++E L + E + + S++ E P + ++ +S+ +++
Sbjct: 2213 QHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSES--EFPSIKTEFQQVLSNRKEMTQ 2270
Query: 285 DLKDPNRPRFTLQELRDVLHERNE 308
L++ RF +++L++ + + N+
Sbjct: 2271 FLEEWLNTRFDIEKLKNGIQKEND 2294
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 65.9 bits (159), Expect = 6e-11
Identities = 82/345 (23%), Positives = 149/345 (43%), Gaps = 48/345 (13%)
Query: 12 ESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILEVLVSRH 71
++A E+ V++LT + A + E+ A+ KVV ++ E++
Sbjct: 1123 DAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVREIVRPDP 1182
Query: 72 HVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENK 131
E+ LRLEL +E+ERK++ E Q+ Q E +
Sbjct: 1183 KAESEVANLRLEL----------VEQERKYRGAEE---------------QLRSYQSELE 1217
Query: 132 QLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDV 191
L +V +E K++ E E+++ + +E+VDK R I D E+ +++
Sbjct: 1218 ALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTR-LIERCDLEIYQLKKEI 1276
Query: 192 EALQ----QQQTR-----LMKINHDLRHRVTVVEAQGKALIEQK--VELEADLQTKEQEM 240
+AL+ Q QT+ +++ D + + V + K EQK V+LE + ++E+++
Sbjct: 1277 QALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQI 1336
Query: 241 GSLRAELGKLRERLQGEHSQNGEEEP----ETEPVGEE---SISDAEKVAMDLKDPNRPR 293
EL +++ER+ + EEEP E E + +K+ +L+ R R
Sbjct: 1337 ARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRR 1396
Query: 294 F----TLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRI 334
L+EL R E + +V LQ+ LA + EE E ++
Sbjct: 1397 TELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKV 1441
Score = 45.1 bits (105), Expect = 1e-04
Identities = 67/296 (22%), Positives = 119/296 (40%), Gaps = 44/296 (14%)
Query: 79 ELRLELDRLRLERMDRIEKERKHQKE-------------------LELVED-VWRGEAQD 118
++R ELD ER ++E E K +E L+ V D V Q
Sbjct: 894 KIRKELDE-ETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQ 952
Query: 119 LLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLK------EVVDK 172
L +A+ Q +N+ L L + E + +G E + + +++ + V +
Sbjct: 953 LQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQ 1012
Query: 173 QRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVT---VVEAQGKALIEQKV-E 228
R+E+ A R+ G + +V LQQ+ L + + +VT VV+ Q +E + +
Sbjct: 1013 LREELEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQ 1072
Query: 229 LEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKD 288
L+ D Q ++Q EL L+++L+ + E G+ ++ + KV D
Sbjct: 1073 LQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAE------GKITVKEVLKVEKDAAT 1126
Query: 289 PNRPRFTLQELRDVL-------HERNELKSKVFLLQEELAYYKSEEMEEENRIPQP 337
++ D E+ EL K++ L+EE A +E E P P
Sbjct: 1127 EREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVREIVRPDP 1182
Score = 43.1 bits (100), Expect = 4e-04
Identities = 65/324 (20%), Positives = 142/324 (43%), Gaps = 30/324 (9%)
Query: 65 EVLVSRHHVAPELDELR------LELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQD 118
EVL+ + VA +E E + ++L+ ++E E + +E +D R + ++
Sbjct: 1030 EVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEE 1089
Query: 119 LLS----QIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQR 174
LS ++ +L++E ++ K+V E++ +S+ RQ + + QR
Sbjct: 1090 ELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQR 1149
Query: 175 DEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQ 234
++ + L+ E+ + + Q++ R ++ E++ L + VE E +
Sbjct: 1150 EKTELLRKIWALEEENAKVVVQEKVR------EIVRPDPKAESEVANLRLELVEQERKYR 1203
Query: 235 TKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRF 294
E+++ S ++EL LR R Q +E E + ++ + EK L++ +
Sbjct: 1204 GAEEQLRSYQSELEALRRR----GPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKT 1259
Query: 295 TLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIK 354
L E D+ E +LK ++ L++ +++E+ +E I + PQ + +
Sbjct: 1260 RLIERCDL--EIYQLKKEIQALKDTKPQVQTKEVVQE--------ILQFQEDPQTKEEVA 1309
Query: 355 RLFSFFSRDKKRLANTQRNVHIQE 378
L + S ++K+ + +R QE
Sbjct: 1310 SLRAKLSEEQKKQVDLERERASQE 1333
Score = 38.9 bits (89), Expect = 0.008
Identities = 89/405 (21%), Positives = 159/405 (39%), Gaps = 92/405 (22%)
Query: 1 MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRV 60
++E+ + + E VA L + V G E + Q EA+ R P+V
Sbjct: 1170 VQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQV--- 1226
Query: 61 LEILEVL--VSRHHVAPELDELRLELDRLRLERMDRIEK-ER------KHQKELELVEDV 111
E+ EV V ++ PE+++ EL RLR E +D+ ER + +KE++ ++D
Sbjct: 1227 -EVKEVTKEVIKYKTDPEMEK---ELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDT 1282
Query: 112 W-RGEAQDLLSQIAQLQEENK------QLMTNLSH---KDVNFSEEEFQKHEGMSERERQ 161
+ + ++++ +I Q QE+ + L LS K V+ E + E ++ +E +
Sbjct: 1283 KPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEE 1342
Query: 162 VMKKLKEVVD---------------------------KQRDEIRAKDRELGLKN------ 188
+ + + VV +Q D++RA+ R L +
Sbjct: 1343 LSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQ 1402
Query: 189 ---------------EDVEALQQQQTRLMKINHDLRHRVT----VVEAQGKALIEQKVEL 229
+V+ LQQ+ L + + R +VT VV Q + L
Sbjct: 1403 LEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALL 1462
Query: 230 EADLQTKEQEMGSLRAELGKLRERLQG-EHSQNGEEEPETEPVGEESISDAEKVAMDLKD 288
L+ ++ L EL LR +L E ++ E+ +E V E D E+ LK
Sbjct: 1463 RLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEK-GDTEQEIQRLK- 1520
Query: 289 PNRPRFTLQELRDVLHERNELKSKVFLLQ---EELAYYKSEEMEE 330
L + + EL +V L+ EL ++ S+ +E
Sbjct: 1521 --------SSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKE 1557
Score = 34.7 bits (78), Expect = 0.16
Identities = 42/186 (22%), Positives = 77/186 (41%), Gaps = 26/186 (13%)
Query: 79 ELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLS 138
EL +E+ RL + K KEL+ + R E L QL+ +N QL T
Sbjct: 1532 ELDVEVSRLEARLSELEFHNSKSSKELDFL----REENHKL-----QLERQNLQLETRRL 1582
Query: 139 HKDVNFSEEEFQKHEGMS---------------ERERQVMKKLKEVVDKQRDEIRAKDRE 183
++N + E + M+ ERE +K+L + D + DE++ +
Sbjct: 1583 QSEINMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLGS 1642
Query: 184 LGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSL 243
+ +K E E + ++ I+ D ++ EA LI+ + ++ Q + E S+
Sbjct: 1643 VAVKREQRE--NHLRRSIVVIHPDTGRELSPEEAHRAGLIDWNMFVKLRSQECDWEEISV 1700
Query: 244 RAELGK 249
+ G+
Sbjct: 1701 KGPNGE 1706
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 65.5 bits (158), Expect = 8e-11
Identities = 83/339 (24%), Positives = 151/339 (44%), Gaps = 53/339 (15%)
Query: 2 EEERGSALAAESA-LEKNVAELT--------------VMDVYDIASLVGHEFERVI-DQH 45
EEER L AE +++N+ EL + V A L E E++I +
Sbjct: 927 EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQ 986
Query: 46 GCEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKEL 105
C+ R+ E L + L +L+ + + + + +R+ +E K ++EL
Sbjct: 987 NCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL 1046
Query: 106 ELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQ----KHEGMSERERQ 161
E G++ DL QIA+LQ + +L L+ K EEE Q + E + ++
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK-----EEELQAALARVEEEAAQKNM 1101
Query: 162 VMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKA 221
+KK++E ++ Q E++ ED+E+ + + + K DL G+
Sbjct: 1102 ALKKIRE-LESQISELQ----------EDLESERASRNKAEKQKRDL----------GEE 1140
Query: 222 LIEQKVELE--ADLQTKEQEMGSLR-AELGKLRERLQGEHSQNGEEEPETEPVGEESISD 278
L K ELE D +QE+ S R E+ L++ L+ E + E + + + ++
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTH---EAQIQEMRQKHSQA 1197
Query: 279 AEKVAMDLKDPNRPRFTLQELRDVL-HERNELKSKVFLL 316
E++A L+ R + L++ + L +ER EL ++V +L
Sbjct: 1198 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236
Score = 54.3 bits (129), Expect = 2e-07
Identities = 50/274 (18%), Positives = 118/274 (43%), Gaps = 17/274 (6%)
Query: 49 AIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELV 108
A A K + L + L EL+ L + + M + K ELE
Sbjct: 1467 AEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKS 1526
Query: 109 EDVWRGEAQDLLSQIAQLQEE-------NKQLMTNLSHKDVNFSEEEFQKHEGMSERERQ 161
+ + +++ +Q+ +L++E +L NL F + + E E+++Q
Sbjct: 1527 KRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQ 1586
Query: 162 VMKKLKEVVDKQRDEIRAKDRELGLKNE---DVEALQQQQTRLMKINHDLRHRVTVVEAQ 218
++++++E+ + DE + + + + + D++ L+ K + ++ ++AQ
Sbjct: 1587 LVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQ 1646
Query: 219 GKALIEQ-------KVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPV 271
K + + + E+ A + E+++ S+ AE+ +L+E L + + E + +
Sbjct: 1647 MKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDEL 1706
Query: 272 GEESISDAEKVAMDLKDPNRPRFTLQELRDVLHE 305
+E + + K A+ L++ R + +L + L E
Sbjct: 1707 ADEIANSSGKGALALEEKRRLEARIAQLEEELEE 1740
Score = 52.8 bits (125), Expect = 6e-07
Identities = 74/320 (23%), Positives = 144/320 (45%), Gaps = 54/320 (16%)
Query: 44 QHGCEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQK 103
Q E +++ + V + LE +R + ELD+L ++LD R + +K++K +
Sbjct: 1391 QKDLEGLSQRHEEKVAAYDKLEKTKTR--LQQELDDLLVDLDHQRQSACNLEKKQKKFDQ 1448
Query: 104 EL--------ELVEDVWRGEA----------------QDLLSQIAQLQEENKQLMTNL-- 137
L + E+ R EA ++ + Q A+L+ NKQ T +
Sbjct: 1449 LLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMED 1508
Query: 138 ---SHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRA-KDRELGLKNEDVEA 193
S DV S E +K + E Q ++++K +++ DE++A +D +L L+ +++A
Sbjct: 1509 LMSSKDDVGKSVHELEKSKRALE---QQVEEMKTQLEELEDELQATEDAKLRLE-VNLQA 1564
Query: 194 LQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRER 253
++ Q R DL+ R E + K L+ Q E+EA+L+ + ++ A KL
Sbjct: 1565 MKAQFER------DLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMD 1618
Query: 254 LQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKV 313
L+ + +E+I K+ +KD ++EL D R E+ ++
Sbjct: 1619 LKDLEAHIDSANKNR----DEAIKQLRKLQAQMKD------CMRELDDTRASREEILAQA 1668
Query: 314 FLLQEELAYYKSE--EMEEE 331
+++L ++E +++EE
Sbjct: 1669 KENEKKLKSMEAEMIQLQEE 1688
Score = 49.7 bits (117), Expect = 5e-06
Identities = 45/190 (23%), Positives = 94/190 (49%), Gaps = 31/190 (16%)
Query: 161 QVMKKLKEVVDKQRDEIRAKDRELGLKNE--DVEALQQQ--------------QTRLMKI 204
QV ++ +E++ K+ + ++ ++++L +N ++E LQ Q +T L
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 205 NHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEE 264
+LR R+T A+ + L E +LEA ++ +E+ L+AE K+++ +Q Q EE
Sbjct: 899 AEELRARLT---AKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEE 955
Query: 265 EPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERN-ELKSKVFLLQEELAYY 323
E + + E ++ K+ L+E + +L ++N +L + LL++ +A +
Sbjct: 956 ESARQKLQLEKVTTEAKLK-----------KLEEEQIILEDQNCKLAKEKKLLEDRIAEF 1004
Query: 324 KSEEMEEENR 333
+ EEE +
Sbjct: 1005 TTNLTEEEEK 1014
Score = 47.4 bits (111), Expect = 2e-05
Identities = 61/320 (19%), Positives = 133/320 (41%), Gaps = 50/320 (15%)
Query: 61 LEILEVLVSRHHVAPELDELRLELDRLRLERMD-------RIEKERKHQKELELVEDVWR 113
L++ E L + + E +ELR L + E + R+E+E + + L+ + +
Sbjct: 883 LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 114 GEAQDLLSQIAQLQEENKQLMTN-----------------LSHKDVNFSEEEFQKHEGMS 156
Q+L Q+ + + ++L L ++ ++E+ + ++
Sbjct: 943 QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 157 E------RERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRH 210
E E + K L ++ +K I + L + + + L++ + +L + DL
Sbjct: 1003 EFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSD 1062
Query: 211 RVTVVEAQ----GKALIEQKVELEADLQTKEQE----------MGSLRAELGKLRERLQG 256
++ ++AQ L +++ EL+A L E+E + L +++ +L+E L+
Sbjct: 1063 QIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLES 1122
Query: 257 EHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLL 316
E + + E + +GEE E + +L+D QELR + + K L
Sbjct: 1123 ERASRNKAEKQKRDLGEE----LEALKTELEDTLDSTAAQQELRSKREQEVNILKKT--L 1176
Query: 317 QEELAYYKSEEMEEENRIPQ 336
+EE ++++ E + Q
Sbjct: 1177 EEEAKTHEAQIQEMRQKHSQ 1196
Score = 45.8 bits (107), Expect = 7e-05
Identities = 73/377 (19%), Positives = 152/377 (40%), Gaps = 56/377 (14%)
Query: 3 EERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLE 62
EER A A A EK L++ + A E ER+ Q E + K
Sbjct: 1462 EERDRAEA--EAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519
Query: 63 ILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQ-DLLS 121
+ E+ S+ + +++E++ +L+ L D ++ + LE+ + + + DL
Sbjct: 1520 VHELEKSKRALEQQVEEMKTQLEELE----DELQATEDAKLRLEVNLQAMKAQFERDLQG 1575
Query: 122 QIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVM--KKLKEVVD---KQRDE 176
+ Q +E+ KQL+ + + +E Q+ ++ R++ M K L+ +D K RDE
Sbjct: 1576 RDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDE 1635
Query: 177 I------------------------------RAKDRELGLKNEDVEALQQQQT------- 199
+AK+ E LK+ + E +Q Q+
Sbjct: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 1695
Query: 200 --RLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGE 257
+ + +L + +G +E+K LEA + E+E+ + + +RL+
Sbjct: 1696 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
Query: 258 HSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRP-RFTLQELRDVLHERNELKSKVFLL 316
+ Q + + + E L+ N+ + LQE+ + +++ K+ + L
Sbjct: 1756 NLQIDQINTDLN-LERSHAQKNENARQQLERQNKELKVKLQEMEGTV--KSKYKASITAL 1812
Query: 317 QEELAYYKSEEMEEENR 333
+ ++A + E+++ E +
Sbjct: 1813 EAKIAQLE-EQLDNETK 1828
Score = 33.5 bits (75), Expect = 0.35
Identities = 56/261 (21%), Positives = 109/261 (41%), Gaps = 16/261 (6%)
Query: 1 MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFE----RVIDQHGCEAIARLMPK 56
+E+ S A + K E+ ++ HE + R E +A + +
Sbjct: 1148 LEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQ 1207
Query: 57 VVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKEL-ELVEDVWRGE 115
RV LE ++ + E EL E+ L + D K +K + +L EL GE
Sbjct: 1208 TKRVKANLEK--AKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGE 1265
Query: 116 A--QDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQ 173
+L ++ +LQ E + LS D S+ K E + Q ++L + ++Q
Sbjct: 1266 RVRTELADKVTKLQVELDNVTGLLSQSDSKSSK--LTKDFSALESQLQDTQELLQEENRQ 1323
Query: 174 RDEIRAKDREL-GLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEAD 232
+ + K +++ KN E L++++ + H+L ++ + AQ + ++ +
Sbjct: 1324 KLSLSTKLKQVEDEKNSFREQLEEEE----EAKHNLEKQIATLHAQVADMKKKMEDSVGC 1379
Query: 233 LQTKEQEMGSLRAELGKLRER 253
L+T E+ L+ +L L +R
Sbjct: 1380 LETAEEVKRKLQKDLEGLSQR 1400
Score = 32.7 bits (73), Expect = 0.60
Identities = 33/146 (22%), Positives = 66/146 (45%), Gaps = 6/146 (4%)
Query: 86 RLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEE--NKQLMTNLSHKDVN 143
R +LER ++ E + K Q+ V+ ++ L ++IAQL+E+ N+ + K V
Sbjct: 1780 RQQLERQNK-ELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVR 1838
Query: 144 FSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMK 203
+E++ + + ER+ ++ K+ DK ++ R+L E E Q+ K
Sbjct: 1839 RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQL---EEAEEEAQRANASRRK 1895
Query: 204 INHDLRHRVTVVEAQGKALIEQKVEL 229
+ +L +A + + K +L
Sbjct: 1896 LQRELEDATETADAMNREVSSLKNKL 1921
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 61.6 bits (148), Expect = 1e-09
Identities = 39/197 (19%), Positives = 102/197 (51%), Gaps = 21/197 (10%)
Query: 96 EKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGM 155
E+ +K +++++ E+ R + + + Q Q++E+ +Q+ L K+ EE+ + E
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM---LKQKEQTEQEEQTGEQEEQ 297
Query: 156 SERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDV----EALQQQQTRLMKINHDL--- 208
+ + M++ +E + +Q +++R ++ ++G + E + E + +Q+ ++ K +
Sbjct: 298 MREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQ 357
Query: 209 -------RHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQN 261
+V E Q + EQ + E ++ +E++MG + ++G+ +E+++ + Q
Sbjct: 358 EEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQM 417
Query: 262 GEEE----PETEPVGEE 274
GE++ + E +GE+
Sbjct: 418 GEQKEQMRKQEEHMGEQ 434
Score = 55.5 bits (132), Expect = 9e-08
Identities = 49/265 (18%), Positives = 119/265 (44%), Gaps = 17/265 (6%)
Query: 81 RLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHK 140
+LE D++ L + ++ ++ +E E G+ ++ Q+ + + + ++ + +
Sbjct: 40 KLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 99
Query: 141 DVNFSEEEFQ--KHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQ 198
+ E+E Q + EG + +++ + V +Q ++R ++ G E +++Q+
Sbjct: 100 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE---GQVREQEGQVREQE 156
Query: 199 TRLMKINHDLRHRVTVVEAQGKALIEQKVEL---EADLQTKEQEMGSLRAELGKLRERLQ 255
++ + +R + V Q + EQ+ ++ E + +E +MG ++G+ E++Q
Sbjct: 157 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQ 216
Query: 256 GEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNE------- 308
+ Q GE+E + E+ E+V + + +++ + + E+ E
Sbjct: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEE 276
Query: 309 --LKSKVFLLQEELAYYKSEEMEEE 331
LK K QEE + E+M E+
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQ 301
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/230 (18%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query: 115 EAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQR 174
+ + + Q Q+ E+ +Q+ + + EE+ QK E +++ + M+K +E + +Q
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQ--EEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQE 268
Query: 175 DEIRAKDRELGLKNEDVEALQQ---QQTRLMKINHDLRHRVTVVEAQGKALIEQKVEL-- 229
+++R ++ ++ + E E +Q Q+ ++ + +R + + Q + + EQ+ ++
Sbjct: 269 EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328
Query: 230 --EADLQTKEQ------EMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEK 281
E + KEQ +M ++G+ E++Q + Q ++E + E+ E+
Sbjct: 329 QEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388
Query: 282 VAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEE 331
+ + + + E ++ + E+ E + Q+E + E M E+
Sbjct: 389 MRKQEEQMGEQKEQMGEQKEQMREQEEQMGE----QKEQMRKQEEHMGEQ 434
Score = 45.8 bits (107), Expect = 7e-05
Identities = 56/266 (21%), Positives = 122/266 (45%), Gaps = 23/266 (8%)
Query: 76 ELDELRLEL-DRLRLERMDRIE-----KERKHQKELELVEDVWRGEAQDLLSQIAQLQEE 129
EL E EL + L+L ++ E KE K + E + + G+ ++ Q Q++E+
Sbjct: 8 ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVRE---QEGQVREQ 64
Query: 130 NKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNE 189
Q+ V E + ++ EG + +++ + V +Q ++R ++ G E
Sbjct: 65 EGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE---GQVRE 119
Query: 190 DVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVEL-EADLQTKEQEMGSLRAELG 248
+++Q+ ++ + +R + V Q + EQ+ ++ E + Q +EQE G +R + G
Sbjct: 120 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQEG 178
Query: 249 KLRE---RLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHE 305
++RE +++ + Q GE+E + E+ E++ + +++ + + E
Sbjct: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238
Query: 306 RNELKSKVFLLQEELAYYKSEEMEEE 331
+ E K QEE + E+M ++
Sbjct: 239 QEEQVQK----QEEQVQKQEEQMRKQ 260
Score = 40.0 bits (92), Expect = 0.004
Identities = 30/139 (21%), Positives = 72/139 (51%), Gaps = 14/139 (10%)
Query: 96 EKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEF--QKHE 153
E+ R+ ++++ E+ R + + + Q Q+ E+ +Q+ K+ + +EE ++ E
Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMW---EQKEQMWKQEEQMGEQEE 359
Query: 154 GMSERERQV------MKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHD 207
M ++E QV M+K +E + KQ +++R ++ ++G E E + +Q+ ++ +
Sbjct: 360 QMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMG---EQKEQMGEQKEQMREQEEQ 416
Query: 208 LRHRVTVVEAQGKALIEQK 226
+ + + Q + + EQK
Sbjct: 417 MGEQKEQMRKQEEHMGEQK 435
Score = 39.3 bits (90), Expect = 0.006
Identities = 45/244 (18%), Positives = 105/244 (43%), Gaps = 23/244 (9%)
Query: 92 MDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEE-EFQ 150
M RI E +K EL E E Q + ++ +++Q K+L L + +E + +
Sbjct: 1 MPRITNEELKEKNAELQE-----ELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVR 55
Query: 151 KHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRH 210
+ EG + +++ + V +Q ++R ++ ++ + V + Q
Sbjct: 56 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ------------- 102
Query: 211 RVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEP 270
V E +G+ ++ E + Q +EQE G +R + G++RE+ Q G+ +
Sbjct: 103 ---VREQEGQVREQEGQVREQEGQVREQE-GQVREQEGQVREQEGQVREQEGQVREQEGQ 158
Query: 271 VGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEE 330
V E+ E+ + + R ++R+ + E + ++ +E++ + + ++
Sbjct: 159 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ 218
Query: 331 ENRI 334
E ++
Sbjct: 219 EEQM 222
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 61.2 bits (147), Expect = 2e-09
Identities = 78/313 (24%), Positives = 140/313 (44%), Gaps = 28/313 (8%)
Query: 69 SRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQE 128
S+ VA E DE+ + R + E +E+ RK ++E E R E Q + A E
Sbjct: 434 SKQQVADE-DEIWKQRRRQQSEISAAVERARKRREEEER-----RMEEQ----RKAACAE 483
Query: 129 ENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGL-K 187
+ K+L L + S EE ++ E ERER+ K+L++ +++R++ R KDRE K
Sbjct: 484 KLKRLDEKLGILEKQPSPEEIREREREKERERE--KELEKEQEQEREKEREKDRERQQEK 541
Query: 188 NEDVEALQQQQTRLMKINHD------LRHRVTVVEAQGKALIEQKVELEADLQTKEQEMG 241
+++E Q++Q + K R + E Q E++ ELE + + E+++
Sbjct: 542 EKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIE 601
Query: 242 SLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRD 301
L + E+ + E+S N EEEP + + +EK A + P Q
Sbjct: 602 PREPNLEPMVEKQESENSCNKEEEP---VFTRQDSNRSEKEATPVVHETEPESGSQPRPA 658
Query: 302 VL-----HERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRL 356
VL + L + QE++ + ++ +++ +PQ P + P +S P + L
Sbjct: 659 VLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVP-SQPSSSTVPPPPHRPL 717
Query: 357 FSFFSRDKKRLAN 369
+ + LA+
Sbjct: 718 YQPMQPHPQHLAS 730
Score = 33.9 bits (76), Expect = 0.27
Identities = 64/275 (23%), Positives = 102/275 (37%), Gaps = 49/275 (17%)
Query: 103 KELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQV 162
K E EDV A D A E+ QL +H +F E E QV
Sbjct: 824 KATEEPEDVRSEAALDQEQITAAYSVEHNQLE---AHPKADFIRES---------SEAQV 871
Query: 163 MKKLKEVVDKQRDE----------IRAKDREL--GLKNEDVEALQQQQTRLMKINHDLRH 210
K L V+ R A D++ + E + A++ Q +R ++H H
Sbjct: 872 QKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNH 931
Query: 211 RVTVVEAQGKA----------LIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQ 260
E + + I+ K +E + K ++ G +R+ G E++ S+
Sbjct: 932 TQKPDEQRSEPSAGIPKVTSRCIDSKEPIERP-EEKPKKEGFIRSSEGPKPEKVYKSKSE 990
Query: 261 NGEEEPETEPVGEESISDAE-KVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQE- 318
P E ++D + + +K P LRD+ ER + K K E
Sbjct: 991 T-RWGPRPSSNRREEVNDRPVRRSGPIKKP--------VLRDMKEEREQRKEKEGEKAEK 1041
Query: 319 --ELAYYKSEEMEEENRIPQPPPIAHPRTSPQPES 351
E K E+ E+++ +P PPP P QP+S
Sbjct: 1042 VTEKVVVKPEKTEKKD-LPPPPPPPQPPAPIQPQS 1075
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 60.1 bits (144), Expect = 3e-09
Identities = 56/284 (19%), Positives = 134/284 (47%), Gaps = 18/284 (6%)
Query: 65 EVLVSRHHVAPELDELRLELDRLRLERMDRIEKE--RKHQKELELVEDVWRGEAQDLLSQ 122
E++ + EL+E E +++R + R E+E R+ +K E +WR E + + Q
Sbjct: 384 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE-EKIREQ 442
Query: 123 IAQLQEENKQLMTNLS--HKDVNFSEEEF-QKHEGMSERERQVMK-----KLKEVVDKQR 174
+++E+ K++ H+ EEE Q+ E M +E ++ + + KE + +Q
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE 502
Query: 175 DEIRAKDRELGLKNEDV----EALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELE 230
++IR ++ ++ + E + E +++Q+ ++ + +R + + + K ++K+ E
Sbjct: 503 EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEE 562
Query: 231 ADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPN 290
Q +E +M ++ + E++ + + E+E + + E+ EK+ +
Sbjct: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQ 622
Query: 291 RPRFTLQELRDVLHERNEL---KSKVFLLQEELAYYKSEEMEEE 331
++E + + E+ E+ + + QEE + E+M+E+
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666
Score = 58.2 bits (139), Expect = 1e-08
Identities = 55/253 (21%), Positives = 129/253 (50%), Gaps = 34/253 (13%)
Query: 96 EKERKHQKELEL---VEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKH 152
+KE+ H++E ++ E VWR E + + Q +++E+ +++ + + EE +++
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQE-EKIREQEEKIREQEEKMWRQ--EEKIREQEEMWREE 550
Query: 153 EGMSERER-QVMKKLKEVVDK---QRDEIRAKDRELGLKNEDV----EALQQQQTRLMKI 204
E M E+E+ +K +E DK Q ++IR ++ ++ + E + E Q+Q+ ++ K
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 205 NHDLRHRVTVVEAQGKALIEQKVEL---EADLQTKEQEMGSLRAELGKLRERLQGEHSQN 261
+R + ++ Q + + EQ+ ++ E Q +E++MG ++ + E++Q
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ------ 664
Query: 262 GEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELA 321
E+ ET EE I + EK + ++ ++E +++ E+ E K++ +E++
Sbjct: 665 --EQEETMWRQEEKIREQEKKIREQEE------KIREQEEMMQEQEE---KMWEQEEKMC 713
Query: 322 YYKSEEMEEENRI 334
+ + E+E ++
Sbjct: 714 EQEEKMQEQEEKM 726
Score = 52.0 bits (123), Expect = 1e-06
Identities = 67/283 (23%), Positives = 121/283 (42%), Gaps = 30/283 (10%)
Query: 76 ELDELRLELDRLRLERMDRIEKERKHQKELELVED------------VWRGEAQDLLSQI 123
E D L LEL R + + EK K Q++L+LVE + E LL
Sbjct: 201 ERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ 260
Query: 124 AQLQEE----NKQLMTNLSHKDVNFSEEEF-----QKHEGMSERERQVMKKLKEVVDKQR 174
QLQ E K+L + + E E Q+ E R+ + +++ +E + +Q
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Query: 175 DEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVV-EAQGKALIEQKVELEADL 233
++IR ++ ++ E E +++Q+ + + +R + ++ E + K ++++ E +
Sbjct: 321 EKIREQEEKI---REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 377
Query: 234 QTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPR 293
+ + QE E K+RE + H Q E E + EE I + EK R
Sbjct: 378 KMRRQEEMMWEKE-EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 294 FTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQ 336
++E + + E + K QEE + + + EEE R Q
Sbjct: 437 EKIREQEEKIRE----QEKKMWRQEEKIHEQEKIREEEKRQEQ 475
Score = 45.8 bits (107), Expect = 7e-05
Identities = 34/178 (19%), Positives = 89/178 (50%), Gaps = 12/178 (6%)
Query: 88 RLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEE 147
R E+ D++ ++ + +E E E VWR E + + Q + QE+ +++ + + EE
Sbjct: 565 RQEQEDKMWRQEEKIREQE--EKVWRQE-EKIREQEEKRQEQEEKMWKQ--EEKIREQEE 619
Query: 148 EFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHD 207
+ Q+ E + + +++ +E+ +Q +++ ++ ++ E E +Q+Q+ + +
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC---EQEEKMQEQEETMWRQEEK 676
Query: 208 LRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEE 265
+R + + Q + + EQ E +Q +E++M ++ + E++Q + + +E
Sbjct: 677 IREQEKKIREQEEKIREQ----EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Score = 45.1 bits (105), Expect = 1e-04
Identities = 44/263 (16%), Positives = 123/263 (46%), Gaps = 23/263 (8%)
Query: 78 DELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNL 137
++++ + +++R + E+E K +++ E++ W E ++ + + ++ E ++ M
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMM---W--EKEEKMRRQEEMMWEKEEKMRRQ 368
Query: 138 SHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNE----DVEA 193
E+ ++ E M E+E +K++E+ +K ++ + +++E + E + E
Sbjct: 369 EEMMWEKEEKMRRQEEMMWEKE----EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 424
Query: 194 LQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRER 253
Q+Q+ ++ + +R + + Q K + Q+ ++ + +E+E + E+ + E+
Sbjct: 425 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 484
Query: 254 LQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNE--LKS 311
+ E+ E E+ EK+ + R ++E + + E+ E +
Sbjct: 485 I--------HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQ 536
Query: 312 KVFLLQEELAYYKSEEMEEENRI 334
+ + ++E + + E+M E+ +I
Sbjct: 537 EEKIREQEEMWREEEKMHEQEKI 559
Score = 36.6 bits (83), Expect = 0.041
Identities = 34/178 (19%), Positives = 87/178 (48%), Gaps = 22/178 (12%)
Query: 88 RLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEE 147
R E R ++E++ ++E E +W+ E + + Q ++QE+ +++ EE
Sbjct: 588 RQEEKIREQEEKRQEQE----EKMWKQE-EKIREQEEKIQEQEEKIREQ---------EE 633
Query: 148 EFQKHEGMSERERQVM----KKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMK 203
+ ++ E M++ + + M +K+ E +K +++ R+ E + +++Q+ ++ +
Sbjct: 634 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE 693
Query: 204 INHDLRHRVTVVEAQGKALIEQK---VELEADLQTKEQEMGSLRAELGKLRERLQGEH 258
++ + + Q + + EQ+ E E ++ +E++M L + E++Q EH
Sbjct: 694 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ-EH 750
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 60.1 bits (144), Expect = 3e-09
Identities = 95/401 (23%), Positives = 163/401 (40%), Gaps = 74/401 (18%)
Query: 59 RVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQD 118
R+ E L++LRL+ + + DR+ KE K ++ELE ++ GE+ +
Sbjct: 1032 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1091
Query: 119 LLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERE----RQVMKKLKE----VV 170
L Q+ + Q+ ++L L K EEE Q +E E Q++K L+E +
Sbjct: 1092 LQEQMVEQQQRAEELRAQLGRK-----EEELQAALARAEDEGGARAQLLKSLREAQAALA 1146
Query: 171 DKQRD---------EIRAKDRELGLKNEDVEAL---------------------QQQQTR 200
+ Q D + + R+LG E++EAL +Q+ T
Sbjct: 1147 EAQEDLESERVARTKAEKQRRDLG---EELEALRGELEDTLDSTNAQQELRSKREQEVTE 1203
Query: 201 LMK-INHDLR-HRVTVVEAQ---GKALIEQKVELEADLQTK----------EQEMGSLRA 245
L K + + R H V E + G+AL E +LE + K E E+ LRA
Sbjct: 1204 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1263
Query: 246 ELGKLR-ERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLH 304
EL L+ R +GE + E E G D E+ + + + + EL +V
Sbjct: 1264 ELSSLQTARQEGEQRRRRLELQLQEVQGR--AGDGERARAEAAE--KLQRAQAELENVSG 1319
Query: 305 ERNELKSKVFLLQEELA-----YYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSF 359
NE +SK L +EL+ + ++E+ +E + + R +G++
Sbjct: 1320 ALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1379
Query: 360 FSRDKKRLANTQRNVHIQESFGQWANTHRDD-GYTEQGQEA 399
+ ++R + Q S +W ++ G E G+EA
Sbjct: 1380 EAAARERAGRELQTAQAQLS--EWRRRQEEEAGALEAGEEA 1418
Score = 50.1 bits (118), Expect = 4e-06
Identities = 84/334 (25%), Positives = 144/334 (43%), Gaps = 52/334 (15%)
Query: 2 EEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVL 61
EE RG A + LE V+EL VG E E +R M + L
Sbjct: 932 EETRGRLAARKQELELVVSELEAR--------VGEE----------EECSRQMQTEKKRL 973
Query: 62 EILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLS 121
+ + H A E +L+L+++ E K +K +++L L+ED
Sbjct: 974 QQHIQELEAHLEAEEGARQKLQLEKVTTEA-----KMKKFEEDLLLLED----------- 1017
Query: 122 QIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKD 181
Q ++L +E K L L+ +EEE +K + +++ + + ++ D+ R E + +
Sbjct: 1018 QNSKLSKERKLLEDRLAEFSSQAAEEE-EKVKSLNKLRLKYEATIADMEDRLRKEEKGRQ 1076
Query: 182 RELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMG 241
LK L + + L + + + R + AQ L ++ EL+A L E E G
Sbjct: 1077 ELEKLKRR----LDGESSELQEQMVEQQQRAEELRAQ---LGRKEEELQAALARAEDE-G 1128
Query: 242 SLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDL-KDPNRPRFTLQELR 300
RA+L K Q ++ +E+ E+E V + AEK DL ++ R L++
Sbjct: 1129 GARAQLLKSLREAQAALAE-AQEDLESERVAR---TKAEKQRRDLGEELEALRGELEDTL 1184
Query: 301 DVLHERNELKSKVFLLQEELAYYKSEEMEEENRI 334
D + + EL+SK +E+ + +EEE RI
Sbjct: 1185 DSTNAQQELRSK----REQEVTELKKTLEEETRI 1214
Score = 48.5 bits (114), Expect = 1e-05
Identities = 75/314 (23%), Positives = 129/314 (41%), Gaps = 25/314 (7%)
Query: 69 SRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQ-DLLSQIAQLQ 127
+R A E + L L + E +DR+E+ R+ ++ EL + E Q L+S + + Q
Sbjct: 1418 ARRRAAREAEALTQRLAE-KTETVDRLERGRRRLQQ-ELDDATMDLEQQRQLVSTLEKKQ 1475
Query: 128 EENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQ--RDEIRAKDRELG 185
+ QL+ + EE + ERE + + + + ++Q R+E+ ++R L
Sbjct: 1476 RKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL- 1534
Query: 186 LKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRA 245
++EAL + + K H+L V E L Q ELE +L E LR
Sbjct: 1535 --RAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAED--AKLRL 1590
Query: 246 ELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDL---KDPNRPRFTLQELRDV 302
E+ + Q E G +E GEE K D +D R + TL
Sbjct: 1591 EVTVQALKTQHERDLQGRDE-----AGEERRRQLAKQLRDAEVERDEERKQRTL-----A 1640
Query: 303 LHERNELKSKVFLLQEELAY--YKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFF 360
+ R +L+ ++ L+ ++A EE ++ R Q R + + + +FS
Sbjct: 1641 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1700
Query: 361 SRDKKRLANTQRNV 374
+KRL + V
Sbjct: 1701 RESEKRLKGLEAEV 1714
Score = 46.2 bits (108), Expect = 5e-05
Identities = 95/394 (24%), Positives = 151/394 (38%), Gaps = 73/394 (18%)
Query: 3 EERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVL- 61
++R A+AA LE + EL + G E + Q R M ++ L
Sbjct: 1635 KQRTLAVAARKKLEGELEELKAQ-----MASAGQGKEEAVKQ------LRKMQAQMKELW 1683
Query: 62 -EILEVLVSRHHVAPELDELR-----LELDRLRLER----MDRIEKERKHQKELELVEDV 111
E+ E SR + + E LE + LRL+ DR ++ + ++ E+ ++V
Sbjct: 1684 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRD-EMADEV 1742
Query: 112 WRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVD 171
G LS+ A L EE +QL L EEE ++ + SE +KL V+
Sbjct: 1743 ANGN----LSKAAIL-EEKRQLEGRLGQL-----EEELEEEQSNSELLNDRYRKLLLQVE 1792
Query: 172 KQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDL---------RHRVTVVEAQGK-A 221
E+ A +R K E QQ + ++ ++ L RH++T+ + K A
Sbjct: 1793 SLTTELSA-ERSFSAKAES--GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLA 1849
Query: 222 LIEQKVELEAD--------------------LQTKEQEM--GSLRAEL--GKLRERLQGE 257
E+++E E LQ +E+ LR +L G LR +
Sbjct: 1850 QAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKR 1909
Query: 258 HSQNGEEEPETEPVGEESIS-DAEKVAMDLKDPNRPRFTLQEL--RDVLHERNELKSKVF 314
+ EEE G + + E V + NR TL+ R L +VF
Sbjct: 1910 QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVF 1969
Query: 315 LLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQ 348
L+E +A + E + P P P P PQ
Sbjct: 1970 RLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2003
Score = 43.5 bits (101), Expect = 3e-04
Identities = 61/265 (23%), Positives = 118/265 (44%), Gaps = 34/265 (12%)
Query: 87 LRLERMDRIEKERKHQKELELVEDVWRGEAQD---LLSQIAQLQEENKQLMTNLSHKDVN 143
L++ R D + + R +EL+ V+++ + A++ L ++AQL+EE +L L +
Sbjct: 870 LQVTRQDEVLQARA--QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 927
Query: 144 FSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMK 203
+E +E R + K+ ++ E+ A+ +G + E +Q ++ RL +
Sbjct: 928 CAE---------AEETRGRLAARKQELELVVSELEAR---VGEEEECSRQMQTEKKRLQQ 975
Query: 204 INHDLRHRVTVVEAQGKALIEQKVELEA-------DLQTKEQEMGSLRAELGKLRERLQG 256
+L + E + L +KV EA DL E + L E L +RL
Sbjct: 976 HIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE 1035
Query: 257 EHSQNGEEEPETEPVG------EESISDAEKVAMDLKDPNRPRFTLQELRDVLH-ERNEL 309
SQ EEE + + + E +I+D E L+ + R L++L+ L E +EL
Sbjct: 1036 FSSQAAEEEEKVKSLNKLRLKYEATIADMED---RLRKEEKGRQELEKLKRRLDGESSEL 1092
Query: 310 KSKVFLLQEELAYYKSEEMEEENRI 334
+ ++ Q+ +++ +E +
Sbjct: 1093 QEQMVEQQQRAEELRAQLGRKEEEL 1117
Score = 32.0 bits (71), Expect = 1.0
Identities = 57/276 (20%), Positives = 105/276 (38%), Gaps = 11/276 (3%)
Query: 56 KVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGE 115
K +R+ + L ++ H A EL + R+ +E E +E +L E+ E
Sbjct: 1327 KTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLRE-QLEEEAAARE 1385
Query: 116 AQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRD 175
Q AQ Q + + EE ++ +E Q + + E VD+
Sbjct: 1386 RAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLER 1445
Query: 176 EIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQT 235
R +EL D+E +Q + L K + +A +E++ EA+ +
Sbjct: 1446 GRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRE 1505
Query: 236 KEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFT 295
+E SL L + +E + QN E E + +S + V + + R
Sbjct: 1506 REARALSLTRALEEEQEAREELERQNRALRAELEAL----LSSKDDVGKSVHELER---- 1557
Query: 296 LQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEE 331
R N+L+++V L++EL + ++ E
Sbjct: 1558 --ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLE 1591
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 60.1 bits (144), Expect = 3e-09
Identities = 95/401 (23%), Positives = 163/401 (40%), Gaps = 74/401 (18%)
Query: 59 RVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQD 118
R+ E L++LRL+ + + DR+ KE K ++ELE ++ GE+ +
Sbjct: 1024 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1083
Query: 119 LLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERE----RQVMKKLKE----VV 170
L Q+ + Q+ ++L L K EEE Q +E E Q++K L+E +
Sbjct: 1084 LQEQMVEQQQRAEELRAQLGRK-----EEELQAALARAEDEGGARAQLLKSLREAQAALA 1138
Query: 171 DKQRD---------EIRAKDRELGLKNEDVEAL---------------------QQQQTR 200
+ Q D + + R+LG E++EAL +Q+ T
Sbjct: 1139 EAQEDLESERVARTKAEKQRRDLG---EELEALRGELEDTLDSTNAQQELRSKREQEVTE 1195
Query: 201 LMK-INHDLR-HRVTVVEAQ---GKALIEQKVELEADLQTK----------EQEMGSLRA 245
L K + + R H V E + G+AL E +LE + K E E+ LRA
Sbjct: 1196 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1255
Query: 246 ELGKLR-ERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLH 304
EL L+ R +GE + E E G D E+ + + + + EL +V
Sbjct: 1256 ELSSLQTARQEGEQRRRRLELQLQEVQGR--AGDGERARAEAAE--KLQRAQAELENVSG 1311
Query: 305 ERNELKSKVFLLQEELA-----YYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSF 359
NE +SK L +EL+ + ++E+ +E + + R +G++
Sbjct: 1312 ALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1371
Query: 360 FSRDKKRLANTQRNVHIQESFGQWANTHRDD-GYTEQGQEA 399
+ ++R + Q S +W ++ G E G+EA
Sbjct: 1372 EAAARERAGRELQTAQAQLS--EWRRRQEEEAGALEAGEEA 1410
Score = 50.1 bits (118), Expect = 4e-06
Identities = 84/334 (25%), Positives = 144/334 (43%), Gaps = 52/334 (15%)
Query: 2 EEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVL 61
EE RG A + LE V+EL VG E E +R M + L
Sbjct: 924 EETRGRLAARKQELELVVSELEAR--------VGEE----------EECSRQMQTEKKRL 965
Query: 62 EILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLS 121
+ + H A E +L+L+++ E K +K +++L L+ED
Sbjct: 966 QQHIQELEAHLEAEEGARQKLQLEKVTTEA-----KMKKFEEDLLLLED----------- 1009
Query: 122 QIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKD 181
Q ++L +E K L L+ +EEE +K + +++ + + ++ D+ R E + +
Sbjct: 1010 QNSKLSKERKLLEDRLAEFSSQAAEEE-EKVKSLNKLRLKYEATIADMEDRLRKEEKGRQ 1068
Query: 182 RELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMG 241
LK L + + L + + + R + AQ L ++ EL+A L E E G
Sbjct: 1069 ELEKLKRR----LDGESSELQEQMVEQQQRAEELRAQ---LGRKEEELQAALARAEDE-G 1120
Query: 242 SLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDL-KDPNRPRFTLQELR 300
RA+L K Q ++ +E+ E+E V + AEK DL ++ R L++
Sbjct: 1121 GARAQLLKSLREAQAALAE-AQEDLESERVAR---TKAEKQRRDLGEELEALRGELEDTL 1176
Query: 301 DVLHERNELKSKVFLLQEELAYYKSEEMEEENRI 334
D + + EL+SK +E+ + +EEE RI
Sbjct: 1177 DSTNAQQELRSK----REQEVTELKKTLEEETRI 1206
Score = 48.5 bits (114), Expect = 1e-05
Identities = 75/314 (23%), Positives = 129/314 (41%), Gaps = 25/314 (7%)
Query: 69 SRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQ-DLLSQIAQLQ 127
+R A E + L L + E +DR+E+ R+ ++ EL + E Q L+S + + Q
Sbjct: 1410 ARRRAAREAEALTQRLAE-KTETVDRLERGRRRLQQ-ELDDATMDLEQQRQLVSTLEKKQ 1467
Query: 128 EENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQ--RDEIRAKDRELG 185
+ QL+ + EE + ERE + + + + ++Q R+E+ ++R L
Sbjct: 1468 RKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL- 1526
Query: 186 LKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRA 245
++EAL + + K H+L V E L Q ELE +L E LR
Sbjct: 1527 --RAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAED--AKLRL 1582
Query: 246 ELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDL---KDPNRPRFTLQELRDV 302
E+ + Q E G +E GEE K D +D R + TL
Sbjct: 1583 EVTVQALKTQHERDLQGRDE-----AGEERRRQLAKQLRDAEVERDEERKQRTL-----A 1632
Query: 303 LHERNELKSKVFLLQEELAY--YKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFF 360
+ R +L+ ++ L+ ++A EE ++ R Q R + + + +FS
Sbjct: 1633 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1692
Query: 361 SRDKKRLANTQRNV 374
+KRL + V
Sbjct: 1693 RESEKRLKGLEAEV 1706
Score = 46.2 bits (108), Expect = 5e-05
Identities = 95/394 (24%), Positives = 151/394 (38%), Gaps = 73/394 (18%)
Query: 3 EERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVL- 61
++R A+AA LE + EL + G E + Q R M ++ L
Sbjct: 1627 KQRTLAVAARKKLEGELEELKAQ-----MASAGQGKEEAVKQ------LRKMQAQMKELW 1675
Query: 62 -EILEVLVSRHHVAPELDELR-----LELDRLRLER----MDRIEKERKHQKELELVEDV 111
E+ E SR + + E LE + LRL+ DR ++ + ++ E+ ++V
Sbjct: 1676 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRD-EMADEV 1734
Query: 112 WRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVD 171
G LS+ A L EE +QL L EEE ++ + SE +KL V+
Sbjct: 1735 ANGN----LSKAAIL-EEKRQLEGRLGQL-----EEELEEEQSNSELLNDRYRKLLLQVE 1784
Query: 172 KQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDL---------RHRVTVVEAQGK-A 221
E+ A +R K E QQ + ++ ++ L RH++T+ + K A
Sbjct: 1785 SLTTELSA-ERSFSAKAES--GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLA 1841
Query: 222 LIEQKVELEAD--------------------LQTKEQEM--GSLRAEL--GKLRERLQGE 257
E+++E E LQ +E+ LR +L G LR +
Sbjct: 1842 QAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKR 1901
Query: 258 HSQNGEEEPETEPVGEESIS-DAEKVAMDLKDPNRPRFTLQEL--RDVLHERNELKSKVF 314
+ EEE G + + E V + NR TL+ R L +VF
Sbjct: 1902 QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVF 1961
Query: 315 LLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQ 348
L+E +A + E + P P P P PQ
Sbjct: 1962 RLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 1995
Score = 43.5 bits (101), Expect = 3e-04
Identities = 61/265 (23%), Positives = 118/265 (44%), Gaps = 34/265 (12%)
Query: 87 LRLERMDRIEKERKHQKELELVEDVWRGEAQD---LLSQIAQLQEENKQLMTNLSHKDVN 143
L++ R D + + R +EL+ V+++ + A++ L ++AQL+EE +L L +
Sbjct: 862 LQVTRQDEVLQARA--QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 919
Query: 144 FSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMK 203
+E +E R + K+ ++ E+ A+ +G + E +Q ++ RL +
Sbjct: 920 CAE---------AEETRGRLAARKQELELVVSELEAR---VGEEEECSRQMQTEKKRLQQ 967
Query: 204 INHDLRHRVTVVEAQGKALIEQKVELEA-------DLQTKEQEMGSLRAELGKLRERLQG 256
+L + E + L +KV EA DL E + L E L +RL
Sbjct: 968 HIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE 1027
Query: 257 EHSQNGEEEPETEPVG------EESISDAEKVAMDLKDPNRPRFTLQELRDVLH-ERNEL 309
SQ EEE + + + E +I+D E L+ + R L++L+ L E +EL
Sbjct: 1028 FSSQAAEEEEKVKSLNKLRLKYEATIADMED---RLRKEEKGRQELEKLKRRLDGESSEL 1084
Query: 310 KSKVFLLQEELAYYKSEEMEEENRI 334
+ ++ Q+ +++ +E +
Sbjct: 1085 QEQMVEQQQRAEELRAQLGRKEEEL 1109
Score = 32.0 bits (71), Expect = 1.0
Identities = 57/276 (20%), Positives = 105/276 (38%), Gaps = 11/276 (3%)
Query: 56 KVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGE 115
K +R+ + L ++ H A EL + R+ +E E +E +L E+ E
Sbjct: 1319 KTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLRE-QLEEEAAARE 1377
Query: 116 AQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRD 175
Q AQ Q + + EE ++ +E Q + + E VD+
Sbjct: 1378 RAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLER 1437
Query: 176 EIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQT 235
R +EL D+E +Q + L K + +A +E++ EA+ +
Sbjct: 1438 GRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRE 1497
Query: 236 KEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFT 295
+E SL L + +E + QN E E + +S + V + + R
Sbjct: 1498 REARALSLTRALEEEQEAREELERQNRALRAELEAL----LSSKDDVGKSVHELER---- 1549
Query: 296 LQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEE 331
R N+L+++V L++EL + ++ E
Sbjct: 1550 --ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLE 1583
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 60.1 bits (144), Expect = 3e-09
Identities = 95/401 (23%), Positives = 163/401 (40%), Gaps = 74/401 (18%)
Query: 59 RVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQD 118
R+ E L++LRL+ + + DR+ KE K ++ELE ++ GE+ +
Sbjct: 1065 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1124
Query: 119 LLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERE----RQVMKKLKE----VV 170
L Q+ + Q+ ++L L K EEE Q +E E Q++K L+E +
Sbjct: 1125 LQEQMVEQQQRAEELRAQLGRK-----EEELQAALARAEDEGGARAQLLKSLREAQAALA 1179
Query: 171 DKQRD---------EIRAKDRELGLKNEDVEAL---------------------QQQQTR 200
+ Q D + + R+LG E++EAL +Q+ T
Sbjct: 1180 EAQEDLESERVARTKAEKQRRDLG---EELEALRGELEDTLDSTNAQQELRSKREQEVTE 1236
Query: 201 LMK-INHDLR-HRVTVVEAQ---GKALIEQKVELEADLQTK----------EQEMGSLRA 245
L K + + R H V E + G+AL E +LE + K E E+ LRA
Sbjct: 1237 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1296
Query: 246 ELGKLR-ERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLH 304
EL L+ R +GE + E E G D E+ + + + + EL +V
Sbjct: 1297 ELSSLQTARQEGEQRRRRLELQLQEVQGR--AGDGERARAEAAE--KLQRAQAELENVSG 1352
Query: 305 ERNELKSKVFLLQEELA-----YYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSF 359
NE +SK L +EL+ + ++E+ +E + + R +G++
Sbjct: 1353 ALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1412
Query: 360 FSRDKKRLANTQRNVHIQESFGQWANTHRDD-GYTEQGQEA 399
+ ++R + Q S +W ++ G E G+EA
Sbjct: 1413 EAAARERAGRELQTAQAQLS--EWRRRQEEEAGALEAGEEA 1451
Score = 50.1 bits (118), Expect = 4e-06
Identities = 84/334 (25%), Positives = 144/334 (43%), Gaps = 52/334 (15%)
Query: 2 EEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVL 61
EE RG A + LE V+EL VG E E +R M + L
Sbjct: 965 EETRGRLAARKQELELVVSELEAR--------VGEE----------EECSRQMQTEKKRL 1006
Query: 62 EILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLS 121
+ + H A E +L+L+++ E K +K +++L L+ED
Sbjct: 1007 QQHIQELEAHLEAEEGARQKLQLEKVTTEA-----KMKKFEEDLLLLED----------- 1050
Query: 122 QIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKD 181
Q ++L +E K L L+ +EEE +K + +++ + + ++ D+ R E + +
Sbjct: 1051 QNSKLSKERKLLEDRLAEFSSQAAEEE-EKVKSLNKLRLKYEATIADMEDRLRKEEKGRQ 1109
Query: 182 RELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMG 241
LK L + + L + + + R + AQ L ++ EL+A L E E G
Sbjct: 1110 ELEKLKRR----LDGESSELQEQMVEQQQRAEELRAQ---LGRKEEELQAALARAEDE-G 1161
Query: 242 SLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDL-KDPNRPRFTLQELR 300
RA+L K Q ++ +E+ E+E V + AEK DL ++ R L++
Sbjct: 1162 GARAQLLKSLREAQAALAE-AQEDLESERVAR---TKAEKQRRDLGEELEALRGELEDTL 1217
Query: 301 DVLHERNELKSKVFLLQEELAYYKSEEMEEENRI 334
D + + EL+SK +E+ + +EEE RI
Sbjct: 1218 DSTNAQQELRSK----REQEVTELKKTLEEETRI 1247
Score = 48.5 bits (114), Expect = 1e-05
Identities = 75/314 (23%), Positives = 129/314 (41%), Gaps = 25/314 (7%)
Query: 69 SRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQ-DLLSQIAQLQ 127
+R A E + L L + E +DR+E+ R+ ++ EL + E Q L+S + + Q
Sbjct: 1451 ARRRAAREAEALTQRLAE-KTETVDRLERGRRRLQQ-ELDDATMDLEQQRQLVSTLEKKQ 1508
Query: 128 EENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQ--RDEIRAKDRELG 185
+ QL+ + EE + ERE + + + + ++Q R+E+ ++R L
Sbjct: 1509 RKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL- 1567
Query: 186 LKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRA 245
++EAL + + K H+L V E L Q ELE +L E LR
Sbjct: 1568 --RAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAED--AKLRL 1623
Query: 246 ELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDL---KDPNRPRFTLQELRDV 302
E+ + Q E G +E GEE K D +D R + TL
Sbjct: 1624 EVTVQALKTQHERDLQGRDE-----AGEERRRQLAKQLRDAEVERDEERKQRTL-----A 1673
Query: 303 LHERNELKSKVFLLQEELAY--YKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFF 360
+ R +L+ ++ L+ ++A EE ++ R Q R + + + +FS
Sbjct: 1674 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1733
Query: 361 SRDKKRLANTQRNV 374
+KRL + V
Sbjct: 1734 RESEKRLKGLEAEV 1747
Score = 46.2 bits (108), Expect = 5e-05
Identities = 95/394 (24%), Positives = 151/394 (38%), Gaps = 73/394 (18%)
Query: 3 EERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVL- 61
++R A+AA LE + EL + G E + Q R M ++ L
Sbjct: 1668 KQRTLAVAARKKLEGELEELKAQ-----MASAGQGKEEAVKQ------LRKMQAQMKELW 1716
Query: 62 -EILEVLVSRHHVAPELDELR-----LELDRLRLER----MDRIEKERKHQKELELVEDV 111
E+ E SR + + E LE + LRL+ DR ++ + ++ E+ ++V
Sbjct: 1717 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRD-EMADEV 1775
Query: 112 WRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVD 171
G LS+ A L EE +QL L EEE ++ + SE +KL V+
Sbjct: 1776 ANGN----LSKAAIL-EEKRQLEGRLGQL-----EEELEEEQSNSELLNDRYRKLLLQVE 1825
Query: 172 KQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDL---------RHRVTVVEAQGK-A 221
E+ A +R K E QQ + ++ ++ L RH++T+ + K A
Sbjct: 1826 SLTTELSA-ERSFSAKAES--GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLA 1882
Query: 222 LIEQKVELEAD--------------------LQTKEQEM--GSLRAEL--GKLRERLQGE 257
E+++E E LQ +E+ LR +L G LR +
Sbjct: 1883 QAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKR 1942
Query: 258 HSQNGEEEPETEPVGEESIS-DAEKVAMDLKDPNRPRFTLQEL--RDVLHERNELKSKVF 314
+ EEE G + + E V + NR TL+ R L +VF
Sbjct: 1943 QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVF 2002
Query: 315 LLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQ 348
L+E +A + E + P P P P PQ
Sbjct: 2003 RLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2036
Score = 43.5 bits (101), Expect = 3e-04
Identities = 61/265 (23%), Positives = 118/265 (44%), Gaps = 34/265 (12%)
Query: 87 LRLERMDRIEKERKHQKELELVEDVWRGEAQD---LLSQIAQLQEENKQLMTNLSHKDVN 143
L++ R D + + R +EL+ V+++ + A++ L ++AQL+EE +L L +
Sbjct: 903 LQVTRQDEVLQARA--QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960
Query: 144 FSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMK 203
+E +E R + K+ ++ E+ A+ +G + E +Q ++ RL +
Sbjct: 961 CAE---------AEETRGRLAARKQELELVVSELEAR---VGEEEECSRQMQTEKKRLQQ 1008
Query: 204 INHDLRHRVTVVEAQGKALIEQKVELEA-------DLQTKEQEMGSLRAELGKLRERLQG 256
+L + E + L +KV EA DL E + L E L +RL
Sbjct: 1009 HIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE 1068
Query: 257 EHSQNGEEEPETEPVG------EESISDAEKVAMDLKDPNRPRFTLQELRDVLH-ERNEL 309
SQ EEE + + + E +I+D E L+ + R L++L+ L E +EL
Sbjct: 1069 FSSQAAEEEEKVKSLNKLRLKYEATIADMED---RLRKEEKGRQELEKLKRRLDGESSEL 1125
Query: 310 KSKVFLLQEELAYYKSEEMEEENRI 334
+ ++ Q+ +++ +E +
Sbjct: 1126 QEQMVEQQQRAEELRAQLGRKEEEL 1150
Score = 32.0 bits (71), Expect = 1.0
Identities = 57/276 (20%), Positives = 105/276 (38%), Gaps = 11/276 (3%)
Query: 56 KVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGE 115
K +R+ + L ++ H A EL + R+ +E E +E +L E+ E
Sbjct: 1360 KTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLRE-QLEEEAAARE 1418
Query: 116 AQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRD 175
Q AQ Q + + EE ++ +E Q + + E VD+
Sbjct: 1419 RAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLER 1478
Query: 176 EIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQT 235
R +EL D+E +Q + L K + +A +E++ EA+ +
Sbjct: 1479 GRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRE 1538
Query: 236 KEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFT 295
+E SL L + +E + QN E E + +S + V + + R
Sbjct: 1539 REARALSLTRALEEEQEAREELERQNRALRAELEAL----LSSKDDVGKSVHELER---- 1590
Query: 296 LQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEE 331
R N+L+++V L++EL + ++ E
Sbjct: 1591 --ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLE 1624
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 60.1 bits (144), Expect = 3e-09
Identities = 84/350 (24%), Positives = 155/350 (44%), Gaps = 43/350 (12%)
Query: 1 MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRV 60
++EE G+ + LEK AE + + + L+ + + I + +LM R+
Sbjct: 959 LDEEEGARQKLQ--LEKVTAEAKIKKMEEEILLLEDQNSKFIKEK------KLMED--RI 1008
Query: 61 LEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLL 120
E L A L ++R + + + + +R++KE K ++ELE + GE DL
Sbjct: 1009 AECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQ 1068
Query: 121 SQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAK 180
QIA+LQ + +L L+ K EEE Q + E +VV E++A+
Sbjct: 1069 DQIAELQAQIDELKLQLAKK-----EEELQGALARGDDETLHKNNALKVV----RELQAQ 1119
Query: 181 DRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQT--KEQ 238
EL ED E+ + + + K DL + + K ELE L T +Q
Sbjct: 1120 IAEL---QEDFESEKASRNKAEKQKRDLSEELEAL----------KTELEDTLDTTAAQQ 1166
Query: 239 EMGSLR-AELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQ 297
E+ + R E+ +L++ L+ E ++N E + + + + + E+++ L+ R + L+
Sbjct: 1167 ELRTKREQEVAELKKALE-EETKN--HEAQIQDMRQRHATALEELSEQLEQAKRFKANLE 1223
Query: 298 ELRDVLHERN-ELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTS 346
+ + L N EL +V +LQ+ K+E + ++ H + S
Sbjct: 1224 KNKQGLETDNKELACEVKVLQQ----VKAESEHKRKKLDAQVQELHAKVS 1269
Score = 50.8 bits (120), Expect = 2e-06
Identities = 88/390 (22%), Positives = 165/390 (42%), Gaps = 75/390 (19%)
Query: 1 MEEERGSALAAESALEKNVAELTVMD--VYDIASLVGHEFERVIDQHGCEAIARLMPKV- 57
MEEE L E K + E +M+ + + +S + E E+ + +A++ K
Sbjct: 983 MEEE---ILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKA------KNLAKIRNKQE 1033
Query: 58 VRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEK------ERKHQ---KELELV 108
V + ++ E L EL++ + +LD + D+I + E K Q KE EL
Sbjct: 1034 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ 1093
Query: 109 EDVWRGE------------AQDLLSQIAQLQE--ENKQLMTNLSHKDVNFSEEEFQ---- 150
+ RG+ ++L +QIA+LQE E+++ N + K EE +
Sbjct: 1094 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT 1153
Query: 151 -----------KHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNED-VEALQQQQ 198
+ E ++RE++V + LK+ ++++ A+ +++ ++ +E L +Q
Sbjct: 1154 ELEDTLDTTAAQQELRTKREQEVAE-LKKALEEETKNHEAQIQDMRQRHATALEELSEQL 1212
Query: 199 TRLMKINHDLRHRVTVVEAQGKAL-----IEQKVELEAD------------LQTKEQEMG 241
+ + +L +E K L + Q+V+ E++ L K E
Sbjct: 1213 EQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGD 1272
Query: 242 SLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRD 301
LR EL + +LQ E E E G + DA + L+D T + L++
Sbjct: 1273 RLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQD------TQELLQE 1326
Query: 302 VLHERNELKSKVFLLQEELAYYKSEEMEEE 331
++ L S++ L+EE + ++ EEE
Sbjct: 1327 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEE 1356
Score = 48.9 bits (115), Expect = 8e-06
Identities = 82/405 (20%), Positives = 169/405 (41%), Gaps = 37/405 (9%)
Query: 1 MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGC-EAIARLMPKVVR 59
+EEE+ S L + E+ + V + S + ++V D G E++ K+++
Sbjct: 1341 LEEEKNS-LQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLK 1399
Query: 60 VLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDL 119
E L + +A D+L +RL+ E +D + + HQ+++
Sbjct: 1400 DAEALSQRLEEKALA--YDKLEKTKNRLQQE-LDDLTVDLDHQRQVA------------- 1443
Query: 120 LSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVM---KKLKEVVDKQRDE 176
S + + Q++ QL+ ++EE + E+E + + + L+E ++ ++E
Sbjct: 1444 -SNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEA-KEE 1501
Query: 177 IRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTK 236
++++L D+E L + + K H+L +E Q + + Q ELE +LQ
Sbjct: 1502 FERQNKQL---RADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
Query: 237 EQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTL 296
E LR E+ + Q E +E + E I ++ +L+D + R
Sbjct: 1559 ED--AKLRLEVNMQAMKAQFERDLQTRDE-QNEEKKRLLIKQVRELEAELEDERKQR--- 1612
Query: 297 QELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRL 356
L ++ E+ K Q E A +E+ ++ R Q + R + + +
Sbjct: 1613 -ALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEI 1671
Query: 357 FSFFSRDKKRLANTQRNV-HIQESFGQWANTHRDDGYTEQGQEAL 400
F+ +K+L + + + +QE + A++ R + EQ ++ L
Sbjct: 1672 FAQSKESEKKLKSLEAEILQLQE---ELASSERARRHAEQERDEL 1713
Score = 45.4 bits (106), Expect = 9e-05
Identities = 81/374 (21%), Positives = 163/374 (43%), Gaps = 54/374 (14%)
Query: 3 EERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLE 62
EER A A A EK L++ + A EFER Q + + K
Sbjct: 1469 EERDRAEA--EAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKN 1526
Query: 63 ILEVLVSRHHVAPELDELRLELD------------RLRLERMDRIEKERKHQKELELVED 110
+ E+ S+ + +++E+R +L+ +LRLE ++ + + +++L+ ++
Sbjct: 1527 VHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLE-VNMQAMKAQFERDLQTRDE 1585
Query: 111 VWRGEAQDLLSQI----AQLQEENKQLMTNLSHK---DVNFSEEEFQKHEGMSERERQVM 163
+ + L+ Q+ A+L++E KQ ++ K +++ + E Q R+ +V+
Sbjct: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARD-EVI 1644
Query: 164 KKLK-------------EVVDKQRDEIRAKDRELGLKNEDVEA-LQQQQTRLMKINHDLR 209
K+L+ E RDEI A+ +E K + +EA + Q Q L R
Sbjct: 1645 KQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARR 1704
Query: 210 H----------RVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHS 259
H +T + AL+++K LEA + E+E+ ++ + L +R +
Sbjct: 1705 HAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTL 1764
Query: 260 QNGEEEPETEPVGEESISD-AEKVAMDLKDPNRP-RFTLQELRDVLHERNELKSKVFLLQ 317
Q + E E S + ++ L+ N+ + LQEL + +++ K+ + L+
Sbjct: 1765 Q--VDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV--KSKFKATISALE 1820
Query: 318 EELAYYKSEEMEEE 331
++ + E++E+E
Sbjct: 1821 AKIGQLE-EQLEQE 1833
Score = 41.2 bits (95), Expect = 0.002
Identities = 62/308 (20%), Positives = 123/308 (39%), Gaps = 47/308 (15%)
Query: 65 EVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIA 124
E+ + L + EL+ + + R+E+E + + L+ + + QDL Q+
Sbjct: 901 ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960
Query: 125 QLQ--EENKQLMTNLSHKDVNFSEEE----------FQKHEGMSE-----------RERQ 161
+ + + QL + + EEE F K + + E E +
Sbjct: 961 EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
Query: 162 VMKKLKEVVDKQRDEIRAKDRELGLKNEDV--EALQQQQTRLMKINHDLRHRVTVVEAQG 219
K L ++ +KQ E+ D E LK E+ + L++ + +L DL+ ++ ++AQ
Sbjct: 1021 KAKNLAKIRNKQ--EVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 220 KALIEQKVELEADLQ--------------TKEQEMGSLRAELGKLRERLQGEHSQNGEEE 265
L Q + E +LQ + + L+A++ +L+E + E + + E
Sbjct: 1079 DELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAE 1138
Query: 266 PETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKS 325
+ + EE E + +L+D QELR E+ L+EE +++
Sbjct: 1139 KQKRDLSEE----LEALKTELEDTLDTTAAQQELR--TKREQEVAELKKALEEETKNHEA 1192
Query: 326 EEMEEENR 333
+ + R
Sbjct: 1193 QIQDMRQR 1200
Score = 40.8 bits (94), Expect = 0.002
Identities = 59/256 (23%), Positives = 113/256 (44%), Gaps = 33/256 (12%)
Query: 96 EKERKHQKELELVEDVWR--GEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHE 153
E + K ++ L++ E + GE +++ + QL EE L L + F+E E
Sbjct: 853 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAE----- 907
Query: 154 GMSERERQVMKKLKEVVDKQRD-EIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRV 212
E ++ K +E+ + D E R ++ E E + LQ ++ ++ DL ++
Sbjct: 908 ---EMRARLAAKKQELEEILHDLESRVEEEE-----ERNQILQNEKKKMQAHIQDLEEQL 959
Query: 213 TVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGK-------LRERLQGEHSQNGEEE 265
E + L +KV EA ++ E+E+ L + K + +R+ SQ EEE
Sbjct: 960 DEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEE 1019
Query: 266 PETEPVG------EESISDAEKVAMDLKDPNRPRFTLQELRDVLH-ERNELKSKVFLLQE 318
+ + + E ISD E+ LK + R L++ + L E +L+ ++ LQ
Sbjct: 1020 EKAKNLAKIRNKQEVMISDLEE---RLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQA 1076
Query: 319 ELAYYKSEEMEEENRI 334
++ K + ++E +
Sbjct: 1077 QIDELKLQLAKKEEEL 1092
Score = 38.9 bits (89), Expect = 0.008
Identities = 71/309 (22%), Positives = 120/309 (38%), Gaps = 74/309 (23%)
Query: 48 EAIARLMPKVVRVLEILEVLVS----RHHVAPELDELRLEL------------DRLRLE- 90
E+ +L +L++ E L S R H E DEL E+ ++ RLE
Sbjct: 1677 ESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEA 1736
Query: 91 RMDRIEKE-RKHQKELELVEDVWRG---EAQDLLSQIA--------------QLQEENKQ 132
R+ ++E+E + Q +EL+ D +R + L +++A QL+ +NK+
Sbjct: 1737 RIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKE 1796
Query: 133 LMTNL---------------SHKDVNFSEEEFQKHEGMSERE------RQVMKKLKEVVD 171
L L S + + E Q + ER R+ KKLKE+
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 172 KQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEA 231
+ DE R D + E +++ R+ ++ L EA +K++ E
Sbjct: 1857 QVEDERRHAD-------QYKEQMEKANARMKQLKRQLEE--AEEEATRANASRRKLQREL 1907
Query: 232 DLQTKEQEMGSLRAELGKLRERLQG------EHSQNGEEEPETEPVG-EESISDAEKVAM 284
D T+ E L E+ L+ RL+ S++G + E E S D E
Sbjct: 1908 DDATEANE--GLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTS 1965
Query: 285 DLKDPNRPR 293
D+ + P+
Sbjct: 1966 DVNETQPPQ 1974
Score = 38.1 bits (87), Expect = 0.014
Identities = 75/309 (24%), Positives = 121/309 (39%), Gaps = 44/309 (14%)
Query: 43 DQHGCEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLEL-------DRLRLERMDRI 95
++ G E + + V+VL+ +V H +LD EL DRLR+E
Sbjct: 1225 NKQGLETDNKELACEVKVLQ--QVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELA--- 1279
Query: 96 EKERKHQKELELVEDVWRGE-------AQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEE 148
EK K Q EL+ V + A+D S +QLQ+ + L +EE
Sbjct: 1280 EKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELL------------QEE 1327
Query: 149 FQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQ-QTRLMKINHD 207
++ +S R RQ+ ++ + ++Q +E A+ + V ALQ Q K++ D
Sbjct: 1328 TRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN----LEKQVLALQSQLADTKKKVDDD 1383
Query: 208 LRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPE 267
L ++ EA+ K L + + L + +E +L K + RLQ E +
Sbjct: 1384 LGTIESLEEAKKKLLKDAEA-----LSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDH 1438
Query: 268 TEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLH-ERNELKSKVFLLQEEL--AYYK 324
V +K L + E RD E E ++K L L A
Sbjct: 1439 QRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEA 1498
Query: 325 SEEMEEENR 333
EE E +N+
Sbjct: 1499 KEEFERQNK 1507
>gi|190194355 p90 autoantigen [Homo sapiens]
Length = 905
Score = 59.7 bits (143), Expect = 5e-09
Identities = 61/276 (22%), Positives = 119/276 (43%), Gaps = 40/276 (14%)
Query: 21 ELTVMDVYDIASLVGHEFERVIDQHGCE---------AIARLMPKVVRVLEILEVLVSRH 71
E + D+ + +L + +R+I QH C+ +A ++ +V R E L VL+
Sbjct: 637 ESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQ 696
Query: 72 HVAPELDELRLE------------------LDRLRLERMDRIEKERKHQKELELVEDVWR 113
V E + +E L + +E + R E K K+L++ D
Sbjct: 697 QVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLN 756
Query: 114 GEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQ 173
+ + + L+E+N++ + L K+ E+ + + +RE + + L + Q
Sbjct: 757 KQIETVKKLNESLKEQNEKSIAQLIEKE----EQRKEVQNQLVDREHK-LANLHQKTKVQ 811
Query: 174 RDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADL 233
++I+ +E K E ++ L+++ +R +I +L + + +E QK +LE L
Sbjct: 812 EEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEV-------QKAQLEGRL 864
Query: 234 QTKEQEMGSLRAELGKLRERLQGEHS-QNGEEEPET 268
+ KE + + EL K + HS G+ PET
Sbjct: 865 EEKESLVKLQQEELNKHSHMIAMIHSLSGGKINPET 900
Score = 49.7 bits (117), Expect = 5e-06
Identities = 57/270 (21%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 58 VRVLEILEVLVSR-HHVAPELDELR--LELDRLRLERMDRIEKERKHQKELELVEDVWRG 114
VR+ +I++V + +A + L+ LE L L + DR+ + + Q+
Sbjct: 617 VRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQA------ET 670
Query: 115 EAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQ-KHEGMSERERQVMKKLKEVVDKQ 173
EA+ L S + +++ +N++L L + V + +H R+ + + + E++ K
Sbjct: 671 EARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKS 730
Query: 174 RDEIRAKDRELGLKNEDVE----ALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVEL 229
E+ ++ KN+D++ +L +Q + K+N L+ + AQ EQ+ E+
Sbjct: 731 YMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEV 790
Query: 230 EADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDP 289
+ L +E ++ +L + E+++ + E++ ET + + +S E++ +L
Sbjct: 791 QNQLVDREHKLANLHQKTKVQEEKIKTLQKER-EDKEETIDILRKELSRTEQIRKEL--- 846
Query: 290 NRPRFTLQELRDVLHERNELKSKVFLLQEE 319
+ +L+ + L R E K + LQ+E
Sbjct: 847 SIKASSLEVQKAQLEGRLEEKESLVKLQQE 876
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 59.7 bits (143), Expect = 5e-09
Identities = 77/321 (23%), Positives = 141/321 (43%), Gaps = 49/321 (15%)
Query: 41 VIDQHGCEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLEL------DRLRLERMDR 94
++ Q E+IA PK L E + +A E D+ + E+ + R
Sbjct: 134 LVFQGAVESIAMKNPKERTAL--FEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKN 191
Query: 95 IEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEG 154
I ERK K+ + D ++ +++ QLQ + L H +V E+ K
Sbjct: 192 IAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQ------LFKLYHNEVEI--EKLNKELA 243
Query: 155 MSERERQVMKKLKEVVDKQRDEIRAKDRELG------------LKNEDVEALQQQQTRLM 202
+E ++K K+ +DK DE++ K +ELG +K +D E L Q++ + +
Sbjct: 244 SKNKE---IEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSE-LNQKRPQYI 299
Query: 203 KINHDLRHRVTVVEAQGKALIEQK---VELEADLQTKEQEMGSLRAELGKLRERLQGEHS 259
K + H++ +EA K+L + + + D+ E+EM S+ + ER++ E
Sbjct: 300 KAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQ 359
Query: 260 QNGE----EEPETEP---VGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSK 312
G EE + + + EE+ A +A +L+ NR + Q+ D L ER +++++
Sbjct: 360 SQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLD-LEERKKVETE 418
Query: 313 VFLLQEELAYYKSEEMEEENR 333
+ Q K E+EE +
Sbjct: 419 AKIKQ------KLREIEENQK 433
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 59.7 bits (143), Expect = 5e-09
Identities = 73/315 (23%), Positives = 141/315 (44%), Gaps = 52/315 (16%)
Query: 79 ELRLELDRLRLE--RMDRIEKERKHQKELELVE---------DVWRGEAQDLLSQIA--- 124
E++ E +R ++E R + E+ R Q EL L+E + W ++ I
Sbjct: 178 EVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKT 237
Query: 125 ----------------QLQEENKQLMTNLSH-KDVNFSE-----EEFQKHEGMSERERQV 162
+L EE+++ M L + + F+E E + + M E+E QV
Sbjct: 238 KPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQV 297
Query: 163 MKKLKEVVDKQRDEIRAKDREL---GLKNEDVE---ALQQQQTRLMKINHDLRHRVTVVE 216
++ ++ +++ ++ ++ EL G ++ DVE A ++++ + ++ D E
Sbjct: 298 VRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQE--E 355
Query: 217 AQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQG-EHSQNGEEEPETEPVGEES 275
+ K +E K+E E +++ E++ S E+ + E ++ +H +E ET V ES
Sbjct: 356 EEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRV--ES 413
Query: 276 ISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIP 335
+ +E A +P F ++ ++ + K V L E +SEE EE+ P
Sbjct: 414 VEPSENEASKELEPEM-EFEIEPDKEC-KSLSPGKENVSALDMEK---ESEEKEEKESEP 468
Query: 336 QPPPIAHPRTSPQPE 350
QP P+A P+ QP+
Sbjct: 469 QPEPVAQPQPQSQPQ 483
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 59.3 bits (142), Expect = 6e-09
Identities = 69/295 (23%), Positives = 128/295 (43%), Gaps = 38/295 (12%)
Query: 48 EAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDR--IEKERK---HQ 102
E++++ K+ ++L+ L+ L DE +L + +++ +M R KER+ Q
Sbjct: 2064 ESLSKEPAKLNKILKALQKLTR--------DERKLTQEEIKMTKMKRALFVKERRLSIEQ 2115
Query: 103 KELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQV 162
+L++ E W D + ++L ++ K+L K N K E M+E E ++
Sbjct: 2116 SKLDIKE--W-----DFSEKRSELTKDEKKLARK-QRKLANKMRRMINKEEKMTEEESKL 2167
Query: 163 MKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKI-----NHDLRHRVTVVEA 217
+K EV I + E G++ E+V +++ R K + V E
Sbjct: 2168 ARKHSEV-------ILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEV 2220
Query: 218 QGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESIS 277
+ + +++E D K++ + S E + E + E + EEE + E GEE
Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV 2280
Query: 278 DAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEEN 332
+ E+ K + + +QE +V E+ E+ S +EE EE EEE+
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMS-----EEETESLSDEEEEEES 2330
Score = 51.6 bits (122), Expect = 1e-06
Identities = 61/270 (22%), Positives = 120/270 (44%), Gaps = 31/270 (11%)
Query: 65 EVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIA 124
+V + H+ E R+ R R E+ R ++ERK +E E L +
Sbjct: 1560 QVTEEQRHIQEEHKWARIHRKRARAEK-KRAQEERKLAQEEE-----------KLAQEER 1607
Query: 125 QLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDREL 184
QL +E ++L ++ + + E + EG ++ + + + E + ++ +++ K ++L
Sbjct: 1608 QLAQEERKLAQ--AYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKL 1665
Query: 185 GLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLR 244
K E V +++ +L K L A+ K ++ QKVE +L +EQ +
Sbjct: 1666 AKKWEKV---AREEEKLAKKGGKL--------AEVKNILAQKVE---ELPQREQNLDWQE 1711
Query: 245 AELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLH 304
EL + E L+ + + +E E + + + +K+A + + R L E L
Sbjct: 1712 KELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLA 1771
Query: 305 ERNELKSKVFLLQEELAYYKSEEMEEENRI 334
+ EL + +E+LA +K + EEE R+
Sbjct: 1772 QEEEL---LIQEKEKLAQHKEKMPEEEERL 1798
Score = 45.8 bits (107), Expect = 7e-05
Identities = 59/253 (23%), Positives = 114/253 (45%), Gaps = 22/253 (8%)
Query: 48 EAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELEL 107
E + M ++ LE E L S E +E R E + +R E +R E+E +K++E
Sbjct: 2224 EHFSEEMESLLDELEKQESLSSEEEEEREEEEEREE-EEVREEEEERKEEEEGEEKQVEK 2282
Query: 108 VEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLK 167
E+ + + ++ + Q +EE K+ SEEE + E E + L+
Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEE------VFEEKEEIMSEEETESLS--DEEEEEESCSLE 2334
Query: 168 EVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRH------RVTVVEAQGKA 221
E VD+++ EI K+++ L+ + ++L+ ++ R++ I + H R+ V+++ K
Sbjct: 2335 EEVDREK-EILKKEKQFKLQEQRRKSLRGRE-RVLSILRGVPHGKGRAIRLGVLKSPLKK 2392
Query: 222 L----IEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESIS 277
L +E K + + K+ +A + ++ + G + E + EP+ +
Sbjct: 2393 LMSTALEMKEKTPVPVPEKQISWEDKKATVVEIPRKFLGTMDKEREVMGKYEPIPPHVLG 2452
Query: 278 DA-EKVAMDLKDP 289
E A DLK P
Sbjct: 2453 TVLESQAQDLKTP 2465
Score = 42.0 bits (97), Expect = 0.001
Identities = 72/353 (20%), Positives = 141/353 (39%), Gaps = 55/353 (15%)
Query: 80 LRLELDRLRLERMDRIEKERKHQKELELVED---VWRGEAQDLLSQIAQLQEENKQLMTN 136
LR ELD + E+ +E +R ++++ LVE + +GE + Q Q E +
Sbjct: 1950 LRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERK 2009
Query: 137 LS-------HKDVNFSEEEFQKHEG-----------------MSERERQVMKKLKEVVDK 172
LS H+D + EE + +G +++ R+++KK +E + K
Sbjct: 2010 LSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKK-RESLSK 2068
Query: 173 QRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDL---RHRVTVVEAQGKALIEQKVEL 229
+ ++ + L D L Q++ ++ K+ L R+++ +++ E
Sbjct: 2069 EPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEK 2128
Query: 230 EADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISD--------AEK 281
++L E+++ + +L R+ + + EEE + E I D E+
Sbjct: 2129 RSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEE 2188
Query: 282 VAMDLK------------DPNRPRFTLQ--ELRDVLHERNELKSKVFLL--QEELAYYKS 325
V LK D + +F+ Q E+ H E++S + L QE L+ +
Sbjct: 2189 VIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEE 2248
Query: 326 EEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFFSRDKKRLANTQRNVHIQE 378
EE EEE + + E G ++ +KK+ ++ +QE
Sbjct: 2249 EEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQE 2301
Score = 41.2 bits (95), Expect = 0.002
Identities = 66/338 (19%), Positives = 148/338 (43%), Gaps = 39/338 (11%)
Query: 96 EKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSH-----KDVNFSEEEFQ 150
EK K +L V+++ + ++L + L + K+L L +++++ EEE
Sbjct: 1677 EKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELN 1736
Query: 151 KHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRH 210
+ EG E++ + + +E + QR+++ ++ +L ++ E L Q++ +L + +
Sbjct: 1737 QEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLA---QEEELLIQEKEKLAQHKEKMPE 1793
Query: 211 RVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGK------LRERLQGEHSQNGEE 264
+ + + LIE+K++L Q +E+ + S+ EL K ++ L E +E
Sbjct: 1794 EEERLGRKREQLIEKKMKL---AQKRERWINSME-ELTKNKMILYQKKNLAQEKKNLAQE 1849
Query: 265 EPETEPVGEESISDAEKVAMDLKDPNRPRFTL---------------QELRDVLHERNEL 309
+ + E + + E++ K + + L QE V+ ++ +L
Sbjct: 1850 KEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKL 1909
Query: 310 ---KSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFFSRDKKR 366
+ K+ +++ LA + + +E+ ++ + + + E I + + + KR
Sbjct: 1910 AETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKR 1969
Query: 367 LANTQ-RNVHIQE--SFGQWANTHRDDGYTEQGQEALQ 401
LA + R V +E S G+ T R T+ QE +
Sbjct: 1970 LAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFE 2007
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 59.3 bits (142), Expect = 6e-09
Identities = 55/271 (20%), Positives = 128/271 (47%), Gaps = 25/271 (9%)
Query: 76 ELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMT 135
E E++L + L+ +++R + + L E++WR E ++L Q +++++ +++
Sbjct: 240 EKSEIQLNVKELK-RKLERAKFLLPQVQTNTLQEEMWRQE-EELREQEKKIRKQEEKMWR 297
Query: 136 NLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLK---NEDVE 192
EE ++ EG + + M + ++ + +Q E+R +++EL + E E
Sbjct: 298 Q---------EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEE 348
Query: 193 ALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRE 252
+Q+Q+ ++ + +R + + Q + L EQ E ++ +EQ+M + + E
Sbjct: 349 QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ----EKQMREQEQKMRDQEERMWEQDE 404
Query: 253 RLQGEHSQNGEEEPETEPV----GEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNE 308
RL+ + + E+E E V E+ + + EK D ++ + ++E + E E
Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464
Query: 309 L---KSKVFLLQEELAYYKSEEMEEENRIPQ 336
+ + QEE + + E+ ++ R+P+
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPE 495
Score = 59.3 bits (142), Expect = 6e-09
Identities = 54/258 (20%), Positives = 128/258 (49%), Gaps = 27/258 (10%)
Query: 90 ERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEF 149
++M R EK R+ + ++ E+ R + Q + Q EE + T K EE+
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ-----EERMEKKTQEQEKKTWDQEEKM 585
Query: 150 QKHEGMSERER------QVMKKLKEVVDKQRDEIRAKDRELGLKNEDV----EALQQQQT 199
++ E M ERE+ ++M++ +E + +Q ++++ ++ ++ + E + E + +Q+
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Query: 200 RLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHS 259
++ + + + + E + K +K++ + +Q +E+++ E K+ ++ Q +
Sbjct: 646 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIW----EQEKMEKKTQEQEK 701
Query: 260 QNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFT-LQELRDVLHERNELKSKVFLLQE 318
+ ++E E EES+ + EK + ++ R + +QE + + E+ E + QE
Sbjct: 702 KTWDQEKMRE---EESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE----QE 754
Query: 319 ELAYYKSEEMEEENRIPQ 336
E + + E+M E+ R+P+
Sbjct: 755 EKMWEQEEKMWEQQRLPE 772
Score = 55.1 bits (131), Expect = 1e-07
Identities = 55/260 (21%), Positives = 130/260 (50%), Gaps = 17/260 (6%)
Query: 75 PELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLM 134
PE E E ++++ + E+E K + + E++W G+ + + Q ++E++ M
Sbjct: 494 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ----EEMW-GQEKKMWRQEKMREQEDQ--M 546
Query: 135 TNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEAL 194
K + ++ + + E M ++ ++ KK + +K R+E R ++RE ++ E+ E +
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE-EMM 605
Query: 195 QQQQTRLMKINHDLRHRVTVVEAQGKALIEQKV---ELEADLQTKEQEMGSLRAELGKLR 251
++Q+ ++ + ++ + + Q + + EQ+ E E + +E++M + L + +
Sbjct: 606 REQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWE-QQRLPEQK 664
Query: 252 ERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKS 311
E+L EH + E+E E EE I + EK+ ++ + + +++R+ E +
Sbjct: 665 EKL-WEHEKMQEQEKMQEQ--EEKIWEQEKMEKKTQEQEKKTWDQEKMRE--EESMRERE 719
Query: 312 KVFLLQEELAYYKSEEMEEE 331
K +EE+ + E+M+E+
Sbjct: 720 KKMREEEEMMREQEEKMQEQ 739
Score = 53.9 bits (128), Expect = 3e-07
Identities = 70/297 (23%), Positives = 137/297 (46%), Gaps = 26/297 (8%)
Query: 39 ERVIDQHGC--EAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIE 96
ER+ +Q G E ++ + R+ E + L + E ELR + ++++ + E
Sbjct: 300 ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWE 359
Query: 97 KERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMS 156
+E K +++ E +WR E + L Q Q++E+ +Q M + + E +K E M
Sbjct: 360 QEEKMREQ---EEKMWRQEER-LWEQEKQMREQ-EQKMRDQEERMWEQDERLREKEERMR 414
Query: 157 ERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVE 216
E+E K+ E V+K R+E + +++E K D E Q++ R+ + +R +
Sbjct: 415 EQE-----KMWEQVEKMREEKKMQEQE--KKTRDQEEKMQEEERIREREKKMREEEETMR 467
Query: 217 AQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESI 276
Q E+K++ + + +++E + L + +E+L + +EE E EE I
Sbjct: 468 EQ-----EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ--EEKI 520
Query: 277 SDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENR 333
D E++ K R ++E D + E+ E QE+ + + E ME++ +
Sbjct: 521 RDQEEMWGQEKKMWRQE-KMREQEDQMWEQEEKMRD----QEQKMWDQEERMEKKTQ 572
Score = 49.3 bits (116), Expect = 6e-06
Identities = 54/278 (19%), Positives = 131/278 (47%), Gaps = 35/278 (12%)
Query: 90 ERMDRIEKERKHQKELELVEDVWRGEAQDLL-SQIAQLQEENKQLMTNLSHKDVNFSEEE 148
E+ R ++ER +++ L E R Q+ + Q+ +++EE K +D EE+
Sbjct: 389 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD---QEEK 445
Query: 149 FQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNE----------------DVE 192
Q+ E + ERE++ M++ +E + +Q ++++ ++ + + E + E
Sbjct: 446 MQEEERIREREKK-MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 504
Query: 193 ALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKV-ELEADLQTKEQEMGSLRAELGKLR 251
+Q+Q+ ++ + +R + + + K ++K+ E E + +E++M ++
Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564
Query: 252 ERLQGEHSQNGEE--EPETEPVGEESISDAEKVAMDLKDPNRPRFT-LQELRDVLHERNE 308
ER++ + + ++ + E + EE + + EK + ++ R + +QE + + E+ E
Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624
Query: 309 L----------KSKVFLLQEELAYYKSEEMEEENRIPQ 336
+ + QEE + + E+M E+ R+P+
Sbjct: 625 KMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662
Score = 48.5 bits (114), Expect = 1e-05
Identities = 51/245 (20%), Positives = 121/245 (49%), Gaps = 24/245 (9%)
Query: 90 ERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEF 149
E+M E+ R+ +K++ E++ R + + + Q ++QE+ +++ EE+
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQ---------EEKM 633
Query: 150 QKHEG-MSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDL 208
Q+ E M E+E ++ ++ +++ ++QR + +E ++E ++ ++ Q + KI
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQR---LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 209 RHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPET 268
+ E + K ++K+ E ++ +E++M R E +RE Q E Q EE+ +
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKM---REEEEMMRE--QEEKMQEQEEKMQE 745
Query: 269 EPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEM 328
+ EE + + E+ + ++ + L E ++ L E +++ + + ++E K +
Sbjct: 746 Q---EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQE---EKMRDQ 799
Query: 329 EEENR 333
EE+ R
Sbjct: 800 EEKMR 804
Score = 39.7 bits (91), Expect = 0.005
Identities = 40/223 (17%), Positives = 106/223 (47%), Gaps = 13/223 (5%)
Query: 52 RLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDV 111
R+ + ++ E E++ + E +E E + E+ ++++++ + E E E +
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE--EKM 647
Query: 112 WRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVD 171
W E ++ + + +L E+ ++L + ++ +E+ +K + E++ ++ K+ D
Sbjct: 648 W--EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD 705
Query: 172 --KQRDEIRAKDRELGLKNEDV------EALQQQQTRLMKINHDLRHRVTVVEAQGKALI 223
K R+E ++RE ++ E+ E +Q+Q+ ++ + ++ + + Q + +
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMW 765
Query: 224 EQKVELEADLQTKEQEMGSLRAELGKLRERLQG-EHSQNGEEE 265
EQ+ E + E E + ++ + E+++ E G+EE
Sbjct: 766 EQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEE 808
Score = 38.5 bits (88), Expect = 0.011
Identities = 34/193 (17%), Positives = 89/193 (46%), Gaps = 15/193 (7%)
Query: 90 ERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEF 149
E+M E R+ +K++ E++ R + + + Q ++QE+ +++ E+ +
Sbjct: 707 EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQ--------EEKMW 758
Query: 150 QKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLR 209
++ E M E++R L E +K + + +++E + E E ++ Q+ ++ +R
Sbjct: 759 EQEEKMWEQQR-----LPEQKEKLWEHEKMQEQEKIWEQE--EKMRDQEEKMRGQEEKMR 811
Query: 210 HRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETE 269
+ + Q + + Q+ ++ + + + + K+ E++QG+ + E+E +
Sbjct: 812 GQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMR 871
Query: 270 PVGEESISDAEKV 282
E+ EK+
Sbjct: 872 GQEEKMREQEEKM 884
Score = 35.0 bits (79), Expect = 0.12
Identities = 38/189 (20%), Positives = 93/189 (49%), Gaps = 32/189 (16%)
Query: 83 ELDRLRLERMDRIEKERKHQKE--LELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHK 140
E+ R + E+M E++ + Q+E E E +W E ++ + + +L E+ ++L H+
Sbjct: 727 EMMREQEEKMQEQEEKMQEQEEEMWEQEEKMW--EQEEKMWEQQRLPEQKEKLW---EHE 781
Query: 141 DVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTR 200
+ E+ +++ E M ++E + M+ +E + Q +++R ++ ++ + E + +++
Sbjct: 782 KMQEQEKIWEQEEKMRDQEEK-MRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEK--- 837
Query: 201 LMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEM----GSLRAELGKLRERLQG 256
+ Q + + Q+ ++E +Q +E++M +R + K+RE+
Sbjct: 838 --------------MWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQ--- 880
Query: 257 EHSQNGEEE 265
E G+EE
Sbjct: 881 EEKMRGQEE 889
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 59.3 bits (142), Expect = 6e-09
Identities = 79/326 (24%), Positives = 142/326 (43%), Gaps = 54/326 (16%)
Query: 59 RVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQD 118
R+ ++ L A L +L+ + + + E R++KE K ++ELE ++ G+A D
Sbjct: 1007 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD 1066
Query: 119 LLSQIAQLQEENKQLMTNLSHKD-------VNFSEEEFQKHEGMSE-RERQ-VMKKLKEV 169
QIA LQ + +L L+ K+ +E QK+ + + RE + + L+E
Sbjct: 1067 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED 1126
Query: 170 VDKQ---RDEIRAKDRELG-----LKNE------------DVEALQQQQTRLMK--INHD 207
+D + R++ + R+LG LK E ++ A ++Q+ ++K ++ +
Sbjct: 1127 LDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEE 1186
Query: 208 LR-HRVTVVEAQGK------ALIEQ-------KVELEADLQTKEQEMGSLRAELGKLRER 253
R H V E + K L EQ K L+ + QT E+E L EL L +
Sbjct: 1187 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1246
Query: 254 LQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKV 313
Q + + E + + + + SD E+ +L D + E+ V NE + K
Sbjct: 1247 KQEVEHKKKKLEAQVQEL-QSKCSDGERARAELND--KVHKLQNEVESVTGMLNEAEGKA 1303
Query: 314 FLLQEELAYYKS------EEMEEENR 333
L +++A S E ++EE R
Sbjct: 1304 IKLAKDVASLSSQLQDTQELLQEETR 1329
Score = 50.4 bits (119), Expect = 3e-06
Identities = 88/416 (21%), Positives = 177/416 (42%), Gaps = 46/416 (11%)
Query: 1 MEEERGSA-------LAAESALEKNVAELTVM------DVYDIASLV-GHEFERVIDQHG 46
+EEER S + A+ LE++++ L + + D AS V E + Q
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 47 CEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELE 106
E + + + + LE +++ + ELD+L ++LD R + +K+RK + L
Sbjct: 1401 IENLTQQYEEKAAAYDKLEK--TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 107 LVEDVWRGEAQDLLSQIAQLQE-ENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKK 165
+++ A + A+ +E E K L + ++ ++EE ++ M + E + +
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518
Query: 166 LKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTV----------- 214
K+ V K E+ R L + E+++ ++ ++ D + R+ V
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
Query: 215 -VEAQGKALIEQKVELEADLQTKEQEM---GSLRAELGKLRERLQGEHSQNGEEEPETEP 270
++A+ + E++ +L+ L E E+ RA +++L+G+ +
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
Query: 271 VGEESISDAEKVAMDLKDPNRPRFTLQELRDVLH---ERNELKSK-----VFLLQEELA- 321
EE+I K+ +KD R + RD + + NE K+K + LQE+LA
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
Query: 322 ---YYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFFSRDKKRLANTQRNV 374
K ++E+E + R + Q E +RL + ++ ++ L Q N+
Sbjct: 1699 AERARKQADLEKEELAEELASSLSGRNALQDEK--RRLEARIAQLEEELEEEQGNM 1752
Score = 47.0 bits (110), Expect = 3e-05
Identities = 73/329 (22%), Positives = 144/329 (43%), Gaps = 39/329 (11%)
Query: 1 MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRV 60
+E+ER A +A +K +L +++ +++ G E EAI +L ++
Sbjct: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE----------EAIKQLRKLQAQM 1654
Query: 61 L----EILEVLVSRHHV---APELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWR 113
E+ + SR + A E ++ L+ ++ + + + +K+ +L ++
Sbjct: 1655 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1714
Query: 114 GEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQ 173
E LS LQ+E ++L ++ + EEE E MS+R R+ ++ +++ ++
Sbjct: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE- 1772
Query: 174 RDEIRAKDRELGLKNEDV-EALQQQQTRLMKINHDL------RHRVTVVEAQGK-ALIEQ 225
A +R KNE + L++Q L H++ + + T+ + K A +E+
Sbjct: 1773 ----LATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1828
Query: 226 KVELEADLQTKEQEMGSLRAELGKLRE-RLQGEHSQN-GEEEPETEPVGEESISDAEKVA 283
+VE EA + K+ SL+ + KL+E LQ E + E+ E G + ++
Sbjct: 1829 QVEQEA--REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
Query: 284 MDLKDP----NRPRFTLQELRDVLHERNE 308
+ ++ N R LQ D E NE
Sbjct: 1887 EEAEEESQRINANRRKLQRELDEATESNE 1915
Score = 46.2 bits (108), Expect = 5e-05
Identities = 61/307 (19%), Positives = 123/307 (40%), Gaps = 29/307 (9%)
Query: 48 EAIARLMPKVVRVLEILEVLVSR----HHVAPELDELRLELDRLRLERMDRIEKERKHQK 103
E RL K + EIL + +R +L R ++ + L+ +++E+E ++
Sbjct: 908 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
Query: 104 ELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVM 163
+L+L + + + L +I + ++N +L K+ EE E +
Sbjct: 968 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLS-----KERKLLEERISDLTTNLAEEEEKA 1022
Query: 164 KKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALI 223
K L ++ +K I + L + + + L++ + +L D ++ ++AQ L
Sbjct: 1023 KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1082
Query: 224 EQKVELEADLQ--------------TKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETE 269
Q + E +LQ +++ L + L+E L E + + E +
Sbjct: 1083 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKR 1142
Query: 270 PVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEME 329
+GEE E + +L+D T QELR + + K L EE ++++ E
Sbjct: 1143 DLGEE----LEALKTELEDTLDSTATQQELRAKREQEVTVLKKA--LDEETRSHEAQVQE 1196
Query: 330 EENRIPQ 336
+ Q
Sbjct: 1197 MRQKHAQ 1203
Score = 43.5 bits (101), Expect = 3e-04
Identities = 46/187 (24%), Positives = 89/187 (47%), Gaps = 17/187 (9%)
Query: 150 QKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQ---QTRLMKINH 206
++ E M +E + ++K KE K +E++ +++ E+ LQ+Q +T L
Sbjct: 849 RQEEEMQAKEDE-LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 907
Query: 207 DLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEP 266
++R R+ A+ + L E E+EA L+ +E L+AE K+ +++ Q EEE
Sbjct: 908 EMRVRLA---AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 964
Query: 267 ETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSE 326
+ + E ++ AE L+D E+ + + N+L + LL+E ++ +
Sbjct: 965 ARQKLQLEKVT-AEAKIKKLED---------EILVMDDQNNKLSKERKLLEERISDLTTN 1014
Query: 327 EMEEENR 333
EEE +
Sbjct: 1015 LAEEEEK 1021
Score = 42.4 bits (98), Expect = 8e-04
Identities = 60/278 (21%), Positives = 118/278 (42%), Gaps = 27/278 (9%)
Query: 76 ELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMT 135
+L+E R L E M+ + +H L + + + QD S + L+E K+
Sbjct: 1340 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1399
Query: 136 NLSHKDVNFSEE--EFQKHEGMSERERQVMKKLKEVVDKQR-------------DEIRAK 180
+ + + E+ + K E R +Q + L +D QR D++ A+
Sbjct: 1400 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1459
Query: 181 DRELGLKNED----VEA-LQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQT 235
++ + K D EA ++++T+ + + L + E + K E+E DL +
Sbjct: 1460 EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME-DLVS 1518
Query: 236 KEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFT 295
+ ++G EL K + L+ +Q E + + E + E+ + E + L + N
Sbjct: 1519 SKDDVGKNVHELEKSKRALE---TQMEEMKTQLEEL-EDELQATEDAKLRL-EVNMQALK 1573
Query: 296 LQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENR 333
Q RD+ + + K LQ +L Y++ E+E+E +
Sbjct: 1574 GQFERDLQARDEQNEEKRRQLQRQLHEYET-ELEDERK 1610
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 59.3 bits (142), Expect = 6e-09
Identities = 79/326 (24%), Positives = 142/326 (43%), Gaps = 54/326 (16%)
Query: 59 RVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQD 118
R+ ++ L A L +L+ + + + E R++KE K ++ELE ++ G+A D
Sbjct: 1014 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD 1073
Query: 119 LLSQIAQLQEENKQLMTNLSHKD-------VNFSEEEFQKHEGMSE-RERQ-VMKKLKEV 169
QIA LQ + +L L+ K+ +E QK+ + + RE + + L+E
Sbjct: 1074 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED 1133
Query: 170 VDKQ---RDEIRAKDRELG-----LKNE------------DVEALQQQQTRLMK--INHD 207
+D + R++ + R+LG LK E ++ A ++Q+ ++K ++ +
Sbjct: 1134 LDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEE 1193
Query: 208 LR-HRVTVVEAQGK------ALIEQ-------KVELEADLQTKEQEMGSLRAELGKLRER 253
R H V E + K L EQ K L+ + QT E+E L EL L +
Sbjct: 1194 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1253
Query: 254 LQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKV 313
Q + + E + + + + SD E+ +L D + E+ V NE + K
Sbjct: 1254 KQEVEHKKKKLEAQVQEL-QSKCSDGERARAELND--KVHKLQNEVESVTGMLNEAEGKA 1310
Query: 314 FLLQEELAYYKS------EEMEEENR 333
L +++A S E ++EE R
Sbjct: 1311 IKLAKDVASLSSQLQDTQELLQEETR 1336
Score = 50.4 bits (119), Expect = 3e-06
Identities = 88/416 (21%), Positives = 177/416 (42%), Gaps = 46/416 (11%)
Query: 1 MEEERGSA-------LAAESALEKNVAELTVM------DVYDIASLV-GHEFERVIDQHG 46
+EEER S + A+ LE++++ L + + D AS V E + Q
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 47 CEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELE 106
E + + + + LE +++ + ELD+L ++LD R + +K+RK + L
Sbjct: 1408 IENLTQQYEEKAAAYDKLEK--TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 107 LVEDVWRGEAQDLLSQIAQLQE-ENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKK 165
+++ A + A+ +E E K L + ++ ++EE ++ M + E + +
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525
Query: 166 LKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTV----------- 214
K+ V K E+ R L + E+++ ++ ++ D + R+ V
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585
Query: 215 -VEAQGKALIEQKVELEADLQTKEQEM---GSLRAELGKLRERLQGEHSQNGEEEPETEP 270
++A+ + E++ +L+ L E E+ RA +++L+G+ +
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645
Query: 271 VGEESISDAEKVAMDLKDPNRPRFTLQELRDVLH---ERNELKSK-----VFLLQEELA- 321
EE+I K+ +KD R + RD + + NE K+K + LQE+LA
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705
Query: 322 ---YYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFFSRDKKRLANTQRNV 374
K ++E+E + R + Q E +RL + ++ ++ L Q N+
Sbjct: 1706 AERARKQADLEKEELAEELASSLSGRNALQDEK--RRLEARIAQLEEELEEEQGNM 1759
Score = 47.0 bits (110), Expect = 3e-05
Identities = 73/329 (22%), Positives = 144/329 (43%), Gaps = 39/329 (11%)
Query: 1 MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRV 60
+E+ER A +A +K +L +++ +++ G E EAI +L ++
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE----------EAIKQLRKLQAQM 1661
Query: 61 L----EILEVLVSRHHV---APELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWR 113
E+ + SR + A E ++ L+ ++ + + + +K+ +L ++
Sbjct: 1662 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1721
Query: 114 GEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQ 173
E LS LQ+E ++L ++ + EEE E MS+R R+ ++ +++ ++
Sbjct: 1722 EELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE- 1779
Query: 174 RDEIRAKDRELGLKNEDV-EALQQQQTRLMKINHDL------RHRVTVVEAQGK-ALIEQ 225
A +R KNE + L++Q L H++ + + T+ + K A +E+
Sbjct: 1780 ----LATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1835
Query: 226 KVELEADLQTKEQEMGSLRAELGKLRE-RLQGEHSQN-GEEEPETEPVGEESISDAEKVA 283
+VE EA + K+ SL+ + KL+E LQ E + E+ E G + ++
Sbjct: 1836 QVEQEA--REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1893
Query: 284 MDLKDP----NRPRFTLQELRDVLHERNE 308
+ ++ N R LQ D E NE
Sbjct: 1894 EEAEEESQRINANRRKLQRELDEATESNE 1922
Score = 46.2 bits (108), Expect = 5e-05
Identities = 61/307 (19%), Positives = 123/307 (40%), Gaps = 29/307 (9%)
Query: 48 EAIARLMPKVVRVLEILEVLVSR----HHVAPELDELRLELDRLRLERMDRIEKERKHQK 103
E RL K + EIL + +R +L R ++ + L+ +++E+E ++
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974
Query: 104 ELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVM 163
+L+L + + + L +I + ++N +L K+ EE E +
Sbjct: 975 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLS-----KERKLLEERISDLTTNLAEEEEKA 1029
Query: 164 KKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALI 223
K L ++ +K I + L + + + L++ + +L D ++ ++AQ L
Sbjct: 1030 KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1089
Query: 224 EQKVELEADLQ--------------TKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETE 269
Q + E +LQ +++ L + L+E L E + + E +
Sbjct: 1090 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKR 1149
Query: 270 PVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEME 329
+GEE E + +L+D T QELR + + K L EE ++++ E
Sbjct: 1150 DLGEE----LEALKTELEDTLDSTATQQELRAKREQEVTVLKKA--LDEETRSHEAQVQE 1203
Query: 330 EENRIPQ 336
+ Q
Sbjct: 1204 MRQKHAQ 1210
Score = 43.5 bits (101), Expect = 3e-04
Identities = 46/187 (24%), Positives = 89/187 (47%), Gaps = 17/187 (9%)
Query: 150 QKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQ---QTRLMKINH 206
++ E M +E + ++K KE K +E++ +++ E+ LQ+Q +T L
Sbjct: 856 RQEEEMQAKEDE-LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 914
Query: 207 DLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEP 266
++R R+ A+ + L E E+EA L+ +E L+AE K+ +++ Q EEE
Sbjct: 915 EMRVRLA---AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 971
Query: 267 ETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSE 326
+ + E ++ AE L+D E+ + + N+L + LL+E ++ +
Sbjct: 972 ARQKLQLEKVT-AEAKIKKLED---------EILVMDDQNNKLSKERKLLEERISDLTTN 1021
Query: 327 EMEEENR 333
EEE +
Sbjct: 1022 LAEEEEK 1028
Score = 42.4 bits (98), Expect = 8e-04
Identities = 60/278 (21%), Positives = 118/278 (42%), Gaps = 27/278 (9%)
Query: 76 ELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMT 135
+L+E R L E M+ + +H L + + + QD S + L+E K+
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1406
Query: 136 NLSHKDVNFSEE--EFQKHEGMSERERQVMKKLKEVVDKQR-------------DEIRAK 180
+ + + E+ + K E R +Q + L +D QR D++ A+
Sbjct: 1407 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1466
Query: 181 DRELGLKNED----VEA-LQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQT 235
++ + K D EA ++++T+ + + L + E + K E+E DL +
Sbjct: 1467 EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME-DLVS 1525
Query: 236 KEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFT 295
+ ++G EL K + L+ +Q E + + E + E+ + E + L + N
Sbjct: 1526 SKDDVGKNVHELEKSKRALE---TQMEEMKTQLEEL-EDELQATEDAKLRL-EVNMQALK 1580
Query: 296 LQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENR 333
Q RD+ + + K LQ +L Y++ E+E+E +
Sbjct: 1581 GQFERDLQARDEQNEEKRRQLQRQLHEYET-ELEDERK 1617
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 59.3 bits (142), Expect = 6e-09
Identities = 79/326 (24%), Positives = 142/326 (43%), Gaps = 54/326 (16%)
Query: 59 RVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQD 118
R+ ++ L A L +L+ + + + E R++KE K ++ELE ++ G+A D
Sbjct: 1014 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD 1073
Query: 119 LLSQIAQLQEENKQLMTNLSHKD-------VNFSEEEFQKHEGMSE-RERQ-VMKKLKEV 169
QIA LQ + +L L+ K+ +E QK+ + + RE + + L+E
Sbjct: 1074 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED 1133
Query: 170 VDKQ---RDEIRAKDRELG-----LKNE------------DVEALQQQQTRLMK--INHD 207
+D + R++ + R+LG LK E ++ A ++Q+ ++K ++ +
Sbjct: 1134 LDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEE 1193
Query: 208 LR-HRVTVVEAQGK------ALIEQ-------KVELEADLQTKEQEMGSLRAELGKLRER 253
R H V E + K L EQ K L+ + QT E+E L EL L +
Sbjct: 1194 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1253
Query: 254 LQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKV 313
Q + + E + + + + SD E+ +L D + E+ V NE + K
Sbjct: 1254 KQEVEHKKKKLEAQVQEL-QSKCSDGERARAELND--KVHKLQNEVESVTGMLNEAEGKA 1310
Query: 314 FLLQEELAYYKS------EEMEEENR 333
L +++A S E ++EE R
Sbjct: 1311 IKLAKDVASLSSQLQDTQELLQEETR 1336
Score = 50.4 bits (119), Expect = 3e-06
Identities = 88/416 (21%), Positives = 177/416 (42%), Gaps = 46/416 (11%)
Query: 1 MEEERGSA-------LAAESALEKNVAELTVM------DVYDIASLV-GHEFERVIDQHG 46
+EEER S + A+ LE++++ L + + D AS V E + Q
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 47 CEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELE 106
E + + + + LE +++ + ELD+L ++LD R + +K+RK + L
Sbjct: 1408 IENLTQQYEEKAAAYDKLEK--TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 107 LVEDVWRGEAQDLLSQIAQLQE-ENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKK 165
+++ A + A+ +E E K L + ++ ++EE ++ M + E + +
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525
Query: 166 LKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTV----------- 214
K+ V K E+ R L + E+++ ++ ++ D + R+ V
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585
Query: 215 -VEAQGKALIEQKVELEADLQTKEQEM---GSLRAELGKLRERLQGEHSQNGEEEPETEP 270
++A+ + E++ +L+ L E E+ RA +++L+G+ +
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645
Query: 271 VGEESISDAEKVAMDLKDPNRPRFTLQELRDVLH---ERNELKSK-----VFLLQEELA- 321
EE+I K+ +KD R + RD + + NE K+K + LQE+LA
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705
Query: 322 ---YYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFFSRDKKRLANTQRNV 374
K ++E+E + R + Q E +RL + ++ ++ L Q N+
Sbjct: 1706 AERARKQADLEKEELAEELASSLSGRNALQDEK--RRLEARIAQLEEELEEEQGNM 1759
Score = 47.8 bits (112), Expect = 2e-05
Identities = 79/361 (21%), Positives = 155/361 (42%), Gaps = 54/361 (14%)
Query: 1 MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRV 60
+E+ER A +A +K +L +++ +++ G E EAI +L ++
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE----------EAIKQLRKLQAQM 1661
Query: 61 L----EILEVLVSRHHV---APELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWR 113
E+ + SR + A E ++ L+ ++ + + + +K+ +L ++
Sbjct: 1662 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1721
Query: 114 GEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQ 173
E LS LQ+E ++L ++ + EEE E MS+R R+ ++ +++ ++
Sbjct: 1722 EELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE- 1779
Query: 174 RDEIRAKDRELGLKNEDV-EALQQQQTRLMKINHDL------RHRVTVVEAQGK-ALIEQ 225
A +R KNE + L++Q L H++ + + T+ + K A +E+
Sbjct: 1780 ----LATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1835
Query: 226 KVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMD 285
+VE EA + K+ SL+ + KL+E L + + + E+ AEK
Sbjct: 1836 QVEQEA--REKQAATKSLKQKDKKLKEILL--------QVEDERKMAEQYKEQAEKGNAR 1885
Query: 286 LKDPNRPRFTLQELRDVLHERNELKSKVFLLQEEL--AYYKSEEMEEE-----NRIPQPP 338
+K R +L + E + + LQ EL A +E M E +++ PP
Sbjct: 1886 VKQLKR------QLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPP 1939
Query: 339 P 339
P
Sbjct: 1940 P 1940
Score = 46.2 bits (108), Expect = 5e-05
Identities = 61/307 (19%), Positives = 123/307 (40%), Gaps = 29/307 (9%)
Query: 48 EAIARLMPKVVRVLEILEVLVSR----HHVAPELDELRLELDRLRLERMDRIEKERKHQK 103
E RL K + EIL + +R +L R ++ + L+ +++E+E ++
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974
Query: 104 ELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVM 163
+L+L + + + L +I + ++N +L K+ EE E +
Sbjct: 975 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLS-----KERKLLEERISDLTTNLAEEEEKA 1029
Query: 164 KKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALI 223
K L ++ +K I + L + + + L++ + +L D ++ ++AQ L
Sbjct: 1030 KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1089
Query: 224 EQKVELEADLQ--------------TKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETE 269
Q + E +LQ +++ L + L+E L E + + E +
Sbjct: 1090 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKR 1149
Query: 270 PVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEME 329
+GEE E + +L+D T QELR + + K L EE ++++ E
Sbjct: 1150 DLGEE----LEALKTELEDTLDSTATQQELRAKREQEVTVLKKA--LDEETRSHEAQVQE 1203
Query: 330 EENRIPQ 336
+ Q
Sbjct: 1204 MRQKHAQ 1210
Score = 43.5 bits (101), Expect = 3e-04
Identities = 46/187 (24%), Positives = 89/187 (47%), Gaps = 17/187 (9%)
Query: 150 QKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQ---QTRLMKINH 206
++ E M +E + ++K KE K +E++ +++ E+ LQ+Q +T L
Sbjct: 856 RQEEEMQAKEDE-LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 914
Query: 207 DLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEP 266
++R R+ A+ + L E E+EA L+ +E L+AE K+ +++ Q EEE
Sbjct: 915 EMRVRLA---AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 971
Query: 267 ETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSE 326
+ + E ++ AE L+D E+ + + N+L + LL+E ++ +
Sbjct: 972 ARQKLQLEKVT-AEAKIKKLED---------EILVMDDQNNKLSKERKLLEERISDLTTN 1021
Query: 327 EMEEENR 333
EEE +
Sbjct: 1022 LAEEEEK 1028
Score = 42.4 bits (98), Expect = 8e-04
Identities = 60/278 (21%), Positives = 118/278 (42%), Gaps = 27/278 (9%)
Query: 76 ELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMT 135
+L+E R L E M+ + +H L + + + QD S + L+E K+
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1406
Query: 136 NLSHKDVNFSEE--EFQKHEGMSERERQVMKKLKEVVDKQR-------------DEIRAK 180
+ + + E+ + K E R +Q + L +D QR D++ A+
Sbjct: 1407 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1466
Query: 181 DRELGLKNED----VEA-LQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQT 235
++ + K D EA ++++T+ + + L + E + K E+E DL +
Sbjct: 1467 EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME-DLVS 1525
Query: 236 KEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFT 295
+ ++G EL K + L+ +Q E + + E + E+ + E + L + N
Sbjct: 1526 SKDDVGKNVHELEKSKRALE---TQMEEMKTQLEEL-EDELQATEDAKLRL-EVNMQALK 1580
Query: 296 LQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENR 333
Q RD+ + + K LQ +L Y++ E+E+E +
Sbjct: 1581 GQFERDLQARDEQNEEKRRQLQRQLHEYET-ELEDERK 1617
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 59.3 bits (142), Expect = 6e-09
Identities = 79/326 (24%), Positives = 142/326 (43%), Gaps = 54/326 (16%)
Query: 59 RVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQD 118
R+ ++ L A L +L+ + + + E R++KE K ++ELE ++ G+A D
Sbjct: 1007 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD 1066
Query: 119 LLSQIAQLQEENKQLMTNLSHKD-------VNFSEEEFQKHEGMSE-RERQ-VMKKLKEV 169
QIA LQ + +L L+ K+ +E QK+ + + RE + + L+E
Sbjct: 1067 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED 1126
Query: 170 VDKQ---RDEIRAKDRELG-----LKNE------------DVEALQQQQTRLMK--INHD 207
+D + R++ + R+LG LK E ++ A ++Q+ ++K ++ +
Sbjct: 1127 LDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEE 1186
Query: 208 LR-HRVTVVEAQGK------ALIEQ-------KVELEADLQTKEQEMGSLRAELGKLRER 253
R H V E + K L EQ K L+ + QT E+E L EL L +
Sbjct: 1187 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1246
Query: 254 LQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKV 313
Q + + E + + + + SD E+ +L D + E+ V NE + K
Sbjct: 1247 KQEVEHKKKKLEAQVQEL-QSKCSDGERARAELND--KVHKLQNEVESVTGMLNEAEGKA 1303
Query: 314 FLLQEELAYYKS------EEMEEENR 333
L +++A S E ++EE R
Sbjct: 1304 IKLAKDVASLSSQLQDTQELLQEETR 1329
Score = 50.4 bits (119), Expect = 3e-06
Identities = 88/416 (21%), Positives = 177/416 (42%), Gaps = 46/416 (11%)
Query: 1 MEEERGSA-------LAAESALEKNVAELTVM------DVYDIASLV-GHEFERVIDQHG 46
+EEER S + A+ LE++++ L + + D AS V E + Q
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 47 CEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELE 106
E + + + + LE +++ + ELD+L ++LD R + +K+RK + L
Sbjct: 1401 IENLTQQYEEKAAAYDKLEK--TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 107 LVEDVWRGEAQDLLSQIAQLQE-ENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKK 165
+++ A + A+ +E E K L + ++ ++EE ++ M + E + +
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518
Query: 166 LKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTV----------- 214
K+ V K E+ R L + E+++ ++ ++ D + R+ V
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
Query: 215 -VEAQGKALIEQKVELEADLQTKEQEM---GSLRAELGKLRERLQGEHSQNGEEEPETEP 270
++A+ + E++ +L+ L E E+ RA +++L+G+ +
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
Query: 271 VGEESISDAEKVAMDLKDPNRPRFTLQELRDVLH---ERNELKSK-----VFLLQEELA- 321
EE+I K+ +KD R + RD + + NE K+K + LQE+LA
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
Query: 322 ---YYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFFSRDKKRLANTQRNV 374
K ++E+E + R + Q E +RL + ++ ++ L Q N+
Sbjct: 1699 AERARKQADLEKEELAEELASSLSGRNALQDEK--RRLEARIAQLEEELEEEQGNM 1752
Score = 47.8 bits (112), Expect = 2e-05
Identities = 79/361 (21%), Positives = 155/361 (42%), Gaps = 54/361 (14%)
Query: 1 MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRV 60
+E+ER A +A +K +L +++ +++ G E EAI +L ++
Sbjct: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE----------EAIKQLRKLQAQM 1654
Query: 61 L----EILEVLVSRHHV---APELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWR 113
E+ + SR + A E ++ L+ ++ + + + +K+ +L ++
Sbjct: 1655 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1714
Query: 114 GEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQ 173
E LS LQ+E ++L ++ + EEE E MS+R R+ ++ +++ ++
Sbjct: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE- 1772
Query: 174 RDEIRAKDRELGLKNEDV-EALQQQQTRLMKINHDL------RHRVTVVEAQGK-ALIEQ 225
A +R KNE + L++Q L H++ + + T+ + K A +E+
Sbjct: 1773 ----LATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1828
Query: 226 KVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMD 285
+VE EA + K+ SL+ + KL+E L + + + E+ AEK
Sbjct: 1829 QVEQEA--REKQAATKSLKQKDKKLKEILL--------QVEDERKMAEQYKEQAEKGNAR 1878
Query: 286 LKDPNRPRFTLQELRDVLHERNELKSKVFLLQEEL--AYYKSEEMEEE-----NRIPQPP 338
+K R +L + E + + LQ EL A +E M E +++ PP
Sbjct: 1879 VKQLKR------QLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPP 1932
Query: 339 P 339
P
Sbjct: 1933 P 1933
Score = 46.2 bits (108), Expect = 5e-05
Identities = 61/307 (19%), Positives = 123/307 (40%), Gaps = 29/307 (9%)
Query: 48 EAIARLMPKVVRVLEILEVLVSR----HHVAPELDELRLELDRLRLERMDRIEKERKHQK 103
E RL K + EIL + +R +L R ++ + L+ +++E+E ++
Sbjct: 908 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
Query: 104 ELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVM 163
+L+L + + + L +I + ++N +L K+ EE E +
Sbjct: 968 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLS-----KERKLLEERISDLTTNLAEEEEKA 1022
Query: 164 KKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALI 223
K L ++ +K I + L + + + L++ + +L D ++ ++AQ L
Sbjct: 1023 KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1082
Query: 224 EQKVELEADLQ--------------TKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETE 269
Q + E +LQ +++ L + L+E L E + + E +
Sbjct: 1083 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKR 1142
Query: 270 PVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEME 329
+GEE E + +L+D T QELR + + K L EE ++++ E
Sbjct: 1143 DLGEE----LEALKTELEDTLDSTATQQELRAKREQEVTVLKKA--LDEETRSHEAQVQE 1196
Query: 330 EENRIPQ 336
+ Q
Sbjct: 1197 MRQKHAQ 1203
Score = 43.5 bits (101), Expect = 3e-04
Identities = 46/187 (24%), Positives = 89/187 (47%), Gaps = 17/187 (9%)
Query: 150 QKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQ---QTRLMKINH 206
++ E M +E + ++K KE K +E++ +++ E+ LQ+Q +T L
Sbjct: 849 RQEEEMQAKEDE-LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 907
Query: 207 DLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEP 266
++R R+ A+ + L E E+EA L+ +E L+AE K+ +++ Q EEE
Sbjct: 908 EMRVRLA---AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 964
Query: 267 ETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSE 326
+ + E ++ AE L+D E+ + + N+L + LL+E ++ +
Sbjct: 965 ARQKLQLEKVT-AEAKIKKLED---------EILVMDDQNNKLSKERKLLEERISDLTTN 1014
Query: 327 EMEEENR 333
EEE +
Sbjct: 1015 LAEEEEK 1021
Score = 42.4 bits (98), Expect = 8e-04
Identities = 60/278 (21%), Positives = 118/278 (42%), Gaps = 27/278 (9%)
Query: 76 ELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMT 135
+L+E R L E M+ + +H L + + + QD S + L+E K+
Sbjct: 1340 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1399
Query: 136 NLSHKDVNFSEE--EFQKHEGMSERERQVMKKLKEVVDKQR-------------DEIRAK 180
+ + + E+ + K E R +Q + L +D QR D++ A+
Sbjct: 1400 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1459
Query: 181 DRELGLKNED----VEA-LQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQT 235
++ + K D EA ++++T+ + + L + E + K E+E DL +
Sbjct: 1460 EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME-DLVS 1518
Query: 236 KEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFT 295
+ ++G EL K + L+ +Q E + + E + E+ + E + L + N
Sbjct: 1519 SKDDVGKNVHELEKSKRALE---TQMEEMKTQLEEL-EDELQATEDAKLRL-EVNMQALK 1573
Query: 296 LQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENR 333
Q RD+ + + K LQ +L Y++ E+E+E +
Sbjct: 1574 GQFERDLQARDEQNEEKRRQLQRQLHEYET-ELEDERK 1610
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 59.3 bits (142), Expect = 6e-09
Identities = 79/343 (23%), Positives = 155/343 (45%), Gaps = 42/343 (12%)
Query: 11 AESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILEVLVSR 70
A+ EKN+ E ++ ++ L+ EF++ D + A + E + L+S+
Sbjct: 703 AQEIYEKNLDE-KAKEISNLNQLI-EEFKKNADNNSSAFTA--------LSEERDQLLSQ 752
Query: 71 HHVAPELDELRLELDRLRL-----ERMDRIEKERKHQKELELVEDVW----RGEAQDLLS 121
+ ELR ++ +L + ER R++ E + + L E + +++D+
Sbjct: 753 VKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKI 812
Query: 122 QIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGM----SERERQVMKKLKEV---VDKQR 174
++ Q + ++ QL + + + + Q E +ER R + K++E+ + ++
Sbjct: 813 EVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE 872
Query: 175 DEIRAKDRELGLKNEDVEALQQ----QQTRLMKINHDLRHRVTVVEAQGKALIEQKVELE 230
EI D+ L K DVE LQQ + ++ +I+ + ++ L E+K L
Sbjct: 873 LEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMV-------QLNEEKFSLG 925
Query: 231 ADLQTKEQEMGSL-RAELGKLRERLQGEHSQNGEEE--PETEPVGEESISDAEKVAMDLK 287
+++T ++++ L RAE K + + +G ++ E P G+ S + + LK
Sbjct: 926 VEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLK 985
Query: 288 DPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEE 330
N R ++L+ L R EL +V L+EELA K E +E
Sbjct: 986 KENEQR--KRKLQAALINRKELLQRVSRLEEELANLKDESKKE 1026
Score = 54.3 bits (129), Expect = 2e-07
Identities = 75/379 (19%), Positives = 147/379 (38%), Gaps = 54/379 (14%)
Query: 51 ARLMPKVVRVLEIL-EVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVE 109
A+L ++++ E L +V+ + +L E++L+ ++ + ++E++ K +E E
Sbjct: 2527 AKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEAN--E 2584
Query: 110 DVWRG------EAQDLLSQIAQLQEENKQLMTNLS-----------HKDVNFSEEEF--- 149
D+ R E QDL +I L+ QL ++ H + EEE
Sbjct: 2585 DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRL 2644
Query: 150 -------QKHEGMSERE-----RQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQ 197
QK E E ++ KK+ E+ DK + E++ + G+ + E +++
Sbjct: 2645 SALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEER 2704
Query: 198 QTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRER---- 253
L + ++ ++ +V + K L Q + + + EL +L+ +
Sbjct: 2705 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDAS 2764
Query: 254 ------LQGEHSQNGEEEP-------ETEPVGEESISDAEKVAMDLKDPNRPRFTLQ-EL 299
L+ + N E + E S+S EK+ L + L +L
Sbjct: 2765 LKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQL 2824
Query: 300 RDVLHERNELKSKVFLLQEELAYYKSE-EMEEENRIPQPPPIAHPRTSPQPESGIKRLFS 358
D ++ + LQ E + +E E ++ + A P TSP +K+ S
Sbjct: 2825 EDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMS 2884
Query: 359 FFSRDKKRLANTQRNVHIQ 377
D+ RL +N+ Q
Sbjct: 2885 SLQNDRDRLLKELKNLQQQ 2903
Score = 52.4 bits (124), Expect = 7e-07
Identities = 63/281 (22%), Positives = 130/281 (46%), Gaps = 33/281 (11%)
Query: 69 SRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQE 128
S H PEL+E L L++ EKE+ QK+L+ + + + L+E
Sbjct: 1154 SSEHWKPELEEKILALEK---------EKEQL-QKKLQEALTSRKAILKKAQEKERHLRE 1203
Query: 129 ENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQ---RDEIRAKDRELG 185
E KQ + + F E+ +++E + ++ RQ+ +++E +D + D+ + G
Sbjct: 1204 ELKQQKDDYNRLQEQFDEQS-KENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPG 1262
Query: 186 LKNEDVEALQQQQTR-LMKIN------------HDLRHRVTV--VEAQGKALIEQKVELE 230
L+ +A +Q T+ +++ N L+ +V ++AQ K + +KVELE
Sbjct: 1263 LEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELE 1322
Query: 231 ADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPN 290
+ + E+ E+ +L+E++ ++ G E + V E+ AE + L+
Sbjct: 1323 LKVSSTTSELTKKSEEVFQLQEQI----NKQGLEIESLKTVSHEAEVHAESLQQKLESSQ 1378
Query: 291 RPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEE 331
L+ LR++ + +EL+ + +E+++Y + E+E
Sbjct: 1379 LQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKE 1419
Score = 50.8 bits (120), Expect = 2e-06
Identities = 77/321 (23%), Positives = 134/321 (41%), Gaps = 60/321 (18%)
Query: 96 EKERKHQKELELVEDVWRGEAQ--DLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHE 153
+K R Q++LE E+ G AQ DLL Q E+ Q+++ + + E E
Sbjct: 252 QKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILS----QQLQQMEAEHNTLR 307
Query: 154 GMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKN--EDVEALQQQQTRLMKINHDLRHR 211
E ER+ K L E + E+ +R+L N E++ L +Q + + +L R
Sbjct: 308 NTVETEREESKILLEKM-----ELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESR 362
Query: 212 VTVVEAQGKALIEQKVELEADLQTKEQEMGS----LRAELGKLRE--------------R 253
+ +E + KA +E+K LQ QE+ S L+ + KL + +
Sbjct: 363 YSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQ 422
Query: 254 LQGEHSQNGEEEPE-------------------------TEPVGEESISDAEKVAMDLKD 288
L+ + Q +E + T+ V EE+I+ +K ++L++
Sbjct: 423 LEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELEN 482
Query: 289 PNRPRFTLQ-ELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSP 347
EL ++ E +L S++ LL+ A ++ E + E IA+ R+S
Sbjct: 483 EKGALLLSSIELEELKAENEKLSSQITLLE---AQNRTGEADREVSEISIVDIANKRSSS 539
Query: 348 QPESGIKRLFSFFSRDKKRLA 368
ESG L + FS+ K L+
Sbjct: 540 AEESGQDVLENTFSQKHKELS 560
Score = 47.8 bits (112), Expect = 2e-05
Identities = 54/227 (23%), Positives = 97/227 (42%), Gaps = 27/227 (11%)
Query: 67 LVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQL 126
L+SR E L+ EL R IE+ K ++E E +L ++A L
Sbjct: 1489 LISRKEALKENKSLQEELSLAR----GTIERLTKSLADVESQVSAQNKEKDTVLGRLALL 1544
Query: 127 QEENKQLMTN-----LSHKDVNFSEEEFQ-KHEGMSERERQVMKKLKEVVDK---QRDEI 177
QEE +L+T L ++ ++ S E + EG++E + +++K+++ + + E
Sbjct: 1545 QEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEW 1604
Query: 178 RAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALI-------EQKVELE 230
+ K +EL ++ E L Q + ++H V V + + L K E E
Sbjct: 1605 QEKHKEL---QKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETE 1661
Query: 231 ADLQTKEQEMGSLRAELGKLRERLQGE----HSQNGEEEPETEPVGE 273
LQ EQEM ++ ++ K + Q + +N E P G+
Sbjct: 1662 KQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGD 1708
Score = 46.6 bits (109), Expect = 4e-05
Identities = 59/307 (19%), Positives = 128/307 (41%), Gaps = 30/307 (9%)
Query: 76 ELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLS----QIAQLQEENK 131
+ +E L+ + E++D + +E+ H +E GE Q L+ ++ QLQE
Sbjct: 2129 QAEEKHLKEKKNMQEKLDALRREKVHLEETI-------GEIQVTLNKKDKEVQQLQENLD 2181
Query: 132 QLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDV 191
+T L+ + S + + + E ++ +K + + + +EIR K+ + + +
Sbjct: 2182 STVTQLAAFTKSMSSLQDDRDRVIDEAKKWE-RKFSDAIQSKEEEIRLKEDNCSVLKDQL 2240
Query: 192 EA----LQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKV---------ELEADLQTKEQ 238
+++ + + ++ HD ++ +AQ + ++QKV EL + L+
Sbjct: 2241 RQMSIHMEELKINISRLEHD--KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRH 2298
Query: 239 EMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQE 298
S + EL KL L+ Q + E E+ + + D +F+ ++
Sbjct: 2299 LYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQ 2358
Query: 299 LRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFS 358
L L EL S+ L EE+ + + + + + +A Q + IK L +
Sbjct: 2359 LETDLQASRELTSR---LHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELEN 2415
Query: 359 FFSRDKK 365
S++++
Sbjct: 2416 LLSQEEE 2422
Score = 42.0 bits (97), Expect = 0.001
Identities = 66/305 (21%), Positives = 129/305 (42%), Gaps = 67/305 (21%)
Query: 77 LDELRLELDRLRLERMDRIEKERKHQKELELVE---DVWRGEAQDLLSQ----------- 122
++EL++ + RL D+ E K Q E++L + D +GE ++LLSQ
Sbjct: 2247 MEELKINISRLE---HDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSS 2303
Query: 123 ---IAQLQEENKQL---MTNLSHK-------------DVNFSEEEFQKHEGMSERERQVM 163
+A+L+ E K L +T+LS+ + E + Q + E+ +
Sbjct: 2304 QNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDL 2363
Query: 164 KKLKEVVDKQRDEIRAKDRE----LGLKNEDVEA----LQQQQTRLMKINHDL----RHR 211
+ +E+ + +EI K+++ L K E ++ L+QQ + +K +L
Sbjct: 2364 QASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEE 2423
Query: 212 VTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKL----------RERLQGEHSQN 261
V+E + K +++ +L L+T ++E +A+L R+R+ G++ Q
Sbjct: 2424 NIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2483
Query: 262 GEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELA 321
E ++ I +A LK +E+R + ++L S+ L EL
Sbjct: 2484 EERHLSIILEKDQLIQEAAAENNKLK---------EEIRGLRSHMDDLNSENAKLDAELI 2534
Query: 322 YYKSE 326
Y+ +
Sbjct: 2535 QYRED 2539
Score = 40.8 bits (94), Expect = 0.002
Identities = 54/270 (20%), Positives = 114/270 (42%), Gaps = 44/270 (16%)
Query: 72 HVAPELDELRLEL-DRLRLERMDRIEKERKHQK---ELELVEDVWRGEAQDLLSQIAQLQ 127
HV + + + EL +LR ++ E E++ Q+ E+E +++ R A+ +I +L+
Sbjct: 1634 HVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELE 1693
Query: 128 EENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLK 187
EEN +L + + ++ M+ L ++E+ E
Sbjct: 1694 EENDRLRAEV---------------HPAGDTAKECMETLLSSNASMKEELERVKMEYETL 1738
Query: 188 NEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEA----DLQTKEQEMGSL 243
++ ++L ++ L + DL+H++ + + ++ LEA D QT E G+
Sbjct: 1739 SKKFQSLMSEKDSLSEEVQDLKHQI-------EGNVSKQANLEATEKHDNQTNVTEEGT- 1790
Query: 244 RAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVL 303
+ + GE + T P ES+ A+ + ++ + E+ + L
Sbjct: 1791 --------QSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAV---SKDFSSHDEINNYL 1839
Query: 304 HERNELKSKVFLLQEELAYYK--SEEMEEE 331
+ ++LK ++ L+EE K S+ +E E
Sbjct: 1840 QQIDQLKERIAGLEEEKQKNKEFSQTLENE 1869
Score = 40.4 bits (93), Expect = 0.003
Identities = 55/300 (18%), Positives = 130/300 (43%), Gaps = 49/300 (16%)
Query: 66 VLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRG-----EAQDLL 120
++ + ++ E+ +L+ +++ + + +E KH + + E+ + E QD L
Sbjct: 1745 LMSEKDSLSEEVQDLKHQIEG-NVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSL 1803
Query: 121 SQ---------IAQLQEENKQLMTNLSHKDV--NFSEEEFQKHEGMS--ERERQVMKKLK 167
S + + N + + S D N+ ++ Q E ++ E E+Q K+
Sbjct: 1804 SMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFS 1863
Query: 168 EVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKV 227
+ ++ +++ + + ++ K+ +++ LQ++ T++ +N ++ ++ V + E+K
Sbjct: 1864 QTLENEKNTLLS---QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKD 1920
Query: 228 ELE---------------------ADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEP 266
+LE D Q K + + S L K L+ E Q +E+
Sbjct: 1921 DLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKT 1980
Query: 267 ETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSE 326
+ E E EK+ K+P + +EL+++L E+ + +V LQ++ Y+ +
Sbjct: 1981 KVE--SEIRKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQ---EVKQLQKDCIRYQEK 2034
Score = 38.1 bits (87), Expect = 0.014
Identities = 65/338 (19%), Positives = 137/338 (40%), Gaps = 42/338 (12%)
Query: 3 EERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLE 62
E+ + L A L + E M I SL+ + E + AIA L + + ++
Sbjct: 2357 EQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQ-----VAIAELRQQHDKEIK 2411
Query: 63 ILEVLVSRHH----VAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQD 118
LE L+S+ V E ++ ++ +E + I+KE QK +
Sbjct: 2412 ELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQK----------AQLDS 2461
Query: 119 LLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIR 178
+ ++ LQ + +++ + + ++H + + Q++++ +K ++EIR
Sbjct: 2462 FVKSMSSLQNDRDRIVGDYQQLE--------ERHLSIILEKDQLIQEAAAENNKLKEEIR 2513
Query: 179 AKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQ 238
+ N + L + L++ DL +T+ ++Q K L+E +++ +L+ K
Sbjct: 2514 GLRSHMDDLNSENAKLDAE---LIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYA 2570
Query: 239 EMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQE 298
++ E + E L+ + EE+ ++ + E + + + R LQE
Sbjct: 2571 KLEEKLKESEEANEDLRRSFNALQEEK-------QDLSKEIESLKVSISQLTRQVTALQE 2623
Query: 299 LRDVLHERNELKSKVFLLQEELAYYKSE-----EMEEE 331
+ +LK K + A + S E+EEE
Sbjct: 2624 EGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEE 2661
Score = 33.9 bits (76), Expect = 0.27
Identities = 56/277 (20%), Positives = 114/277 (41%), Gaps = 28/277 (10%)
Query: 62 EILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQ----KELELVEDVWRGEAQ 117
++ E L + EL ++ + D ++ + +++ERK K+L+L A+
Sbjct: 49 DVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKL-------HAK 101
Query: 118 DLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEI 177
L+ + + EE K + + SEE+ KH+ S E ++K+K + ++ + I
Sbjct: 102 AKLTSLNKYIEEMKAQGGTVLPTEPQ-SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELI 160
Query: 178 RAKDREL-----------GLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKA---LI 223
+L + E+ ++QQ + L+ +++ +A+ A +
Sbjct: 161 STLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVR 220
Query: 224 EQKVELEADLQTKEQEMGSLRAELGKLRERLQG-EHSQNGEEEPETEPVGEESISDAEKV 282
E+ E ++ E E+ L + E Q Q EE E VG + D +
Sbjct: 221 EKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQ 280
Query: 283 AMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEE 319
+ + R + Q+L+ + E N L++ V +EE
Sbjct: 281 ELTAAE-QRNQILSQQLQQMEAEHNTLRNTVETEREE 316
Score = 32.0 bits (71), Expect = 1.0
Identities = 44/231 (19%), Positives = 101/231 (43%), Gaps = 33/231 (14%)
Query: 114 GEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQ 173
G A +L +++ + ++ + L + S+ EF +ER + +++V +
Sbjct: 7 GLANVVLHELSGDDDTDQNMRAPLDPELHQESDMEFNNTTQEDVQER--LAYAEQLVVEL 64
Query: 174 RDEIRAKDRELGLKNEDVEALQQQQ----TRLMKINHDLRHRVTVV-------EAQGKAL 222
+D IR KD +L K+E ALQ+++ ++ K+ + ++T + +AQG +
Sbjct: 65 KDIIRQKDVQLQQKDE---ALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTV 121
Query: 223 IEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESIS--DAE 280
+ + + E L ++ E+ K++ +LQ + EE IS A+
Sbjct: 122 LPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEK---------------EELISTLQAQ 166
Query: 281 KVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEE 331
+ P + ++E + + E + + LQ +L+ ++E+ ++
Sbjct: 167 LTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQ 217
Score = 31.6 bits (70), Expect = 1.3
Identities = 32/172 (18%), Positives = 79/172 (45%), Gaps = 16/172 (9%)
Query: 127 QEENKQLMTNLSHKDVNF--SEEEFQKHEGMSERE----RQVMKKLKEVVD--------- 171
Q+E ++L + + ++NF ++E ++K+ +E Q++++ K+ D
Sbjct: 683 QDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTAL 742
Query: 172 -KQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELE 230
++RD++ ++ +EL + E ++Q + L + R A L EQ L
Sbjct: 743 SEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLS 802
Query: 231 ADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKV 282
+ ++K+ ++ L+ EL ++ + + + + + + E + AE+V
Sbjct: 803 IEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERV 854
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 58.5 bits (140), Expect = 1e-08
Identities = 61/296 (20%), Positives = 147/296 (49%), Gaps = 27/296 (9%)
Query: 59 RVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEK-ERKHQKELELVEDVWRGEA- 116
R LE ++L+ + + E D L EL + + ++E+ E ++ + E +WR E
Sbjct: 237 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK 296
Query: 117 --------QDLLSQIAQLQEENKQLMTNLSHKDVNFSEEE---FQKHEGMSERERQV--M 163
Q+ +I + +E+ ++ + K+ +E ++K E + E E ++
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 356
Query: 164 KKLKEVVDKQRDEIRAKDRELGLKNEDVEA-LQQQQTRLMKINHDLRHRVTVVEAQGKAL 222
+K++E +K+++E + +++E K ++ EA + +Q+ ++ + +R + +++ Q + +
Sbjct: 357 EKIREQEEKRQEEEKIREQE---KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 223 IEQKVEL---EADLQTKEQEMG----SLRAELGKLRERLQGEHSQNGEEEPETEPVGEES 275
EQ+ ++ E ++Q +E++M +R + K+RE+ + Q + + E +GE+
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 276 ISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEE 331
E+ A + + R +++R+ + E + K+ QEE+ + E+M E+
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI-REQEEMMQEQEEKMWEQ 528
Score = 52.4 bits (124), Expect = 7e-07
Identities = 58/260 (22%), Positives = 114/260 (43%), Gaps = 22/260 (8%)
Query: 76 ELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMT 135
E D L LEL R + + EK K Q++L+LVE S+ +++Q K+L
Sbjct: 189 ERDALSLELYRNTITDEELKEKNAKLQEKLQLVE-----------SEKSEIQLNVKELKR 237
Query: 136 NLSHKDVNFSEEEFQKHEGMSERERQ-VMKKLKEVVDKQRDEIRAKDRELGLKNEDVEAL 194
L + +++ Q +E Q V KL+ V++ R ++ E +
Sbjct: 238 KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI 297
Query: 195 QQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERL 254
Q+++ ++ + +R + + Q + + E+ E ++ +E+ M ++ +L E++
Sbjct: 298 QEREEKIQEQEEKIREQEEKMRRQEEMMWEK----EEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 255 QGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNEL---KS 311
H Q E E + EE I + EK R ++E + + E+ E+ +
Sbjct: 354 ---HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQE 410
Query: 312 KVFLLQEELAYYKSEEMEEE 331
+ QEE + + EEM+E+
Sbjct: 411 EKMGEQEEKMWEQEEEMQEQ 430
Score = 51.6 bits (122), Expect = 1e-06
Identities = 49/231 (21%), Positives = 114/231 (49%), Gaps = 24/231 (10%)
Query: 65 EVLVSRHHVAPELDELRLELDRLRLERMDRIEKE--RKHQKELELVEDVWRGEAQDLLSQ 122
E++ + EL+E E +++R + R E+E R+ +K E +WR E + + Q
Sbjct: 337 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE-EKIREQ 395
Query: 123 IAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDR 182
+++E+ +++M K E+ +++ E M E+E + M++ +E + +Q +IR ++
Sbjct: 396 EEKIREQ-EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEK-MRRQEEKIREQEKKIREQEE 453
Query: 183 ELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGS 242
++ E E +Q+Q+ ++ E +GK + EQ+ +++ + ++
Sbjct: 454 KI---REQEEMMQEQEEKMG-------------EQEGK-MCEQEAKMQEQEEKMRRQEEK 496
Query: 243 LRAELGKLRERLQ--GEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNR 291
+R + K+RE+ + E + +E+ E EE + + E+ + ++ R
Sbjct: 497 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 547
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 58.2 bits (139), Expect = 1e-08
Identities = 70/297 (23%), Positives = 138/297 (46%), Gaps = 39/297 (13%)
Query: 57 VVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKH--QKELELVEDVWRG 114
V R + LE +S V + EL+ ++ M+R +KE+ H + L ++ G
Sbjct: 354 VEREKQDLEKQMSDLRVQLNFSAMASELEEVK-RCMERKDKEKAHLASQVENLTRELENG 412
Query: 115 EAQDL--LSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERER-----QVMKKLK 167
E Q L L ++ ++Q H D+ SE + + ER Q + LK
Sbjct: 413 EKQQLQMLDRLKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAERYLSELQQSEALK 472
Query: 168 EVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDL-RHRVTVVEAQGK--ALIE 224
E +K+R++++ K + E+++Q + + K+ L + TV E GK +++
Sbjct: 473 EEAEKRREDLKLKAQ---------ESIRQWKLKHKKLERALEKQSETVDELTGKNNQILK 523
Query: 225 QKVELEADLQTKEQEMGSLRAELGKL--RERLQGEHSQNGEEEPETEPVGEESISDAEKV 282
+K EL+ L Q++ +LR EL + + LQ EEE ++ EE + D +
Sbjct: 524 EKDELKTQLYAALQQIENLRKELNDVLTKRALQ-------EEELHSK---EEKLRDIKSH 573
Query: 283 AMDLK-DPNRPRFTLQELRDVLHERNELKSKVFL----LQEELAYYKSEEMEEENRI 334
DL+ + T+ L L ++++++S++ + L+EE+A K + +++ ++
Sbjct: 574 QADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKL 630
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/246 (22%), Positives = 112/246 (45%), Gaps = 35/246 (14%)
Query: 120 LSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRA 179
LS+ ++ E K+ + L+ K E QK E +S+R + +++L+ + +R+ +
Sbjct: 186 LSRRSRSDAETKRALEELTEK-----LNEAQKQEVVSDRVERRLQELEREMRTERELVER 240
Query: 180 KDRELGLKNEDV-EALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVEL--------E 230
+ +LGL + + EAL++Q+ + + +++++ E + K +EQ++EL E
Sbjct: 241 RQDQLGLMSLQLQEALKKQEAKADEHEGAIKNKLRQTETE-KNQLEQELELSRRLLNQSE 299
Query: 231 ADLQTKEQEMGSLRAELGKL---RERLQGEHSQNGEEEPETEPVG----------EESIS 277
+T ++ LR +L K R+ LQ + SQ +++ + E
Sbjct: 300 GSRETLLHQVEELRTQLTKAEGDRKGLQHQVSQISKQQSNYQDEQGEDWRFRRGVEREKQ 359
Query: 278 DAEKVAMDLKDPNRPRFTLQELRDVLH-------ERNELKSKVFLLQEELAYYKSEEMEE 330
D EK DL+ EL +V E+ L S+V L EL + ++++
Sbjct: 360 DLEKQMSDLRVQLNFSAMASELEEVKRCMERKDKEKAHLASQVENLTRELENGEKQQLQM 419
Query: 331 ENRIPQ 336
+R+ +
Sbjct: 420 LDRLKE 425
Score = 42.4 bits (98), Expect = 8e-04
Identities = 75/366 (20%), Positives = 147/366 (40%), Gaps = 88/366 (24%)
Query: 49 AIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELD---RLRLERMDRI---------- 95
A+A + +V R +E + + H+A +++ L EL+ + +L+ +DR+
Sbjct: 376 AMASELEEVKRCMERKDK--EKAHLASQVENLTRELENGEKQQLQMLDRLKEIQNHFDTC 433
Query: 96 EKERKHQKELELVEDVWRGE-----AQDLLSQIAQ---LQEENKQLMTNLSHKDVNFSEE 147
E ERKH +L++ E E A+ LS++ Q L+EE ++ +L K +
Sbjct: 434 EAERKHA-DLQISELTRHAEDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQESIRQ 492
Query: 148 EFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKIN-- 205
KH+ + + + + E+ K ++ KD LK + ALQQ + ++N
Sbjct: 493 WKLKHKKLERALEKQSETVDELTGKNNQILKEKDE---LKTQLYAALQQIENLRKELNDV 549
Query: 206 ------------------HDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAEL 247
D++ +E + K ++ LE++L+ + + ++ E
Sbjct: 550 LTKRALQEEELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEK 609
Query: 248 GKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDL-----KDPNRPRFTLQELRDV 302
L E + +++ + + +ESI D + DL ++ + L++L D+
Sbjct: 610 AHLEEEIAELKKSQAQDKAKLLEM-QESIKDLSAIRADLANKLAEEERAKKAVLKDLSDL 668
Query: 303 -----------------------LHERNELKSKVFLLQ-----------EELAYYKSEEM 328
+H+R ELK LQ E + ++K E+
Sbjct: 669 TAQAKSRDEETATIITQLKLERDVHQR-ELKDLTSSLQSVKTKHEQNIQELMKHFKKEKS 727
Query: 329 EEENRI 334
E EN I
Sbjct: 728 EAENHI 733
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 57.8 bits (138), Expect = 2e-08
Identities = 56/219 (25%), Positives = 110/219 (50%), Gaps = 33/219 (15%)
Query: 52 RLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVED- 110
+L ++VR+ + L +L H EL+ L+ E D+ +R EK ++ Q++LEL +
Sbjct: 1941 KLGKEIVRLQKDLRMLRKEHQ--QELEILKKEYDQ------EREEKIKQEQEDLELKHNS 1992
Query: 111 VWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKL---- 166
+ ++ +Q+AQ ++E + + +K E + H+ E Q++KK+
Sbjct: 1993 TLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQ---EETNQLLKKIAEKD 2049
Query: 167 ----------KEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVE 216
+E++D + +E+ AK R+L + E+++ QQ +L + + VT++E
Sbjct: 2050 DDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQ--KLEQEENPGNDNVTIME 2107
Query: 217 AQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQ 255
Q + + QK L +D + KEQE R ++ L +RL+
Sbjct: 2108 LQTQ--LAQKTTLISDSKLKEQE---FREQIHNLEDRLK 2141
Score = 53.9 bits (128), Expect = 3e-07
Identities = 59/322 (18%), Positives = 146/322 (45%), Gaps = 38/322 (11%)
Query: 62 EILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQ--------KELELVEDVWR 113
E+ EVL +RH + EL L+ + D+++ E ++++++ H KE E+
Sbjct: 692 ELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTE 751
Query: 114 GEAQDLLSQI-AQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDK 172
+D ++Q+ L+E +K L + +H V E + ++ EG ++ + +
Sbjct: 752 KALKDQINQLELLLKERDKHLKEHQAH--VENLEADIKRSEGELQQASAKLDVFQSYQSA 809
Query: 173 QRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGK----ALIEQKVE 228
++ +A + +L + + L+ ++ L K +V VEAQ K L K++
Sbjct: 810 THEQTKAYEEQLAQLQQKLLDLETERILLTK-------QVAEVEAQKKDVCTELDAHKIQ 862
Query: 229 LEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKD 288
++ +Q E++ + ++ L + + + +E+ +T+ + + + E + + +++
Sbjct: 863 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI----LVEKENMILQMRE 918
Query: 289 PNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQ 348
+ +E+ + + + + + +L EE Y+++ +E ++ + +
Sbjct: 919 GQK-----KEIEILTQKLSAKEDSIHILNEE---YETKFKNQEKKMEK----VKQKAKEM 966
Query: 349 PESGIKRLFSFFSRDKKRLANT 370
E+ K+L ++ KK L NT
Sbjct: 967 QETLKKKLLDQEAKLKKELENT 988
Score = 52.4 bits (124), Expect = 7e-07
Identities = 63/295 (21%), Positives = 129/295 (43%), Gaps = 35/295 (11%)
Query: 64 LEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQ- 122
+ V+V +H EL+ L+ + D L E++ ++++ +Q E+E + + E + LL
Sbjct: 605 ITVMVEKHKT--ELESLKHQQDALWTEKLQVLKQQ--YQTEMEKLREKCEQEKETLLKDK 660
Query: 123 ----IAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERER--QVMKKLKEVVDKQRDE 176
A ++E N++ + L K + E + R + + + LK+ DK + E
Sbjct: 661 EIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQE 720
Query: 177 IRAK-DRELGLKNEDVEA-LQQQQTRLMKINHDLRHRVTVVE----AQGKALIEQKV--- 227
+ AK D + + V++ +++ + + + L+ ++ +E + K L E +
Sbjct: 721 LEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 780
Query: 228 ELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLK 287
LEAD++ E E+ A+L + H Q EE ++ ++ +DL
Sbjct: 781 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQT--------KAYEEQLAQLQQKLLDL- 831
Query: 288 DPNRPRFTLQ------ELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQ 336
+ R T Q + +DV E + K +V L ++L SE ++ + Q
Sbjct: 832 ETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 886
Score = 44.3 bits (103), Expect = 2e-04
Identities = 36/154 (23%), Positives = 78/154 (50%), Gaps = 12/154 (7%)
Query: 97 KERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMS 156
++ KH KE+ ++ + + E + L Q L E Q++ + E +K
Sbjct: 597 EKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQ-------YQTEMEKLREKC 649
Query: 157 ERERQVMKKLKEVVDKQR-DEIRAKDRE-LGLKNEDVEALQQQQTRLMKINHDLRHRVTV 214
E+E++ + K KE++ + +E+ K E L +K ++E+L + + ++K H L ++V
Sbjct: 650 EQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSV 709
Query: 215 VEAQGKALIEQKVELEADLQTK--EQEMGSLRAE 246
++ Q + +Q++E + D Q +Q++ S+ E
Sbjct: 710 LKDQTDKM-KQELEAKMDEQKNHHQQQVDSIIKE 742
Score = 43.1 bits (100), Expect = 4e-04
Identities = 43/234 (18%), Positives = 109/234 (46%), Gaps = 19/234 (8%)
Query: 103 KELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQV 162
+ELE ++D+ E L++Q+ + +QL + K + +E + Q HE + +E ++
Sbjct: 328 QELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQD---KGMVIAETKRQMHETLEMKEEEI 384
Query: 163 MKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLM--KINHDLRHRVTVVEAQGK 220
++R++ +++ + E++ +++ R ++ L EA+ K
Sbjct: 385 A------------QLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRK 432
Query: 221 ALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEE-PETEPVGEESISDA 279
E +++ +T E+E SL+ EL ++++ + ++ EE+ + + + E+ ++
Sbjct: 433 LKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 492
Query: 280 EKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENR 333
E+ + K R R ++++ L + K+ +E+ EE+E + +
Sbjct: 493 EQ-ELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK 545
Score = 43.1 bits (100), Expect = 4e-04
Identities = 60/265 (22%), Positives = 115/265 (43%), Gaps = 38/265 (14%)
Query: 89 LERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEE 148
L R+ + KE L++ +L +Q+ QL EE L +++F +
Sbjct: 1247 LSRISHCQHRTTKVKEALLIKTC---TVSELEAQLRQLTEEQNTL-------NISFQQAT 1296
Query: 149 FQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDL 208
Q + E+E Q+ K +K ++ E A +E G + + A ++++ + ++ +L
Sbjct: 1297 HQ----LEEKENQI-KSMKADIESLVTEKEALQKEGGNQQQ---AASEKESCITQLKKEL 1348
Query: 209 RHRVTVVEAQGKALIEQKVELEA------DLQTKEQEMGSL---RAELGKLRERLQGEHS 259
+ V + L E+KVE+ + DL + Q SL A + LR++ E
Sbjct: 1349 SENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKC 1408
Query: 260 QNGEEEPE----TEPVGEESISDAEKV------AMDLKDPNRPRFTL-QELRDVLHERNE 308
+ ++ + + + +E IS E+V + K + RFT Q L + E
Sbjct: 1409 ELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE 1468
Query: 309 LKSKVFLLQEELAYYKSEEMEEENR 333
LKSK ++E EE++++N+
Sbjct: 1469 LKSKEAYEKDEQINLLKEELDQQNK 1493
Score = 42.0 bits (97), Expect = 0.001
Identities = 54/272 (19%), Positives = 128/272 (47%), Gaps = 40/272 (14%)
Query: 53 LMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVW 112
+ PK++ +E + E ++ +L + +RL++ R+ + ++HQ+ELE+++ +
Sbjct: 1913 VQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLR-KEHQQELEILKKEY 1971
Query: 113 RGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDK 172
E ++ + Q ++E+ +L N + K + EF ++++E+++ +KE ++K
Sbjct: 1972 DQEREEKIKQ----EQEDLELKHNSTLKQLM---REFNTQ--LAQKEQELEMTIKETINK 2022
Query: 173 QRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEAD 232
++ ++ E +E+ Q++ +L+K + + L E
Sbjct: 2023 AQE----------VEAELLESHQEETNQLLK----------KIAEKDDDLKRTAKRYEEI 2062
Query: 233 LQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRP 292
L +E+EM + +L E LQ ++ Q E+E E G ++++ M+L+
Sbjct: 2063 LDAREEEMTAKVRDLQTQLEELQKKYQQKLEQE---ENPGNDNVT-----IMELQTQLAQ 2114
Query: 293 RFTLQELRDVLHERNELKSKVFLLQEELAYYK 324
+ TL + D + E + ++ L++ L Y+
Sbjct: 2115 KTTL--ISDSKLKEQEFREQIHNLEDRLKKYE 2144
Score = 39.7 bits (91), Expect = 0.005
Identities = 66/329 (20%), Positives = 135/329 (41%), Gaps = 33/329 (10%)
Query: 1 MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARL--MPKVV 58
ME+++ ES LE + T I L H ++ I+ + + K +
Sbjct: 1502 MEDDKSKMEKKESNLETELKSQTAR----IMELEDHITQKTIEIESLNEVLKNYNQQKDI 1557
Query: 59 RVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRI-----EKERKHQKELELVEDVWR 113
E+++ L + E D E + L +++ E E K +KELE V +
Sbjct: 1558 EHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETK-KKELEHVNLSVK 1616
Query: 114 GEAQDLLSQIAQLQEENKQLMTNLSHK-DVNFSEEEFQKHEGMSERERQVMKKLKEVVDK 172
+ ++L + +L+ E+ + L K + + + Q M E+E Q K + + +
Sbjct: 1617 SKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSE 1676
Query: 173 QRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEAD 232
+++ ++RE+ + E +++++ Q+ + +V K + + EAD
Sbjct: 1677 LNTKLQEREREVHILEEKLKSVESSQSETL-----------IVPRSAKNVAAYTEQEEAD 1725
Query: 233 LQ-----TKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLK 287
Q T E+++ L+ L + + LQ + G+E+ ET E ++ + L+
Sbjct: 1726 SQGCVQKTYEEKISVLQRNLTEKEKLLQ----RVGQEKEETVSSHFEMRCQYQERLIKLE 1781
Query: 288 DPNRPRFTLQELRDVLHERNELKSKVFLL 316
+ Q + L E E K+K + L
Sbjct: 1782 HAEAKQHEDQSMIGHLQEELEEKNKKYSL 1810
Score = 36.2 bits (82), Expect = 0.054
Identities = 55/263 (20%), Positives = 114/263 (43%), Gaps = 38/263 (14%)
Query: 97 KERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHE--- 153
+E+K +K + +++ + LL Q A+L++E + LS K+ F+ + + +
Sbjct: 952 QEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANS 1011
Query: 154 -GMSE-------RERQVMKKLKEV---------------VDKQRDEIRA-KDRELGLKNE 189
G+S+ +++ ++ L EV +++Q +E++ + +L K +
Sbjct: 1012 AGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQ 1071
Query: 190 DVEALQQQQTRLMKINHDLRHRVTVVEAQG-------KALIEQKVELEADLQTKEQEMGS 242
+V L+Q+ ++ +T ++ +G L EQ + A + + Q+
Sbjct: 1072 EVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETK 1131
Query: 243 LRAELGKLRERLQGEHSQN---GEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQEL 299
L+A L KL L +N E+ E + + EE ++ LK + +L+
Sbjct: 1132 LKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSS 1191
Query: 300 RDVLHERNELKSKVF-LLQEELA 321
+ ++ E KS F L EELA
Sbjct: 1192 HEKSNKSLEDKSLEFKKLSEELA 1214
Score = 33.5 bits (75), Expect = 0.35
Identities = 56/249 (22%), Positives = 100/249 (40%), Gaps = 37/249 (14%)
Query: 153 EGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRV 212
E + +R R++ + L K + + A K + L Q Q + ++ +LR +
Sbjct: 137 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREEL 196
Query: 213 TVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQ------------ 260
+ + K L E E +A L+ K+Q + L+ ++ L++RL+
Sbjct: 197 QMDQQAKKHLQE---EFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEP 253
Query: 261 -----NGEEEPET--EPVGEE--SISDAEKVAMDLKDPNRPRFTLQELRDVLHERNE--- 308
EE PE+ EPV E+ S+ E + +K R L+ ++ + E
Sbjct: 254 QAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVK---RQENLLKRCKETIQSHKEQCT 310
Query: 309 -LKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFFSRDKKR- 366
L S+ LQE+L E ++E +I + Q K L +DK
Sbjct: 311 LLTSEKEALQEQL----DERLQELEKIKDLHMAEKTKLITQLRDA-KNLIEQLEQDKGMV 365
Query: 367 LANTQRNVH 375
+A T+R +H
Sbjct: 366 IAETKRQMH 374
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 57.8 bits (138), Expect = 2e-08
Identities = 86/402 (21%), Positives = 169/402 (42%), Gaps = 47/402 (11%)
Query: 15 LEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILEVLVSRHHVA 74
LE+N L D + E E +++ + + R + + V +L + ++S
Sbjct: 1437 LEENTTLLGFQDKHFQHQATIAELE--LEKTKLQELTRKLKERVTILVKQKDVLSHGEKE 1494
Query: 75 PELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLM 134
EL + +L E ++E R ++L+ + R E I L EE+ +
Sbjct: 1495 EELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNE-------ITTLNEEDS--I 1545
Query: 135 TNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDV-EA 193
+NL +N S+EE + ++E ++K+ E + KQ E++ K+++L L+N ++ +
Sbjct: 1546 SNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQK 1605
Query: 194 LQQQQTRLMKINHDLRHRVTVVEAQ-GKALIEQ--------KVELEADLQTKEQEMGSLR 244
Q Q +L ++N L + E + G + +E+ K ELE + SL
Sbjct: 1606 NSQNQEKLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLE 1665
Query: 245 AELGKLRERLQGEHSQNGEEEPETEPVGE----ESISDAEKVAMDLKDPNRPRFTLQE-L 299
AEL +++ + +N + E E + + +SD ++ + N +E L
Sbjct: 1666 AELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEAL 1725
Query: 300 RDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSF 359
+ L+ + +K LL+ +A K E+ E++ + +K
Sbjct: 1726 SEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQ----------------SASLKSQLVA 1769
Query: 360 FSRDKKRLANTQRNVHIQESFGQWANTHRDDGYTEQGQEALQ 401
+ L +T +NV++Q S D T+Q +EAL+
Sbjct: 1770 SQEKVQNLEDTVQNVNLQMS-----RMKSDLRVTQQEKEALK 1806
Score = 40.0 bits (92), Expect = 0.004
Identities = 73/319 (22%), Positives = 136/319 (42%), Gaps = 73/319 (22%)
Query: 63 ILEVLVSRHHVAPELDELRLEL-DRLRL--ERMDRI---------EKERKHQKELELVED 110
++E + +HH ++ LRLEL D++R +++D +++H+ E +E
Sbjct: 616 VIEQMKEQHH--RDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEK 673
Query: 111 VWRGEAQDLLSQIAQLQ------------------EENKQLMTNLSHKDVNFSEEEFQKH 152
+ DL ++IA+LQ EE KQL L + + E+ +H
Sbjct: 674 ----QISDLKNEIAELQGQAAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQH 729
Query: 153 E-----------GMSERERQVMKK-----------LKEVVDKQRDEIRAKDRELGLKNED 190
E ERER+ ++ +E+ ++++ + + L+ E+
Sbjct: 730 EMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEE 789
Query: 191 V--EALQQQQTRLM----KINHDLRHRVTVVEAQGKALIEQKVE-LEADLQTKEQEMGSL 243
+ E L++ Q L K+ + R + +EAQ ++ ++ E E+ LQ+ E G
Sbjct: 790 LRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTERCESALQSLE---GRY 846
Query: 244 RAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVL 303
R EL L+E+ + E SQ E E + + +E E + LK L + R++L
Sbjct: 847 RQELKDLQEQQREEKSQ---WEFEKDELTQECAEAQELLKETLKREKTTSLVLTQEREML 903
Query: 304 HE--RNELKSKVFLLQEEL 320
+ + L S V Q+ L
Sbjct: 904 EKTYKEHLNSMVVERQQLL 922
Score = 37.4 bits (85), Expect = 0.024
Identities = 52/272 (19%), Positives = 120/272 (44%), Gaps = 13/272 (4%)
Query: 80 LRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSH 139
L+ EL+R +++ + E+++ + + E L ++ ++++ ++ +LS
Sbjct: 1646 LKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHR--CPDLSD 1703
Query: 140 KDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQT 199
S + + E+E + ++L VDK + R +K E ++ + Q
Sbjct: 1704 FQQKISSVLSYNEKLLKEKEA-LSEELNSCVDKLAKSSLLEHRIATMKQEQ-KSWEHQSA 1761
Query: 200 RLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHS 259
L + +V +E + + Q +++DL+ +QE +L+ E+ L ++LQ
Sbjct: 1762 SLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSLHKQLQNAGG 1821
Query: 260 QNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNE-LKSKVFLLQE 318
++ E T P G + ++++ D D + E + +L + NE L++ V +
Sbjct: 1822 KSWAPEIATHPSGLH--NQQKRLSWDKLD-----HLMNEEQQLLWQENERLQTMVQNTKA 1874
Query: 319 ELAYYKSEEME-EENRIPQPPPIAHPRTSPQP 349
EL + + + + E N +P+ +P + P
Sbjct: 1875 ELTHSREKVRQLESNLLPKHQKHLNPSGTMNP 1906
Score = 35.8 bits (81), Expect = 0.071
Identities = 71/346 (20%), Positives = 147/346 (42%), Gaps = 59/346 (17%)
Query: 34 VGHEFERVIDQ--HGCEAIARLMPKVVRVLEILEVLVSRHHVAPE---------LDELRL 82
+ H ERV DQ E + + K ++ ++ V HH A E LDE
Sbjct: 375 IRHLLERV-DQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYK 433
Query: 83 EL-----DRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNL 137
E + LR ER +++ K + ELE + + E + ++A +EN +L L
Sbjct: 434 ERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEENYIRDRLALSLKENSRLENEL 493
Query: 138 SHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQ 197
+ E+ ++E ++ + + + L+ V+ ++ ++ E L+ E + ++ +
Sbjct: 494 LE-----NAEKLAEYENLTNK---LQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNE 545
Query: 198 QTRLMKINHD----LRHRVTVVEAQGKAL-----IEQKVELEADLQTKEQEMG------- 241
R ++ D L+ + AQG+ L E+EA+ E E G
Sbjct: 546 YERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHGLGSEECN 605
Query: 242 ----SLRAELGKLRERLQGEHSQN--------GEEEPETEPVGEESISDAEKVAMDLKD- 288
S+ AEL + E+++ +H ++ ++ E +E++ +K ++K
Sbjct: 606 PLNMSIEAEL--VIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQR 663
Query: 289 -PNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENR 333
N +++ D+ +E EL+ + +L+E A++++ EE +
Sbjct: 664 HENETHTLEKQISDLKNEIAELQGQAAVLKE--AHHEATCRHEEEK 707
Score = 30.4 bits (67), Expect = 3.0
Identities = 36/159 (22%), Positives = 70/159 (44%), Gaps = 21/159 (13%)
Query: 173 QRDEIRAKDRELGLKN-EDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEA 231
QR E++ ++ E ++ ++E ++ +T ++ + + L EQ + L A
Sbjct: 1170 QRQEVKIEESEASVEGFSELENSEETRTESWELKNQISQ-----------LQEQLMMLCA 1218
Query: 232 DLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNR 291
D ++ L ++ L+++L+ E PE P + D + L++ R
Sbjct: 1219 DCDRASEKKQDLLFDVSVLKKKLKML-----ERIPEASPKYKLLYEDVSRENDCLQEELR 1273
Query: 292 PRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEE 330
T + + L EL ++VF LQ+EL K EE+ E
Sbjct: 1274 MMETRYD--EALENNKELTAEVFRLQDELK--KMEEVTE 1308
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 57.8 bits (138), Expect = 2e-08
Identities = 86/402 (21%), Positives = 169/402 (42%), Gaps = 47/402 (11%)
Query: 15 LEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILEVLVSRHHVA 74
LE+N L D + E E +++ + + R + + V +L + ++S
Sbjct: 1431 LEENTTLLGFQDKHFQHQATIAELE--LEKTKLQELTRKLKERVTILVKQKDVLSHGEKE 1488
Query: 75 PELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLM 134
EL + +L E ++E R ++L+ + R E I L EE+ +
Sbjct: 1489 EELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNE-------ITTLNEEDS--I 1539
Query: 135 TNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDV-EA 193
+NL +N S+EE + ++E ++K+ E + KQ E++ K+++L L+N ++ +
Sbjct: 1540 SNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQK 1599
Query: 194 LQQQQTRLMKINHDLRHRVTVVEAQ-GKALIEQ--------KVELEADLQTKEQEMGSLR 244
Q Q +L ++N L + E + G + +E+ K ELE + SL
Sbjct: 1600 NSQNQEKLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLE 1659
Query: 245 AELGKLRERLQGEHSQNGEEEPETEPVGE----ESISDAEKVAMDLKDPNRPRFTLQE-L 299
AEL +++ + +N + E E + + +SD ++ + N +E L
Sbjct: 1660 AELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEAL 1719
Query: 300 RDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSF 359
+ L+ + +K LL+ +A K E+ E++ + +K
Sbjct: 1720 SEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQ----------------SASLKSQLVA 1763
Query: 360 FSRDKKRLANTQRNVHIQESFGQWANTHRDDGYTEQGQEALQ 401
+ L +T +NV++Q S D T+Q +EAL+
Sbjct: 1764 SQEKVQNLEDTVQNVNLQMS-----RMKSDLRVTQQEKEALK 1800
Score = 40.0 bits (92), Expect = 0.004
Identities = 73/319 (22%), Positives = 136/319 (42%), Gaps = 73/319 (22%)
Query: 63 ILEVLVSRHHVAPELDELRLEL-DRLRL--ERMDRI---------EKERKHQKELELVED 110
++E + +HH ++ LRLEL D++R +++D +++H+ E +E
Sbjct: 610 VIEQMKEQHH--RDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEK 667
Query: 111 VWRGEAQDLLSQIAQLQ------------------EENKQLMTNLSHKDVNFSEEEFQKH 152
+ DL ++IA+LQ EE KQL L + + E+ +H
Sbjct: 668 ----QISDLKNEIAELQGQAAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQH 723
Query: 153 E-----------GMSERERQVMKK-----------LKEVVDKQRDEIRAKDRELGLKNED 190
E ERER+ ++ +E+ ++++ + + L+ E+
Sbjct: 724 EMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEE 783
Query: 191 V--EALQQQQTRLM----KINHDLRHRVTVVEAQGKALIEQKVE-LEADLQTKEQEMGSL 243
+ E L++ Q L K+ + R + +EAQ ++ ++ E E+ LQ+ E G
Sbjct: 784 LRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTERCESALQSLE---GRY 840
Query: 244 RAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVL 303
R EL L+E+ + E SQ E E + + +E E + LK L + R++L
Sbjct: 841 RQELKDLQEQQREEKSQ---WEFEKDELTQECAEAQELLKETLKREKTTSLVLTQEREML 897
Query: 304 HE--RNELKSKVFLLQEEL 320
+ + L S V Q+ L
Sbjct: 898 EKTYKEHLNSMVVERQQLL 916
Score = 37.4 bits (85), Expect = 0.024
Identities = 52/272 (19%), Positives = 120/272 (44%), Gaps = 13/272 (4%)
Query: 80 LRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSH 139
L+ EL+R +++ + E+++ + + E L ++ ++++ ++ +LS
Sbjct: 1640 LKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHR--CPDLSD 1697
Query: 140 KDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQT 199
S + + E+E + ++L VDK + R +K E ++ + Q
Sbjct: 1698 FQQKISSVLSYNEKLLKEKEA-LSEELNSCVDKLAKSSLLEHRIATMKQEQ-KSWEHQSA 1755
Query: 200 RLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHS 259
L + +V +E + + Q +++DL+ +QE +L+ E+ L ++LQ
Sbjct: 1756 SLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSLHKQLQNAGG 1815
Query: 260 QNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNE-LKSKVFLLQE 318
++ E T P G + ++++ D D + E + +L + NE L++ V +
Sbjct: 1816 KSWAPEIATHPSGLH--NQQKRLSWDKLD-----HLMNEEQQLLWQENERLQTMVQNTKA 1868
Query: 319 ELAYYKSEEME-EENRIPQPPPIAHPRTSPQP 349
EL + + + + E N +P+ +P + P
Sbjct: 1869 ELTHSREKVRQLESNLLPKHQKHLNPSGTMNP 1900
Score = 35.8 bits (81), Expect = 0.071
Identities = 71/346 (20%), Positives = 147/346 (42%), Gaps = 59/346 (17%)
Query: 34 VGHEFERVIDQ--HGCEAIARLMPKVVRVLEILEVLVSRHHVAPE---------LDELRL 82
+ H ERV DQ E + + K ++ ++ V HH A E LDE
Sbjct: 369 IRHLLERV-DQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYK 427
Query: 83 EL-----DRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNL 137
E + LR ER +++ K + ELE + + E + ++A +EN +L L
Sbjct: 428 ERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEENYIRDRLALSLKENSRLENEL 487
Query: 138 SHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQ 197
+ E+ ++E ++ + + + L+ V+ ++ ++ E L+ E + ++ +
Sbjct: 488 LE-----NAEKLAEYENLTNK---LQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNE 539
Query: 198 QTRLMKINHD----LRHRVTVVEAQGKAL-----IEQKVELEADLQTKEQEMG------- 241
R ++ D L+ + AQG+ L E+EA+ E E G
Sbjct: 540 YERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHGLGSEECN 599
Query: 242 ----SLRAELGKLRERLQGEHSQN--------GEEEPETEPVGEESISDAEKVAMDLKD- 288
S+ AEL + E+++ +H ++ ++ E +E++ +K ++K
Sbjct: 600 PLNMSIEAEL--VIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQR 657
Query: 289 -PNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENR 333
N +++ D+ +E EL+ + +L+E A++++ EE +
Sbjct: 658 HENETHTLEKQISDLKNEIAELQGQAAVLKE--AHHEATCRHEEEK 701
Score = 30.4 bits (67), Expect = 3.0
Identities = 36/159 (22%), Positives = 70/159 (44%), Gaps = 21/159 (13%)
Query: 173 QRDEIRAKDRELGLKN-EDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEA 231
QR E++ ++ E ++ ++E ++ +T ++ + + L EQ + L A
Sbjct: 1164 QRQEVKIEESEASVEGFSELENSEETRTESWELKNQISQ-----------LQEQLMMLCA 1212
Query: 232 DLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNR 291
D ++ L ++ L+++L+ E PE P + D + L++ R
Sbjct: 1213 DCDRASEKKQDLLFDVSVLKKKLKML-----ERIPEASPKYKLLYEDVSRENDCLQEELR 1267
Query: 292 PRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEE 330
T + + L EL ++VF LQ+EL K EE+ E
Sbjct: 1268 MMETRYD--EALENNKELTAEVFRLQDELK--KMEEVTE 1302
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 57.8 bits (138), Expect = 2e-08
Identities = 86/402 (21%), Positives = 169/402 (42%), Gaps = 47/402 (11%)
Query: 15 LEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILEVLVSRHHVA 74
LE+N L D + E E +++ + + R + + V +L + ++S
Sbjct: 1431 LEENTTLLGFQDKHFQHQATIAELE--LEKTKLQELTRKLKERVTILVKQKDVLSHGEKE 1488
Query: 75 PELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLM 134
EL + +L E ++E R ++L+ + R E I L EE+ +
Sbjct: 1489 EELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNE-------ITTLNEEDS--I 1539
Query: 135 TNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDV-EA 193
+NL +N S+EE + ++E ++K+ E + KQ E++ K+++L L+N ++ +
Sbjct: 1540 SNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQK 1599
Query: 194 LQQQQTRLMKINHDLRHRVTVVEAQ-GKALIEQ--------KVELEADLQTKEQEMGSLR 244
Q Q +L ++N L + E + G + +E+ K ELE + SL
Sbjct: 1600 NSQNQEKLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLE 1659
Query: 245 AELGKLRERLQGEHSQNGEEEPETEPVGE----ESISDAEKVAMDLKDPNRPRFTLQE-L 299
AEL +++ + +N + E E + + +SD ++ + N +E L
Sbjct: 1660 AELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEAL 1719
Query: 300 RDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSF 359
+ L+ + +K LL+ +A K E+ E++ + +K
Sbjct: 1720 SEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQ----------------SASLKSQLVA 1763
Query: 360 FSRDKKRLANTQRNVHIQESFGQWANTHRDDGYTEQGQEALQ 401
+ L +T +NV++Q S D T+Q +EAL+
Sbjct: 1764 SQEKVQNLEDTVQNVNLQMS-----RMKSDLRVTQQEKEALK 1800
Score = 40.0 bits (92), Expect = 0.004
Identities = 73/319 (22%), Positives = 136/319 (42%), Gaps = 73/319 (22%)
Query: 63 ILEVLVSRHHVAPELDELRLEL-DRLRL--ERMDRI---------EKERKHQKELELVED 110
++E + +HH ++ LRLEL D++R +++D +++H+ E +E
Sbjct: 610 VIEQMKEQHH--RDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEK 667
Query: 111 VWRGEAQDLLSQIAQLQ------------------EENKQLMTNLSHKDVNFSEEEFQKH 152
+ DL ++IA+LQ EE KQL L + + E+ +H
Sbjct: 668 ----QISDLKNEIAELQGQAAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQH 723
Query: 153 E-----------GMSERERQVMKK-----------LKEVVDKQRDEIRAKDRELGLKNED 190
E ERER+ ++ +E+ ++++ + + L+ E+
Sbjct: 724 EMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEE 783
Query: 191 V--EALQQQQTRLM----KINHDLRHRVTVVEAQGKALIEQKVE-LEADLQTKEQEMGSL 243
+ E L++ Q L K+ + R + +EAQ ++ ++ E E+ LQ+ E G
Sbjct: 784 LRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTERCESALQSLE---GRY 840
Query: 244 RAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVL 303
R EL L+E+ + E SQ E E + + +E E + LK L + R++L
Sbjct: 841 RQELKDLQEQQREEKSQ---WEFEKDELTQECAEAQELLKETLKREKTTSLVLTQEREML 897
Query: 304 HE--RNELKSKVFLLQEEL 320
+ + L S V Q+ L
Sbjct: 898 EKTYKEHLNSMVVERQQLL 916
Score = 37.4 bits (85), Expect = 0.024
Identities = 52/272 (19%), Positives = 120/272 (44%), Gaps = 13/272 (4%)
Query: 80 LRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSH 139
L+ EL+R +++ + E+++ + + E L ++ ++++ ++ +LS
Sbjct: 1640 LKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHR--CPDLSD 1697
Query: 140 KDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQT 199
S + + E+E + ++L VDK + R +K E ++ + Q
Sbjct: 1698 FQQKISSVLSYNEKLLKEKEA-LSEELNSCVDKLAKSSLLEHRIATMKQEQ-KSWEHQSA 1755
Query: 200 RLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHS 259
L + +V +E + + Q +++DL+ +QE +L+ E+ L ++LQ
Sbjct: 1756 SLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSLHKQLQNAGG 1815
Query: 260 QNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNE-LKSKVFLLQE 318
++ E T P G + ++++ D D + E + +L + NE L++ V +
Sbjct: 1816 KSWAPEIATHPSGLH--NQQKRLSWDKLD-----HLMNEEQQLLWQENERLQTMVQNTKA 1868
Query: 319 ELAYYKSEEME-EENRIPQPPPIAHPRTSPQP 349
EL + + + + E N +P+ +P + P
Sbjct: 1869 ELTHSREKVRQLESNLLPKHQKHLNPSGTMNP 1900
Score = 35.8 bits (81), Expect = 0.071
Identities = 71/346 (20%), Positives = 147/346 (42%), Gaps = 59/346 (17%)
Query: 34 VGHEFERVIDQ--HGCEAIARLMPKVVRVLEILEVLVSRHHVAPE---------LDELRL 82
+ H ERV DQ E + + K ++ ++ V HH A E LDE
Sbjct: 369 IRHLLERV-DQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYK 427
Query: 83 EL-----DRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNL 137
E + LR ER +++ K + ELE + + E + ++A +EN +L L
Sbjct: 428 ERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEENYIRDRLALSLKENSRLENEL 487
Query: 138 SHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQ 197
+ E+ ++E ++ + + + L+ V+ ++ ++ E L+ E + ++ +
Sbjct: 488 LE-----NAEKLAEYENLTNK---LQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNE 539
Query: 198 QTRLMKINHD----LRHRVTVVEAQGKAL-----IEQKVELEADLQTKEQEMG------- 241
R ++ D L+ + AQG+ L E+EA+ E E G
Sbjct: 540 YERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHGLGSEECN 599
Query: 242 ----SLRAELGKLRERLQGEHSQN--------GEEEPETEPVGEESISDAEKVAMDLKD- 288
S+ AEL + E+++ +H ++ ++ E +E++ +K ++K
Sbjct: 600 PLNMSIEAEL--VIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQR 657
Query: 289 -PNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENR 333
N +++ D+ +E EL+ + +L+E A++++ EE +
Sbjct: 658 HENETHTLEKQISDLKNEIAELQGQAAVLKE--AHHEATCRHEEEK 701
Score = 30.4 bits (67), Expect = 3.0
Identities = 36/159 (22%), Positives = 70/159 (44%), Gaps = 21/159 (13%)
Query: 173 QRDEIRAKDRELGLKN-EDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEA 231
QR E++ ++ E ++ ++E ++ +T ++ + + L EQ + L A
Sbjct: 1164 QRQEVKIEESEASVEGFSELENSEETRTESWELKNQISQ-----------LQEQLMMLCA 1212
Query: 232 DLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNR 291
D ++ L ++ L+++L+ E PE P + D + L++ R
Sbjct: 1213 DCDRASEKKQDLLFDVSVLKKKLKML-----ERIPEASPKYKLLYEDVSRENDCLQEELR 1267
Query: 292 PRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEE 330
T + + L EL ++VF LQ+EL K EE+ E
Sbjct: 1268 MMETRYD--EALENNKELTAEVFRLQDELK--KMEEVTE 1302
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 57.8 bits (138), Expect = 2e-08
Identities = 86/402 (21%), Positives = 169/402 (42%), Gaps = 47/402 (11%)
Query: 15 LEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILEVLVSRHHVA 74
LE+N L D + E E +++ + + R + + V +L + ++S
Sbjct: 1431 LEENTTLLGFQDKHFQHQATIAELE--LEKTKLQELTRKLKERVTILVKQKDVLSHGEKE 1488
Query: 75 PELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLM 134
EL + +L E ++E R ++L+ + R E I L EE+ +
Sbjct: 1489 EELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNE-------ITTLNEEDS--I 1539
Query: 135 TNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDV-EA 193
+NL +N S+EE + ++E ++K+ E + KQ E++ K+++L L+N ++ +
Sbjct: 1540 SNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQK 1599
Query: 194 LQQQQTRLMKINHDLRHRVTVVEAQ-GKALIEQ--------KVELEADLQTKEQEMGSLR 244
Q Q +L ++N L + E + G + +E+ K ELE + SL
Sbjct: 1600 NSQNQEKLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLE 1659
Query: 245 AELGKLRERLQGEHSQNGEEEPETEPVGE----ESISDAEKVAMDLKDPNRPRFTLQE-L 299
AEL +++ + +N + E E + + +SD ++ + N +E L
Sbjct: 1660 AELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEAL 1719
Query: 300 RDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSF 359
+ L+ + +K LL+ +A K E+ E++ + +K
Sbjct: 1720 SEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQ----------------SASLKSQLVA 1763
Query: 360 FSRDKKRLANTQRNVHIQESFGQWANTHRDDGYTEQGQEALQ 401
+ L +T +NV++Q S D T+Q +EAL+
Sbjct: 1764 SQEKVQNLEDTVQNVNLQMS-----RMKSDLRVTQQEKEALK 1800
Score = 40.0 bits (92), Expect = 0.004
Identities = 73/319 (22%), Positives = 136/319 (42%), Gaps = 73/319 (22%)
Query: 63 ILEVLVSRHHVAPELDELRLEL-DRLRL--ERMDRI---------EKERKHQKELELVED 110
++E + +HH ++ LRLEL D++R +++D +++H+ E +E
Sbjct: 610 VIEQMKEQHH--RDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEK 667
Query: 111 VWRGEAQDLLSQIAQLQ------------------EENKQLMTNLSHKDVNFSEEEFQKH 152
+ DL ++IA+LQ EE KQL L + + E+ +H
Sbjct: 668 ----QISDLKNEIAELQGQAAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQH 723
Query: 153 E-----------GMSERERQVMKK-----------LKEVVDKQRDEIRAKDRELGLKNED 190
E ERER+ ++ +E+ ++++ + + L+ E+
Sbjct: 724 EMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEE 783
Query: 191 V--EALQQQQTRLM----KINHDLRHRVTVVEAQGKALIEQKVE-LEADLQTKEQEMGSL 243
+ E L++ Q L K+ + R + +EAQ ++ ++ E E+ LQ+ E G
Sbjct: 784 LRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTERCESALQSLE---GRY 840
Query: 244 RAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVL 303
R EL L+E+ + E SQ E E + + +E E + LK L + R++L
Sbjct: 841 RQELKDLQEQQREEKSQ---WEFEKDELTQECAEAQELLKETLKREKTTSLVLTQEREML 897
Query: 304 HE--RNELKSKVFLLQEEL 320
+ + L S V Q+ L
Sbjct: 898 EKTYKEHLNSMVVERQQLL 916
Score = 37.4 bits (85), Expect = 0.024
Identities = 52/272 (19%), Positives = 120/272 (44%), Gaps = 13/272 (4%)
Query: 80 LRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSH 139
L+ EL+R +++ + E+++ + + E L ++ ++++ ++ +LS
Sbjct: 1640 LKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHR--CPDLSD 1697
Query: 140 KDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQT 199
S + + E+E + ++L VDK + R +K E ++ + Q
Sbjct: 1698 FQQKISSVLSYNEKLLKEKEA-LSEELNSCVDKLAKSSLLEHRIATMKQEQ-KSWEHQSA 1755
Query: 200 RLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHS 259
L + +V +E + + Q +++DL+ +QE +L+ E+ L ++LQ
Sbjct: 1756 SLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSLHKQLQNAGG 1815
Query: 260 QNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNE-LKSKVFLLQE 318
++ E T P G + ++++ D D + E + +L + NE L++ V +
Sbjct: 1816 KSWAPEIATHPSGLH--NQQKRLSWDKLD-----HLMNEEQQLLWQENERLQTMVQNTKA 1868
Query: 319 ELAYYKSEEME-EENRIPQPPPIAHPRTSPQP 349
EL + + + + E N +P+ +P + P
Sbjct: 1869 ELTHSREKVRQLESNLLPKHQKHLNPSGTMNP 1900
Score = 35.8 bits (81), Expect = 0.071
Identities = 71/346 (20%), Positives = 147/346 (42%), Gaps = 59/346 (17%)
Query: 34 VGHEFERVIDQ--HGCEAIARLMPKVVRVLEILEVLVSRHHVAPE---------LDELRL 82
+ H ERV DQ E + + K ++ ++ V HH A E LDE
Sbjct: 369 IRHLLERV-DQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYK 427
Query: 83 EL-----DRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNL 137
E + LR ER +++ K + ELE + + E + ++A +EN +L L
Sbjct: 428 ERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEENYIRDRLALSLKENSRLENEL 487
Query: 138 SHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQ 197
+ E+ ++E ++ + + + L+ V+ ++ ++ E L+ E + ++ +
Sbjct: 488 LE-----NAEKLAEYENLTNK---LQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNE 539
Query: 198 QTRLMKINHD----LRHRVTVVEAQGKAL-----IEQKVELEADLQTKEQEMG------- 241
R ++ D L+ + AQG+ L E+EA+ E E G
Sbjct: 540 YERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHGLGSEECN 599
Query: 242 ----SLRAELGKLRERLQGEHSQN--------GEEEPETEPVGEESISDAEKVAMDLKD- 288
S+ AEL + E+++ +H ++ ++ E +E++ +K ++K
Sbjct: 600 PLNMSIEAEL--VIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQR 657
Query: 289 -PNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENR 333
N +++ D+ +E EL+ + +L+E A++++ EE +
Sbjct: 658 HENETHTLEKQISDLKNEIAELQGQAAVLKE--AHHEATCRHEEEK 701
Score = 30.4 bits (67), Expect = 3.0
Identities = 36/159 (22%), Positives = 70/159 (44%), Gaps = 21/159 (13%)
Query: 173 QRDEIRAKDRELGLKN-EDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEA 231
QR E++ ++ E ++ ++E ++ +T ++ + + L EQ + L A
Sbjct: 1164 QRQEVKIEESEASVEGFSELENSEETRTESWELKNQISQ-----------LQEQLMMLCA 1212
Query: 232 DLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNR 291
D ++ L ++ L+++L+ E PE P + D + L++ R
Sbjct: 1213 DCDRASEKKQDLLFDVSVLKKKLKML-----ERIPEASPKYKLLYEDVSRENDCLQEELR 1267
Query: 292 PRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEE 330
T + + L EL ++VF LQ+EL K EE+ E
Sbjct: 1268 MMETRYD--EALENNKELTAEVFRLQDELK--KMEEVTE 1302
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,120,633
Number of Sequences: 37866
Number of extensions: 736491
Number of successful extensions: 9131
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 248
Number of HSP's successfully gapped in prelim test: 1023
Number of HSP's that attempted gapping in prelim test: 4995
Number of HSP's gapped (non-prelim): 3301
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.