Guide to the Human Genome
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Search of human proteins with 194578885

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194578885 calumenin isoform b precursor [Homo sapiens]
         (315 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194578885 calumenin isoform b precursor [Homo sapiens]             659   0.0  
gi|4502551 calumenin isoform a precursor [Homo sapiens]               614   e-176
gi|4506455 reticulocalbin 1 precursor [Homo sapiens]                  402   e-112
gi|28626510 reticulocalbin 3, EF-hand calcium binding domain [Ho...   331   6e-91
gi|4506457 reticulocalbin 2 precursor [Homo sapiens]                  228   7e-60
gi|18699732 stromal cell derived factor 4 isoform 2 precursor [H...   122   3e-28
gi|7706573 stromal cell derived factor 4 isoform 1 precursor [Ho...    94   1e-19
gi|4885111 calmodulin-like 3 [Homo sapiens]                            47   2e-05
gi|4507617 fast skeletal muscle troponin C [Homo sapiens]              45   6e-05
gi|58218968 calmodulin 3 [Homo sapiens]                                45   8e-05
gi|4502549 calmodulin 2 [Homo sapiens]                                 45   8e-05
gi|5901912 calmodulin 1 [Homo sapiens]                                 45   8e-05
gi|4507615 troponin C, slow [Homo sapiens]                             45   8e-05
gi|215983090 guanylate cyclase activator 1C [Homo sapiens]             40   0.002
gi|13929432 calcium binding protein 1 isoform 1 [Homo sapiens]         39   0.005
gi|110835715 calcyphosine-like [Homo sapiens]                          39   0.005
gi|110835717 calcyphosine-like [Homo sapiens]                          39   0.005
gi|76056882 calcium binding protein 1 isoform 3 [Homo sapiens]         38   0.010
gi|13929434 calcium binding protein 1 isoform 2 [Homo sapiens]         38   0.010
gi|78190488 Kv channel interacting protein 4 isoform 3 [Homo sap...    38   0.013
gi|78190486 Kv channel interacting protein 4 isoform 5 [Homo sap...    38   0.013
gi|22212902 Kv channel interacting protein 4 isoform 4 [Homo sap...    38   0.013
gi|22212900 Kv channel interacting protein 4 isoform 3 [Homo sap...    38   0.013
gi|22212898 Kv channel interacting protein 4 isoform 2 [Homo sap...    38   0.013
gi|24586671 Kv channel interacting protein 4 isoform 1 [Homo sap...    38   0.013
gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...    37   0.017
gi|194595509 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...    37   0.017
gi|110611180 calcium binding protein 2 isoform 2 [Homo sapiens]        37   0.023
gi|110611178 calcium binding protein 2 isoform 1 [Homo sapiens]        37   0.023
gi|15055537 secretagogin precursor [Homo sapiens]                      37   0.030

>gi|194578885 calumenin isoform b precursor [Homo sapiens]
          Length = 315

 Score =  659 bits (1700), Expect = 0.0
 Identities = 315/315 (100%), Positives = 315/315 (100%)

Query: 1   MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKT 60
           MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKT
Sbjct: 1   MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKT 60

Query: 61  FDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMNQ 120
           FDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMNQ
Sbjct: 61  FDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMNQ 120

Query: 121 DGLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFL 180
           DGLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFL
Sbjct: 121 DGLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFL 180

Query: 181 HPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEF 240
           HPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEF
Sbjct: 181 HPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEF 240

Query: 241 RDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGS 300
           RDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGS
Sbjct: 241 RDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGS 300

Query: 301 QATDFGEALVRHDEF 315
           QATDFGEALVRHDEF
Sbjct: 301 QATDFGEALVRHDEF 315


>gi|4502551 calumenin isoform a precursor [Homo sapiens]
          Length = 315

 Score =  614 bits (1583), Expect = e-176
 Identities = 292/315 (92%), Positives = 302/315 (95%)

Query: 1   MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKT 60
           MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKT
Sbjct: 1   MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKT 60

Query: 61  FDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMNQ 120
           FDQLTPEESKERLG IV KID DKDGFVT  ELK WIK AQK++IY++VE QW+  D+N+
Sbjct: 61  FDQLTPEESKERLGKIVSKIDGDKDGFVTVDELKDWIKFAQKRWIYEDVERQWKGHDLNE 120

Query: 121 DGLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFL 180
           DGL+SW+EY+N TYG  LDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFL
Sbjct: 121 DGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFL 180

Query: 181 HPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEF 240
           HPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEF
Sbjct: 181 HPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEF 240

Query: 241 RDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGS 300
           RDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGS
Sbjct: 241 RDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGS 300

Query: 301 QATDFGEALVRHDEF 315
           QATDFGEALVRHDEF
Sbjct: 301 QATDFGEALVRHDEF 315


>gi|4506455 reticulocalbin 1 precursor [Homo sapiens]
          Length = 331

 Score =  402 bits (1033), Expect = e-112
 Identities = 192/314 (61%), Positives = 246/314 (78%), Gaps = 6/314 (1%)

Query: 7   LMCLSLCTAFALSKPTEKKDRV-HHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKTFDQLT 65
           L+ L L      +KPT +K+RV   + +L ++   D QSF YDH+AFLG E++KTFDQLT
Sbjct: 17  LLALVLAPRVLRAKPTVRKERVVRPDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLT 76

Query: 66  PEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMNQDGLIS 125
           P+ESKERLG IVD+ID D DGFVT  ELK+WIK  QK+YI+DNV   W+++D ++D  IS
Sbjct: 77  PDESKERLGKIVDRIDNDGDGFVTTEELKTWIKRVQKRYIFDNVAKVWKDYDRDKDDKIS 136

Query: 126 WDEYRNVTYGTYLDDP----DPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLH 181
           W+EY+  TYG YL +P    D  D   +K+M+ RDERRFK AD +GDL AT+EEFTAFLH
Sbjct: 137 WEEYKQATYGYYLGNPAEFHDSSDHHTFKKMLPRDERRFKAADLNGDLTATREEFTAFLH 196

Query: 182 PEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFR 241
           PEE+++MK+IVV ET+EDIDKN DGF+D +EYI DM+SH+ N  EP+WV +EREQF EFR
Sbjct: 197 PEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEENGPEPDWVLSEREQFNEFR 256

Query: 242 DKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQ 301
           D N+DGK+DK+E + WILP DYDHA+AEARHLVYESD+NKD KLTKEEI++ +++FVGSQ
Sbjct: 257 DLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEKLTKEEILENWNMFVGSQ 316

Query: 302 ATDFGEALVR-HDE 314
           AT++GE L + HDE
Sbjct: 317 ATNYGEDLTKNHDE 330


>gi|28626510 reticulocalbin 3, EF-hand calcium binding domain [Homo
           sapiens]
          Length = 328

 Score =  331 bits (848), Expect = 6e-91
 Identities = 161/319 (50%), Positives = 222/319 (69%), Gaps = 11/319 (3%)

Query: 7   LMCLSLCTAFALSKPTEK-----KDRVHHEPQLSDKVHNDAQ-SFDYDHDAFLGAEEAKT 60
           L+ L L    A  KP+       + RVH    LSD  H+DA  +F YDH+AFLG E AK 
Sbjct: 8   LLLLLLLRHGAQGKPSPDAGPHGQGRVHQAAPLSDAPHDDAHGNFQYDHEAFLGREVAKE 67

Query: 61  FDQLTPEESKERLGMIVDKID--ADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDM 118
           FDQLTPEES+ RLG IVD++D   D DG+V+  EL++WI H Q+++I D+V   W  +D 
Sbjct: 68  FDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRHIRDSVSAAWDTYDT 127

Query: 119 NQDGLISWDEYRNVTYGTYLDDP---DPDDGFNYKQMMVRDERRFKMADKDGDLIATKEE 175
           ++DG + W+E RN TYG Y       D +D   YK+M+ RDERRF++AD+DGD +AT+EE
Sbjct: 128 DRDGRVGWEELRNATYGHYAPGEEFHDVEDAETYKKMLARDERRFRVADQDGDSMATREE 187

Query: 176 FTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTERE 235
            TAFLHPEE+ +M+DIV+ ET+ED+D+N DG++ +EEYI D+YS +   +EP WV+TER+
Sbjct: 188 LTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYSAEPGEEEPAWVQTERQ 247

Query: 236 QFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYD 295
           QF +FRD N+DG +D  E   W+LP   D    EA HL++ESD +KDG+L+K EI+  ++
Sbjct: 248 QFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESDTDKDGRLSKAEILGNWN 307

Query: 296 LFVGSQATDFGEALVRHDE 314
           +FVGSQAT++GE L RH +
Sbjct: 308 MFVGSQATNYGEDLTRHHD 326


>gi|4506457 reticulocalbin 2 precursor [Homo sapiens]
          Length = 317

 Score =  228 bits (580), Expect = 7e-60
 Identities = 114/279 (40%), Positives = 176/279 (63%), Gaps = 14/279 (5%)

Query: 46  DYDHDAFLGAEE-AKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKY 104
           DYD +A LG +E    + +L  EE ++RL  I+ KID D DGF+TE EL SWI+ + K Y
Sbjct: 38  DYDREALLGVQEDVDEYVKLGHEEQQKRLQAIIKKIDLDSDGFLTESELSSWIQMSFKHY 97

Query: 105 IYDNVENQWQEFDMNQDGLISWDEYRNVTY--------GTYLDDPDPDDGFNYKQMMVRD 156
                + Q+ E+D N D  ++WDEY    Y         T LDD + +   +++++ ++D
Sbjct: 98  AMQEAKQQFVEYDKNSDDTVTWDEYNIQMYDRVIDFDENTALDDAEEE---SFRKLHLKD 154

Query: 157 ERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGD 216
           ++RF+ A++D     + EEF AF HPEE DYM + V+QE +E+ DKN DGF+ LEE++GD
Sbjct: 155 KKRFEKANQDSGPGLSLEEFIAFEHPEEVDYMTEFVIQEALEEHDKNGDGFVSLEEFLGD 214

Query: 217 MYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYE 276
                   ++PEW+  E+++FV   DK+ DG++D +E   W++P++   A+ EA HL+ E
Sbjct: 215 YRWDPTANEDPEWILVEKDRFVNDYDKDNDGRLDPQELLPWVVPNNQGIAQEEALHLIDE 274

Query: 277 SDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF 315
            D N D KL++EEI++  DLF+ S+ATD+G  L  HD++
Sbjct: 275 MDLNGDKKLSEEEILENPDLFLTSEATDYGRQL--HDDY 311


>gi|18699732 stromal cell derived factor 4 isoform 2 precursor [Homo
           sapiens]
          Length = 362

 Score =  122 bits (307), Expect = 3e-28
 Identities = 75/288 (26%), Positives = 141/288 (48%), Gaps = 21/288 (7%)

Query: 47  YDHDAFLGAEEAKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIY 106
           +  + FLG +     +   P  S+ +L +I  K+D + D  ++  E++ WI     ++  
Sbjct: 77  FHQEVFLGKDLGGFDEDAEPRRSRRKLMVIFSKVDVNTDRKISAKEMQRWIMEKTAEHFQ 136

Query: 107 DNVENQWQEF---DMNQDGLISWDEYR------------NVTYGTYLDDPDPDDGFNYKQ 151
           + +E     F   D + DG +SWDEY+             V     L++    D    + 
Sbjct: 137 EAMEESKTHFRAVDPDGDGHVSWDEYKVKFLASKGHSEKEVADAIRLNEELKVDEETQEV 196

Query: 152 MMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLE 211
           +    +R ++      DL+ T+EEF +FLHPE    M   +V+E + D+D++ D  + + 
Sbjct: 197 LENLKDRWYQADSPPADLLLTEEEFLSFLHPEHSRGMLRFMVKEIVRDLDQDGDKQLSVP 256

Query: 212 EYI----GDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAE 267
           E+I    G + +  G   +  WVK  +++F E  D N DG +  EE + ++ P +  +A 
Sbjct: 257 EFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTAEELESYMDPMNEYNAL 316

Query: 268 AEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF 315
            EA+ ++  +D+N++  L  EE++   + F GS+  D+  ++  H+EF
Sbjct: 317 NEAKQMIAVADENQNHHLEPEEVLKYSEFFTGSKLVDYARSV--HEEF 362


>gi|7706573 stromal cell derived factor 4 isoform 1 precursor [Homo
           sapiens]
          Length = 348

 Score = 94.4 bits (233), Expect = 1e-19
 Identities = 59/229 (25%), Positives = 107/229 (46%), Gaps = 19/229 (8%)

Query: 47  YDHDAFLGAEEAKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIY 106
           +  + FLG +     +   P  S+ +L +I  K+D + D  ++  E++ WI     ++  
Sbjct: 77  FHQEVFLGKDLGGFDEDAEPRRSRRKLMVIFSKVDVNTDRKISAKEMQRWIMEKTAEHFQ 136

Query: 107 DNVENQWQEF---DMNQDGLISWDEYR------------NVTYGTYLDDPDPDDGFNYKQ 151
           + +E     F   D + DG +SWDEY+             V     L++    D    + 
Sbjct: 137 EAMEESKTHFRAVDPDGDGHVSWDEYKVKFLASKGHSEKEVADAIRLNEELKVDEETQEV 196

Query: 152 MMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLE 211
           +    +R ++      DL+ T+EEF +FLHPE    M   +V+E + D+D++ D  + + 
Sbjct: 197 LENLKDRWYQADSPPADLLLTEEEFLSFLHPEHSRGMLRFMVKEIVRDLDQDGDKQLSVP 256

Query: 212 EYI----GDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKD 256
           E+I    G + +  G   +  WVK  +++F E  D N DG +  EE ++
Sbjct: 257 EFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTAEELEN 305



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 15/96 (15%)

Query: 50  DAFLGAEEAKTFDQLTPEESKERLGMIVDKI----DADKDGFVTEGELKSW----IKHAQ 101
           D  L  EE  +F  L PE S+  L  +V +I    D D D  ++  E  S     +++ Q
Sbjct: 213 DLLLTEEEFLSF--LHPEHSRGMLRFMVKEIVRDLDQDGDKQLSVPEFISLPVGTVENQQ 270

Query: 102 KKYIYDN-VENQWQEF----DMNQDGLISWDEYRNV 132
            + I DN V+++ +EF    D N DG+++ +E  NV
Sbjct: 271 GQDIDDNWVKDRKKEFEELIDSNHDGIVTAEELENV 306


>gi|4885111 calmodulin-like 3 [Homo sapiens]
          Length = 149

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 36/147 (24%), Positives = 69/147 (46%), Gaps = 15/147 (10%)

Query: 150 KQMMVRDERRFKMADKDGDLIATKEEFTAFL-----HPEEYDYMKDIVVQETMEDIDKNA 204
           ++ +   +  F + DKDGD   T  E    +     +P E +      +++ M +ID++ 
Sbjct: 7   EEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAE------LRDMMSEIDRDG 60

Query: 205 DGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYD 264
           +G +D  E++G M     +TD  E +   RE F  F DK+ +G +   E +  +      
Sbjct: 61  NGTVDFPEFLGMMARKMKDTDNEEEI---REAFRVF-DKDGNGFVSAAELRHVMTRLGEK 116

Query: 265 HAEAEARHLVYESDQNKDGKLTKEEIV 291
            ++ E   ++  +D + DG++  EE V
Sbjct: 117 LSDEEVDEMIRAADTDGDGQVNYEEFV 143



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 18/156 (11%)

Query: 62  DQLTPE---ESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDM 118
           DQLT E   E KE   +     D D DG +T  EL + ++   +      + +   E D 
Sbjct: 3   DQLTEEQVTEFKEAFSLF----DKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDR 58

Query: 119 NQDGLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTA 178
           + +G + + E+  +      D  + ++        +R+   F++ DKDG+   +  E   
Sbjct: 59  DGNGTVDFPEFLGMMARKMKDTDNEEE--------IRE--AFRVFDKDGNGFVSAAELRH 108

Query: 179 FLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYI 214
            +     + + D  V E +   D + DG ++ EE++
Sbjct: 109 VM-TRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFV 143



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 4/85 (4%)

Query: 48  DHDAFLGAEEAKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYD 107
           D   FLG    K  D    EE +E   +     D D +GFV+  EL+  +    +K   +
Sbjct: 65  DFPEFLGMMARKMKDTDNEEEIREAFRVF----DKDGNGFVSAAELRHVMTRLGEKLSDE 120

Query: 108 NVENQWQEFDMNQDGLISWDEYRNV 132
            V+   +  D + DG ++++E+  V
Sbjct: 121 EVDEMIRAADTDGDGQVNYEEFVRV 145


>gi|4507617 fast skeletal muscle troponin C [Homo sapiens]
          Length = 160

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 37/144 (25%), Positives = 65/144 (45%), Gaps = 6/144 (4%)

Query: 150 KQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFID 209
           ++M+   +  F M D DG    + +E    +        K+  +   +E++D++  G ID
Sbjct: 14  EEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKE-ELDAIIEEVDEDGSGTID 72

Query: 210 LEEYIGDMYSHDGNTDEPEWVKTEREQFVEFR--DKNRDGKMDKEETKDWILPSDYDHAE 267
            EE++  M        E    K+E E    FR  D+N DG +D EE  +    S     +
Sbjct: 73  FEEFLVMMVRQ---MKEDAKGKSEEELAECFRIFDRNADGYIDPEELAEIFRASGEHVTD 129

Query: 268 AEARHLVYESDQNKDGKLTKEEIV 291
            E   L+ + D+N DG++  +E +
Sbjct: 130 EEIESLMKDGDKNNDGRIDFDEFL 153



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 17/68 (25%), Positives = 33/68 (48%)

Query: 68  ESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMNQDGLISWD 127
           +S+E L       D + DG++   EL    + + +    + +E+  ++ D N DG I +D
Sbjct: 91  KSEEELAECFRIFDRNADGYIDPEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFD 150

Query: 128 EYRNVTYG 135
           E+  +  G
Sbjct: 151 EFLKMMEG 158



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 36/175 (20%), Positives = 62/175 (35%), Gaps = 53/175 (30%)

Query: 45  FDYDHDAFLGAEEAKTFDQLTPEE-SKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKK 103
           FD D    +  +E  T  ++  +  +KE L  I++++D D  G +   E    +    K+
Sbjct: 27  FDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKE 86

Query: 104 YIYDNVENQWQE----FDMNQDGLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERR 159
                 E +  E    FD N DG I                 DP++              
Sbjct: 87  DAKGKSEEELAECFRIFDRNADGYI-----------------DPEE-------------- 115

Query: 160 FKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYI 214
                             A +     +++ D  ++  M+D DKN DG ID +E++
Sbjct: 116 -----------------LAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFL 153


>gi|58218968 calmodulin 3 [Homo sapiens]
          Length = 149

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 39/147 (26%), Positives = 69/147 (46%), Gaps = 15/147 (10%)

Query: 150 KQMMVRDERRFKMADKDGD-LIATKEEFTAFL----HPEEYDYMKDIVVQETMEDIDKNA 204
           ++ +   +  F + DKDGD  I TKE  T       +P E +      +Q+ + ++D + 
Sbjct: 7   EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAE------LQDMINEVDADG 60

Query: 205 DGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYD 264
           +G ID  E++  M     +TD  E +   RE F  F DK+ +G +   E +  +      
Sbjct: 61  NGTIDFPEFLTMMARKMKDTDSEEEI---REAFRVF-DKDGNGYISAAELRHVMTNLGEK 116

Query: 265 HAEAEARHLVYESDQNKDGKLTKEEIV 291
             + E   ++ E+D + DG++  EE V
Sbjct: 117 LTDEEVDEMIREADIDGDGQVNYEEFV 143



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 6/101 (5%)

Query: 31  EPQLSDKVHN-DAQ-SFDYDHDAFLGAEEAKTFDQLTPEESKERLGMIVDKIDADKDGFV 88
           E +L D ++  DA  +   D   FL     K  D  + EE +E   +     D D +G++
Sbjct: 46  EAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVF----DKDGNGYI 101

Query: 89  TEGELKSWIKHAQKKYIYDNVENQWQEFDMNQDGLISWDEY 129
           +  EL+  + +  +K   + V+   +E D++ DG ++++E+
Sbjct: 102 SAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 142


>gi|4502549 calmodulin 2 [Homo sapiens]
          Length = 149

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 39/147 (26%), Positives = 69/147 (46%), Gaps = 15/147 (10%)

Query: 150 KQMMVRDERRFKMADKDGD-LIATKEEFTAFL----HPEEYDYMKDIVVQETMEDIDKNA 204
           ++ +   +  F + DKDGD  I TKE  T       +P E +      +Q+ + ++D + 
Sbjct: 7   EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAE------LQDMINEVDADG 60

Query: 205 DGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYD 264
           +G ID  E++  M     +TD  E +   RE F  F DK+ +G +   E +  +      
Sbjct: 61  NGTIDFPEFLTMMARKMKDTDSEEEI---REAFRVF-DKDGNGYISAAELRHVMTNLGEK 116

Query: 265 HAEAEARHLVYESDQNKDGKLTKEEIV 291
             + E   ++ E+D + DG++  EE V
Sbjct: 117 LTDEEVDEMIREADIDGDGQVNYEEFV 143



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 6/101 (5%)

Query: 31  EPQLSDKVHN-DAQ-SFDYDHDAFLGAEEAKTFDQLTPEESKERLGMIVDKIDADKDGFV 88
           E +L D ++  DA  +   D   FL     K  D  + EE +E   +     D D +G++
Sbjct: 46  EAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVF----DKDGNGYI 101

Query: 89  TEGELKSWIKHAQKKYIYDNVENQWQEFDMNQDGLISWDEY 129
           +  EL+  + +  +K   + V+   +E D++ DG ++++E+
Sbjct: 102 SAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 142


>gi|5901912 calmodulin 1 [Homo sapiens]
          Length = 149

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 39/147 (26%), Positives = 69/147 (46%), Gaps = 15/147 (10%)

Query: 150 KQMMVRDERRFKMADKDGD-LIATKEEFTAFL----HPEEYDYMKDIVVQETMEDIDKNA 204
           ++ +   +  F + DKDGD  I TKE  T       +P E +      +Q+ + ++D + 
Sbjct: 7   EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAE------LQDMINEVDADG 60

Query: 205 DGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYD 264
           +G ID  E++  M     +TD  E +   RE F  F DK+ +G +   E +  +      
Sbjct: 61  NGTIDFPEFLTMMARKMKDTDSEEEI---REAFRVF-DKDGNGYISAAELRHVMTNLGEK 116

Query: 265 HAEAEARHLVYESDQNKDGKLTKEEIV 291
             + E   ++ E+D + DG++  EE V
Sbjct: 117 LTDEEVDEMIREADIDGDGQVNYEEFV 143



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 6/101 (5%)

Query: 31  EPQLSDKVHN-DAQ-SFDYDHDAFLGAEEAKTFDQLTPEESKERLGMIVDKIDADKDGFV 88
           E +L D ++  DA  +   D   FL     K  D  + EE +E   +     D D +G++
Sbjct: 46  EAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVF----DKDGNGYI 101

Query: 89  TEGELKSWIKHAQKKYIYDNVENQWQEFDMNQDGLISWDEY 129
           +  EL+  + +  +K   + V+   +E D++ DG ++++E+
Sbjct: 102 SAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 142


>gi|4507615 troponin C, slow [Homo sapiens]
          Length = 161

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 5/102 (4%)

Query: 193 VQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFR--DKNRDGKMD 250
           +QE ++++D++  G +D +E++  M     +  +    K+E E    FR  DKN DG +D
Sbjct: 57  LQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKG---KSEEELSDLFRMFDKNADGYID 113

Query: 251 KEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVD 292
            +E K  +  +     E +   L+ + D+N DG++  +E ++
Sbjct: 114 LDELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLE 155



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 2/97 (2%)

Query: 33  QLSDKVHNDAQSFDYDHDAFLGAEEAKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGE 92
           ++ D+V  D  S   D D FL     +     +  +S+E L  +    D + DG++   E
Sbjct: 59  EMIDEVDEDG-SGTVDFDEFL-VMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDE 116

Query: 93  LKSWIKHAQKKYIYDNVENQWQEFDMNQDGLISWDEY 129
           LK  ++   +    D++E   ++ D N DG I +DE+
Sbjct: 117 LKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEF 153



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 44/195 (22%), Positives = 71/195 (36%), Gaps = 64/195 (32%)

Query: 33  QLSDKVHNDAQSFDYDHDAF-LGAEEA--------KTFDQLTPEESKERLGMIVDKIDAD 83
           QL+++  N+   F    D F LGAE+         K    L    + E L  ++D++D D
Sbjct: 11  QLTEEQKNE---FKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDED 67

Query: 84  KDGFVTEGE----LKSWIKHAQKKYIYDNVENQWQEFDMNQDGLISWDEYRNVTYGTYLD 139
             G V   E    +   +K   K    + + + ++ FD N DG I  DE + +   T   
Sbjct: 68  GSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIMLQAT--- 124

Query: 140 DPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMED 199
                                      G+ I   +                  ++E M+D
Sbjct: 125 ---------------------------GETITEDD------------------IEELMKD 139

Query: 200 IDKNADGFIDLEEYI 214
            DKN DG ID +E++
Sbjct: 140 GDKNNDGRIDYDEFL 154


>gi|215983090 guanylate cyclase activator 1C [Homo sapiens]
          Length = 209

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 36/141 (25%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 158 RRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDM 217
           R F M    G  + T  EF   L  +  +   +  + +     D N DGF+D  E+I  +
Sbjct: 24  RTFMMEYPSG--LQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81

Query: 218 YSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWI-----LPSDYDHAEAEARH 272
                N    E ++ + + + +  D + +G +DK E  D       L      +  E  +
Sbjct: 82  -----NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136

Query: 273 LVYES-DQNKDGKLTKEEIVD 292
           LV+   D N DG+LT EE ++
Sbjct: 137 LVFHKIDINNDGELTLEEFIN 157



 Score = 28.5 bits (62), Expect = 8.1
 Identities = 28/122 (22%), Positives = 47/122 (38%), Gaps = 30/122 (24%)

Query: 108 NVENQWQEFDMNQDGLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDG 167
           +++  +  FD N+DG + + E+               +    ++M  + +  FK+ D DG
Sbjct: 56  HIDQVYNTFDTNKDGFVDFLEFIAAV-----------NLIMQEKMEQKLKWYFKLYDADG 104

Query: 168 DLIATKEEFTAF------------LHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIG 215
           +    K E                L PEE+       +      ID N DG + LEE+I 
Sbjct: 105 NGSIDKNELLDMFMAVQALNGQQTLSPEEF-------INLVFHKIDINNDGELTLEEFIN 157

Query: 216 DM 217
            M
Sbjct: 158 GM 159


>gi|13929432 calcium binding protein 1 isoform 1 [Homo sapiens]
          Length = 227

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 38/160 (23%), Positives = 70/160 (43%), Gaps = 7/160 (4%)

Query: 55  AEEAKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQ 114
           AE  +    L PEE +E L     + D DKDG++   +L + ++          +    Q
Sbjct: 70  AENRQPDRSLRPEEIEE-LREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQ 128

Query: 115 EFDMNQDGLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKE 174
           + +MN  G + +D++  +     L   +  D    K++  RD   F+  D +GD   +  
Sbjct: 129 QINMNLGGHVDFDDFVELMGPKLL--AETADMIGVKEL--RD--AFREFDTNGDGEISTS 182

Query: 175 EFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYI 214
           E    +       +    ++E + D+D N DG +D EE++
Sbjct: 183 ELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFV 222


>gi|110835715 calcyphosine-like [Homo sapiens]
          Length = 208

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 7/98 (7%)

Query: 157 ERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGD 216
           E  F+  DKDG+      EF   L P      K++++Q     +DK  DG I +E+ + +
Sbjct: 81  EELFRRFDKDGNGTIDFNEFLLTLRPPMSRARKEVIMQ-AFRKLDKTGDGVITIED-LRE 138

Query: 217 MYS--HDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKE 252
           +Y+  H       EW  +E + F +F D N D   DK+
Sbjct: 139 VYNAKHHPKYQNGEW--SEEQVFRKFLD-NFDSPYDKD 173



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 41/162 (25%), Positives = 68/162 (41%), Gaps = 27/162 (16%)

Query: 158 RRFKMADKDGDLIATKEEFTAFLHPEEYDY---MKDIVVQETMEDIDKNADGFIDLEEYI 214
           R F++ D D +     +EF   L+    DY   M+   V+E     DK+ +G ID  E++
Sbjct: 46  RVFRIMDDDNNRTLDFKEFMKGLN----DYAVVMEKEEVEELFRRFDKDGNGTIDFNEFL 101

Query: 215 GDMYSHDGNTDEPEWVKTEREQFVE-FR--DKNRDGKMDKEETKDWILPS---DYDHAEA 268
                    T  P   +  +E  ++ FR  DK  DG +  E+ ++         Y + E 
Sbjct: 102 --------LTLRPPMSRARKEVIMQAFRKLDKTGDGVITIEDLREVYNAKHHPKYQNGEW 153

Query: 269 EARHLV------YESDQNKDGKLTKEEIVDKYDLFVGSQATD 304
               +       ++S  +KDG +T EE ++ Y     S  TD
Sbjct: 154 SEEQVFRKFLDNFDSPYDKDGLVTPEEFMNYYAGVSASIDTD 195


>gi|110835717 calcyphosine-like [Homo sapiens]
          Length = 208

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 7/98 (7%)

Query: 157 ERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGD 216
           E  F+  DKDG+      EF   L P      K++++Q     +DK  DG I +E+ + +
Sbjct: 81  EELFRRFDKDGNGTIDFNEFLLTLRPPMSRARKEVIMQ-AFRKLDKTGDGVITIED-LRE 138

Query: 217 MYS--HDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKE 252
           +Y+  H       EW  +E + F +F D N D   DK+
Sbjct: 139 VYNAKHHPKYQNGEW--SEEQVFRKFLD-NFDSPYDKD 173



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 41/162 (25%), Positives = 68/162 (41%), Gaps = 27/162 (16%)

Query: 158 RRFKMADKDGDLIATKEEFTAFLHPEEYDY---MKDIVVQETMEDIDKNADGFIDLEEYI 214
           R F++ D D +     +EF   L+    DY   M+   V+E     DK+ +G ID  E++
Sbjct: 46  RVFRIMDDDNNRTLDFKEFMKGLN----DYAVVMEKEEVEELFRRFDKDGNGTIDFNEFL 101

Query: 215 GDMYSHDGNTDEPEWVKTEREQFVE-FR--DKNRDGKMDKEETKDWILPS---DYDHAEA 268
                    T  P   +  +E  ++ FR  DK  DG +  E+ ++         Y + E 
Sbjct: 102 --------LTLRPPMSRARKEVIMQAFRKLDKTGDGVITIEDLREVYNAKHHPKYQNGEW 153

Query: 269 EARHLV------YESDQNKDGKLTKEEIVDKYDLFVGSQATD 304
               +       ++S  +KDG +T EE ++ Y     S  TD
Sbjct: 154 SEEQVFRKFLDNFDSPYDKDGLVTPEEFMNYYAGVSASIDTD 195


>gi|76056882 calcium binding protein 1 isoform 3 [Homo sapiens]
          Length = 370

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 36/151 (23%), Positives = 67/151 (44%), Gaps = 7/151 (4%)

Query: 64  LTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMNQDGL 123
           L PEE +E L     + D DKDG++   +L + ++          +    Q+ +MN  G 
Sbjct: 222 LRPEEIEE-LREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGH 280

Query: 124 ISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPE 183
           + +D++  +     L   +  D    K++  RD   F+  D +GD   +  E    +   
Sbjct: 281 VDFDDFVELMGPKLL--AETADMIGVKEL--RDA--FREFDTNGDGEISTSELREAMRKL 334

Query: 184 EYDYMKDIVVQETMEDIDKNADGFIDLEEYI 214
               +    ++E + D+D N DG +D EE++
Sbjct: 335 LGHQVGHRDIEEIIRDVDLNGDGRVDFEEFV 365


>gi|13929434 calcium binding protein 1 isoform 2 [Homo sapiens]
          Length = 167

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 36/151 (23%), Positives = 67/151 (44%), Gaps = 7/151 (4%)

Query: 64  LTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMNQDGL 123
           L PEE +E L     + D DKDG++   +L + ++          +    Q+ +MN  G 
Sbjct: 19  LRPEEIEE-LREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGH 77

Query: 124 ISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPE 183
           + +D++  +     L   +  D    K++  RD   F+  D +GD   +  E    +   
Sbjct: 78  VDFDDFVELMGPKLL--AETADMIGVKEL--RDA--FREFDTNGDGEISTSELREAMRKL 131

Query: 184 EYDYMKDIVVQETMEDIDKNADGFIDLEEYI 214
               +    ++E + D+D N DG +D EE++
Sbjct: 132 LGHQVGHRDIEEIIRDVDLNGDGRVDFEEFV 162


>gi|78190488 Kv channel interacting protein 4 isoform 3 [Homo
           sapiens]
          Length = 188

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 23/104 (22%)

Query: 44  SFDYDHDAFLGAEE-AKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQK 102
           +FD DH+  +  E+  K    L     +E+L    +  D +KDG++T+ E+   +K    
Sbjct: 69  AFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKA--- 125

Query: 103 KYIYD-----------------NVENQWQEFDMNQDGLISWDEY 129
             IYD                 +VE  +Q+ D N+DG+++ DE+
Sbjct: 126 --IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEF 167


>gi|78190486 Kv channel interacting protein 4 isoform 5 [Homo
           sapiens]
          Length = 225

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 23/104 (22%)

Query: 44  SFDYDHDAFLGAEE-AKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQK 102
           +FD DH+  +  E+  K    L     +E+L    +  D +KDG++T+ E+   +K    
Sbjct: 106 AFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKA--- 162

Query: 103 KYIYD-----------------NVENQWQEFDMNQDGLISWDEY 129
             IYD                 +VE  +Q+ D N+DG+++ DE+
Sbjct: 163 --IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEF 204


>gi|22212902 Kv channel interacting protein 4 isoform 4 [Homo
           sapiens]
          Length = 229

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 23/104 (22%)

Query: 44  SFDYDHDAFLGAEE-AKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQK 102
           +FD DH+  +  E+  K    L     +E+L    +  D +KDG++T+ E+   +K    
Sbjct: 110 AFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKA--- 166

Query: 103 KYIYD-----------------NVENQWQEFDMNQDGLISWDEY 129
             IYD                 +VE  +Q+ D N+DG+++ DE+
Sbjct: 167 --IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEF 208


>gi|22212900 Kv channel interacting protein 4 isoform 3 [Homo
           sapiens]
          Length = 188

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 23/104 (22%)

Query: 44  SFDYDHDAFLGAEE-AKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQK 102
           +FD DH+  +  E+  K    L     +E+L    +  D +KDG++T+ E+   +K    
Sbjct: 69  AFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKA--- 125

Query: 103 KYIYD-----------------NVENQWQEFDMNQDGLISWDEY 129
             IYD                 +VE  +Q+ D N+DG+++ DE+
Sbjct: 126 --IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEF 167


>gi|22212898 Kv channel interacting protein 4 isoform 2 [Homo
           sapiens]
          Length = 216

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 23/104 (22%)

Query: 44  SFDYDHDAFLGAEE-AKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQK 102
           +FD DH+  +  E+  K    L     +E+L    +  D +KDG++T+ E+   +K    
Sbjct: 97  AFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKA--- 153

Query: 103 KYIYD-----------------NVENQWQEFDMNQDGLISWDEY 129
             IYD                 +VE  +Q+ D N+DG+++ DE+
Sbjct: 154 --IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEF 195


>gi|24586671 Kv channel interacting protein 4 isoform 1 [Homo
           sapiens]
          Length = 250

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 23/104 (22%)

Query: 44  SFDYDHDAFLGAEE-AKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQK 102
           +FD DH+  +  E+  K    L     +E+L    +  D +KDG++T+ E+   +K    
Sbjct: 131 AFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKA--- 187

Query: 103 KYIYD-----------------NVENQWQEFDMNQDGLISWDEY 129
             IYD                 +VE  +Q+ D N+DG+++ DE+
Sbjct: 188 --IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEF 229


>gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
            isoform 2 [Homo sapiens]
          Length = 2472

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 32/102 (31%), Positives = 45/102 (44%), Gaps = 13/102 (12%)

Query: 160  FKMADKDGDLIATKEEFTAFLHPEEYDYMK------DIVVQETMEDIDKNADGFIDLEEY 213
            FK  DKD       +EF + L    YD         D   +  ++ +D N DG + L+EY
Sbjct: 2332 FKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEY 2391

Query: 214  IGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGK--MDKEE 253
            +  M S      E E VK+  E    FR  + +GK  + KEE
Sbjct: 2392 MAFMISR-----ETENVKSSEEIESAFRALSSEGKPYVTKEE 2428



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 29/128 (22%), Positives = 45/128 (35%), Gaps = 16/128 (12%)

Query: 67   EESKERLGMIVDKIDADKDGFVTEGELKSWIKH-------AQKKYIYDNVENQWQEFDMN 119
            EE+ +   M+    D DK G +   E KS ++         ++       E      D N
Sbjct: 2322 EEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPN 2381

Query: 120  QDGLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAF 179
            +DG +S  EY         ++    +           E  F+    +G    TKEE    
Sbjct: 2382 RDGHVSLQEYMAFMISRETENVKSSEEI---------ESAFRALSSEGKPYVTKEELYQN 2432

Query: 180  LHPEEYDY 187
            L  E+ DY
Sbjct: 2433 LTREQADY 2440


>gi|194595509 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
            isoform 1 [Homo sapiens]
          Length = 2477

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 32/102 (31%), Positives = 45/102 (44%), Gaps = 13/102 (12%)

Query: 160  FKMADKDGDLIATKEEFTAFLHPEEYDYMK------DIVVQETMEDIDKNADGFIDLEEY 213
            FK  DKD       +EF + L    YD         D   +  ++ +D N DG + L+EY
Sbjct: 2337 FKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEY 2396

Query: 214  IGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGK--MDKEE 253
            +  M S      E E VK+  E    FR  + +GK  + KEE
Sbjct: 2397 MAFMISR-----ETENVKSSEEIESAFRALSSEGKPYVTKEE 2433



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 29/128 (22%), Positives = 45/128 (35%), Gaps = 16/128 (12%)

Query: 67   EESKERLGMIVDKIDADKDGFVTEGELKSWIKH-------AQKKYIYDNVENQWQEFDMN 119
            EE+ +   M+    D DK G +   E KS ++         ++       E      D N
Sbjct: 2327 EEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPN 2386

Query: 120  QDGLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAF 179
            +DG +S  EY         ++    +           E  F+    +G    TKEE    
Sbjct: 2387 RDGHVSLQEYMAFMISRETENVKSSEEI---------ESAFRALSSEGKPYVTKEELYQN 2437

Query: 180  LHPEEYDY 187
            L  E+ DY
Sbjct: 2438 LTREQADY 2445


>gi|110611180 calcium binding protein 2 isoform 2 [Homo sapiens]
          Length = 163

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 14/154 (9%)

Query: 63  QLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMN-QD 121
           +L PEE +E L +   + D D+DG++   EL + ++       Y   E +  E       
Sbjct: 17  ELRPEEIEE-LQVAFQEFDRDRDGYIGCRELGACMRTLG----YMPTEMELIEISQQISG 71

Query: 122 GLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDER-RFKMADKDGDLIATKEEFTAFL 180
           G + ++++  +     L +     G       VR+ R  F+  D +GD   +  E  A L
Sbjct: 72  GKVDFEDFVELMGPKLLAETADMIG-------VRELRDAFREFDTNGDGRISVGELRAAL 124

Query: 181 HPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYI 214
                + +    V E ++D+D N DG +D EE++
Sbjct: 125 KALLGERLSQREVDEILQDVDLNGDGLVDFEEFV 158



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 19/73 (26%), Positives = 39/73 (53%), Gaps = 5/73 (6%)

Query: 58  AKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDN-VENQWQEF 116
           A+T D +   E ++       + D + DG ++ GEL++ +K    + +    V+   Q+ 
Sbjct: 89  AETADMIGVRELRDAFR----EFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDV 144

Query: 117 DMNQDGLISWDEY 129
           D+N DGL+ ++E+
Sbjct: 145 DLNGDGLVDFEEF 157


>gi|110611178 calcium binding protein 2 isoform 1 [Homo sapiens]
          Length = 220

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 14/154 (9%)

Query: 63  QLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMN-QD 121
           +L PEE +E L +   + D D+DG++   EL + ++       Y   E +  E       
Sbjct: 74  ELRPEEIEE-LQVAFQEFDRDRDGYIGCRELGACMRTLG----YMPTEMELIEISQQISG 128

Query: 122 GLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDER-RFKMADKDGDLIATKEEFTAFL 180
           G + ++++  +     L +     G       VR+ R  F+  D +GD   +  E  A L
Sbjct: 129 GKVDFEDFVELMGPKLLAETADMIG-------VRELRDAFREFDTNGDGRISVGELRAAL 181

Query: 181 HPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYI 214
                + +    V E ++D+D N DG +D EE++
Sbjct: 182 KALLGERLSQREVDEILQDVDLNGDGLVDFEEFV 215



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 19/73 (26%), Positives = 39/73 (53%), Gaps = 5/73 (6%)

Query: 58  AKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDN-VENQWQEF 116
           A+T D +   E ++       + D + DG ++ GEL++ +K    + +    V+   Q+ 
Sbjct: 146 AETADMIGVRELRDAFR----EFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDV 201

Query: 117 DMNQDGLISWDEY 129
           D+N DGL+ ++E+
Sbjct: 202 DLNGDGLVDFEEF 214


>gi|15055537 secretagogin precursor [Homo sapiens]
          Length = 276

 Score = 36.6 bits (83), Expect = 0.030
 Identities = 51/257 (19%), Positives = 94/257 (36%), Gaps = 50/257 (19%)

Query: 79  KIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMNQDGLISWDEYRNVTYGTYL 138
           + DAD+ G++ E EL ++  H   K   D+   +     + Q  + + D  +        
Sbjct: 23  RFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKANLHKVKQQFMTTQDASK-------- 74

Query: 139 DDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETME 198
                 DG            R +M +  G  ++  E F   L   E      +   +   
Sbjct: 75  ------DG------------RIRMKELAGMFLSEDENF-LLLFRRENPLDSSVEFMQIWR 115

Query: 199 DIDKNADGFI---DLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEE-- 253
             D ++ GFI   +L  ++ D++ H         ++      ++  D+N+DG++D  +  
Sbjct: 116 KYDADSSGFISAAELRNFLRDLFLHHKKAISEAKLEEYTGTMMKIFDRNKDGRLDLNDLA 175

Query: 254 -----TKDWILPSDYDHAEAEARHLVYES-----DQNKDGKLTKEE----IVDKYDL--- 296
                 ++++L    D    E R   +E      D +K G L   E    + D  +L   
Sbjct: 176 RILALQENFLLQFKMDACSTEERKRDFEKIFAYYDVSKTGALEGPEVDGFVKDMMELVQP 235

Query: 297 -FVGSQATDFGEALVRH 312
              G     F E L+RH
Sbjct: 236 SISGVDLDKFREILLRH 252



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 8/80 (10%)

Query: 61  FDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIK----HAQKKYIYDNVE----NQ 112
           F +  P +S      I  K DAD  GF++  EL+++++    H +K      +E      
Sbjct: 98  FRRENPLDSSVEFMQIWRKYDADSSGFISAAELRNFLRDLFLHHKKAISEAKLEEYTGTM 157

Query: 113 WQEFDMNQDGLISWDEYRNV 132
            + FD N+DG +  ++   +
Sbjct: 158 MKIFDRNKDGRLDLNDLARI 177


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,643,054
Number of Sequences: 37866
Number of extensions: 592639
Number of successful extensions: 1996
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 104
Number of HSP's that attempted gapping in prelim test: 1536
Number of HSP's gapped (non-prelim): 413
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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