Search of human proteins with 194363771

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194363771 sperm specific antigen 2 isoform 1 [Homo sapiens]
         (1259 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194363771 sperm specific antigen 2 isoform 1 [Homo sapiens]       2469   0.0  
gi|28557788 sperm specific antigen 2 isoform 2 [Homo sapiens]        2409   0.0  
gi|209862861 hypothetical protein LOC9840 [Homo sapiens]              147   6e-35
gi|149363704 hypothetical protein LOC9840 [Homo sapiens]              147   6e-35
gi|154937346 coiled-coil domain containing 129 [Homo sapiens]         124   6e-28
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    57   1e-07
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po...    52   4e-06
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        50   1e-05
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    50   2e-05
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    50   2e-05
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        48   7e-05
gi|91982772 mucin 17 [Homo sapiens]                                    48   7e-05
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    45   4e-04
gi|28373194 adhesion regulating molecule 1 precursor [Homo sapiens]    45   6e-04
gi|28373192 adhesion regulating molecule 1 precursor [Homo sapiens]    45   6e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         45   6e-04
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    44   0.001
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    44   0.001
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun...    44   0.001
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun...    44   0.001
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit...    44   0.001
gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]                 42   0.003
gi|109637767 calpastatin isoform j [Homo sapiens]                      42   0.003
gi|109637765 calpastatin isoform i [Homo sapiens]                      42   0.003
gi|109637763 calpastatin isoform h [Homo sapiens]                      42   0.003
gi|109637761 calpastatin isoform g [Homo sapiens]                      42   0.003
gi|109637759 calpastatin isoform f [Homo sapiens]                      42   0.003
gi|27765085 calpastatin isoform b [Homo sapiens]                       42   0.003
gi|109637753 calpastatin isoform a [Homo sapiens]                      42   0.003
gi|118498337 HECT domain containing 1 [Homo sapiens]                   42   0.003

>gi|194363771 sperm specific antigen 2 isoform 1 [Homo sapiens]
          Length = 1259

 Score = 2469 bits (6400), Expect = 0.0
 Identities = 1259/1259 (100%), Positives = 1259/1259 (100%)

Query: 1    MDRPLSSSAEAEEELEWQVASRRRKAWAKCRSSWQASETEDLSTEATTQDEEEDEEEDLP 60
            MDRPLSSSAEAEEELEWQVASRRRKAWAKCRSSWQASETEDLSTEATTQDEEEDEEEDLP
Sbjct: 1    MDRPLSSSAEAEEELEWQVASRRRKAWAKCRSSWQASETEDLSTEATTQDEEEDEEEDLP 60

Query: 61   GAQLPAAGGRGNVPNEKIAIWLKDCRTPLGASLDEQSSSTLKGVLVRNGGSFEDDLSLGA 120
            GAQLPAAGGRGNVPNEKIAIWLKDCRTPLGASLDEQSSSTLKGVLVRNGGSFEDDLSLGA
Sbjct: 61   GAQLPAAGGRGNVPNEKIAIWLKDCRTPLGASLDEQSSSTLKGVLVRNGGSFEDDLSLGA 120

Query: 121  EANHLHESDAQIENCNNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDP 180
            EANHLHESDAQIENCNNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDP
Sbjct: 121  EANHLHESDAQIENCNNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDP 180

Query: 181  EEILYNLGFGRDEPDIASKIPSRFFNSSSFAKGIDIKVFLSAQMQRMEVENPNYALTSRF 240
            EEILYNLGFGRDEPDIASKIPSRFFNSSSFAKGIDIKVFLSAQMQRMEVENPNYALTSRF
Sbjct: 181  EEILYNLGFGRDEPDIASKIPSRFFNSSSFAKGIDIKVFLSAQMQRMEVENPNYALTSRF 240

Query: 241  RQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSNKETDPPPPLTRSNTANRLMKTLS 300
            RQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSNKETDPPPPLTRSNTANRLMKTLS
Sbjct: 241  RQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSNKETDPPPPLTRSNTANRLMKTLS 300

Query: 301  KLNLCVDKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVK 360
            KLNLCVDKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVK
Sbjct: 301  KLNLCVDKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVK 360

Query: 361  EEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSD 420
            EEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSD
Sbjct: 361  EEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSD 420

Query: 421  FNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAP 480
            FNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAP
Sbjct: 421  FNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAP 480

Query: 481  HVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSC 540
            HVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSC
Sbjct: 481  HVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSC 540

Query: 541  DSETTVTSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCN 600
            DSETTVTSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCN
Sbjct: 541  DSETTVTSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCN 600

Query: 601  TIENTGTKQSTCSPGDHIIEITEVEEDLFPAETVELLREASAESDVGKSSESEFTQYTTH 660
            TIENTGTKQSTCSPGDHIIEITEVEEDLFPAETVELLREASAESDVGKSSESEFTQYTTH
Sbjct: 601  TIENTGTKQSTCSPGDHIIEITEVEEDLFPAETVELLREASAESDVGKSSESEFTQYTTH 660

Query: 661  HILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDL 720
            HILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDL
Sbjct: 661  HILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDL 720

Query: 721  LKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEE 780
            LKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEE
Sbjct: 721  LKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEE 780

Query: 781  QELEKRVMEHDGQSLVKSTIFISPSSVKKEEAPQSEAPRVEECHHGRTPTCSRLAPPPMS 840
            QELEKRVMEHDGQSLVKSTIFISPSSVKKEEAPQSEAPRVEECHHGRTPTCSRLAPPPMS
Sbjct: 781  QELEKRVMEHDGQSLVKSTIFISPSSVKKEEAPQSEAPRVEECHHGRTPTCSRLAPPPMS 840

Query: 841  QSTCSLHSIHSEWQERPLCEHTRTLSTHSVPNISGATCSAFASPFGCPYSHRHATYPYRV 900
            QSTCSLHSIHSEWQERPLCEHTRTLSTHSVPNISGATCSAFASPFGCPYSHRHATYPYRV
Sbjct: 841  QSTCSLHSIHSEWQERPLCEHTRTLSTHSVPNISGATCSAFASPFGCPYSHRHATYPYRV 900

Query: 901  CSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDPAAAPYSTQKSSVLPLYENTFQE 960
            CSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDPAAAPYSTQKSSVLPLYENTFQE
Sbjct: 901  CSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDPAAAPYSTQKSSVLPLYENTFQE 960

Query: 961  LQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERFEVDQLQGLRNSVRMELQDLEL 1020
            LQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERFEVDQLQGLRNSVRMELQDLEL
Sbjct: 961  LQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERFEVDQLQGLRNSVRMELQDLEL 1020

Query: 1021 QLEERLLGLEEQLRAVRMPSPFRSSALMGMCGSRSADNLSCPSPLNVMEPVTELMQEQSY 1080
            QLEERLLGLEEQLRAVRMPSPFRSSALMGMCGSRSADNLSCPSPLNVMEPVTELMQEQSY
Sbjct: 1021 QLEERLLGLEEQLRAVRMPSPFRSSALMGMCGSRSADNLSCPSPLNVMEPVTELMQEQSY 1080

Query: 1081 LKSELGLGLGEMGFEIPPGESSESVFSQATSESSSVCSGPSHANRRTGVPSTASVGKSKT 1140
            LKSELGLGLGEMGFEIPPGESSESVFSQATSESSSVCSGPSHANRRTGVPSTASVGKSKT
Sbjct: 1081 LKSELGLGLGEMGFEIPPGESSESVFSQATSESSSVCSGPSHANRRTGVPSTASVGKSKT 1140

Query: 1141 PLVARKKVFRASVALTPTAPSRTGSVQTPPDLESSEEVDAAEGAPEVVGPKSEVEEGHGK 1200
            PLVARKKVFRASVALTPTAPSRTGSVQTPPDLESSEEVDAAEGAPEVVGPKSEVEEGHGK
Sbjct: 1141 PLVARKKVFRASVALTPTAPSRTGSVQTPPDLESSEEVDAAEGAPEVVGPKSEVEEGHGK 1200

Query: 1201 LPSMPAAEEMHKNVEQDELQQVIREIKESIVGEIRREIVSGLLAAVSSSKASNSKQDYH 1259
            LPSMPAAEEMHKNVEQDELQQVIREIKESIVGEIRREIVSGLLAAVSSSKASNSKQDYH
Sbjct: 1201 LPSMPAAEEMHKNVEQDELQQVIREIKESIVGEIRREIVSGLLAAVSSSKASNSKQDYH 1259


>gi|28557788 sperm specific antigen 2 isoform 2 [Homo sapiens]
          Length = 1256

 Score = 2409 bits (6243), Expect = 0.0
 Identities = 1225/1226 (99%), Positives = 1226/1226 (100%)

Query: 1    MDRPLSSSAEAEEELEWQVASRRRKAWAKCRSSWQASETEDLSTEATTQDEEEDEEEDLP 60
            MDRPLSSSAEAEEELEWQVASRRRKAWAKCRSSWQASETEDLSTEATTQDEEEDEEEDLP
Sbjct: 1    MDRPLSSSAEAEEELEWQVASRRRKAWAKCRSSWQASETEDLSTEATTQDEEEDEEEDLP 60

Query: 61   GAQLPAAGGRGNVPNEKIAIWLKDCRTPLGASLDEQSSSTLKGVLVRNGGSFEDDLSLGA 120
            GAQLPAAGGRGNVPNEKIAIWLKDCRTPLGASLDEQSSSTLKGVLVRNGGSFEDDLSLGA
Sbjct: 61   GAQLPAAGGRGNVPNEKIAIWLKDCRTPLGASLDEQSSSTLKGVLVRNGGSFEDDLSLGA 120

Query: 121  EANHLHESDAQIENCNNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDP 180
            EANHLHESDAQIENCNNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDP
Sbjct: 121  EANHLHESDAQIENCNNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDP 180

Query: 181  EEILYNLGFGRDEPDIASKIPSRFFNSSSFAKGIDIKVFLSAQMQRMEVENPNYALTSRF 240
            EEILYNLGFGRDEPDIASKIPSRFFNSSSFAKGIDIKVFLSAQMQRMEVENPNYALTSRF
Sbjct: 181  EEILYNLGFGRDEPDIASKIPSRFFNSSSFAKGIDIKVFLSAQMQRMEVENPNYALTSRF 240

Query: 241  RQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSNKETDPPPPLTRSNTANRLMKTLS 300
            RQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSNKETDPPPPLTRSNTANRLMKTLS
Sbjct: 241  RQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSNKETDPPPPLTRSNTANRLMKTLS 300

Query: 301  KLNLCVDKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVK 360
            KLNLCVDKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVK
Sbjct: 301  KLNLCVDKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVK 360

Query: 361  EEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSD 420
            EEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSD
Sbjct: 361  EEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSD 420

Query: 421  FNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAP 480
            FNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAP
Sbjct: 421  FNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAP 480

Query: 481  HVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSC 540
            HVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSC
Sbjct: 481  HVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSC 540

Query: 541  DSETTVTSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCN 600
            DSETTVTSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCN
Sbjct: 541  DSETTVTSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCN 600

Query: 601  TIENTGTKQSTCSPGDHIIEITEVEEDLFPAETVELLREASAESDVGKSSESEFTQYTTH 660
            TIENTGTKQSTCSPGDHIIEITEVEEDLFPAETVELLREASAESDVGKSSESEFTQYTTH
Sbjct: 601  TIENTGTKQSTCSPGDHIIEITEVEEDLFPAETVELLREASAESDVGKSSESEFTQYTTH 660

Query: 661  HILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDL 720
            HILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDL
Sbjct: 661  HILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDL 720

Query: 721  LKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEE 780
            LKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEE
Sbjct: 721  LKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEE 780

Query: 781  QELEKRVMEHDGQSLVKSTIFISPSSVKKEEAPQSEAPRVEECHHGRTPTCSRLAPPPMS 840
            QELEKRVMEHDGQSLVKSTIFISPSSVKKEEAPQSEAPRVEECHHGRTPTCSRLAPPPMS
Sbjct: 781  QELEKRVMEHDGQSLVKSTIFISPSSVKKEEAPQSEAPRVEECHHGRTPTCSRLAPPPMS 840

Query: 841  QSTCSLHSIHSEWQERPLCEHTRTLSTHSVPNISGATCSAFASPFGCPYSHRHATYPYRV 900
            QSTCSLHSIHSEWQERPLCEHTRTLSTHSVPNISGATCSAFASPFGCPYSHRHATYPYRV
Sbjct: 841  QSTCSLHSIHSEWQERPLCEHTRTLSTHSVPNISGATCSAFASPFGCPYSHRHATYPYRV 900

Query: 901  CSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDPAAAPYSTQKSSVLPLYENTFQE 960
            CSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDPAAAPYSTQKSSVLPLYENTFQE
Sbjct: 901  CSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDPAAAPYSTQKSSVLPLYENTFQE 960

Query: 961  LQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERFEVDQLQGLRNSVRMELQDLEL 1020
            LQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERFEVDQLQGLRNSVRMELQDLEL
Sbjct: 961  LQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERFEVDQLQGLRNSVRMELQDLEL 1020

Query: 1021 QLEERLLGLEEQLRAVRMPSPFRSSALMGMCGSRSADNLSCPSPLNVMEPVTELMQEQSY 1080
            QLEERLLGLEEQLRAVRMPSPFRSSALMGMCGSRSADNLSCPSPLNVMEPVTELMQEQSY
Sbjct: 1021 QLEERLLGLEEQLRAVRMPSPFRSSALMGMCGSRSADNLSCPSPLNVMEPVTELMQEQSY 1080

Query: 1081 LKSELGLGLGEMGFEIPPGESSESVFSQATSESSSVCSGPSHANRRTGVPSTASVGKSKT 1140
            LKSELGLGLGEMGFEIPPGESSESVFSQATSESSSVCSGPSHANRRTGVPSTASVGKSKT
Sbjct: 1081 LKSELGLGLGEMGFEIPPGESSESVFSQATSESSSVCSGPSHANRRTGVPSTASVGKSKT 1140

Query: 1141 PLVARKKVFRASVALTPTAPSRTGSVQTPPDLESSEEVDAAEGAPEVVGPKSEVEEGHGK 1200
            PLVARKKVFRASVALTPTAPSRTGSVQTPPDLESSEEVDAAEGAPEVVGPKSEVEEGHGK
Sbjct: 1141 PLVARKKVFRASVALTPTAPSRTGSVQTPPDLESSEEVDAAEGAPEVVGPKSEVEEGHGK 1200

Query: 1201 LPSMPAAEEMHKNVEQDELQQVIREI 1226
            LPSMPAAEEMHKNVEQDELQQVIRE+
Sbjct: 1201 LPSMPAAEEMHKNVEQDELQQVIREV 1226


>gi|209862861 hypothetical protein LOC9840 [Homo sapiens]
          Length = 521

 Score =  147 bits (371), Expect = 6e-35
 Identities = 111/328 (33%), Positives = 169/328 (51%), Gaps = 21/328 (6%)

Query: 23  RRKAWAKCRSSWQASETEDLSTEATTQDEEEDEEEDLPGAQLPAAGGRGNVPNEKIAIWL 82
           +R+AW +   +WQ    E+    A  QD  + E   L           GN P  KI  WL
Sbjct: 13  KRRAWLRQSRNWQTQVLEE-EAAAALQDVPDPEPSSLDDVFQ-----EGN-PINKIEDWL 65

Query: 83  KDCRTPLGASLDEQSSSTLKGVLVRNGGSFEDDLSLGAEANHLHESDAQIENCNNILAKE 142
           +DC         E++   +      +G SFEDDL+LGAEA  L  +        + L   
Sbjct: 66  QDCGYS-EEGFSEEAGQFIYNGFCSHGTSFEDDLTLGAEATLLAANGKLFSR--SFLETA 122

Query: 143 RRLQFHQKGRSMNSTG-SGKSSGTVSSVSELLELYEEDPEEILYNLGFGRDEPDIASKIP 201
           R  Q    G S+ S+  +G ++ T SS+SE+L+  +ED E++L++LGFG+++    S+IP
Sbjct: 123 RPCQLLDLGCSLASSSMTGGTNKTSSSISEILDKVQEDAEDVLFSLGFGQEDHKDTSRIP 182

Query: 202 SRFFNSSSFAKGIDIKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVANAFSSLYSQVS 261
           +RFF + S AKGID ++FL +Q++R+E+E+P   L SRF+Q++ L   A+AF  LYS VS
Sbjct: 183 ARFFTTPSQAKGIDFQLFLKSQVRRIEMEDPCLMLASRFKQVQTLAVTADAFFCLYSYVS 242

Query: 262 GTPLQRI-GSMSSVTSNKETDPPP--PLTR----SNTANRLMKTLSKLNLCVDKTEKGES 314
            TP+Q+   S      N  TD P    L+R     +  +RL K +SK+ L    T   + 
Sbjct: 243 KTPVQKFTPSHMFWNCNHPTDVPSIRILSREPEPQSPRDRLRKAISKMCL---YTCPRDR 299

Query: 315 SSPSPSAEKGKILNVSVIEESGNKNDQK 342
             P  +  K   L+  V+E      ++K
Sbjct: 300 PPPPHNTPKRNSLDQVVLEVMDKVKEEK 327


>gi|149363704 hypothetical protein LOC9840 [Homo sapiens]
          Length = 521

 Score =  147 bits (371), Expect = 6e-35
 Identities = 111/328 (33%), Positives = 169/328 (51%), Gaps = 21/328 (6%)

Query: 23  RRKAWAKCRSSWQASETEDLSTEATTQDEEEDEEEDLPGAQLPAAGGRGNVPNEKIAIWL 82
           +R+AW +   +WQ    E+    A  QD  + E   L           GN P  KI  WL
Sbjct: 13  KRRAWLRQSRNWQTQVLEE-EAAAALQDVPDPEPSSLDDVFQ-----EGN-PINKIEDWL 65

Query: 83  KDCRTPLGASLDEQSSSTLKGVLVRNGGSFEDDLSLGAEANHLHESDAQIENCNNILAKE 142
           +DC         E++   +      +G SFEDDL+LGAEA  L  +        + L   
Sbjct: 66  QDCGYS-EEGFSEEAGQFIYNGFCSHGTSFEDDLTLGAEATLLAANGKLFSR--SFLETA 122

Query: 143 RRLQFHQKGRSMNSTG-SGKSSGTVSSVSELLELYEEDPEEILYNLGFGRDEPDIASKIP 201
           R  Q    G S+ S+  +G ++ T SS+SE+L+  +ED E++L++LGFG+++    S+IP
Sbjct: 123 RPCQLLDLGCSLASSSMTGGTNKTSSSISEILDKVQEDAEDVLFSLGFGQEDHKDTSRIP 182

Query: 202 SRFFNSSSFAKGIDIKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVANAFSSLYSQVS 261
           +RFF + S AKGID ++FL +Q++R+E+E+P   L SRF+Q++ L   A+AF  LYS VS
Sbjct: 183 ARFFTTPSQAKGIDFQLFLKSQVRRIEMEDPCLMLASRFKQVQTLAVTADAFFCLYSYVS 242

Query: 262 GTPLQRI-GSMSSVTSNKETDPPP--PLTR----SNTANRLMKTLSKLNLCVDKTEKGES 314
            TP+Q+   S      N  TD P    L+R     +  +RL K +SK+ L    T   + 
Sbjct: 243 KTPVQKFTPSHMFWNCNHPTDVPSIRILSREPEPQSPRDRLRKAISKMCL---YTCPRDR 299

Query: 315 SSPSPSAEKGKILNVSVIEESGNKNDQK 342
             P  +  K   L+  V+E      ++K
Sbjct: 300 PPPPHNTPKRNSLDQVVLEVMDKVKEEK 327


>gi|154937346 coiled-coil domain containing 129 [Homo sapiens]
          Length = 1044

 Score =  124 bits (311), Expect = 6e-28
 Identities = 114/372 (30%), Positives = 166/372 (44%), Gaps = 51/372 (13%)

Query: 150 KGRSMNSTGSGKSSGTVSSVSELLELYEEDPEEILYNLGFGRDEPDIASKIPSRFFNSSS 209
           +G S NS  S  ++    S+ E LE +E DP EIL +LGFG DEPDI  +IP+RF    S
Sbjct: 116 RGTSFNSCYS--TASVPQSIPEWLEFWEIDPVEILLDLGFGADEPDICMQIPARFLGCGS 173

Query: 210 FAKGIDIKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVANAFSSLYSQVSGTPLQRIG 269
            A+GI+I+VFL AQ QRM++ENPN  L  RFRQ+E+L  V NAFSSL S VS  P  R  
Sbjct: 174 AARGINIRVFLEAQKQRMDIENPN--LYGRFRQLEILDHVTNAFSSLLSDVSILP-NRAE 230

Query: 270 SMSSVTSNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAEKGKILNV 329
             +   S + T             +L++  SK N+  D   +                  
Sbjct: 231 EKAGGESVQRTSVSAAKEHRRRMGKLLRRASKQNIRRDCNPE------------------ 272

Query: 330 SVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSDRISDEANSNFNQ 389
             + ES    D+      K  +  + LA        +  +++    S +  D+       
Sbjct: 273 --VSESFKVKDEVFVPFTKPWDCGAELAATSINHKQNHLSLSVEHQSLQACDDLLPYPPH 330

Query: 390 GTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEKEPCA 449
           G  ++Q     S  +K    S +      S+ ++   ++ EN  +               
Sbjct: 331 GLLSKQ-WPCSSMPAKQAPPSCV------SEGSVKGRTQKENLFQTNK------------ 371

Query: 450 PLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTASQHSDSS 509
              + S+ ++  +  DSFEMEEVQS E E  + P     G   ++ D   R  S  SDSS
Sbjct: 372 ---LKSLSHLAGKGPDSFEMEEVQSFEEETGN-PLDMTSGTVGARVD---RANSCQSDSS 424

Query: 510 GFAEDSTDCLSL 521
           GF E+  + L L
Sbjct: 425 GFLEEPLEPLPL 436



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 29/86 (33%), Positives = 49/86 (56%)

Query: 946  QKSSVLPLYENTFQELQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERFEVDQLQ 1005
            Q ++V  L   T  E++ M+     FR  + ++E  ++ QQ +    M+EEER E +QLQ
Sbjct: 852  QDTTVRELCSCTVHEMEAMKTICQSFREYLEEIEQHLMGQQALFSRDMSEEEREEAEQLQ 911

Query: 1006 GLRNSVRMELQDLELQLEERLLGLEE 1031
             LR ++R ++ +LE QL +R   + E
Sbjct: 912  TLREALRQQVAELEFQLGDRAQQIRE 937


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 78/388 (20%), Positives = 145/388 (37%), Gaps = 20/388 (5%)

Query: 307 DKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGS 366
           DK+ +G+  + S  +      N     ES N +  +        ES       K+  +GS
Sbjct: 457 DKSMQGDDPNSSDESNGNDDAN----SESDNNSSSRGDASYNSDES-------KDNGNGS 505

Query: 367 SAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISSH 426
            +   E+ DSD  SD  NS+ N    N      +S   K   +S   +S   S+ + SS 
Sbjct: 506 DSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565

Query: 427 SELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATY 486
           S   +SS+  S   S+      +  +  S  +       S   +   S++       +  
Sbjct: 566 SSDSDSSDSNS---SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622

Query: 487 QLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTV 546
           +   +KS+ D      S  SDS   + DS    S ++    +S  +  SS  S  S+++ 
Sbjct: 623 KSDSSKSESD------SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676

Query: 547 TSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENTG 606
           +S   D +  +       + +  ES          ++  +D   S S D    N+ +++ 
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736

Query: 607 TKQSTCSPGDHIIEITEVEEDLFPAETVELLREASAESDVGKSSESEFTQYTTHHILKSL 666
           +  S+ S        +    D   +       ++S  SD   SS S  +  +++    S 
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD 796

Query: 667 ASIEAKCSDMSSENTTGPPSSMDRVNTA 694
           +S  +  S+ S  + +   S  D  N++
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSS 824



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 81/423 (19%), Positives = 151/423 (35%), Gaps = 58/423 (13%)

Query: 309 TEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSA 368
           ++  +S+S S S       + S   +S + ++            SS  +   +  S SS 
Sbjct: 569 SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628

Query: 369 AVTENADSDRISDEANSNFNQGTENEQSKE------------------------------ 398
           + ++++DSD  SD ++SN +  ++N  S +                              
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688

Query: 399 -TQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIR 457
            + S +S    ES       DSD + SS S   NSS+  S + S  +    +  +  S  
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS--DSSDSSNSSDSSDS 746

Query: 458 NIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTASQHSDSSGFAE---- 513
           +  +   DS +  +  ++   +    ++     + S   +    +S  SDSS  ++    
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806

Query: 514 -------DSTDCLSLNHLQVQESLQAMGSSADSCDSETTVTSLGEDLATPTAQDQPYFNE 566
                  DS+D  S N      S  +  SS  S  S+++ +S G D  +    D    ++
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866

Query: 567 SEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENTGTKQSTCSPGDHIIEITEVEE 626
           S + S                   S S D    N   N+     + +  D     +    
Sbjct: 867 SSDSS--------------DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912

Query: 627 DLFPAETVELLREASAESDVGKSSESEFTQYTTHHILKSLASIEAKCSDMSSENTTGPPS 686
           D   +       E+S  SD   SS+S  +  ++     S +S  +  SD S+ + +   +
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972

Query: 687 SMD 689
           S D
Sbjct: 973 SSD 975



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 118/662 (17%), Positives = 232/662 (35%), Gaps = 41/662 (6%)

Query: 32   SSWQASETEDL---STEATTQDEEEDEEEDLPGAQLPAAGGRGNVPNEKIAIWLKDCRTP 88
            +S+ + E++D    S     +D++ D   D   +     G  GN  N+K      D    
Sbjct: 491  ASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDK-----SDSGKG 545

Query: 89   LGASLDEQSSSTLKGVLVRNGGSFEDDLSLGAEANHLHESDAQIENCNNILAKERRLQFH 148
               S D  SS +       +  S +   S  +++N   +SD+   + ++    +     +
Sbjct: 546  KSDSSDSDSSDSSN-----SSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSN 600

Query: 149  QKGRSMNSTGSGKSSGTVSSVSELLELYEEDPEEILYNLGFGRDEPDIASKIPSRFFNSS 208
                S +S  S  S  + SS S+      E             D  D  SK  S   NSS
Sbjct: 601  SSDSSDSSDSSDSSDSSDSSDSKSDSSKSES------------DSSDSDSKSDSSDSNSS 648

Query: 209  SFAKGIDIKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVANAFSSLYSQVSGTPLQRI 268
              +   D     ++       ++ + + +S        +  +++  S  S  S       
Sbjct: 649  DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708

Query: 269  GSMSSVTSNKETDPPPPLTRSNTANRLMKTLSKLNL----CVDKTEKGESSSPSPSAEKG 324
             S SS +S+           SN+++    + S  +       + ++  +SS  S S++  
Sbjct: 709  DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768

Query: 325  KILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSDRISDEAN 384
               + S   +S N +D            SS  +        S ++ + ++DS   SD +N
Sbjct: 769  DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828

Query: 385  SNFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPE 444
            S+ +  + N  S  + S +S  G +S    ++ DS  +  S    ++S+   S   S   
Sbjct: 829  SSDSSDSSN-SSDSSDSSDSSDGSDSD-SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN 886

Query: 445  KEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTASQ 504
            +   +  +  S  +  +   DS    +   +   +    ++     + S        +S 
Sbjct: 887  ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946

Query: 505  HSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTVTSLGEDLATPTAQDQPYF 564
             SDSS  ++ S    S N     +S     +S+DS DS  +  S     ++ ++      
Sbjct: 947  SSDSSNSSDSSNSSDSSNSSDSSDS-----NSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001

Query: 565  NESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENTGTKQSTCSPGDHIIEITEV 624
            N S+             + +      S S D    +   ++     +    D     +  
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD-----SSN 1056

Query: 625  EEDLFPAETVELLREASAESDVGKSSESEFTQYTTHHILKSLASIEAKCSDMSSENTTGP 684
              D   +       ++S  SD   SSES  +  +++    S +S  +  SD S  + +  
Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116

Query: 685  PS 686
             S
Sbjct: 1117 SS 1118



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 55/283 (19%), Positives = 108/283 (38%), Gaps = 3/283 (1%)

Query: 270  SMSSVTSNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAEKGKILNV 329
            S  S  SN+ ++       SN+++      S  +   D +   +SS  S S++     + 
Sbjct: 879  SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938

Query: 330  SVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSDRISDEANSNFNQ 389
            S   +S + +D  +         SS  +   +  S  S+  + ++DS   SD ++S+ + 
Sbjct: 939  SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998

Query: 390  GTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEKEPCA 449
             + N       S  S   + S   +S   SD + SS S   + S   S    + +    +
Sbjct: 999  DSSNSSDSSDSSDSS---DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1055

Query: 450  PLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTASQHSDSS 509
              +  S  +  +   DS +  +   +   +    ++     + S        +S  SDSS
Sbjct: 1056 NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1115

Query: 510  GFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTVTSLGED 552
              ++ S    S +     +S  +  SS  S  SE++ +S   D
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD 1158



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 71/384 (18%), Positives = 141/384 (36%), Gaps = 5/384 (1%)

Query: 192  DEPDIASKIPSRFFNSSSFAKGIDIKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVAN 251
            D  D ++   S   +SS+ +   D      +       +N N + +S        +  +N
Sbjct: 893  DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952

Query: 252  AFSSLYSQVSGTPLQRIGSMSSVTSNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEK 311
            +  S  S  S        S SS +S+         +  ++ +      S  +   D ++ 
Sbjct: 953  SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012

Query: 312  GESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGS----S 367
             +SS+ S S+      N S   +S + +D            SS  +   +    S    S
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072

Query: 368  AAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHS 427
            +  ++++DS   SD ++S+ +  + +       S  S   + S   +S   SD + SS S
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132

Query: 428  ELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATYQ 487
               + S   S    + E    +  +  S  +  +   DS +  +  ++   +    ++  
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192

Query: 488  LGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTVT 547
               + S        +S  SDSS  ++ S    S +     ES  +  SS DS DS  +  
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS-DSSDSSNSSD 1251

Query: 548  SLGEDLATPTAQDQPYFNESEEES 571
            S     ++ +  D    ++S+ +S
Sbjct: 1252 SSDSSDSSDSTSDSNDESDSQSKS 1275



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 56/311 (18%), Positives = 111/311 (35%), Gaps = 6/311 (1%)

Query: 307  DKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGS 366
            D +   +SS+ S S++     N S   +S N +D            SS  +   +    S
Sbjct: 955  DSSNSSDSSNSSDSSDS----NSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1010

Query: 367  SAAVTENA-DSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISS 425
             ++ + N+ DS   SD +NS+ +  + +       S  S   + S   +S   SD + SS
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070

Query: 426  HSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPAT 485
             S   + S   S    + +    +  +  S  +  +   DS +  +   +   +    ++
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130

Query: 486  YQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETT 545
                 + S        +S+ SDSS  ++ S    S +     +S  +  SS DS DS  +
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS-DSSDSSDS 1189

Query: 546  VTSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENT 605
              S     ++ ++      + S+           + + +      S S D    +   N+
Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNS 1249

Query: 606  GTKQSTCSPGD 616
                 +    D
Sbjct: 1250 SDSSDSSDSSD 1260



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 50/255 (19%), Positives = 95/255 (37%), Gaps = 16/255 (6%)

Query: 307  DKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQK-SQKIMKKKESSSMLATVKEEVSG 365
            D ++  +SS  S S++       S   +S N +D   S       +SS    +     S 
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121

Query: 366  SSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISS 425
            +S+  ++++DS   SD +NS+ +  +         S  S   + S   +S   SD + SS
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181

Query: 426  HSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPAT 485
             S   + S   S    + +    +  +  S  +  +   DS +  +   +   +    ++
Sbjct: 1182 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241

Query: 486  YQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETT 545
                 + S        +S  SDSS    DS D         +   Q+   + ++  S++ 
Sbjct: 1242 DSSDSSNSS------DSSDSSDSSDSTSDSND---------ESDSQSKSGNGNNNGSDSD 1286

Query: 546  VTSLGEDLATPTAQD 560
              S G D    T+ D
Sbjct: 1287 SDSEGSDSNHSTSDD 1301


>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
           polyclonal antibodies [Homo sapiens]
          Length = 1430

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 86/388 (22%), Positives = 156/388 (40%), Gaps = 57/388 (14%)

Query: 268 IGSMSSVTSNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAEKG--- 324
           +GSM S+TS++E+   PPL+ + T      +        D    G+ SS    AEK    
Sbjct: 219 LGSMDSLTSSEESSERPPLS-TLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSD 277

Query: 325 ---KILNVSV-IEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSDRIS 380
               + N++  I+E        SQK   +K +S      K+ VS  +  + E   S  +S
Sbjct: 278 DKDSVSNIATEIKEGPISGTVSSQKQPAEKATSD----EKDSVSNIATEIKEGQQSGTVS 333

Query: 381 DEANSNFNQGTENEQSKETQSHESKLGEESGIVES-----------KLDSDFNISSHSEL 429
            +  S +    + + S    +     G +SG V S           K DS  NI+  +E+
Sbjct: 334 PQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIA--TEI 391

Query: 430 ENSSELKSVHISTPEKEPCAPLTI---PSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATY 486
           ++  +  +V   + +K+P    T     S+ NI T+ KD  +   V S +  A       
Sbjct: 392 KDGLQCGTV---SSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPA------- 441

Query: 487 QLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTV 546
            L  T  + D +L  A++  D      + ++ +S    Q Q +L+A     DS     T 
Sbjct: 442 -LKATTDEEDSVLNIATEIKDG-----EKSETVS---SQKQPALKATTDEEDSVSIIATE 492

Query: 547 TSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENTG 606
              GE   T +++ +P    + +E         +  + +  ++K G  +  +  + +   
Sbjct: 493 IKDGEKSGTVSSRKKPALKATSDEK--------DSFSNITREKKDG--EISRTVSSQKPP 542

Query: 607 TKQSTCSPGDHIIEITEVEEDLFPAETV 634
             ++T    D ++ I   E+D   + TV
Sbjct: 543 ALKATSDEEDSVLSIAREEKDGEKSRTV 570



 Score = 34.7 bits (78), Expect = 0.59
 Identities = 65/308 (21%), Positives = 119/308 (38%), Gaps = 44/308 (14%)

Query: 310 EKGESSS----PSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSG 365
           EK E+ S    P+  A   +  +VS+I       ++      +KK +    +  K+  S 
Sbjct: 463 EKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSN 522

Query: 366 SSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVES---------- 415
            +    +   S  +S +        ++ E S  + + E K GE+S  V S          
Sbjct: 523 ITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATR 582

Query: 416 -KLDSDFNISSHSELENSSELKSVHISTPEKEPCAPLTIP---SIRNIMTQQKDSFEMEE 471
            + DS  NI+   +    +   S H     K+P    T     S+ N+ T+ KD    E+
Sbjct: 583 DEKDSLLNIARGKKYGEKTRRVSSH-----KQPALKATSDKENSVPNMATETKD----EQ 633

Query: 472 VQSTEGEAPHVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQ 531
           +  T       PA   L  T  K+D +    ++  D       S+        Q Q + +
Sbjct: 634 ISGTVSSQKQ-PA---LKATSDKKDSVSNIPTEIKDGQQSGTVSS--------QKQLAWK 681

Query: 532 AMGSSADSCDSETTVTSLGEDLATPTAQDQPYFNES--EEESLVPLQKGL---EKAAAVA 586
           A     DS  +  T    G+   T ++Q QP    +  E++S+  + + +   EK+  V+
Sbjct: 682 ATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVS 741

Query: 587 DKRKSGSQ 594
            +++S  +
Sbjct: 742 PQKQSAQK 749


>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 948

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 80/337 (23%), Positives = 136/337 (40%), Gaps = 54/337 (16%)

Query: 268 IGSMSSVTSNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAEKGKIL 327
           +G M S+TS++E+   PPL+          TL + +    K       SP P    GK+ 
Sbjct: 219 LGGMDSLTSSEESSERPPLS--------TLTLKEADPS-SKAAMRRKDSPPP----GKVS 265

Query: 328 NVSVIEESGNKNDQKSQKIMKKKESSSMLAT-VKE-EVSGSSAAVTENADSDRISDEANS 385
           +     E    +D         K+S S +AT +KE  +SG+ ++  + A+    SDE +S
Sbjct: 266 SQKQPAEKATSDD---------KDSVSNIATEIKEGPISGTVSSQKQPAEK-ATSDEKDS 315

Query: 386 NFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEK 445
             N  TE ++ +++ +   +      ++  K  S  NI++       S   S      +K
Sbjct: 316 VSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVS-----SQK 370

Query: 446 EPCAPLT---IPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTA 502
           +P +  T     S  NI T+ KD  +   V S +  A        L  T  + D +   A
Sbjct: 371 QPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPA--------LKATTDEEDSVSNIA 422

Query: 503 SQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTVTSLGEDLATPTAQDQP 562
           ++  D       S+        Q Q +L+A     DS  +  T    GE   T ++Q  P
Sbjct: 423 TEIKDGEKSGTVSS--------QKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPP 474

Query: 563 YFNESEEE-----SLVPLQKGLEKAAAVADKRKSGSQ 594
               + +E     S+    K  EK+  V+ ++K  S+
Sbjct: 475 ALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASK 511



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 68/310 (21%), Positives = 122/310 (39%), Gaps = 47/310 (15%)

Query: 307 DKTEKGESSSPSPSA------EKGKILNVSVIEESGNKNDQKSQKIM-KKKESSSMLATV 359
           D  + G  SS  P A      E+G +L+++      NK+ +KS+ +  +KK +S   +  
Sbjct: 461 DGEKSGTVSSQKPPALTATSDEEGSVLSIA----RENKDGEKSRTVSSRKKPASKATSDE 516

Query: 360 KEEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDS 419
           K+  S  +    +   S ++S +        ++ E S    + E+K GE+S  V S+   
Sbjct: 517 KDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 576

Query: 420 DFNISSHSELENSSEL----------KSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEM 469
               SS    E  S L          K+  +S+ +K        PS+    + +KDSF  
Sbjct: 577 GLKASSD---EKDSVLNIARGKKYGEKTKRVSSRKK--------PSL-EATSDEKDSFSN 624

Query: 470 EEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQE- 528
              +  +GE           ++  K   L  T+ +     G A ++ D      +  ++ 
Sbjct: 625 ITREKKDGEISR-------KVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKP 677

Query: 529 -SLQAMGSSADSCDSETTVTSLGEDLATPTAQDQPYFNESEEE-----SLVPLQKGLEKA 582
             L+A     DS  +       GE   T ++Q  P    + +E     S+    K  EK+
Sbjct: 678 PGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKS 737

Query: 583 AAVADKRKSG 592
             V+ ++ SG
Sbjct: 738 RTVSSEKPSG 747



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 44/207 (21%), Positives = 87/207 (42%), Gaps = 28/207 (13%)

Query: 275 TSNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPS----PSAEKGKILNVS 330
           T    +  PP L  ++     + ++++ N   +K+    S  PS     SAEK  +LN++
Sbjct: 703 TRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIA 762

Query: 331 VIEESGNKNDQKSQKIMKKK---------ESSSMLATVKEEVSGSSAAVTENADS---DR 378
                G K  +K++++  +K         E  S+L   +E+  G  +    +        
Sbjct: 763 ----RGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKA 818

Query: 379 ISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSV 438
           I D+ +S  N  TE +  + + +  S+          K DS  NI   +E+++  +  +V
Sbjct: 819 ICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIP--TEIKDGQQSGTV 876

Query: 439 HISTPEKEPCAPLTIP---SIRNIMTQ 462
              +P+K+    +      S+ NI T+
Sbjct: 877 ---SPQKQSAQKVIFKKKVSLLNIATR 900



 Score = 34.7 bits (78), Expect = 0.59
 Identities = 74/415 (17%), Positives = 159/415 (38%), Gaps = 57/415 (13%)

Query: 269 GSMSSVTSNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAEKGKILN 328
           G   +V+S K+        ++++A  +   +     C   + + + +  + + E+  + N
Sbjct: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420

Query: 329 VSVI----EESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSD----RIS 380
           ++      E+SG  + QK   +    +    ++ +  E+     + T ++         S
Sbjct: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480

Query: 381 DEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNIS-SHSELENSSELKSVH 439
           DE  S  +   EN+  +++++  S+    S     + DS  NI+    + E S ++ S  
Sbjct: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSS-- 538

Query: 440 ISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLL 499
               +K P    T     +++   +++ + E+ ++   E P       L  +  ++D +L
Sbjct: 539 ----QKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP-----GLKASSDEKDSVL 589

Query: 500 RTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTVTSLGEDLATPTAQ 559
             A        + E +    S    + + SL+A     DS  + T     GE     ++Q
Sbjct: 590 NIAR----GKKYGEKTKRVSS----RKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQ 641

Query: 560 DQPYF--NESEEESLVPL---QKGLEKAAAVADKR-----------------KSGSQDFP 597
             P       EE+S++ +    K  EK+  V+ ++                   G +D  
Sbjct: 642 KPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGE 701

Query: 598 QCNTI--ENTGTKQSTCSPGDHIIEITEVEEDLFPAETVEL-----LREASAESD 645
           +  T+  +   T ++T    D ++ I    +D   + TV       L+  SAE D
Sbjct: 702 KTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKD 756


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 68/262 (25%), Positives = 107/262 (40%), Gaps = 35/262 (13%)

Query: 284 PPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKS 343
           P   RS   N  M +       +   E GE+S  + + + G      ++E    K  +KS
Sbjct: 220 PESIRSERGNSRMNSAG-----MKSKESGENSEQANTQDSG---GSQLLEHPSRKIFRKS 271

Query: 344 QKIMKKKESSSMLATVKEEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHE 403
           +   +   S        EEV   S   TEN++S           ++G   E SKE  S E
Sbjct: 272 RISEEDDRSELDDNNTMEEVKSDS---TENSNSRDTGLSQPRRDSKGDSQEDSKENLSQE 328

Query: 404 SKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQ 463
                +    ES  ++  N+SS    ENSSE +   +S    +   P T     + +  Q
Sbjct: 329 ESQNVDGPSSESSQEA--NLSSQ---ENSSESQEEVVSESRGDNPDPTT-----SYVEDQ 378

Query: 464 KDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTA-SQHSDSSGFAEDSTDCLSLN 522
           +DS       S+E ++ H        L+ SK +     A S+ S+S  F+E+S +     
Sbjct: 379 EDS------DSSEEDSSHT-------LSHSKSESREEQADSESSESLNFSEESPESPEDE 425

Query: 523 HLQVQESLQAMGSSADSCDSET 544
           +   QE LQ+  SSA+S   E+
Sbjct: 426 NSSSQEGLQSHSSSAESQSEES 447



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 64/288 (22%), Positives = 111/288 (38%), Gaps = 38/288 (13%)

Query: 330 SVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADS----DRISDEANS 385
           S+  E GN     +   MK KES         + SG S  +   +       RIS+E + 
Sbjct: 222 SIRSERGNSRMNSAG--MKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDR 279

Query: 386 NFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEK 445
           +        +  ++ S E+    ++G+ + + DS  +    S+ EN S+ +S ++  P  
Sbjct: 280 SELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSK-ENLSQEESQNVDGPSS 338

Query: 446 EPCAPLTIPSIRNIMTQQKDSFEMEEVQS-TEGEAPHVPATYQLGLTKSKRDHLLRTASQ 504
           E           N+ +Q+  S   EEV S + G+ P    +Y                  
Sbjct: 339 ESSQEA------NLSSQENSSESQEEVVSESRGDNPDPTTSY---------------VED 377

Query: 505 HSDSSGFAEDSTDCLSLNHLQVQE---------SLQAMGSSADSCDSETTVTSLGEDLAT 555
             DS    EDS+  LS +  + +E         SL     S +S + E + +  G    +
Sbjct: 378 QEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHS 437

Query: 556 PTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIE 603
            +A+ Q   + SEE+          K  + + + KS S++  Q   IE
Sbjct: 438 SSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIE 485



 Score = 34.7 bits (78), Expect = 0.59
 Identities = 45/169 (26%), Positives = 74/169 (43%), Gaps = 27/169 (15%)

Query: 300 SKLNLCVDKTEK--GESSSPSPSAEKGKILNVS-----VIEESGNKNDQKSQKIMKKKE- 351
           SK NL  ++++   G SS  S  A      N S     V+ ES   N   +   ++ +E 
Sbjct: 321 SKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQED 380

Query: 352 -------SSSMLATVKEEV------SGSSAAVTENADSDRISDEANSNFNQGTENEQSK- 397
                  SS  L+  K E       S SS ++  + +S    ++ NS+  +G ++  S  
Sbjct: 381 SDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSA 440

Query: 398 ETQSHESKLGEESGIVE----SKLDSDFNISSHSELENSSELKSVHIST 442
           E+QS ES   E+    +    SK DS+ +  S S  E   +LK++ I +
Sbjct: 441 ESQSEESHSEEDDSDSQDSSRSKEDSN-STESKSSSEEDGQLKNIEIES 488


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 68/262 (25%), Positives = 107/262 (40%), Gaps = 35/262 (13%)

Query: 284 PPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKS 343
           P   RS   N  M +       +   E GE+S  + + + G      ++E    K  +KS
Sbjct: 204 PESIRSERGNSRMNSAG-----MKSKESGENSEQANTQDSG---GSQLLEHPSRKIFRKS 255

Query: 344 QKIMKKKESSSMLATVKEEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHE 403
           +   +   S        EEV   S   TEN++S           ++G   E SKE  S E
Sbjct: 256 RISEEDDRSELDDNNTMEEVKSDS---TENSNSRDTGLSQPRRDSKGDSQEDSKENLSQE 312

Query: 404 SKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQ 463
                +    ES  ++  N+SS    ENSSE +   +S    +   P T     + +  Q
Sbjct: 313 ESQNVDGPSSESSQEA--NLSSQ---ENSSESQEEVVSESRGDNPDPTT-----SYVEDQ 362

Query: 464 KDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTA-SQHSDSSGFAEDSTDCLSLN 522
           +DS       S+E ++ H        L+ SK +     A S+ S+S  F+E+S +     
Sbjct: 363 EDS------DSSEEDSSHT-------LSHSKSESREEQADSESSESLNFSEESPESPEDE 409

Query: 523 HLQVQESLQAMGSSADSCDSET 544
           +   QE LQ+  SSA+S   E+
Sbjct: 410 NSSSQEGLQSHSSSAESQSEES 431



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 64/288 (22%), Positives = 111/288 (38%), Gaps = 38/288 (13%)

Query: 330 SVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADS----DRISDEANS 385
           S+  E GN     +   MK KES         + SG S  +   +       RIS+E + 
Sbjct: 206 SIRSERGNSRMNSAG--MKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDR 263

Query: 386 NFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEK 445
           +        +  ++ S E+    ++G+ + + DS  +    S+ EN S+ +S ++  P  
Sbjct: 264 SELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSK-ENLSQEESQNVDGPSS 322

Query: 446 EPCAPLTIPSIRNIMTQQKDSFEMEEVQS-TEGEAPHVPATYQLGLTKSKRDHLLRTASQ 504
           E           N+ +Q+  S   EEV S + G+ P    +Y                  
Sbjct: 323 ESSQEA------NLSSQENSSESQEEVVSESRGDNPDPTTSY---------------VED 361

Query: 505 HSDSSGFAEDSTDCLSLNHLQVQE---------SLQAMGSSADSCDSETTVTSLGEDLAT 555
             DS    EDS+  LS +  + +E         SL     S +S + E + +  G    +
Sbjct: 362 QEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHS 421

Query: 556 PTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIE 603
            +A+ Q   + SEE+          K  + + + KS S++  Q   IE
Sbjct: 422 SSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIE 469



 Score = 34.7 bits (78), Expect = 0.59
 Identities = 45/169 (26%), Positives = 74/169 (43%), Gaps = 27/169 (15%)

Query: 300 SKLNLCVDKTEK--GESSSPSPSAEKGKILNVS-----VIEESGNKNDQKSQKIMKKKE- 351
           SK NL  ++++   G SS  S  A      N S     V+ ES   N   +   ++ +E 
Sbjct: 305 SKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQED 364

Query: 352 -------SSSMLATVKEEV------SGSSAAVTENADSDRISDEANSNFNQGTENEQSK- 397
                  SS  L+  K E       S SS ++  + +S    ++ NS+  +G ++  S  
Sbjct: 365 SDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSA 424

Query: 398 ETQSHESKLGEESGIVE----SKLDSDFNISSHSELENSSELKSVHIST 442
           E+QS ES   E+    +    SK DS+ +  S S  E   +LK++ I +
Sbjct: 425 ESQSEESHSEEDDSDSQDSSRSKEDSN-STESKSSSEEDGQLKNIEIES 472


>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 1524

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 79/333 (23%), Positives = 134/333 (40%), Gaps = 54/333 (16%)

Query: 268 IGSMSSVTSNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAEKGKIL 327
           +G M S+TS++E+   PPL+          TL + +    K       SP P    GK+ 
Sbjct: 219 LGGMDSLTSSEESSERPPLS--------TLTLKEADPS-SKAAMRRKDSPPP----GKVS 265

Query: 328 NVSVIEESGNKNDQKSQKIMKKKESSSMLAT-VKE-EVSGSSAAVTENADSDRISDEANS 385
           +     E    +D         K+S S +AT +KE  +SG+ ++  + A+    SDE +S
Sbjct: 266 SQKQPAEKATSDD---------KDSVSNIATEIKEGPISGTVSSQKQPAEK-ATSDEKDS 315

Query: 386 NFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEK 445
             N  TE ++ +++ +   +      ++  K  S  NI++       S   S      +K
Sbjct: 316 VSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVS-----SQK 370

Query: 446 EPCAPLT---IPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTA 502
           +P +  T     S  NI T+ KD  +   V S +  A        L  T  + D +   A
Sbjct: 371 QPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPA--------LKATTDEEDSVSNIA 422

Query: 503 SQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTVTSLGEDLATPTAQDQP 562
           ++  D       S+        Q Q +L+A     DS  +  T    GE   T ++Q  P
Sbjct: 423 TEIKDGEKSGTVSS--------QKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPP 474

Query: 563 YFNESEEE-----SLVPLQKGLEKAAAVADKRK 590
               + +E     S+    K  EK+  V+ ++K
Sbjct: 475 ALTATSDEEGSVLSIARENKDGEKSRTVSSRKK 507



 Score = 37.4 bits (85), Expect = 0.091
 Identities = 64/317 (20%), Positives = 124/317 (39%), Gaps = 28/317 (8%)

Query: 307 DKTEKGESSSPSPSA------EKGKILNVSVIEESGNKNDQKSQKIM-KKKESSSMLATV 359
           D  + G  SS  P A      E+G +L+++      NK+ +KS+ +  +KK +    +  
Sbjct: 461 DGEKSGTVSSQKPPALTATSDEEGSVLSIA----RENKDGEKSRTVSSRKKPALKATSDE 516

Query: 360 KEEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDS 419
           K+  S  +    +   S ++S +        ++ E S    + E+K GE+S  V S+   
Sbjct: 517 KDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 576

Query: 420 DFNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEA 479
               SS +E ++   +        + +  +    PS+    + +KDSF     +  +GE 
Sbjct: 577 GLKASS-AEKDSVLNIARGKKDGEKTKRVSSRKKPSL-EATSDEKDSFSNITREKKDGEI 634

Query: 480 PHVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQE--SLQAMGSSA 537
                     ++  K   L  T+ +     G A ++ D      +  ++   L+A     
Sbjct: 635 SR-------KVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEK 687

Query: 538 DSCDSETTVTSLGEDLATPTAQDQPYFNE-SEEESLVPLQKGLEKAAAVADKRKSGSQDF 596
           DS  +       GE   T ++  QP      ++E  VP       A    D++ SG+   
Sbjct: 688 DSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVP-----NMATEKKDEQISGTVSC 742

Query: 597 PQCNTIENTGTKQSTCS 613
            +   ++ T  K+ + S
Sbjct: 743 QKQPALKATSDKKDSVS 759


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 109/561 (19%), Positives = 198/561 (35%), Gaps = 46/561 (8%)

Query: 237  TSRFRQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSNKETDPP---PPLTRSNTAN 293
            +S    +     V +   + Y+QVS +P    GS    ++ +E  PP    P++ +  A+
Sbjct: 1881 SSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVAS 1940

Query: 294  RLMKTLSK--LNLCVDKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKE 351
              + TLS    +     T   ++SS   +A+   +   +  E S           +    
Sbjct: 1941 SEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSS 2000

Query: 352  SSSMLATVKEEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKL---GE 408
             +S L+T   + S  +   TE + S   +   +   +  +E           + L    E
Sbjct: 2001 EASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSE 2060

Query: 409  ESGIVESKLDSDFNISSHSELENS--SELKSVHISTP-EKEP--------CAPLTIPSIR 457
             + +  + +DS   +++ +E  +S  +E  S+ IS P E  P          P+  P   
Sbjct: 2061 GNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEAS 2120

Query: 458  NIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTD 517
             + T   DS     + STE  +  +P       T +  D      S    ++  A  +  
Sbjct: 2121 TLSTTPVDS-NSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAIS 2179

Query: 518  CLSLNHLQVQESLQAMGSSADSCDSETTVTSLGEDLATPTAQDQPYFNESEEESLVPLQK 577
             LS   +   ++   + +S ++  S TT        +TP+    P+ +       V   +
Sbjct: 2180 TLSTTPV---DTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSE 2236

Query: 578  GLEKAAAVADKR---KSGSQDFPQCNTIENTGTKQSTCSPGDHIIEITEVEEDLFPAETV 634
                +A   D      + ++      T E T    ST S G   +    V   L     V
Sbjct: 2237 ASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEV 2296

Query: 635  ELLREASAESDVGKSSESEFTQYTTHHILKSLASIEAKCSDMSSENTTGPPSSMDRVNTA 694
              L     +S+         T +TT        S EA     ++E T+ P S+    NT 
Sbjct: 2297 STLSTTPVDSN---------TPFTT--------STEASSPPPTAEGTSMPTSTSSEGNTP 2339

Query: 695  LQRAQMKVCSLSNQRMGRSLLKSKDLLKQRYLFAKAGYPLRRSQ--SLPTTLLSPVRV-V 751
            L R  +    +++           D       +++AG     +   S+PT+  S     +
Sbjct: 2340 LTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPL 2399

Query: 752  SSVNVRLSPGKETRCSPPSFT 772
            +SV V   P   +  S  S T
Sbjct: 2400 TSVPVSTMPVVSSEASTHSTT 2420



 Score = 37.7 bits (86), Expect = 0.070
 Identities = 116/567 (20%), Positives = 200/567 (35%), Gaps = 61/567 (10%)

Query: 143 RRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDPEEILYNLGFGRDEPDIAS-KIP 201
           ++L  H +  S  +T +G +S  V      L     +PE          D P ++S ++ 
Sbjct: 53  QQLSQHVRTGSAANTATGTTSTNVVEPRMYLSC-STNPEMTSIESSVTSDTPGVSSTRMT 111

Query: 202 SRFFNSSSFAKGIDIKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVANAFSSLYSQVS 261
                ++S +      +F S+       E+ +   T     + + T    + SS  + VS
Sbjct: 112 PTESRTTSESTSDSTTLFPSS------TEDTSSPTTPEGTDVPMSTPSEESISSTMAFVS 165

Query: 262 GTPLQRIGSMSSVTSNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSA 321
             PL    + +S+T   + D   PLT S  A                       S SP+ 
Sbjct: 166 TAPLPSFEAYTSLTY--KVDMSTPLTTSTQA-----------------------SSSPTT 200

Query: 322 EKGKILNVSVIEESGNKNDQKSQKIMKKKESSSM-LATVKEEVSGSSAAVTENADSDRIS 380
            +   +  S   E            MK   S ++ L T   E+S +   ++  A S   +
Sbjct: 201 PESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEIS-TPVTISAQASSSPTT 259

Query: 381 DEANSNFNQGTENEQSKETQSHESKL----GEESGIVESKLDSDFNISSHSELENS---S 433
            E  S  N       +  T+   S +     E S +  +   ++  + + +E  +S   +
Sbjct: 260 AEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTA 319

Query: 434 ELKSVHISTPEKEPCAPLTIP--SIRNIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLT 491
           E  S+  ST   E   PLT    S   + T +  +  +  V            T  L  T
Sbjct: 320 EGTSIPTST-YTEGSTPLTSTPASTMPVATSEMSTLSITPVD-----------TSTLVTT 367

Query: 492 KSKRDHLLRTASQHSD-SSGFAEDSTDCLSLNHLQVQ-ESLQAMGSSADSCDSETTVTSL 549
            ++   L  TA   S  +S  +E ST   ++    +   S +A  +S    DS+T VT+ 
Sbjct: 368 STEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTA 427

Query: 550 GEDLATP-TAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENTGTK 608
            E  ++P TA+D      +  E   PL         VA    S     P  +  + T + 
Sbjct: 428 SEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTST 487

Query: 609 QSTCSPGDHIIEITEVEEDLFPAETVELLREASAESDVGKSSESEFTQYTTHHILKSLAS 668
           +++ SP     E+  +        +  L   + +   V  S  S  +            S
Sbjct: 488 EASSSP--PTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTS 545

Query: 669 IEAKCSDMSSENTTGPPSSMDRVNTAL 695
            EA  S  + E T+ P S+    +T L
Sbjct: 546 SEASSSSTTPEGTSIPTSTPSEGSTPL 572



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 74/323 (22%), Positives = 126/323 (39%), Gaps = 35/323 (10%)

Query: 309  TEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSA 368
            T   E+SS SP+  +G  + +S   E   +    S  +     +SS  +T+    + +S 
Sbjct: 2960 TTSAEASS-SPTTAEGTSMPISTPGE--RRTPLTSMSVSTMPVASSEASTLSRTPADTST 3016

Query: 369  AVTENADSDRISDEAN------SNFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFN 422
             VT + ++      A       S  ++G+    S    +    + E S +  + +DS+  
Sbjct: 3017 PVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSP 3076

Query: 423  ISSHSELENS---SELKSVHISTPEKEPCAPLT-IPSIRNIMTQQKDSFEMEEVQSTEGE 478
            + + +E+ +S   +E  S+ IST   E   PLT +P    + T    S  +  + +T   
Sbjct: 3077 VVTSTEVSSSPTPAEGTSMPIST-YSEGSTPLTGVP----VSTTPVTSSAISTLSTT--- 3128

Query: 479  APHVPATYQLGLTKSKRDHLLRTASQHSD--SSGFAEDSTDCLSLNHLQVQESLQAMGS- 535
                P      +T S   H   T S+ +   +S  +E ST    L ++ V   L      
Sbjct: 3129 ----PVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTP---LTYMPVSTMLVVSSED 3181

Query: 536  ---SADSCDSETTVTSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSG 592
               SA   D+ T VT+  E  ++ TA+       +  E + PL         VA    S 
Sbjct: 3182 STLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASI 3241

Query: 593  SQDFP-QCNTIENTGTKQSTCSP 614
                P   NT   T T+ S+  P
Sbjct: 3242 LSTTPVDSNTPLTTSTEASSSPP 3264



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 14/123 (11%)

Query: 1097 PPGESSESVFSQATSESSSVCSGPSHANRRTGVPSTASVGKSKTPLVARKKVFRASVALT 1156
            P   S+E+  S  TSE +S+     ++N   G     S+  S TP+V+ +    ++++ T
Sbjct: 1367 PVTTSTEACSSPTTSEGTSM----PNSNPSEGTTPLTSIPVSTTPVVSSEA---STLSAT 1419

Query: 1157 PTAPSRTGSVQTPPDLESSEEVDAAEGAPEVVGPKSEVEEGHGKLPSMPAAEEMHKNVEQ 1216
            P   S  G+       E++     AEG   +  P S   EG   L S+P +     N E 
Sbjct: 1420 PVDTSTPGTTSA----EATSSPTTAEG---ISIPTSTPSEGKTPLKSIPVSNTPVANSEA 1472

Query: 1217 DEL 1219
              L
Sbjct: 1473 STL 1475



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 30/111 (27%), Positives = 49/111 (44%), Gaps = 14/111 (12%)

Query: 1097 PPGESSESVFSQATSESSSVCSGPSHANRRTGVPSTASVGKSKTPLVARKKVFRASVALT 1156
            P   S+E+  S  T+E +S+ + P       G    AS+  S TP+V+ +     +++ T
Sbjct: 2427 PVTTSTEASSSPTTAEGTSIPTSPPSE----GTTPLASMPVSTTPVVSSEA---GTLSTT 2479

Query: 1157 PTAPSRTGSVQTPPDLESSEEVDAAEGAPEVVGPKSEVEEGHGKLPSMPAA 1207
            P   S        P   S+E   +   A ++V P S   EG   L S+P +
Sbjct: 2480 PVDTST-------PMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVS 2523



 Score = 31.2 bits (69), Expect = 6.5
 Identities = 40/167 (23%), Positives = 58/167 (34%), Gaps = 26/167 (15%)

Query: 1063 SPLNVMEPVTELMQEQSYLKSELGLGLGEMGFEIPPGESSESVFSQATSESSSVCSGPSH 1122
            +P++   PVT   +  S   +  G  +       PP E +  + S   S +  V S    
Sbjct: 2420 TPVDTSTPVTTSTEASSSPTTAEGTSIPTS----PPSEGTTPLASMPVSTTPVVSSEAGT 2475

Query: 1123 ANRR---TGVPSTASVGKSKTPLVARKKVFRAS-------------VALTPTAPSRTGSV 1166
             +     T  P T S   S +P  A   V   S             V+ TP A     ++
Sbjct: 2476 LSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTL 2535

Query: 1167 QTPPD------LESSEEVDAAEGAPEVVGPKSEVEEGHGKLPSMPAA 1207
             T P       + S+E   +A  A     P S   EG   L SMP +
Sbjct: 2536 STTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVS 2582


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 52/205 (25%), Positives = 83/205 (40%), Gaps = 31/205 (15%)

Query: 275 TSNKETDPPPPLTRSNTANRLMKTLSKLNLCVDK----TEKGESSSPSPSAEKGKILNVS 330
           TS K   PPPP      +++   T         K    + KG  S+P  S       + S
Sbjct: 266 TSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFS 325

Query: 331 VIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGS------------SAAVTENADSDR 378
             + + +K+  + +K+  + E       ++ E S S            S+    ++ SD 
Sbjct: 326 DKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDS 385

Query: 379 ISD---EANSNFNQG-----TENEQSKETQSHESKLGEE-SGIVESKLDSDFNISSHSEL 429
            SD   E + N +QG      E+ QS+E+   +S  GEE +G      DS  + S  SE 
Sbjct: 386 SSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSD-SES 444

Query: 430 ENSSELKSVHISTPEKEPCAPLTIP 454
           +NS++      S P +EP  P   P
Sbjct: 445 DNSAD-----SSLPSREPPPPQKPP 464


>gi|28373194 adhesion regulating molecule 1 precursor [Homo sapiens]
          Length = 407

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 47/172 (27%), Positives = 78/172 (45%), Gaps = 21/172 (12%)

Query: 1086 GLGLGEM-GFEIPPGESSESVFSQATSESSSVC-SGPSHANRRTGVPSTASVGKSKTPLV 1143
            G GL  + G   PPG SS S    + S+S++V  S  + + R T  PS  +   + +P  
Sbjct: 188  GPGLASLLGSSGPPGSSSSS---SSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSP 244

Query: 1144 ARKKVFRASVALTPTAPSRTGSVQT-------PPDLESSEEVDAAEG-APEVVGP---KS 1192
            A      AS A +PT P +   +Q+       P      ++VD A    PE++ P    +
Sbjct: 245  APSSGNGASTAASPTQPIQLSDLQSILATMNVPAGPAGGQQVDLASVLTPEIMAPILANA 304

Query: 1193 EVEEGHGKLPSMPAAEEMHKNVEQDELQQVIREIK-ESIVGEIRREIVSGLL 1243
            +V+E    LP +P+ E + +    DE+Q  +   + +  +G     + SG L
Sbjct: 305  DVQE--RLLPYLPSGESLPQTA--DEIQNTLTSPQFQQALGMFSAALASGQL 352


>gi|28373192 adhesion regulating molecule 1 precursor [Homo sapiens]
          Length = 407

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 47/172 (27%), Positives = 78/172 (45%), Gaps = 21/172 (12%)

Query: 1086 GLGLGEM-GFEIPPGESSESVFSQATSESSSVC-SGPSHANRRTGVPSTASVGKSKTPLV 1143
            G GL  + G   PPG SS S    + S+S++V  S  + + R T  PS  +   + +P  
Sbjct: 188  GPGLASLLGSSGPPGSSSSS---SSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSP 244

Query: 1144 ARKKVFRASVALTPTAPSRTGSVQT-------PPDLESSEEVDAAEG-APEVVGP---KS 1192
            A      AS A +PT P +   +Q+       P      ++VD A    PE++ P    +
Sbjct: 245  APSSGNGASTAASPTQPIQLSDLQSILATMNVPAGPAGGQQVDLASVLTPEIMAPILANA 304

Query: 1193 EVEEGHGKLPSMPAAEEMHKNVEQDELQQVIREIK-ESIVGEIRREIVSGLL 1243
            +V+E    LP +P+ E + +    DE+Q  +   + +  +G     + SG L
Sbjct: 305  DVQE--RLLPYLPSGESLPQTA--DEIQNTLTSPQFQQALGMFSAALASGQL 352


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 8/118 (6%)

Query: 1148 VFRASVALTPTAPSRTGSVQTPPDLESSEEVDAAEGAPEVVGPKSE-----VEEGHG-KL 1201
            V   +++LTP+APS T    + P+ +  E  D+AEG    V P+ E     V E +G +L
Sbjct: 2595 VSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLEL 2654

Query: 1202 PSMPAAEE-MHKNVEQDELQQVIREIKESIVG-EIRREIVSGLLAAVSSSKASNSKQD 1257
            P   A++E + + +E D   + + E K      E  +E+V+  +AA S+S ++ S  +
Sbjct: 2655 PPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPE 2712


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 60/248 (24%), Positives = 102/248 (41%), Gaps = 45/248 (18%)

Query: 208 SSFAKGIDIKVFLSAQMQRMEVENPNYALTSRFR-----QIEVLTTVANAFSSLYSQVSG 262
           S +AK    K+FL+        + P   L S F+     Q+  L+   N  ++ Y ++S 
Sbjct: 591 SKYAK----KIFLA--------QKPAPLLESPFKDRDHFQLGTLSHTLNIKATGYLELSN 638

Query: 263 ----TPLQRIGSMSSVTSNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPS 318
                P   + ++  +   KE  P     + N+A +      +     D +   ES S S
Sbjct: 639 WPEVAPDPSVRNVEVIELAKEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGS 698

Query: 319 PSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSDR 378
            S E+G         ESG + D         ++SS   ++ ++  SG  + +     + R
Sbjct: 699 ESGEQG---------ESGEEGD-------SNEDSSEDSSSEQDSESGRESGLENKRTAKR 742

Query: 379 ISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSV 438
            S     + ++  E E  K +++ +S   E S I +S  DS+    S SE E+ SE + V
Sbjct: 743 NSKAKGKSDSEDGEKENEK-SKTSDSSNDESSSIEDSSSDSE----SESEPESESESRRV 797

Query: 439 HISTPEKE 446
              T EKE
Sbjct: 798 ---TKEKE 802



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 51/204 (25%), Positives = 82/204 (40%), Gaps = 13/204 (6%)

Query: 283 PPPLTRSNTANRLMKTLSKLN--LCVDKTEKGESSSPSPSAEKGKILNVSVIEESGNKND 340
           P PL  S   +R    L  L+  L +  T   E S+    A    + NV VIE +  K  
Sbjct: 603 PAPLLESPFKDRDHFQLGTLSHTLNIKATGYLELSNWPEVAPDPSVRNVEVIELA--KEW 660

Query: 341 QKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQ 400
             + K  ++  +    +  +EE   S ++    ++S   S E   +  +G  NE S E  
Sbjct: 661 TPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDS 720

Query: 401 SHE--SKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRN 458
           S E  S+ G ESG+ E+K  +  N  +  + ++    K       EK   +  +     +
Sbjct: 721 SSEQDSESGRESGL-ENKRTAKRNSKAKGKSDSEDGEKE-----NEKSKTSDSSNDESSS 774

Query: 459 IMTQQKDSFEMEEVQSTEGEAPHV 482
           I     DS E E    +E E+  V
Sbjct: 775 IEDSSSDS-ESESEPESESESRRV 797


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 53/222 (23%), Positives = 90/222 (40%), Gaps = 39/222 (17%)

Query: 267 RIGSMSSVTSNKET----------DPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSS 316
           ++GS+S + + K T          + P P  R+       K       C ++ ++ E   
Sbjct: 623 QLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTK-------CSNREKRKEKEK 675

Query: 317 PSPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADS 376
           P  S  +G         ESG      S     + ES S   +  E  SG S++ ++N D 
Sbjct: 676 PFYSDSEG---------ESGPTESADSDP---ESESESDSKSSSESGSGESSSESDNEDQ 723

Query: 377 DRISDEANSNFNQGTENEQSKE--TQSHESKLGEESGIVESKLDSDFNISSHSELENSSE 434
           D   ++      +G+E+EQS+E   +  + K+ E  G   S  +   + SS SE E +SE
Sbjct: 724 DEDEEKG-----RGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSE 778

Query: 435 LKSVHI---STPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQ 473
            +   +   S   K P +  + P+ + I     + F    VQ
Sbjct: 779 SEEEQLEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPSVQ 820


>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
           12A isoform b [Homo sapiens]
          Length = 943

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 119/541 (21%), Positives = 200/541 (36%), Gaps = 79/541 (14%)

Query: 331 VIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSDRISDEANSNFNQG 390
           +IE + N ++ +SQK  K KE+      ++ E    +A+  E+ + +++ +E      +G
Sbjct: 214 LIESTANMDNNQSQKTFKNKET----LIIEPE---KNASRIESLEQEKVDEE-----EEG 261

Query: 391 TENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSS-ELKSVHISTPEKEPCA 449
            ++E S  ++  E    E+    E++ D    ++S +    SS +   V ++TP      
Sbjct: 262 KKDESSCSSEEDE----EDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQ 317

Query: 450 PLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTASQHSDSS 509
                 I+   T        EE +  E      PAT++LGL K+     L  A   +   
Sbjct: 318 ATPTSPIKKFPTTATKISPKEEERKDES-----PATWRLGLRKTGSYGAL--AEITASKE 370

Query: 510 GFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTVTSLGEDLATPTAQDQPYFNESEE 569
           G  E  T  ++ +      S   + SS D+ + E            PT   +       E
Sbjct: 371 GQKEKDTAGVTRS-----ASSPRLSSSLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIE 425

Query: 570 ESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENTGTKQSTCSPG---DHIIEITEVEE 626
           E        L  +++    R+    D  + +++    T   +CS G   D +I  +    
Sbjct: 426 EKENRDSSSLRTSSSYT--RRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPST 483

Query: 627 DLFPAET------VELLREASAESDVGKSSESEFTQYTTHHILKSLASIEAKCSDMSSEN 680
              P  T        LL   S  + +   S S  TQ +T + L +  S E        E 
Sbjct: 484 TSTPTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTE-------KEK 536

Query: 681 TTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDLLKQRYLFAKAGYPLRRSQSL 740
            + P +    V   +  A     +L+    G   + S   +++R          RRS   
Sbjct: 537 DSVPTAVTIPVAPTVVNAAASTTTLTTTTAG--TVSSTTEVRER----------RRS--- 581

Query: 741 PTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEEQELEK--------RVMEHDG 792
               L+PVR   S + R +  ++ R S  S T   T  + QE EK        R  E + 
Sbjct: 582 ---YLTPVRDEESESQRKARSRQARQSRRS-TQGVTLTDLQEAEKTIGRSRSTRTREQEN 637

Query: 793 QSLVKSTIFISPSSVKKEEAPQSEAPRVEEC--HHGRT--PTCSRLAPPPMSQSTCSLHS 848
           +   K          K+EE  +SE  R +E    + RT   T  R  P   S ST    S
Sbjct: 638 EEKEKEE-KEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSS 696

Query: 849 I 849
           +
Sbjct: 697 L 697



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 103/542 (19%), Positives = 195/542 (35%), Gaps = 61/542 (11%)

Query: 276 SNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAE-KGKILNVSVIEE 334
           S  ETD   PL     AN      + + +       G+++  SP  +       +S  EE
Sbjct: 280 SEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQATPTSPIKKFPTTATKISPKEE 339

Query: 335 SGNKNDQKSQKI-MKKKESSSMLATVKEEVSG----SSAAVTENADSDRISDEANSNFNQ 389
                   + ++ ++K  S   LA +     G     +A VT +A S R+S   ++    
Sbjct: 340 ERKDESPATWRLGLRKTGSYGALAEITASKEGQKEKDTAGVTRSASSPRLSSSLDN---- 395

Query: 390 GTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEKEPCA 449
                + KE  S  ++L   +  +  +L S  +I    E  +SS L++    T  K    
Sbjct: 396 -----KEKEKDSKGTRLAYVAPTIPRRLASTSDI-EEKENRDSSSLRTSSSYTRRKWEDD 449

Query: 450 PLTIPSIRNIMTQQKD-SFEMEEVQSTEGEAPHVPATYQL----GLTKSKRDHLLRTASQ 504
                S+    T  K  SF   +        P   +T  +    GL KS    L  T++ 
Sbjct: 450 LKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTSTPTVTSAAGLQKSL---LSSTSTT 506

Query: 505 HSDSSGFAEDSTDCLSLNHLQVQESLQAMGSS-------------ADSCDSETTVTSLGE 551
              ++G +   T   + N L  ++S +    S              ++  S TT+T+   
Sbjct: 507 TKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTTTLTTTTA 566

Query: 552 DLATPTAQ----DQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENTGT 607
              + T +     + Y     +E     +K   + A  + +   G          +  G 
Sbjct: 567 GTVSSTTEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGR 626

Query: 608 KQSTCSPGDHIIEITEVEEDLFPAETVELLREASAESDVGKSSESEFTQYTTHHILKSLA 667
            +ST +      E  + E++    E  E  +E+        S E E+ Q  +    ++  
Sbjct: 627 SRSTRTREQENEEKEKEEKEKQDKEKQEEKKESET------SREDEYKQKYS----RTYD 676

Query: 668 SIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDLLKQRYLF 727
               +   +S+ ++T P SS+  ++++L  +     +  N  +G +   S+ + K+    
Sbjct: 677 ETYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQ--LNRPNSLVGITSAYSRGITKENERE 734

Query: 728 AKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEEQELEKRV 787
            +     R  +        P     S+  R  P ++ R +  SF  + + E EQE +   
Sbjct: 735 GEK----REEEKEGEDKSQP----KSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDT 786

Query: 788 ME 789
            E
Sbjct: 787 EE 788


>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
           12A isoform a [Homo sapiens]
          Length = 1030

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 119/541 (21%), Positives = 200/541 (36%), Gaps = 79/541 (14%)

Query: 331 VIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSDRISDEANSNFNQG 390
           +IE + N ++ +SQK  K KE+      ++ E    +A+  E+ + +++ +E      +G
Sbjct: 301 LIESTANMDNNQSQKTFKNKET----LIIEPE---KNASRIESLEQEKVDEE-----EEG 348

Query: 391 TENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSS-ELKSVHISTPEKEPCA 449
            ++E S  ++  E    E+    E++ D    ++S +    SS +   V ++TP      
Sbjct: 349 KKDESSCSSEEDE----EDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQ 404

Query: 450 PLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTASQHSDSS 509
                 I+   T        EE +  E      PAT++LGL K+     L  A   +   
Sbjct: 405 ATPTSPIKKFPTTATKISPKEEERKDES-----PATWRLGLRKTGSYGAL--AEITASKE 457

Query: 510 GFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTVTSLGEDLATPTAQDQPYFNESEE 569
           G  E  T  ++ +      S   + SS D+ + E            PT   +       E
Sbjct: 458 GQKEKDTAGVTRS-----ASSPRLSSSLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIE 512

Query: 570 ESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENTGTKQSTCSPG---DHIIEITEVEE 626
           E        L  +++    R+    D  + +++    T   +CS G   D +I  +    
Sbjct: 513 EKENRDSSSLRTSSSYT--RRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPST 570

Query: 627 DLFPAET------VELLREASAESDVGKSSESEFTQYTTHHILKSLASIEAKCSDMSSEN 680
              P  T        LL   S  + +   S S  TQ +T + L +  S E        E 
Sbjct: 571 TSTPTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTE-------KEK 623

Query: 681 TTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDLLKQRYLFAKAGYPLRRSQSL 740
            + P +    V   +  A     +L+    G   + S   +++R          RRS   
Sbjct: 624 DSVPTAVTIPVAPTVVNAAASTTTLTTTTAG--TVSSTTEVRER----------RRS--- 668

Query: 741 PTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEEQELEK--------RVMEHDG 792
               L+PVR   S + R +  ++ R S  S T   T  + QE EK        R  E + 
Sbjct: 669 ---YLTPVRDEESESQRKARSRQARQSRRS-TQGVTLTDLQEAEKTIGRSRSTRTREQEN 724

Query: 793 QSLVKSTIFISPSSVKKEEAPQSEAPRVEEC--HHGRT--PTCSRLAPPPMSQSTCSLHS 848
           +   K          K+EE  +SE  R +E    + RT   T  R  P   S ST    S
Sbjct: 725 EEKEKEE-KEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSS 783

Query: 849 I 849
           +
Sbjct: 784 L 784



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 103/542 (19%), Positives = 195/542 (35%), Gaps = 61/542 (11%)

Query: 276 SNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAE-KGKILNVSVIEE 334
           S  ETD   PL     AN      + + +       G+++  SP  +       +S  EE
Sbjct: 367 SEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQATPTSPIKKFPTTATKISPKEE 426

Query: 335 SGNKNDQKSQKI-MKKKESSSMLATVKEEVSG----SSAAVTENADSDRISDEANSNFNQ 389
                   + ++ ++K  S   LA +     G     +A VT +A S R+S   ++    
Sbjct: 427 ERKDESPATWRLGLRKTGSYGALAEITASKEGQKEKDTAGVTRSASSPRLSSSLDN---- 482

Query: 390 GTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEKEPCA 449
                + KE  S  ++L   +  +  +L S  +I    E  +SS L++    T  K    
Sbjct: 483 -----KEKEKDSKGTRLAYVAPTIPRRLASTSDI-EEKENRDSSSLRTSSSYTRRKWEDD 536

Query: 450 PLTIPSIRNIMTQQKD-SFEMEEVQSTEGEAPHVPATYQL----GLTKSKRDHLLRTASQ 504
                S+    T  K  SF   +        P   +T  +    GL KS    L  T++ 
Sbjct: 537 LKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTSTPTVTSAAGLQKSL---LSSTSTT 593

Query: 505 HSDSSGFAEDSTDCLSLNHLQVQESLQAMGSS-------------ADSCDSETTVTSLGE 551
              ++G +   T   + N L  ++S +    S              ++  S TT+T+   
Sbjct: 594 TKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTTTLTTTTA 653

Query: 552 DLATPTAQ----DQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENTGT 607
              + T +     + Y     +E     +K   + A  + +   G          +  G 
Sbjct: 654 GTVSSTTEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGR 713

Query: 608 KQSTCSPGDHIIEITEVEEDLFPAETVELLREASAESDVGKSSESEFTQYTTHHILKSLA 667
            +ST +      E  + E++    E  E  +E+        S E E+ Q  +    ++  
Sbjct: 714 SRSTRTREQENEEKEKEEKEKQDKEKQEEKKESET------SREDEYKQKYS----RTYD 763

Query: 668 SIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDLLKQRYLF 727
               +   +S+ ++T P SS+  ++++L  +     +  N  +G +   S+ + K+    
Sbjct: 764 ETYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQ--LNRPNSLVGITSAYSRGITKENERE 821

Query: 728 AKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEEQELEKRV 787
            +     R  +        P     S+  R  P ++ R +  SF  + + E EQE +   
Sbjct: 822 GEK----REEEKEGEDKSQP----KSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDT 873

Query: 788 ME 789
            E
Sbjct: 874 EE 875


>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
           12A isoform a [Homo sapiens]
          Length = 1030

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 119/541 (21%), Positives = 200/541 (36%), Gaps = 79/541 (14%)

Query: 331 VIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSDRISDEANSNFNQG 390
           +IE + N ++ +SQK  K KE+      ++ E    +A+  E+ + +++ +E      +G
Sbjct: 301 LIESTANMDNNQSQKTFKNKET----LIIEPE---KNASRIESLEQEKVDEE-----EEG 348

Query: 391 TENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSS-ELKSVHISTPEKEPCA 449
            ++E S  ++  E    E+    E++ D    ++S +    SS +   V ++TP      
Sbjct: 349 KKDESSCSSEEDE----EDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQ 404

Query: 450 PLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTASQHSDSS 509
                 I+   T        EE +  E      PAT++LGL K+     L  A   +   
Sbjct: 405 ATPTSPIKKFPTTATKISPKEEERKDES-----PATWRLGLRKTGSYGAL--AEITASKE 457

Query: 510 GFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTVTSLGEDLATPTAQDQPYFNESEE 569
           G  E  T  ++ +      S   + SS D+ + E            PT   +       E
Sbjct: 458 GQKEKDTAGVTRS-----ASSPRLSSSLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIE 512

Query: 570 ESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENTGTKQSTCSPG---DHIIEITEVEE 626
           E        L  +++    R+    D  + +++    T   +CS G   D +I  +    
Sbjct: 513 EKENRDSSSLRTSSSYT--RRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPST 570

Query: 627 DLFPAET------VELLREASAESDVGKSSESEFTQYTTHHILKSLASIEAKCSDMSSEN 680
              P  T        LL   S  + +   S S  TQ +T + L +  S E        E 
Sbjct: 571 TSTPTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTE-------KEK 623

Query: 681 TTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDLLKQRYLFAKAGYPLRRSQSL 740
            + P +    V   +  A     +L+    G   + S   +++R          RRS   
Sbjct: 624 DSVPTAVTIPVAPTVVNAAASTTTLTTTTAG--TVSSTTEVRER----------RRS--- 668

Query: 741 PTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEEQELEK--------RVMEHDG 792
               L+PVR   S + R +  ++ R S  S T   T  + QE EK        R  E + 
Sbjct: 669 ---YLTPVRDEESESQRKARSRQARQSRRS-TQGVTLTDLQEAEKTIGRSRSTRTREQEN 724

Query: 793 QSLVKSTIFISPSSVKKEEAPQSEAPRVEEC--HHGRT--PTCSRLAPPPMSQSTCSLHS 848
           +   K          K+EE  +SE  R +E    + RT   T  R  P   S ST    S
Sbjct: 725 EEKEKEE-KEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSS 783

Query: 849 I 849
           +
Sbjct: 784 L 784



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 103/542 (19%), Positives = 195/542 (35%), Gaps = 61/542 (11%)

Query: 276 SNKETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAE-KGKILNVSVIEE 334
           S  ETD   PL     AN      + + +       G+++  SP  +       +S  EE
Sbjct: 367 SEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQATPTSPIKKFPTTATKISPKEE 426

Query: 335 SGNKNDQKSQKI-MKKKESSSMLATVKEEVSG----SSAAVTENADSDRISDEANSNFNQ 389
                   + ++ ++K  S   LA +     G     +A VT +A S R+S   ++    
Sbjct: 427 ERKDESPATWRLGLRKTGSYGALAEITASKEGQKEKDTAGVTRSASSPRLSSSLDN---- 482

Query: 390 GTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEKEPCA 449
                + KE  S  ++L   +  +  +L S  +I    E  +SS L++    T  K    
Sbjct: 483 -----KEKEKDSKGTRLAYVAPTIPRRLASTSDI-EEKENRDSSSLRTSSSYTRRKWEDD 536

Query: 450 PLTIPSIRNIMTQQKD-SFEMEEVQSTEGEAPHVPATYQL----GLTKSKRDHLLRTASQ 504
                S+    T  K  SF   +        P   +T  +    GL KS    L  T++ 
Sbjct: 537 LKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTSTPTVTSAAGLQKSL---LSSTSTT 593

Query: 505 HSDSSGFAEDSTDCLSLNHLQVQESLQAMGSS-------------ADSCDSETTVTSLGE 551
              ++G +   T   + N L  ++S +    S              ++  S TT+T+   
Sbjct: 594 TKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTTTLTTTTA 653

Query: 552 DLATPTAQ----DQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFPQCNTIENTGT 607
              + T +     + Y     +E     +K   + A  + +   G          +  G 
Sbjct: 654 GTVSSTTEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGR 713

Query: 608 KQSTCSPGDHIIEITEVEEDLFPAETVELLREASAESDVGKSSESEFTQYTTHHILKSLA 667
            +ST +      E  + E++    E  E  +E+        S E E+ Q  +    ++  
Sbjct: 714 SRSTRTREQENEEKEKEEKEKQDKEKQEEKKESET------SREDEYKQKYS----RTYD 763

Query: 668 SIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKSKDLLKQRYLF 727
               +   +S+ ++T P SS+  ++++L  +     +  N  +G +   S+ + K+    
Sbjct: 764 ETYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQ--LNRPNSLVGITSAYSRGITKENERE 821

Query: 728 AKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEEQELEKRV 787
            +     R  +        P     S+  R  P ++ R +  SF  + + E EQE +   
Sbjct: 822 GEK----REEEKEGEDKSQP----KSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDT 873

Query: 788 ME 789
            E
Sbjct: 874 EE 875


>gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]
          Length = 1265

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 59/276 (21%), Positives = 113/276 (40%), Gaps = 69/276 (25%)

Query: 245  VLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSNKETDPPPPLTRSNTANRLMKTLSKLNL 304
            +LT   N  +S  ++ S T +     +  +TS  ++DP  P+    T  +   TL+K +L
Sbjct: 997  ILTKAKNKLASQLTESSQTSISLESDLKHITSEADSDPGNPVELCKTQKQSTTTLNKKDL 1056

Query: 305  -CVDKTEKGE----------------SSSPSPSAEKGKIL---------NVSVIEESGNK 338
              V++ ++GE                 +S  PS E  +++           +V E++  +
Sbjct: 1057 PFVEEIKEGECQVKKVNKMTSKSKKRKTSIDPSPESHEVMERILDSVQGKSTVSEQADKE 1116

Query: 339  NDQKSQKIMKKKE------------------SSSMLATVKEEV------SGSSAAVTEN- 373
            N+ +++K++K K                     S   +V+E +      SG +  + EN 
Sbjct: 1117 NNLENEKMVKNKPDFYTKAFRSLSEIHSPNIQDSSFDSVREGLVPLSVSSGKNVIIKENF 1176

Query: 374  ----ADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLDSDFNISSHSEL 429
                + + ++SD+         E+E+  + +   ++  ++SGI +  L    N S  S  
Sbjct: 1177 ALECSPAFQVSDD---------EHEKMNKMKFKVNRRTQKSGIGDRPLQDLSNTSFVSNN 1227

Query: 430  ENSSELKSVHIS---TPEKEPCAPLTI--PSIRNIM 460
               SE KS  +S   T  +  C P     PS+R+ M
Sbjct: 1228 TAESENKSEDLSSERTSRRRRCTPFYFKEPSLRDKM 1263


>gi|109637767 calpastatin isoform j [Homo sapiens]
          Length = 667

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 104/487 (21%), Positives = 188/487 (38%), Gaps = 47/487 (9%)

Query: 260 VSGTPLQRIGSMSSVTSNK--ETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSP 317
           +SG P  +     S+T     E+ P  P  +S     L   +  L    ++TE+  ++  
Sbjct: 79  ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG-GPEETEEENTTYT 137

Query: 318 SPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSD 377
            P  E    ++ + IEE G +      K  +       L   KE ++G  A  ++    D
Sbjct: 138 GP--EVSDPMSSTYIEELGKREVTIPPKYRE-------LLAKKEGITGPPADSSKPIGPD 188

Query: 378 RISDEANSNFNQGTENEQSKETQSHESK---LGEESGIVESKL---DSDFNISSHSELEN 431
              D  +S+F  G+     K+T+  ES      + +G V S     +    +   +  + 
Sbjct: 189 DAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQ 248

Query: 432 SSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPH----VPATYQ 487
           + E  S  + T + EP   L + SI+ +   +    ++E+    +   P      PAT +
Sbjct: 249 ALEALSASLGTRQAEP--ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDK 306

Query: 488 LG---LTKSKRDHLLRTASQHSDSSGFAEDSTDCL---SLNHLQVQESLQAMGSSADSCD 541
            G   L + +     R+ S+  D      D ++C    S    + +ES  A  +      
Sbjct: 307 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAV 366

Query: 542 SETTVTSLGEDLATPTAQDQPYFNESEE---ESLVPLQKGLEKAAAVADKRKSGSQDFPQ 598
             T++ S+      P        +++ E   +SL   +   E    V DK K  +++  +
Sbjct: 367 CRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 426

Query: 599 CNTIENTGTKQSTCSPGDHIIEITEVE-EDLFPAETVELLREASAESDVGKSSESEFTQY 657
               E  G K+ T  P   + E+ + + + L P E+ E L   S +  +   SE     +
Sbjct: 427 ----EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE----DF 478

Query: 658 TTHHILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKS 717
           +      SL   +AK +   SE  +  P+S     T    A  +  S S++ +  +L K 
Sbjct: 479 SGPQNASSLKFEDAKLAAAISEVVSQTPAS-----TTQAGAPPRDTSQSDKDLDDALDKL 533

Query: 718 KDLLKQR 724
            D L QR
Sbjct: 534 SDSLGQR 540


>gi|109637765 calpastatin isoform i [Homo sapiens]
          Length = 708

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 104/487 (21%), Positives = 188/487 (38%), Gaps = 47/487 (9%)

Query: 260 VSGTPLQRIGSMSSVTSNK--ETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSP 317
           +SG P  +     S+T     E+ P  P  +S     L   +  L    ++TE+  ++  
Sbjct: 120 ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG-GPEETEEENTTYT 178

Query: 318 SPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSD 377
            P  E    ++ + IEE G +      K  +       L   KE ++G  A  ++    D
Sbjct: 179 GP--EVSDPMSSTYIEELGKREVTIPPKYRE-------LLAKKEGITGPPADSSKPIGPD 229

Query: 378 RISDEANSNFNQGTENEQSKETQSHESK---LGEESGIVESKL---DSDFNISSHSELEN 431
              D  +S+F  G+     K+T+  ES      + +G V S     +    +   +  + 
Sbjct: 230 DAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQ 289

Query: 432 SSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPH----VPATYQ 487
           + E  S  + T + EP   L + SI+ +   +    ++E+    +   P      PAT +
Sbjct: 290 ALEALSASLGTRQAEP--ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDK 347

Query: 488 LG---LTKSKRDHLLRTASQHSDSSGFAEDSTDCL---SLNHLQVQESLQAMGSSADSCD 541
            G   L + +     R+ S+  D      D ++C    S    + +ES  A  +      
Sbjct: 348 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAV 407

Query: 542 SETTVTSLGEDLATPTAQDQPYFNESEE---ESLVPLQKGLEKAAAVADKRKSGSQDFPQ 598
             T++ S+      P        +++ E   +SL   +   E    V DK K  +++  +
Sbjct: 408 CRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 467

Query: 599 CNTIENTGTKQSTCSPGDHIIEITEVE-EDLFPAETVELLREASAESDVGKSSESEFTQY 657
               E  G K+ T  P   + E+ + + + L P E+ E L   S +  +   SE     +
Sbjct: 468 ----EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE----DF 519

Query: 658 TTHHILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKS 717
           +      SL   +AK +   SE  +  P+S     T    A  +  S S++ +  +L K 
Sbjct: 520 SGPQNASSLKFEDAKLAAAISEVVSQTPAS-----TTQAGAPPRDTSQSDKDLDDALDKL 574

Query: 718 KDLLKQR 724
            D L QR
Sbjct: 575 SDSLGQR 581


>gi|109637763 calpastatin isoform h [Homo sapiens]
          Length = 769

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 104/487 (21%), Positives = 188/487 (38%), Gaps = 47/487 (9%)

Query: 260 VSGTPLQRIGSMSSVTSNK--ETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSP 317
           +SG P  +     S+T     E+ P  P  +S     L   +  L    ++TE+  ++  
Sbjct: 181 ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG-GPEETEEENTTYT 239

Query: 318 SPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSD 377
            P  E    ++ + IEE G +      K  +       L   KE ++G  A  ++    D
Sbjct: 240 GP--EVSDPMSSTYIEELGKREVTIPPKYRE-------LLAKKEGITGPPADSSKPIGPD 290

Query: 378 RISDEANSNFNQGTENEQSKETQSHESK---LGEESGIVESKL---DSDFNISSHSELEN 431
              D  +S+F  G+     K+T+  ES      + +G V S     +    +   +  + 
Sbjct: 291 DAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQ 350

Query: 432 SSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPH----VPATYQ 487
           + E  S  + T + EP   L + SI+ +   +    ++E+    +   P      PAT +
Sbjct: 351 ALEALSASLGTRQAEP--ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDK 408

Query: 488 LG---LTKSKRDHLLRTASQHSDSSGFAEDSTDCL---SLNHLQVQESLQAMGSSADSCD 541
            G   L + +     R+ S+  D      D ++C    S    + +ES  A  +      
Sbjct: 409 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAV 468

Query: 542 SETTVTSLGEDLATPTAQDQPYFNESEE---ESLVPLQKGLEKAAAVADKRKSGSQDFPQ 598
             T++ S+      P        +++ E   +SL   +   E    V DK K  +++  +
Sbjct: 469 CRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 528

Query: 599 CNTIENTGTKQSTCSPGDHIIEITEVE-EDLFPAETVELLREASAESDVGKSSESEFTQY 657
               E  G K+ T  P   + E+ + + + L P E+ E L   S +  +   SE     +
Sbjct: 529 ----EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE----DF 580

Query: 658 TTHHILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKS 717
           +      SL   +AK +   SE  +  P+S     T    A  +  S S++ +  +L K 
Sbjct: 581 SGPQNASSLKFEDAKLAAAISEVVSQTPAS-----TTQAGAPPRDTSQSDKDLDDALDKL 635

Query: 718 KDLLKQR 724
            D L QR
Sbjct: 636 SDSLGQR 642


>gi|109637761 calpastatin isoform g [Homo sapiens]
          Length = 772

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 104/487 (21%), Positives = 188/487 (38%), Gaps = 47/487 (9%)

Query: 260 VSGTPLQRIGSMSSVTSNK--ETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSP 317
           +SG P  +     S+T     E+ P  P  +S     L   +  L    ++TE+  ++  
Sbjct: 184 ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG-GPEETEEENTTYT 242

Query: 318 SPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSD 377
            P  E    ++ + IEE G +      K  +       L   KE ++G  A  ++    D
Sbjct: 243 GP--EVSDPMSSTYIEELGKREVTIPPKYRE-------LLAKKEGITGPPADSSKPIGPD 293

Query: 378 RISDEANSNFNQGTENEQSKETQSHESK---LGEESGIVESKL---DSDFNISSHSELEN 431
              D  +S+F  G+     K+T+  ES      + +G V S     +    +   +  + 
Sbjct: 294 DAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQ 353

Query: 432 SSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPH----VPATYQ 487
           + E  S  + T + EP   L + SI+ +   +    ++E+    +   P      PAT +
Sbjct: 354 ALEALSASLGTRQAEP--ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDK 411

Query: 488 LG---LTKSKRDHLLRTASQHSDSSGFAEDSTDCL---SLNHLQVQESLQAMGSSADSCD 541
            G   L + +     R+ S+  D      D ++C    S    + +ES  A  +      
Sbjct: 412 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAV 471

Query: 542 SETTVTSLGEDLATPTAQDQPYFNESEE---ESLVPLQKGLEKAAAVADKRKSGSQDFPQ 598
             T++ S+      P        +++ E   +SL   +   E    V DK K  +++  +
Sbjct: 472 CRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 531

Query: 599 CNTIENTGTKQSTCSPGDHIIEITEVE-EDLFPAETVELLREASAESDVGKSSESEFTQY 657
               E  G K+ T  P   + E+ + + + L P E+ E L   S +  +   SE     +
Sbjct: 532 ----EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE----DF 583

Query: 658 TTHHILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKS 717
           +      SL   +AK +   SE  +  P+S     T    A  +  S S++ +  +L K 
Sbjct: 584 SGPQNASSLKFEDAKLAAAISEVVSQTPAS-----TTQAGAPPRDTSQSDKDLDDALDKL 638

Query: 718 KDLLKQR 724
            D L QR
Sbjct: 639 SDSLGQR 645


>gi|109637759 calpastatin isoform f [Homo sapiens]
          Length = 750

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 104/487 (21%), Positives = 188/487 (38%), Gaps = 47/487 (9%)

Query: 260 VSGTPLQRIGSMSSVTSNK--ETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSP 317
           +SG P  +     S+T     E+ P  P  +S     L   +  L    ++TE+  ++  
Sbjct: 162 ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG-GPEETEEENTTYT 220

Query: 318 SPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSD 377
            P  E    ++ + IEE G +      K  +       L   KE ++G  A  ++    D
Sbjct: 221 GP--EVSDPMSSTYIEELGKREVTIPPKYRE-------LLAKKEGITGPPADSSKPIGPD 271

Query: 378 RISDEANSNFNQGTENEQSKETQSHESK---LGEESGIVESKL---DSDFNISSHSELEN 431
              D  +S+F  G+     K+T+  ES      + +G V S     +    +   +  + 
Sbjct: 272 DAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQ 331

Query: 432 SSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPH----VPATYQ 487
           + E  S  + T + EP   L + SI+ +   +    ++E+    +   P      PAT +
Sbjct: 332 ALEALSASLGTRQAEP--ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDK 389

Query: 488 LG---LTKSKRDHLLRTASQHSDSSGFAEDSTDCL---SLNHLQVQESLQAMGSSADSCD 541
            G   L + +     R+ S+  D      D ++C    S    + +ES  A  +      
Sbjct: 390 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAV 449

Query: 542 SETTVTSLGEDLATPTAQDQPYFNESEE---ESLVPLQKGLEKAAAVADKRKSGSQDFPQ 598
             T++ S+      P        +++ E   +SL   +   E    V DK K  +++  +
Sbjct: 450 CRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 509

Query: 599 CNTIENTGTKQSTCSPGDHIIEITEVE-EDLFPAETVELLREASAESDVGKSSESEFTQY 657
               E  G K+ T  P   + E+ + + + L P E+ E L   S +  +   SE     +
Sbjct: 510 ----EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE----DF 561

Query: 658 TTHHILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKS 717
           +      SL   +AK +   SE  +  P+S     T    A  +  S S++ +  +L K 
Sbjct: 562 SGPQNASSLKFEDAKLAAAISEVVSQTPAS-----TTQAGAPPRDTSQSDKDLDDALDKL 616

Query: 718 KDLLKQR 724
            D L QR
Sbjct: 617 SDSLGQR 623


>gi|27765085 calpastatin isoform b [Homo sapiens]
          Length = 686

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 104/487 (21%), Positives = 188/487 (38%), Gaps = 47/487 (9%)

Query: 260 VSGTPLQRIGSMSSVTSNK--ETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSP 317
           +SG P  +     S+T     E+ P  P  +S     L   +  L    ++TE+  ++  
Sbjct: 98  ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG-GPEETEEENTTYT 156

Query: 318 SPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSD 377
            P  E    ++ + IEE G +      K  +       L   KE ++G  A  ++    D
Sbjct: 157 GP--EVSDPMSSTYIEELGKREVTIPPKYRE-------LLAKKEGITGPPADSSKPIGPD 207

Query: 378 RISDEANSNFNQGTENEQSKETQSHESK---LGEESGIVESKL---DSDFNISSHSELEN 431
              D  +S+F  G+     K+T+  ES      + +G V S     +    +   +  + 
Sbjct: 208 DAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQ 267

Query: 432 SSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPH----VPATYQ 487
           + E  S  + T + EP   L + SI+ +   +    ++E+    +   P      PAT +
Sbjct: 268 ALEALSASLGTRQAEP--ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDK 325

Query: 488 LG---LTKSKRDHLLRTASQHSDSSGFAEDSTDCL---SLNHLQVQESLQAMGSSADSCD 541
            G   L + +     R+ S+  D      D ++C    S    + +ES  A  +      
Sbjct: 326 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAV 385

Query: 542 SETTVTSLGEDLATPTAQDQPYFNESEE---ESLVPLQKGLEKAAAVADKRKSGSQDFPQ 598
             T++ S+      P        +++ E   +SL   +   E    V DK K  +++  +
Sbjct: 386 CRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 445

Query: 599 CNTIENTGTKQSTCSPGDHIIEITEVE-EDLFPAETVELLREASAESDVGKSSESEFTQY 657
               E  G K+ T  P   + E+ + + + L P E+ E L   S +  +   SE     +
Sbjct: 446 ----EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE----DF 497

Query: 658 TTHHILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKS 717
           +      SL   +AK +   SE  +  P+S     T    A  +  S S++ +  +L K 
Sbjct: 498 SGPQNASSLKFEDAKLAAAISEVVSQTPAS-----TTQAGAPPRDTSQSDKDLDDALDKL 552

Query: 718 KDLLKQR 724
            D L QR
Sbjct: 553 SDSLGQR 559


>gi|109637753 calpastatin isoform a [Homo sapiens]
          Length = 791

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 104/487 (21%), Positives = 188/487 (38%), Gaps = 47/487 (9%)

Query: 260 VSGTPLQRIGSMSSVTSNK--ETDPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSP 317
           +SG P  +     S+T     E+ P  P  +S     L   +  L    ++TE+  ++  
Sbjct: 203 ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG-GPEETEEENTTYT 261

Query: 318 SPSAEKGKILNVSVIEESGNKNDQKSQKIMKKKESSSMLATVKEEVSGSSAAVTENADSD 377
            P  E    ++ + IEE G +      K  +       L   KE ++G  A  ++    D
Sbjct: 262 GP--EVSDPMSSTYIEELGKREVTIPPKYRE-------LLAKKEGITGPPADSSKPIGPD 312

Query: 378 RISDEANSNFNQGTENEQSKETQSHESK---LGEESGIVESKL---DSDFNISSHSELEN 431
              D  +S+F  G+     K+T+  ES      + +G V S     +    +   +  + 
Sbjct: 313 DAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQ 372

Query: 432 SSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEGEAPH----VPATYQ 487
           + E  S  + T + EP   L + SI+ +   +    ++E+    +   P      PAT +
Sbjct: 373 ALEALSASLGTRQAEP--ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDK 430

Query: 488 LG---LTKSKRDHLLRTASQHSDSSGFAEDSTDCL---SLNHLQVQESLQAMGSSADSCD 541
            G   L + +     R+ S+  D      D ++C    S    + +ES  A  +      
Sbjct: 431 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAV 490

Query: 542 SETTVTSLGEDLATPTAQDQPYFNESEE---ESLVPLQKGLEKAAAVADKRKSGSQDFPQ 598
             T++ S+      P        +++ E   +SL   +   E    V DK K  +++  +
Sbjct: 491 CRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 550

Query: 599 CNTIENTGTKQSTCSPGDHIIEITEVE-EDLFPAETVELLREASAESDVGKSSESEFTQY 657
               E  G K+ T  P   + E+ + + + L P E+ E L   S +  +   SE     +
Sbjct: 551 ----EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE----DF 602

Query: 658 TTHHILKSLASIEAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSLLKS 717
           +      SL   +AK +   SE  +  P+S     T    A  +  S S++ +  +L K 
Sbjct: 603 SGPQNASSLKFEDAKLAAAISEVVSQTPAS-----TTQAGAPPRDTSQSDKDLDDALDKL 657

Query: 718 KDLLKQR 724
            D L QR
Sbjct: 658 SDSLGQR 664


>gi|118498337 HECT domain containing 1 [Homo sapiens]
          Length = 2610

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 68/290 (23%), Positives = 114/290 (39%), Gaps = 51/290 (17%)

Query: 306  VDKTEKGESSSPSPSAEKGKILNVSVIEESGNKNDQKS----QKIMKKKESSSM----LA 357
            V +TE G SSS S S         ++  E+G++N ++       +    ESS++    ++
Sbjct: 1435 VPQTEVGSSSSASTS---------TLTAETGSENAERKLGPDSSVRTPGESSAISMGIVS 1485

Query: 358  TVKEEVSGSSAAVTENADSDRISDEANSN---------------FNQGTENEQSKETQSH 402
                +VS  S    + A S R    + SN                +    N  S+ET S 
Sbjct: 1486 VSSPDVSSVSELTNKEAASQRPLSSSASNRLSVSSLLAAGAPMSSSASVPNLSSRETSSL 1545

Query: 403  ESKLGEESGIVESKLDSDFNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQ 462
            ES +   + I  +   ++ N+S  S   N++ L    +ST         + P++    T 
Sbjct: 1546 ESFVRRVANIARTNATNNMNLSRSSSDNNTNTLGRNVMSTATSPLMGAQSFPNLTTPGTT 1605

Query: 463  QKDSFEMEEVQSTEGEAPHVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLN 522
               +     V S+   A    AT  L + +S  + L  T S  S SS   E  T      
Sbjct: 1606 STVTMSTSSVTSSSNVA---TATTVLSVGQSLSNTL--TTSLTSTSS---ESDTG----- 1652

Query: 523  HLQVQESLQAMGSSADSCDSETTVTSL--GEDLATPTAQDQPYFNESEEE 570
                QE+  ++    DSC + T +  L   EDL  P  +D    ++++E+
Sbjct: 1653 ----QEAEYSLYDFLDSCRASTLLAELDDDEDLPEPDEEDDENEDDNQED 1698


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.123    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,572,033
Number of Sequences: 37866
Number of extensions: 2404766
Number of successful extensions: 12732
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 345
Number of HSP's that attempted gapping in prelim test: 11633
Number of HSP's gapped (non-prelim): 1387
length of query: 1259
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1145
effective length of database: 13,930,794
effective search space: 15950759130
effective search space used: 15950759130
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.