BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|194363725 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform c [Homo sapiens] (1152 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|194363725 SWI/SNF-related matrix-associated actin-dependent r... 2338 0.0 gi|21237808 SWI/SNF-related matrix-associated actin-dependent re... 2285 0.0 gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 2171 0.0 gi|188536047 SWI/SNF-related matrix-associated actin-dependent r... 1337 0.0 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 76 2e-13 gi|160707881 formin 2 [Homo sapiens] 75 3e-13 gi|33356148 formin-like 1 [Homo sapiens] 75 3e-13 gi|7706501 WW domain binding protein 11 [Homo sapiens] 74 6e-13 gi|163965366 nascent polypeptide-associated complex alpha subuni... 72 2e-12 gi|57863314 vacuolar protein sorting 37C [Homo sapiens] 72 4e-12 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 70 9e-12 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 70 9e-12 gi|150170670 piccolo isoform 2 [Homo sapiens] 70 2e-11 gi|150378539 piccolo isoform 1 [Homo sapiens] 70 2e-11 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 69 2e-11 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 69 3e-11 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 69 3e-11 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 69 3e-11 gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens] 68 4e-11 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 67 1e-10 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 1e-10 gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 66 2e-10 gi|146134388 YLP motif containing 1 [Homo sapiens] 66 2e-10 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 4e-10 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 65 4e-10 gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 65 4e-10 gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 65 4e-10 gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 65 4e-10 gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 64 6e-10 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 64 6e-10 >gi|194363725 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform c [Homo sapiens] Length = 1152 Score = 2338 bits (6060), Expect = 0.0 Identities = 1152/1152 (100%), Positives = 1152/1152 (100%) Query: 1 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ Sbjct: 1 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60 Query: 61 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN Sbjct: 61 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120 Query: 121 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP Sbjct: 121 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180 Query: 181 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK Sbjct: 181 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240 Query: 241 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK Sbjct: 241 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300 Query: 301 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT Sbjct: 301 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360 Query: 361 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ Sbjct: 361 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420 Query: 421 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY Sbjct: 421 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480 Query: 481 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG Sbjct: 481 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540 Query: 541 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP Sbjct: 541 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600 Query: 601 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS Sbjct: 601 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660 Query: 661 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA Sbjct: 661 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720 Query: 721 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE Sbjct: 721 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780 Query: 781 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE Sbjct: 781 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840 Query: 841 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA Sbjct: 841 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900 Query: 901 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA Sbjct: 901 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960 Query: 961 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA Sbjct: 961 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020 Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS Sbjct: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080 Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP Sbjct: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140 Query: 1141 SPGTVTPVPPPQ 1152 SPGTVTPVPPPQ Sbjct: 1141 SPGTVTPVPPPQ 1152 >gi|21237808 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform b [Homo sapiens] Length = 1130 Score = 2285 bits (5921), Expect = 0.0 Identities = 1130/1152 (98%), Positives = 1130/1152 (98%), Gaps = 22/1152 (1%) Query: 1 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ Sbjct: 1 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60 Query: 61 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN Sbjct: 61 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120 Query: 121 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP Sbjct: 121 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180 Query: 181 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK Sbjct: 181 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240 Query: 241 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK Sbjct: 241 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300 Query: 301 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT Sbjct: 301 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360 Query: 361 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ Sbjct: 361 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420 Query: 421 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY Sbjct: 421 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480 Query: 481 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG Sbjct: 481 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540 Query: 541 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP Sbjct: 541 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600 Query: 601 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS Sbjct: 601 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660 Query: 661 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA Sbjct: 661 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720 Query: 721 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE Sbjct: 721 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780 Query: 781 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE Sbjct: 781 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840 Query: 841 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA Sbjct: 841 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900 Query: 901 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA Sbjct: 901 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960 Query: 961 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA Sbjct: 961 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020 Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS Sbjct: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080 Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140 PFPNQQTPPSMMPGAVPGSGHPGVA DPGTPLPPDPTAP Sbjct: 1081 PFPNQQTPPSMMPGAVPGSGHPGVA----------------------DPGTPLPPDPTAP 1118 Query: 1141 SPGTVTPVPPPQ 1152 SPGTVTPVPPPQ Sbjct: 1119 SPGTVTPVPPPQ 1130 >gi|21237805 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform a [Homo sapiens] Length = 1214 Score = 2171 bits (5626), Expect = 0.0 Identities = 1085/1141 (95%), Positives = 1086/1141 (95%), Gaps = 46/1141 (4%) Query: 1 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ Sbjct: 1 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60 Query: 61 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN Sbjct: 61 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120 Query: 121 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP Sbjct: 121 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180 Query: 181 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK Sbjct: 181 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240 Query: 241 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK Sbjct: 241 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300 Query: 301 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT Sbjct: 301 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360 Query: 361 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ Sbjct: 361 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420 Query: 421 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY Sbjct: 421 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480 Query: 481 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG Sbjct: 481 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540 Query: 541 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600 LVPLQPKTPQ QTSASQQMLNFPDKGKEKP Sbjct: 541 LVPLQPKTPQ-------------------------------QTSASQQMLNFPDKGKEKP 569 Query: 601 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS Sbjct: 570 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 629 Query: 661 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA Sbjct: 630 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 689 Query: 721 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE Sbjct: 690 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 749 Query: 781 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE Sbjct: 750 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 809 Query: 841 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA Sbjct: 810 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 869 Query: 901 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA Sbjct: 870 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 929 Query: 961 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA Sbjct: 930 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 989 Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS Sbjct: 990 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1049 Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140 PFPNQQTPPSMMPGAVPGSGHPGVA +P LP G P PP P AP Sbjct: 1050 PFPNQQTPPSMMPGAVPGSGHPGVAGNAPL--------------GLPF-GMPPPPPPPAP 1094 Query: 1141 S 1141 S Sbjct: 1095 S 1095 >gi|188536047 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c1 [Homo sapiens] Length = 1105 Score = 1337 bits (3461), Expect = 0.0 Identities = 706/1158 (60%), Positives = 852/1158 (73%), Gaps = 105/1158 (9%) Query: 4 RKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEV 63 R+KDGGP K++E+ +TV+Q D+VR+WLGK+YKKY+ A+ PTNK+L+ LVVQLLQFQE+ Sbjct: 32 RRKDGGPATKFWESPETVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDA 91 Query: 64 FGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEM 123 FGKHV+N TKLP KCF+DFKAGG+LCHIL AAYK+K++QGWRR+D QNPSRMDRNVEM Sbjct: 92 FGKHVTNPAFTKLPAKCFMDFKAGGALCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEM 151 Query: 124 FMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYPVPG 183 FM IEK+LVQNNCL+RPNI+L P+I+ KL KLKDIIKRHQGT T++K+ ASH +YP Sbjct: 152 FMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYSS 211 Query: 184 NLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWIL 243 + ++EEW+RPVM+++KQVL+HWG+YPDSYDTW+ +++++A +ED P PEKP KVH KWIL Sbjct: 212 SQDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWIL 271 Query: 244 DTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGG-NYKKRKRS 302 DTD FNEWMNEEDYEV++++ PVS R++IS K + V SP+ RRD+K N +KRK S Sbjct: 272 DTDIFNEWMNEEDYEVDENRKPVSFRQRISTKN-EEPVRSPE--RRDRKASANARKRKHS 328 Query: 303 PSPSP-TP-EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360 PSP P TP E++KK+ KKG ++ Y K + E+EQEDLTKDM++P+PVPN+EEV LPK Sbjct: 329 PSPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLTKDMEDPTPVPNIEEVVLPKN 388 Query: 361 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420 VN KKDSE+ PVKGGT+ DLDEQ++E++ GK++++ + KG+Q+++ DL EDNVTEQ Sbjct: 389 VNLKKDSENTPVKGGTVADLDEQDEETVTAGGKEDEDPA---KGDQSRSVDLGEDNVTEQ 445 Query: 421 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480 T+HIIIPSYA+WFDYN +H IERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY Sbjct: 446 TNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 505 Query: 481 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540 LTSTACRRNL GDVCA+MRVHAFLEQWGL+NYQVD ESRP MGPPPT HF+VLADTPSG Sbjct: 506 LTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSG 565 Query: 541 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600 LVPL ++PQ VP A+QQMLNFP+K KEKP Sbjct: 566 LVPLHLRSPQ--------------------VP------------AAQQMLNFPEKNKEKP 593 Query: 601 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660 D+QNFGLRTD+Y+KK + +KSK A SA REWTEQETLLLLEALEMYKDDWNKVSEHVGS Sbjct: 594 VDLQNFGLRTDIYSKKTL-AKSKGA-SAGREWTEQETLLLLEALEMYKDDWNKVSEHVGS 651 Query: 661 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720 RTQDECILHFLRLPIEDPYLE+S+ASLGPLAYQP+PFSQSGNPVMSTVAFLASVVDPRVA Sbjct: 652 RTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVA 711 Query: 721 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780 SAAAK+ALEEFS+++EEVP LVEAHV+KV+EAA+ +GK DP +GLESS IAGT DEPE Sbjct: 712 SAAAKAALEEFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPE 771 Query: 781 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840 ++E G +E ++E ++ E E + +E E E +K ++G++EK Sbjct: 772 KLE--GAEEEKMEADPDGQQPEKAENK-----VENETDEG---------DKAQDGENEKN 815 Query: 841 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGER-----KTKVERDIGEGNLSTAAAA 895 SEK D V + + E KE +E KE+ ++ ER K KVE +I EGN++TAAAA Sbjct: 816 SEKEQ-DSEVSEDTKSEEKETEEN--KELTDTCKERESDTGKKKVEHEISEGNVATAAAA 872 Query: 896 ALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQR 955 ALA+AA KAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDRE+EALE QR Sbjct: 873 ALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQR 932 Query: 956 QQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVH 1015 QQLL +RQ FHMEQLKYAE+RARQQ QQ H Q Q G + P GAAG P Sbjct: 933 QQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQ-HSGGPGLAPLGAAGHP--- 988 Query: 1016 GLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPG 1075 G P P + Q P PQPG +P PG Sbjct: 989 ----------------GMMPHQQPPPYPLMH-------HQMPPPHPPQPGQIPG----PG 1021 Query: 1076 PHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPG--TPL 1133 S P Q P M+P V + HP + +P + + GN+L PL P P Sbjct: 1022 ----SMMPGQHMPGRMIP-TVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPP 1076 Query: 1134 PPDPTAPSPGTVTPVPPP 1151 PP P P VPPP Sbjct: 1077 PPQQQPPPPPPADGVPPP 1094 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 76.3 bits (186), Expect = 2e-13 Identities = 59/171 (34%), Positives = 65/171 (38%), Gaps = 23/171 (13%) Query: 986 HQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIG 1045 HQQQQQPPP PP QP PP P H P P P S P + GP Sbjct: 66 HQQQQQPPPQQPPPQQP-PPHQPPPHPQPHQQQQPP----PPPQDSSKPVVAQGP----- 115 Query: 1046 QAGSTAGPQQQQPAGAPQPGAVPP--GVPPPGPHGPSPFPNQ---QTPPSMMPGAVPGSG 1100 G G PA + P A PP G PP GP+P P PP P P SG Sbjct: 116 --GPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSG 173 Query: 1101 HPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPP 1151 P Q+ P+A P P PG P P P G + P P Sbjct: 174 VPTTPPQAGGPPPP------PAAVPGPGPGPKQGPGPGGPKGGKMPGGPKP 218 Score = 69.3 bits (168), Expect = 2e-11 Identities = 61/183 (33%), Positives = 66/183 (36%), Gaps = 23/183 (12%) Query: 981 HFQQMHQQQQQPPPALPPGSQ-------------PIPPTGAAGPPAVHGLAVAPASVVPA 1027 H QQ QQPPP PP Q P PP ++ P G AP Sbjct: 66 HQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAP 125 Query: 1028 PAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGP--HGPSPFPNQ 1085 PA S APP + P GS GP P P + PPG PPP P G P Q Sbjct: 126 PASSSAPPAT--PPTSGAPPGSGPGP---TPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ 180 Query: 1086 QTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLP-PDPTAPSPGT 1144 P P AVPG G PG Q P G + P PG P P P G Sbjct: 181 AGGPPPPPAAVPGPG-PG-PKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGG 238 Query: 1145 VTP 1147 P Sbjct: 239 GEP 241 Score = 56.2 bits (134), Expect = 2e-07 Identities = 53/162 (32%), Positives = 57/162 (35%), Gaps = 35/162 (21%) Query: 1011 PPAVHGLAVAPASVVPAPAGSGA-PPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPP 1069 PP GL + P P SG PP P Q QQQ P P P PP Sbjct: 34 PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQ---------QQQQPPPQQPPPQQPPP 84 Query: 1070 GVPPPGPHGPSPFPNQQTPP----------SMMPGAVPGSGHPGVAAQSPAIVAAVQGNL 1119 PPP P P QQ PP + PG PG G A+ S Sbjct: 85 HQPPPHPQ---PHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGA 141 Query: 1120 LPSASPLPDPGTPLP---------PDPTAPSPGTVTPVPPPQ 1152 P + P P P TP P P PT PS G P PPQ Sbjct: 142 PPGSGPGPTP-TPPPAVTSAPPGAPPPTPPSSGV--PTTPPQ 180 Score = 53.5 bits (127), Expect = 1e-06 Identities = 49/158 (31%), Positives = 56/158 (35%), Gaps = 39/158 (24%) Query: 984 QMHQQQQQPPP---------ALPPGSQP----IPPTGAAGPPAVHGLAVAPA------SV 1024 Q HQQQQ PPP A PG P PP ++ PPA + AP + Sbjct: 92 QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTP 151 Query: 1025 VPAPAGSGAPPGS---LGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP------------- 1068 P PA + APPG+ PS + AG PA P PG P Sbjct: 152 TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGK 211 Query: 1069 -PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSG---HP 1102 PG P PG P P G P G HP Sbjct: 212 MPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP 249 Score = 49.7 bits (117), Expect = 2e-05 Identities = 37/125 (29%), Positives = 45/125 (36%), Gaps = 8/125 (6%) Query: 1033 APPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP--- 1089 +PP +G ++ G G G +P P P PPP P P Q PP Sbjct: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQ 92 Query: 1090 ---SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVT 1146 P P V AQ P V G+ P++S P P P PG T Sbjct: 93 PHQQQQPPPPPQDSSKPVVAQGPGPAPGV-GSAPPASSSAPPATPPTSGAPPGSGPGP-T 150 Query: 1147 PVPPP 1151 P PPP Sbjct: 151 PTPPP 155 Score = 45.1 bits (105), Expect = 4e-04 Identities = 36/108 (33%), Positives = 40/108 (37%), Gaps = 12/108 (11%) Query: 992 PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPA-GSGAPPGSLGPS--EQIGQAG 1048 PPP P P P A GPP P + VP P G PG GP + G Sbjct: 165 PPPTPPSSGVPTTPPQAGGPPP-------PPAAVPGPGPGPKQGPGPGGPKGGKMPGGPK 217 Query: 1049 STAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQ--QTPPSMMPG 1094 GP P G P+P G P G P+ Q Q PP PG Sbjct: 218 PGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPG 265 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 75.5 bits (184), Expect = 3e-13 Identities = 59/171 (34%), Positives = 70/171 (40%), Gaps = 22/171 (12%) Query: 992 PPPALP-PGSQPIPPTGAAG---PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047 PPP LP G P PP AG PP + G+ + P +P G+G PP P I Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP---GAGIPPPPPLPGAGIPPP 1132 Query: 1048 GSTAGPQQQQPAGAPQPGAVPP------GVPPPGPHGPSPFPNQQTPPSMMPGA--VPGS 1099 G P P+ G PP G+PPP P + P PP +PG P Sbjct: 1133 PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP----PPPPLPGVGIPPPP 1188 Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150 PGV P + G +P PLP G P P P P PGT P PP Sbjct: 1189 PLPGVGIPPP---PPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPP 1236 Score = 74.7 bits (182), Expect = 5e-13 Identities = 62/192 (32%), Positives = 76/192 (39%), Gaps = 41/192 (21%) Query: 991 QPPPA-----LPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP------GSLG 1039 QPPP LPP P+P G PP + G + P +P G+G PP ++ Sbjct: 898 QPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLP---GAGIPPPPPLPGAAIP 954 Query: 1040 PSEQIGQAGSTAGPQQQQPAGAPQPGAVP-PGVPPPGP------HGPSPFPNQQTPPSMM 1092 P + AG P AG P P +P G+PPP P P P P PP Sbjct: 955 PPPPLPGAGIPL-PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--- 1010 Query: 1093 PGAVPGSG------HPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP-------DPTA 1139 P +PG+G PG P + G +P PLP G P PP P Sbjct: 1011 PPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1067 Query: 1140 PSPGTVTPVPPP 1151 P PG P PPP Sbjct: 1068 PLPGAGIPPPPP 1079 Score = 72.8 bits (177), Expect = 2e-12 Identities = 63/197 (31%), Positives = 73/197 (37%), Gaps = 43/197 (21%) Query: 992 PPPALP-PGSQPIPPTGAAG---PPAVHGLAVAPASVVPAPA--------GSGAPPGSLG 1039 PPP LP G P+PP AG PP + G A+ P +P G+G PP Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981 Query: 1040 PSEQIGQAGSTAGPQQQQPAGAPQPGAVPP------GVPPPGP------HGPSPFPNQQT 1087 P I G P P G PP G+PPP P P P P Sbjct: 982 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1041 Query: 1088 PPSMMPGAVPGSG------HPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP------ 1135 PP P +PG+G PG P + G +P PLP G P PP Sbjct: 1042 PP---PPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1095 Query: 1136 -DPTAPSPGTVTPVPPP 1151 P P PG P PPP Sbjct: 1096 IPPPPPLPGVGIPPPPP 1112 Score = 72.0 bits (175), Expect = 3e-12 Identities = 60/182 (32%), Positives = 71/182 (39%), Gaps = 35/182 (19%) Query: 992 PPPALP----PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047 PPP LP P P+P G PP + G + P +P G+G PP P I Sbjct: 977 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---GAGIPPPPPLPGAGIPPP 1033 Query: 1048 GSTAGPQQQQPAGAPQPGAVPP------GVPPPGP------HGPSPFPNQQTPPSMMPGA 1095 G P P G PP G+PPP P P P P PP P Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---PPP 1090 Query: 1096 VPGSGHP------GVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149 +PG+G P GV P + G +P PLP G +PP P P PG P P Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPP---PLPGAGIPPPPPLPGAG--IPPPP--PLPGAGIPPP 1143 Query: 1150 PP 1151 PP Sbjct: 1144 PP 1145 Score = 70.5 bits (171), Expect = 9e-12 Identities = 61/189 (32%), Positives = 71/189 (37%), Gaps = 38/189 (20%) Query: 992 PPPALPPGS-QPIPPTGAAG---PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047 PPP LP + P PP AG PP + G + P +P G+G PP P I Sbjct: 944 PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP---GAGIPPPPPLPGAGIPPP 1000 Query: 1048 GSTAGPQQQQPAGAPQPGAVPP------GVPPPGP------HGPSPFPNQQTPPSMMPGA 1095 G P P G PP G+PPP P P P P PP P Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---PPP 1057 Query: 1096 VPGSG------HPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP-------DPTAPSP 1142 +PG+G PG P + G +P PLP G P PP P P P Sbjct: 1058 LPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1114 Query: 1143 GTVTPVPPP 1151 G P PPP Sbjct: 1115 GAGIPPPPP 1123 Score = 60.5 bits (145), Expect = 9e-09 Identities = 50/157 (31%), Positives = 59/157 (37%), Gaps = 50/157 (31%) Query: 992 PPPALP----PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047 PPP LP P P+P G PP + G + P +P G+G PP Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP---GAGIPP------------ 1175 Query: 1048 GSTAGPQQQQPAGAPQPGAVP-PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAA 1106 P G P P +P G+PP P P P PP P +PG G P Sbjct: 1176 -----PPPLPGVGIPPPPPLPGVGIPP-----PPPLPGAGIPP---PPPLPGMGIP---- 1218 Query: 1107 QSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPG 1143 PA A PLP PGT +PP P P G Sbjct: 1219 --PA-----------PAPPLPPPGTGIPPPPLLPVSG 1242 Score = 52.4 bits (124), Expect = 2e-06 Identities = 80/333 (24%), Positives = 124/333 (37%), Gaps = 56/333 (16%) Query: 844 SDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVK 903 S G P P++E ++ + E V E+ +R V++++ + +K Sbjct: 624 SMGPPSKPPDEEHRLEDAETESQSAVSETPQKRSDAVQKEVVD---------------MK 668 Query: 904 AKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQ 963 ++ A V ++ +++ L T++ +LE R + L+T + + LE + A Sbjct: 669 SEGQATVIQQLEQTIEDL--RTKIAELE---RQYPALDTEVASGHQGLE---NGVTASGD 720 Query: 964 AFHMEQLKYAEMRARQQHFQQMHQQQQQPPP-----ALPP-----GSQPIPPTGAAGPPA 1013 +E L+ E R + Q P LPP G P PP +GP Sbjct: 721 VC-LEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQT 779 Query: 1014 VHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPG--- 1070 + S++ +P S P++ I Q P AG QPG+ PP Sbjct: 780 KF---CSEISLIVSPRRISVQLDSHQPTQSISQPPPP--PSLLWSAGQGQPGSQPPHSIS 834 Query: 1071 --VPPPGPHG-PSPFPNQQTPPSMMP-------GAVPGSGHPGVAAQSPAIVAAVQGNLL 1120 H S F N PS P ++PG G V P + L Sbjct: 835 TEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGM--VPPPPPPLPGMTVPTLP 892 Query: 1121 PSASPLPDP--GTPLPPDPTAPSPGTVTPVPPP 1151 +A P P P GT + P P P PG P PPP Sbjct: 893 STAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPP 925 Score = 45.8 bits (107), Expect = 2e-04 Identities = 52/224 (23%), Positives = 81/224 (36%), Gaps = 37/224 (16%) Query: 954 QRQQLLAD-RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPP 1012 +++ LL+D +QA ++Q +QQ Q+ QQQQ L +P P A P Sbjct: 191 EQEDLLSDIQQAIRLQQ--------QQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQ 242 Query: 1013 AVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAG---STAGPQQQQPAGAPQPGAVP- 1068 L + + P+ G+G PGS + + + + ++P P PG +P Sbjct: 243 PGAFLGLDRFLLGPS-GGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPV 301 Query: 1069 ------PGVPPPGPHGPS----PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGN 1118 P P PS PFP V G+G + A A +G+ Sbjct: 302 SEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGS 361 Query: 1119 LLPSASPLPDPGTPLP-----------PDPTAPSPGTVTPVPPP 1151 P P+ G P P AP+ ++ P P Sbjct: 362 --PGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 75.5 bits (184), Expect = 3e-13 Identities = 72/253 (28%), Positives = 92/253 (36%), Gaps = 55/253 (21%) Query: 920 ALLVETQMKKLEIKLRHFEELET----IMDREREALEYQRQQLLADRQAFHMEQLKYAEM 975 ALL +T+ K L H EEL+ + +R R+A ++ + + + + Sbjct: 386 ALLEDTETKNAV--LEHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQARKELETL 443 Query: 976 RARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAA----------------GPPAVHGLAV 1019 R R M ++ P P P + P P+ GP + + Sbjct: 444 RERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEI 503 Query: 1020 APASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQ-QPAGAPQPGAVPPGVPPPGPHG 1078 P +V G PG T P PA P PGA PP PPP P Sbjct: 504 LPVAVATPSGGDAPTPGV-----------PTGSPSPDLAPAAEPAPGAAPPP-PPPLPGL 551 Query: 1079 PSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPT 1138 PSP Q+ PPS P A P G P P A PLP P PP P Sbjct: 552 PSP---QEAPPSAPPQAPPLPGSPEP----------------PPAPPLPGD-LPPPPPPP 591 Query: 1139 APSPGTVTPVPPP 1151 P PGT PVPPP Sbjct: 592 PPPPGTDGPVPPP 604 Score = 48.5 bits (114), Expect = 4e-05 Identities = 37/110 (33%), Positives = 46/110 (41%), Gaps = 13/110 (11%) Query: 999 GSQPIP--PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQ 1056 G P P PTG+ P +APA+ PAP + PP L +A +A PQ Sbjct: 514 GDAPTPGVPTGSPSPD------LAPAAE-PAPGAAPPPPPPLPGLPSPQEAPPSAPPQAP 566 Query: 1057 QPAGAPQPGAVPPGV----PPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP 1102 G+P+P PP PPP P P P + PP P P G P Sbjct: 567 PLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPP 616 Score = 46.2 bits (108), Expect = 2e-04 Identities = 36/121 (29%), Positives = 43/121 (35%), Gaps = 14/121 (11%) Query: 992 PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051 P P L P ++P P PP + GL + AP + PGS P G Sbjct: 526 PSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLP 585 Query: 1052 GPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAV---PGSGHPGVAAQS 1108 P P G VPP PPP P PP P A+ PGV A+ Sbjct: 586 PPPPPPPPPPGTDGPVPPPPPPPPP-----------PPGGPPDALGRRDSELGPGVKAKK 634 Query: 1109 P 1109 P Sbjct: 635 P 635 Score = 40.0 bits (92), Expect = 0.013 Identities = 25/64 (39%), Positives = 29/64 (45%), Gaps = 9/64 (14%) Query: 991 QPPPALP-PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049 +PPPA P PG P PP PP G V P P PPG GP + +G+ S Sbjct: 573 EPPPAPPLPGDLPPPPPPPPPPPGTDG------PVPPPPPPPPPPPG--GPPDALGRRDS 624 Query: 1050 TAGP 1053 GP Sbjct: 625 ELGP 628 Score = 38.1 bits (87), Expect = 0.049 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 15/121 (12%) Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPF---PNQQTPPSMMPGAV- 1096 S +G + P++ PA +P A+ V G P ++P AV Sbjct: 450 STAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVA 509 Query: 1097 -PGSGH---PGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPD-PTAPSPGTVTPVPPP 1151 P G PGV SP+ +L P+A P P P PP P PSP P PP Sbjct: 510 TPSGGDAPTPGVPTGSPS------PDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPP 563 Query: 1152 Q 1152 Q Sbjct: 564 Q 564 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 74.3 bits (181), Expect = 6e-13 Identities = 88/328 (26%), Positives = 136/328 (41%), Gaps = 39/328 (11%) Query: 830 EKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNL 889 ++G + D SE DG P + + + + K ES+G+ V RD GE + Sbjct: 242 QRGHDDDVSSTSE-DDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEF--VHRDNGERDN 298 Query: 890 STAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDRERE 949 + + L+ V+ + +K K++ L T ++ + +++ E I + RE Sbjct: 299 NEEKKSGLS---VRFADMPGKSRKKKKNMKEL---TPLQAMMLRMAGQE----IPEEGRE 348 Query: 950 ALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQ--------QQQQPPPALPPGSQ 1001 E+ D AE ++++QH ++ H QQQ PP ++PP Sbjct: 349 VEEFSEDDDEDDSDDSE------AEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402 Query: 1002 PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA 1061 PP GPP + G AP P P +G PPG + + G + P Sbjct: 403 QAPPM--PGPPPL-GPPPAPPLRPPGPP-TGLPPGPPPGAPPFLRPPGMPGLRGPLPRLL 458 Query: 1062 PQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLP 1121 P PG PPG PP P GP P PP P +P PG+ P + ++ L+P Sbjct: 459 P-PGP-PPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGM---MRPPLVP 513 Query: 1122 SASPLPDPGTPLPPDPTAPSPGTVTPVP 1149 P P PG PP P P+PG ++ P Sbjct: 514 PLGPAP-PGL-FPPAP-LPNPGVLSAPP 538 Score = 62.8 bits (151), Expect = 2e-09 Identities = 73/311 (23%), Positives = 116/311 (37%), Gaps = 58/311 (18%) Query: 828 DEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEG 887 D++K + + +++KSDG+ +G E V ++ GER E+ G Sbjct: 263 DQDKHDDSTDDSDTDKSDGE-----------SDGDEFVHRD----NGERDNNEEKKSG-- 305 Query: 888 NLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDRE 947 LS A + K K++ +++ L A+++ +++ + R EE D + Sbjct: 306 -LSVRFADMPGKSRKKKKNM-----KELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDED 359 Query: 948 -REALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPP--GSQPIP 1004 + E ++Q ++ H + A + + Q Q PP PP G P P Sbjct: 360 DSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAP 419 Query: 1005 PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAG---- 1060 P GPP GL P P PG GP ++ G G P G Sbjct: 420 PLRPPGPPT--GLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPG 477 Query: 1061 ---APQPGAVPPGVPPPGPHG-PSPFPNQQTP---------------PSMMPGAVPGSGH 1101 P P PP +PPP P G P P P P P+ +P + Sbjct: 478 LPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLP-------N 530 Query: 1102 PGVAAQSPAIV 1112 PGV + P ++ Sbjct: 531 PGVLSAPPNLI 541 Score = 31.6 bits (70), Expect = 4.5 Identities = 37/162 (22%), Positives = 59/162 (36%), Gaps = 29/162 (17%) Query: 922 LVETQMKKLEIKLRH-FEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRAR-Q 979 L E +K KLR FE + + ++E + + ++L +++Y + RA+ Sbjct: 73 LNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKL----------EVEYEQKRAQLS 122 Query: 980 QHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLG 1039 Q+F + Q ++P P P+ + P PP L Sbjct: 123 QYFDAVKNAQHVEVESIPLPDMPHAPSNIL--------------IQDIPLPGAQPPSILK 168 Query: 1040 PSEQIGQAGSTAGPQQQQPAGAPQ--PGAVPPGVPPPGPHGP 1079 + G G P+ PG PPG PPPGP P Sbjct: 169 KTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPG-PPPGPPPP 209 Score = 31.6 bits (70), Expect = 4.5 Identities = 29/80 (36%), Positives = 31/80 (38%), Gaps = 14/80 (17%) Query: 1073 PPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTP 1132 P PH PS Q P +PGA P S +A P A S PL G P Sbjct: 142 PDMPHAPSNILIQDIP---LPGAQPPSILKKTSAYGPPTRAV-------SILPLLGHGVP 191 Query: 1133 -LPPDPTAPSPGTVTPVPPP 1151 LPP P P P PPP Sbjct: 192 RLPPGRKPPGP---PPGPPP 208 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 72.4 bits (176), Expect = 2e-12 Identities = 59/178 (33%), Positives = 70/178 (39%), Gaps = 40/178 (22%) Query: 992 PPPALPPGSQPIP----PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047 PP A PP + P P A PPA + P+P G+ PP + PS + Sbjct: 942 PPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK---- 997 Query: 1048 GSTAGPQQQQPAGAPQPGAVPPGVPPPGPHG---PSPFP-NQQTPPSMMPGAVPGSGHPG 1103 GP P GAP PP V PP P G +PFP TPP+ P + G Sbjct: 998 ---GGPATPSPKGAP----TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG----- 1045 Query: 1104 VAAQSPAIVAAVQGNLLPSASPLPDP----------GTPLPPDPTAPSP--GTVTPVP 1149 SPA +G A+ LP P G P PP T PSP G TP P Sbjct: 1046 ----SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099 Score = 70.5 bits (171), Expect = 9e-12 Identities = 58/177 (32%), Positives = 71/177 (40%), Gaps = 29/177 (16%) Query: 992 PPPALP--PGSQPIPPTGAAGPPAVHGLAVAPASV---------VPAPAGSGAPPGSLGP 1040 PP P P + P P G P+ G PA+ P+P G+ P + P Sbjct: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226 Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGP----SPFPNQQTPPSMMPG-A 1095 S + G A P P GAP A P P GP P +P P TPPS+ G A Sbjct: 1227 SPK----GGLATP---SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279 Query: 1096 VPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152 P P A +PA+V P+ S P G P PP T PSP PPP+ Sbjct: 1280 TP----PHKGAPNPAVVTPPSPKGGPATS--PPKGAPTPPAATPPSPKGSPGTPPPK 1330 Score = 68.2 bits (165), Expect = 4e-11 Identities = 63/190 (33%), Positives = 76/190 (40%), Gaps = 37/190 (19%) Query: 992 PPPALPPGSQPIP----PTGAAGPPAVHGLAV--APASVVPAPAGSGAPPGSLGPSEQIG 1045 PP A PP + P P GA PPAV + +PA+ P P G+ PP + PS + Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT-PFPKGASTPPAATPPSPKGS 1046 Query: 1046 QAGS-----------------TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS----PFPN 1084 A + GP GAP P A P P GP PS P P Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106 Query: 1085 QQTPPSMMPGAV--PGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSP 1142 TPPS G P G P A +P + +G L A+P P G P P T PSP Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATP---PSPKGGL---ATP-PPKGAPTTPAATPPSP 1159 Query: 1143 GTVTPVPPPQ 1152 PPP+ Sbjct: 1160 KGGLATPPPK 1169 Score = 64.3 bits (155), Expect = 6e-10 Identities = 56/167 (33%), Positives = 65/167 (38%), Gaps = 24/167 (14%) Query: 997 PPGSQPIPPTGA-AGPPAVHGLAVAPASVVPAPAGSGAPPGSLG-PSEQIGQAGST-AGP 1053 PP + P P G+ A P G PA+ +P+P G A P G P+ S GP Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094 Query: 1054 QQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP----SMMPGAVPGSGHPGVAAQSP 1109 P GAP +PP PP P G TPP P A P S G+A P Sbjct: 1095 ATPSPKGAP----MPPAATPPSPKG-----GLATPPHKGAPTTPAATPPSPKGGLATPPP 1145 Query: 1110 AIVAAVQGNLLPS-----ASPLPDPGTPLPPDPTAPSP--GTVTPVP 1149 PS A+P P G P P T PSP G TP P Sbjct: 1146 KGAPTTPAATPPSPKGGLATP-PPKGAPTTPAATPPSPKGGLATPSP 1191 Score = 62.8 bits (151), Expect = 2e-09 Identities = 62/178 (34%), Positives = 74/178 (41%), Gaps = 25/178 (14%) Query: 992 PPPALPPGSQ---PIPPTGAAGP-----PAVHGLAVAP--ASVVPAPAGSGAPPGSLG-P 1040 PP P S P P G A P PA+ + +P A PAP G A P G P Sbjct: 881 PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAP 940 Query: 1041 SEQIGQAGS-TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS----PFPNQQTPPSMMPGA 1095 + S GP P AP P A P P GP PS P P TPPS P Sbjct: 941 TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS--PKG 998 Query: 1096 VPGSGHPGVAAQSPAIV-AAVQGNLLPSASPLPDPGTPLPPDPTAPSP---GTVTPVP 1149 P + P A PA+ + +G+ P+A+P P G PP T PSP TP+P Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGS--PAATPFP-KGASTPPAATPPSPKGSPAATPLP 1053 Score = 62.8 bits (151), Expect = 2e-09 Identities = 59/184 (32%), Positives = 69/184 (37%), Gaps = 27/184 (14%) Query: 986 HQQQQQPPPALPP----GSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS 1041 H+ P A PP G PP GA PA + P P G+ P + PS Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181 Query: 1042 EQIGQAGSTAGPQQQQPAGAP-QPGAVPP----GVPPPGPHGPSPFPNQQTPPSMMPG-A 1095 + G A P P GAP P A PP G+ P P G +P TPPS G A Sbjct: 1182 PK----GGLATP---SPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLA 1233 Query: 1096 VPG-SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTP--------LPPDPTAPSPGTVT 1146 P G P A +P P +P P TP PP AP+P VT Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293 Query: 1147 PVPP 1150 P P Sbjct: 1294 PPSP 1297 Score = 61.2 bits (147), Expect = 5e-09 Identities = 55/186 (29%), Positives = 67/186 (36%), Gaps = 31/186 (16%) Query: 992 PPPALPPGSQPIP----PTGAAGPPAV--------------HGLAVAPASVVPAPAGSGA 1033 PP A PP + P P GA PPA G PA+ P+P G A Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141 Query: 1034 PPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSM 1091 P P + + P + P P P P PP P G P+ + P+ Sbjct: 1142 TP----PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT- 1196 Query: 1092 MPGAVPGSGHPGVAAQSPAIVAAVQGNLLPS-----ASPLPDPGTPLPPDPTAPSPGTVT 1146 P A P S G+A SP PS A+P P G P P T PSP Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGP 1255 Query: 1147 PVPPPQ 1152 PPP+ Sbjct: 1256 ATPPPK 1261 Score = 60.1 bits (144), Expect = 1e-08 Identities = 54/171 (31%), Positives = 66/171 (38%), Gaps = 30/171 (17%) Query: 993 PPALPPGSQPIPPTGAAGPPAV------HGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQ 1046 PP+ G PP GA PPA GLA P P PA PP G Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA-VVTPPSPKG------- 1299 Query: 1047 AGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAA 1106 GP P GAP P A P P P P P TPP++ P + G+ P + A Sbjct: 1300 -----GPATSPPKGAPTPPAATPPSPKGSPGTPPP-KGAPTPPAVTPPSPKGT--PTLPA 1351 Query: 1107 QSPAIVAAVQGNLLPSASPLPDPGTPLP-----PDPTAPSPGTVTPVPPPQ 1152 +P ++ G PS+ P P P P T PSP +P P+ Sbjct: 1352 TTP---SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399 Score = 59.7 bits (143), Expect = 2e-08 Identities = 57/180 (31%), Positives = 69/180 (38%), Gaps = 24/180 (13%) Query: 992 PPPALP-PGSQPIPPT--GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA- 1047 P LP P P P+ GA PPA + P+P G+ PP + PS + G A Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119 Query: 1048 ----GSTAGPQQQQPA-----GAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSMMPGAV 1096 G+ P P+ P P P P PP P G P + P+ P A Sbjct: 1120 PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT-TPAAT 1178 Query: 1097 PGSGHPGVAAQSPAIVAAVQGNLLPS-----ASPLPDPGTPLPPDPTAPSP--GTVTPVP 1149 P S G+A SP PS A+P P G P P T PSP G TP P Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGLATPSP 1237 Score = 58.2 bits (139), Expect = 5e-08 Identities = 54/183 (29%), Positives = 69/183 (37%), Gaps = 27/183 (14%) Query: 988 QQQQPPPALPPGSQPIPPTGAAGPPAVHGLA----VAPASVVPAPAGSGAPPGSLGP--- 1040 Q + PA P P GA P AV L+ P P P+ P GP Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903 Query: 1041 -----------SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP 1089 S +A +T P+ + +P+ PP PP P G P+ + P Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963 Query: 1090 SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDP-GTPLPPDPT-APSPGTVTP 1147 + P A P S G A SP +G P A+ P P G P P P AP+P VTP Sbjct: 964 TP-PAATPPSPKGGPATPSP------KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP 1016 Query: 1148 VPP 1150 P Sbjct: 1017 PSP 1019 Score = 56.6 bits (135), Expect = 1e-07 Identities = 58/163 (35%), Positives = 64/163 (39%), Gaps = 28/163 (17%) Query: 1004 PPT--GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA 1061 PPT G+AGP G +P S V A S P SL +T P P GA Sbjct: 808 PPTKKGSAGPDTPIGNLSSPVSPVEA---SFLPENSLSFQGSKDSPATTHSPTPPSPKGA 864 Query: 1062 PQPGAV----PPGVPPPGPHGPS------PFPNQ--QTP-PSMMPGAVPGSGHPGVAAQS 1108 P P AV P GV P P+ PFP + TP P P S P A + Sbjct: 865 PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARAT 924 Query: 1109 PAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSP--GTVTPVP 1149 PA ASP P G P PP T PSP G TP P Sbjct: 925 PAPKGI-------PASPSP-KGAPTPPAATPPSPKGGPATPSP 959 Score = 56.6 bits (135), Expect = 1e-07 Identities = 50/173 (28%), Positives = 63/173 (36%), Gaps = 18/173 (10%) Query: 992 PPPALPPGSQPIP----PTGAAGPPAV-----HGLAVAPASVVPAPAGSGAPPGSLGPSE 1042 PP A PP + P P GA PPAV G PA+ + G P GP+ Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371 Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPP--GPHGPSPFPNQQTPPSMMPGAVPGSG 1100 GP P +P+ G P +P P P P+ P P G+ Sbjct: 1372 PAATPSHKGGPAMTPP--SPKRG---PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA 1426 Query: 1101 HPGVAAQSPAIVAAVQGNLLPSAS-PLPDPGTPLPP-DPTAPSPGTVTPVPPP 1151 P +P V V P+ S P P TP DPT P+ +P PP Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479 Score = 55.5 bits (132), Expect = 3e-07 Identities = 53/175 (30%), Positives = 68/175 (38%), Gaps = 22/175 (12%) Query: 997 PPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQ 1056 PP + P P G+ G P G PA P+P G+ P + PS + G ++ Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT-PSSKGGPTTPSSKEGPT 1370 Query: 1057 QPAGAPQ----PGAVPPGVPPPGPHGPSPFPNQQTPPSMMP------GAVP----GSGHP 1102 PA P P PP P GP PSP T P+++P A P G+ P Sbjct: 1371 PPAATPSHKGGPAMTPPS-PKRGPAIPSP-KGDPTSPAVIPLSPKKAPATPVTREGAATP 1428 Query: 1103 GVAAQSPAIVAAVQGNLLPSAS-PLPDPGTPLPP-DPTAPS---PGTVTPVPPPQ 1152 +P V V P+ S P P TP DPT P+ P P P Q Sbjct: 1429 SKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483 Score = 50.4 bits (119), Expect = 9e-06 Identities = 46/170 (27%), Positives = 62/170 (36%), Gaps = 15/170 (8%) Query: 994 PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSL--GPSEQIGQAGSTA 1051 P LP + P P A + A PAP G+ P + P E S Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524 Query: 1052 GP--------QQQQPAG-APQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP 1102 P ++ PA AP+ +PP + P P P + P+ P + S P Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT-PSSKEASSPP 1583 Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPDPG-TPLPPDPTAPSP--GTVTPVP 1149 V + + + L+P A P P P PP T PSP G TP P Sbjct: 1584 AVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633 Score = 49.7 bits (117), Expect = 2e-05 Identities = 50/159 (31%), Positives = 60/159 (37%), Gaps = 33/159 (20%) Query: 994 PALP-PGSQPIPPTG--AAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050 PA+P P P P+ A+ PPAV A P+P PP PS Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGA---PSPKELLIPPAVTSPS--------- 1609 Query: 1051 AGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPA 1110 P AP P AV P P GP P+P +PP + P ++ S SPA Sbjct: 1610 -------PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP-VTPSSLKDS------PTSPA 1655 Query: 1111 IVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149 V G +P AS G P PTA V P P Sbjct: 1656 SVTCKMGATVPQAS----KGLPAKKGPTALKEVLVAPAP 1690 Score = 47.0 bits (110), Expect = 1e-04 Identities = 50/200 (25%), Positives = 75/200 (37%), Gaps = 42/200 (21%) Query: 993 PPALPP----GSQPIPPTGAAGP--PAVHGLAVAPASVVPAPAGSGAPP----GSLGPSE 1042 PPA P G PP+ GP P+ G +PA + +P + A P G+ PS+ Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK 1430 Query: 1043 -----------QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSM 1091 + +A +T+ P+ + + P V PP P P P P +Q S Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP-PAP-KQVATSS 1488 Query: 1092 MPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTP------------------- 1132 P P + P A PA++ + + + S DP P Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548 Query: 1133 LPPDPTAPSPGTVTPVPPPQ 1152 +PP T PSP +P P+ Sbjct: 1549 IPPAMTVPSPKKTPAIPTPK 1568 Score = 37.0 bits (84), Expect = 0.11 Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 21/174 (12%) Query: 991 QPPPALPPGSQPIP---PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047 QP P LPP P P P AA + +P+++ P P S G + +G A Sbjct: 40 QPGPTLPPPCSPAPQQCPLSAANQASPF---PSPSTIASTPLEVPFPQSSSGTALPLGTA 96 Query: 1048 --GSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMM---PGAVPGSG-- 1100 T P P +P A+ + P G P+ P +++ P +V S Sbjct: 97 PEAPTFLPNLIGPPISPAALALASPMIAPTLKGT---PSSSAPLALVALAPHSVQKSSAF 153 Query: 1101 HPGVAAQSPAIVAAVQGNLLPSASPL--PDPGTPL--PPDPTAPSPGTVTPVPP 1150 P + P++ A G+++ ++P+ +P T L P P+P TP PP Sbjct: 154 PPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNP-KGTPSPP 206 Score = 37.0 bits (84), Expect = 0.11 Identities = 46/177 (25%), Positives = 64/177 (36%), Gaps = 30/177 (16%) Query: 992 PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051 PP PPG++ + G + A+ +A +P +G+ A S G + + S Sbjct: 740 PPAGTPPGTKKVD--GISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPL 797 Query: 1052 G----PQQQQP------AGAPQP-GAVPPGVPPPG----PHGPSPFPNQQTPPSMMPGAV 1096 G PQ ++P AG P G + V P P F + P+ Sbjct: 798 GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857 Query: 1097 PGS--GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSP--GTVTPVP 1149 P S G P +A +P L P LP TP P P P G TP P Sbjct: 858 PPSPKGAPTPSAVTP---------LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP 905 Score = 35.8 bits (81), Expect = 0.24 Identities = 51/192 (26%), Positives = 64/192 (33%), Gaps = 39/192 (20%) Query: 992 PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVV-----PAPAGSGAPPGSLGP------ 1040 P P P S P+ P+ P +PASV P S P GP Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPT------SPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684 Query: 1041 -------SEQIGQAGSTAGPQQQQ-----PAGAPQPGAVPPGVPPPGPHGPSPF-PNQQT 1087 S I A + GPQ ++ P P P A P P+P P Q+ Sbjct: 1685 LVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744 Query: 1088 PPSMMPG-----AVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPD--PTAP 1140 G + G P + S + AA +LP P PP P AP Sbjct: 1745 SSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP 1804 Query: 1141 SPGTVTPVPPPQ 1152 SP V +PP Q Sbjct: 1805 SP--VPTLPPKQ 1814 >gi|57863314 vacuolar protein sorting 37C [Homo sapiens] Length = 355 Score = 71.6 bits (174), Expect = 4e-12 Identities = 59/174 (33%), Positives = 71/174 (40%), Gaps = 26/174 (14%) Query: 987 QQQQQPPPALPPGSQPIPPTGA--AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQI 1044 ++Q QPP A+PP P P+ + GP A L AP VV P+ P G P+ Q+ Sbjct: 191 EEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQL 250 Query: 1045 G---QAGSTAGPQQQQPAGAPQP----GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVP 1097 G AG + PQ+ P P GA PG P G PSP QQ+P G P Sbjct: 251 GPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPP 310 Query: 1098 GSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPL-PPDPTAPSPGTVTPVPP 1150 P LPS P P PL PP P P+P P PP Sbjct: 311 YPIQP----------------QLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPP 348 Score = 46.2 bits (108), Expect = 2e-04 Identities = 42/137 (30%), Positives = 49/137 (35%), Gaps = 31/137 (22%) Query: 992 PPPALPPGSQP---------IPPTGAAGPPAVHGLAVAPA-SVVPAPAGSGAPPGSLGPS 1041 PP P SQP P GP G + +P S+ P P G P G+ GP Sbjct: 224 PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPG 283 Query: 1042 EQI--GQAGSTAGPQQQ-------------QPAGAPQPGAVPPGVPPPGPHGPSPFPNQQ 1086 + G+A S PQQ QP PG P VP P+ P P P Sbjct: 284 YPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYG 343 Query: 1087 TPPSMMPGAVPGSGHPG 1103 PP PG PG Sbjct: 344 FPPP------PGPAWPG 354 Score = 36.2 bits (82), Expect = 0.18 Identities = 45/140 (32%), Positives = 55/140 (39%), Gaps = 20/140 (14%) Query: 1029 AGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP----PGVP-PPGPHG---PS 1080 AG PP P + Q +Q QP A P +P P +P P HG P+ Sbjct: 167 AGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPA 226 Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPD-PGTPL----PP 1135 PFP + PS G + G +P A P A + S P P PGTP+ P Sbjct: 227 PFP-VVSQPSFYSGPL-GPTYP-AAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPG 283 Query: 1136 DP----TAPSPGTVTPVPPP 1151 P APSPG P P Sbjct: 284 YPLRGGRAPSPGYPQQSPYP 303 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 70.5 bits (171), Expect = 9e-12 Identities = 61/173 (35%), Positives = 66/173 (38%), Gaps = 22/173 (12%) Query: 989 QQQPPPALPPGSQPIPPT----GAAGPPAVHGLA--VAPASVVPAPAGSGAP--PGSLGP 1040 Q P P PG Q P G GPP + GL + P G P PG LGP Sbjct: 422 QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481 Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSG 1100 G+ G Q P G P G + PPG GP P PP PG G Sbjct: 482 K---GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGF-----PGIG 533 Query: 1101 HPGVAA-QSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152 PGVA P G L P P PG P PP P P P + P PPPQ Sbjct: 534 KPGVAGLHGP---PGKPGALGPQGQP-GLPGPPGPPGPPGP-PAVMPPTPPPQ 581 Score = 58.5 bits (140), Expect = 3e-08 Identities = 57/189 (30%), Positives = 70/189 (37%), Gaps = 30/189 (15%) Query: 991 QPPPALPPGSQPIP-PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049 QP P G + +P P G GP G + A V P G PPG +G +G+ G Sbjct: 218 QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG-LPGVGKPGV 276 Query: 1050 TAGPQQQQPAGAP----QPGAV----------PPGVPPPGPHGPSPFPNQQTPPSMM--- 1092 T P Q P G P +PG PPG+P G G P Q P Sbjct: 277 TGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQ 336 Query: 1093 -------PGAVPGSGHPGV-AAQSPAIVAAVQGNLLP--SASPLPDPGTPLPPDPTAPSP 1142 P +PG G PG + + V G L P P+ PG PP P Sbjct: 337 GLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPG-LP 395 Query: 1143 GTVTPVPPP 1151 G P+ PP Sbjct: 396 GIPGPMGPP 404 Score = 53.5 bits (127), Expect = 1e-06 Identities = 51/182 (28%), Positives = 62/182 (34%), Gaps = 23/182 (12%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLG---PSEQIGQA 1047 +P P PPG +P G G G P P G PG++G +IGQ Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQK 184 Query: 1048 GSTAGPQQQQPAGAPQPGAVP-------PGVP----PPGPHGPSPFPNQQ-------TPP 1089 G P G P P +P PG+P P G GP P Q Sbjct: 185 GEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG 244 Query: 1090 SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149 MPGA G PG+ P + G P + P P PL PG P+ Sbjct: 245 FGMPGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302 Query: 1150 PP 1151 P Sbjct: 303 VP 304 Score = 50.1 bits (118), Expect = 1e-05 Identities = 49/147 (33%), Positives = 57/147 (38%), Gaps = 12/147 (8%) Query: 988 QQQQPPPALPP---GSQPIPPTGAAGP---PAVHGLAVAPASVVPAPAGSGAPPGSLGPS 1041 Q Q PP +P S PI P G GP P + G P P AG PPG G Sbjct: 491 QGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGAL 550 Query: 1042 EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPP-GPHGPS-PFPNQQTPPSMMPGAVPGS 1099 GQ G P P G P P AV P PPP G + P P GA G Sbjct: 551 GPQGQPGLPGPPG---PPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGK 607 Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPL 1126 + G A + PA A + P +P+ Sbjct: 608 -NGGPAYEMPAFTAELTAPFPPVGAPV 633 Score = 45.8 bits (107), Expect = 2e-04 Identities = 44/158 (27%), Positives = 54/158 (34%), Gaps = 14/158 (8%) Query: 994 PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGP 1053 P P G G GPP + G+ G G PG+LGP G+ G P Sbjct: 327 PGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPR---GEKGPIGAP 383 Query: 1054 QQQQPAGAPQPGAVPPGVPP------PGPHGPSPFPNQQTPPSMM--PGAVPGSGHPGVA 1105 P G P +P + P PGP G Q PP PG G PG Sbjct: 384 GIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFL 443 Query: 1106 AQ-SPAIVAAVQGNLLP--SASPLPDPGTPLPPDPTAP 1140 + P + + G + P A PG P P P Sbjct: 444 GEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481 Score = 32.3 bits (72), Expect = 2.7 Identities = 49/180 (27%), Positives = 61/180 (33%), Gaps = 25/180 (13%) Query: 991 QPPPALPPGSQPIPPTGAAGPP---AVHGLAVAPASVVPAPAGSGAP--PGSLGPSEQIG 1045 Q PP +PP P G P A GLA+ + G P P + + Sbjct: 39 QIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGK-EMPHLQYGKEYPHLPQYMKEIQPAP 97 Query: 1046 QAGSTAGPQ------------QQQPAGAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSM 1091 + G A P+ +Q P G P P P PG+P G G P Q P + Sbjct: 98 RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV 157 Query: 1092 MPGAVPG-SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150 +PG G PG A Q P+ PG PP P PG P P Sbjct: 158 GKPGMPGMPGKPGAMGMPGAKGEIGQKG---EIGPMGIPGPQGPPGPHG-LPGIGKPGGP 213 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 70.5 bits (171), Expect = 9e-12 Identities = 61/173 (35%), Positives = 66/173 (38%), Gaps = 22/173 (12%) Query: 989 QQQPPPALPPGSQPIPPT----GAAGPPAVHGLA--VAPASVVPAPAGSGAP--PGSLGP 1040 Q P P PG Q P G GPP + GL + P G P PG LGP Sbjct: 422 QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481 Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSG 1100 G+ G Q P G P G + PPG GP P PP PG G Sbjct: 482 K---GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGF-----PGIG 533 Query: 1101 HPGVAA-QSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152 PGVA P G L P P PG P PP P P P + P PPPQ Sbjct: 534 KPGVAGLHGP---PGKPGALGPQGQP-GLPGPPGPPGPPGP-PAVMPPTPPPQ 581 Score = 58.5 bits (140), Expect = 3e-08 Identities = 57/189 (30%), Positives = 70/189 (37%), Gaps = 30/189 (15%) Query: 991 QPPPALPPGSQPIP-PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049 QP P G + +P P G GP G + A V P G PPG +G +G+ G Sbjct: 218 QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG-LPGVGKPGV 276 Query: 1050 TAGPQQQQPAGAP----QPGAV----------PPGVPPPGPHGPSPFPNQQTPPSMM--- 1092 T P Q P G P +PG PPG+P G G P Q P Sbjct: 277 TGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQ 336 Query: 1093 -------PGAVPGSGHPGV-AAQSPAIVAAVQGNLLP--SASPLPDPGTPLPPDPTAPSP 1142 P +PG G PG + + V G L P P+ PG PP P Sbjct: 337 GLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPG-LP 395 Query: 1143 GTVTPVPPP 1151 G P+ PP Sbjct: 396 GIPGPMGPP 404 Score = 53.5 bits (127), Expect = 1e-06 Identities = 51/182 (28%), Positives = 62/182 (34%), Gaps = 23/182 (12%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLG---PSEQIGQA 1047 +P P PPG +P G G G P P G PG++G +IGQ Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQK 184 Query: 1048 GSTAGPQQQQPAGAPQPGAVP-------PGVP----PPGPHGPSPFPNQQ-------TPP 1089 G P G P P +P PG+P P G GP P Q Sbjct: 185 GEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG 244 Query: 1090 SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149 MPGA G PG+ P + G P + P P PL PG P+ Sbjct: 245 FGMPGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302 Query: 1150 PP 1151 P Sbjct: 303 VP 304 Score = 50.1 bits (118), Expect = 1e-05 Identities = 49/147 (33%), Positives = 57/147 (38%), Gaps = 12/147 (8%) Query: 988 QQQQPPPALPP---GSQPIPPTGAAGP---PAVHGLAVAPASVVPAPAGSGAPPGSLGPS 1041 Q Q PP +P S PI P G GP P + G P P AG PPG G Sbjct: 491 QGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGAL 550 Query: 1042 EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPP-GPHGPS-PFPNQQTPPSMMPGAVPGS 1099 GQ G P P G P P AV P PPP G + P P GA G Sbjct: 551 GPQGQPGLPGPPG---PPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGK 607 Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPL 1126 + G A + PA A + P +P+ Sbjct: 608 -NGGPAYEMPAFTAELTAPFPPVGAPV 633 Score = 45.8 bits (107), Expect = 2e-04 Identities = 44/158 (27%), Positives = 54/158 (34%), Gaps = 14/158 (8%) Query: 994 PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGP 1053 P P G G GPP + G+ G G PG+LGP G+ G P Sbjct: 327 PGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPR---GEKGPIGAP 383 Query: 1054 QQQQPAGAPQPGAVPPGVPP------PGPHGPSPFPNQQTPPSMM--PGAVPGSGHPGVA 1105 P G P +P + P PGP G Q PP PG G PG Sbjct: 384 GIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFL 443 Query: 1106 AQ-SPAIVAAVQGNLLP--SASPLPDPGTPLPPDPTAP 1140 + P + + G + P A PG P P P Sbjct: 444 GEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481 Score = 32.3 bits (72), Expect = 2.7 Identities = 49/180 (27%), Positives = 61/180 (33%), Gaps = 25/180 (13%) Query: 991 QPPPALPPGSQPIPPTGAAGPP---AVHGLAVAPASVVPAPAGSGAP--PGSLGPSEQIG 1045 Q PP +PP P G P A GLA+ + G P P + + Sbjct: 39 QIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGK-EMPHLQYGKEYPHLPQYMKEIQPAP 97 Query: 1046 QAGSTAGPQ------------QQQPAGAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSM 1091 + G A P+ +Q P G P P P PG+P G G P Q P + Sbjct: 98 RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV 157 Query: 1092 MPGAVPG-SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150 +PG G PG A Q P+ PG PP P PG P P Sbjct: 158 GKPGMPGMPGKPGAMGMPGAKGEIGQKG---EIGPMGIPGPQGPPGPHG-LPGIGKPGGP 213 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 69.7 bits (169), Expect = 2e-11 Identities = 60/187 (32%), Positives = 70/187 (37%), Gaps = 30/187 (16%) Query: 990 QQP----PPALPPGSQ--PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPG------- 1036 QQP PP PPG+ P P G A PPA + P+S P P PPG Sbjct: 344 QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403 Query: 1037 SLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP-PGVPPPGPHGPSPFPNQQT-------- 1087 GP++ Q T P QQP G P P P P GP P QQ Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQP-GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462 Query: 1088 ------PPSMMPG-AVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140 PPS +PG A P PG A P + + S P P P P P+ Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522 Query: 1141 SPGTVTP 1147 PG+ P Sbjct: 523 QPGSTKP 529 Score = 65.1 bits (157), Expect = 4e-10 Identities = 62/190 (32%), Positives = 72/190 (37%), Gaps = 31/190 (16%) Query: 990 QQPPPALPPGSQP---IPPTGAAGPPA-----VHGLAVAPASVVPA--PAGSGAPPGS-L 1038 QQP P PP QP G A PPA LA P +V P P G+ PP L Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366 Query: 1039 GPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-----PPPGPHGP------SPFPNQQT 1087 GP++ Q + P +QP P+ A PPGV PGP P +P P Q Sbjct: 367 GPAKPPAQQTGSEKPSSEQPG--PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424 Query: 1088 PPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPD----PTAPSPG 1143 P P PG V P + A Q P + G PP P P P Sbjct: 425 PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG--PGKTSAQQTGPTKPPSQLPGPAKPPPQ 482 Query: 1144 TVTPV-PPPQ 1152 P PPPQ Sbjct: 483 QPGPAKPPPQ 492 Score = 63.9 bits (154), Expect = 8e-10 Identities = 58/182 (31%), Positives = 67/182 (36%), Gaps = 29/182 (15%) Query: 990 QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASV-----------VPAP-AGSGA---- 1033 QQP PA PP Q P A P + A AP +PA AG G Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462 Query: 1034 ------PPGSL-GPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-PPPGPHGPSPFPNQ 1085 PP L GP++ Q A P QQP A P P PPP GP+ Q Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522 Query: 1086 QTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTV 1145 Q + P PGS P SPA +A Q S P+ G+ P P SP Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ-----STKPVSQTGSGKPLQPPTVSPSAK 577 Query: 1146 TP 1147 P Sbjct: 578 QP 579 Score = 60.1 bits (144), Expect = 1e-08 Identities = 62/204 (30%), Positives = 73/204 (35%), Gaps = 46/204 (22%) Query: 992 PPPALPPGSQPIP-------------PTGAAGPPA-----VHGLAVAPASVVP--APAGS 1031 P P+ PP QP P G A PPA LA P +V P P G+ Sbjct: 299 PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT 358 Query: 1032 GAPPGS-LGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-----PPPGPHGP------ 1079 PP LGP++ Q + P +QP P+ A PPGV PGP P Sbjct: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQP--GPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416 Query: 1080 SPFPNQQTP----------PSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDP 1129 +P P Q P P+ P PG G P +A Q S LP P Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476 Query: 1130 GTPLP--PDPTAPSPGTVTPVPPP 1151 P P P P P P PP Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPP 500 Score = 52.4 bits (124), Expect = 2e-06 Identities = 53/160 (33%), Positives = 60/160 (37%), Gaps = 39/160 (24%) Query: 990 QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049 QQP PA PP QP G+A PP+ P S P P PG PS Q Q GS Sbjct: 482 QQPGPAKPPPQQP----GSAKPPSQQ-----PGSTKPPP----QQPGPAKPSPQ--QPGS 526 Query: 1050 TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSP 1109 T P Q QPG+ P P P PS S P + GSG P Q P Sbjct: 527 TKPPSQ-------QPGSAKPSAQQPSPAKPS------AQQSTKPVSQTGSGKP---LQPP 570 Query: 1110 AIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149 + PSA P G P P + + VP Sbjct: 571 TV--------SPSAKQPPSQGLPKTICPLCNTTELLLHVP 602 Score = 40.8 bits (94), Expect = 0.007 Identities = 42/141 (29%), Positives = 58/141 (41%), Gaps = 17/141 (12%) Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080 PAS +P SG+P S P++ S++ QP P P PP PPP P P Sbjct: 2372 PASQLP----SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP--PPPPPPPPP 2425 Query: 1081 PFPNQQTP-PSMMPGAVPGSGHPGVAAQSPAI--------VAAVQGNLLPSASPLPDPGT 1131 P P +P P+++P P V +P A ++ N LP Sbjct: 2426 PLPPPTSPKPTILPKKKLTVASP-VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPP 2484 Query: 1132 PLPPDPTA-PSPGTVTPVPPP 1151 P+PP P++ PS T P P Sbjct: 2485 PVPPKPSSIPSGLVFTHRPEP 2505 Score = 40.0 bits (92), Expect = 0.013 Identities = 42/167 (25%), Positives = 60/167 (35%), Gaps = 15/167 (8%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP--------GSLGPSE 1042 QPPP PP P PP PP + +++P + A P ++ E Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE 2463 Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPG---PHGPSPFPNQQTPPSMMPGAVPGS 1099 S P + AP P P P G H P P P ++P + Sbjct: 2464 TTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTT 2523 Query: 1100 GHPGVAAQSP---AIVAAVQGNLLPSAS-PLPDPGTPLPPDPTAPSP 1142 P P ++ +++ NL+ SA LP P +PL P SP Sbjct: 2524 QKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSP 2570 Score = 38.1 bits (87), Expect = 0.049 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 17/120 (14%) Query: 984 QMHQQQQQPPPALPPGSQP---IPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040 Q +++ PP ++P PPTG P + +P PA GP Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-------DSKAIPRPASDSKIISHPGP 836 Query: 1041 S------EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTP-PSMMP 1093 S +Q+ P++ Q +P+P A P P P GP P Q P P P Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896 Score = 33.9 bits (76), Expect = 0.92 Identities = 39/150 (26%), Positives = 51/150 (34%), Gaps = 27/150 (18%) Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPP----------- 1069 P+SV+ P E GQ P Q P+G+P ++P Sbjct: 2344 PSSVIALPMKEQLSTTYFTSGETFGQEK----PASQLPSGSPSVSSLPAKPRPFFRSSSL 2399 Query: 1070 --GVPPPGPHGPSPFPNQQTPPSMMPG-AVPGSGHPGVAAQSPAIVAAVQGNLLPSASPL 1126 PP P P P P PP P P S P + + VA+ + +A+PL Sbjct: 2400 DISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP----VTTATPL 2455 Query: 1127 PDPGTPLPPDPTAPSPG-----TVTPVPPP 1151 D T L S G T PPP Sbjct: 2456 FDAVTTLETTAVLRSNGLPVTRICTTAPPP 2485 Score = 32.3 bits (72), Expect = 2.7 Identities = 35/163 (21%), Positives = 63/163 (38%), Gaps = 22/163 (13%) Query: 717 PRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAG--- 773 P S E+ + E + + E +++ +E K T K D + SS Sbjct: 1438 PHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS 1497 Query: 774 ------TTSDEP-ERIEESGNDE----------ARVEGQATDEKKEPKEPREGGGAIEEE 816 TT EP + +EES E V ++DE K+ E +G G E+ Sbjct: 1498 EFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ--EDSQGSGEEEDF 1555 Query: 817 AKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPK 859 +++ E ++ G E D ++ + + +K++E K Sbjct: 1556 IRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETK 1598 Score = 31.2 bits (69), Expect = 5.9 Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 4/72 (5%) Query: 1085 QQTPPSMMPGAVPG----SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140 Q+ P S +P P P +S ++ + Q P P P P P PP P P Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428 Query: 1141 SPGTVTPVPPPQ 1152 P + P P+ Sbjct: 2429 PPTSPKPTILPK 2440 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 69.7 bits (169), Expect = 2e-11 Identities = 60/187 (32%), Positives = 70/187 (37%), Gaps = 30/187 (16%) Query: 990 QQP----PPALPPGSQ--PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPG------- 1036 QQP PP PPG+ P P G A PPA + P+S P P PPG Sbjct: 344 QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403 Query: 1037 SLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP-PGVPPPGPHGPSPFPNQQT-------- 1087 GP++ Q T P QQP G P P P P GP P QQ Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQP-GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462 Query: 1088 ------PPSMMPG-AVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140 PPS +PG A P PG A P + + S P P P P P+ Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522 Query: 1141 SPGTVTP 1147 PG+ P Sbjct: 523 QPGSTKP 529 Score = 65.1 bits (157), Expect = 4e-10 Identities = 62/190 (32%), Positives = 72/190 (37%), Gaps = 31/190 (16%) Query: 990 QQPPPALPPGSQP---IPPTGAAGPPA-----VHGLAVAPASVVPA--PAGSGAPPGS-L 1038 QQP P PP QP G A PPA LA P +V P P G+ PP L Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366 Query: 1039 GPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-----PPPGPHGP------SPFPNQQT 1087 GP++ Q + P +QP P+ A PPGV PGP P +P P Q Sbjct: 367 GPAKPPAQQTGSEKPSSEQPG--PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424 Query: 1088 PPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPD----PTAPSPG 1143 P P PG V P + A Q P + G PP P P P Sbjct: 425 PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG--PGKTSAQQTGPTKPPSQLPGPAKPPPQ 482 Query: 1144 TVTPV-PPPQ 1152 P PPPQ Sbjct: 483 QPGPAKPPPQ 492 Score = 63.9 bits (154), Expect = 8e-10 Identities = 58/182 (31%), Positives = 67/182 (36%), Gaps = 29/182 (15%) Query: 990 QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASV-----------VPAP-AGSGA---- 1033 QQP PA PP Q P A P + A AP +PA AG G Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462 Query: 1034 ------PPGSL-GPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-PPPGPHGPSPFPNQ 1085 PP L GP++ Q A P QQP A P P PPP GP+ Q Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522 Query: 1086 QTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTV 1145 Q + P PGS P SPA +A Q S P+ G+ P P SP Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ-----STKPVSQTGSGKPLQPPTVSPSAK 577 Query: 1146 TP 1147 P Sbjct: 578 QP 579 Score = 60.1 bits (144), Expect = 1e-08 Identities = 62/204 (30%), Positives = 73/204 (35%), Gaps = 46/204 (22%) Query: 992 PPPALPPGSQPIP-------------PTGAAGPPA-----VHGLAVAPASVVP--APAGS 1031 P P+ PP QP P G A PPA LA P +V P P G+ Sbjct: 299 PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT 358 Query: 1032 GAPPGS-LGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-----PPPGPHGP------ 1079 PP LGP++ Q + P +QP P+ A PPGV PGP P Sbjct: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQP--GPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416 Query: 1080 SPFPNQQTP----------PSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDP 1129 +P P Q P P+ P PG G P +A Q S LP P Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476 Query: 1130 GTPLP--PDPTAPSPGTVTPVPPP 1151 P P P P P P PP Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPP 500 Score = 52.4 bits (124), Expect = 2e-06 Identities = 53/160 (33%), Positives = 60/160 (37%), Gaps = 39/160 (24%) Query: 990 QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049 QQP PA PP QP G+A PP+ P S P P PG PS Q Q GS Sbjct: 482 QQPGPAKPPPQQP----GSAKPPSQQ-----PGSTKPPP----QQPGPAKPSPQ--QPGS 526 Query: 1050 TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSP 1109 T P Q QPG+ P P P PS S P + GSG P Q P Sbjct: 527 TKPPSQ-------QPGSAKPSAQQPSPAKPS------AQQSTKPVSQTGSGKP---LQPP 570 Query: 1110 AIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149 + PSA P G P P + + VP Sbjct: 571 TV--------SPSAKQPPSQGLPKTICPLCNTTELLLHVP 602 Score = 40.8 bits (94), Expect = 0.007 Identities = 42/141 (29%), Positives = 58/141 (41%), Gaps = 17/141 (12%) Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080 PAS +P SG+P S P++ S++ QP P P PP PPP P P Sbjct: 2372 PASQLP----SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP--PPPPPPPPP 2425 Query: 1081 PFPNQQTP-PSMMPGAVPGSGHPGVAAQSPAI--------VAAVQGNLLPSASPLPDPGT 1131 P P +P P+++P P V +P A ++ N LP Sbjct: 2426 PLPPPTSPKPTILPKKKLTVASP-VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPP 2484 Query: 1132 PLPPDPTA-PSPGTVTPVPPP 1151 P+PP P++ PS T P P Sbjct: 2485 PVPPKPSSIPSGLVFTHRPEP 2505 Score = 40.0 bits (92), Expect = 0.013 Identities = 42/167 (25%), Positives = 60/167 (35%), Gaps = 15/167 (8%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP--------GSLGPSE 1042 QPPP PP P PP PP + +++P + A P ++ E Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE 2463 Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPG---PHGPSPFPNQQTPPSMMPGAVPGS 1099 S P + AP P P P G H P P P ++P + Sbjct: 2464 TTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTT 2523 Query: 1100 GHPGVAAQSP---AIVAAVQGNLLPSAS-PLPDPGTPLPPDPTAPSP 1142 P P ++ +++ NL+ SA LP P +PL P SP Sbjct: 2524 QKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSP 2570 Score = 38.1 bits (87), Expect = 0.049 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 17/120 (14%) Query: 984 QMHQQQQQPPPALPPGSQP---IPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040 Q +++ PP ++P PPTG P + +P PA GP Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-------DSKAIPRPASDSKIISHPGP 836 Query: 1041 S------EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTP-PSMMP 1093 S +Q+ P++ Q +P+P A P P P GP P Q P P P Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896 Score = 33.9 bits (76), Expect = 0.92 Identities = 39/150 (26%), Positives = 51/150 (34%), Gaps = 27/150 (18%) Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPP----------- 1069 P+SV+ P E GQ P Q P+G+P ++P Sbjct: 2344 PSSVIALPMKEQLSTTYFTSGETFGQEK----PASQLPSGSPSVSSLPAKPRPFFRSSSL 2399 Query: 1070 --GVPPPGPHGPSPFPNQQTPPSMMPG-AVPGSGHPGVAAQSPAIVAAVQGNLLPSASPL 1126 PP P P P P PP P P S P + + VA+ + +A+PL Sbjct: 2400 DISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP----VTTATPL 2455 Query: 1127 PDPGTPLPPDPTAPSPG-----TVTPVPPP 1151 D T L S G T PPP Sbjct: 2456 FDAVTTLETTAVLRSNGLPVTRICTTAPPP 2485 Score = 32.3 bits (72), Expect = 2.7 Identities = 35/163 (21%), Positives = 63/163 (38%), Gaps = 22/163 (13%) Query: 717 PRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAG--- 773 P S E+ + E + + E +++ +E K T K D + SS Sbjct: 1438 PHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS 1497 Query: 774 ------TTSDEP-ERIEESGNDE----------ARVEGQATDEKKEPKEPREGGGAIEEE 816 TT EP + +EES E V ++DE K+ E +G G E+ Sbjct: 1498 EFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ--EDSQGSGEEEDF 1555 Query: 817 AKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPK 859 +++ E ++ G E D ++ + + +K++E K Sbjct: 1556 IRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETK 1598 Score = 31.2 bits (69), Expect = 5.9 Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 4/72 (5%) Query: 1085 QQTPPSMMPGAVPG----SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140 Q+ P S +P P P +S ++ + Q P P P P P PP P P Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428 Query: 1141 SPGTVTPVPPPQ 1152 P + P P+ Sbjct: 2429 PPTSPKPTILPK 2440 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 69.3 bits (168), Expect = 2e-11 Identities = 105/475 (22%), Positives = 171/475 (36%), Gaps = 70/475 (14%) Query: 731 FSKMKEEVPTALVEAHVRKVEEAAKVTG---KADPAFGLESSGIAGTTSDEPERIEE--- 784 F+KM +E +V V KV +D + S + T E ER + Sbjct: 454 FAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAE 513 Query: 785 ---------------SGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDE 829 S + + + + D+K++ KE + +EE K K E P K Sbjct: 514 LQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKT 573 Query: 830 EKGKEGDS-----EKESEKSDGDPIVDPEKEKEPK----EGQEEVLKEVVESEGERKTKV 880 +K +S E KS P + E+E + K E + ++ ++ + GE+ +V Sbjct: 574 KKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRV 633 Query: 881 ERDIG--EGNLSTAAAAALAAAAVKAKHLAAVE-ERKIKSLVALLVETQMKKLEI----- 932 I E +L + + K E ER + S + + Q +K+++ Sbjct: 634 VHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSS 693 Query: 933 KLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQP 992 K++ F E+ E + + + ++ + + K R +++H HQQ QQ Sbjct: 694 KMKGFSSSESESSSESSSSDSED----SETEMAPKSKKKGHPGREQKKHHHHHHQQMQQA 749 Query: 993 PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVP--------APAGSGAPPGSLGPSEQI 1044 P +P QP PP PP P P APA +PP + + Sbjct: 750 PAPVP--QQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV 807 Query: 1045 ------GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQ--TPPSMMPGAV 1096 G G Q PQP +PP +P P H P NQ P + A+ Sbjct: 808 LEPQLPGSVFDPIGHFTQPILHLPQP-ELPPHLPQPPEHSTPPHLNQHAVVSPPALHNAL 866 Query: 1097 P---------GSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSP 1142 P + P A+ PA+ A+ L P+ P L D P+P Sbjct: 867 PQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAP 921 Score = 40.8 bits (94), Expect = 0.007 Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 13/148 (8%) Query: 1016 GLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPG 1075 G A S VP + PP + P +T P V VPP Sbjct: 187 GTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246 Query: 1076 PHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQG-------NLLPSASPLPD 1128 P P P Q PP P P HP + A +P V +G + P+ + Sbjct: 247 LQTPPPVPPQPQPPPA-PAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHE 305 Query: 1129 PGTPLPPDPTAPSPG----TVTPVPPPQ 1152 P + LPP+P G + PV PP+ Sbjct: 306 PPS-LPPEPKTTKLGQRRESSRPVKPPK 332 Score = 40.4 bits (93), Expect = 0.010 Identities = 55/212 (25%), Positives = 70/212 (33%), Gaps = 41/212 (19%) Query: 981 HFQQ--MHQQQQQPPPALP-PGSQPIPPT----GAAGPPAVHG-LAVAP-------ASVV 1025 HF Q +H Q + PP LP P PP PPA+H L P A++ Sbjct: 822 HFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALP 881 Query: 1026 PAPAGSGAPPGSLGPSEQIGQAGSTAGPQ----QQQPAGAP-----------QPGAVPPG 1070 P PA A +L + + Q PQ ++P P Q V P Sbjct: 882 PKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941 Query: 1071 VP----------PPGPHGPSPFPN-QQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNL 1119 P PP P P P P+ QQ P P P Q V Sbjct: 942 TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQP 1001 Query: 1120 LPSASPLPDPGTPLPPDPTAPSPGTVTPVPPP 1151 + ++ + P P P P PG P P P Sbjct: 1002 MQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQP 1033 Score = 38.9 bits (89), Expect = 0.028 Identities = 42/155 (27%), Positives = 50/155 (32%), Gaps = 26/155 (16%) Query: 981 HFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040 H Q QQQPPP PP QP P PP P L P Sbjct: 963 HPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR---------------------PVHLQP 1001 Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSG 1100 + PQ QQP P PG P PPP P P P +G Sbjct: 1002 MQFSTHIQQPPPPQGQQPP-HPPPGQQP---PPPQPAKPQQVIQHHHSPRHHKSDPYSTG 1057 Query: 1101 HPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP 1135 H A SP ++ + Q + S + P + P Sbjct: 1058 HLR-EAPSPLMIHSPQMSQFQSLTHQSPPQQNVQP 1091 Score = 38.5 bits (88), Expect = 0.037 Identities = 34/151 (22%), Positives = 65/151 (43%), Gaps = 18/151 (11%) Query: 846 GDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAA-----LAAA 900 G P++ P ++ P G + K+ + E + ++D+ N+ + A+ ++ Sbjct: 1158 GRPVIRPPEQNAPPPGAPD--KDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSS 1215 Query: 901 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960 K+ + + R+ A E + K L+ + H E +E+E L +R + Sbjct: 1216 TAKSSSDSFEQFRR----AAREKEEREKALKAQAEHAE-------KEKERLRQERMRSRE 1264 Query: 961 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQ 991 D A + + E R RQ+ QQ Q+QQQ Sbjct: 1265 DEDALEQARRAHEEARRRQEQQQQQRQEQQQ 1295 Score = 37.7 bits (86), Expect = 0.063 Identities = 28/92 (30%), Positives = 33/92 (35%), Gaps = 1/92 (1%) Query: 1060 GAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIV-AAVQGN 1118 G + G PGV + P Q P P V + HP A IV V Sbjct: 182 GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTV 241 Query: 1119 LLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150 + P P P P P P AP+P V PP Sbjct: 242 VPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPP 273 Score = 37.7 bits (86), Expect = 0.063 Identities = 58/208 (27%), Positives = 80/208 (38%), Gaps = 40/208 (19%) Query: 955 RQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAV 1014 +QQ + H++ ++++ H QQ Q Q PP PPG QP PP A P V Sbjct: 987 QQQHQPPPRPVHLQPMQFST------HIQQPPPPQGQQPPHPPPGQQP-PPPQPAKPQQV 1039 Query: 1015 HGLAVAPASVVPAPAGSG----APPGSLGPSEQIGQAGS---------TAGPQQQQPAGA 1061 +P P +G AP + S Q+ Q S P++Q+ A Sbjct: 1040 IQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAA 1099 Query: 1062 ----PQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQG 1117 PQP V V H P ++ PS+ P HP +I A V Sbjct: 1100 SVVQPQPLVV---VKEEKIHSPI-IRSEPFSPSLRP---EPPKHP------ESIKAPVHL 1146 Query: 1118 NLLPSASPLPDPGTPL--PPDPTAPSPG 1143 P P+ D G P+ PP+ AP PG Sbjct: 1147 PQRPEMKPV-DVGRPVIRPPEQNAPPPG 1173 Score = 36.6 bits (83), Expect = 0.14 Identities = 47/172 (27%), Positives = 54/172 (31%), Gaps = 40/172 (23%) Query: 992 PPPALPPGSQP-------IPPTGAAGPPAVHGLAVAPASVVPAPAGSGA----------- 1033 P PA PP P +P A PP V + PAP + Sbjct: 882 PKPARPPAVSPALTQTPLLPQPPMAQPPQV----LLEDEEPPAPPLTSMQMQLYLQQLQK 937 Query: 1034 --PPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSM 1091 PP L PS ++ P P+ Q PP PPP P P P QQ P Sbjct: 938 VQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPP---PQQQHQPPP 994 Query: 1092 MPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSAS--PLPDPG-TPLPPDPTAP 1140 P V Q +Q P P P PG P PP P P Sbjct: 995 RP----------VHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKP 1036 Score = 30.8 bits (68), Expect = 7.8 Identities = 28/123 (22%), Positives = 48/123 (39%), Gaps = 10/123 (8%) Query: 282 NSPDSDRRDKKGGNYKKRKRSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTK 341 N P +DKK +K KR E KK AK+ P K+ + +++ Sbjct: 534 NKPKKKEKDKKEKKKEKHKRK---EEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAP 590 Query: 342 DMDEPSPVPNVEEVTLPKTVNTKK------DSESAP-VKGGTMTDLDEQEDESMETTGKD 394 +P P EE K ++ ++ D P K G + + + + S++ + D Sbjct: 591 MKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPD 650 Query: 395 EDE 397 E E Sbjct: 651 EIE 653 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 68.9 bits (167), Expect = 3e-11 Identities = 78/290 (26%), Positives = 113/290 (38%), Gaps = 54/290 (18%) Query: 903 KAKHLAAVEERKIKSLVALLVETQ--MKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960 K++ AA E+K+ S + E Q MKK+E FE+ + E++AL ++QQ+ Sbjct: 467 KSEAKAAELEKKLDSELTARHELQVEMKKME---SDFEQKLQDLQGEKDALHSEKQQIAT 523 Query: 961 DRQAFHMEQLKYA--------EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPT----GA 1008 ++Q E + E+ ++ + PP++P + P+PP G Sbjct: 524 EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRA-PVPPAPPLPGD 582 Query: 1009 AG----PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA------------- 1051 +G PP G + P P P PG + S G TA Sbjct: 583 SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 642 Query: 1052 --GPQQQQPAGAPQPGAVPPG--VPPPGP-HGPSPFPNQQTPPSMMPGAV----PGSGHP 1102 P + G P P ++P G +PPP P G + P PP +PG+ P P Sbjct: 643 PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP---PPPPPLPGSAGIPPPPPPLP 699 Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPD-PGTPLPPDPTAPSPGTVTPVPPP 1151 G A P G +P P P PG P PP PG P PPP Sbjct: 700 GEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP------PGMGMPPPPP 743 Score = 68.2 bits (165), Expect = 4e-11 Identities = 67/254 (26%), Positives = 100/254 (39%), Gaps = 28/254 (11%) Query: 910 VEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQ 969 +++ K++ A E + KKL+ +L EL+ M + E + Q L ++ A H E+ Sbjct: 460 IDKTKVEKSEAKAAELE-KKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEK 518 Query: 970 LKYA-EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAG---PPAVHGLA-VAPASV 1024 + A E + + Q+ + + L + + AA PP+V A V PA Sbjct: 519 QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPP 578 Query: 1025 VPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHG-----P 1079 +P +G+ PP G + + P P P PG V PP P G P Sbjct: 579 LPGDSGTIIPPPPAP-----GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPP 633 Query: 1080 SPFPNQQT--PPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDP 1137 P T PP +P GV SP+ + G +P PLP PP P Sbjct: 634 PPLSGDATIPPPPPLP--------EGVGIPSPSSLPG--GTAIPPPPPLPGSARIPPPPP 683 Query: 1138 TAPSPGTVTPVPPP 1151 P + P PPP Sbjct: 684 PLPGSAGIPPPPPP 697 Score = 53.9 bits (128), Expect = 9e-07 Identities = 54/166 (32%), Positives = 60/166 (36%), Gaps = 25/166 (15%) Query: 992 PPPALPPG----SQPIPPTGAA--GPPAVHGLAVAPASVVPAPAGSGAP-PGSLGPSEQI 1044 PPP LP G S P P G A PP + G A P P P G G P P SL I Sbjct: 608 PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPP-PLPEGVGIPSPSSLPGGTAI 666 Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104 G + P P PG+ PPP G + P PP +PG PG P Sbjct: 667 PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP---PPPPPLPGG-PGIPPPPP 722 Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150 P I P P PG +PP P PV P Sbjct: 723 FPGGPGI-------------PPPPPGMGMPPPPPFGFGVPAAPVLP 755 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 68.9 bits (167), Expect = 3e-11 Identities = 78/290 (26%), Positives = 113/290 (38%), Gaps = 54/290 (18%) Query: 903 KAKHLAAVEERKIKSLVALLVETQ--MKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960 K++ AA E+K+ S + E Q MKK+E FE+ + E++AL ++QQ+ Sbjct: 476 KSEAKAAELEKKLDSELTARHELQVEMKKME---SDFEQKLQDLQGEKDALHSEKQQIAT 532 Query: 961 DRQAFHMEQLKYA--------EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPT----GA 1008 ++Q E + E+ ++ + PP++P + P+PP G Sbjct: 533 EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRA-PVPPAPPLPGD 591 Query: 1009 AG----PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA------------- 1051 +G PP G + P P P PG + S G TA Sbjct: 592 SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 651 Query: 1052 --GPQQQQPAGAPQPGAVPPG--VPPPGP-HGPSPFPNQQTPPSMMPGAV----PGSGHP 1102 P + G P P ++P G +PPP P G + P PP +PG+ P P Sbjct: 652 PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP---PPPPPLPGSAGIPPPPPPLP 708 Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPD-PGTPLPPDPTAPSPGTVTPVPPP 1151 G A P G +P P P PG P PP PG P PPP Sbjct: 709 GEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP------PGMGMPPPPP 752 Score = 68.2 bits (165), Expect = 4e-11 Identities = 67/254 (26%), Positives = 100/254 (39%), Gaps = 28/254 (11%) Query: 910 VEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQ 969 +++ K++ A E + KKL+ +L EL+ M + E + Q L ++ A H E+ Sbjct: 469 IDKTKVEKSEAKAAELE-KKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEK 527 Query: 970 LKYA-EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAG---PPAVHGLA-VAPASV 1024 + A E + + Q+ + + L + + AA PP+V A V PA Sbjct: 528 QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPP 587 Query: 1025 VPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHG-----P 1079 +P +G+ PP G + + P P P PG V PP P G P Sbjct: 588 LPGDSGTIIPPPPAP-----GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPP 642 Query: 1080 SPFPNQQT--PPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDP 1137 P T PP +P GV SP+ + G +P PLP PP P Sbjct: 643 PPLSGDATIPPPPPLP--------EGVGIPSPSSLPG--GTAIPPPPPLPGSARIPPPPP 692 Query: 1138 TAPSPGTVTPVPPP 1151 P + P PPP Sbjct: 693 PLPGSAGIPPPPPP 706 Score = 53.9 bits (128), Expect = 9e-07 Identities = 54/166 (32%), Positives = 60/166 (36%), Gaps = 25/166 (15%) Query: 992 PPPALPPG----SQPIPPTGAA--GPPAVHGLAVAPASVVPAPAGSGAP-PGSLGPSEQI 1044 PPP LP G S P P G A PP + G A P P P G G P P SL I Sbjct: 617 PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPP-PLPEGVGIPSPSSLPGGTAI 675 Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104 G + P P PG+ PPP G + P PP +PG PG P Sbjct: 676 PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP---PPPPPLPGG-PGIPPPPP 731 Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150 P I P P PG +PP P PV P Sbjct: 732 FPGGPGI-------------PPPPPGMGMPPPPPFGFGVPAAPVLP 764 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 68.6 bits (166), Expect = 3e-11 Identities = 56/169 (33%), Positives = 63/169 (37%), Gaps = 24/169 (14%) Query: 992 PPPALPPG-SQPIPPTGAAGPPAVHGLAVAPASVVPAPA------GSGAPPGSLGPSEQI 1044 PPP P G + P PP G GPP G P V+P P G PP L P + Sbjct: 226 PPPPFPAGQTPPRPPLGPPGPPGPPG-PPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPF 284 Query: 1045 GQ---AGSTAGPQQQQPAGAPQPGAVPP--------GVPPPGPHGPSPFPNQQTPPSMMP 1093 GQ GP P P PG PP G PP P GP P PP +P Sbjct: 285 GQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLP 344 Query: 1094 GAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSP 1142 G PG+ P +P + A S P D P P DP P Sbjct: 345 GPPPGAPPP-----APHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPP 388 Score = 65.1 bits (157), Expect = 4e-10 Identities = 55/174 (31%), Positives = 63/174 (36%), Gaps = 31/174 (17%) Query: 993 PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052 P A+P G + P G GPP P P G PPG P + + AG Sbjct: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVL--PPPLAG 265 Query: 1053 PQQQ------------QPAGAPQPGAVPPGVPPPGP-HGPSPFPNQQTPPSMMPGAVPGS 1099 P + QP G P G +PPG PPP P +GP P P PP P PG Sbjct: 266 PPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGP---PPPQQGPPPPPGP 322 Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPV--PPP 1151 P G L P + P P P PP P V P PPP Sbjct: 323 FPP-----------RPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPP 365 Score = 62.0 bits (149), Expect = 3e-09 Identities = 53/150 (35%), Positives = 60/150 (40%), Gaps = 24/150 (16%) Query: 1007 GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA--PQP 1064 G AGPP A P G G PG++ ++ GP PAG P+P Sbjct: 184 GKAGPPGGSSRAAFPQG----GRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP 239 Query: 1065 GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSAS 1124 PPG PPGP GP P P Q PP P +G P + P V L P Sbjct: 240 PLGPPG--PPGPPGPPP-PGQVLPP-------PLAGPPNRGDRPPPPV------LFPGQP 283 Query: 1125 PLPDPGTPLPPDPTAPSPGTVTP--VPPPQ 1152 P PLPP P P PG P PPPQ Sbjct: 284 FGQPPLGPLPPGPPPPVPGYGPPPGPPPPQ 313 Score = 38.9 bits (89), Expect = 0.028 Identities = 36/113 (31%), Positives = 40/113 (35%), Gaps = 25/113 (22%) Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS- 1099 S + Q+G +G + P G A P G G F PGAVPG Sbjct: 171 SRKTTQSGQMSGEGKAGPPGGSSRAAFPQG-----GRGRGRF----------PGAVPGGD 215 Query: 1100 ---GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149 G G P A P PL PG P PP P P PG V P P Sbjct: 216 RFPGPAGPGGPPPPFPA----GQTPPRPPLGPPGPPGPPGP--PPPGQVLPPP 262 >gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens] Length = 828 Score = 68.2 bits (165), Expect = 4e-11 Identities = 55/208 (26%), Positives = 91/208 (43%), Gaps = 37/208 (17%) Query: 324 YTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTKKDSESAPVKGGTMTDLDEQ 383 ++KS RG + E++D T E +TL + D +S +L++Q Sbjct: 272 FSKSSRGCLQNEKQDETLSSSE---------ITLWTEKQSNGDKKSI--------ELNDQ 314 Query: 384 EDESMETTGKDEDENSTGNKGEQTKNPD--------------LHEDNVTEQTHH---III 426 + + D Q +P+ H + E++H + Sbjct: 315 KFNELIKNCNKHDGRGIIVDARQLPSPEPCEIQKNLNDNEMLFHSCQMVEESHEEEELKP 374 Query: 427 PSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTAC 486 P D N + E++A+PEFF G+ ++KTPE YL RN+++D + + +YL T+ Sbjct: 375 PEQEIEIDRNIIQEEEKQAIPEFFEGR-QAKTPERYLKIRNYILDQWEICKPKYLNKTSV 433 Query: 487 RRNL--AGDVCAIMRVHAFLEQWGLINY 512 R L GDV I R+H +LE G IN+ Sbjct: 434 RPGLKNCGDVNCIGRIHTYLELIGAINF 461 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 67.0 bits (162), Expect = 1e-10 Identities = 59/167 (35%), Positives = 74/167 (44%), Gaps = 26/167 (15%) Query: 983 QQMHQQQQQPPPALPP--GSQ-PIPPT-----GAAGPPAVHGLAVAPASVVPAPAGSGAP 1034 Q+M +Q+ PPP P G+Q P PP G +GP L +AP P P G P Sbjct: 305 QEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPP--PTPRGP-PP 361 Query: 1035 PGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGP----HGPSPFPNQQTPPS 1090 PG GP A +GP P GA P PP PPP P +GP+P P PP+ Sbjct: 362 PGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPP---LPPA 418 Query: 1091 MMP--GAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP 1135 ++P G PG G + Q I +Q N P A P+ PP Sbjct: 419 LVPAGGLAPGGGRGALLDQ---IRQGIQLNKTPGA---PESSALQPP 459 Score = 51.6 bits (122), Expect = 4e-06 Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 28/123 (22%) Query: 1034 PPGSLGPSEQ-----IGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTP 1088 PP S G ++ +G +GP P G P P G PPPG GP P P T Sbjct: 317 PPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATG 376 Query: 1089 PS-MMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTP 1147 S +P PG+G P P+P P P PP P++ + P Sbjct: 377 RSGPLPPPPPGAGGP----------------------PMPPPPPPPPPPPSSGNGPAPPP 414 Query: 1148 VPP 1150 +PP Sbjct: 415 LPP 417 Score = 37.0 bits (84), Expect = 0.11 Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 9/81 (11%) Query: 1071 VPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPG 1130 +PPP P PS NQ P ++ G G G P +A P+ P PG Sbjct: 313 LPPPPP--PSRGGNQLPRPPIVGG---NKGRSGPLPPVPLGIAPPP----PTPRGPPPPG 363 Query: 1131 TPLPPDPTAPSPGTVTPVPPP 1151 PP P P+ G P+PPP Sbjct: 364 RGGPPPPPPPATGRSGPLPPP 384 Score = 35.4 bits (80), Expect = 0.31 Identities = 34/90 (37%), Positives = 40/90 (44%), Gaps = 21/90 (23%) Query: 992 PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPA--PAGSGAPPGSLGP-SEQIGQAG 1048 PPP PP P PP+ GP AP + PA PAG AP G G +QI Q Sbjct: 394 PPP--PPPPPP-PPSSGNGP--------APPPLPPALVPAGGLAPGGGRGALLDQIRQ-- 440 Query: 1049 STAGPQQQQPAGAPQPGAVPPGVPPPGPHG 1078 G Q + GAP+ A+ P PP G Sbjct: 441 ---GIQLNKTPGAPESSALQP--PPQSSEG 465 Score = 34.3 bits (77), Expect = 0.70 Identities = 27/83 (32%), Positives = 30/83 (36%), Gaps = 9/83 (10%) Query: 1070 GVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDP 1129 G PP P G +P PP+ PG G P P G L P P Sbjct: 340 GPLPPVPLGIAP-----PPPTPRGPPPPGRGGP---PPPPPPATGRSGPLPPPPPGAGGP 391 Query: 1130 GTPLPPDPTAPSPGTVT-PVPPP 1151 P PP P P P + P PPP Sbjct: 392 PMPPPPPPPPPPPSSGNGPAPPP 414 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 67.0 bits (162), Expect = 1e-10 Identities = 57/168 (33%), Positives = 68/168 (40%), Gaps = 17/168 (10%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAV----APASVVPAPAGSG--APPGSLGPSEQI 1044 Q PP+ PP S P+ P P A + LAV AP S P+P +PP S S Sbjct: 631 QAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP-- 687 Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104 S P Q P+ A P VPP P P PS P Q PP + A P P Sbjct: 688 ----SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL--AAPPLQVPPSP 741 Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152 A P +A +P L P +PP P A P + PPPQ Sbjct: 742 PASPPMSPSATPPPRVPPL--LAAPPLQVPPSPPASLPMSPLAKPPPQ 787 Score = 59.3 bits (142), Expect = 2e-08 Identities = 54/169 (31%), Positives = 65/169 (38%), Gaps = 22/169 (13%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050 Q PP+ PP S P+ P+ P A LA P V P+P S PP S S Sbjct: 705 QVPPS-PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS--PPMS----------PSA 751 Query: 1051 AGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAV-----PGSGHPGVA 1105 P + P A P VPP P P P P Q PP++ + P + PG A Sbjct: 752 TPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQA 811 Query: 1106 AQSPAIVAAVQGNLLPSASPLPDPGTPL---PPDPTAPSPGTVTPVPPP 1151 SP+ + P P PL PP P A SP P PP Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA-SPTLQAPRRPP 859 Score = 57.0 bits (136), Expect = 1e-07 Identities = 52/176 (29%), Positives = 64/176 (36%), Gaps = 23/176 (13%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050 + PP P PP+ PP P+S+ P APP P Q G Sbjct: 559 ETPPCPAPCPLQAPPSPLTTPPPE-----TPSSIATPPPQ--APPALASPPLQ-GLPSPP 610 Query: 1051 AGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAV-------PGSGHPG 1103 P P AP A+PP PP P P TP P A+ P S P Sbjct: 611 LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670 Query: 1104 VAAQSPAIVAAVQGNLLPSASP-------LPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152 Q+P A + PSA+P L P +PP P A P + + PPPQ Sbjct: 671 PPVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725 Score = 53.5 bits (127), Expect = 1e-06 Identities = 56/167 (33%), Positives = 65/167 (38%), Gaps = 24/167 (14%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050 Q PP+ PP S P+ P+ A PP V L AP VP +PP SL P + + Sbjct: 736 QVPPS-PPASPPMSPS-ATPPPRVPPLLAAPPLQVPP-----SPPASL-PMSPLAKPPPQ 787 Query: 1051 AGPQQQQP--AGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPG--AVPGSGHPGVAA 1106 A P P P P A PG P P P TPP P A P P Sbjct: 788 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 847 Query: 1107 QSPAIVAAVQGNLLPSASPLPDPGTPL--PPDPTAPSPGTVTPVPPP 1151 SP + A P P P P T + P A +PG P PPP Sbjct: 848 ASPTLQA-------PRRPPTPGPDTSVSGPRLTLALAPG---PPPPP 884 Score = 51.6 bits (122), Expect = 4e-06 Identities = 54/197 (27%), Positives = 67/197 (34%), Gaps = 38/197 (19%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050 Q PP+ PP S P+ P P A LA P +P+P S PS + + Sbjct: 767 QVPPS-PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825 Query: 1051 AGPQQQQPAGA-------PQPGAVP----PGVPP-PGP----HGP----SPFPNQQTPPS 1090 P Q P A P P A P P PP PGP GP + P PPS Sbjct: 826 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885 Query: 1091 MMPGAVPG----SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGT-------------PL 1133 P + +GH A +P + A+ P P P Sbjct: 886 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA 945 Query: 1134 PPDPTAPSPGTVTPVPP 1150 PP +PG P PP Sbjct: 946 PPLAFRGAPGAPLPWPP 962 Score = 47.0 bits (110), Expect = 1e-04 Identities = 49/164 (29%), Positives = 60/164 (36%), Gaps = 21/164 (12%) Query: 995 ALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP----GSLGPSE-QIGQAGS 1049 +L S P + PP ++AP S+ PA PP SL P Q A Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553 Query: 1050 TAGPQQQQPAGAPQPGAVPPG-VPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQS 1108 T + P AP P PP + P P PS TPP P A+ S Sbjct: 554 TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI---ATPPPQAPPAL----------AS 600 Query: 1109 PAIVAAVQGNLLPSASPLPD--PGTPLPPDPTAPSPGTVTPVPP 1150 P + L P A+P P P LPP PSP P+ P Sbjct: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644 Score = 44.7 bits (104), Expect = 5e-04 Identities = 44/168 (26%), Positives = 61/168 (36%), Gaps = 15/168 (8%) Query: 989 QQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVV-PAPAGSGA--PPGSLGPSEQIG 1045 Q+ +L + P+ +GP A G APA P P G A PP P + Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSA-RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD-- 291 Query: 1046 QAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVA 1105 A GP P P P PP + +P P P + +P +A Sbjct: 292 -AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP------LA 344 Query: 1106 AQSPAIVAAVQGNLLPSASP--LPDPGTPLPPDPTAPSPGTVTPVPPP 1151 SP+ ++Q P A+P P PP PS T+ P+ P Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392 Score = 42.4 bits (98), Expect = 0.003 Identities = 41/165 (24%), Positives = 57/165 (34%), Gaps = 26/165 (15%) Query: 1009 AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS--EQIGQAGSTAGPQQQQPAGAPQPGA 1066 AG A A AP + P P GS PP + P+ +G AG+ + AG Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69 Query: 1067 VPPGVPPPGP--------HGPS-------------PFPNQQTPPSMMPGAVPGSGHPGVA 1105 +P P GP P+ P N P PG G+ PG Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129 Query: 1106 AQSPAIVAAVQGNLLPSASPLPDP---GTPLPPDPTAPSPGTVTP 1147 Q ++A + A+ P D + P+PGT +P Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174 Score = 40.4 bits (93), Expect = 0.010 Identities = 44/170 (25%), Positives = 61/170 (35%), Gaps = 22/170 (12%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050 +P P + P+P T PP L +AP P S PS Q + Sbjct: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLAP------------PSPSAPPSLQTLPSPPA 362 Query: 1051 AGPQQQQPAGAPQPGAVPPG---VPP-PGPHGPSPFPNQQTPPSMMP----GAVPGSGHP 1102 P Q P+ P PP +PP PH + P+ Q PPS + A G P Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS-PSLQAPPSPLALSSLQATTSLGSP 421 Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152 + A + + + SP TP P P +P ++ PP Q Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQAPLSLPASPPLQ 470 Score = 34.7 bits (78), Expect = 0.54 Identities = 42/167 (25%), Positives = 58/167 (34%), Gaps = 38/167 (22%) Query: 994 PALPPGSQPIPPTGAAGPPAVHGLAV--------APASVVPAPAGSGAPPGSLGPSEQIG 1045 P PP P P T +GP LA +P+S + P +G + E++ Sbjct: 855 PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912 Query: 1046 ------QAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS 1099 + G+ A P A P A G PP +P PP+ PG+ G Sbjct: 913 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972 Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP--DPTAPSPGT 1144 + +G P+ TP P DP PSPGT Sbjct: 973 ----------CTIYETEG---------PESATPAPGALDP-GPSPGT 999 >gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens] Length = 2524 Score = 65.9 bits (159), Expect = 2e-10 Identities = 76/367 (20%), Positives = 138/367 (37%), Gaps = 28/367 (7%) Query: 786 GNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSD 845 G + + + Q ++++ ++P E++ KEK EA K++E+ E D E ++ Sbjct: 491 GKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKT 550 Query: 846 GDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVKAK 905 D + EKE + ++ S+G RK ++ R +++ A + A ++ Sbjct: 551 DDTSGEDNDEKEAVASKG---RKTANSQGRRKGRITR-----SMANEANSEEAITPQQSA 602 Query: 906 HLAAVEERKIKSLVALLVETQMKKLEIKLRHFEEL------ETIMDREREALEYQRQQLL 959 LA++E + +ET K L R++ + +T+ + Y+++Q L Sbjct: 603 ELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNL 662 Query: 960 AD-RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLA 1018 + Q ++ K R +++ ++ PP + V Sbjct: 663 DEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAE 722 Query: 1019 VAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-----PP 1073 AS P G + P ++ S S P + Q G PP PP Sbjct: 723 ALHASGNEVPRGECSGPATVNNS---SDTESIPSPHTEAAKDTGQNGPKPPATLGADGPP 779 Query: 1074 PGPHGPS----PFPNQQTPPSMMPGA-VPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPD 1128 PGP P P P + TP S GA P P +A P + + +A P+ + Sbjct: 780 PGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEE 839 Query: 1129 PGTPLPP 1135 PP Sbjct: 840 GEEQKPP 846 Score = 57.8 bits (138), Expect = 6e-08 Identities = 130/652 (19%), Positives = 218/652 (33%), Gaps = 92/652 (14%) Query: 545 QPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPEL----------------QTSASQQ 588 Q P+ Q + D K K E ++ PE K +L + AS+ Sbjct: 509 QQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKG 568 Query: 589 MLNFPDKGKEK---PTDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALE 645 +G+ K M N + T + + + + WTE+E + L Sbjct: 569 RKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGLL 628 Query: 646 MYKDDWNKVSEHVGSRTQDEC---ILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGN 702 + +W+ ++ VGS+T +C ++ + D L+ + + ++ Sbjct: 629 EHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPA 688 Query: 703 PVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKAD- 761 AF V D + ++ EE + E + + E + A V +D Sbjct: 689 AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDT 748 Query: 762 ---PAFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEKKEPKEP---REGGGAIEE 815 P+ E++ G +P + ++ P EP E GA Sbjct: 749 ESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTP 808 Query: 816 EAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGE 875 + AP K EKE E + P+ + E++K P EE+ + ++E Sbjct: 809 PPAPPSPSAPPPVVPK-----EEKEEETAAAPPVEEGEEQKPP--AAEELAVDTGKAEEP 861 Query: 876 RKTKVERDIGEG---NLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEI 932 K++ + EG AA A A A+KA+ R + + + Sbjct: 862 VKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATC 921 Query: 933 KLRHFEELETIMDREREALEYQRQQLLAD-----RQAFHMEQLKYAEMRARQQHFQQMHQ 987 +E E ++ L R LL A + L +++ R + Sbjct: 922 SADEVDEAE---GGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVT 978 Query: 988 QQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047 + +PP ++P PP A PP + + P S P GS S P+ Sbjct: 979 KVHEPPREDAAPTKPAPP---APPPPQN---LQPESDAPQQPGSSPRGKSRSPA------ 1026 Query: 1048 GSTAGPQQQQPAGAPQPGAVP---PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104 A + ++P P A PG PP G PFP PP + A P + P Sbjct: 1027 -PPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSG-LPFP---VPPREVIKASPHAPDPSA 1081 Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLP------PDPTAPSPGTVTPVPP 1150 + +P PG PLP P P P T++ PP Sbjct: 1082 FSYAP-------------------PGHPLPLGLHDTARPVLPRPPTISNPPP 1114 Score = 31.6 bits (70), Expect = 4.5 Identities = 26/102 (25%), Positives = 37/102 (36%), Gaps = 3/102 (2%) Query: 305 PSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTK 364 PSP EA K + GP P T G +D+ P+ E T T Sbjct: 752 PSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPA 811 Query: 365 KDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQ 406 S SAP + +E+E+E+ +E E E+ Sbjct: 812 PPSPSAP---PPVVPKEEKEEETAAAPPVEEGEEQKPPAAEE 850 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 65.9 bits (159), Expect = 2e-10 Identities = 90/368 (24%), Positives = 136/368 (36%), Gaps = 46/368 (12%) Query: 820 KTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTK 879 K + P K+E ES S+ P+ P +E P EE E E + K + Sbjct: 324 KDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLK-Q 382 Query: 880 VERDIGEGNLSTAAAAALAAAAVKAKHLAAVEE-RKIKSLVALLVETQMKKLEIKLRHFE 938 ++ + KH + ++ + ++ Q ++++LRH+E Sbjct: 383 LQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYE 442 Query: 939 ELETIMDREREALEYQRQQLLADRQAF---HMEQLKYAE---------MRARQQH----- 981 + + E++R+ L + Q H +QL+ E M+A Q + Sbjct: 443 MQQQQFQHLYQ--EWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKV 500 Query: 982 --FQQMHQQ----QQQPPPALPPGSQPIP-PTGAAG--PPAVHGLAVAPA--SVVPAPAG 1030 FQ M Q PPP +P P P PT PP++ + PA + VP P Sbjct: 501 NSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPP-- 558 Query: 1031 SGAPPGSLGPS--EQIGQAG-----STAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFP 1083 G PP + PS + G S+AGP P + PP +PPP +P P Sbjct: 559 -GMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPP 617 Query: 1084 NQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPT-APSP 1142 PP PG PGV P + A +P AS P P P P+P Sbjct: 618 VMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAP---VPPASSSQSSQVPEKPRPALLPTP 674 Query: 1143 GTVTPVPP 1150 + PP Sbjct: 675 VSFGSAPP 682 Score = 47.4 bits (111), Expect = 8e-05 Identities = 63/217 (29%), Positives = 81/217 (37%), Gaps = 60/217 (27%) Query: 977 ARQQHFQQMHQQQQQ---------PPPALPP--------GSQPIPPTGAAGPPA------ 1013 A+ Q QQMHQ+Q Q PPP PP G PP PP Sbjct: 59 AQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQ 118 Query: 1014 ---------VHGLAVAPASVVP-----APAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPA 1059 +H P +VP P PPGS P Q S P Q P+ Sbjct: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQ-----SYMPPPQPPPS 173 Query: 1060 GAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNL 1119 P P + P +PP PSP Q+PPS A P + ++ S + ++ Q + Sbjct: 174 YYP-PTSSQPYLPPA---QPSP---SQSPPSQSYLA-PTPSYSSSSSSSQSYLSHSQ-SY 224 Query: 1120 LPSASPLPDPGTP--------LPPDPTAPSPGTVTPV 1148 LPS+ P + PP P+AP PG T V Sbjct: 225 LPSSQASPSRPSQGHSKSQLLAPPPPSAP-PGNKTTV 260 Score = 45.8 bits (107), Expect = 2e-04 Identities = 51/183 (27%), Positives = 66/183 (36%), Gaps = 25/183 (13%) Query: 978 RQQHFQQMHQQQQQPPPAL-------PPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAG 1030 +QQ+ QM Q+ PP L PP S P+PP G+ PP+ + P P Sbjct: 120 QQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPP-GSYMPPSQSYMP------PPQPPP 172 Query: 1031 SGAPPGSLGPSEQIGQ-AGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP 1089 S PP S P Q + S + P Q A P + H S P+ Q P Sbjct: 173 SYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASP 232 Query: 1090 SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLL-----PSASPLPDPGTPLPPDPTAPSPGT 1144 S P GH +P +A GN P S + T P P T Sbjct: 233 SR-----PSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPST 287 Query: 1145 VTP 1147 +TP Sbjct: 288 MTP 290 Score = 43.5 bits (101), Expect = 0.001 Identities = 47/173 (27%), Positives = 63/173 (36%), Gaps = 28/173 (16%) Query: 992 PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051 PPP +PP P A P A G + ++ AP+ SG Q+ Q Sbjct: 15 PPPPVPP------PPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68 Query: 1052 GPQQQ---QPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV---- 1104 Q Q QP P P PP V P G +G Q PP M P P + Sbjct: 69 QKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDW----QPPPPPMPPPPGPALSYQKQQQYK 124 Query: 1105 ------AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPP 1151 P + ++ P + P+P PG+ +PP + P P PPP Sbjct: 125 HQMLHHQRDGPPGLVPMELESPPESPPVP-PGSYMPPSQSYMPP----PQPPP 172 Score = 39.7 bits (91), Expect = 0.017 Identities = 39/141 (27%), Positives = 53/141 (37%), Gaps = 28/141 (19%) Query: 1030 GSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPP-GVPPPGPHGPSPFPNQQTP 1088 G PPGS P +G+ + PA + P PP +PPP P P P P P Sbjct: 1504 GMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPP----P 1559 Query: 1089 PSMMP----------------GAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTP 1132 P + P G + G+ ++ + AA+ PSA LP P Sbjct: 1560 PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAI-----PSAPVLPPPPVH 1614 Query: 1133 LPPDPTAPSPGTVTPV--PPP 1151 P P P + P+ PPP Sbjct: 1615 SSIPPPGPVPMGMPPMSKPPP 1635 Score = 38.9 bits (89), Expect = 0.028 Identities = 50/211 (23%), Positives = 72/211 (34%), Gaps = 50/211 (23%) Query: 984 QMHQQQQQPPPAL-PPGSQ-----PIPPTGAAGPPAVHGLAVAPA--------------- 1022 Q + QPPP+ PP S P P+ + PP+ LA P+ Sbjct: 162 QSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHS 221 Query: 1023 --------------------SVVPAPAGSGAPPGSLGPSEQ--IGQAGSTAGPQQQQPAG 1060 S + AP APPG+ +Q + +QQQ A Sbjct: 222 QSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAP 281 Query: 1061 APQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLL 1120 P P + P + QQ +PG G P VA +P V + + Sbjct: 282 EPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKG---PVVAKDTPEPVK--EEVTV 336 Query: 1121 PSASPLPDPGTPLPPDPTAPSPGTVTPVPPP 1151 P+ S +P+ +P +P P P P P P Sbjct: 337 PATSQVPE--SPSSEEPPLPPPNEEVPPPLP 365 Score = 36.2 bits (82), Expect = 0.18 Identities = 51/232 (21%), Positives = 84/232 (36%), Gaps = 42/232 (18%) Query: 931 EIKLRHFEELETIMDREREALEYQRQQLLADRQAFHM--EQLKYAEMRARQQHFQQMHQQ 988 EI L+ +EL+ + + ++E L+ + + A H+ ++ + +R + Sbjct: 1454 EIILKAAQELKMLRE-QKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSY 1512 Query: 989 QQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAG 1048 + PP PPGS P + PPA + P + P P PP L P + + Sbjct: 1513 RPPPPMGKPPGSIVRP----SAPPARSSV---PVTRPPVPIPPPPPPPPLPPPPPVIKPQ 1565 Query: 1049 STAGPQQQ------------------------QPAGAPQPGAVPP-----GVPPPGPHGP 1079 ++A Q++ + A P +PP +PPPGP P Sbjct: 1566 TSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGP-VP 1624 Query: 1080 SPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGT 1131 P PP + G G + I + L P PLP+ T Sbjct: 1625 MGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRP--DPLPERST 1674 Score = 32.7 bits (73), Expect = 2.0 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 29/84 (34%) Query: 1069 PGV-PPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLP 1127 PG+ PPPG + P P P PG++ P PA S+ P+ Sbjct: 1503 PGMYPPPGSYRPPP------PMGKPPGSIVRPSAP------PA----------RSSVPVT 1540 Query: 1128 DPGTPLPPDPTAPSPGTVTPVPPP 1151 P P+PP P P P+PPP Sbjct: 1541 RPPVPIPPPPPPP------PLPPP 1558 Score = 32.3 bits (72), Expect = 2.7 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 9/80 (11%) Query: 1079 PSPF-PNQQTPP---SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLP 1134 P PF P Q PP +M P +P S P V PA+ A V +P P T +P Sbjct: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPV--MPPALPATVPPPGMPPPVMPPSLPTSVP 574 Query: 1135 PDPTAPSPGTVTP---VPPP 1151 P PS + P +PPP Sbjct: 575 PPGMPPSLSSAGPPPVLPPP 594 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 65.1 bits (157), Expect = 4e-10 Identities = 59/168 (35%), Positives = 69/168 (41%), Gaps = 18/168 (10%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAV----APASVVPAPAGSG--APPGSLGPSEQI 1044 Q PP+ PP S P+ P P A + LAV AP S P+P +PP S S Sbjct: 406 QAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP-- 462 Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104 S P Q P+ A P VPP P P PS P Q PP P A P Sbjct: 463 ----SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---PLAAPPLQLAKP 515 Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152 Q+P +A LPS P PG P P+A P + PPPQ Sbjct: 516 PPQAPPALATPPLQALPS-PPASFPG-QAPFSPSASLPMSPLATPPPQ 561 Score = 55.5 bits (132), Expect = 3e-07 Identities = 57/188 (30%), Positives = 70/188 (37%), Gaps = 25/188 (13%) Query: 989 QQQPPPALP--PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPG----SLG-PS 1041 Q Q PP LP P S + A P AP S+ P+ PP SLG P+ Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 373 Query: 1042 EQIGQA---GSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAV-- 1096 Q + P P AP A+PP PP P P TP P A+ Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433 Query: 1097 -----PGSGHPGVAAQSPAIVAAVQGNLLPSASP-------LPDPGTPLPPDPTAPSPGT 1144 P S P Q+P A + PSA+P L P +PP P A P + Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492 Query: 1145 VTPVPPPQ 1152 + PPPQ Sbjct: 493 PSATPPPQ 500 Score = 51.6 bits (122), Expect = 4e-06 Identities = 53/179 (29%), Positives = 65/179 (36%), Gaps = 37/179 (20%) Query: 994 PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSG-----------APPGSLGPSE 1042 P PP S P+ P+ A LA P V P+P S APP P Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510 Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP 1102 Q+ + P Q PA A P P P P G +PF + P M P A P Sbjct: 511 QLAKP-----PPQAPPALATPPLQALPSPPASFP-GQAPFSPSASLP-MSPLATP----- 558 Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGT----------VTPVPPP 1151 Q+P ++AA + P SP P P P P P T + P PPP Sbjct: 559 --PPQAPPVLAAPLLQVPP--SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613 Score = 48.5 bits (114), Expect = 4e-05 Identities = 61/221 (27%), Positives = 74/221 (33%), Gaps = 60/221 (27%) Query: 988 QQQQPPPALPPG-------SQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040 Q +PPP PP + P PP G A P S + P APP P Sbjct: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ-APPVLAAP 569 Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPG------------AVPPGVPPPGPHGPSP------F 1082 Q+ + A P Q P P PG A+ PG PPP PS Sbjct: 570 LLQVPPS-PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 628 Query: 1083 PNQQTPPSMMPGAVPG--SGHPGVAAQSP---AIVAAVQGNLLPSASPLPD------PGT 1131 + + P + G SG G AA SP A +AA S P P PG Sbjct: 629 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW-SRGPAPPLAFRGAPGA 687 Query: 1132 PLP---------------------PDPTAPSPGTVTPVPPP 1151 PLP P+ P+PG + P P P Sbjct: 688 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728 Score = 47.8 bits (112), Expect = 6e-05 Identities = 56/199 (28%), Positives = 67/199 (33%), Gaps = 42/199 (21%) Query: 989 QQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAG 1048 Q PP A PP PP A PPA LA P +P+P S PS + + Sbjct: 500 QAPPPLAAPPLQLAKPPPQA--PPA---LATPPLQALPSPPASFPGQAPFSPSASLPMSP 554 Query: 1049 STAGPQQQQPAGA-------PQPGAVP----PGVPP-PGP----HGP----SPFPNQQTP 1088 P Q P A P P A P P PP PGP GP + P P Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614 Query: 1089 PSMMPGAVPG----SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGT------------- 1131 PS P + +GH A +P + A+ P P Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674 Query: 1132 PLPPDPTAPSPGTVTPVPP 1150 P PP +PG P PP Sbjct: 675 PAPPLAFRGAPGAPLPWPP 693 Score = 43.1 bits (100), Expect = 0.002 Identities = 49/163 (30%), Positives = 61/163 (37%), Gaps = 23/163 (14%) Query: 1005 PTGAAGP--PAVHGL-AVAPASVVPAPAGSGAPPGSLGP--SEQIGQAGSTAGPQQQQPA 1059 P A P P GL A+ P V P P AP +LGP S + +A Q Q P Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTP-PRKDAAP--ALGPLSSSPLATPSPSAALQSQAPP 319 Query: 1060 GAPQPG---------AVPPGVPPPGPHGPSPFPNQQTPPSMMPG-AVPGSGHPGVAAQSP 1109 P A P + PP P P +PP+ P A G P + A Sbjct: 320 TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 379 Query: 1110 AIVAAVQGNLLPSASPLPD--PGTPLPPDPTAPSPGTVTPVPP 1150 + + L P A+P P P LPP PSP P+ P Sbjct: 380 FLPSP---PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 419 Score = 42.4 bits (98), Expect = 0.003 Identities = 41/165 (24%), Positives = 57/165 (34%), Gaps = 26/165 (15%) Query: 1009 AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS--EQIGQAGSTAGPQQQQPAGAPQPGA 1066 AG A A AP + P P GS PP + P+ +G AG+ + AG Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69 Query: 1067 VPPGVPPPGP--------HGPS-------------PFPNQQTPPSMMPGAVPGSGHPGVA 1105 +P P GP P+ P N P PG G+ PG Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129 Query: 1106 AQSPAIVAAVQGNLLPSASPLPDP---GTPLPPDPTAPSPGTVTP 1147 Q ++A + A+ P D + P+PGT +P Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174 Score = 34.7 bits (78), Expect = 0.54 Identities = 42/167 (25%), Positives = 58/167 (34%), Gaps = 38/167 (22%) Query: 994 PALPPGSQPIPPTGAAGPPAVHGLAV--------APASVVPAPAGSGAPPGSLGPSEQIG 1045 P PP P P T +GP LA +P+S + P +G + E++ Sbjct: 586 PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643 Query: 1046 ------QAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS 1099 + G+ A P A P A G PP +P PP+ PG+ G Sbjct: 644 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 703 Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP--DPTAPSPGT 1144 + +G P+ TP P DP PSPGT Sbjct: 704 ----------CTIYETEG---------PESATPAPGALDP-GPSPGT 730 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 65.1 bits (157), Expect = 4e-10 Identities = 59/168 (35%), Positives = 69/168 (41%), Gaps = 18/168 (10%) Query: 991 QPPPALPPGSQPIPPTGAAGPPAVHGLAV----APASVVPAPAGSG--APPGSLGPSEQI 1044 Q PP+ PP S P+ P P A + LAV AP S P+P +PP S S Sbjct: 367 QAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP-- 423 Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104 S P Q P+ A P VPP P P PS P Q PP P A P Sbjct: 424 ----SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---PLAAPPLQLAKP 476 Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152 Q+P +A LPS P PG P P+A P + PPPQ Sbjct: 477 PPQAPPALATPPLQALPS-PPASFPG-QAPFSPSASLPMSPLATPPPQ 522 Score = 55.8 bits (133), Expect = 2e-07 Identities = 55/197 (27%), Positives = 70/197 (35%), Gaps = 36/197 (18%) Query: 988 QQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGA-----PPGSLGPSE 1042 Q +PP PP P A GP + LA S P+P+ + P + PS+ Sbjct: 269 QALRPPQVTPPRKDAAP---ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325 Query: 1043 QIGQAGSTA-------------GPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP 1089 GS P P AP A+PP PP P P TP Sbjct: 326 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385 Query: 1090 SMMPGAV-------PGSGHPGVAAQSPAIVAAVQGNLLPSASP-------LPDPGTPLPP 1135 P A+ P S P Q+P A + PSA+P L P +PP Sbjct: 386 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVPP 444 Query: 1136 DPTAPSPGTVTPVPPPQ 1152 P A P + + PPPQ Sbjct: 445 SPPASPPMSPSATPPPQ 461 Score = 51.6 bits (122), Expect = 4e-06 Identities = 53/179 (29%), Positives = 65/179 (36%), Gaps = 37/179 (20%) Query: 994 PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSG-----------APPGSLGPSE 1042 P PP S P+ P+ A LA P V P+P S APP P Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 471 Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP 1102 Q+ + P Q PA A P P P P G +PF + P M P A P Sbjct: 472 QLAKP-----PPQAPPALATPPLQALPSPPASFP-GQAPFSPSASLP-MSPLATP----- 519 Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGT----------VTPVPPP 1151 Q+P ++AA + P SP P P P P P T + P PPP Sbjct: 520 --PPQAPPVLAAPLLQVPP--SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574 Score = 48.5 bits (114), Expect = 4e-05 Identities = 61/221 (27%), Positives = 73/221 (33%), Gaps = 60/221 (27%) Query: 988 QQQQPPPALPPG-------SQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040 Q +PPP PP + P PP G A P S + P APP P Sbjct: 472 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ-APPVLAAP 530 Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPG------------AVPPGVPPPGPHGPS------PF 1082 Q+ A P Q P P PG A+ PG PPP PS Sbjct: 531 LLQV-PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 589 Query: 1083 PNQQTPPSMMPGAVPG--SGHPGVAAQSP---AIVAAVQGNLLPSASPLPD------PGT 1131 + + P + G SG G AA SP A +AA S P P PG Sbjct: 590 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW-SRGPAPPLAFRGAPGA 648 Query: 1132 PLP---------------------PDPTAPSPGTVTPVPPP 1151 PLP P+ P+PG + P P P Sbjct: 649 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689 Score = 47.8 bits (112), Expect = 6e-05 Identities = 56/199 (28%), Positives = 67/199 (33%), Gaps = 42/199 (21%) Query: 989 QQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAG 1048 Q PP A PP PP A PPA LA P +P+P S PS + + Sbjct: 461 QAPPPLAAPPLQLAKPPPQA--PPA---LATPPLQALPSPPASFPGQAPFSPSASLPMSP 515 Query: 1049 STAGPQQQQPAGA-------PQPGAVP----PGVPP-PGP----HGP----SPFPNQQTP 1088 P Q P A P P A P P PP PGP GP + P P Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575 Query: 1089 PSMMPGAVPG----SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGT------------- 1131 PS P + +GH A +P + A+ P P Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635 Query: 1132 PLPPDPTAPSPGTVTPVPP 1150 P PP +PG P PP Sbjct: 636 PAPPLAFRGAPGAPLPWPP 654 Score = 46.6 bits (109), Expect = 1e-04 Identities = 41/156 (26%), Positives = 56/156 (35%), Gaps = 17/156 (10%) Query: 1009 AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS--EQIGQAGSTAGPQQQQPAGAPQPGA 1066 AG A A AP + P P GS PP + P+ +G AG+ + AG Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69 Query: 1067 VPPGVPPPGPHGPS------------PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAA 1114 +P P GP S P N P PG G+ PG Q ++A Sbjct: 70 IPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129 Query: 1115 VQGNLLPSASPLPDP---GTPLPPDPTAPSPGTVTP 1147 + A+ P D + P+PGT +P Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 165 Score = 43.5 bits (101), Expect = 0.001 Identities = 47/165 (28%), Positives = 62/165 (37%), Gaps = 32/165 (19%) Query: 992 PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051 P PA P ++P PPT GP A ++ P+PA P +A Sbjct: 181 PRPA--PSARPRPPT--EGPRKSVSSASEHSTTEPSPAARRRP---------------SA 221 Query: 1052 GPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP-GVAAQSPA 1110 G Q+PA + P + P GPS + P A P P G+ A P Sbjct: 222 GGGLQRPASRSLSSSATP-LSSPARSGPSARGTPRAP------AHPSQPKPKGLQALRPP 274 Query: 1111 IVAAVQGNLLP-----SASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150 V + + P S+SPL P PP P+AP P PP Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPP 319 Score = 34.7 bits (78), Expect = 0.54 Identities = 42/167 (25%), Positives = 58/167 (34%), Gaps = 38/167 (22%) Query: 994 PALPPGSQPIPPTGAAGPPAVHGLAV--------APASVVPAPAGSGAPPGSLGPSEQIG 1045 P PP P P T +GP LA +P+S + P +G + E++ Sbjct: 547 PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 604 Query: 1046 ------QAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS 1099 + G+ A P A P A G PP +P PP+ PG+ G Sbjct: 605 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 664 Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP--DPTAPSPGT 1144 + +G P+ TP P DP PSPGT Sbjct: 665 ----------CTIYETEG---------PESATPAPGALDP-GPSPGT 691 >gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] Length = 1488 Score = 65.1 bits (157), Expect = 4e-10 Identities = 59/197 (29%), Positives = 74/197 (37%), Gaps = 38/197 (19%) Query: 979 QQHFQQMHQQQQQ-----PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGA 1033 Q Q +H Q Q PPP LPP +PP PP S+ P PA A Sbjct: 1261 QSKLQALHAQYCQGPGPAPPPYLPPQQPSLPPPPQQPPPLPQ-----LGSIPPPPA--SA 1313 Query: 1034 PPGSLGPSEQIGQAGSTAGPQQQ---QPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPS 1090 PP +GP G GPQ +P AP+ GA G P PHG P P S Sbjct: 1314 PP--VGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGA--GGHPQFAPHGRHPL---HQPTS 1366 Query: 1091 MMPGAVPGSGHPGVAAQSPA-IVAAVQGNLLPSASPLPDPG---------------TPLP 1134 +P P HP Q P + + ++P+A PG +PL Sbjct: 1367 PLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLS 1426 Query: 1135 PDPTAPSPGTVTPVPPP 1151 P P + P+PPP Sbjct: 1427 PHSPIPPHPSYPPLPPP 1443 Score = 45.1 bits (105), Expect = 4e-04 Identities = 40/129 (31%), Positives = 51/129 (39%), Gaps = 18/129 (13%) Query: 981 HFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040 H + Q P P P Q PP GP H + ++PA AG+ PGS P Sbjct: 1356 HGRHPLHQPTSPLPLYSPAPQH-PPAHKQGPK--HFIFSHHPQMMPA-AGAAGGPGSRPP 1411 Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVP----PGVPPPGPHGPSPFPNQQTPPSMMPGAV 1096 GS + P Q +P P P +PPP PH P + PP+ G + Sbjct: 1412 G------GSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTP----HSPLPPTSPHGPL 1461 Query: 1097 PGSGHPGVA 1105 SG PG A Sbjct: 1462 HASGPPGTA 1470 >gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo sapiens] Length = 406 Score = 65.1 bits (157), Expect = 4e-10 Identities = 91/379 (24%), Positives = 135/379 (35%), Gaps = 49/379 (12%) Query: 795 QATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEK 854 + DEK GG EE + K + + G EG + + +G +PE+ Sbjct: 25 EVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQ 84 Query: 855 EKE------PKEGQEE--VLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVKAKH 906 ++E P++ QEE +L+ E E +T VE TA K + Sbjct: 85 QQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGP--QPPERKRRR 142 Query: 907 LAAVEERKIKSLVALLVETQ------MKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960 A + +++ L E+Q ++L +L E+ + + R A + Q++L Sbjct: 143 RTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLM 202 Query: 961 DRQAFHMEQLKYAEMRARQQHFQQ--------MHQQQQQP-PPALPPGSQPIPPTGAAGP 1011 R + +M ++ +H Q P PP LP P P P Sbjct: 203 LRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMP 262 Query: 1012 PAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV 1071 P + P + P P GS P GP P P AP P P Sbjct: 263 PRPPIAPMPP--MAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAP 320 Query: 1072 PPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGT 1131 PPGP P + PP VP P +A P P +PLP PG Sbjct: 321 VPPGP------PMARVPPGPPMARVPPG--PPMAPLPPG----------PPMAPLP-PGP 361 Query: 1132 PLPPDPTAPSPGTVTPVPP 1150 P+ P P P + P+PP Sbjct: 362 PMAPLPPGP---PMAPLPP 377 >gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] Length = 753 Score = 65.1 bits (157), Expect = 4e-10 Identities = 60/180 (33%), Positives = 70/180 (38%), Gaps = 46/180 (25%) Query: 998 PGSQPIPPTGAAGPP-AVHGLAVAPASV-VPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQ 1055 P S +PPT +GPP A L+ P + VPAPA APP +LGP A P Sbjct: 314 PQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPA---APPSALGPK---------ASPAP 361 Query: 1056 QQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPG------------ 1103 +G P P A V PP P GPS Q PPS+ P G G G Sbjct: 362 SHNSGTPAPYA--QAVAPPAPSGPS--TTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAG 417 Query: 1104 --------------VAAQSPAIVA--AVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTP 1147 V A SPA VA + GN S + P G PP T+ P P Sbjct: 418 GGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAP 477 Score = 51.2 bits (121), Expect = 6e-06 Identities = 50/191 (26%), Positives = 70/191 (36%), Gaps = 45/191 (23%) Query: 992 PPPALPPGSQPIPPTGAAGPPAVHGLAVAPA-------------SVVPAPAGSGAPPGSL 1038 PP AL P + P P + G PA + AVAP SV P+ G G G Sbjct: 349 PPSALGPKASPAPSHNS-GTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGG 407 Query: 1039 GPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV----------------PPPGPHGPSPF 1082 S AG AG Q + + P V PP GPH P P Sbjct: 408 SSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPS 467 Query: 1083 PNQQ---TPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTA 1139 +++ P+ G PGSG+ + P+++ + P+ P +P P A Sbjct: 468 TSKEPSAAAPTGAGGVAPGSGN---NSGGPSLLVPL---------PVNPPSSPTPSFSDA 515 Query: 1140 PSPGTVTPVPP 1150 + G + PP Sbjct: 516 KAAGALLNGPP 526 Score = 42.7 bits (99), Expect = 0.002 Identities = 58/220 (26%), Positives = 78/220 (35%), Gaps = 40/220 (18%) Query: 938 EELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALP 997 +++E +D ++ + + L D + Q A H + Q P Sbjct: 205 DDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTST 264 Query: 998 PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQ 1057 S PIPP+ PA+ + G SE + Q+ + G + Sbjct: 265 TSSSPIPPS--------------PANCTTENSEDDKKRGRSTDSE-VSQSPAKNGSKPVH 309 Query: 1058 PAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQG 1117 PQ P VPP P GP P + S PG +G P AA A Sbjct: 310 SNQHPQS----PAVPPTYPSGPPPAASAL---STTPG---NNGVPAPAAPPSA------- 352 Query: 1118 NLLPSASPLP--DPGTPLP----PDPTAPS-PGTVTPVPP 1150 L P ASP P + GTP P P APS P T P PP Sbjct: 353 -LGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPP 391 >gi|148536848 carboxyl ester lipase precursor [Homo sapiens] Length = 756 Score = 64.3 bits (155), Expect = 6e-10 Identities = 57/169 (33%), Positives = 68/169 (40%), Gaps = 24/169 (14%) Query: 993 PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP----GSLG--PSEQIGQ 1046 PP G+ P+PPTG +G P V + A VP SGAPP G G P G Sbjct: 586 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 645 Query: 1047 AGSTAGPQQQQPAGAPQP---GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGA--VPGSGH 1101 +G+ P P P + P VPP G GP P PP+ GA VP +G Sbjct: 646 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPP-----VPPTGDSGAPPVPPTGD 700 Query: 1102 PGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150 G +P + P P D G P P PT S PVPP Sbjct: 701 SG----APPVTPTGDSETAP-VPPTGDSGAP-PVPPTGDS--EAAPVPP 741 Score = 62.0 bits (149), Expect = 3e-09 Identities = 54/160 (33%), Positives = 65/160 (40%), Gaps = 17/160 (10%) Query: 993 PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052 PP + P+PPTG +G P V + A VP SGAPP + P+ G +G+ Sbjct: 575 PPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPP--VPPT---GDSGAPPV 629 Query: 1053 PQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGA--VPGSGHPGVAAQSPA 1110 P P P G PP P G S P PP+ GA VP +G G P Sbjct: 630 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAP--PVPPTGDSGAPPVPPTGDAG-----PP 682 Query: 1111 IVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150 V + P P D G P P PT S PVPP Sbjct: 683 PVPPTGDSGAPPVPPTGDSGAP-PVTPTGDS--ETAPVPP 719 Score = 50.1 bits (118), Expect = 1e-05 Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 14/105 (13%) Query: 993 PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052 PP G+ P+PPTG AGPP V + A VP SGAPP + G Sbjct: 663 PPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPP------------VTPTG 710 Query: 1053 PQQQQPAGAPQPGAVPPGVPPPGPHGPSPF-PNQQTPPSMMPGAV 1096 + P PP VPP G +P P + + MP + Sbjct: 711 DSETAPVPPTGDSGAPP-VPPTGDSEAAPVPPTDDSKEAQMPAVI 754 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 64.3 bits (155), Expect = 6e-10 Identities = 67/250 (26%), Positives = 97/250 (38%), Gaps = 25/250 (10%) Query: 923 VETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHF 982 V Q ++L+ + + + L + + ++ ++ Q+QQL Q QL+ + + +QQ Sbjct: 203 VVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL----QRIAQLQLQQQQQQQQQQQQ 258 Query: 983 QQMHQQQQQPPPALPPGSQPIPPTGAAGPPAV----HGLAVAPASVVPAPAGSGAPPGSL 1038 QQ Q QPP PP QP PP A P + H P P + P L Sbjct: 259 QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQL 318 Query: 1039 GPSEQ----IGQAGSTAGPQ-QQQP----AGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP 1089 P Q + QA + G QP AP PP V P + Q Sbjct: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPP-VQPQVQQQQTAVQTAQAAQ 377 Query: 1090 SMMPGA-VPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPT------APSP 1142 + PG V S P +++ SP ++ P P P PG P + APSP Sbjct: 378 MVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSP 437 Query: 1143 GTVTPVPPPQ 1152 + P P PQ Sbjct: 438 SSFLPSPSPQ 447 Score = 56.2 bits (134), Expect = 2e-07 Identities = 78/290 (26%), Positives = 111/290 (38%), Gaps = 47/290 (16%) Query: 900 AAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLL 959 +A++ + A V++++ L + Q ++ IKL H + + I ++++ + QL Sbjct: 194 SAMQQQFQAVVQQQQ-----QLQQQQQQQQHLIKLHH-QNQQQIQQQQQQLQRIAQLQLQ 247 Query: 960 ADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPP--ALPPGSQPI-------PPTGAAG 1010 +Q +Q + + Q QQ QQ QPPP ALP Q + PP Sbjct: 248 QQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQ 307 Query: 1011 PPAVHGL------------AVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQP 1058 PP V+ A +P PP + + Q PQ QQ Sbjct: 308 PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ-PPVQPQVQQQ 366 Query: 1059 AGAPQPG----AVPPGVPP-----PGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSP 1109 A Q V PGV P PSP QTP SM P P S PG + P Sbjct: 367 QTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP-SPQPGQPSSQP 425 Query: 1110 -----AIVAAVQGNLLPSASPLPDPG---TPLPPDPTAPSPGTV-TPVPP 1150 + A + LPS SP P P + + PSPG + TPV P Sbjct: 426 NSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNP 475 Score = 35.8 bits (81), Expect = 0.24 Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 8/68 (11%) Query: 924 ETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQ 983 +TQ++ ++ L+ ++ + +++ AL+ Q+QQ +Q A+ A QQ FQ Sbjct: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQ--------QQQQQFQAQQSAMQQQFQ 201 Query: 984 QMHQQQQQ 991 + QQQQQ Sbjct: 202 AVVQQQQQ 209 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.129 0.373 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,370,647 Number of Sequences: 37866 Number of extensions: 3644058 Number of successful extensions: 66353 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 794 Number of HSP's successfully gapped in prelim test: 2551 Number of HSP's that attempted gapping in prelim test: 22069 Number of HSP's gapped (non-prelim): 23216 length of query: 1152 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1039 effective length of database: 13,968,660 effective search space: 14513437740 effective search space used: 14513437740 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.