Guide to the Human Genome
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Search of human proteins with 194363725

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194363725 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform c [Homo sapiens]
         (1152 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194363725 SWI/SNF-related matrix-associated actin-dependent r...  2338   0.0  
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re...  2285   0.0  
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...  2171   0.0  
gi|188536047 SWI/SNF-related matrix-associated actin-dependent r...  1337   0.0  
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    76   2e-13
gi|160707881 formin 2 [Homo sapiens]                                   75   3e-13
gi|33356148 formin-like 1 [Homo sapiens]                               75   3e-13
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 74   6e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni...    72   2e-12
gi|57863314 vacuolar protein sorting 37C [Homo sapiens]                72   4e-12
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        70   9e-12
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        70   9e-12
gi|150170670 piccolo isoform 2 [Homo sapiens]                          70   2e-11
gi|150378539 piccolo isoform 1 [Homo sapiens]                          70   2e-11
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    69   2e-11
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     69   3e-11
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     69   3e-11
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    69   3e-11
gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]          68   4e-11
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             67   1e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    67   1e-10
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    66   2e-10
gi|146134388 YLP motif containing 1 [Homo sapiens]                     66   2e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    65   4e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    65   4e-10
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]        65   4e-10
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    65   4e-10
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]    65   4e-10
gi|148536848 carboxyl ester lipase precursor [Homo sapiens]            64   6e-10
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       64   6e-10

>gi|194363725 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform c [Homo sapiens]
          Length = 1152

 Score = 2338 bits (6060), Expect = 0.0
 Identities = 1152/1152 (100%), Positives = 1152/1152 (100%)

Query: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60
            MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
Sbjct: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60

Query: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120
            EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
Sbjct: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120

Query: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180
            VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
Sbjct: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180

Query: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240
            VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
Sbjct: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240

Query: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300
            WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
Sbjct: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300

Query: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360
            RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
Sbjct: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360

Query: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420
            VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
Sbjct: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420

Query: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480
            THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
Sbjct: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480

Query: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540
            LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
Sbjct: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540

Query: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600
            LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP
Sbjct: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600

Query: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660
            TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
Sbjct: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660

Query: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720
            RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
Sbjct: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720

Query: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780
            SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
Sbjct: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780

Query: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840
            RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
Sbjct: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840

Query: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900
            SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
Sbjct: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900

Query: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
            AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
Sbjct: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960

Query: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020
            DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
Sbjct: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
Sbjct: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080

Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140
            PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP
Sbjct: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140

Query: 1141 SPGTVTPVPPPQ 1152
            SPGTVTPVPPPQ
Sbjct: 1141 SPGTVTPVPPPQ 1152


>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform b [Homo sapiens]
          Length = 1130

 Score = 2285 bits (5921), Expect = 0.0
 Identities = 1130/1152 (98%), Positives = 1130/1152 (98%), Gaps = 22/1152 (1%)

Query: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60
            MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
Sbjct: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60

Query: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120
            EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
Sbjct: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120

Query: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180
            VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
Sbjct: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180

Query: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240
            VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
Sbjct: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240

Query: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300
            WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
Sbjct: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300

Query: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360
            RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
Sbjct: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360

Query: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420
            VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
Sbjct: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420

Query: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480
            THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
Sbjct: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480

Query: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540
            LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
Sbjct: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540

Query: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600
            LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP
Sbjct: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600

Query: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660
            TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
Sbjct: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660

Query: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720
            RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
Sbjct: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720

Query: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780
            SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
Sbjct: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780

Query: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840
            RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
Sbjct: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840

Query: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900
            SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
Sbjct: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900

Query: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
            AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
Sbjct: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960

Query: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020
            DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
Sbjct: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
Sbjct: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080

Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140
            PFPNQQTPPSMMPGAVPGSGHPGVA                      DPGTPLPPDPTAP
Sbjct: 1081 PFPNQQTPPSMMPGAVPGSGHPGVA----------------------DPGTPLPPDPTAP 1118

Query: 1141 SPGTVTPVPPPQ 1152
            SPGTVTPVPPPQ
Sbjct: 1119 SPGTVTPVPPPQ 1130


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 2171 bits (5626), Expect = 0.0
 Identities = 1085/1141 (95%), Positives = 1086/1141 (95%), Gaps = 46/1141 (4%)

Query: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60
            MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
Sbjct: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60

Query: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120
            EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
Sbjct: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120

Query: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180
            VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
Sbjct: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180

Query: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240
            VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
Sbjct: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240

Query: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300
            WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
Sbjct: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300

Query: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360
            RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
Sbjct: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360

Query: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420
            VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
Sbjct: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420

Query: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480
            THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
Sbjct: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480

Query: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540
            LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
Sbjct: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540

Query: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600
            LVPLQPKTPQ                               QTSASQQMLNFPDKGKEKP
Sbjct: 541  LVPLQPKTPQ-------------------------------QTSASQQMLNFPDKGKEKP 569

Query: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660
            TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
Sbjct: 570  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 629

Query: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720
            RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
Sbjct: 630  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 689

Query: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780
            SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
Sbjct: 690  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 749

Query: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840
            RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
Sbjct: 750  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 809

Query: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900
            SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
Sbjct: 810  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 869

Query: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
            AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
Sbjct: 870  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 929

Query: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020
            DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
Sbjct: 930  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 989

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
Sbjct: 990  PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1049

Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140
            PFPNQQTPPSMMPGAVPGSGHPGVA  +P                LP  G P PP P AP
Sbjct: 1050 PFPNQQTPPSMMPGAVPGSGHPGVAGNAPL--------------GLPF-GMPPPPPPPAP 1094

Query: 1141 S 1141
            S
Sbjct: 1095 S 1095


>gi|188536047 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c1 [Homo sapiens]
          Length = 1105

 Score = 1337 bits (3461), Expect = 0.0
 Identities = 706/1158 (60%), Positives = 852/1158 (73%), Gaps = 105/1158 (9%)

Query: 4    RKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEV 63
            R+KDGGP  K++E+ +TV+Q D+VR+WLGK+YKKY+ A+ PTNK+L+ LVVQLLQFQE+ 
Sbjct: 32   RRKDGGPATKFWESPETVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDA 91

Query: 64   FGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEM 123
            FGKHV+N   TKLP KCF+DFKAGG+LCHIL AAYK+K++QGWRR+D QNPSRMDRNVEM
Sbjct: 92   FGKHVTNPAFTKLPAKCFMDFKAGGALCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEM 151

Query: 124  FMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYPVPG 183
            FM IEK+LVQNNCL+RPNI+L P+I+ KL  KLKDIIKRHQGT T++K+ ASH +YP   
Sbjct: 152  FMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYSS 211

Query: 184  NLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWIL 243
            + ++EEW+RPVM+++KQVL+HWG+YPDSYDTW+ +++++A +ED P PEKP KVH KWIL
Sbjct: 212  SQDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWIL 271

Query: 244  DTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGG-NYKKRKRS 302
            DTD FNEWMNEEDYEV++++ PVS R++IS K   + V SP+  RRD+K   N +KRK S
Sbjct: 272  DTDIFNEWMNEEDYEVDENRKPVSFRQRISTKN-EEPVRSPE--RRDRKASANARKRKHS 328

Query: 303  PSPSP-TP-EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360
            PSP P TP E++KK+ KKG ++ Y K +    E+EQEDLTKDM++P+PVPN+EEV LPK 
Sbjct: 329  PSPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLTKDMEDPTPVPNIEEVVLPKN 388

Query: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420
            VN KKDSE+ PVKGGT+ DLDEQ++E++   GK++++ +   KG+Q+++ DL EDNVTEQ
Sbjct: 389  VNLKKDSENTPVKGGTVADLDEQDEETVTAGGKEDEDPA---KGDQSRSVDLGEDNVTEQ 445

Query: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480
            T+HIIIPSYA+WFDYN +H IERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
Sbjct: 446  TNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 505

Query: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540
            LTSTACRRNL GDVCA+MRVHAFLEQWGL+NYQVD ESRP  MGPPPT HF+VLADTPSG
Sbjct: 506  LTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSG 565

Query: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600
            LVPL  ++PQ                    VP            A+QQMLNFP+K KEKP
Sbjct: 566  LVPLHLRSPQ--------------------VP------------AAQQMLNFPEKNKEKP 593

Query: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660
             D+QNFGLRTD+Y+KK + +KSK A SA REWTEQETLLLLEALEMYKDDWNKVSEHVGS
Sbjct: 594  VDLQNFGLRTDIYSKKTL-AKSKGA-SAGREWTEQETLLLLEALEMYKDDWNKVSEHVGS 651

Query: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720
            RTQDECILHFLRLPIEDPYLE+S+ASLGPLAYQP+PFSQSGNPVMSTVAFLASVVDPRVA
Sbjct: 652  RTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVA 711

Query: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780
            SAAAK+ALEEFS+++EEVP  LVEAHV+KV+EAA+ +GK DP +GLESS IAGT  DEPE
Sbjct: 712  SAAAKAALEEFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPE 771

Query: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840
            ++E  G +E ++E     ++ E  E +     +E E  E          +K ++G++EK 
Sbjct: 772  KLE--GAEEEKMEADPDGQQPEKAENK-----VENETDEG---------DKAQDGENEKN 815

Query: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGER-----KTKVERDIGEGNLSTAAAA 895
            SEK   D  V  + + E KE +E   KE+ ++  ER     K KVE +I EGN++TAAAA
Sbjct: 816  SEKEQ-DSEVSEDTKSEEKETEEN--KELTDTCKERESDTGKKKVEHEISEGNVATAAAA 872

Query: 896  ALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQR 955
            ALA+AA KAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDRE+EALE QR
Sbjct: 873  ALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQR 932

Query: 956  QQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVH 1015
            QQLL +RQ FHMEQLKYAE+RARQQ  QQ H Q  Q       G   + P GAAG P   
Sbjct: 933  QQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQ-HSGGPGLAPLGAAGHP--- 988

Query: 1016 GLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPG 1075
                            G  P    P   +          Q  P   PQPG +P     PG
Sbjct: 989  ----------------GMMPHQQPPPYPLMH-------HQMPPPHPPQPGQIPG----PG 1021

Query: 1076 PHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPG--TPL 1133
                S  P Q  P  M+P  V  + HP  +  +P  +  + GN+L    PL  P    P 
Sbjct: 1022 ----SMMPGQHMPGRMIP-TVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPP 1076

Query: 1134 PPDPTAPSPGTVTPVPPP 1151
            PP    P P     VPPP
Sbjct: 1077 PPQQQPPPPPPADGVPPP 1094


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
            tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 59/171 (34%), Positives = 65/171 (38%), Gaps = 23/171 (13%)

Query: 986  HQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIG 1045
            HQQQQQPPP  PP  QP PP      P  H     P    P P  S  P  + GP     
Sbjct: 66   HQQQQQPPPQQPPPQQP-PPHQPPPHPQPHQQQQPP----PPPQDSSKPVVAQGP----- 115

Query: 1046 QAGSTAGPQQQQPAGAPQPGAVPP--GVPPPGPHGPSPFPNQ---QTPPSMMPGAVPGSG 1100
              G   G     PA +  P A PP  G PP    GP+P P       PP   P   P SG
Sbjct: 116  --GPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSG 173

Query: 1101 HPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPP 1151
             P    Q+            P+A P P PG    P P  P  G +   P P
Sbjct: 174  VPTTPPQAGGPPPP------PAAVPGPGPGPKQGPGPGGPKGGKMPGGPKP 218



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 61/183 (33%), Positives = 66/183 (36%), Gaps = 23/183 (12%)

Query: 981  HFQQMHQQQQQPPPALPPGSQ-------------PIPPTGAAGPPAVHGLAVAPASVVPA 1027
            H QQ     QQPPP  PP  Q             P PP  ++ P    G   AP      
Sbjct: 66   HQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAP 125

Query: 1028 PAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGP--HGPSPFPNQ 1085
            PA S APP +  P       GS  GP    P   P   + PPG PPP P   G    P Q
Sbjct: 126  PASSSAPPAT--PPTSGAPPGSGPGP---TPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ 180

Query: 1086 QTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLP-PDPTAPSPGT 1144
               P   P AVPG G PG   Q P       G +     P   PG   P   P  P  G 
Sbjct: 181  AGGPPPPPAAVPGPG-PG-PKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGG 238

Query: 1145 VTP 1147
              P
Sbjct: 239  GEP 241



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 53/162 (32%), Positives = 57/162 (35%), Gaps = 35/162 (21%)

Query: 1011 PPAVHGLAVAPASVVPAPAGSGA-PPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPP 1069
            PP   GL      + P P  SG  PP    P  Q          QQQ P   P P   PP
Sbjct: 34   PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQ---------QQQQPPPQQPPPQQPPP 84

Query: 1070 GVPPPGPHGPSPFPNQQTPP----------SMMPGAVPGSGHPGVAAQSPAIVAAVQGNL 1119
              PPP P    P   QQ PP          +  PG  PG G    A+ S           
Sbjct: 85   HQPPPHPQ---PHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGA 141

Query: 1120 LPSASPLPDPGTPLP---------PDPTAPSPGTVTPVPPPQ 1152
             P + P P P TP P         P PT PS G   P  PPQ
Sbjct: 142  PPGSGPGPTP-TPPPAVTSAPPGAPPPTPPSSGV--PTTPPQ 180



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 49/158 (31%), Positives = 56/158 (35%), Gaps = 39/158 (24%)

Query: 984  QMHQQQQQPPP---------ALPPGSQP----IPPTGAAGPPAVHGLAVAPA------SV 1024
            Q HQQQQ PPP         A  PG  P     PP  ++ PPA    + AP       + 
Sbjct: 92   QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTP 151

Query: 1025 VPAPAGSGAPPGS---LGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP------------- 1068
             P PA + APPG+     PS  +      AG     PA  P PG  P             
Sbjct: 152  TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGK 211

Query: 1069 -PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSG---HP 1102
             PG P PG       P     P    G  P  G   HP
Sbjct: 212  MPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP 249



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 37/125 (29%), Positives = 45/125 (36%), Gaps = 8/125 (6%)

Query: 1033 APPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP--- 1089
            +PP  +G ++  G  G   G    +P   P P       PPP    P   P  Q PP   
Sbjct: 33   SPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQ 92

Query: 1090 ---SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVT 1146
                  P   P      V AQ P     V G+  P++S  P    P    P    PG  T
Sbjct: 93   PHQQQQPPPPPQDSSKPVVAQGPGPAPGV-GSAPPASSSAPPATPPTSGAPPGSGPGP-T 150

Query: 1147 PVPPP 1151
            P PPP
Sbjct: 151  PTPPP 155



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 36/108 (33%), Positives = 40/108 (37%), Gaps = 12/108 (11%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPA-GSGAPPGSLGPS--EQIGQAG 1048
            PPP  P    P  P  A GPP        P + VP P  G    PG  GP   +  G   
Sbjct: 165  PPPTPPSSGVPTTPPQAGGPPP-------PPAAVPGPGPGPKQGPGPGGPKGGKMPGGPK 217

Query: 1049 STAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQ--QTPPSMMPG 1094
               GP    P G P+P     G P  G     P+  Q  Q PP   PG
Sbjct: 218  PGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPG 265


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 59/171 (34%), Positives = 70/171 (40%), Gaps = 22/171 (12%)

Query: 992  PPPALP-PGSQPIPPTGAAG---PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PPP LP  G  P PP   AG   PP + G+ + P   +P   G+G PP    P   I   
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP---GAGIPPPPPLPGAGIPPP 1132

Query: 1048 GSTAGPQQQQPAGAPQPGAVPP------GVPPPGPHGPSPFPNQQTPPSMMPGA--VPGS 1099
                G     P   P+ G  PP      G+PPP P   +  P    PP  +PG    P  
Sbjct: 1133 PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP----PPPPLPGVGIPPPP 1188

Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150
              PGV    P     + G  +P   PLP  G P  P P  P PGT  P PP
Sbjct: 1189 PLPGVGIPPP---PPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPP 1236



 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 62/192 (32%), Positives = 76/192 (39%), Gaps = 41/192 (21%)

Query: 991  QPPPA-----LPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP------GSLG 1039
            QPPP      LPP   P+P  G   PP + G  + P   +P   G+G PP       ++ 
Sbjct: 898  QPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLP---GAGIPPPPPLPGAAIP 954

Query: 1040 PSEQIGQAGSTAGPQQQQPAGAPQPGAVP-PGVPPPGP------HGPSPFPNQQTPPSMM 1092
            P   +  AG    P     AG P P  +P  G+PPP P        P P P    PP   
Sbjct: 955  PPPPLPGAGIPL-PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--- 1010

Query: 1093 PGAVPGSG------HPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP-------DPTA 1139
            P  +PG+G       PG     P     + G  +P   PLP  G P PP        P  
Sbjct: 1011 PPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1067

Query: 1140 PSPGTVTPVPPP 1151
            P PG   P PPP
Sbjct: 1068 PLPGAGIPPPPP 1079



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 63/197 (31%), Positives = 73/197 (37%), Gaps = 43/197 (21%)

Query: 992  PPPALP-PGSQPIPPTGAAG---PPAVHGLAVAPASVVPAPA--------GSGAPPGSLG 1039
            PPP LP  G  P+PP   AG   PP + G A+ P   +P           G+G PP    
Sbjct: 922  PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981

Query: 1040 PSEQIGQAGSTAGPQQQQPAGAPQPGAVPP------GVPPPGP------HGPSPFPNQQT 1087
            P   I       G     P   P  G  PP      G+PPP P        P P P    
Sbjct: 982  PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1041

Query: 1088 PPSMMPGAVPGSG------HPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP------ 1135
            PP   P  +PG+G       PG     P     + G  +P   PLP  G P PP      
Sbjct: 1042 PP---PPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1095

Query: 1136 -DPTAPSPGTVTPVPPP 1151
              P  P PG   P PPP
Sbjct: 1096 IPPPPPLPGVGIPPPPP 1112



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 60/182 (32%), Positives = 71/182 (39%), Gaps = 35/182 (19%)

Query: 992  PPPALP----PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PPP LP    P   P+P  G   PP + G  + P   +P   G+G PP    P   I   
Sbjct: 977  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---GAGIPPPPPLPGAGIPPP 1033

Query: 1048 GSTAGPQQQQPAGAPQPGAVPP------GVPPPGP------HGPSPFPNQQTPPSMMPGA 1095
                G     P   P  G  PP      G+PPP P        P P P    PP   P  
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---PPP 1090

Query: 1096 VPGSGHP------GVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149
            +PG+G P      GV    P     + G  +P   PLP  G  +PP P  P PG   P P
Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPP---PLPGAGIPPPPPLPGAG--IPPPP--PLPGAGIPPP 1143

Query: 1150 PP 1151
            PP
Sbjct: 1144 PP 1145



 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 61/189 (32%), Positives = 71/189 (37%), Gaps = 38/189 (20%)

Query: 992  PPPALPPGS-QPIPPTGAAG---PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PPP LP  +  P PP   AG   PP + G  + P   +P   G+G PP    P   I   
Sbjct: 944  PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP---GAGIPPPPPLPGAGIPPP 1000

Query: 1048 GSTAGPQQQQPAGAPQPGAVPP------GVPPPGP------HGPSPFPNQQTPPSMMPGA 1095
                G     P   P  G  PP      G+PPP P        P P P    PP   P  
Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---PPP 1057

Query: 1096 VPGSG------HPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP-------DPTAPSP 1142
            +PG+G       PG     P     + G  +P   PLP  G P PP        P  P P
Sbjct: 1058 LPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1114

Query: 1143 GTVTPVPPP 1151
            G   P PPP
Sbjct: 1115 GAGIPPPPP 1123



 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 50/157 (31%), Positives = 59/157 (37%), Gaps = 50/157 (31%)

Query: 992  PPPALP----PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PPP LP    P   P+P  G   PP + G  + P   +P   G+G PP            
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP---GAGIPP------------ 1175

Query: 1048 GSTAGPQQQQPAGAPQPGAVP-PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAA 1106
                 P      G P P  +P  G+PP     P P P    PP   P  +PG G P    
Sbjct: 1176 -----PPPLPGVGIPPPPPLPGVGIPP-----PPPLPGAGIPP---PPPLPGMGIP---- 1218

Query: 1107 QSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPG 1143
              PA            A PLP PGT +PP P  P  G
Sbjct: 1219 --PA-----------PAPPLPPPGTGIPPPPLLPVSG 1242



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 80/333 (24%), Positives = 124/333 (37%), Gaps = 56/333 (16%)

Query: 844  SDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVK 903
            S G P   P++E   ++ + E    V E+  +R   V++++ +               +K
Sbjct: 624  SMGPPSKPPDEEHRLEDAETESQSAVSETPQKRSDAVQKEVVD---------------MK 668

Query: 904  AKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQ 963
            ++  A V ++  +++  L   T++ +LE   R +  L+T +    + LE     + A   
Sbjct: 669  SEGQATVIQQLEQTIEDL--RTKIAELE---RQYPALDTEVASGHQGLE---NGVTASGD 720

Query: 964  AFHMEQLKYAEMRARQQHFQQMHQQQQQPPP-----ALPP-----GSQPIPPTGAAGPPA 1013
               +E L+  E   R     +    Q  P        LPP     G  P PP   +GP  
Sbjct: 721  VC-LEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQT 779

Query: 1014 VHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPG--- 1070
                  +  S++ +P        S  P++ I Q      P     AG  QPG+ PP    
Sbjct: 780  KF---CSEISLIVSPRRISVQLDSHQPTQSISQPPPP--PSLLWSAGQGQPGSQPPHSIS 834

Query: 1071 --VPPPGPHG-PSPFPNQQTPPSMMP-------GAVPGSGHPGVAAQSPAIVAAVQGNLL 1120
                    H   S F N    PS  P        ++PG G   V    P +       L 
Sbjct: 835  TEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGM--VPPPPPPLPGMTVPTLP 892

Query: 1121 PSASPLPDP--GTPLPPDPTAPSPGTVTPVPPP 1151
             +A P P P  GT + P P  P PG   P PPP
Sbjct: 893  STAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPP 925



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 52/224 (23%), Positives = 81/224 (36%), Gaps = 37/224 (16%)

Query: 954  QRQQLLAD-RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPP 1012
            +++ LL+D +QA  ++Q        +QQ   Q+  QQQQ    L    +P  P  A  P 
Sbjct: 191  EQEDLLSDIQQAIRLQQ--------QQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQ 242

Query: 1013 AVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAG---STAGPQQQQPAGAPQPGAVP- 1068
                L +    + P+  G+G  PGS    + +        +   + ++P   P PG +P 
Sbjct: 243  PGAFLGLDRFLLGPS-GGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPV 301

Query: 1069 ------PGVPPPGPHGPS----PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGN 1118
                  P   P     PS    PFP            V G+G      +  A   A +G+
Sbjct: 302  SEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGS 361

Query: 1119 LLPSASPLPDPGTPLP-----------PDPTAPSPGTVTPVPPP 1151
              P     P+ G   P             P AP+  ++   P P
Sbjct: 362  --PGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 72/253 (28%), Positives = 92/253 (36%), Gaps = 55/253 (21%)

Query: 920  ALLVETQMKKLEIKLRHFEELET----IMDREREALEYQRQQLLADRQAFHMEQLKYAEM 975
            ALL +T+ K     L H EEL+     + +R R+A      ++    +     + +   +
Sbjct: 386  ALLEDTETKNAV--LEHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQARKELETL 443

Query: 976  RARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAA----------------GPPAVHGLAV 1019
            R R      M   ++ P P   P + P  P+                   GP     + +
Sbjct: 444  RERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEI 503

Query: 1020 APASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQ-QPAGAPQPGAVPPGVPPPGPHG 1078
             P +V     G    PG             T  P     PA  P PGA PP  PPP P  
Sbjct: 504  LPVAVATPSGGDAPTPGV-----------PTGSPSPDLAPAAEPAPGAAPPP-PPPLPGL 551

Query: 1079 PSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPT 1138
            PSP   Q+ PPS  P A P  G P                  P A PLP    P PP P 
Sbjct: 552  PSP---QEAPPSAPPQAPPLPGSPEP----------------PPAPPLPGD-LPPPPPPP 591

Query: 1139 APSPGTVTPVPPP 1151
             P PGT  PVPPP
Sbjct: 592  PPPPGTDGPVPPP 604



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 37/110 (33%), Positives = 46/110 (41%), Gaps = 13/110 (11%)

Query: 999  GSQPIP--PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQ 1056
            G  P P  PTG+  P       +APA+  PAP  +  PP  L       +A  +A PQ  
Sbjct: 514  GDAPTPGVPTGSPSPD------LAPAAE-PAPGAAPPPPPPLPGLPSPQEAPPSAPPQAP 566

Query: 1057 QPAGAPQPGAVPPGV----PPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP 1102
               G+P+P   PP      PPP P  P P  +   PP   P   P  G P
Sbjct: 567  PLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPP 616



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 36/121 (29%), Positives = 43/121 (35%), Gaps = 14/121 (11%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051
            P P L P ++P P      PP + GL     +   AP  +   PGS  P       G   
Sbjct: 526  PSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLP 585

Query: 1052 GPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAV---PGSGHPGVAAQS 1108
             P    P      G VPP  PPP P           PP   P A+        PGV A+ 
Sbjct: 586  PPPPPPPPPPGTDGPVPPPPPPPPP-----------PPGGPPDALGRRDSELGPGVKAKK 634

Query: 1109 P 1109
            P
Sbjct: 635  P 635



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 25/64 (39%), Positives = 29/64 (45%), Gaps = 9/64 (14%)

Query: 991  QPPPALP-PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049
            +PPPA P PG  P PP     PP   G       V P P     PPG  GP + +G+  S
Sbjct: 573  EPPPAPPLPGDLPPPPPPPPPPPGTDG------PVPPPPPPPPPPPG--GPPDALGRRDS 624

Query: 1050 TAGP 1053
              GP
Sbjct: 625  ELGP 628



 Score = 38.1 bits (87), Expect = 0.049
 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 15/121 (12%)

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPF---PNQQTPPSMMPGAV- 1096
            S  +G +     P++  PA   +P A+   V      G       P       ++P AV 
Sbjct: 450  STAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVA 509

Query: 1097 -PGSGH---PGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPD-PTAPSPGTVTPVPPP 1151
             P  G    PGV   SP+       +L P+A P P    P PP  P  PSP    P  PP
Sbjct: 510  TPSGGDAPTPGVPTGSPS------PDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPP 563

Query: 1152 Q 1152
            Q
Sbjct: 564  Q 564


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 88/328 (26%), Positives = 136/328 (41%), Gaps = 39/328 (11%)

Query: 830  EKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNL 889
            ++G + D    SE  DG P    + + +      +  K   ES+G+    V RD GE + 
Sbjct: 242  QRGHDDDVSSTSE-DDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEF--VHRDNGERDN 298

Query: 890  STAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDRERE 949
            +    + L+   V+   +     +K K++  L   T ++ + +++   E    I +  RE
Sbjct: 299  NEEKKSGLS---VRFADMPGKSRKKKKNMKEL---TPLQAMMLRMAGQE----IPEEGRE 348

Query: 950  ALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQ--------QQQQPPPALPPGSQ 1001
              E+       D           AE ++++QH ++ H         QQQ PP ++PP   
Sbjct: 349  VEEFSEDDDEDDSDDSE------AEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402

Query: 1002 PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA 1061
              PP    GPP + G   AP    P P  +G PPG    +    +     G +   P   
Sbjct: 403  QAPPM--PGPPPL-GPPPAPPLRPPGPP-TGLPPGPPPGAPPFLRPPGMPGLRGPLPRLL 458

Query: 1062 PQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLP 1121
            P PG  PPG PP  P GP P      PP   P  +P    PG+    P +   ++  L+P
Sbjct: 459  P-PGP-PPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGM---MRPPLVP 513

Query: 1122 SASPLPDPGTPLPPDPTAPSPGTVTPVP 1149
               P P PG   PP P  P+PG ++  P
Sbjct: 514  PLGPAP-PGL-FPPAP-LPNPGVLSAPP 538



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 73/311 (23%), Positives = 116/311 (37%), Gaps = 58/311 (18%)

Query: 828  DEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEG 887
            D++K  +   + +++KSDG+            +G E V ++     GER    E+  G  
Sbjct: 263  DQDKHDDSTDDSDTDKSDGE-----------SDGDEFVHRD----NGERDNNEEKKSG-- 305

Query: 888  NLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDRE 947
             LS   A     +  K K++     +++  L A+++    +++  + R  EE     D +
Sbjct: 306  -LSVRFADMPGKSRKKKKNM-----KELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDED 359

Query: 948  -REALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPP--GSQPIP 1004
              +  E ++Q     ++  H +    A  + +         Q Q PP   PP  G  P P
Sbjct: 360  DSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAP 419

Query: 1005 PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAG---- 1060
            P    GPP   GL   P    P        PG  GP  ++   G   G     P G    
Sbjct: 420  PLRPPGPPT--GLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPG 477

Query: 1061 ---APQPGAVPPGVPPPGPHG-PSPFPNQQTP---------------PSMMPGAVPGSGH 1101
                P P   PP +PPP P G P P P    P               P+ +P       +
Sbjct: 478  LPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLP-------N 530

Query: 1102 PGVAAQSPAIV 1112
            PGV +  P ++
Sbjct: 531  PGVLSAPPNLI 541



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 37/162 (22%), Positives = 59/162 (36%), Gaps = 29/162 (17%)

Query: 922  LVETQMKKLEIKLRH-FEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRAR-Q 979
            L E  +K    KLR  FE +  + ++E   +  + ++L          +++Y + RA+  
Sbjct: 73   LNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKL----------EVEYEQKRAQLS 122

Query: 980  QHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLG 1039
            Q+F  +   Q     ++P    P  P+                 +   P     PP  L 
Sbjct: 123  QYFDAVKNAQHVEVESIPLPDMPHAPSNIL--------------IQDIPLPGAQPPSILK 168

Query: 1040 PSEQIGQAGSTAGPQQQQPAGAPQ--PGAVPPGVPPPGPHGP 1079
             +   G              G P+  PG  PPG PPPGP  P
Sbjct: 169  KTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPG-PPPGPPPP 209



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 29/80 (36%), Positives = 31/80 (38%), Gaps = 14/80 (17%)

Query: 1073 PPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTP 1132
            P  PH PS    Q  P   +PGA P S     +A  P   A        S  PL   G P
Sbjct: 142  PDMPHAPSNILIQDIP---LPGAQPPSILKKTSAYGPPTRAV-------SILPLLGHGVP 191

Query: 1133 -LPPDPTAPSPGTVTPVPPP 1151
             LPP    P P    P PPP
Sbjct: 192  RLPPGRKPPGP---PPGPPP 208


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 59/178 (33%), Positives = 70/178 (39%), Gaps = 40/178 (22%)

Query: 992  PPPALPPGSQPIP----PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PP A PP  +  P    P  A  PPA    +       P+P G+  PP +  PS +    
Sbjct: 942  PPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK---- 997

Query: 1048 GSTAGPQQQQPAGAPQPGAVPPGVPPPGPHG---PSPFP-NQQTPPSMMPGAVPGSGHPG 1103
                GP    P GAP     PP V PP P G    +PFP    TPP+  P +  G     
Sbjct: 998  ---GGPATPSPKGAP----TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG----- 1045

Query: 1104 VAAQSPAIVAAVQGNLLPSASPLPDP----------GTPLPPDPTAPSP--GTVTPVP 1149
                SPA     +G     A+ LP P          G P PP  T PSP  G  TP P
Sbjct: 1046 ----SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099



 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 58/177 (32%), Positives = 71/177 (40%), Gaps = 29/177 (16%)

Query: 992  PPPALP--PGSQPIPPTGAAGPPAVHGLAVAPASV---------VPAPAGSGAPPGSLGP 1040
            PP   P  P + P  P G    P+  G    PA+           P+P G+   P +  P
Sbjct: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGP----SPFPNQQTPPSMMPG-A 1095
            S +    G  A P    P GAP   A  P  P  GP  P    +P P   TPPS+  G A
Sbjct: 1227 SPK----GGLATP---SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279

Query: 1096 VPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152
             P    P   A +PA+V        P+ S  P  G P PP  T PSP      PPP+
Sbjct: 1280 TP----PHKGAPNPAVVTPPSPKGGPATS--PPKGAPTPPAATPPSPKGSPGTPPPK 1330



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 63/190 (33%), Positives = 76/190 (40%), Gaps = 37/190 (19%)

Query: 992  PPPALPPGSQPIP----PTGAAGPPAVHGLAV--APASVVPAPAGSGAPPGSLGPSEQIG 1045
            PP A PP  +  P    P GA  PPAV   +   +PA+  P P G+  PP +  PS +  
Sbjct: 988  PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT-PFPKGASTPPAATPPSPKGS 1046

Query: 1046 QAGS-----------------TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS----PFPN 1084
             A +                   GP      GAP P A  P  P  GP  PS    P P 
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106

Query: 1085 QQTPPSMMPGAV--PGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSP 1142
              TPPS   G    P  G P   A +P    + +G L   A+P P  G P  P  T PSP
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATP---PSPKGGL---ATP-PPKGAPTTPAATPPSP 1159

Query: 1143 GTVTPVPPPQ 1152
                  PPP+
Sbjct: 1160 KGGLATPPPK 1169



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 56/167 (33%), Positives = 65/167 (38%), Gaps = 24/167 (14%)

Query: 997  PPGSQPIPPTGA-AGPPAVHGLAVAPASVVPAPAGSGAPPGSLG-PSEQIGQAGST-AGP 1053
            PP + P  P G+ A  P   G    PA+ +P+P G  A P   G P+       S   GP
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094

Query: 1054 QQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP----SMMPGAVPGSGHPGVAAQSP 1109
                P GAP    +PP   PP P G        TPP       P A P S   G+A   P
Sbjct: 1095 ATPSPKGAP----MPPAATPPSPKG-----GLATPPHKGAPTTPAATPPSPKGGLATPPP 1145

Query: 1110 AIVAAVQGNLLPS-----ASPLPDPGTPLPPDPTAPSP--GTVTPVP 1149
                       PS     A+P P  G P  P  T PSP  G  TP P
Sbjct: 1146 KGAPTTPAATPPSPKGGLATP-PPKGAPTTPAATPPSPKGGLATPSP 1191



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 62/178 (34%), Positives = 74/178 (41%), Gaps = 25/178 (14%)

Query: 992  PPPALPPGSQ---PIPPTGAAGP-----PAVHGLAVAP--ASVVPAPAGSGAPPGSLG-P 1040
            PP   P  S    P P  G A P     PA+   + +P  A   PAP G  A P   G P
Sbjct: 881  PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAP 940

Query: 1041 SEQIGQAGS-TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS----PFPNQQTPPSMMPGA 1095
            +       S   GP    P  AP P A  P  P  GP  PS    P P   TPPS  P  
Sbjct: 941  TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS--PKG 998

Query: 1096 VPGSGHPGVAAQSPAIV-AAVQGNLLPSASPLPDPGTPLPPDPTAPSP---GTVTPVP 1149
             P +  P  A   PA+   + +G+  P+A+P P  G   PP  T PSP      TP+P
Sbjct: 999  GPATPSPKGAPTPPAVTPPSPKGS--PAATPFP-KGASTPPAATPPSPKGSPAATPLP 1053



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 59/184 (32%), Positives = 69/184 (37%), Gaps = 27/184 (14%)

Query: 986  HQQQQQPPPALPP----GSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS 1041
            H+     P A PP    G    PP GA   PA    +       P P G+   P +  PS
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181

Query: 1042 EQIGQAGSTAGPQQQQPAGAP-QPGAVPP----GVPPPGPHGPSPFPNQQTPPSMMPG-A 1095
             +    G  A P    P GAP  P A PP    G+  P P G +P     TPPS   G A
Sbjct: 1182 PK----GGLATP---SPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLA 1233

Query: 1096 VPG-SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTP--------LPPDPTAPSPGTVT 1146
             P   G P   A +P           P  +P P   TP         PP   AP+P  VT
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293

Query: 1147 PVPP 1150
            P  P
Sbjct: 1294 PPSP 1297



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 55/186 (29%), Positives = 67/186 (36%), Gaps = 31/186 (16%)

Query: 992  PPPALPPGSQPIP----PTGAAGPPAV--------------HGLAVAPASVVPAPAGSGA 1033
            PP A PP  +  P    P GA  PPA                G    PA+  P+P G  A
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141

Query: 1034 PPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSM 1091
             P    P +      +   P  +     P P   P  P   PP P G    P+ +  P+ 
Sbjct: 1142 TP----PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT- 1196

Query: 1092 MPGAVPGSGHPGVAAQSPAIVAAVQGNLLPS-----ASPLPDPGTPLPPDPTAPSPGTVT 1146
             P A P S   G+A  SP           PS     A+P P  G P  P  T PSP    
Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGP 1255

Query: 1147 PVPPPQ 1152
              PPP+
Sbjct: 1256 ATPPPK 1261



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 54/171 (31%), Positives = 66/171 (38%), Gaps = 30/171 (17%)

Query: 993  PPALPPGSQPIPPTGAAGPPAV------HGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQ 1046
            PP+   G    PP GA  PPA        GLA  P    P PA    PP   G       
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA-VVTPPSPKG------- 1299

Query: 1047 AGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAA 1106
                 GP    P GAP P A  P  P   P  P P     TPP++ P +  G+  P + A
Sbjct: 1300 -----GPATSPPKGAPTPPAATPPSPKGSPGTPPP-KGAPTPPAVTPPSPKGT--PTLPA 1351

Query: 1107 QSPAIVAAVQGNLLPSASPLPDPGTPLP-----PDPTAPSPGTVTPVPPPQ 1152
             +P   ++  G   PS+   P P    P     P  T PSP     +P P+
Sbjct: 1352 TTP---SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 57/180 (31%), Positives = 69/180 (38%), Gaps = 24/180 (13%)

Query: 992  PPPALP-PGSQPIPPT--GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA- 1047
            P   LP P   P  P+  GA  PPA    +       P+P G+  PP +  PS + G A 
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119

Query: 1048 ----GSTAGPQQQQPA-----GAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSMMPGAV 1096
                G+   P    P+       P P   P  P   PP P G    P  +  P+  P A 
Sbjct: 1120 PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT-TPAAT 1178

Query: 1097 PGSGHPGVAAQSPAIVAAVQGNLLPS-----ASPLPDPGTPLPPDPTAPSP--GTVTPVP 1149
            P S   G+A  SP           PS     A+P P  G P  P  T PSP  G  TP P
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGLATPSP 1237



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 54/183 (29%), Positives = 69/183 (37%), Gaps = 27/183 (14%)

Query: 988  QQQQPPPALPPGSQPIPPTGAAGPPAVHGLA----VAPASVVPAPAGSGAPPGSLGP--- 1040
            Q  +  PA      P  P GA  P AV  L+      P    P P+    P    GP   
Sbjct: 844  QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903

Query: 1041 -----------SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP 1089
                       S    +A +T  P+    + +P+    PP   PP P G    P+ +  P
Sbjct: 904  APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963

Query: 1090 SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDP-GTPLPPDPT-APSPGTVTP 1147
            +  P A P S   G A  SP      +G   P A+  P P G P  P P  AP+P  VTP
Sbjct: 964  TP-PAATPPSPKGGPATPSP------KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP 1016

Query: 1148 VPP 1150
              P
Sbjct: 1017 PSP 1019



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 58/163 (35%), Positives = 64/163 (39%), Gaps = 28/163 (17%)

Query: 1004 PPT--GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA 1061
            PPT  G+AGP    G   +P S V A   S  P  SL          +T  P    P GA
Sbjct: 808  PPTKKGSAGPDTPIGNLSSPVSPVEA---SFLPENSLSFQGSKDSPATTHSPTPPSPKGA 864

Query: 1062 PQPGAV----PPGVPPPGPHGPS------PFPNQ--QTP-PSMMPGAVPGSGHPGVAAQS 1108
            P P AV    P GV  P    P+      PFP +   TP P   P     S  P  A  +
Sbjct: 865  PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARAT 924

Query: 1109 PAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSP--GTVTPVP 1149
            PA            ASP P  G P PP  T PSP  G  TP P
Sbjct: 925  PAPKGI-------PASPSP-KGAPTPPAATPPSPKGGPATPSP 959



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 50/173 (28%), Positives = 63/173 (36%), Gaps = 18/173 (10%)

Query: 992  PPPALPPGSQPIP----PTGAAGPPAV-----HGLAVAPASVVPAPAGSGAPPGSLGPSE 1042
            PP A PP  +  P    P GA  PPAV      G    PA+   +  G   P    GP+ 
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371

Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPP--GPHGPSPFPNQQTPPSMMPGAVPGSG 1100
                     GP    P  +P+ G   P +P P   P  P+  P         P    G+ 
Sbjct: 1372 PAATPSHKGGPAMTPP--SPKRG---PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA 1426

Query: 1101 HPGVAAQSPAIVAAVQGNLLPSAS-PLPDPGTPLPP-DPTAPSPGTVTPVPPP 1151
             P     +P  V  V     P+ S P   P TP    DPT P+    +P  PP
Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 53/175 (30%), Positives = 68/175 (38%), Gaps = 22/175 (12%)

Query: 997  PPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQ 1056
            PP + P  P G+ G P   G    PA   P+P G+   P +  PS + G    ++     
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT-PSSKGGPTTPSSKEGPT 1370

Query: 1057 QPAGAPQ----PGAVPPGVPPPGPHGPSPFPNQQTPPSMMP------GAVP----GSGHP 1102
             PA  P     P   PP  P  GP  PSP     T P+++P       A P    G+  P
Sbjct: 1371 PPAATPSHKGGPAMTPPS-PKRGPAIPSP-KGDPTSPAVIPLSPKKAPATPVTREGAATP 1428

Query: 1103 GVAAQSPAIVAAVQGNLLPSAS-PLPDPGTPLPP-DPTAPS---PGTVTPVPPPQ 1152
                 +P  V  V     P+ S P   P TP    DPT P+   P    P  P Q
Sbjct: 1429 SKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 46/170 (27%), Positives = 62/170 (36%), Gaps = 15/170 (8%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSL--GPSEQIGQAGSTA 1051
            P LP  + P P    A        +   A   PAP G+   P  +   P E      S  
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524

Query: 1052 GP--------QQQQPAG-APQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP 1102
             P         ++ PA  AP+   +PP +  P P      P  +  P+  P +   S  P
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT-PSSKEASSPP 1583

Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPDPG-TPLPPDPTAPSP--GTVTPVP 1149
             V   +     + +  L+P A   P P   P PP  T PSP  G  TP P
Sbjct: 1584 AVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 50/159 (31%), Positives = 60/159 (37%), Gaps = 33/159 (20%)

Query: 994  PALP-PGSQPIPPTG--AAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050
            PA+P P   P  P+   A+ PPAV       A   P+P     PP    PS         
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGA---PSPKELLIPPAVTSPS--------- 1609

Query: 1051 AGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPA 1110
                   P  AP P AV P  P  GP  P+P     +PP + P ++  S        SPA
Sbjct: 1610 -------PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP-VTPSSLKDS------PTSPA 1655

Query: 1111 IVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149
             V    G  +P AS     G P    PTA     V P P
Sbjct: 1656 SVTCKMGATVPQAS----KGLPAKKGPTALKEVLVAPAP 1690



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 50/200 (25%), Positives = 75/200 (37%), Gaps = 42/200 (21%)

Query: 993  PPALPP----GSQPIPPTGAAGP--PAVHGLAVAPASVVPAPAGSGAPP----GSLGPSE 1042
            PPA  P    G    PP+   GP  P+  G   +PA +  +P  + A P    G+  PS+
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK 1430

Query: 1043 -----------QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSM 1091
                        + +A +T+ P+      + +     P V PP P  P P P +Q   S 
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP-PAP-KQVATSS 1488

Query: 1092 MPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTP------------------- 1132
             P   P +  P  A   PA++ +    +  + S   DP  P                   
Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548

Query: 1133 LPPDPTAPSPGTVTPVPPPQ 1152
            +PP  T PSP     +P P+
Sbjct: 1549 IPPAMTVPSPKKTPAIPTPK 1568



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 21/174 (12%)

Query: 991  QPPPALPPGSQPIP---PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            QP P LPP   P P   P  AA   +      +P+++   P     P  S G +  +G A
Sbjct: 40   QPGPTLPPPCSPAPQQCPLSAANQASPF---PSPSTIASTPLEVPFPQSSSGTALPLGTA 96

Query: 1048 --GSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMM---PGAVPGSG-- 1100
                T  P    P  +P   A+   +  P   G    P+   P +++   P +V  S   
Sbjct: 97   PEAPTFLPNLIGPPISPAALALASPMIAPTLKGT---PSSSAPLALVALAPHSVQKSSAF 153

Query: 1101 HPGVAAQSPAIVAAVQGNLLPSASPL--PDPGTPL--PPDPTAPSPGTVTPVPP 1150
             P +    P++  A  G+++  ++P+   +P T L   P    P+P   TP PP
Sbjct: 154  PPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNP-KGTPSPP 206



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 46/177 (25%), Positives = 64/177 (36%), Gaps = 30/177 (16%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051
            PP   PPG++ +   G +   A+  +A +P       +G+ A   S G    +  + S  
Sbjct: 740  PPAGTPPGTKKVD--GISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPL 797

Query: 1052 G----PQQQQP------AGAPQP-GAVPPGVPPPG----PHGPSPFPNQQTPPSMMPGAV 1096
            G    PQ ++P      AG   P G +   V P      P     F   +  P+      
Sbjct: 798  GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857

Query: 1097 PGS--GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSP--GTVTPVP 1149
            P S  G P  +A +P         L P    LP   TP P     P P  G  TP P
Sbjct: 858  PPSPKGAPTPSAVTP---------LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP 905



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 51/192 (26%), Positives = 64/192 (33%), Gaps = 39/192 (20%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVV-----PAPAGSGAPPGSLGP------ 1040
            P P   P S P+ P+     P       +PASV        P  S   P   GP      
Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPT------SPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684

Query: 1041 -------SEQIGQAGSTAGPQQQQ-----PAGAPQPGAVPPGVPPPGPHGPSPF-PNQQT 1087
                   S  I  A +  GPQ ++     P   P P A      P     P+P  P Q+ 
Sbjct: 1685 LVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744

Query: 1088 PPSMMPG-----AVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPD--PTAP 1140
                  G     +  G   P  +  S  + AA    +LP          P PP   P AP
Sbjct: 1745 SSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP 1804

Query: 1141 SPGTVTPVPPPQ 1152
            SP  V  +PP Q
Sbjct: 1805 SP--VPTLPPKQ 1814


>gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
          Length = 355

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 59/174 (33%), Positives = 71/174 (40%), Gaps = 26/174 (14%)

Query: 987  QQQQQPPPALPPGSQPIPPTGA--AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQI 1044
            ++Q QPP A+PP   P  P+ +   GP A   L  AP  VV  P+    P G   P+ Q+
Sbjct: 191  EEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQL 250

Query: 1045 G---QAGSTAGPQQQQPAGAPQP----GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVP 1097
            G    AG +  PQ+  P     P    GA  PG P  G   PSP   QQ+P     G  P
Sbjct: 251  GPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPP 310

Query: 1098 GSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPL-PPDPTAPSPGTVTPVPP 1150
                P                 LPS    P P  PL PP P  P+P    P PP
Sbjct: 311  YPIQP----------------QLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPP 348



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 42/137 (30%), Positives = 49/137 (35%), Gaps = 31/137 (22%)

Query: 992  PPPALPPGSQP---------IPPTGAAGPPAVHGLAVAPA-SVVPAPAGSGAPPGSLGPS 1041
            PP   P  SQP           P    GP    G + +P  S+ P P   G P G+ GP 
Sbjct: 224  PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPG 283

Query: 1042 EQI--GQAGSTAGPQQQ-------------QPAGAPQPGAVPPGVPPPGPHGPSPFPNQQ 1086
              +  G+A S   PQQ              QP     PG   P VP   P+ P P P   
Sbjct: 284  YPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYG 343

Query: 1087 TPPSMMPGAVPGSGHPG 1103
             PP       PG   PG
Sbjct: 344  FPPP------PGPAWPG 354



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 45/140 (32%), Positives = 55/140 (39%), Gaps = 20/140 (14%)

Query: 1029 AGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP----PGVP-PPGPHG---PS 1080
            AG   PP    P   + Q       +Q QP  A  P  +P    P +P  P  HG   P+
Sbjct: 167  AGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPA 226

Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPD-PGTPL----PP 1135
            PFP   + PS   G + G  +P  A   P   A    +   S  P P  PGTP+    P 
Sbjct: 227  PFP-VVSQPSFYSGPL-GPTYP-AAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPG 283

Query: 1136 DP----TAPSPGTVTPVPPP 1151
             P     APSPG     P P
Sbjct: 284  YPLRGGRAPSPGYPQQSPYP 303


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 61/173 (35%), Positives = 66/173 (38%), Gaps = 22/173 (12%)

Query: 989  QQQPPPALPPGSQPIPPT----GAAGPPAVHGLA--VAPASVVPAPAGSGAP--PGSLGP 1040
            Q  P P   PG Q  P      G  GPP + GL   + P          G P  PG LGP
Sbjct: 422  QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSG 1100
                G+ G       Q P G P  G     + PPG  GP   P    PP       PG G
Sbjct: 482  K---GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGF-----PGIG 533

Query: 1101 HPGVAA-QSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152
             PGVA    P       G L P   P   PG P PP P  P P  + P PPPQ
Sbjct: 534  KPGVAGLHGP---PGKPGALGPQGQP-GLPGPPGPPGPPGP-PAVMPPTPPPQ 581



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 57/189 (30%), Positives = 70/189 (37%), Gaps = 30/189 (15%)

Query: 991  QPPPALPPGSQPIP-PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049
            QP P    G + +P P G  GP    G  +  A  V  P G   PPG +G    +G+ G 
Sbjct: 218  QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG-LPGVGKPGV 276

Query: 1050 TAGPQQQQPAGAP----QPGAV----------PPGVPPPGPHGPSPFPNQQTPPSMM--- 1092
            T  P  Q P G P    +PG            PPG+P  G  G    P Q   P      
Sbjct: 277  TGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQ 336

Query: 1093 -------PGAVPGSGHPGV-AAQSPAIVAAVQGNLLP--SASPLPDPGTPLPPDPTAPSP 1142
                   P  +PG G PG    +    +  V G L P     P+  PG   PP      P
Sbjct: 337  GLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPG-LP 395

Query: 1143 GTVTPVPPP 1151
            G   P+ PP
Sbjct: 396  GIPGPMGPP 404



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 51/182 (28%), Positives = 62/182 (34%), Gaps = 23/182 (12%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLG---PSEQIGQA 1047
            +P P  PPG   +P  G  G     G    P    P   G    PG++G      +IGQ 
Sbjct: 125  EPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQK 184

Query: 1048 GSTAGPQQQQPAGAPQPGAVP-------PGVP----PPGPHGPSPFPNQQ-------TPP 1089
            G         P G P P  +P       PG+P    P G  GP   P  Q          
Sbjct: 185  GEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG 244

Query: 1090 SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149
              MPGA    G PG+    P     + G   P  +  P P  PL        PG   P+ 
Sbjct: 245  FGMPGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302

Query: 1150 PP 1151
             P
Sbjct: 303  VP 304



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 49/147 (33%), Positives = 57/147 (38%), Gaps = 12/147 (8%)

Query: 988  QQQQPPPALPP---GSQPIPPTGAAGP---PAVHGLAVAPASVVPAPAGSGAPPGSLGPS 1041
            Q  Q PP +P     S PI P G  GP   P + G    P    P  AG   PPG  G  
Sbjct: 491  QGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGAL 550

Query: 1042 EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPP-GPHGPS-PFPNQQTPPSMMPGAVPGS 1099
               GQ G    P    P G P P AV P  PPP G + P          P    GA  G 
Sbjct: 551  GPQGQPGLPGPPG---PPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGK 607

Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPL 1126
             + G A + PA  A +     P  +P+
Sbjct: 608  -NGGPAYEMPAFTAELTAPFPPVGAPV 633



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 44/158 (27%), Positives = 54/158 (34%), Gaps = 14/158 (8%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGP 1053
            P  P G       G  GPP + G+            G G  PG+LGP    G+ G    P
Sbjct: 327  PGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPR---GEKGPIGAP 383

Query: 1054 QQQQPAGAPQPGAVPPGVPP------PGPHGPSPFPNQQTPPSMM--PGAVPGSGHPGVA 1105
                P G P    +P  + P      PGP G       Q PP     PG     G PG  
Sbjct: 384  GIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFL 443

Query: 1106 AQ-SPAIVAAVQGNLLP--SASPLPDPGTPLPPDPTAP 1140
             +  P  +  + G + P   A     PG P  P    P
Sbjct: 444  GEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 49/180 (27%), Positives = 61/180 (33%), Gaps = 25/180 (13%)

Query: 991  QPPPALPPGSQPIPPTGAAGPP---AVHGLAVAPASVVPAPAGSGAP--PGSLGPSEQIG 1045
            Q PP +PP      P G   P    A  GLA+    +     G   P  P  +   +   
Sbjct: 39   QIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGK-EMPHLQYGKEYPHLPQYMKEIQPAP 97

Query: 1046 QAGSTAGPQ------------QQQPAGAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSM 1091
            + G  A P+            +Q P G P P   P  PG+P  G  G    P  Q  P +
Sbjct: 98   RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV 157

Query: 1092 MPGAVPG-SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150
                +PG  G PG      A     Q        P+  PG   PP P    PG   P  P
Sbjct: 158  GKPGMPGMPGKPGAMGMPGAKGEIGQKG---EIGPMGIPGPQGPPGPHG-LPGIGKPGGP 213


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 61/173 (35%), Positives = 66/173 (38%), Gaps = 22/173 (12%)

Query: 989  QQQPPPALPPGSQPIPPT----GAAGPPAVHGLA--VAPASVVPAPAGSGAP--PGSLGP 1040
            Q  P P   PG Q  P      G  GPP + GL   + P          G P  PG LGP
Sbjct: 422  QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSG 1100
                G+ G       Q P G P  G     + PPG  GP   P    PP       PG G
Sbjct: 482  K---GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGF-----PGIG 533

Query: 1101 HPGVAA-QSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152
             PGVA    P       G L P   P   PG P PP P  P P  + P PPPQ
Sbjct: 534  KPGVAGLHGP---PGKPGALGPQGQP-GLPGPPGPPGPPGP-PAVMPPTPPPQ 581



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 57/189 (30%), Positives = 70/189 (37%), Gaps = 30/189 (15%)

Query: 991  QPPPALPPGSQPIP-PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049
            QP P    G + +P P G  GP    G  +  A  V  P G   PPG +G    +G+ G 
Sbjct: 218  QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG-LPGVGKPGV 276

Query: 1050 TAGPQQQQPAGAP----QPGAV----------PPGVPPPGPHGPSPFPNQQTPPSMM--- 1092
            T  P  Q P G P    +PG            PPG+P  G  G    P Q   P      
Sbjct: 277  TGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQ 336

Query: 1093 -------PGAVPGSGHPGV-AAQSPAIVAAVQGNLLP--SASPLPDPGTPLPPDPTAPSP 1142
                   P  +PG G PG    +    +  V G L P     P+  PG   PP      P
Sbjct: 337  GLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPG-LP 395

Query: 1143 GTVTPVPPP 1151
            G   P+ PP
Sbjct: 396  GIPGPMGPP 404



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 51/182 (28%), Positives = 62/182 (34%), Gaps = 23/182 (12%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLG---PSEQIGQA 1047
            +P P  PPG   +P  G  G     G    P    P   G    PG++G      +IGQ 
Sbjct: 125  EPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQK 184

Query: 1048 GSTAGPQQQQPAGAPQPGAVP-------PGVP----PPGPHGPSPFPNQQ-------TPP 1089
            G         P G P P  +P       PG+P    P G  GP   P  Q          
Sbjct: 185  GEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG 244

Query: 1090 SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149
              MPGA    G PG+    P     + G   P  +  P P  PL        PG   P+ 
Sbjct: 245  FGMPGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302

Query: 1150 PP 1151
             P
Sbjct: 303  VP 304



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 49/147 (33%), Positives = 57/147 (38%), Gaps = 12/147 (8%)

Query: 988  QQQQPPPALPP---GSQPIPPTGAAGP---PAVHGLAVAPASVVPAPAGSGAPPGSLGPS 1041
            Q  Q PP +P     S PI P G  GP   P + G    P    P  AG   PPG  G  
Sbjct: 491  QGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGAL 550

Query: 1042 EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPP-GPHGPS-PFPNQQTPPSMMPGAVPGS 1099
               GQ G    P    P G P P AV P  PPP G + P          P    GA  G 
Sbjct: 551  GPQGQPGLPGPPG---PPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGK 607

Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPL 1126
             + G A + PA  A +     P  +P+
Sbjct: 608  -NGGPAYEMPAFTAELTAPFPPVGAPV 633



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 44/158 (27%), Positives = 54/158 (34%), Gaps = 14/158 (8%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGP 1053
            P  P G       G  GPP + G+            G G  PG+LGP    G+ G    P
Sbjct: 327  PGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPR---GEKGPIGAP 383

Query: 1054 QQQQPAGAPQPGAVPPGVPP------PGPHGPSPFPNQQTPPSMM--PGAVPGSGHPGVA 1105
                P G P    +P  + P      PGP G       Q PP     PG     G PG  
Sbjct: 384  GIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFL 443

Query: 1106 AQ-SPAIVAAVQGNLLP--SASPLPDPGTPLPPDPTAP 1140
             +  P  +  + G + P   A     PG P  P    P
Sbjct: 444  GEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 49/180 (27%), Positives = 61/180 (33%), Gaps = 25/180 (13%)

Query: 991  QPPPALPPGSQPIPPTGAAGPP---AVHGLAVAPASVVPAPAGSGAP--PGSLGPSEQIG 1045
            Q PP +PP      P G   P    A  GLA+    +     G   P  P  +   +   
Sbjct: 39   QIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGK-EMPHLQYGKEYPHLPQYMKEIQPAP 97

Query: 1046 QAGSTAGPQ------------QQQPAGAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSM 1091
            + G  A P+            +Q P G P P   P  PG+P  G  G    P  Q  P +
Sbjct: 98   RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV 157

Query: 1092 MPGAVPG-SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150
                +PG  G PG      A     Q        P+  PG   PP P    PG   P  P
Sbjct: 158  GKPGMPGMPGKPGAMGMPGAKGEIGQKG---EIGPMGIPGPQGPPGPHG-LPGIGKPGGP 213


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 60/187 (32%), Positives = 70/187 (37%), Gaps = 30/187 (16%)

Query: 990  QQP----PPALPPGSQ--PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPG------- 1036
            QQP    PP  PPG+   P  P G A PPA    +  P+S  P P     PPG       
Sbjct: 344  QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403

Query: 1037 SLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP-PGVPPPGPHGPSPFPNQQT-------- 1087
              GP++   Q   T  P  QQP G   P   P P   P    GP   P QQ         
Sbjct: 404  QPGPAKPPTQQVGTPKPLAQQP-GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462

Query: 1088 ------PPSMMPG-AVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140
                  PPS +PG A P    PG A   P    + +       S  P P  P P  P+  
Sbjct: 463  QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522

Query: 1141 SPGTVTP 1147
             PG+  P
Sbjct: 523  QPGSTKP 529



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 62/190 (32%), Positives = 72/190 (37%), Gaps = 31/190 (16%)

Query: 990  QQPPPALPPGSQP---IPPTGAAGPPA-----VHGLAVAPASVVPA--PAGSGAPPGS-L 1038
            QQP P  PP  QP       G A PPA        LA  P +V P   P G+  PP   L
Sbjct: 307  QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366

Query: 1039 GPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-----PPPGPHGP------SPFPNQQT 1087
            GP++   Q   +  P  +QP   P+  A PPGV       PGP  P      +P P  Q 
Sbjct: 367  GPAKPPAQQTGSEKPSSEQPG--PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424

Query: 1088 PPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPD----PTAPSPG 1143
            P    P   PG     V    P  + A Q    P  +     G   PP     P  P P 
Sbjct: 425  PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG--PGKTSAQQTGPTKPPSQLPGPAKPPPQ 482

Query: 1144 TVTPV-PPPQ 1152
               P  PPPQ
Sbjct: 483  QPGPAKPPPQ 492



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 58/182 (31%), Positives = 67/182 (36%), Gaps = 29/182 (15%)

Query: 990  QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASV-----------VPAP-AGSGA---- 1033
            QQP PA PP  Q   P   A  P +   A AP              +PA  AG G     
Sbjct: 403  QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462

Query: 1034 ------PPGSL-GPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-PPPGPHGPSPFPNQ 1085
                  PP  L GP++   Q    A P  QQP  A  P   P    PPP   GP+    Q
Sbjct: 463  QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522

Query: 1086 QTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTV 1145
            Q   +  P   PGS  P     SPA  +A Q     S  P+   G+  P  P   SP   
Sbjct: 523  QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ-----STKPVSQTGSGKPLQPPTVSPSAK 577

Query: 1146 TP 1147
             P
Sbjct: 578  QP 579



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 62/204 (30%), Positives = 73/204 (35%), Gaps = 46/204 (22%)

Query: 992  PPPALPPGSQPIP-------------PTGAAGPPA-----VHGLAVAPASVVP--APAGS 1031
            P P+ PP  QP P               G A PPA        LA  P +V P   P G+
Sbjct: 299  PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT 358

Query: 1032 GAPPGS-LGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-----PPPGPHGP------ 1079
              PP   LGP++   Q   +  P  +QP   P+  A PPGV       PGP  P      
Sbjct: 359  TKPPAQPLGPAKPPAQQTGSEKPSSEQP--GPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416

Query: 1080 SPFPNQQTP----------PSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDP 1129
            +P P  Q P          P+  P   PG G        P   +A Q       S LP P
Sbjct: 417  TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476

Query: 1130 GTPLP--PDPTAPSPGTVTPVPPP 1151
              P P  P P  P P       PP
Sbjct: 477  AKPPPQQPGPAKPPPQQPGSAKPP 500



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 53/160 (33%), Positives = 60/160 (37%), Gaps = 39/160 (24%)

Query: 990  QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049
            QQP PA PP  QP    G+A PP+       P S  P P      PG   PS Q  Q GS
Sbjct: 482  QQPGPAKPPPQQP----GSAKPPSQQ-----PGSTKPPP----QQPGPAKPSPQ--QPGS 526

Query: 1050 TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSP 1109
            T  P Q       QPG+  P    P P  PS         S  P +  GSG P    Q P
Sbjct: 527  TKPPSQ-------QPGSAKPSAQQPSPAKPS------AQQSTKPVSQTGSGKP---LQPP 570

Query: 1110 AIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149
             +         PSA   P  G P    P   +   +  VP
Sbjct: 571  TV--------SPSAKQPPSQGLPKTICPLCNTTELLLHVP 602



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 42/141 (29%), Positives = 58/141 (41%), Gaps = 17/141 (12%)

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            PAS +P    SG+P  S  P++      S++     QP   P P   PP  PPP P  P 
Sbjct: 2372 PASQLP----SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP--PPPPPPPPP 2425

Query: 1081 PFPNQQTP-PSMMPGAVPGSGHPGVAAQSPAI--------VAAVQGNLLPSASPLPDPGT 1131
            P P   +P P+++P        P V   +P           A ++ N LP          
Sbjct: 2426 PLPPPTSPKPTILPKKKLTVASP-VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPP 2484

Query: 1132 PLPPDPTA-PSPGTVTPVPPP 1151
            P+PP P++ PS    T  P P
Sbjct: 2485 PVPPKPSSIPSGLVFTHRPEP 2505



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 42/167 (25%), Positives = 60/167 (35%), Gaps = 15/167 (8%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP--------GSLGPSE 1042
            QPPP  PP   P PP     PP +        +++P    + A P         ++   E
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE 2463

Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPG---PHGPSPFPNQQTPPSMMPGAVPGS 1099
                  S   P  +    AP P    P   P G    H P P      P  ++P     +
Sbjct: 2464 TTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTT 2523

Query: 1100 GHPGVAAQSP---AIVAAVQGNLLPSAS-PLPDPGTPLPPDPTAPSP 1142
              P      P   ++ +++  NL+ SA   LP P +PL P     SP
Sbjct: 2524 QKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSP 2570



 Score = 38.1 bits (87), Expect = 0.049
 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 17/120 (14%)

Query: 984  QMHQQQQQPPPALPPGSQP---IPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040
            Q   +++  PP     ++P    PPTG    P         +  +P PA         GP
Sbjct: 784  QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-------DSKAIPRPASDSKIISHPGP 836

Query: 1041 S------EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTP-PSMMP 1093
            S      +Q+        P++ Q   +P+P A P     P P GP P   Q  P P   P
Sbjct: 837  SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 39/150 (26%), Positives = 51/150 (34%), Gaps = 27/150 (18%)

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPP----------- 1069
            P+SV+  P             E  GQ      P  Q P+G+P   ++P            
Sbjct: 2344 PSSVIALPMKEQLSTTYFTSGETFGQEK----PASQLPSGSPSVSSLPAKPRPFFRSSSL 2399

Query: 1070 --GVPPPGPHGPSPFPNQQTPPSMMPG-AVPGSGHPGVAAQSPAIVAAVQGNLLPSASPL 1126
                 PP P  P P P    PP   P    P S  P +  +    VA+     + +A+PL
Sbjct: 2400 DISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP----VTTATPL 2455

Query: 1127 PDPGTPLPPDPTAPSPG-----TVTPVPPP 1151
             D  T L       S G       T  PPP
Sbjct: 2456 FDAVTTLETTAVLRSNGLPVTRICTTAPPP 2485



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 35/163 (21%), Positives = 63/163 (38%), Gaps = 22/163 (13%)

Query: 717  PRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAG--- 773
            P   S       E+   + E +   + E  +++ +E  K T K D    + SS       
Sbjct: 1438 PHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS 1497

Query: 774  ------TTSDEP-ERIEESGNDE----------ARVEGQATDEKKEPKEPREGGGAIEEE 816
                  TT  EP + +EES   E            V   ++DE K+  E  +G G  E+ 
Sbjct: 1498 EFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ--EDSQGSGEEEDF 1555

Query: 817  AKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPK 859
             +++  E    ++  G E D    ++  +     + +K++E K
Sbjct: 1556 IRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETK 1598



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 4/72 (5%)

Query: 1085 QQTPPSMMPGAVPG----SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140
            Q+ P S +P   P        P    +S ++  + Q    P   P P P  P PP P  P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428

Query: 1141 SPGTVTPVPPPQ 1152
             P +  P   P+
Sbjct: 2429 PPTSPKPTILPK 2440


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 60/187 (32%), Positives = 70/187 (37%), Gaps = 30/187 (16%)

Query: 990  QQP----PPALPPGSQ--PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPG------- 1036
            QQP    PP  PPG+   P  P G A PPA    +  P+S  P P     PPG       
Sbjct: 344  QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403

Query: 1037 SLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP-PGVPPPGPHGPSPFPNQQT-------- 1087
              GP++   Q   T  P  QQP G   P   P P   P    GP   P QQ         
Sbjct: 404  QPGPAKPPTQQVGTPKPLAQQP-GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462

Query: 1088 ------PPSMMPG-AVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140
                  PPS +PG A P    PG A   P    + +       S  P P  P P  P+  
Sbjct: 463  QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522

Query: 1141 SPGTVTP 1147
             PG+  P
Sbjct: 523  QPGSTKP 529



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 62/190 (32%), Positives = 72/190 (37%), Gaps = 31/190 (16%)

Query: 990  QQPPPALPPGSQP---IPPTGAAGPPA-----VHGLAVAPASVVPA--PAGSGAPPGS-L 1038
            QQP P  PP  QP       G A PPA        LA  P +V P   P G+  PP   L
Sbjct: 307  QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366

Query: 1039 GPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-----PPPGPHGP------SPFPNQQT 1087
            GP++   Q   +  P  +QP   P+  A PPGV       PGP  P      +P P  Q 
Sbjct: 367  GPAKPPAQQTGSEKPSSEQPG--PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424

Query: 1088 PPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPD----PTAPSPG 1143
            P    P   PG     V    P  + A Q    P  +     G   PP     P  P P 
Sbjct: 425  PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG--PGKTSAQQTGPTKPPSQLPGPAKPPPQ 482

Query: 1144 TVTPV-PPPQ 1152
               P  PPPQ
Sbjct: 483  QPGPAKPPPQ 492



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 58/182 (31%), Positives = 67/182 (36%), Gaps = 29/182 (15%)

Query: 990  QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASV-----------VPAP-AGSGA---- 1033
            QQP PA PP  Q   P   A  P +   A AP              +PA  AG G     
Sbjct: 403  QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462

Query: 1034 ------PPGSL-GPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-PPPGPHGPSPFPNQ 1085
                  PP  L GP++   Q    A P  QQP  A  P   P    PPP   GP+    Q
Sbjct: 463  QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522

Query: 1086 QTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTV 1145
            Q   +  P   PGS  P     SPA  +A Q     S  P+   G+  P  P   SP   
Sbjct: 523  QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ-----STKPVSQTGSGKPLQPPTVSPSAK 577

Query: 1146 TP 1147
             P
Sbjct: 578  QP 579



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 62/204 (30%), Positives = 73/204 (35%), Gaps = 46/204 (22%)

Query: 992  PPPALPPGSQPIP-------------PTGAAGPPA-----VHGLAVAPASVVP--APAGS 1031
            P P+ PP  QP P               G A PPA        LA  P +V P   P G+
Sbjct: 299  PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT 358

Query: 1032 GAPPGS-LGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-----PPPGPHGP------ 1079
              PP   LGP++   Q   +  P  +QP   P+  A PPGV       PGP  P      
Sbjct: 359  TKPPAQPLGPAKPPAQQTGSEKPSSEQP--GPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416

Query: 1080 SPFPNQQTP----------PSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDP 1129
            +P P  Q P          P+  P   PG G        P   +A Q       S LP P
Sbjct: 417  TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476

Query: 1130 GTPLP--PDPTAPSPGTVTPVPPP 1151
              P P  P P  P P       PP
Sbjct: 477  AKPPPQQPGPAKPPPQQPGSAKPP 500



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 53/160 (33%), Positives = 60/160 (37%), Gaps = 39/160 (24%)

Query: 990  QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049
            QQP PA PP  QP    G+A PP+       P S  P P      PG   PS Q  Q GS
Sbjct: 482  QQPGPAKPPPQQP----GSAKPPSQQ-----PGSTKPPP----QQPGPAKPSPQ--QPGS 526

Query: 1050 TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSP 1109
            T  P Q       QPG+  P    P P  PS         S  P +  GSG P    Q P
Sbjct: 527  TKPPSQ-------QPGSAKPSAQQPSPAKPS------AQQSTKPVSQTGSGKP---LQPP 570

Query: 1110 AIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149
             +         PSA   P  G P    P   +   +  VP
Sbjct: 571  TV--------SPSAKQPPSQGLPKTICPLCNTTELLLHVP 602



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 42/141 (29%), Positives = 58/141 (41%), Gaps = 17/141 (12%)

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            PAS +P    SG+P  S  P++      S++     QP   P P   PP  PPP P  P 
Sbjct: 2372 PASQLP----SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP--PPPPPPPPP 2425

Query: 1081 PFPNQQTP-PSMMPGAVPGSGHPGVAAQSPAI--------VAAVQGNLLPSASPLPDPGT 1131
            P P   +P P+++P        P V   +P           A ++ N LP          
Sbjct: 2426 PLPPPTSPKPTILPKKKLTVASP-VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPP 2484

Query: 1132 PLPPDPTA-PSPGTVTPVPPP 1151
            P+PP P++ PS    T  P P
Sbjct: 2485 PVPPKPSSIPSGLVFTHRPEP 2505



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 42/167 (25%), Positives = 60/167 (35%), Gaps = 15/167 (8%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP--------GSLGPSE 1042
            QPPP  PP   P PP     PP +        +++P    + A P         ++   E
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE 2463

Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPG---PHGPSPFPNQQTPPSMMPGAVPGS 1099
                  S   P  +    AP P    P   P G    H P P      P  ++P     +
Sbjct: 2464 TTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTT 2523

Query: 1100 GHPGVAAQSP---AIVAAVQGNLLPSAS-PLPDPGTPLPPDPTAPSP 1142
              P      P   ++ +++  NL+ SA   LP P +PL P     SP
Sbjct: 2524 QKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSP 2570



 Score = 38.1 bits (87), Expect = 0.049
 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 17/120 (14%)

Query: 984  QMHQQQQQPPPALPPGSQP---IPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040
            Q   +++  PP     ++P    PPTG    P         +  +P PA         GP
Sbjct: 784  QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-------DSKAIPRPASDSKIISHPGP 836

Query: 1041 S------EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTP-PSMMP 1093
            S      +Q+        P++ Q   +P+P A P     P P GP P   Q  P P   P
Sbjct: 837  SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 39/150 (26%), Positives = 51/150 (34%), Gaps = 27/150 (18%)

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPP----------- 1069
            P+SV+  P             E  GQ      P  Q P+G+P   ++P            
Sbjct: 2344 PSSVIALPMKEQLSTTYFTSGETFGQEK----PASQLPSGSPSVSSLPAKPRPFFRSSSL 2399

Query: 1070 --GVPPPGPHGPSPFPNQQTPPSMMPG-AVPGSGHPGVAAQSPAIVAAVQGNLLPSASPL 1126
                 PP P  P P P    PP   P    P S  P +  +    VA+     + +A+PL
Sbjct: 2400 DISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP----VTTATPL 2455

Query: 1127 PDPGTPLPPDPTAPSPG-----TVTPVPPP 1151
             D  T L       S G       T  PPP
Sbjct: 2456 FDAVTTLETTAVLRSNGLPVTRICTTAPPP 2485



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 35/163 (21%), Positives = 63/163 (38%), Gaps = 22/163 (13%)

Query: 717  PRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAG--- 773
            P   S       E+   + E +   + E  +++ +E  K T K D    + SS       
Sbjct: 1438 PHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS 1497

Query: 774  ------TTSDEP-ERIEESGNDE----------ARVEGQATDEKKEPKEPREGGGAIEEE 816
                  TT  EP + +EES   E            V   ++DE K+  E  +G G  E+ 
Sbjct: 1498 EFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ--EDSQGSGEEEDF 1555

Query: 817  AKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPK 859
             +++  E    ++  G E D    ++  +     + +K++E K
Sbjct: 1556 IRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETK 1598



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 4/72 (5%)

Query: 1085 QQTPPSMMPGAVPG----SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140
            Q+ P S +P   P        P    +S ++  + Q    P   P P P  P PP P  P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428

Query: 1141 SPGTVTPVPPPQ 1152
             P +  P   P+
Sbjct: 2429 PPTSPKPTILPK 2440


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 105/475 (22%), Positives = 171/475 (36%), Gaps = 70/475 (14%)

Query: 731  FSKMKEEVPTALVEAHVRKVEEAAKVTG---KADPAFGLESSGIAGTTSDEPERIEE--- 784
            F+KM +E    +V      V    KV      +D +    S   + T   E ER +    
Sbjct: 454  FAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAE 513

Query: 785  ---------------SGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDE 829
                           S   + + + +  D+K++ KE  +    +EE  K K  E P K  
Sbjct: 514  LQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKT 573

Query: 830  EKGKEGDS-----EKESEKSDGDPIVDPEKEKEPK----EGQEEVLKEVVESEGERKTKV 880
            +K    +S     E    KS   P  + E+E + K    E + ++  ++ +  GE+  +V
Sbjct: 574  KKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRV 633

Query: 881  ERDIG--EGNLSTAAAAALAAAAVKAKHLAAVE-ERKIKSLVALLVETQMKKLEI----- 932
               I   E +L  +    +       K     E ER + S +    + Q +K+++     
Sbjct: 634  VHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSS 693

Query: 933  KLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQP 992
            K++ F   E+    E  + + +     ++ +     + K    R +++H    HQQ QQ 
Sbjct: 694  KMKGFSSSESESSSESSSSDSED----SETEMAPKSKKKGHPGREQKKHHHHHHQQMQQA 749

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVP--------APAGSGAPPGSLGPSEQI 1044
            P  +P   QP PP     PP        P    P        APA   +PP  +     +
Sbjct: 750  PAPVP--QQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV 807

Query: 1045 ------GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQ--TPPSMMPGAV 1096
                  G      G   Q     PQP  +PP +P P  H   P  NQ     P  +  A+
Sbjct: 808  LEPQLPGSVFDPIGHFTQPILHLPQP-ELPPHLPQPPEHSTPPHLNQHAVVSPPALHNAL 866

Query: 1097 P---------GSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSP 1142
            P          +  P   A+ PA+  A+    L    P+  P   L  D   P+P
Sbjct: 867  PQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAP 921



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 13/148 (8%)

Query: 1016 GLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPG 1075
            G A    S VP    +  PP +  P        +T  P             V   VPP  
Sbjct: 187  GTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246

Query: 1076 PHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQG-------NLLPSASPLPD 1128
               P P P Q  PP   P   P   HP + A +P  V   +G           +  P+ +
Sbjct: 247  LQTPPPVPPQPQPPPA-PAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHE 305

Query: 1129 PGTPLPPDPTAPSPG----TVTPVPPPQ 1152
            P + LPP+P     G    +  PV PP+
Sbjct: 306  PPS-LPPEPKTTKLGQRRESSRPVKPPK 332



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 55/212 (25%), Positives = 70/212 (33%), Gaps = 41/212 (19%)

Query: 981  HFQQ--MHQQQQQPPPALP-PGSQPIPPT----GAAGPPAVHG-LAVAP-------ASVV 1025
            HF Q  +H  Q + PP LP P     PP         PPA+H  L   P       A++ 
Sbjct: 822  HFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALP 881

Query: 1026 PAPAGSGAPPGSLGPSEQIGQAGSTAGPQ----QQQPAGAP-----------QPGAVPPG 1070
            P PA   A   +L  +  + Q      PQ     ++P   P           Q   V P 
Sbjct: 882  PKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941

Query: 1071 VP----------PPGPHGPSPFPN-QQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNL 1119
             P          PP P  P P P+ QQ      P   P    P    Q       V    
Sbjct: 942  TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQP 1001

Query: 1120 LPSASPLPDPGTPLPPDPTAPSPGTVTPVPPP 1151
            +  ++ +  P  P    P  P PG   P P P
Sbjct: 1002 MQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQP 1033



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 42/155 (27%), Positives = 50/155 (32%), Gaps = 26/155 (16%)

Query: 981  HFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040
            H     Q QQQPPP  PP  QP P      PP                      P  L P
Sbjct: 963  HPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR---------------------PVHLQP 1001

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSG 1100
             +          PQ QQP   P PG  P   PPP P  P         P         +G
Sbjct: 1002 MQFSTHIQQPPPPQGQQPP-HPPPGQQP---PPPQPAKPQQVIQHHHSPRHHKSDPYSTG 1057

Query: 1101 HPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP 1135
            H    A SP ++ + Q +   S +    P   + P
Sbjct: 1058 HLR-EAPSPLMIHSPQMSQFQSLTHQSPPQQNVQP 1091



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 34/151 (22%), Positives = 65/151 (43%), Gaps = 18/151 (11%)

Query: 846  GDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAA-----LAAA 900
            G P++ P ++  P  G  +  K+  + E +     ++D+   N+ + A+         ++
Sbjct: 1158 GRPVIRPPEQNAPPPGAPD--KDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSS 1215

Query: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
              K+   +  + R+     A   E + K L+ +  H E       +E+E L  +R +   
Sbjct: 1216 TAKSSSDSFEQFRR----AAREKEEREKALKAQAEHAE-------KEKERLRQERMRSRE 1264

Query: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQ 991
            D  A    +  + E R RQ+  QQ  Q+QQQ
Sbjct: 1265 DEDALEQARRAHEEARRRQEQQQQQRQEQQQ 1295



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 28/92 (30%), Positives = 33/92 (35%), Gaps = 1/92 (1%)

Query: 1060 GAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIV-AAVQGN 1118
            G  + G   PGV        +  P Q   P   P  V  + HP  A     IV   V   
Sbjct: 182  GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTV 241

Query: 1119 LLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150
            + P     P P  P P  P AP+P  V   PP
Sbjct: 242  VPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPP 273



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 58/208 (27%), Positives = 80/208 (38%), Gaps = 40/208 (19%)

Query: 955  RQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAV 1014
            +QQ     +  H++ ++++       H QQ    Q Q PP  PPG QP PP   A P  V
Sbjct: 987  QQQHQPPPRPVHLQPMQFST------HIQQPPPPQGQQPPHPPPGQQP-PPPQPAKPQQV 1039

Query: 1015 HGLAVAPASVVPAPAGSG----APPGSLGPSEQIGQAGS---------TAGPQQQQPAGA 1061
                 +P      P  +G    AP   +  S Q+ Q  S            P++Q+   A
Sbjct: 1040 IQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAA 1099

Query: 1062 ----PQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQG 1117
                PQP  V   V     H P    ++   PS+ P       HP       +I A V  
Sbjct: 1100 SVVQPQPLVV---VKEEKIHSPI-IRSEPFSPSLRP---EPPKHP------ESIKAPVHL 1146

Query: 1118 NLLPSASPLPDPGTPL--PPDPTAPSPG 1143
               P   P+ D G P+  PP+  AP PG
Sbjct: 1147 PQRPEMKPV-DVGRPVIRPPEQNAPPPG 1173



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 47/172 (27%), Positives = 54/172 (31%), Gaps = 40/172 (23%)

Query: 992  PPPALPPGSQP-------IPPTGAAGPPAVHGLAVAPASVVPAPAGSGA----------- 1033
            P PA PP   P       +P    A PP V    +      PAP  +             
Sbjct: 882  PKPARPPAVSPALTQTPLLPQPPMAQPPQV----LLEDEEPPAPPLTSMQMQLYLQQLQK 937

Query: 1034 --PPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSM 1091
              PP  L PS ++        P    P+   Q    PP  PPP P  P   P QQ  P  
Sbjct: 938  VQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPP---PQQQHQPPP 994

Query: 1092 MPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSAS--PLPDPG-TPLPPDPTAP 1140
             P          V  Q       +Q    P     P P PG  P PP P  P
Sbjct: 995  RP----------VHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKP 1036



 Score = 30.8 bits (68), Expect = 7.8
 Identities = 28/123 (22%), Positives = 48/123 (39%), Gaps = 10/123 (8%)

Query: 282 NSPDSDRRDKKGGNYKKRKRSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTK 341
           N P    +DKK    +K KR        E KK  AK+ P     K+   +    +++   
Sbjct: 534 NKPKKKEKDKKEKKKEKHKRK---EEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAP 590

Query: 342 DMDEPSPVPNVEEVTLPKTVNTKK------DSESAP-VKGGTMTDLDEQEDESMETTGKD 394
              +P P    EE    K ++ ++      D    P  K G +  + +  + S++ +  D
Sbjct: 591 MKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPD 650

Query: 395 EDE 397
           E E
Sbjct: 651 EIE 653


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 78/290 (26%), Positives = 113/290 (38%), Gaps = 54/290 (18%)

Query: 903  KAKHLAAVEERKIKSLVALLVETQ--MKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
            K++  AA  E+K+ S +    E Q  MKK+E     FE+    +  E++AL  ++QQ+  
Sbjct: 467  KSEAKAAELEKKLDSELTARHELQVEMKKME---SDFEQKLQDLQGEKDALHSEKQQIAT 523

Query: 961  DRQAFHMEQLKYA--------EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPT----GA 1008
            ++Q    E  +          E+   ++    +       PP++P  + P+PP     G 
Sbjct: 524  EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRA-PVPPAPPLPGD 582

Query: 1009 AG----PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA------------- 1051
            +G    PP   G +  P    P P      PG +  S      G TA             
Sbjct: 583  SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 642

Query: 1052 --GPQQQQPAGAPQPGAVPPG--VPPPGP-HGPSPFPNQQTPPSMMPGAV----PGSGHP 1102
               P   +  G P P ++P G  +PPP P  G +  P    PP  +PG+     P    P
Sbjct: 643  PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP---PPPPPLPGSAGIPPPPPPLP 699

Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPD-PGTPLPPDPTAPSPGTVTPVPPP 1151
            G A   P       G  +P   P P  PG P PP      PG   P PPP
Sbjct: 700  GEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP------PGMGMPPPPP 743



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 67/254 (26%), Positives = 100/254 (39%), Gaps = 28/254 (11%)

Query: 910  VEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQ 969
            +++ K++   A   E + KKL+ +L    EL+  M +     E + Q L  ++ A H E+
Sbjct: 460  IDKTKVEKSEAKAAELE-KKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEK 518

Query: 970  LKYA-EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAG---PPAVHGLA-VAPASV 1024
             + A E +  +    Q+  +  +    L    + +    AA    PP+V   A V PA  
Sbjct: 519  QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPP 578

Query: 1025 VPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHG-----P 1079
            +P  +G+  PP         G + +   P    P   P PG V    PP  P G     P
Sbjct: 579  LPGDSGTIIPPPPAP-----GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPP 633

Query: 1080 SPFPNQQT--PPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDP 1137
             P     T  PP  +P         GV   SP+ +    G  +P   PLP      PP P
Sbjct: 634  PPLSGDATIPPPPPLP--------EGVGIPSPSSLPG--GTAIPPPPPLPGSARIPPPPP 683

Query: 1138 TAPSPGTVTPVPPP 1151
              P    + P PPP
Sbjct: 684  PLPGSAGIPPPPPP 697



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 54/166 (32%), Positives = 60/166 (36%), Gaps = 25/166 (15%)

Query: 992  PPPALPPG----SQPIPPTGAA--GPPAVHGLAVAPASVVPAPAGSGAP-PGSLGPSEQI 1044
            PPP LP G    S P  P G A   PP + G A  P    P P G G P P SL     I
Sbjct: 608  PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPP-PLPEGVGIPSPSSLPGGTAI 666

Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104
                   G  +  P   P PG+     PPP   G +  P    PP  +PG  PG   P  
Sbjct: 667  PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP---PPPPPLPGG-PGIPPPPP 722

Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150
                P I             P P PG  +PP P         PV P
Sbjct: 723  FPGGPGI-------------PPPPPGMGMPPPPPFGFGVPAAPVLP 755


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 78/290 (26%), Positives = 113/290 (38%), Gaps = 54/290 (18%)

Query: 903  KAKHLAAVEERKIKSLVALLVETQ--MKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
            K++  AA  E+K+ S +    E Q  MKK+E     FE+    +  E++AL  ++QQ+  
Sbjct: 476  KSEAKAAELEKKLDSELTARHELQVEMKKME---SDFEQKLQDLQGEKDALHSEKQQIAT 532

Query: 961  DRQAFHMEQLKYA--------EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPT----GA 1008
            ++Q    E  +          E+   ++    +       PP++P  + P+PP     G 
Sbjct: 533  EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRA-PVPPAPPLPGD 591

Query: 1009 AG----PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA------------- 1051
            +G    PP   G +  P    P P      PG +  S      G TA             
Sbjct: 592  SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 651

Query: 1052 --GPQQQQPAGAPQPGAVPPG--VPPPGP-HGPSPFPNQQTPPSMMPGAV----PGSGHP 1102
               P   +  G P P ++P G  +PPP P  G +  P    PP  +PG+     P    P
Sbjct: 652  PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP---PPPPPLPGSAGIPPPPPPLP 708

Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPD-PGTPLPPDPTAPSPGTVTPVPPP 1151
            G A   P       G  +P   P P  PG P PP      PG   P PPP
Sbjct: 709  GEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP------PGMGMPPPPP 752



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 67/254 (26%), Positives = 100/254 (39%), Gaps = 28/254 (11%)

Query: 910  VEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQ 969
            +++ K++   A   E + KKL+ +L    EL+  M +     E + Q L  ++ A H E+
Sbjct: 469  IDKTKVEKSEAKAAELE-KKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEK 527

Query: 970  LKYA-EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAG---PPAVHGLA-VAPASV 1024
             + A E +  +    Q+  +  +    L    + +    AA    PP+V   A V PA  
Sbjct: 528  QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPP 587

Query: 1025 VPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHG-----P 1079
            +P  +G+  PP         G + +   P    P   P PG V    PP  P G     P
Sbjct: 588  LPGDSGTIIPPPPAP-----GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPP 642

Query: 1080 SPFPNQQT--PPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDP 1137
             P     T  PP  +P         GV   SP+ +    G  +P   PLP      PP P
Sbjct: 643  PPLSGDATIPPPPPLP--------EGVGIPSPSSLPG--GTAIPPPPPLPGSARIPPPPP 692

Query: 1138 TAPSPGTVTPVPPP 1151
              P    + P PPP
Sbjct: 693  PLPGSAGIPPPPPP 706



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 54/166 (32%), Positives = 60/166 (36%), Gaps = 25/166 (15%)

Query: 992  PPPALPPG----SQPIPPTGAA--GPPAVHGLAVAPASVVPAPAGSGAP-PGSLGPSEQI 1044
            PPP LP G    S P  P G A   PP + G A  P    P P G G P P SL     I
Sbjct: 617  PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPP-PLPEGVGIPSPSSLPGGTAI 675

Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104
                   G  +  P   P PG+     PPP   G +  P    PP  +PG  PG   P  
Sbjct: 676  PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP---PPPPPLPGG-PGIPPPPP 731

Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150
                P I             P P PG  +PP P         PV P
Sbjct: 732  FPGGPGI-------------PPPPPGMGMPPPPPFGFGVPAAPVLP 764


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
            subunit [Homo sapiens]
          Length = 551

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 56/169 (33%), Positives = 63/169 (37%), Gaps = 24/169 (14%)

Query: 992  PPPALPPG-SQPIPPTGAAGPPAVHGLAVAPASVVPAPA------GSGAPPGSLGPSEQI 1044
            PPP  P G + P PP G  GPP   G    P  V+P P       G   PP  L P +  
Sbjct: 226  PPPPFPAGQTPPRPPLGPPGPPGPPG-PPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPF 284

Query: 1045 GQ---AGSTAGPQQQQPAGAPQPGAVPP--------GVPPPGPHGPSPFPNQQTPPSMMP 1093
            GQ        GP    P   P PG  PP        G  PP P GP   P    PP  +P
Sbjct: 285  GQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLP 344

Query: 1094 GAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSP 1142
            G  PG+  P     +P +  A       S  P  D   P P DP    P
Sbjct: 345  GPPPGAPPP-----APHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPP 388



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 55/174 (31%), Positives = 63/174 (36%), Gaps = 31/174 (17%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052
            P A+P G +   P G  GPP        P      P G   PPG   P + +      AG
Sbjct: 208  PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVL--PPPLAG 265

Query: 1053 PQQQ------------QPAGAPQPGAVPPGVPPPGP-HGPSPFPNQQTPPSMMPGAVPGS 1099
            P  +            QP G P  G +PPG PPP P +GP P P    PP   P   PG 
Sbjct: 266  PPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGP---PPPQQGPPPPPGP 322

Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPV--PPP 1151
              P              G L P  +  P P  P PP    P    V P   PPP
Sbjct: 323  FPP-----------RPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPP 365



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 53/150 (35%), Positives = 60/150 (40%), Gaps = 24/150 (16%)

Query: 1007 GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA--PQP 1064
            G AGPP     A  P        G G  PG++   ++        GP    PAG   P+P
Sbjct: 184  GKAGPPGGSSRAAFPQG----GRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP 239

Query: 1065 GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSAS 1124
               PPG  PPGP GP P P Q  PP       P +G P    + P  V      L P   
Sbjct: 240  PLGPPG--PPGPPGPPP-PGQVLPP-------PLAGPPNRGDRPPPPV------LFPGQP 283

Query: 1125 PLPDPGTPLPPDPTAPSPGTVTP--VPPPQ 1152
                P  PLPP P  P PG   P   PPPQ
Sbjct: 284  FGQPPLGPLPPGPPPPVPGYGPPPGPPPPQ 313



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 36/113 (31%), Positives = 40/113 (35%), Gaps = 25/113 (22%)

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS- 1099
            S +  Q+G  +G  +  P G     A P G       G   F          PGAVPG  
Sbjct: 171  SRKTTQSGQMSGEGKAGPPGGSSRAAFPQG-----GRGRGRF----------PGAVPGGD 215

Query: 1100 ---GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVP 1149
               G  G     P   A       P   PL  PG P PP P  P PG V P P
Sbjct: 216  RFPGPAGPGGPPPPFPA----GQTPPRPPLGPPGPPGPPGP--PPPGQVLPPP 262


>gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]
          Length = 828

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 55/208 (26%), Positives = 91/208 (43%), Gaps = 37/208 (17%)

Query: 324 YTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTKKDSESAPVKGGTMTDLDEQ 383
           ++KS RG  + E++D T    E         +TL     +  D +S         +L++Q
Sbjct: 272 FSKSSRGCLQNEKQDETLSSSE---------ITLWTEKQSNGDKKSI--------ELNDQ 314

Query: 384 EDESMETTGKDEDENSTGNKGEQTKNPD--------------LHEDNVTEQTHH---III 426
           +   +       D         Q  +P+               H   + E++H    +  
Sbjct: 315 KFNELIKNCNKHDGRGIIVDARQLPSPEPCEIQKNLNDNEMLFHSCQMVEESHEEEELKP 374

Query: 427 PSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTAC 486
           P      D N +   E++A+PEFF G+ ++KTPE YL  RN+++D + +   +YL  T+ 
Sbjct: 375 PEQEIEIDRNIIQEEEKQAIPEFFEGR-QAKTPERYLKIRNYILDQWEICKPKYLNKTSV 433

Query: 487 RRNL--AGDVCAIMRVHAFLEQWGLINY 512
           R  L   GDV  I R+H +LE  G IN+
Sbjct: 434 RPGLKNCGDVNCIGRIHTYLELIGAINF 461


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 59/167 (35%), Positives = 74/167 (44%), Gaps = 26/167 (15%)

Query: 983  QQMHQQQQQPPPALPP--GSQ-PIPPT-----GAAGPPAVHGLAVAPASVVPAPAGSGAP 1034
            Q+M +Q+  PPP  P   G+Q P PP      G +GP     L +AP    P P G   P
Sbjct: 305  QEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPP--PTPRGP-PP 361

Query: 1035 PGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGP----HGPSPFPNQQTPPS 1090
            PG  GP      A   +GP    P GA  P   PP  PPP P    +GP+P P    PP+
Sbjct: 362  PGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPP---LPPA 418

Query: 1091 MMP--GAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP 1135
            ++P  G  PG G   +  Q   I   +Q N  P A   P+     PP
Sbjct: 419  LVPAGGLAPGGGRGALLDQ---IRQGIQLNKTPGA---PESSALQPP 459



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 28/123 (22%)

Query: 1034 PPGSLGPSEQ-----IGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTP 1088
            PP S G ++      +G     +GP    P G   P   P G PPPG  GP P P   T 
Sbjct: 317  PPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATG 376

Query: 1089 PS-MMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTP 1147
             S  +P   PG+G P                      P+P P  P PP P++ +     P
Sbjct: 377  RSGPLPPPPPGAGGP----------------------PMPPPPPPPPPPPSSGNGPAPPP 414

Query: 1148 VPP 1150
            +PP
Sbjct: 415  LPP 417



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 9/81 (11%)

Query: 1071 VPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPG 1130
            +PPP P  PS   NQ   P ++ G     G  G     P  +A       P+    P PG
Sbjct: 313  LPPPPP--PSRGGNQLPRPPIVGG---NKGRSGPLPPVPLGIAPPP----PTPRGPPPPG 363

Query: 1131 TPLPPDPTAPSPGTVTPVPPP 1151
               PP P  P+ G   P+PPP
Sbjct: 364  RGGPPPPPPPATGRSGPLPPP 384



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 34/90 (37%), Positives = 40/90 (44%), Gaps = 21/90 (23%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPA--PAGSGAPPGSLGP-SEQIGQAG 1048
            PPP  PP   P PP+   GP        AP  + PA  PAG  AP G  G   +QI Q  
Sbjct: 394  PPP--PPPPPP-PPSSGNGP--------APPPLPPALVPAGGLAPGGGRGALLDQIRQ-- 440

Query: 1049 STAGPQQQQPAGAPQPGAVPPGVPPPGPHG 1078
               G Q  +  GAP+  A+ P  PP    G
Sbjct: 441  ---GIQLNKTPGAPESSALQP--PPQSSEG 465



 Score = 34.3 bits (77), Expect = 0.70
 Identities = 27/83 (32%), Positives = 30/83 (36%), Gaps = 9/83 (10%)

Query: 1070 GVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDP 1129
            G  PP P G +P      PP+      PG G P      P       G L P       P
Sbjct: 340  GPLPPVPLGIAP-----PPPTPRGPPPPGRGGP---PPPPPPATGRSGPLPPPPPGAGGP 391

Query: 1130 GTPLPPDPTAPSPGTVT-PVPPP 1151
              P PP P  P P +   P PPP
Sbjct: 392  PMPPPPPPPPPPPSSGNGPAPPP 414


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 57/168 (33%), Positives = 68/168 (40%), Gaps = 17/168 (10%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAV----APASVVPAPAGSG--APPGSLGPSEQI 1044
            Q PP+ PP S P+ P     P A + LAV    AP S  P+P      +PP S   S   
Sbjct: 631  QAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP-- 687

Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104
                S   P Q  P+ A  P  VPP  P   P  PS  P  Q PP +   A P    P  
Sbjct: 688  ----SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL--AAPPLQVPPSP 741

Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152
             A  P   +A     +P    L  P   +PP P A  P +    PPPQ
Sbjct: 742  PASPPMSPSATPPPRVPPL--LAAPPLQVPPSPPASLPMSPLAKPPPQ 787



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 54/169 (31%), Positives = 65/169 (38%), Gaps = 22/169 (13%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050
            Q PP+ PP S P+ P+    P A   LA  P  V P+P  S  PP S           S 
Sbjct: 705  QVPPS-PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS--PPMS----------PSA 751

Query: 1051 AGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAV-----PGSGHPGVA 1105
              P +  P  A  P  VPP  P   P  P   P  Q PP++    +     P +  PG A
Sbjct: 752  TPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQA 811

Query: 1106 AQSPAIVAAVQGNLLPSASPLPDPGTPL---PPDPTAPSPGTVTPVPPP 1151
              SP+    +     P     P    PL   PP P A SP    P  PP
Sbjct: 812  PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA-SPTLQAPRRPP 859



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 52/176 (29%), Positives = 64/176 (36%), Gaps = 23/176 (13%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050
            + PP   P     PP+    PP        P+S+   P    APP    P  Q G     
Sbjct: 559  ETPPCPAPCPLQAPPSPLTTPPPE-----TPSSIATPPPQ--APPALASPPLQ-GLPSPP 610

Query: 1051 AGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAV-------PGSGHPG 1103
              P    P  AP   A+PP   PP P    P     TP    P A+       P S  P 
Sbjct: 611  LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670

Query: 1104 VAAQSPAIVAAVQGNLLPSASP-------LPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152
               Q+P    A    + PSA+P       L  P   +PP P A  P + +  PPPQ
Sbjct: 671  PPVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 56/167 (33%), Positives = 65/167 (38%), Gaps = 24/167 (14%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050
            Q PP+ PP S P+ P+ A  PP V  L  AP   VP      +PP SL P   + +    
Sbjct: 736  QVPPS-PPASPPMSPS-ATPPPRVPPLLAAPPLQVPP-----SPPASL-PMSPLAKPPPQ 787

Query: 1051 AGPQQQQP--AGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPG--AVPGSGHPGVAA 1106
            A P    P     P P A  PG  P  P    P     TPP   P   A P    P    
Sbjct: 788  APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 847

Query: 1107 QSPAIVAAVQGNLLPSASPLPDPGTPL--PPDPTAPSPGTVTPVPPP 1151
             SP + A       P   P P P T +  P    A +PG   P PPP
Sbjct: 848  ASPTLQA-------PRRPPTPGPDTSVSGPRLTLALAPG---PPPPP 884



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 54/197 (27%), Positives = 67/197 (34%), Gaps = 38/197 (19%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050
            Q PP+ PP S P+ P     P A   LA  P   +P+P  S        PS  +  +   
Sbjct: 767  QVPPS-PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825

Query: 1051 AGPQQQQPAGA-------PQPGAVP----PGVPP-PGP----HGP----SPFPNQQTPPS 1090
              P Q  P  A       P P A P    P  PP PGP     GP    +  P    PPS
Sbjct: 826  TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885

Query: 1091 MMPGAVPG----SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGT-------------PL 1133
              P +       +GH   A  +P  +          A+  P P               P 
Sbjct: 886  RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA 945

Query: 1134 PPDPTAPSPGTVTPVPP 1150
            PP     +PG   P PP
Sbjct: 946  PPLAFRGAPGAPLPWPP 962



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 49/164 (29%), Positives = 60/164 (36%), Gaps = 21/164 (12%)

Query: 995  ALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP----GSLGPSE-QIGQAGS 1049
            +L   S   P +    PP     ++AP S+   PA    PP     SL P   Q   A  
Sbjct: 494  SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553

Query: 1050 TAGPQQQQPAGAPQPGAVPPG-VPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQS 1108
            T    +  P  AP P   PP  +  P P  PS      TPP   P A+           S
Sbjct: 554  TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI---ATPPPQAPPAL----------AS 600

Query: 1109 PAIVAAVQGNLLPSASPLPD--PGTPLPPDPTAPSPGTVTPVPP 1150
            P +       L P A+P P   P   LPP    PSP    P+ P
Sbjct: 601  PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 44/168 (26%), Positives = 61/168 (36%), Gaps = 15/168 (8%)

Query: 989  QQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVV-PAPAGSGA--PPGSLGPSEQIG 1045
            Q+    +L   + P+     +GP A  G   APA    P P G  A  PP    P +   
Sbjct: 235  QRPASRSLSSSATPLSSPARSGPSA-RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD-- 291

Query: 1046 QAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVA 1105
             A    GP    P   P P        PP  +  +P P    P   +   +P      +A
Sbjct: 292  -AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP------LA 344

Query: 1106 AQSPAIVAAVQGNLLPSASP--LPDPGTPLPPDPTAPSPGTVTPVPPP 1151
              SP+   ++Q    P A+P     P    PP    PS  T+ P+  P
Sbjct: 345  PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 41/165 (24%), Positives = 57/165 (34%), Gaps = 26/165 (15%)

Query: 1009 AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS--EQIGQAGSTAGPQQQQPAGAPQPGA 1066
            AG  A    A AP  + P P GS  PP  + P+    +G AG+       + AG      
Sbjct: 10   AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69

Query: 1067 VPPGVPPPGP--------HGPS-------------PFPNQQTPPSMMPGAVPGSGHPGVA 1105
            +P   P  GP          P+             P  N    P   PG   G+  PG  
Sbjct: 70   IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129

Query: 1106 AQSPAIVAAVQGNLLPSASPLPDP---GTPLPPDPTAPSPGTVTP 1147
             Q    ++A +      A+  P           D + P+PGT +P
Sbjct: 130  GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 44/170 (25%), Positives = 61/170 (35%), Gaps = 22/170 (12%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050
            +P P     + P+P T    PP    L +AP            P  S  PS Q   +   
Sbjct: 315  RPVPPPDNAATPLPATLPPSPPLATPLPLAP------------PSPSAPPSLQTLPSPPA 362

Query: 1051 AGPQQQQPAGAPQPGAVPPG---VPP-PGPHGPSPFPNQQTPPSMMP----GAVPGSGHP 1102
              P Q  P+    P   PP    +PP   PH  +  P+ Q PPS +      A    G P
Sbjct: 363  TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS-PSLQAPPSPLALSSLQATTSLGSP 421

Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152
             + A    +  + +       SP     TP P  P   +P ++   PP Q
Sbjct: 422  TLQATHSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQAPLSLPASPPLQ 470



 Score = 34.7 bits (78), Expect = 0.54
 Identities = 42/167 (25%), Positives = 58/167 (34%), Gaps = 38/167 (22%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAV--------APASVVPAPAGSGAPPGSLGPSEQIG 1045
            P  PP   P P T  +GP     LA         +P+S +  P  +G    +    E++ 
Sbjct: 855  PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912

Query: 1046 ------QAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS 1099
                  + G+ A P       A  P A   G  PP     +P      PP+  PG+  G 
Sbjct: 913  GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972

Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP--DPTAPSPGT 1144
                        +   +G         P+  TP P   DP  PSPGT
Sbjct: 973  ----------CTIYETEG---------PESATPAPGALDP-GPSPGT 999


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
          Length = 2524

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 76/367 (20%), Positives = 138/367 (37%), Gaps = 28/367 (7%)

Query: 786  GNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSD 845
            G  + + + Q   ++++ ++P       E++ KEK  EA K++E+   E D E   ++  
Sbjct: 491  GKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKT 550

Query: 846  GDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVKAK 905
             D   +   EKE    +    ++   S+G RK ++ R     +++  A +  A    ++ 
Sbjct: 551  DDTSGEDNDEKEAVASKG---RKTANSQGRRKGRITR-----SMANEANSEEAITPQQSA 602

Query: 906  HLAAVEERKIKSLVALLVETQMKKLEIKLRHFEEL------ETIMDREREALEYQRQQLL 959
             LA++E  +        +ET  K L    R++  +      +T+   +     Y+++Q L
Sbjct: 603  ELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNL 662

Query: 960  AD-RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLA 1018
             +  Q   ++  K    R +++       ++   PP +                 V    
Sbjct: 663  DEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAE 722

Query: 1019 VAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-----PP 1073
               AS    P G  + P ++  S       S   P  +      Q G  PP       PP
Sbjct: 723  ALHASGNEVPRGECSGPATVNNS---SDTESIPSPHTEAAKDTGQNGPKPPATLGADGPP 779

Query: 1074 PGPHGPS----PFPNQQTPPSMMPGA-VPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPD 1128
            PGP  P     P P + TP S   GA  P    P  +A  P +    +     +A P+ +
Sbjct: 780  PGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEE 839

Query: 1129 PGTPLPP 1135
                 PP
Sbjct: 840  GEEQKPP 846



 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 130/652 (19%), Positives = 218/652 (33%), Gaps = 92/652 (14%)

Query: 545  QPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPEL----------------QTSASQQ 588
            Q   P+  Q + D K   K  E ++  PE    K +L                +  AS+ 
Sbjct: 509  QQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKG 568

Query: 589  MLNFPDKGKEK---PTDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALE 645
                  +G+ K      M N     +  T +     +    + +  WTE+E     + L 
Sbjct: 569  RKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGLL 628

Query: 646  MYKDDWNKVSEHVGSRTQDEC---ILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGN 702
             +  +W+ ++  VGS+T  +C     ++ +    D  L+  +  +           ++  
Sbjct: 629  EHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPA 688

Query: 703  PVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKAD- 761
                  AF   V D  + ++      EE  +  E +  +  E    +    A V   +D 
Sbjct: 689  AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDT 748

Query: 762  ---PAFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEKKEPKEP---REGGGAIEE 815
               P+   E++   G    +P     +            ++   P EP    E  GA   
Sbjct: 749  ESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTP 808

Query: 816  EAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGE 875
                 +  AP     K      EKE E +   P+ + E++K P    EE+  +  ++E  
Sbjct: 809  PPAPPSPSAPPPVVPK-----EEKEEETAAAPPVEEGEEQKPP--AAEELAVDTGKAEEP 861

Query: 876  RKTKVERDIGEG---NLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEI 932
             K++   +  EG        AA A A  A+KA+       R   +  +   +        
Sbjct: 862  VKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATC 921

Query: 933  KLRHFEELETIMDREREALEYQRQQLLAD-----RQAFHMEQLKYAEMRARQQHFQQMHQ 987
                 +E E     ++  L   R  LL         A   + L   +++ R      +  
Sbjct: 922  SADEVDEAE---GGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVT 978

Query: 988  QQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            +  +PP      ++P PP   A PP  +   + P S  P   GS     S  P+      
Sbjct: 979  KVHEPPREDAAPTKPAPP---APPPPQN---LQPESDAPQQPGSSPRGKSRSPA------ 1026

Query: 1048 GSTAGPQQQQPAGAPQPGAVP---PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104
               A  + ++P   P   A     PG PP    G  PFP    PP  +  A P +  P  
Sbjct: 1027 -PPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSG-LPFP---VPPREVIKASPHAPDPSA 1081

Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLP------PDPTAPSPGTVTPVPP 1150
             + +P                   PG PLP        P  P P T++  PP
Sbjct: 1082 FSYAP-------------------PGHPLPLGLHDTARPVLPRPPTISNPPP 1114



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 26/102 (25%), Positives = 37/102 (36%), Gaps = 3/102 (2%)

Query: 305 PSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTK 364
           PSP  EA K   + GP  P T    G          +D+  P+      E T   T    
Sbjct: 752 PSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPA 811

Query: 365 KDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQ 406
             S SAP     +   +E+E+E+      +E E       E+
Sbjct: 812 PPSPSAP---PPVVPKEEKEEETAAAPPVEEGEEQKPPAAEE 850


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 90/368 (24%), Positives = 136/368 (36%), Gaps = 46/368 (12%)

Query: 820  KTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTK 879
            K +  P K+E          ES  S+  P+  P +E  P    EE   E  E +   K +
Sbjct: 324  KDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLK-Q 382

Query: 880  VERDIGEGNLSTAAAAALAAAAVKAKHLAAVEE-RKIKSLVALLVETQMKKLEIKLRHFE 938
            ++                    +  KH    +  ++ + ++      Q   ++++LRH+E
Sbjct: 383  LQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYE 442

Query: 939  ELETIMDREREALEYQRQQLLADRQAF---HMEQLKYAE---------MRARQQH----- 981
              +       +  E++R+  L + Q     H +QL+  E         M+A Q +     
Sbjct: 443  MQQQQFQHLYQ--EWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKV 500

Query: 982  --FQQMHQQ----QQQPPPALPPGSQPIP-PTGAAG--PPAVHGLAVAPA--SVVPAPAG 1030
              FQ M  Q       PPP +P    P P PT      PP++    + PA  + VP P  
Sbjct: 501  NSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPP-- 558

Query: 1031 SGAPPGSLGPS--EQIGQAG-----STAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFP 1083
             G PP  + PS    +   G     S+AGP    P  +      PP +PPP     +P P
Sbjct: 559  -GMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPP 617

Query: 1084 NQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPT-APSP 1142
                PP       PG   PGV    P  + A     +P AS       P  P P   P+P
Sbjct: 618  VMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAP---VPPASSSQSSQVPEKPRPALLPTP 674

Query: 1143 GTVTPVPP 1150
             +    PP
Sbjct: 675  VSFGSAPP 682



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 63/217 (29%), Positives = 81/217 (37%), Gaps = 60/217 (27%)

Query: 977  ARQQHFQQMHQQQQQ---------PPPALPP--------GSQPIPPTGAAGPPA------ 1013
            A+ Q  QQMHQ+Q Q         PPP  PP        G    PP     PP       
Sbjct: 59   AQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQ 118

Query: 1014 ---------VHGLAVAPASVVP-----APAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPA 1059
                     +H     P  +VP      P     PPGS  P  Q     S   P Q  P+
Sbjct: 119  KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQ-----SYMPPPQPPPS 173

Query: 1060 GAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNL 1119
              P P +  P +PP     PSP    Q+PPS    A P   +   ++ S + ++  Q + 
Sbjct: 174  YYP-PTSSQPYLPPA---QPSP---SQSPPSQSYLA-PTPSYSSSSSSSQSYLSHSQ-SY 224

Query: 1120 LPSASPLPDPGTP--------LPPDPTAPSPGTVTPV 1148
            LPS+   P   +          PP P+AP PG  T V
Sbjct: 225  LPSSQASPSRPSQGHSKSQLLAPPPPSAP-PGNKTTV 260



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 51/183 (27%), Positives = 66/183 (36%), Gaps = 25/183 (13%)

Query: 978  RQQHFQQMHQQQQQPPPAL-------PPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAG 1030
            +QQ+  QM   Q+  PP L       PP S P+PP G+  PP+   +        P P  
Sbjct: 120  QQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPP-GSYMPPSQSYMP------PPQPPP 172

Query: 1031 SGAPPGSLGPSEQIGQ-AGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP 1089
            S  PP S  P     Q + S + P Q   A  P   +          H  S  P+ Q  P
Sbjct: 173  SYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASP 232

Query: 1090 SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLL-----PSASPLPDPGTPLPPDPTAPSPGT 1144
            S      P  GH      +P   +A  GN       P  S   +  T        P P T
Sbjct: 233  SR-----PSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPST 287

Query: 1145 VTP 1147
            +TP
Sbjct: 288  MTP 290



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 47/173 (27%), Positives = 63/173 (36%), Gaps = 28/173 (16%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051
            PPP +PP      P   A P A  G   + ++   AP+ SG          Q+ Q     
Sbjct: 15   PPPPVPP------PPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68

Query: 1052 GPQQQ---QPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV---- 1104
              Q Q   QP   P P   PP V P G +G      Q  PP M P   P   +       
Sbjct: 69   QKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDW----QPPPPPMPPPPGPALSYQKQQQYK 124

Query: 1105 ------AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPP 1151
                      P  +  ++    P + P+P PG+ +PP  +   P    P PPP
Sbjct: 125  HQMLHHQRDGPPGLVPMELESPPESPPVP-PGSYMPPSQSYMPP----PQPPP 172



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 39/141 (27%), Positives = 53/141 (37%), Gaps = 28/141 (19%)

Query: 1030 GSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPP-GVPPPGPHGPSPFPNQQTP 1088
            G   PPGS  P   +G+   +       PA +  P   PP  +PPP P  P P P    P
Sbjct: 1504 GMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPP----P 1559

Query: 1089 PSMMP----------------GAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTP 1132
            P + P                G    +   G+ ++  +  AA+     PSA  LP P   
Sbjct: 1560 PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAI-----PSAPVLPPPPVH 1614

Query: 1133 LPPDPTAPSPGTVTPV--PPP 1151
                P  P P  + P+  PPP
Sbjct: 1615 SSIPPPGPVPMGMPPMSKPPP 1635



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 50/211 (23%), Positives = 72/211 (34%), Gaps = 50/211 (23%)

Query: 984  QMHQQQQQPPPAL-PPGSQ-----PIPPTGAAGPPAVHGLAVAPA--------------- 1022
            Q +    QPPP+  PP S      P  P+ +  PP+   LA  P+               
Sbjct: 162  QSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHS 221

Query: 1023 --------------------SVVPAPAGSGAPPGSLGPSEQ--IGQAGSTAGPQQQQPAG 1060
                                S + AP    APPG+    +Q  +         +QQQ A 
Sbjct: 222  QSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAP 281

Query: 1061 APQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLL 1120
             P P  + P       +       QQ     +PG   G   P VA  +P  V   +   +
Sbjct: 282  EPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKG---PVVAKDTPEPVK--EEVTV 336

Query: 1121 PSASPLPDPGTPLPPDPTAPSPGTVTPVPPP 1151
            P+ S +P+  +P   +P  P P    P P P
Sbjct: 337  PATSQVPE--SPSSEEPPLPPPNEEVPPPLP 365



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 51/232 (21%), Positives = 84/232 (36%), Gaps = 42/232 (18%)

Query: 931  EIKLRHFEELETIMDREREALEYQRQQLLADRQAFHM--EQLKYAEMRARQQHFQQMHQQ 988
            EI L+  +EL+ + + ++E L+  +      + A H+  ++ +     +R   +      
Sbjct: 1454 EIILKAAQELKMLRE-QKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSY 1512

Query: 989  QQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAG 1048
            +  PP   PPGS   P    + PPA   +   P +  P P     PP  L P   + +  
Sbjct: 1513 RPPPPMGKPPGSIVRP----SAPPARSSV---PVTRPPVPIPPPPPPPPLPPPPPVIKPQ 1565

Query: 1049 STAGPQQQ------------------------QPAGAPQPGAVPP-----GVPPPGPHGP 1079
            ++A  Q++                        + A  P    +PP      +PPPGP  P
Sbjct: 1566 TSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGP-VP 1624

Query: 1080 SPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGT 1131
               P    PP +      G G      +   I    +  L P   PLP+  T
Sbjct: 1625 MGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRP--DPLPERST 1674



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 29/84 (34%)

Query: 1069 PGV-PPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLP 1127
            PG+ PPPG + P P      P    PG++     P      PA           S+ P+ 
Sbjct: 1503 PGMYPPPGSYRPPP------PMGKPPGSIVRPSAP------PA----------RSSVPVT 1540

Query: 1128 DPGTPLPPDPTAPSPGTVTPVPPP 1151
             P  P+PP P  P      P+PPP
Sbjct: 1541 RPPVPIPPPPPPP------PLPPP 1558



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 9/80 (11%)

Query: 1079 PSPF-PNQQTPP---SMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLP 1134
            P PF P  Q PP   +M P  +P S  P V    PA+ A V    +P     P   T +P
Sbjct: 517  PPPFVPYSQMPPPLPTMPPPVLPPSLPPPV--MPPALPATVPPPGMPPPVMPPSLPTSVP 574

Query: 1135 PDPTAPSPGTVTP---VPPP 1151
            P    PS  +  P   +PPP
Sbjct: 575  PPGMPPSLSSAGPPPVLPPP 594


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 59/168 (35%), Positives = 69/168 (41%), Gaps = 18/168 (10%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAV----APASVVPAPAGSG--APPGSLGPSEQI 1044
            Q PP+ PP S P+ P     P A + LAV    AP S  P+P      +PP S   S   
Sbjct: 406  QAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP-- 462

Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104
                S   P Q  P+ A  P  VPP  P   P  PS  P  Q PP   P A P       
Sbjct: 463  ----SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---PLAAPPLQLAKP 515

Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152
              Q+P  +A      LPS  P   PG   P  P+A  P +    PPPQ
Sbjct: 516  PPQAPPALATPPLQALPS-PPASFPG-QAPFSPSASLPMSPLATPPPQ 561



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 57/188 (30%), Positives = 70/188 (37%), Gaps = 25/188 (13%)

Query: 989  QQQPPPALP--PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPG----SLG-PS 1041
            Q Q PP LP  P S  +    A   P       AP S+   P+    PP     SLG P+
Sbjct: 314  QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 373

Query: 1042 EQIGQA---GSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAV-- 1096
             Q   +        P    P  AP   A+PP   PP P    P     TP    P A+  
Sbjct: 374  LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433

Query: 1097 -----PGSGHPGVAAQSPAIVAAVQGNLLPSASP-------LPDPGTPLPPDPTAPSPGT 1144
                 P S  P    Q+P    A    + PSA+P       L  P   +PP P A  P +
Sbjct: 434  HLLQAPFSPPPSPPVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492

Query: 1145 VTPVPPPQ 1152
             +  PPPQ
Sbjct: 493  PSATPPPQ 500



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 53/179 (29%), Positives = 65/179 (36%), Gaps = 37/179 (20%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSG-----------APPGSLGPSE 1042
            P  PP S P+ P+      A   LA  P  V P+P  S            APP    P  
Sbjct: 451  PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510

Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP 1102
            Q+ +      P Q  PA A  P    P  P   P G +PF    + P M P A P     
Sbjct: 511  QLAKP-----PPQAPPALATPPLQALPSPPASFP-GQAPFSPSASLP-MSPLATP----- 558

Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGT----------VTPVPPP 1151
                Q+P ++AA    + P  SP   P    P  P  P P T          + P PPP
Sbjct: 559  --PPQAPPVLAAPLLQVPP--SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 61/221 (27%), Positives = 74/221 (33%), Gaps = 60/221 (27%)

Query: 988  QQQQPPPALPPG-------SQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040
            Q  +PPP  PP        + P PP    G       A  P S +  P    APP    P
Sbjct: 511  QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ-APPVLAAP 569

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPG------------AVPPGVPPPGPHGPSP------F 1082
              Q+  +   A P  Q P   P PG            A+ PG PPP    PS        
Sbjct: 570  LLQVPPS-PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 628

Query: 1083 PNQQTPPSMMPGAVPG--SGHPGVAAQSP---AIVAAVQGNLLPSASPLPD------PGT 1131
                +  +  P  + G  SG  G AA SP   A +AA       S  P P       PG 
Sbjct: 629  AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW-SRGPAPPLAFRGAPGA 687

Query: 1132 PLP---------------------PDPTAPSPGTVTPVPPP 1151
            PLP                     P+   P+PG + P P P
Sbjct: 688  PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 56/199 (28%), Positives = 67/199 (33%), Gaps = 42/199 (21%)

Query: 989  QQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAG 1048
            Q  PP A PP     PP  A  PPA   LA  P   +P+P  S        PS  +  + 
Sbjct: 500  QAPPPLAAPPLQLAKPPPQA--PPA---LATPPLQALPSPPASFPGQAPFSPSASLPMSP 554

Query: 1049 STAGPQQQQPAGA-------PQPGAVP----PGVPP-PGP----HGP----SPFPNQQTP 1088
                P Q  P  A       P P A P    P  PP PGP     GP    +  P    P
Sbjct: 555  LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614

Query: 1089 PSMMPGAVPG----SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGT------------- 1131
            PS  P +       +GH   A  +P  +          A+  P P               
Sbjct: 615  PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674

Query: 1132 PLPPDPTAPSPGTVTPVPP 1150
            P PP     +PG   P PP
Sbjct: 675  PAPPLAFRGAPGAPLPWPP 693



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 49/163 (30%), Positives = 61/163 (37%), Gaps = 23/163 (14%)

Query: 1005 PTGAAGP--PAVHGL-AVAPASVVPAPAGSGAPPGSLGP--SEQIGQAGSTAGPQQQQPA 1059
            P   A P  P   GL A+ P  V P P    AP  +LGP  S  +     +A  Q Q P 
Sbjct: 263  PRAPAHPSQPKPKGLQALRPPQVTP-PRKDAAP--ALGPLSSSPLATPSPSAALQSQAPP 319

Query: 1060 GAPQPG---------AVPPGVPPPGPHGPSPFPNQQTPPSMMPG-AVPGSGHPGVAAQSP 1109
              P            A P  + PP P  P       +PP+  P  A    G P + A   
Sbjct: 320  TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 379

Query: 1110 AIVAAVQGNLLPSASPLPD--PGTPLPPDPTAPSPGTVTPVPP 1150
             + +     L P A+P P   P   LPP    PSP    P+ P
Sbjct: 380  FLPSP---PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 419



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 41/165 (24%), Positives = 57/165 (34%), Gaps = 26/165 (15%)

Query: 1009 AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS--EQIGQAGSTAGPQQQQPAGAPQPGA 1066
            AG  A    A AP  + P P GS  PP  + P+    +G AG+       + AG      
Sbjct: 10   AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69

Query: 1067 VPPGVPPPGP--------HGPS-------------PFPNQQTPPSMMPGAVPGSGHPGVA 1105
            +P   P  GP          P+             P  N    P   PG   G+  PG  
Sbjct: 70   IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129

Query: 1106 AQSPAIVAAVQGNLLPSASPLPDP---GTPLPPDPTAPSPGTVTP 1147
             Q    ++A +      A+  P           D + P+PGT +P
Sbjct: 130  GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174



 Score = 34.7 bits (78), Expect = 0.54
 Identities = 42/167 (25%), Positives = 58/167 (34%), Gaps = 38/167 (22%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAV--------APASVVPAPAGSGAPPGSLGPSEQIG 1045
            P  PP   P P T  +GP     LA         +P+S +  P  +G    +    E++ 
Sbjct: 586  PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643

Query: 1046 ------QAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS 1099
                  + G+ A P       A  P A   G  PP     +P      PP+  PG+  G 
Sbjct: 644  GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 703

Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP--DPTAPSPGT 1144
                        +   +G         P+  TP P   DP  PSPGT
Sbjct: 704  ----------CTIYETEG---------PESATPAPGALDP-GPSPGT 730


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 59/168 (35%), Positives = 69/168 (41%), Gaps = 18/168 (10%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAV----APASVVPAPAGSG--APPGSLGPSEQI 1044
            Q PP+ PP S P+ P     P A + LAV    AP S  P+P      +PP S   S   
Sbjct: 367  QAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP-- 423

Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104
                S   P Q  P+ A  P  VPP  P   P  PS  P  Q PP   P A P       
Sbjct: 424  ----SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---PLAAPPLQLAKP 476

Query: 1105 AAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ 1152
              Q+P  +A      LPS  P   PG   P  P+A  P +    PPPQ
Sbjct: 477  PPQAPPALATPPLQALPS-PPASFPG-QAPFSPSASLPMSPLATPPPQ 522



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 55/197 (27%), Positives = 70/197 (35%), Gaps = 36/197 (18%)

Query: 988  QQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGA-----PPGSLGPSE 1042
            Q  +PP   PP     P   A GP +   LA    S  P+P+   +      P +  PS+
Sbjct: 269  QALRPPQVTPPRKDAAP---ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325

Query: 1043 QIGQAGSTA-------------GPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP 1089
                 GS                P    P  AP   A+PP   PP P    P     TP 
Sbjct: 326  ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385

Query: 1090 SMMPGAV-------PGSGHPGVAAQSPAIVAAVQGNLLPSASP-------LPDPGTPLPP 1135
               P A+       P S  P    Q+P    A    + PSA+P       L  P   +PP
Sbjct: 386  PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVPP 444

Query: 1136 DPTAPSPGTVTPVPPPQ 1152
             P A  P + +  PPPQ
Sbjct: 445  SPPASPPMSPSATPPPQ 461



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 53/179 (29%), Positives = 65/179 (36%), Gaps = 37/179 (20%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSG-----------APPGSLGPSE 1042
            P  PP S P+ P+      A   LA  P  V P+P  S            APP    P  
Sbjct: 412  PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 471

Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP 1102
            Q+ +      P Q  PA A  P    P  P   P G +PF    + P M P A P     
Sbjct: 472  QLAKP-----PPQAPPALATPPLQALPSPPASFP-GQAPFSPSASLP-MSPLATP----- 519

Query: 1103 GVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGT----------VTPVPPP 1151
                Q+P ++AA    + P  SP   P    P  P  P P T          + P PPP
Sbjct: 520  --PPQAPPVLAAPLLQVPP--SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 61/221 (27%), Positives = 73/221 (33%), Gaps = 60/221 (27%)

Query: 988  QQQQPPPALPPG-------SQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040
            Q  +PPP  PP        + P PP    G       A  P S +  P    APP    P
Sbjct: 472  QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ-APPVLAAP 530

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPG------------AVPPGVPPPGPHGPS------PF 1082
              Q+      A P  Q P   P PG            A+ PG PPP    PS        
Sbjct: 531  LLQV-PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 589

Query: 1083 PNQQTPPSMMPGAVPG--SGHPGVAAQSP---AIVAAVQGNLLPSASPLPD------PGT 1131
                +  +  P  + G  SG  G AA SP   A +AA       S  P P       PG 
Sbjct: 590  AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW-SRGPAPPLAFRGAPGA 648

Query: 1132 PLP---------------------PDPTAPSPGTVTPVPPP 1151
            PLP                     P+   P+PG + P P P
Sbjct: 649  PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 56/199 (28%), Positives = 67/199 (33%), Gaps = 42/199 (21%)

Query: 989  QQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAG 1048
            Q  PP A PP     PP  A  PPA   LA  P   +P+P  S        PS  +  + 
Sbjct: 461  QAPPPLAAPPLQLAKPPPQA--PPA---LATPPLQALPSPPASFPGQAPFSPSASLPMSP 515

Query: 1049 STAGPQQQQPAGA-------PQPGAVP----PGVPP-PGP----HGP----SPFPNQQTP 1088
                P Q  P  A       P P A P    P  PP PGP     GP    +  P    P
Sbjct: 516  LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575

Query: 1089 PSMMPGAVPG----SGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGT------------- 1131
            PS  P +       +GH   A  +P  +          A+  P P               
Sbjct: 576  PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635

Query: 1132 PLPPDPTAPSPGTVTPVPP 1150
            P PP     +PG   P PP
Sbjct: 636  PAPPLAFRGAPGAPLPWPP 654



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 41/156 (26%), Positives = 56/156 (35%), Gaps = 17/156 (10%)

Query: 1009 AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS--EQIGQAGSTAGPQQQQPAGAPQPGA 1066
            AG  A    A AP  + P P GS  PP  + P+    +G AG+       + AG      
Sbjct: 10   AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69

Query: 1067 VPPGVPPPGPHGPS------------PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAA 1114
            +P   P  GP   S            P  N    P   PG   G+  PG   Q    ++A
Sbjct: 70   IPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129

Query: 1115 VQGNLLPSASPLPDP---GTPLPPDPTAPSPGTVTP 1147
             +      A+  P           D + P+PGT +P
Sbjct: 130  EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 165



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 47/165 (28%), Positives = 62/165 (37%), Gaps = 32/165 (19%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051
            P PA  P ++P PPT   GP      A   ++  P+PA    P               +A
Sbjct: 181  PRPA--PSARPRPPT--EGPRKSVSSASEHSTTEPSPAARRRP---------------SA 221

Query: 1052 GPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP-GVAAQSPA 1110
            G   Q+PA      +  P +  P   GPS     + P      A P    P G+ A  P 
Sbjct: 222  GGGLQRPASRSLSSSATP-LSSPARSGPSARGTPRAP------AHPSQPKPKGLQALRPP 274

Query: 1111 IVAAVQGNLLP-----SASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150
             V   + +  P     S+SPL  P    PP P+AP      P PP
Sbjct: 275  QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPP 319



 Score = 34.7 bits (78), Expect = 0.54
 Identities = 42/167 (25%), Positives = 58/167 (34%), Gaps = 38/167 (22%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAV--------APASVVPAPAGSGAPPGSLGPSEQIG 1045
            P  PP   P P T  +GP     LA         +P+S +  P  +G    +    E++ 
Sbjct: 547  PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 604

Query: 1046 ------QAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS 1099
                  + G+ A P       A  P A   G  PP     +P      PP+  PG+  G 
Sbjct: 605  GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 664

Query: 1100 GHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP--DPTAPSPGT 1144
                        +   +G         P+  TP P   DP  PSPGT
Sbjct: 665  ----------CTIYETEG---------PESATPAPGALDP-GPSPGT 691


>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
          Length = 1488

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 59/197 (29%), Positives = 74/197 (37%), Gaps = 38/197 (19%)

Query: 979  QQHFQQMHQQQQQ-----PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGA 1033
            Q   Q +H Q  Q     PPP LPP    +PP     PP          S+ P PA   A
Sbjct: 1261 QSKLQALHAQYCQGPGPAPPPYLPPQQPSLPPPPQQPPPLPQ-----LGSIPPPPA--SA 1313

Query: 1034 PPGSLGPSEQIGQAGSTAGPQQQ---QPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPS 1090
            PP  +GP       G   GPQ     +P  AP+ GA   G P   PHG  P      P S
Sbjct: 1314 PP--VGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGA--GGHPQFAPHGRHPL---HQPTS 1366

Query: 1091 MMPGAVPGSGHPGVAAQSPA-IVAAVQGNLLPSASPLPDPG---------------TPLP 1134
             +P   P   HP    Q P   + +    ++P+A     PG               +PL 
Sbjct: 1367 PLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLS 1426

Query: 1135 PDPTAPSPGTVTPVPPP 1151
            P    P   +  P+PPP
Sbjct: 1427 PHSPIPPHPSYPPLPPP 1443



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 40/129 (31%), Positives = 51/129 (39%), Gaps = 18/129 (13%)

Query: 981  HFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040
            H +    Q   P P   P  Q  PP    GP   H +      ++PA AG+   PGS  P
Sbjct: 1356 HGRHPLHQPTSPLPLYSPAPQH-PPAHKQGPK--HFIFSHHPQMMPA-AGAAGGPGSRPP 1411

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVP----PGVPPPGPHGPSPFPNQQTPPSMMPGAV 1096
                   GS + P   Q   +P     P    P +PPP PH P    +   PP+   G +
Sbjct: 1412 G------GSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTP----HSPLPPTSPHGPL 1461

Query: 1097 PGSGHPGVA 1105
              SG PG A
Sbjct: 1462 HASGPPGTA 1470


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
            sapiens]
          Length = 406

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 91/379 (24%), Positives = 135/379 (35%), Gaps = 49/379 (12%)

Query: 795  QATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEK 854
            +  DEK         GG  EE  + K     + +   G EG    + +  +G    +PE+
Sbjct: 25   EVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQ 84

Query: 855  EKE------PKEGQEE--VLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVKAKH 906
            ++E      P++ QEE  +L+   E E   +T VE         TA          K + 
Sbjct: 85   QQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGP--QPPERKRRR 142

Query: 907  LAAVEERKIKSLVALLVETQ------MKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
              A  + +++ L     E+Q       ++L  +L   E+   +  + R A   + Q++L 
Sbjct: 143  RTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLM 202

Query: 961  DRQAFHMEQLKYAEMRARQQHFQQ--------MHQQQQQP-PPALPPGSQPIPPTGAAGP 1011
             R     +     +M     ++          +H   Q P PP LP    P  P     P
Sbjct: 203  LRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMP 262

Query: 1012 PAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV 1071
            P      + P  + P P GS   P   GP            P    P  AP P   P   
Sbjct: 263  PRPPIAPMPP--MAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAP 320

Query: 1072 PPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGT 1131
             PPGP      P  + PP      VP    P +A   P           P  +PLP PG 
Sbjct: 321  VPPGP------PMARVPPGPPMARVPPG--PPMAPLPPG----------PPMAPLP-PGP 361

Query: 1132 PLPPDPTAPSPGTVTPVPP 1150
            P+ P P  P    + P+PP
Sbjct: 362  PMAPLPPGP---PMAPLPP 377


>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
          Length = 753

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 60/180 (33%), Positives = 70/180 (38%), Gaps = 46/180 (25%)

Query: 998  PGSQPIPPTGAAGPP-AVHGLAVAPASV-VPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQ 1055
            P S  +PPT  +GPP A   L+  P +  VPAPA   APP +LGP          A P  
Sbjct: 314  PQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPA---APPSALGPK---------ASPAP 361

Query: 1056 QQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPG------------ 1103
               +G P P A    V PP P GPS    Q  PPS+ P    G G  G            
Sbjct: 362  SHNSGTPAPYA--QAVAPPAPSGPS--TTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAG 417

Query: 1104 --------------VAAQSPAIVA--AVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTP 1147
                          V A SPA VA  +  GN   S +  P  G   PP  T+  P    P
Sbjct: 418  GGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAP 477



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 50/191 (26%), Positives = 70/191 (36%), Gaps = 45/191 (23%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPA-------------SVVPAPAGSGAPPGSL 1038
            PP AL P + P P   + G PA +  AVAP              SV P+  G G   G  
Sbjct: 349  PPSALGPKASPAPSHNS-GTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGG 407

Query: 1039 GPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV----------------PPPGPHGPSPF 1082
              S     AG  AG Q    + +      P  V                PP GPH P P 
Sbjct: 408  SSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPS 467

Query: 1083 PNQQ---TPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTA 1139
             +++     P+   G  PGSG+    +  P+++  +         P+  P +P P    A
Sbjct: 468  TSKEPSAAAPTGAGGVAPGSGN---NSGGPSLLVPL---------PVNPPSSPTPSFSDA 515

Query: 1140 PSPGTVTPVPP 1150
             + G +   PP
Sbjct: 516  KAAGALLNGPP 526



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 58/220 (26%), Positives = 78/220 (35%), Gaps = 40/220 (18%)

Query: 938  EELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALP 997
            +++E  +D  ++    + + L  D     + Q   A       H +     Q    P   
Sbjct: 205  DDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTST 264

Query: 998  PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQ 1057
              S PIPP+              PA+     +      G    SE + Q+ +  G +   
Sbjct: 265  TSSSPIPPS--------------PANCTTENSEDDKKRGRSTDSE-VSQSPAKNGSKPVH 309

Query: 1058 PAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQG 1117
                PQ     P VPP  P GP P  +     S  PG    +G P  AA   A       
Sbjct: 310  SNQHPQS----PAVPPTYPSGPPPAASAL---STTPG---NNGVPAPAAPPSA------- 352

Query: 1118 NLLPSASPLP--DPGTPLP----PDPTAPS-PGTVTPVPP 1150
             L P ASP P  + GTP P      P APS P T  P PP
Sbjct: 353  -LGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPP 391


>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
          Length = 756

 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 57/169 (33%), Positives = 68/169 (40%), Gaps = 24/169 (14%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP----GSLG--PSEQIGQ 1046
            PP    G+ P+PPTG +G P V     + A  VP    SGAPP    G  G  P    G 
Sbjct: 586  PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 645

Query: 1047 AGSTAGPQQQQPAGAPQP---GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGA--VPGSGH 1101
            +G+   P        P P    +  P VPP G  GP P      PP+   GA  VP +G 
Sbjct: 646  SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPP-----VPPTGDSGAPPVPPTGD 700

Query: 1102 PGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150
             G    +P +         P   P  D G P P  PT  S     PVPP
Sbjct: 701  SG----APPVTPTGDSETAP-VPPTGDSGAP-PVPPTGDS--EAAPVPP 741



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 54/160 (33%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052
            PP     + P+PPTG +G P V     + A  VP    SGAPP  + P+   G +G+   
Sbjct: 575  PPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPP--VPPT---GDSGAPPV 629

Query: 1053 PQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGA--VPGSGHPGVAAQSPA 1110
            P        P P     G PP  P G S  P    PP+   GA  VP +G  G     P 
Sbjct: 630  PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAP--PVPPTGDSGAPPVPPTGDAG-----PP 682

Query: 1111 IVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPP 1150
             V     +  P   P  D G P P  PT  S     PVPP
Sbjct: 683  PVPPTGDSGAPPVPPTGDSGAP-PVTPTGDS--ETAPVPP 719



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 14/105 (13%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052
            PP    G+ P+PPTG AGPP V     + A  VP    SGAPP             +  G
Sbjct: 663  PPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPP------------VTPTG 710

Query: 1053 PQQQQPAGAPQPGAVPPGVPPPGPHGPSPF-PNQQTPPSMMPGAV 1096
              +  P         PP VPP G    +P  P   +  + MP  +
Sbjct: 711  DSETAPVPPTGDSGAPP-VPPTGDSEAAPVPPTDDSKEAQMPAVI 754


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 67/250 (26%), Positives = 97/250 (38%), Gaps = 25/250 (10%)

Query: 923  VETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHF 982
            V  Q ++L+ + +  + L  +  + ++ ++ Q+QQL    Q     QL+  + + +QQ  
Sbjct: 203  VVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL----QRIAQLQLQQQQQQQQQQQQ 258

Query: 983  QQMHQQQQQPPPALPPGSQPIPPTGAAGPPAV----HGLAVAPASVVPAPAGSGAPPGSL 1038
            QQ    Q QPP   PP  QP PP   A P  +    H     P      P  +   P  L
Sbjct: 259  QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQL 318

Query: 1039 GPSEQ----IGQAGSTAGPQ-QQQP----AGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP 1089
             P  Q    + QA +  G     QP      AP     PP V P      +     Q   
Sbjct: 319  PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPP-VQPQVQQQQTAVQTAQAAQ 377

Query: 1090 SMMPGA-VPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPT------APSP 1142
             + PG  V  S  P +++ SP        ++ P   P P PG P     +      APSP
Sbjct: 378  MVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSP 437

Query: 1143 GTVTPVPPPQ 1152
             +  P P PQ
Sbjct: 438  SSFLPSPSPQ 447



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 78/290 (26%), Positives = 111/290 (38%), Gaps = 47/290 (16%)

Query: 900  AAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLL 959
            +A++ +  A V++++      L  + Q ++  IKL H +  + I  ++++     + QL 
Sbjct: 194  SAMQQQFQAVVQQQQ-----QLQQQQQQQQHLIKLHH-QNQQQIQQQQQQLQRIAQLQLQ 247

Query: 960  ADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPP--ALPPGSQPI-------PPTGAAG 1010
              +Q    +Q +  +    Q   QQ   QQ QPPP  ALP   Q +       PP     
Sbjct: 248  QQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQ 307

Query: 1011 PPAVHGL------------AVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQP 1058
            PP                  V+ A  +P       PP     +  + Q      PQ QQ 
Sbjct: 308  PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ-PPVQPQVQQQ 366

Query: 1059 AGAPQPG----AVPPGVPP-----PGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSP 1109
              A Q       V PGV       P    PSP    QTP SM P   P S  PG  +  P
Sbjct: 367  QTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP-SPQPGQPSSQP 425

Query: 1110 -----AIVAAVQGNLLPSASPLPDPG---TPLPPDPTAPSPGTV-TPVPP 1150
                 +  A    + LPS SP P         P + + PSPG + TPV P
Sbjct: 426  NSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNP 475



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 8/68 (11%)

Query: 924 ETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQ 983
           +TQ++  ++ L+  ++ +    +++ AL+ Q+QQ          +Q   A+  A QQ FQ
Sbjct: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQ--------QQQQQFQAQQSAMQQQFQ 201

Query: 984 QMHQQQQQ 991
            + QQQQQ
Sbjct: 202 AVVQQQQQ 209


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.129    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,370,647
Number of Sequences: 37866
Number of extensions: 3644058
Number of successful extensions: 66353
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 794
Number of HSP's successfully gapped in prelim test: 2551
Number of HSP's that attempted gapping in prelim test: 22069
Number of HSP's gapped (non-prelim): 23216
length of query: 1152
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1039
effective length of database: 13,968,660
effective search space: 14513437740
effective search space used: 14513437740
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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