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Search of human proteins with 194353976
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194353976 transcription factor AP-2 epsilon (activating
enhancer binding protein 2 epsilon) [Homo sapiens]
(442 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194353976 transcription factor AP-2 epsilon (activating enhan... 889 0.0
gi|118582289 transcription factor AP-2 beta [Homo sapiens] 502 e-142
gi|73760407 transcription factor AP-2 alpha isoform b [Homo sapi... 495 e-140
gi|109389358 transcription factor AP-2 alpha isoform c [Homo sap... 481 e-136
gi|4507441 transcription factor AP-2 alpha isoform a [Homo sapiens] 481 e-136
gi|4507445 transcription factor AP-2 gamma [Homo sapiens] 392 e-109
gi|151301211 transcription factor AP-2 beta-like 1 [Homo sapiens] 324 9e-89
gi|197245373 proline rich 22 isoform 1 [Homo sapiens] 51 2e-06
gi|23503299 proline rich 22 isoform 2 [Homo sapiens] 51 2e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 51 2e-06
gi|19263349 Cbp/p300-interacting transactivator, with Glu/Asp-ri... 50 4e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens] 50 5e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 49 9e-06
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho... 48 2e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 47 3e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 47 3e-05
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 46 6e-05
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 46 6e-05
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 46 6e-05
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 46 6e-05
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 46 6e-05
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 45 2e-04
gi|57165375 glutamate receptor, ionotropic, N-methyl D-aspartate... 44 2e-04
gi|57165373 glutamate receptor, ionotropic, N-methyl D-aspartate... 44 2e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 44 4e-04
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 42 9e-04
gi|62953127 polyhomeotic 1-like [Homo sapiens] 42 9e-04
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 42 9e-04
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens] 42 9e-04
gi|208431824 forkhead box I3 [Homo sapiens] 42 0.001
>gi|194353976 transcription factor AP-2 epsilon (activating enhancer
binding protein 2 epsilon) [Homo sapiens]
Length = 442
Score = 889 bits (2297), Expect = 0.0
Identities = 442/442 (100%), Positives = 442/442 (100%)
Query: 1 MLVHTYSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYP 60
MLVHTYSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYP
Sbjct: 1 MLVHTYSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYP 60
Query: 61 QPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPP 120
QPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPP
Sbjct: 61 QPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPP 120
Query: 121 ARALGLDPRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLL 180
ARALGLDPRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLL
Sbjct: 121 ARALGLDPRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLL 180
Query: 181 DQSVIKKVPIPSKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLSSTSKYKVTVGE 240
DQSVIKKVPIPSKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLSSTSKYKVTVGE
Sbjct: 181 DQSVIKKVPIPSKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLSSTSKYKVTVGE 240
Query: 241 VQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLV 300
VQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLV
Sbjct: 241 VQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLV 300
Query: 301 EGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMA 360
EGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMA
Sbjct: 301 EGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMA 360
Query: 361 QDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMF 420
QDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMF
Sbjct: 361 QDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMF 420
Query: 421 LSSVGSGHGETKASEKDAKHRK 442
LSSVGSGHGETKASEKDAKHRK
Sbjct: 421 LSSVGSGHGETKASEKDAKHRK 442
>gi|118582289 transcription factor AP-2 beta [Homo sapiens]
Length = 460
Score = 502 bits (1293), Expect = e-142
Identities = 285/451 (63%), Positives = 331/451 (73%), Gaps = 36/451 (7%)
Query: 10 ERPDGLGAAAGG-ARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQ 68
+R DG+ + + ++L S+ Q Y APPL HTP++ +FQPPYFPPPY PLPY Q
Sbjct: 28 DRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSS----DFQPPYFPPPYQ--PLPYHQ 81
Query: 69 APDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARAL---- 124
+ D + H+ DPY L PL QPQ Q W R E LL P AL
Sbjct: 82 SQDP---YSHV-NDPYS-LNPLHQPQ--QHPWGQ-RQRQEVGSEAGSLLPQPRAALPQLS 133
Query: 125 GLDPRRDYATA--VPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEP---GMSL 179
GLDPRRDY + LLH G L L GL PG+ED+Q++++ GM+L
Sbjct: 134 GLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGH-PGMEDVQSVEDANNSGMNL 192
Query: 180 LDQSVIKKVPIPSKASSLSALSLAKDSLVGGIT-NPGEVFCSVPGRLSLLSSTSKYKVTV 238
LDQSVIKKVP+P K S+++L + KD +GG++ N GEVFCSVPGRLSLLSSTSKYKVTV
Sbjct: 193 LDQSVIKKVPVPPK--SVTSLMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTV 250
Query: 239 GEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTS 298
GEVQRRLSPPECLNASLLGGVLRRAKSKNGGR LRERLEKIGLNLPAGRRKAANVTLLTS
Sbjct: 251 GEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTS 310
Query: 299 LVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADL 358
LVEGEAVHLARDFGY+CETEFPAKA +EYL RQH DP +LHSRK+MLLA KQ+CKEF DL
Sbjct: 311 LVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDL 370
Query: 359 MAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDK 418
+AQDR+P+GNSRP+ ILEPG+QSCLTHFSLITHGFG PAICAALTA QNYL E+LKG+DK
Sbjct: 371 LAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDK 430
Query: 419 MFLSSV-------GSGHGETKASEKDAKHRK 442
MFL++ G G G +K +K+ KHRK
Sbjct: 431 MFLNNTTTNRHTSGEGPG-SKTGDKEEKHRK 460
>gi|73760407 transcription factor AP-2 alpha isoform b [Homo
sapiens]
Length = 431
Score = 495 bits (1274), Expect = e-140
Identities = 281/455 (61%), Positives = 333/455 (73%), Gaps = 37/455 (8%)
Query: 1 MLVHTYSAMERPDGLGAAAGGARLSSLP---QAAYGPAPPLCHTPAATAAAEFQPPYFPP 57
MLVH++SAM+R DG + G ARL L Q+ Y APPL HTP A +FQPPYFPP
Sbjct: 1 MLVHSFSAMDRHDG--TSNGTARLPQLGTVGQSPYTSAPPLSHTPNA----DFQPPYFPP 54
Query: 58 PYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPL-AQPQPPQAAWAAPRAAARAHEEPPGL 116
PY QP P Q P + H+ DPY L PL AQPQP W R + + GL
Sbjct: 55 PY-QPIYPQSQDP-----YSHV-NDPYS-LNPLHAQPQPQHPGWPGQRQSQES-----GL 101
Query: 117 LAP----PARALGLDPRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAM 172
L P + GLDPRRDY LLHG + GL D L + L A +E++ +
Sbjct: 102 LHTHRGLPHQLSGLDPRRDYRRHED-LLHGPHALSSGLGD--LSIHSLPHA--IEEVPHV 156
Query: 173 DEPGMSLLDQSVIKKVPIP---SKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLS 229
++PG+++ DQ+VIKK P+ S ++++SA+ + KD+L GG+ NP EVFCSVPGRLSLLS
Sbjct: 157 EDPGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLS 216
Query: 230 STSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRK 289
STSKYKVTV EVQRRLSPPECLNASLLGGVLRRAKSKNGGR LRE+L+KIGLNLPAGRRK
Sbjct: 217 STSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRK 276
Query: 290 AANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAK 349
AANVTLLTSLVEGEAVHLARDFGYVCETEFPAKA AE+L RQH+DP E +RK+MLLA K
Sbjct: 277 AANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATK 336
Query: 350 QICKEFADLMAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYL 409
QICKEF DL+AQDRSPLGNSRP ILEPG+QSCLTHF+LI+HGFG PA+CAA+TA QNYL
Sbjct: 337 QICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYL 396
Query: 410 LESLKGLDKMFLSSVGSGH--GETKASEKDAKHRK 442
E+LK +DKM+LS+ + H K+S+K+ KHRK
Sbjct: 397 TEALKAMDKMYLSNNPNSHTDNNAKSSDKEEKHRK 431
>gi|109389358 transcription factor AP-2 alpha isoform c [Homo
sapiens]
Length = 433
Score = 481 bits (1238), Expect = e-136
Identities = 272/440 (61%), Positives = 321/440 (72%), Gaps = 35/440 (7%)
Query: 16 GAAAGGARLSSLP---QAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDA 72
G + G ARL L Q+ Y APPL HTP A +FQPPYFPPPY QP P Q P
Sbjct: 16 GTSNGTARLPQLGTVGQSPYTSAPPLSHTPNA----DFQPPYFPPPY-QPIYPQSQDP-- 68
Query: 73 AAAFPHLAGDPYGGLAPL-AQPQPPQAAWAAPRAAARAHEEPPGLLAP----PARALGLD 127
+ H+ DPY L PL AQPQP W R + + GLL P + GLD
Sbjct: 69 ---YSHV-NDPYS-LNPLHAQPQPQHPGWPGQRQSQES-----GLLHTHRGLPHQLSGLD 118
Query: 128 PRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIKK 187
PRRDY LLHG + GL D L + L A +E++ +++PG+++ DQ+VIKK
Sbjct: 119 PRRDYRRHED-LLHGPHALSSGLGD--LSIHSLPHA--IEEVPHVEDPGINIPDQTVIKK 173
Query: 188 VPIP---SKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLSSTSKYKVTVGEVQRR 244
P+ S ++++SA+ + KD+L GG+ NP EVFCSVPGRLSLLSSTSKYKVTV EVQRR
Sbjct: 174 GPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRR 233
Query: 245 LSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEA 304
LSPPECLNASLLGGVLRRAKSKNGGR LRE+L+KIGLNLPAGRRKAANVTLLTSLVEGEA
Sbjct: 234 LSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEA 293
Query: 305 VHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRS 364
VHLARDFGYVCETEFPAKA AE+L RQH+DP E +RK+MLLA KQICKEF DL+AQDRS
Sbjct: 294 VHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRS 353
Query: 365 PLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMFLSSV 424
PLGNSRP ILEPG+QSCLTHF+LI+HGFG PA+CAA+TA QNYL E+LK +DKM+LS+
Sbjct: 354 PLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNN 413
Query: 425 GSGH--GETKASEKDAKHRK 442
+ H K+S+K+ KHRK
Sbjct: 414 PNSHTDNNAKSSDKEEKHRK 433
>gi|4507441 transcription factor AP-2 alpha isoform a [Homo sapiens]
Length = 437
Score = 481 bits (1238), Expect = e-136
Identities = 272/440 (61%), Positives = 321/440 (72%), Gaps = 35/440 (7%)
Query: 16 GAAAGGARLSSLP---QAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDA 72
G + G ARL L Q+ Y APPL HTP A +FQPPYFPPPY QP P Q P
Sbjct: 20 GTSNGTARLPQLGTVGQSPYTSAPPLSHTPNA----DFQPPYFPPPY-QPIYPQSQDP-- 72
Query: 73 AAAFPHLAGDPYGGLAPL-AQPQPPQAAWAAPRAAARAHEEPPGLLAP----PARALGLD 127
+ H+ DPY L PL AQPQP W R + + GLL P + GLD
Sbjct: 73 ---YSHV-NDPYS-LNPLHAQPQPQHPGWPGQRQSQES-----GLLHTHRGLPHQLSGLD 122
Query: 128 PRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIKK 187
PRRDY LLHG + GL D L + L A +E++ +++PG+++ DQ+VIKK
Sbjct: 123 PRRDYRRHED-LLHGPHALSSGLGD--LSIHSLPHA--IEEVPHVEDPGINIPDQTVIKK 177
Query: 188 VPIP---SKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLSSTSKYKVTVGEVQRR 244
P+ S ++++SA+ + KD+L GG+ NP EVFCSVPGRLSLLSSTSKYKVTV EVQRR
Sbjct: 178 GPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRR 237
Query: 245 LSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEA 304
LSPPECLNASLLGGVLRRAKSKNGGR LRE+L+KIGLNLPAGRRKAANVTLLTSLVEGEA
Sbjct: 238 LSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEA 297
Query: 305 VHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRS 364
VHLARDFGYVCETEFPAKA AE+L RQH+DP E +RK+MLLA KQICKEF DL+AQDRS
Sbjct: 298 VHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRS 357
Query: 365 PLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMFLSSV 424
PLGNSRP ILEPG+QSCLTHF+LI+HGFG PA+CAA+TA QNYL E+LK +DKM+LS+
Sbjct: 358 PLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNN 417
Query: 425 GSGH--GETKASEKDAKHRK 442
+ H K+S+K+ KHRK
Sbjct: 418 PNSHTDNNAKSSDKEEKHRK 437
>gi|4507445 transcription factor AP-2 gamma [Homo sapiens]
Length = 450
Score = 392 bits (1008), Expect = e-109
Identities = 242/444 (54%), Positives = 295/444 (66%), Gaps = 31/444 (6%)
Query: 16 GAAAGGAR---LSSLPQAAYGPAPPLCHTPAATAAAEFQPP-YFPPPYPQPPLPYGQAPD 71
G++ G R LSS Q Y PAPPL HT AE+QPP YFPPPY Q L Y Q+ D
Sbjct: 21 GSSNGNPRVPHLSSAGQHLYSPAPPLSHT----GVAEYQPPPYFPPPYQQ--LAYSQSAD 74
Query: 72 AAAAFPHLAGDPYGGLAPLAQPQPP---QAAWAAPRAAARA-----HEEPPGLLAPPA-- 121
+ HL + PL QP P Q AW ++ A H P GLL +
Sbjct: 75 P---YSHLGEAYAAAINPLHQPAPTGSQQQAWPGRQSQEGAGLPSHHGRPAGLLPHLSGL 131
Query: 122 RALGLDPRRD-YATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLL 180
A + RRD Y + L H A A GLA+ LGL + ++++Q +D+ + L
Sbjct: 132 EAGAVSARRDAYRRSDLLLPHAHALDAAGLAEN-LGLHDMPHQ--MDEVQNVDDQHLLLH 188
Query: 181 DQSVIKKVPIPSKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLSSTSKYKVTVGE 240
DQ+VI+K PI + L+ L K+ LVG + NP EVFCSVPGRLSLLSSTSKYKVTV E
Sbjct: 189 DQTVIRKGPISMTKNPLN-LPCQKE-LVGAVMNPTEVFCSVPGRLSLLSSTSKYKVTVAE 246
Query: 241 VQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLV 300
VQRRLSPPECLNASLLGGVLRRAKSKNGGR LRE+L+KIGLNLPAGRRKAA+VTLLTSLV
Sbjct: 247 VQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAAHVTLLTSLV 306
Query: 301 EGEAVHLARDFGYVCETEFPAKAAAEYLCRQH-ADPGELHSRKSMLLAAKQICKEFADLM 359
EGEAVHLARDF YVCE EFP+K AEYL R H E+ +RK+MLLAA+Q+CKEF +L+
Sbjct: 307 EGEAVHLARDFAYVCEAEFPSKPVAEYLTRPHLGGRNEMAARKNMLLAAQQLCKEFTELL 366
Query: 360 AQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKM 419
+QDR+P G SR A +LE +Q+CL+HFSLITHGFG AICAA++A QNY+ E+L +DK
Sbjct: 367 SQDRTPHGTSRLAPVLETNIQNCLSHFSLITHGFGSQAICAAVSALQNYIKEALIVIDKS 426
Query: 420 FLSSVGSGHGET-KASEKDAKHRK 442
+++ ++ K EK KHRK
Sbjct: 427 YMNPGDQSPADSNKTLEKMEKHRK 450
>gi|151301211 transcription factor AP-2 beta-like 1 [Homo sapiens]
Length = 452
Score = 324 bits (831), Expect = 9e-89
Identities = 211/430 (49%), Positives = 253/430 (58%), Gaps = 49/430 (11%)
Query: 31 AYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAP-DAAAAFPHLAGDPYGGLAP 89
AY + PL ++ T EF PYF + PL + + + P + D Y L
Sbjct: 39 AYSSSSPLTYS---TTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYS-LNS 94
Query: 90 LAQPQP--PQAAWAAPRAAARAHEE---PPGLLAPPARALG-LDPRRDYATAVPRLLHGL 143
L Q Q P H L R LG LD R + ++ + HG
Sbjct: 95 LHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSL--MSHGS 152
Query: 144 ADGAHG----LADAPLGLPGLAAAPGLEDLQAMDEPGMSLL---DQSVIKKVPIPSKASS 196
G H L LGL AA G +DLQ E L+ VI++
Sbjct: 153 QYGMHPDQRLLPGPSLGL----AAAGADDLQGSVEAQCGLVLNGQGGVIRR--------- 199
Query: 197 LSALSLAKDSLVGG--ITNPGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNAS 254
GG + NP ++FCSVPGRLSLLSSTSKYKVT+ EV+RRLSPPECLNAS
Sbjct: 200 ------------GGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNAS 247
Query: 255 LLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYV 314
LLGG+LRRAKSKNGGRCLRE+L+++GLNLPAGRRKAANVTLLTSLVEGEA+HLARDFGY
Sbjct: 248 LLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYT 307
Query: 315 CETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALI 374
CETEFPAKA E+L RQH + E +RK M+LA KQICKEF DL++QDRSPLG+SRP I
Sbjct: 308 CETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPI 367
Query: 375 LEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMFLSSVG--SGHGETK 432
L+ +Q LTHFSLITHGFG PAICAAL+ FQ L E L L+K G + G+
Sbjct: 368 LDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGH 427
Query: 433 ASEKDAKHRK 442
A+ + A RK
Sbjct: 428 ANSEKAPLRK 437
>gi|197245373 proline rich 22 isoform 1 [Homo sapiens]
Length = 422
Score = 51.2 bits (121), Expect = 2e-06
Identities = 66/229 (28%), Positives = 87/229 (37%), Gaps = 38/229 (16%)
Query: 12 PDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPD 71
P G+ +A G L P PP H A +F PYFPP P P G D
Sbjct: 104 PAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPE-ALGFVGD 162
Query: 72 AA-AAFPHLAGDPY-GGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPR 129
A AAF L P G APL P P + ++ PP L+ PA P
Sbjct: 163 AGPAAFVELPLPPLEEGPAPLPPPPP------------KENKPPPVLITLPAEP--TLPP 208
Query: 130 RDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIK--- 186
Y+ L H G LA L G A PG+ + PG+S L + +K
Sbjct: 209 DAYSHLQGHLGH--FPGPEPLAFPVKELQGSGARPGV----PLYPPGLSELKVAEVKEGA 262
Query: 187 -------KVPIPSKASSLSALSLAKDSL-----VGGITNPGEVFCSVPG 223
K P ++A +L L +D++ + G + P C VPG
Sbjct: 263 LLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPG 311
>gi|23503299 proline rich 22 isoform 2 [Homo sapiens]
Length = 420
Score = 51.2 bits (121), Expect = 2e-06
Identities = 66/229 (28%), Positives = 87/229 (37%), Gaps = 38/229 (16%)
Query: 12 PDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPD 71
P G+ +A G L P PP H A +F PYFPP P P G D
Sbjct: 102 PAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPE-ALGFVGD 160
Query: 72 AA-AAFPHLAGDPY-GGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPR 129
A AAF L P G APL P P + ++ PP L+ PA P
Sbjct: 161 AGPAAFVELPLPPLEEGPAPLPPPPP------------KENKPPPVLITLPAEP--TLPP 206
Query: 130 RDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIK--- 186
Y+ L H G LA L G A PG+ + PG+S L + +K
Sbjct: 207 DAYSHLQGHLGH--FPGPEPLAFPVKELQGSGARPGV----PLYPPGLSELKVAEVKEGA 260
Query: 187 -------KVPIPSKASSLSALSLAKDSL-----VGGITNPGEVFCSVPG 223
K P ++A +L L +D++ + G + P C VPG
Sbjct: 261 LLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPG 309
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 51.2 bits (121), Expect = 2e-06
Identities = 44/117 (37%), Positives = 46/117 (39%), Gaps = 11/117 (9%)
Query: 22 ARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAG 81
AR+ + A PAPP A AAA PP P P P PP P A A A
Sbjct: 97 ARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAP-PPPPAPVAAAAPARA------- 148
Query: 82 DPYGGLAPLAQPQPPQAAWAAPRA--AARAHEEPPGLLAPPARALGLDPRRDYATAV 136
P A P P A PRA AA PP APPA A PRR AV
Sbjct: 149 -PRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAV 204
Score = 39.3 bits (90), Expect = 0.007
Identities = 39/120 (32%), Positives = 44/120 (36%), Gaps = 11/120 (9%)
Query: 12 PDGLGAAAGGARLSSLPQAAYGPAPPLCHTPA----ATAAAEFQPPYFPPPYPQP----P 63
P G AAA A P PAP PA A AAA PP P P P
Sbjct: 115 PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRA 174
Query: 64 LPYGQAPDAAAAFPHLAGDPYGGLAP---LAQPQPPQAAWAAPRAAARAHEEPPGLLAPP 120
P P A AA P +A AP +A +PP P A + + PP PP
Sbjct: 175 APLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPP 234
Score = 33.1 bits (74), Expect = 0.52
Identities = 24/66 (36%), Positives = 26/66 (39%), Gaps = 4/66 (6%)
Query: 12 PDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPD 71
P + AG R P A PPL P A + Q P PPP PQPP G
Sbjct: 187 PPAVAPPAGPRRAP--PPAVAAREPPLPPPPQPPAPPQQQQP--PPPQPQPPPEGGAVRA 242
Query: 72 AAAAFP 77
AA P
Sbjct: 243 GGAARP 248
Score = 32.7 bits (73), Expect = 0.68
Identities = 28/80 (35%), Positives = 28/80 (35%), Gaps = 21/80 (26%)
Query: 28 PQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGL 87
P A PA P P A AA E P PPP PQPP P P
Sbjct: 187 PPAVAPPAGPRRAPPPAVAARE---PPLPPP-PQPPAP-----------------PQQQQ 225
Query: 88 APLAQPQPPQAAWAAPRAAA 107
P QPQPP A A
Sbjct: 226 PPPPQPQPPPEGGAVRAGGA 245
>gi|19263349 Cbp/p300-interacting transactivator, with Glu/Asp-rich
carboxy-terminal domain, 4 [Homo sapiens]
Length = 184
Score = 50.1 bits (118), Expect = 4e-06
Identities = 50/143 (34%), Positives = 54/143 (37%), Gaps = 36/143 (25%)
Query: 1 MLVHTYSAMERPDGLGAAAGGARLSSLPQ--------------AAYGPAPPLCHTPAATA 46
ML Y ++RP AA G L +LP A GP PP P A A
Sbjct: 6 MLAEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPP--RQPGALA 63
Query: 47 AAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHL--AGDPYGG--LAPLAQPQPPQAAWAA 102
F PP P+P P P AA HL PY G AP P P A
Sbjct: 64 YGAFGPPSSFQPFPAVPPP-------AAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPA 116
Query: 103 PRAAARAHEEPPGLLAPPARALG 125
P AAA PP PPA ALG
Sbjct: 117 PSAAA-----PP----PPAHALG 130
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 49.7 bits (117), Expect = 5e-06
Identities = 53/172 (30%), Positives = 64/172 (37%), Gaps = 31/172 (18%)
Query: 7 SAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPY 66
+ ++ P +GAAA P A P+PP PAA AAA PP P +PP
Sbjct: 236 TVIQTPPFVGAAA--------PPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP 287
Query: 67 GQAPDAAAAFPHLAGDPYGGLAPLA-QPQP-------------PQAAWAAPRAAARAHEE 112
P AA A P A GG A A P P P AA AAP +A
Sbjct: 288 AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESP 347
Query: 113 PPGLLAPPARALGLDPRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAP 164
+ A P A L +TA ++ GA LP AA P
Sbjct: 348 KRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGA---------LPSPAAVP 390
Score = 40.8 bits (94), Expect = 0.002
Identities = 71/250 (28%), Positives = 90/250 (36%), Gaps = 38/250 (15%)
Query: 11 RPDGLGAAA---GGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYG 67
+P G GAA G A L + AA PA L + A A P P Q P G
Sbjct: 188 KPAGPGAAQTLNGSAALLNSHHAA-APAVSLVNNGPA-ALLPLPKPAAPGTVIQTPPFVG 245
Query: 68 QAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLD 127
A A A P P A P PP AP AR PPG A P A
Sbjct: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPP----PAPATLAR----PPGHPAGPPTA---- 293
Query: 128 PRRDYATAVPRLLHGLADGAHGLADAPL----GLPGLAAAPGLEDLQAMDEPGMSL-LDQ 182
A AVP G+ G A AP G G++ PG A PG+ +
Sbjct: 294 -----APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPK 348
Query: 183 SVIKKVP------IPSKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLSSTSKYKV 236
V++ P S +S +A + ++ G + +P V PG + T K
Sbjct: 349 RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPG-----TPTGLPKG 403
Query: 237 TVGEVQRRLS 246
G V + LS
Sbjct: 404 AAGAVTQSLS 413
Score = 40.0 bits (92), Expect = 0.004
Identities = 44/115 (38%), Positives = 46/115 (40%), Gaps = 14/115 (12%)
Query: 12 PDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFP-PPYPQPPL-PYGQA 69
P G A A P AA P PP PA A P P PP P+ PL P G A
Sbjct: 67 PAGAAGAGPAAPAEGAPGAA--PEPP----PAGRARPGGGGPQRPGPPSPRRPLVPAGPA 120
Query: 70 PDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAA-PRAAARAHEEPPGLLAPPARA 123
P AA P P G A P P AA AA P A +P G A ARA
Sbjct: 121 PPAAKLRP-----PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170
Score = 30.8 bits (68), Expect = 2.6
Identities = 39/134 (29%), Positives = 46/134 (34%), Gaps = 22/134 (16%)
Query: 62 PPLPYGQAPDAAAAFPHL-AGDPYGGL----------APLAQPQPPQAAWAAPRAAARAH 110
P P +A A A H+ +G P G AP A P+PP A A P
Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104
Query: 111 EEPPGLL--------APPARALGLDPRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAA 162
PP APPA L P + P + A A G AP G P A
Sbjct: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAP--VPAAAAVAAGPEPAPAG-PAKPA 161
Query: 163 APGLEDLQAMDEPG 176
P +A PG
Sbjct: 162 GPAALAARAGPGPG 175
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 48.9 bits (115), Expect = 9e-06
Identities = 32/103 (31%), Positives = 41/103 (39%), Gaps = 2/103 (1%)
Query: 28 PQAAYGPAPPLCH--TPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYG 85
P P+PP +P+AT + PP PP PP P P + +A P P
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL 761
Query: 86 GLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDP 128
PL P P A+ A + PP L PP +AL P
Sbjct: 762 AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804
Score = 45.4 bits (106), Expect = 1e-04
Identities = 52/184 (28%), Positives = 67/184 (36%), Gaps = 21/184 (11%)
Query: 35 APPLCHTPAATAAAEFQPPYFPPPYPQPPLPYG---QAPDAAAAFPHLAGDPYGGLAPLA 91
A P P A A Q P+ PPP P P+ P + +A P P PL
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
Query: 92 QPQPPQAAWAAPRAAARAHEEPPGLLAPPARA----LGLDPRRDYATAVPRLLHGLA--- 144
P P A+ +A + PP L APP + P AT PR+ LA
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 145 -----DGAHGLADAPLGLPGLAAAPGL--EDLQAMDEPGMSLLDQSVIKKVPIPSKASSL 197
L +PL P A P L LQA+ P S Q+ PS + +
Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS----PSASLPM 821
Query: 198 SALS 201
S L+
Sbjct: 822 SPLA 825
Score = 40.8 bits (94), Expect = 0.002
Identities = 47/143 (32%), Positives = 52/143 (36%), Gaps = 17/143 (11%)
Query: 24 LSSLPQAAYGP-----AP---PLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAA 75
L +LP A P AP P TP A Q P P P P P A A
Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594
Query: 76 FPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPRRDYATA 135
P LA P GL P PP + A P A P L APP+ P AT
Sbjct: 595 PPALASPPLQGL-----PSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS-PPLSPLATP 648
Query: 136 VPRLLHGLADGAHGLADAPLGLP 158
P+ + LA H L AP P
Sbjct: 649 SPQAPNALA--VH-LLQAPFSPP 668
Score = 35.0 bits (79), Expect = 0.14
Identities = 44/147 (29%), Positives = 53/147 (36%), Gaps = 28/147 (19%)
Query: 28 PQAAYGPAPPLCH--TPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYG 85
P P+PP +P+AT P PP PP P P + A P P
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Query: 86 GLAPL-AQPQPPQA----AWAAPRA-------AARAHEEPPGLLA--------PPARALG 125
PL A P PP + A +P A A + PP L A PPA
Sbjct: 793 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 852
Query: 126 LDPRR------DYATAVPRLLHGLADG 146
PRR D + + PRL LA G
Sbjct: 853 QAPRRPPTPGPDTSVSGPRLTLALAPG 879
Score = 33.1 bits (74), Expect = 0.52
Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 21/133 (15%)
Query: 44 ATAAAEFQPPYFPPPYP----------QPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQ- 92
A+ + +P PP P PPL +P + L P L+ LA
Sbjct: 439 ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498
Query: 93 -PQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPRRDYATAVPRLLHGLADGAHGLA 151
PQ P ++ P ++ PP L PPA +L P + + P L A
Sbjct: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPA-SLTTPPLENLPSLAPPPLQ--------TA 549
Query: 152 DAPLGLPGLAAAP 164
APL P L P
Sbjct: 550 SAPLTTPHLETPP 562
Score = 31.2 bits (69), Expect = 2.0
Identities = 37/134 (27%), Positives = 46/134 (34%), Gaps = 17/134 (12%)
Query: 37 PLCHTPAATAAAEFQP--PYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQ-- 92
PL +P AT + P PP PLP P A P P P Q
Sbjct: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357
Query: 93 PQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPRRDYATAVPRLLHGLADGAHGLAD 152
P PP A P + A PP + PP +A P ++ H L +
Sbjct: 358 PSPP----ATPPSQA-----PPSMTTPPMQA----PPSLQTIPPIQVPHSLTSPSLQAPP 404
Query: 153 APLGLPGLAAAPGL 166
+PL L L A L
Sbjct: 405 SPLALSSLQATTSL 418
Score = 30.8 bits (68), Expect = 2.6
Identities = 51/179 (28%), Positives = 61/179 (34%), Gaps = 27/179 (15%)
Query: 4 HTYSAMERPDGL---------GAAAG---GARLSSLPQAAY--GPAPPLCHTPAATAAAE 49
H+ SA P+ L GAAA A L++ AA+ GPAPPL A A
Sbjct: 900 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA--- 956
Query: 50 FQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARA 109
P P PP + D G AP A P + +AAA A
Sbjct: 957 --------PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 1008
Query: 110 HEEPPGLLAPPARALGLDPRRDYATAVPRLLHG--LADGAHGLADAPLGLPGLAAAPGL 166
AR L A+ V LL L A G A G PG A G+
Sbjct: 1009 GAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGV 1067
Score = 30.4 bits (67), Expect = 3.4
Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 7/116 (6%)
Query: 8 AMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYG 67
A E P +AG R +S P P+P + A P P P+PP G
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTE-G 204
Query: 68 QAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARA 123
++A H +P +P A+ + P A R A+R+ L+ PAR+
Sbjct: 205 PRKSVSSASEHSTTEP----SPAAR-RRPSAGGGLQRPASRSLSSSATPLSSPARS 255
>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
sapiens]
Length = 245
Score = 47.8 bits (112), Expect = 2e-05
Identities = 40/122 (32%), Positives = 45/122 (36%), Gaps = 30/122 (24%)
Query: 28 PQAAYGPAPPLCHTPAATAAAEFQP------PYFPP--PYPQPPLPYGQAPDAAAA---- 75
P A + P+ P C P A P PY P P+P+ P PYG D AAA
Sbjct: 84 PPAPFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLG 143
Query: 76 ----------FPHLAGD------PYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAP 119
P + G PY P P PPQA AAP PPG P
Sbjct: 144 PWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGAAPPVPWGT--VPPGAWGP 201
Query: 120 PA 121
PA
Sbjct: 202 PA 203
Score = 32.0 bits (71), Expect = 1.2
Identities = 32/104 (30%), Positives = 35/104 (33%), Gaps = 10/104 (9%)
Query: 25 SSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPY 84
S LP +A P PA T PP PPP P P P P + P G PY
Sbjct: 51 SGLPPSATPSTVPF--GPAPTGMYPSVPPTGPPPGPPAPFP----PSGPSCPP--PGGPY 102
Query: 85 GGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDP 128
AP P + P P G PA A L P
Sbjct: 103 P--APTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGP 144
Score = 30.0 bits (66), Expect = 4.4
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 14/81 (17%)
Query: 6 YSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPP--YPQPP 63
Y A P GAA ++P A+GP P PA T + +P P YP P
Sbjct: 174 YPAPPPPQAPGAAPP-VPWGTVPPGAWGPPAPY---PAPTGS-------YPTPGLYPTPS 222
Query: 64 LPYGQAPDAAAAFPHLAGDPY 84
P+ Q P + P + G P+
Sbjct: 223 NPF-QVPSGPSGAPPMPGGPH 242
Score = 29.3 bits (64), Expect = 7.5
Identities = 35/116 (30%), Positives = 42/116 (36%), Gaps = 18/116 (15%)
Query: 2 LVHTYSAMERPDGLGAAAGGARLSSLPQA-AYGPAPPLCHTPAATAAAEFQPPYFPPPYP 60
L Y A P G +SS P A G P + P + PY PP P
Sbjct: 126 LPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPG-----PYPAPPPP 180
Query: 61 Q-----PPLPYGQAPDAA----AAFPHLAGD-PYGGLAPLAQPQPPQAAWAAPRAA 106
Q PP+P+G P A A +P G P GL P P P + P A
Sbjct: 181 QAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTPGLYP--TPSNPFQVPSGPSGA 234
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 47.4 bits (111), Expect = 3e-05
Identities = 38/130 (29%), Positives = 47/130 (36%), Gaps = 11/130 (8%)
Query: 35 APPLCHTPAATAAAEFQPPYFPPPYPQPPLPYG---QAPDAAAAFPHLAGDPYGGLAPLA 91
A P P A A Q P+ PPP P P+ P + +A P P PL
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480
Query: 92 QPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPRRDYATAVPRLLHGLADGAHGLA 151
P P A+ +A + PP L APP + P+ A A P L L
Sbjct: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL--------QALP 532
Query: 152 DAPLGLPGLA 161
P PG A
Sbjct: 533 SPPASFPGQA 542
Score = 45.1 bits (105), Expect = 1e-04
Identities = 52/184 (28%), Positives = 68/184 (36%), Gaps = 25/184 (13%)
Query: 34 PAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFP----------HLAGDP 83
P+PPL +P AT + P PP PP P P + A P HL P
Sbjct: 382 PSPPL--SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 439
Query: 84 YG--GLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARA----LGLDPRRDYATAVP 137
+ P+ P P A+ +A + PP L APP + P AT P
Sbjct: 440 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499
Query: 138 RLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIKKVPIPSKASSL 197
+ LA LA P P A P LQA+ P S Q+ PS + +
Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATP---PLQALPSPPASFPGQAPFS----PSASLPM 552
Query: 198 SALS 201
S L+
Sbjct: 553 SPLA 556
Score = 43.1 bits (100), Expect = 5e-04
Identities = 35/102 (34%), Positives = 46/102 (45%), Gaps = 17/102 (16%)
Query: 29 QAAYGP--APPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGG 86
QA + P +PP+ +P+AT ++ P PP PP P P + +A P P
Sbjct: 449 QAPFSPPASPPV--SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--- 503
Query: 87 LAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDP 128
PLA P P Q A P+A PP L PP +AL P
Sbjct: 504 --PLAAP-PLQLAKPPPQA-------PPALATPPLQALPSPP 535
Score = 36.2 bits (82), Expect = 0.061
Identities = 40/135 (29%), Positives = 48/135 (35%), Gaps = 23/135 (17%)
Query: 35 APPLCHTPAATAAAEFQPPYFPPPYPQPPL---PYGQAPDAAAAFPHLAGDPYGGLAPLA 91
APPL P+ A+ P PPP PPL P A A P LA P L
Sbjct: 476 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535
Query: 92 QPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGL--------------DPRR------D 131
P QA ++ + + P APP A L PRR D
Sbjct: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 595
Query: 132 YATAVPRLLHGLADG 146
+ + PRL LA G
Sbjct: 596 TSVSGPRLTLALAPG 610
Score = 30.8 bits (68), Expect = 2.6
Identities = 51/179 (28%), Positives = 61/179 (34%), Gaps = 27/179 (15%)
Query: 4 HTYSAMERPDGL---------GAAAG---GARLSSLPQAAY--GPAPPLCHTPAATAAAE 49
H+ SA P+ L GAAA A L++ AA+ GPAPPL A A
Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA--- 687
Query: 50 FQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARA 109
P P PP + D G AP A P + +AAA A
Sbjct: 688 --------PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 739
Query: 110 HEEPPGLLAPPARALGLDPRRDYATAVPRLLHG--LADGAHGLADAPLGLPGLAAAPGL 166
AR L A+ V LL L A G A G PG A G+
Sbjct: 740 GAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGV 798
Score = 30.4 bits (67), Expect = 3.4
Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 7/116 (6%)
Query: 8 AMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYG 67
A E P +AG R +S P P+P + A P P P+PP G
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTE-G 204
Query: 68 QAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARA 123
++A H +P +P A+ + P A R A+R+ L+ PAR+
Sbjct: 205 PRKSVSSASEHSTTEP----SPAAR-RRPSAGGGLQRPASRSLSSSATPLSSPARS 255
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 47.4 bits (111), Expect = 3e-05
Identities = 38/130 (29%), Positives = 47/130 (36%), Gaps = 11/130 (8%)
Query: 35 APPLCHTPAATAAAEFQPPYFPPPYPQPPLPYG---QAPDAAAAFPHLAGDPYGGLAPLA 91
A P P A A Q P+ PPP P P+ P + +A P P PL
Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441
Query: 92 QPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPRRDYATAVPRLLHGLADGAHGLA 151
P P A+ +A + PP L APP + P+ A A P L L
Sbjct: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL--------QALP 493
Query: 152 DAPLGLPGLA 161
P PG A
Sbjct: 494 SPPASFPGQA 503
Score = 45.1 bits (105), Expect = 1e-04
Identities = 52/184 (28%), Positives = 68/184 (36%), Gaps = 25/184 (13%)
Query: 34 PAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFP----------HLAGDP 83
P+PPL +P AT + P PP PP P P + A P HL P
Sbjct: 343 PSPPL--SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400
Query: 84 YG--GLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARA----LGLDPRRDYATAVP 137
+ P+ P P A+ +A + PP L APP + P AT P
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460
Query: 138 RLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIKKVPIPSKASSL 197
+ LA LA P P A P LQA+ P S Q+ PS + +
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATP---PLQALPSPPASFPGQAPFS----PSASLPM 513
Query: 198 SALS 201
S L+
Sbjct: 514 SPLA 517
Score = 43.1 bits (100), Expect = 5e-04
Identities = 35/102 (34%), Positives = 46/102 (45%), Gaps = 17/102 (16%)
Query: 29 QAAYGP--APPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGG 86
QA + P +PP+ +P+AT ++ P PP PP P P + +A P P
Sbjct: 410 QAPFSPPASPPV--SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--- 464
Query: 87 LAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDP 128
PLA P P Q A P+A PP L PP +AL P
Sbjct: 465 --PLAAP-PLQLAKPPPQA-------PPALATPPLQALPSPP 496
Score = 36.2 bits (82), Expect = 0.061
Identities = 40/135 (29%), Positives = 48/135 (35%), Gaps = 23/135 (17%)
Query: 35 APPLCHTPAATAAAEFQPPYFPPPYPQPPL---PYGQAPDAAAAFPHLAGDPYGGLAPLA 91
APPL P+ A+ P PPP PPL P A A P LA P L
Sbjct: 437 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496
Query: 92 QPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGL--------------DPRR------D 131
P QA ++ + + P APP A L PRR D
Sbjct: 497 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 556
Query: 132 YATAVPRLLHGLADG 146
+ + PRL LA G
Sbjct: 557 TSVSGPRLTLALAPG 571
Score = 30.8 bits (68), Expect = 2.6
Identities = 51/179 (28%), Positives = 61/179 (34%), Gaps = 27/179 (15%)
Query: 4 HTYSAMERPDGL---------GAAAG---GARLSSLPQAAY--GPAPPLCHTPAATAAAE 49
H+ SA P+ L GAAA A L++ AA+ GPAPPL A A
Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA--- 648
Query: 50 FQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARA 109
P P PP + D G AP A P + +AAA A
Sbjct: 649 --------PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 700
Query: 110 HEEPPGLLAPPARALGLDPRRDYATAVPRLLHG--LADGAHGLADAPLGLPGLAAAPGL 166
AR L A+ V LL L A G A G PG A G+
Sbjct: 701 GAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGV 759
Score = 30.4 bits (67), Expect = 3.4
Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 7/116 (6%)
Query: 8 AMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYG 67
A E P +AG R +S P P+P + A P P P+PP G
Sbjct: 138 ATEAPKRSALSAGARRDTSGPTPGT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTE-G 195
Query: 68 QAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARA 123
++A H +P +P A+ + P A R A+R+ L+ PAR+
Sbjct: 196 PRKSVSSASEHSTTEP----SPAAR-RRPSAGGGLQRPASRSLSSSATPLSSPARS 246
>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
potassium channel 4 [Homo sapiens]
Length = 1203
Score = 46.2 bits (108), Expect = 6e-05
Identities = 58/234 (24%), Positives = 86/234 (36%), Gaps = 58/234 (24%)
Query: 28 PQAAY-GPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGG 86
PQAA PAPP A + PPP P ++P ++ P G P G
Sbjct: 936 PQAAQPSPAPP-----GARGGLGLPEHFLPPP------PSSRSPSSS---PGQLGQPPGE 981
Query: 87 LA-------------PLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPRRDYA 133
L+ P QP+PP A A+ P G L+PP + G P R +
Sbjct: 982 LSLGLATGPLSTPETPPRQPEPPSLVAGASGGASPVGFTPRGGLSPPGHSPG--PPRTFP 1039
Query: 134 TAVPRLLHGLADGAHGLADAP-------------LGLPGLAAAPGLEDLQ--AMDEPGMS 178
+A PR A G+HG P G P L +DL+ + +P +
Sbjct: 1040 SAPPR-----ASGSHGSLLLPPASSPPPPQVPQRRGTPPLTPGRLTQDLKLISASQPALP 1094
Query: 179 LLDQSVIKKVPIPSKASSLSALSL--------AKDSLVGGITNPGEVFCSVPGR 224
+++ S S++A L GG+ PG + ++PG+
Sbjct: 1095 QDGAQTLRRASPHSSGESMAAFPLFPRAGGGSGGSGSSGGLGPPGRPYGAIPGQ 1148
>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 46.2 bits (108), Expect = 6e-05
Identities = 31/89 (34%), Positives = 35/89 (39%), Gaps = 6/89 (6%)
Query: 34 PAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPY------GQAPDAAAAFPHLAGDPYGGL 87
PAP TP T PP P P P P G P A P A P G
Sbjct: 587 PAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPP 646
Query: 88 APLAQPQPPQAAWAAPRAAARAHEEPPGL 116
P+ P PPQ A + AA++ PPGL
Sbjct: 647 GPIPVPAPPQIATSTSLLAAQSLVPPPGL 675
Score = 29.3 bits (64), Expect = 7.5
Identities = 33/100 (33%), Positives = 37/100 (37%), Gaps = 14/100 (14%)
Query: 17 AAAGGARLSSLPQAAYGPAPPLCHTPAA-TAAAEFQPPYFPPPYPQPPLPYGQAPD---- 71
A +G + S P PAPP C PA T QPP P P PP G D
Sbjct: 424 APSGDCAMESPP-----PAPPPCPGPAPDTIDLTLQPPP-PVSEPAPPKKDGAISDNTKA 477
Query: 72 --AAAAFPHLAGDPYGG-LAPLAQPQPPQAAWAAPRAAAR 108
AA L G APL P+P + A R R
Sbjct: 478 ALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQRER 517
>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 46.2 bits (108), Expect = 6e-05
Identities = 31/89 (34%), Positives = 35/89 (39%), Gaps = 6/89 (6%)
Query: 34 PAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPY------GQAPDAAAAFPHLAGDPYGGL 87
PAP TP T PP P P P P G P A P A P G
Sbjct: 587 PAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPP 646
Query: 88 APLAQPQPPQAAWAAPRAAARAHEEPPGL 116
P+ P PPQ A + AA++ PPGL
Sbjct: 647 GPIPVPAPPQIATSTSLLAAQSLVPPPGL 675
Score = 29.3 bits (64), Expect = 7.5
Identities = 33/100 (33%), Positives = 37/100 (37%), Gaps = 14/100 (14%)
Query: 17 AAAGGARLSSLPQAAYGPAPPLCHTPAA-TAAAEFQPPYFPPPYPQPPLPYGQAPD---- 71
A +G + S P PAPP C PA T QPP P P PP G D
Sbjct: 424 APSGDCAMESPP-----PAPPPCPGPAPDTIDLTLQPPP-PVSEPAPPKKDGAISDNTKA 477
Query: 72 --AAAAFPHLAGDPYGG-LAPLAQPQPPQAAWAAPRAAAR 108
AA L G APL P+P + A R R
Sbjct: 478 ALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQRER 517
>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 46.2 bits (108), Expect = 6e-05
Identities = 31/89 (34%), Positives = 35/89 (39%), Gaps = 6/89 (6%)
Query: 34 PAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPY------GQAPDAAAAFPHLAGDPYGGL 87
PAP TP T PP P P P P G P A P A P G
Sbjct: 587 PAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPP 646
Query: 88 APLAQPQPPQAAWAAPRAAARAHEEPPGL 116
P+ P PPQ A + AA++ PPGL
Sbjct: 647 GPIPVPAPPQIATSTSLLAAQSLVPPPGL 675
Score = 29.3 bits (64), Expect = 7.5
Identities = 33/100 (33%), Positives = 37/100 (37%), Gaps = 14/100 (14%)
Query: 17 AAAGGARLSSLPQAAYGPAPPLCHTPAA-TAAAEFQPPYFPPPYPQPPLPYGQAPD---- 71
A +G + S P PAPP C PA T QPP P P PP G D
Sbjct: 424 APSGDCAMESPP-----PAPPPCPGPAPDTIDLTLQPPP-PVSEPAPPKKDGAISDNTKA 477
Query: 72 --AAAAFPHLAGDPYGG-LAPLAQPQPPQAAWAAPRAAAR 108
AA L G APL P+P + A R R
Sbjct: 478 ALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQRER 517
>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
Length = 677
Score = 46.2 bits (108), Expect = 6e-05
Identities = 31/89 (34%), Positives = 35/89 (39%), Gaps = 6/89 (6%)
Query: 34 PAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPY------GQAPDAAAAFPHLAGDPYGGL 87
PAP TP T PP P P P P G P A P A P G
Sbjct: 448 PAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPP 507
Query: 88 APLAQPQPPQAAWAAPRAAARAHEEPPGL 116
P+ P PPQ A + AA++ PPGL
Sbjct: 508 GPIPVPAPPQIATSTSLLAAQSLVPPPGL 536
Score = 29.3 bits (64), Expect = 7.5
Identities = 33/100 (33%), Positives = 37/100 (37%), Gaps = 14/100 (14%)
Query: 17 AAAGGARLSSLPQAAYGPAPPLCHTPAA-TAAAEFQPPYFPPPYPQPPLPYGQAPD---- 71
A +G + S P PAPP C PA T QPP P P PP G D
Sbjct: 285 APSGDCAMESPP-----PAPPPCPGPAPDTIDLTLQPPP-PVSEPAPPKKDGAISDNTKA 338
Query: 72 --AAAAFPHLAGDPYGG-LAPLAQPQPPQAAWAAPRAAAR 108
AA L G APL P+P + A R R
Sbjct: 339 ALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQRER 378
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 44.7 bits (104), Expect = 2e-04
Identities = 51/170 (30%), Positives = 56/170 (32%), Gaps = 24/170 (14%)
Query: 15 LGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQP---PLPYGQAPD 71
+ A GG R P A P PP P A + QPP PPP P P P P Q P
Sbjct: 1 MDARGGGGRPGESPGATPAPGPP---PPPPPAPPQQQPPPPPPPAPPPGPGPAP-PQHPP 56
Query: 72 AAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPRRD 131
A A P A D G L P AA+ A P G + R
Sbjct: 57 RAEALPPEAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNG-----------ECGRG 105
Query: 132 YATAVPRLLHGLADG------AHGLADAPLGLPGLAAAPGLEDLQAMDEP 175
P G A G G A P PG A G E+ EP
Sbjct: 106 EPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSEEAGPAGEP 155
Score = 32.0 bits (71), Expect = 1.2
Identities = 35/109 (32%), Positives = 44/109 (40%), Gaps = 18/109 (16%)
Query: 56 PPPYPQP------PLPYGQAPDAAAAFPHLAGDPYGGL--APLAQPQPP--QAAWAAPRA 105
PPP P P P P P A A+ PYGGL APLA P P + + A+
Sbjct: 761 PPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPL 820
Query: 106 AARAHEEPPGLLAPPARALGLDPRRDYATAVPRLLHGLADGAHGLADAP 154
+A P G P A R +++ PRL G A A +P
Sbjct: 821 SASQPSLPHGAPGPAAST------RPASSSTPRL--GPTPAARAAAPSP 861
Score = 29.6 bits (65), Expect = 5.7
Identities = 29/98 (29%), Positives = 36/98 (36%), Gaps = 8/98 (8%)
Query: 12 PDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPD 71
P G A+ R S YG P A A P QP LP+G
Sbjct: 780 PPGAPASPRAPRTSP-----YGGLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAPGP 834
Query: 72 AAAAFPHLAGDPYGGLAPLAQ---PQPPQAAWAAPRAA 106
AA+ P + P G P A+ P P + A+P AA
Sbjct: 835 AASTRPASSSTPRLGPTPAARAAAPSPDRRDSASPGAA 872
Score = 28.9 bits (63), Expect = 9.8
Identities = 37/124 (29%), Positives = 45/124 (36%), Gaps = 15/124 (12%)
Query: 55 FPPPYPQPPLPYGQAP---DAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHE 111
FPPP P P + A AA +F P G L P+ + P AA +
Sbjct: 714 FPPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASPG 773
Query: 112 EPPGLLAPPARALGLDPRRDYATAVPRL-LHGLADGAHGLADA-----------PLGLPG 159
PP P A A PR +P L G A A L+ A P G PG
Sbjct: 774 PPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAPG 833
Query: 160 LAAA 163
AA+
Sbjct: 834 PAAS 837
>gi|57165375 glutamate receptor, ionotropic, N-methyl
D-aspartate-associated protein 1 [Homo sapiens]
Length = 371
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 6/102 (5%)
Query: 33 GPAPPL--CHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPH----LAGDPYGG 86
GP PP+ P A QPP+ P PY QP P+G +P +P G P G
Sbjct: 24 GPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYPHGPSPYPQGGYPQGPYPQGGYPQGP 83
Query: 87 LAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDP 128
PQ P P+ PP P G DP
Sbjct: 84 YPQEGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDP 125
Score = 30.4 bits (67), Expect = 3.4
Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 7/81 (8%)
Query: 38 LCHTPAATAAAEFQPPYFP--PPYPQPPLP-YGQAPDAAAAFPHLAGDPYGGLAPLAQPQ 94
+ H + + + PP P P PQPP+P Y Q P A +P P +P QP
Sbjct: 1 MSHEKSFLVSGDNYPPPNPGYPGGPQPPMPPYAQPPYPGAPYPQPPFQP----SPYGQPG 56
Query: 95 PPQAAWAAPRAAARAHEEPPG 115
P P+ P G
Sbjct: 57 YPHGPSPYPQGGYPQGPYPQG 77
>gi|57165373 glutamate receptor, ionotropic, N-methyl
D-aspartate-associated protein 1 [Homo sapiens]
Length = 371
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 6/102 (5%)
Query: 33 GPAPPL--CHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPH----LAGDPYGG 86
GP PP+ P A QPP+ P PY QP P+G +P +P G P G
Sbjct: 24 GPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYPHGPSPYPQGGYPQGPYPQGGYPQGP 83
Query: 87 LAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDP 128
PQ P P+ PP P G DP
Sbjct: 84 YPQEGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDP 125
Score = 30.4 bits (67), Expect = 3.4
Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 7/81 (8%)
Query: 38 LCHTPAATAAAEFQPPYFP--PPYPQPPLP-YGQAPDAAAAFPHLAGDPYGGLAPLAQPQ 94
+ H + + + PP P P PQPP+P Y Q P A +P P +P QP
Sbjct: 1 MSHEKSFLVSGDNYPPPNPGYPGGPQPPMPPYAQPPYPGAPYPQPPFQP----SPYGQPG 56
Query: 95 PPQAAWAAPRAAARAHEEPPG 115
P P+ P G
Sbjct: 57 YPHGPSPYPQGGYPQGPYPQG 77
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 1/88 (1%)
Query: 34 PAPPLCHTPAATAAAEFQPPYFPPPYPQP-PLPYGQAPDAAAAFPHLAGDPYGGLAPLAQ 92
P P C TPA E P+ PP+ P P+P + +A P P G P A+
Sbjct: 640 PMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSAR 699
Query: 93 PQPPQAAWAAPRAAARAHEEPPGLLAPP 120
P PP A + PP LL P
Sbjct: 700 PGPPTTANHLGLSVPGLVSVPPRLLPGP 727
Score = 32.7 bits (73), Expect = 0.68
Identities = 28/88 (31%), Positives = 32/88 (36%), Gaps = 12/88 (13%)
Query: 36 PPLCHTPAATAAAEFQPPYFP--PPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQP 93
PPL P + A PP P PP PP+P + P+ A P G L P P
Sbjct: 796 PPLPPPPPSGATP---PPIAPTGPPTASPPVPAKEEPEELPAAP-------GPLPPPPPP 845
Query: 94 QPPQAAWAAPRAAARAHEEPPGLLAPPA 121
PP E PG PPA
Sbjct: 846 PPPVPGPVTLPPPQLVPEGTPGGGGPPA 873
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 42.4 bits (98), Expect = 9e-04
Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 10/97 (10%)
Query: 20 GGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPY-PQPPLPYGQAPDAAAAFPH 78
G L SLP +GP PA + A + PP PPP+ PPL G P A +
Sbjct: 253 GATALQSLP--GFGP-------PAQSLPASYTPPPPPPPFLNSPPLGPGLQPLAPPPPSY 303
Query: 79 LAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPG 115
G +G PL + P ++ AA R A+ H + G
Sbjct: 304 PCGPGFGDKFPLDEADPRNSSIAALRLKAKEHIQAIG 340
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 42.4 bits (98), Expect = 9e-04
Identities = 60/224 (26%), Positives = 79/224 (35%), Gaps = 9/224 (4%)
Query: 42 PAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWA 101
P AT QPP PP PP Q P L P L P A P+PP +
Sbjct: 440 PQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPL-SLPPDAAPKPPIPIQS 498
Query: 102 APRAAARAHEEPPGLLAPPARALGLDPRRDYATAVPRLLHGLADG-AHGLADAPLGLPGL 160
P A +PP L A A P V G A A GLA +P
Sbjct: 499 KPPVAP---IKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTS 555
Query: 161 AAAPG-LEDLQA--MDEPGMSLLDQSVIKKVPIPSKASSLSALSLAKDSLVGGITNPGEV 217
PG ++ QA P S ++ + P + +L+ + + GG T V
Sbjct: 556 RGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPV 615
Query: 218 FCSVPGRLSLLSSTSKYKVTVGEVQRRL-SPPECLNASLLGGVL 260
VP + S K V+R+ S E + S LG +L
Sbjct: 616 VAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSML 659
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 42.4 bits (98), Expect = 9e-04
Identities = 37/110 (33%), Positives = 43/110 (39%), Gaps = 14/110 (12%)
Query: 24 LSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAF---PHLA 80
L+ LP A APP P AAA P PPP P PP P +AP AA P
Sbjct: 746 LADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAV 805
Query: 81 GDPYGGLAPLAQPQPPQAAW----------AAPRAAARAHEEPPGLLAPP 120
P GL+ P+P + + A P A E P APP
Sbjct: 806 ASPGSGLSS-PGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPP 854
>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
Length = 841
Score = 42.4 bits (98), Expect = 9e-04
Identities = 49/175 (28%), Positives = 65/175 (37%), Gaps = 15/175 (8%)
Query: 7 SAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPY 66
S ++P L A S+LP G TP T E PP+ +PPL
Sbjct: 287 SPPQQPHALPPHAHRRPASALPSRRDG-------TPTKTTPCEIPPPFPNLLQHRPPLLA 339
Query: 67 GQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGL 126
+A+ P GD L L + P + AP+ AR E PP PPA L L
Sbjct: 340 FPQAKSASRTP---GDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLL 396
Query: 127 ----DPRRDYATAVPRLLHGLADGAHGLADA-PLGLPGLAAAPGLEDLQAMDEPG 176
R ++T +P G G L ++ + P A AP A PG
Sbjct: 397 LGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPG 451
Score = 28.9 bits (63), Expect = 9.8
Identities = 24/68 (35%), Positives = 26/68 (38%), Gaps = 12/68 (17%)
Query: 57 PPYPQPPLPYGQAPDAAAAFPHLAG---DPYGGLAPLAQPQPPQAAWAAPRAAARAHEEP 113
PP P P+G A AAA H G P+ P P P W P AA
Sbjct: 505 PPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLPDPTVGPLTP--LWTYPATAA------ 556
Query: 114 PGLLAPPA 121
GL PPA
Sbjct: 557 -GLKRPPA 563
>gi|208431824 forkhead box I3 [Homo sapiens]
Length = 420
Score = 42.0 bits (97), Expect = 0.001
Identities = 55/165 (33%), Positives = 66/165 (40%), Gaps = 30/165 (18%)
Query: 42 PAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPH--LAGDPYGGLAPLAQPQPPQAA 99
PAATAAA PP PY L AP AAAA P+ L G GG PP AA
Sbjct: 20 PAATAAAPGAPPAARAPY---GLADYAAPPAAAANPYLWLNGPGVGG--------PPSAA 68
Query: 100 WAAPRAAARAHEEPPGLLAPPARALGLDPRRDYATAVPRLLHGLADGAHGLADAPLGLPG 159
AA A A PP PP A G P L A G G + P P
Sbjct: 69 AAAAAAYLGAPPPPP----PPGAAAG-----------PFLQPPPAAGTFGCSQRPFAQPA 113
Query: 160 LAAAPGLEDLQAMDEPG-MSLLD-QSVIKKVPIPSKASSLSALSL 202
AA E G +S+ + ++K V P S+L A+++
Sbjct: 114 PAAPASPAAPAGPGELGWLSMASREDLMKMVRPPYSYSALIAMAI 158
Score = 29.3 bits (64), Expect = 7.5
Identities = 22/69 (31%), Positives = 26/69 (37%), Gaps = 1/69 (1%)
Query: 16 GAAAGGA-RLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAA 74
G GG ++ AAY APP P A A QPP + P+ Q AA
Sbjct: 58 GPGVGGPPSAAAAAAAAYLGAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAAP 117
Query: 75 AFPHLAGDP 83
A P P
Sbjct: 118 ASPAAPAGP 126
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,992,949
Number of Sequences: 37866
Number of extensions: 1209805
Number of successful extensions: 11171
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 809
Number of HSP's that attempted gapping in prelim test: 7432
Number of HSP's gapped (non-prelim): 3075
length of query: 442
length of database: 18,247,518
effective HSP length: 105
effective length of query: 337
effective length of database: 14,271,588
effective search space: 4809525156
effective search space used: 4809525156
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.