Search of human proteins with 194328777

Search of human proteins with 194328777

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194328777 poly (ADP-ribose) polymerase family, member 11
[Homo sapiens]
         (338 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Hom...   717   0.0  
gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens]              221   9e-58
gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens]    148   6e-36
gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo sap...   138   8e-33
gi|22749259 poly (ADP-ribose) polymerase family, member 15 isofo...   123   2e-28
gi|165377137 poly (ADP-ribose) polymerase family, member 15 isof...   123   2e-28
gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Hom...   117   1e-26
gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Hom...    89   4e-18
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    64   3e-10
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    62   7e-10
gi|226371716 poly (ADP-ribose) polymerase family, member 9 isofo...    51   2e-06
gi|226371714 poly (ADP-ribose) polymerase family, member 9 isofo...    51   2e-06
gi|226371712 poly (ADP-ribose) polymerase family, member 9 isofo...    51   2e-06
gi|226371710 poly (ADP-ribose) polymerase family, member 9 isofo...    51   2e-06
gi|226371706 poly (ADP-ribose) polymerase family, member 9 isofo...    51   2e-06
gi|27477138 zinc finger antiviral protein isoform 2 [Homo sapiens]     44   2e-04
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       36   0.043
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo...    34   0.21 
gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo...    34   0.21 
gi|20270349 MIT, microtubule interacting and transport, domain c...    33   0.36 
gi|21389569 tektin 5 [Homo sapiens]                                    33   0.47 
gi|110825963 poly (ADP-ribose) polymerase family, member 2 isofo...    32   0.81 
gi|110825961 poly (ADP-ribose) polymerase family, member 2 isofo...    32   0.81 
gi|148237498 deltex 4 homolog [Homo sapiens]                           31   1.4  
gi|56550051 ubiquitin specific protease 39 [Homo sapiens]              29   5.2  
gi|118600963 Nik related kinase [Homo sapiens]                         29   5.2  
gi|209977117 unc-5 homolog D [Homo sapiens]                            29   6.8  
gi|148612805 pigeon homolog [Homo sapiens]                             28   8.9  

>gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Homo
           sapiens]
          Length = 338

 Score =  717 bits (1852), Expect = 0.0
 Identities = 338/338 (100%), Positives = 338/338 (100%)

Query: 1   MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS 60
           MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS
Sbjct: 1   MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS 60

Query: 61  EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN 120
           EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN
Sbjct: 61  EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN 120

Query: 121 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF 180
           EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF
Sbjct: 121 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF 180

Query: 181 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD 240
           FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD
Sbjct: 181 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD 240

Query: 241 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK 300
           AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK
Sbjct: 241 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK 300

Query: 301 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH 338
           DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH
Sbjct: 301 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH 338


>gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens]
          Length = 701

 Score =  221 bits (562), Expect = 9e-58
 Identities = 118/323 (36%), Positives = 183/323 (56%), Gaps = 37/323 (11%)

Query: 32  TQWGWFYLAECGKWHMF--QPDTNSQCSVSSEDIEKSF-------KTNPCGSISFTTSKF 82
           T W W++  E G W  +  Q   +   +VSS D+EK++             ++ F   K 
Sbjct: 375 TDWIWYWSDEFGSWQEYGRQGTVHPVTTVSSSDVEKAYLAYCTPGSDGQAATLKFQAGKH 434

Query: 83  SYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICE---NEAIP----MPPHWENVNTQ 135
           +Y++DF    Q NL  G  + + R P  +S          N   P    +P +W++    
Sbjct: 435 NYELDFKAFVQKNLVYGTTKKVCRRPKYVSPQDVTTMQTCNTKFPGPKSIPDYWDSSALP 494

Query: 136 VP-YQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGV 194
            P +Q I L + + EY +V NLF +T+    +++I+R+QNL LWE +  +K Q++K+ G 
Sbjct: 495 DPGFQKITLSSSSEEYQKVWNLFNRTLPFYFVQKIERVQNLALWEVYQWQKGQMQKQNGG 554

Query: 195 PQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYSSRFCKDDIKH 254
             ++E+ LFHGTS+ FV+AIC  NFDWR+ G+HG  +GKG+YFARDAAYS  + K D   
Sbjct: 555 KAVDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAYSHHYSKSDT-- 612

Query: 255 GNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDD 314
               Q H              +MFLARVL+G+++ G++ ++RPP+K+G     YDSCV+ 
Sbjct: 613 ----QTH--------------TMFLARVLVGEFVRGNASFVRPPAKEGWSNAFYDSCVNS 654

Query: 315 TWNPKIFVVFDANQIYPEYLIDF 337
             +P IFV+F+ +Q+YPEY+I +
Sbjct: 655 VSDPSIFVIFEKHQVYPEYVIQY 677


>gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens]
          Length = 902

 Score =  148 bits (374), Expect = 6e-36
 Identities = 93/324 (28%), Positives = 163/324 (50%), Gaps = 53/324 (16%)

Query: 32  TQWGWFYLAECGKWHMF--QPDTNSQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFA 89
           T+W W++  E G W  +  + D     +V S  +E  +++ P G + F     +Y++ F 
Sbjct: 605 TKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYELSFQ 664

Query: 90  EMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIP--MPPHWENVN-------------- 133
            M Q N+ +  Q+ + R P  +  + Y+ + +  P   P    +V+              
Sbjct: 665 GMIQTNIASKTQKDVIRRPTFVPQW-YVQQMKRGPDHQPAKTSSVSLTATFRPQEDFCFL 723

Query: 134 TQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRG 193
           +   Y+L  +H+   EY  V+  F  +M   +I++I++I+N +L + F  KK+Q+K++  
Sbjct: 724 SSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQMKEEG- 782

Query: 194 VPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYSSRFCKDDIK 253
                 ++LF+ TS  +VE+IC +NFD  ++  H   +GKG YFA+DA YS + C  D K
Sbjct: 783 ------KLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNCPYDAK 836

Query: 254 HGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVD 313
           +                      MF+A+VL+G +  G+  Y  PP +       +DSCVD
Sbjct: 837 N--------------------VVMFVAQVLVGKFTEGNITYTSPPPQ-------FDSCVD 869

Query: 314 DTWNPKIFVVFDANQIYPEYLIDF 337
              NP +FV+F  +Q+YP+Y+I++
Sbjct: 870 TRSNPSVFVIFQKDQVYPQYVIEY 893


>gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo
           sapiens]
          Length = 657

 Score =  138 bits (347), Expect = 8e-33
 Identities = 84/218 (38%), Positives = 119/218 (54%), Gaps = 25/218 (11%)

Query: 126 PPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMD--RNRIKRIQRIQNLDLWEFFCR 183
           P  W  ++    +  +P+  +   Y  + NLF KT+   + RI +I R+QN  LWE + R
Sbjct: 450 PETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKR 509

Query: 184 KKAQLKKKRGVPQ--INEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDA 241
           KK  + +K       INE+ LFHGTS + V+ IC HNFD R+ G H  +FG+G+YFA+ A
Sbjct: 510 KKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKA 569

Query: 242 AYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKD 301
           +YS  F K   K        GV             MFLA+VL G Y  G     RPP  +
Sbjct: 570 SYSHNFSKKSSK--------GVHF-----------MFLAKVLTGRYTMGSHGMRRPPPVN 610

Query: 302 GSYV--NLYDSCVDDTWNPKIFVVFDANQIYPEYLIDF 337
              V  +LYDSCVD+ + P+IFV+F+ +Q YP ++I +
Sbjct: 611 PGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQY 648


>gi|22749259 poly (ADP-ribose) polymerase family, member 15 isoform
           2 [Homo sapiens]
          Length = 444

 Score =  123 bits (309), Expect = 2e-28
 Identities = 77/216 (35%), Positives = 119/216 (55%), Gaps = 24/216 (11%)

Query: 125 MPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRK 184
           +P HW ++N Q+ + ++ L     EYN + + F +T     I++I+RIQN  LW+ +  K
Sbjct: 248 LPEHWTDMNHQL-FCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVK 306

Query: 185 KAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYS 244
           K Q+  K      NE++LFHGT ++ V  +  H F+    G +   +GKGTYFA DA+YS
Sbjct: 307 KRQMDIKNDHKN-NERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYS 365

Query: 245 SR--FCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKD- 301
           ++  + K D  +G                   K M++ RVL G +  G +  + PP K+ 
Sbjct: 366 AKDTYSKPD-SNGR------------------KHMYVVRVLTGVFTKGRAGLVTPPPKNP 406

Query: 302 GSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDF 337
            +  +L+DS  ++T +PK+FVVF  NQ YPEYLI F
Sbjct: 407 HNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITF 442


>gi|165377137 poly (ADP-ribose) polymerase family, member 15 isoform
           1 [Homo sapiens]
          Length = 678

 Score =  123 bits (309), Expect = 2e-28
 Identities = 77/216 (35%), Positives = 119/216 (55%), Gaps = 24/216 (11%)

Query: 125 MPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRK 184
           +P HW ++N Q+ + ++ L     EYN + + F +T     I++I+RIQN  LW+ +  K
Sbjct: 482 LPEHWTDMNHQL-FCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVK 540

Query: 185 KAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYS 244
           K Q+  K      NE++LFHGT ++ V  +  H F+    G +   +GKGTYFA DA+YS
Sbjct: 541 KRQMDIKNDHKN-NERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYS 599

Query: 245 SR--FCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKD- 301
           ++  + K D  +G                   K M++ RVL G +  G +  + PP K+ 
Sbjct: 600 AKDTYSKPD-SNGR------------------KHMYVVRVLTGVFTKGRAGLVTPPPKNP 640

Query: 302 GSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDF 337
            +  +L+DS  ++T +PK+FVVF  NQ YPEYLI F
Sbjct: 641 HNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITF 676


>gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Homo
            sapiens]
          Length = 1801

 Score =  117 bits (293), Expect = 1e-26
 Identities = 74/216 (34%), Positives = 110/216 (50%), Gaps = 20/216 (9%)

Query: 123  IPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFC 182
            + +P HW ++  Q  + ++ L     EYN VA+ F +T    RI++I+RIQN DLW  + 
Sbjct: 1603 VDIPAHWSDMKQQ-NFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQ 1661

Query: 183  RKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAA 242
             KK  +  K G   +NE+ LFHGT +  V  +  + F+    G +   +GKGTYFA +A 
Sbjct: 1662 AKKKTMDAKNG-QTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNAN 1720

Query: 243  YSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKD- 301
            YS+                      R      K ++  RVL G Y +G+   + PPSK+ 
Sbjct: 1721 YSAN-----------------DTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNP 1763

Query: 302  GSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDF 337
             +  +LYD+  D+  +P +FV F   Q YPEYLI F
Sbjct: 1764 QNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITF 1799


>gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Homo
            sapiens]
          Length = 1025

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 68/204 (33%), Positives = 99/204 (48%), Gaps = 35/204 (17%)

Query: 143  LHNQTHEYNEVANLFGKTMDRNR----IKRIQRIQNLDL---WEFFCRKKAQLKKKRGVP 195
            L   T E+ EV   F  T+D  R    + R++R+ +  L   +E +  +  Q  ++R V 
Sbjct: 823  LAENTGEFQEVVRAFYDTLDAARSSIRVVRVERVSHPLLQQQYELYRERLLQRCERRPV- 881

Query: 196  QINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYSSRFCKDDIKHG 255
               EQ+L+HGT++  V  IC H F+    G +  V+GKG YFAR A+             
Sbjct: 882  ---EQVLYHGTTAPAVPDICAHGFNRSFCGRNATVYGKGVYFARRAS------------- 925

Query: 256  NTFQIHGVSLQQRHL---FRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNL-YDSC 311
                   +S+Q R+       +K++F+ARVL GDY  G      PP +   +V L YDS 
Sbjct: 926  -------LSVQDRYSPPNADGHKAVFVARVLTGDYGQGRRGLRAPPLRGPGHVLLRYDSA 978

Query: 312  VDDTWNPKIFVVFDANQIYPEYLI 335
            VD    P IFV+F   Q  P +LI
Sbjct: 979  VDCICQPSIFVIFHDTQALPTHLI 1002


>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
            polymerase 2 [Homo sapiens]
          Length = 1166

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 52/187 (27%), Positives = 85/187 (45%), Gaps = 24/187 (12%)

Query: 158  GKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIH 217
            G   +R  I +IQ++ N  LWE +  ++ ++ ++      NE+MLFHG  S FV AI   
Sbjct: 986  GGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENH-NHANERMLFHG--SPFVNAIIHK 1042

Query: 218  NFDWRINGIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSM 277
             FD R +   G +FG G YFA +++ S+++    I  G    +H    + R  +  ++ +
Sbjct: 1043 GFDER-HAYIGGMFGAGIYFAENSSKSNQYVY-GIGGGTGCPVH----KDRSCYICHRQL 1096

Query: 278  FLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKI-------FVVFDANQIY 330
               RV +G      S      S  G +          T  P +       +V++   Q Y
Sbjct: 1097 LFCRVTLGKSFLQFSAMKMAHSPPGHH--------SVTGRPSVNGLALAEYVIYRGEQAY 1148

Query: 331  PEYLIDF 337
            PEYLI +
Sbjct: 1149 PEYLITY 1155


>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
            polymerase [Homo sapiens]
          Length = 1327

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 10/180 (5%)

Query: 158  GKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIH 217
            G   +R  + RIQ++ N  L E FC ++ ++ ++      NE+MLFHG  S F+ AI   
Sbjct: 1139 GGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENH-NHHNERMLFHG--SPFINAIIHK 1195

Query: 218  NFDWRINGIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSM 277
             FD R +   G +FG G YFA +++ S+++    I  G     H    + R  +  ++ M
Sbjct: 1196 GFDER-HAYIGGMFGAGIYFAENSSKSNQYVY-GIGGGTGCPTH----KDRSCYICHRQM 1249

Query: 278  FLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDF 337
               RV +G      S      +  G +  +    V+     + +V++   Q YPEYLI +
Sbjct: 1250 LFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAE-YVIYRGEQAYPEYLITY 1308


>gi|226371716 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 18/170 (10%)

Query: 165 RIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRIN 224
           ++ ++++I N  L   F RKK  +++K     ++ + LF     +F   +C   F    +
Sbjct: 632 QVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHR-LFQQVPYQFCNVVCRVGFQRMYS 690

Query: 225 GIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLI 284
                 +G G YF ++    +   K             +S   + ++     +F A VL 
Sbjct: 691 TPCDPKYGAGIYFTKNLKNLAEKAKK------------ISAADKLIY-----VFEAEVLT 733

Query: 285 GDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYL 334
           G +  G    + PP      ++ +DS VD+  +P+ FV+F   Q  P+YL
Sbjct: 734 GFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYL 783


>gi|226371714 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 18/170 (10%)

Query: 165 RIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRIN 224
           ++ ++++I N  L   F RKK  +++K     ++ + LF     +F   +C   F    +
Sbjct: 632 QVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHR-LFQQVPYQFCNVVCRVGFQRMYS 690

Query: 225 GIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLI 284
                 +G G YF ++    +   K             +S   + ++     +F A VL 
Sbjct: 691 TPCDPKYGAGIYFTKNLKNLAEKAKK------------ISAADKLIY-----VFEAEVLT 733

Query: 285 GDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYL 334
           G +  G    + PP      ++ +DS VD+  +P+ FV+F   Q  P+YL
Sbjct: 734 GFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYL 783


>gi|226371712 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 18/170 (10%)

Query: 165 RIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRIN 224
           ++ ++++I N  L   F RKK  +++K     ++ + LF     +F   +C   F    +
Sbjct: 632 QVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHR-LFQQVPYQFCNVVCRVGFQRMYS 690

Query: 225 GIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLI 284
                 +G G YF ++    +   K             +S   + ++     +F A VL 
Sbjct: 691 TPCDPKYGAGIYFTKNLKNLAEKAKK------------ISAADKLIY-----VFEAEVLT 733

Query: 285 GDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYL 334
           G +  G    + PP      ++ +DS VD+  +P+ FV+F   Q  P+YL
Sbjct: 734 GFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYL 783


>gi|226371710 poly (ADP-ribose) polymerase family, member 9 isoform
           a [Homo sapiens]
          Length = 854

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 18/170 (10%)

Query: 165 RIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRIN 224
           ++ ++++I N  L   F RKK  +++K     ++ + LF     +F   +C   F    +
Sbjct: 667 QVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHR-LFQQVPYQFCNVVCRVGFQRMYS 725

Query: 225 GIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLI 284
                 +G G YF ++    +   K             +S   + ++     +F A VL 
Sbjct: 726 TPCDPKYGAGIYFTKNLKNLAEKAKK------------ISAADKLIY-----VFEAEVLT 768

Query: 285 GDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYL 334
           G +  G    + PP      ++ +DS VD+  +P+ FV+F   Q  P+YL
Sbjct: 769 GFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYL 818


>gi|226371706 poly (ADP-ribose) polymerase family, member 9 isoform
           a [Homo sapiens]
          Length = 854

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 18/170 (10%)

Query: 165 RIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRIN 224
           ++ ++++I N  L   F RKK  +++K     ++ + LF     +F   +C   F    +
Sbjct: 667 QVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHR-LFQQVPYQFCNVVCRVGFQRMYS 725

Query: 225 GIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLI 284
                 +G G YF ++    +   K             +S   + ++     +F A VL 
Sbjct: 726 TPCDPKYGAGIYFTKNLKNLAEKAKK------------ISAADKLIY-----VFEAEVLT 768

Query: 285 GDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYL 334
           G +  G    + PP      ++ +DS VD+  +P+ FV+F   Q  P+YL
Sbjct: 769 GFFCQGHPLNIVPPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYL 818


>gi|27477138 zinc finger antiviral protein isoform 2 [Homo sapiens]
          Length = 699

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 32  TQWGWFYLAECGKWHMF--QPDTNSQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFA 89
           T+W W++  E G W  +  + D     +V S  +E  +++ P G + F     +Y++ F 
Sbjct: 605 TKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYELSFQ 664

Query: 90  EMKQMNLTTGKQRLIKRAP 108
            M Q N+ +  Q+ + R P
Sbjct: 665 GMIQTNIASKTQKDVIRRP 683


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 36.2 bits (82), Expect = 0.043
 Identities = 23/94 (24%), Positives = 40/94 (42%), Gaps = 9/94 (9%)

Query: 9    FHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSSEDIEKSFK 68
            F++   + SK        + ++   W WF     G+W  +    NS        I+ ++K
Sbjct: 1592 FYEKTAISSKRRAQMTKYLQSNSNNWRWFD-DRSGRWCSYSASNNST-------IDSAWK 1643

Query: 69   TNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQR 102
            +    S+ FT  +  Y + F  M Q+N  TG +R
Sbjct: 1644 SGET-SVRFTAGRRRYTVQFTTMVQVNEETGNRR 1676


>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform
           b [Homo sapiens]
          Length = 533

 Score = 33.9 bits (76), Expect = 0.21
 Identities = 41/162 (25%), Positives = 66/162 (40%), Gaps = 26/162 (16%)

Query: 139 QLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQIN 198
           QL  L +   EY  +     +T   +R   +Q I  ++  +     + Q   K G    N
Sbjct: 325 QLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWKVN--QEGEEDRFQAHSKLG----N 378

Query: 199 EQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTF 258
            ++L+HGT+   V AI       RI    G   GKG YFA + + S+ +           
Sbjct: 379 RKLLWHGTNMAVVAAILTSGL--RIMPHSGGRVGKGIYFASENSKSAGY----------- 425

Query: 259 QIHGVSLQQRHLFRTYKSMFLARVLIG--DYINGDSKYMRPP 298
            + G+     H+      MFL  V +G   +IN D+  ++ P
Sbjct: 426 -VIGMKCGAHHV----GYMFLGEVALGREHHINTDNPSLKSP 462


>gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform
           a [Homo sapiens]
          Length = 540

 Score = 33.9 bits (76), Expect = 0.21
 Identities = 41/162 (25%), Positives = 66/162 (40%), Gaps = 26/162 (16%)

Query: 139 QLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQIN 198
           QL  L +   EY  +     +T   +R   +Q I  ++  +     + Q   K G    N
Sbjct: 332 QLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWKVN--QEGEEDRFQAHSKLG----N 385

Query: 199 EQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTF 258
            ++L+HGT+   V AI       RI    G   GKG YFA + + S+ +           
Sbjct: 386 RKLLWHGTNMAVVAAILTSGL--RIMPHSGGRVGKGIYFASENSKSAGY----------- 432

Query: 259 QIHGVSLQQRHLFRTYKSMFLARVLIG--DYINGDSKYMRPP 298
            + G+     H+      MFL  V +G   +IN D+  ++ P
Sbjct: 433 -VIGMKCGAHHV----GYMFLGEVALGREHHINTDNPSLKSP 469


>gi|20270349 MIT, microtubule interacting and transport, domain
           containing 1 [Homo sapiens]
          Length = 249

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 4/99 (4%)

Query: 166 IKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRING 225
           IKR  +++ + L         Q+++ RG+ +I E +  HG   E   +  IH+ + R N 
Sbjct: 142 IKRPCKVKTIHLLTSLDEGIEQVQQSRGLQEIEESLRSHGVLLEVQYSSSIHDREIRFNN 201

Query: 226 IHGAVFGKG-TYFAR-DAAYSSRFCKDDIK--HGNTFQI 260
                 G+G  YF +  + +S  +C  D++  H  T  I
Sbjct: 202 GWMIKIGRGLDYFKKPQSRFSLGYCDFDLRPCHETTVDI 240


>gi|21389569 tektin 5 [Homo sapiens]
          Length = 485

 Score = 32.7 bits (73), Expect = 0.47
 Identities = 43/205 (20%), Positives = 82/205 (40%), Gaps = 32/205 (15%)

Query: 75  ISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIPMPPHWENVNT 134
           I F  S+ SY++D    +  NL T K+RL   A                        VN 
Sbjct: 148 IGFWKSELSYELDRLLTENQNLETVKRRLECAA----------------------NEVNC 185

Query: 135 QVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQ--NLDLWEFFCRKKAQLKKKR 192
            +   L  L+++        +L    +++N I+ +  ++     + +   R   Q++  R
Sbjct: 186 PLQVALECLYHREKRIG--IDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNR 243

Query: 193 GVPQINEQMLFHGTSSEFVEAIC--IHNFDWRINGIHGAVFGKGTYFARDAAYSSRFCKD 250
               + E+ L   +S++ ++  C  + N    I+  HG     GT    +    ++F  D
Sbjct: 244 DAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETW--AKFSND 301

Query: 251 DIKHGNTFQIHGVSLQQ--RHLFRT 273
           +IKH    + + + L++   HLF T
Sbjct: 302 NIKHSQNMRANSIQLREEAEHLFET 326


>gi|110825963 poly (ADP-ribose) polymerase family, member 2 isoform
           2 [Homo sapiens]
          Length = 570

 Score = 32.0 bits (71), Expect = 0.81
 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 15/129 (11%)

Query: 124 PMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCR 183
           P+  H+ N++      L PL ++++E+  ++     T           +  LDL+E    
Sbjct: 344 PLDQHYRNLHCA----LRPLDHESYEFKVISQYLQSTHAPTHSDYTMTL--LDLFEV--- 394

Query: 184 KKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRING----IHGAVFGKGTYFAR 239
           +K   K+       N  +L+HG+       I  H    RI      I G +FGKG YFA 
Sbjct: 395 EKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGL--RIAPPEAPITGYMFGKGIYFAD 452

Query: 240 DAAYSSRFC 248
            ++ S+ +C
Sbjct: 453 MSSKSANYC 461


>gi|110825961 poly (ADP-ribose) polymerase family, member 2 isoform
           1 [Homo sapiens]
          Length = 583

 Score = 32.0 bits (71), Expect = 0.81
 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 15/129 (11%)

Query: 124 PMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCR 183
           P+  H+ N++      L PL ++++E+  ++     T           +  LDL+E    
Sbjct: 357 PLDQHYRNLHCA----LRPLDHESYEFKVISQYLQSTHAPTHSDYTMTL--LDLFEV--- 407

Query: 184 KKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRING----IHGAVFGKGTYFAR 239
           +K   K+       N  +L+HG+       I  H    RI      I G +FGKG YFA 
Sbjct: 408 EKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGL--RIAPPEAPITGYMFGKGIYFAD 465

Query: 240 DAAYSSRFC 248
            ++ S+ +C
Sbjct: 466 MSSKSANYC 474


>gi|148237498 deltex 4 homolog [Homo sapiens]
          Length = 619

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 15/32 (46%), Positives = 20/32 (62%)

Query: 75  ISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKR 106
           I  T+  FSY IDF  M Q+N  T +QR ++R
Sbjct: 124 IDLTSIGFSYVIDFNTMGQINRQTQRQRRVRR 155


>gi|56550051 ubiquitin specific protease 39 [Homo sapiens]
          Length = 565

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 112 SAFSYICENEAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQR 171
           S F Y+  +  +P  P +++   Q+    +PL N   ++N +     KT   N +KR Q 
Sbjct: 386 STFMYLTLD--LPTAPLYKDEKEQLIIPQVPLFNILAKFNGITEKEYKTYKENFLKRFQ- 442

Query: 172 IQNLDLWEFFCRKK 185
           +  L  +  FC K+
Sbjct: 443 LTKLPPYLIFCIKR 456


>gi|118600963 Nik related kinase [Homo sapiens]
          Length = 1582

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 12/35 (34%), Positives = 21/35 (60%), Gaps = 1/35 (2%)

Query: 279 LARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVD 313
           L+ +   D++   +  ++PP +DG YV LYD+  D
Sbjct: 896 LSEIFRNDWLT-PAPVIQPPEEDGDYVELYDASAD 929


>gi|209977117 unc-5 homolog D [Homo sapiens]
          Length = 953

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 15/63 (23%), Positives = 26/63 (41%), Gaps = 5/63 (7%)

Query: 11  KAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSSEDIEKSFKTN 70
           K  E+F   T  +V+D    +  W      +C  W       + + SV    + K+F+ +
Sbjct: 110 KVREVFINVTRQQVEDFHGPEDYW-----CQCVAWSHLGTSKSRKASVRIAYLRKNFEQD 164

Query: 71  PCG 73
           P G
Sbjct: 165 PQG 167


>gi|148612805 pigeon homolog [Homo sapiens]
          Length = 854

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 10/26 (38%), Positives = 17/26 (65%)

Query: 123 IPMPPHWENVNTQVPYQLIPLHNQTH 148
           +P+PP +  ++T +  Q +PLHN  H
Sbjct: 692 LPLPPGFHTLHTILGVQCLPLHNLLH 717


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,082,953
Number of Sequences: 37866
Number of extensions: 541932
Number of successful extensions: 1199
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1150
Number of HSP's gapped (non-prelim): 32
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.