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Search of human proteins with 194306650
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194306650 SET domain and mariner transposase fusion [Homo
sapiens]
(684 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194306650 SET domain and mariner transposase fusion [Homo sap... 1435 0.0
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 140 5e-33
gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens] 139 7e-33
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 139 7e-33
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 139 7e-33
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens] 130 4e-30
gi|197313748 SET domain containing 2 [Homo sapiens] 100 8e-21
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 91 4e-18
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 89 1e-17
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 86 9e-17
gi|19923586 nuclear receptor binding SET domain protein 1 isofor... 86 9e-17
gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens] 84 4e-16
gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens] 84 4e-16
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 83 7e-16
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 83 7e-16
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 83 7e-16
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 83 7e-16
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 81 3e-15
gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens] 75 2e-13
gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens] 75 2e-13
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 73 8e-13
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 73 8e-13
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 73 1e-12
gi|55741677 SET domain containing 1A [Homo sapiens] 69 2e-11
gi|210032580 SET domain containing 1B [Homo sapiens] 66 9e-11
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 65 2e-10
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 58 3e-08
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 53 1e-06
gi|45356743 SET domain-containing 8 [Homo sapiens] 50 7e-06
gi|122937492 SET domain containing 5 [Homo sapiens] 44 6e-04
>gi|194306650 SET domain and mariner transposase fusion [Homo
sapiens]
Length = 684
Score = 1435 bits (3715), Expect = 0.0
Identities = 684/684 (100%), Positives = 684/684 (100%)
Query: 1 MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVG 60
MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVG
Sbjct: 1 MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVG 60
Query: 61 PGADIDPTQITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNV 120
PGADIDPTQITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNV
Sbjct: 61 PGADIDPTQITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNV 120
Query: 121 LCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQR 180
LCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQR
Sbjct: 121 LCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQR 180
Query: 181 RIHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSM 240
RIHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSM
Sbjct: 181 RIHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSM 240
Query: 241 VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLPF 300
VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLPF
Sbjct: 241 VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLPF 300
Query: 301 DSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFK 360
DSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFK
Sbjct: 301 DSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFK 360
Query: 361 MGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAI 420
MGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAI
Sbjct: 361 MGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAI 420
Query: 421 IEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEVSSSLI 480
IEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEVSSSLI
Sbjct: 421 IEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEVSSSLI 480
Query: 481 LRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTIWWSAA 540
LRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTIWWSAA
Sbjct: 481 LRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTIWWSAA 540
Query: 541 GLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQ 600
GLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQ
Sbjct: 541 GLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQ 600
Query: 601 KLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVESQSTDF 660
KLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVESQSTDF
Sbjct: 601 KLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVESQSTDF 660
Query: 661 YATGINQLISRWQKCVDCNGSYFD 684
YATGINQLISRWQKCVDCNGSYFD
Sbjct: 661 YATGINQLISRWQKCVDCNGSYFD 684
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1 isoform
1 [Homo sapiens]
Length = 1298
Score = 140 bits (352), Expect = 5e-33
Identities = 95/288 (32%), Positives = 143/288 (49%), Gaps = 44/288 (15%)
Query: 23 APTEQL---DVACGQENLP---VGAWPPGAAPAPFQYTPDHVVGPGADIDPTQITFPGCI 76
+P E++ D+A G E +P V A P+ ++Y + V +ID C+
Sbjct: 1004 SPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCV 1063
Query: 77 CVKTPCLPGTCSCLRHGEN--YD-DNSCLRDIGSGGKYAEP--VFECNVLCRCSDHCRNR 131
C+ C C C + YD D L + AEP +FECN C C +CRNR
Sbjct: 1064 CIDD-CSSSNCMCGQLSMRCWYDKDGRLLPEFNM----AEPPLIFECNHACSCWRNCRNR 1118
Query: 132 VVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSN 191
VVQ GL+ Q+++T GWG+R+L+ IP G FVCEY GE++ SE + + +
Sbjct: 1119 VVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEA------DVREEDS 1172
Query: 192 YIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRI-----DSMVPKLAL 246
Y+ + +G+V +D + GN+ RF+NH CEPNL +PVR+ D P++A
Sbjct: 1173 YLFDLDNK--DGEVY--CIDARFYGNVSRFINHHCEPNL--VPVRVFMAHQDLRFPRIAF 1226
Query: 247 FAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSC 294
F+ + I E+L +DY R+ ++ GKL C CG+ C
Sbjct: 1227 FSTRLIEAGEQLGFDYGERFWDI----------KGKLFS-CRCGSPKC 1263
>gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]
Length = 412
Score = 139 bits (351), Expect = 7e-33
Identities = 89/270 (32%), Positives = 136/270 (50%), Gaps = 34/270 (12%)
Query: 48 PAPFQYTPDHVVGPGADIDPTQITFPGCICVKTP---CLPGTCSCLRHGENYDDNSCLRD 104
P F Y ++ VG G ++ + C+ P C PG H Y+D +R
Sbjct: 157 PRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPTGGCCPGASL---HKFAYNDQGQVRL 213
Query: 105 IGSGGKYAEPVFECNVLCRCSDHCRNRVVQKGLQFHFQVFKTHK-KGWGLRTLEFIPKGR 163
+ P++ECN CRC C NRVVQKG+++ +F+T +GWG+RTLE I K
Sbjct: 214 -----RAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNS 268
Query: 164 FVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIR--EHVYNGQVMETFVDPTYIGNIGRF 221
FV EY GE++ E +RR + + + Y+ + E VY VD Y GNI F
Sbjct: 269 FVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYT-------VDAAYYGNISHF 321
Query: 222 LNHSCEPNLLMIPVRIDSM---VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERL 278
+NHSC+PNL + V ID++ +P++A FA + I EEL++DY+ + + + +
Sbjct: 322 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS 381
Query: 279 DHG----------KLRKPCYCGAKSCTAFL 298
+ G ++R C CG +SC +L
Sbjct: 382 NFGLAGLPGSPKKRVRIECKCGTESCRKYL 411
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2 isoform
b [Homo sapiens]
Length = 1176
Score = 139 bits (351), Expect = 7e-33
Identities = 90/277 (32%), Positives = 136/277 (49%), Gaps = 37/277 (13%)
Query: 29 DVACGQENLP---VGAWPPGAAPAPFQYTPDHVVGPGADIDPTQITFPGCICVKTPCLPG 85
DVA G EN+P V P ++Y ++ +ID C CV C
Sbjct: 891 DVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDD-CSSS 949
Query: 86 TCSCLRHGEN--YDDNSCLRDIGSGGKYAEP-VFECNVLCRCSDHCRNRVVQKGLQFHFQ 142
C C + YD + L + K P +FECN C C +C+NRVVQ G++ Q
Sbjct: 950 NCLCGQLSIRCWYDKDGRL--LQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQ 1007
Query: 143 VFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIREHVYN 202
+++T K GWG+R L+ IP+G F+CEY GE++ +E + D +Y+ + +
Sbjct: 1008 LYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEA------DVREDDSYLFDLDNK--D 1059
Query: 203 GQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRI-----DSMVPKLALFAAKDIVPEEE 257
G+V +D Y GNI RF+NH C+PN+ IPVR+ D P++A F+++DI EE
Sbjct: 1060 GEVY--CIDARYYGNISRFINHLCDPNI--IPVRVFMLHQDLRFPRIAFFSSRDIRTGEE 1115
Query: 258 LSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSC 294
L +DY R+ ++ C CG++ C
Sbjct: 1116 LGFDYGDRFWDIK-----------SKYFTCQCGSEKC 1141
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2 isoform
a [Homo sapiens]
Length = 1210
Score = 139 bits (351), Expect = 7e-33
Identities = 90/277 (32%), Positives = 136/277 (49%), Gaps = 37/277 (13%)
Query: 29 DVACGQENLP---VGAWPPGAAPAPFQYTPDHVVGPGADIDPTQITFPGCICVKTPCLPG 85
DVA G EN+P V P ++Y ++ +ID C CV C
Sbjct: 925 DVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDD-CSSS 983
Query: 86 TCSCLRHGEN--YDDNSCLRDIGSGGKYAEP-VFECNVLCRCSDHCRNRVVQKGLQFHFQ 142
C C + YD + L + K P +FECN C C +C+NRVVQ G++ Q
Sbjct: 984 NCLCGQLSIRCWYDKDGRL--LQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQ 1041
Query: 143 VFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIREHVYN 202
+++T K GWG+R L+ IP+G F+CEY GE++ +E + D +Y+ + +
Sbjct: 1042 LYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEA------DVREDDSYLFDLDNK--D 1093
Query: 203 GQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRI-----DSMVPKLALFAAKDIVPEEE 257
G+V +D Y GNI RF+NH C+PN+ IPVR+ D P++A F+++DI EE
Sbjct: 1094 GEVY--CIDARYYGNISRFINHLCDPNI--IPVRVFMLHQDLRFPRIAFFSSRDIRTGEE 1149
Query: 258 LSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSC 294
L +DY R+ ++ C CG++ C
Sbjct: 1150 LGFDYGDRFWDIK-----------SKYFTCQCGSEKC 1175
>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
Length = 350
Score = 130 bits (327), Expect = 4e-30
Identities = 88/261 (33%), Positives = 134/261 (51%), Gaps = 27/261 (10%)
Query: 48 PAPFQYTPDHVVGPGADIDPTQITFPGCICVKTPCLPGTCSCLRHGE--NYDDNSCLRDI 105
P+ F Y ++ PG + + TF GC C T C C G Y+ N ++ I
Sbjct: 106 PSDFYYINEYKPAPGISL-VNEATF-GCSC--TDCFFQKCCPAEAGVLLAYNKNQQIK-I 160
Query: 106 GSGGKYAEPVFECNVLCRCSDHCRNRVVQKGLQFHFQVFKT-HKKGWGLRTLEFIPKGRF 164
G P++ECN C+C C NR+VQKG Q+ +F+T + +GWG++TL I + F
Sbjct: 161 PPG----TPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSF 216
Query: 165 VCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNH 224
V EY GEV+ E +RR Y+ + + + E VD GN+ F+NH
Sbjct: 217 VMEYVGEVITSEEAERRGQFYDNKGITYLFDL-----DYESDEFTVDAARYGNVSHFVNH 271
Query: 225 SCEPNLLMIPVRIDSM---VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHG 281
SC+PNL + V ID++ +P++ALF+ + I EEL++DY + +S D +DH
Sbjct: 272 SCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDS--IDHS 328
Query: 282 ----KLRKPCYCGAKSCTAFL 298
++R C CGA +C +L
Sbjct: 329 PAKKRVRTVCKCGAVTCRGYL 349
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 99.8 bits (247), Expect = 8e-21
Identities = 57/186 (30%), Positives = 90/186 (48%), Gaps = 24/186 (12%)
Query: 115 VFECNVLCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLG 174
+ EC+ C D+C NR Q+ +V T KKGWGLR + +P FV EY GEVL
Sbjct: 1526 MIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLD 1585
Query: 175 FSEVQRRI--HLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLM 232
E + R+ + + K+ Y +A++ + +D T GN RF+NHSCEPN
Sbjct: 1586 HKEFKARVKEYARNKNIHYYFMALKN--------DEIIDATQKGNCSRFMNHSCEPNCET 1637
Query: 233 IPVRIDSMVPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAK 292
++ + ++ F K + EL++DY + +GK + C+CG+
Sbjct: 1638 QKWTVNGQL-RVGFFTTKLVPSGSELTFDYQFQ-------------RYGKEAQKCFCGSA 1683
Query: 293 SCTAFL 298
+C +L
Sbjct: 1684 NCRGYL 1689
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 90.9 bits (224), Expect = 4e-18
Identities = 61/186 (32%), Positives = 92/186 (49%), Gaps = 25/186 (13%)
Query: 116 FECNV-LCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLG 174
+EC+ +C D C+N+ K L ++ KT ++GWGLRT I KG FV EY GE++
Sbjct: 1121 YECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELID 1180
Query: 175 FSEVQRRI-HLQTKSDSN-YIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLM 232
E + RI S +N Y++ + + + +D GN RF+NHSC PN
Sbjct: 1181 EEECRLRIKRAHENSVTNFYMLTVTK--------DRIIDAGPKGNYSRFMNHSCNPNCET 1232
Query: 233 IPVRIDSMVPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAK 292
++ V ++ LFA DI EL+++Y+ L G R C+CGA
Sbjct: 1233 QKWTVNGDV-RVGLFALCDIPAGMELTFNYNLDCL-------------GNGRTECHCGAD 1278
Query: 293 SCTAFL 298
+C+ FL
Sbjct: 1279 NCSGFL 1284
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 89.0 bits (219), Expect = 1e-17
Identities = 62/215 (28%), Positives = 111/215 (51%), Gaps = 27/215 (12%)
Query: 86 TCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNV-LCRCSDHCRNRVVQKGLQFH-FQV 143
TC+C + ++ C+ D + +AE C+ C C + C N+ +Q+ +
Sbjct: 2090 TCNCKKPDDD-TRKGCVDDCLNRMIFAE----CSPNTCPCGEQCCNQRIQRHEWVQCLER 2144
Query: 144 FKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIREHVYNG 203
F+ +KGWG+RT E + G+F+ EY GEV+ E + R+ Q + S++ ++ +G
Sbjct: 2145 FRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCL---NLDSG 2201
Query: 204 QVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDYS 263
V++++ +GN RF+NHSC+PN M ++ V ++ L+A KD+ EL+YDY+
Sbjct: 2202 MVIDSY----RMGNEARFINHSCDPNCEMQKWSVNG-VYRIGLYALKDMPAGTELTYDYN 2256
Query: 264 GRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
N+ +K++L C CG + C +
Sbjct: 2257 FHSFNV----EKQQL--------CKCGFEKCRGII 2279
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 86.3 bits (212), Expect = 9e-17
Identities = 57/186 (30%), Positives = 91/186 (48%), Gaps = 23/186 (12%)
Query: 115 VFECN-VLCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVL 173
++EC+ +C C+N+ K ++F+T ++GWGLRT I KG FV EY GE++
Sbjct: 1648 LYECHPTVCPAGGRCQNQCFSKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELI 1707
Query: 174 GFSEVQRRIHLQTKSD-SNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLM 232
E + RI + D +N+ + + + +D GN RF+NH C+PN
Sbjct: 1708 DEEECRARIRYAQEHDITNFYMLTLD-------KDRIIDAGPKGNYARFMNHCCQPNCET 1760
Query: 233 IPVRIDSMVPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAK 292
++ ++ LFA DI EL+++Y + E L +GK C CGA
Sbjct: 1761 QKWSVNGDT-RVGLFALSDIKAGTELTFNY-----------NLECLGNGK--TVCKCGAP 1806
Query: 293 SCTAFL 298
+C+ FL
Sbjct: 1807 NCSGFL 1812
>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
[Homo sapiens]
Length = 2696
Score = 86.3 bits (212), Expect = 9e-17
Identities = 57/186 (30%), Positives = 91/186 (48%), Gaps = 23/186 (12%)
Query: 115 VFECN-VLCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVL 173
++EC+ +C C+N+ K ++F+T ++GWGLRT I KG FV EY GE++
Sbjct: 1917 LYECHPTVCPAGGRCQNQCFSKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELI 1976
Query: 174 GFSEVQRRIHLQTKSD-SNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLM 232
E + RI + D +N+ + + + +D GN RF+NH C+PN
Sbjct: 1977 DEEECRARIRYAQEHDITNFYMLTLD-------KDRIIDAGPKGNYARFMNHCCQPNCET 2029
Query: 233 IPVRIDSMVPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAK 292
++ ++ LFA DI EL+++Y + E L +GK C CGA
Sbjct: 2030 QKWSVNGDT-RVGLFALSDIKAGTELTFNY-----------NLECLGNGK--TVCKCGAP 2075
Query: 293 SCTAFL 298
+C+ FL
Sbjct: 2076 NCSGFL 2081
>gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens]
Length = 1290
Score = 84.0 bits (206), Expect = 4e-16
Identities = 55/160 (34%), Positives = 77/160 (48%), Gaps = 16/160 (10%)
Query: 28 LDVACGQENLPVGAWPPGAAPAPFQ--YTPDHVVGPGADIDPTQITFPGCICVKTPCLPG 85
LD+ G+E++P+ P Q Y+ + + G G I+ GC C
Sbjct: 680 LDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKS 739
Query: 86 TCSCLRHGENYDDNSCLR----DIGSGGKYAE-------PVFECNVLCRCSDH-CRNRVV 133
C+C H +C + SG +Y V+ECN C+C + C NR+V
Sbjct: 740 KCAC--HQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLV 797
Query: 134 QKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVL 173
Q GLQ Q+FKT KGWG+R L+ I KG FVC YAG++L
Sbjct: 798 QHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKIL 837
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/97 (37%), Positives = 50/97 (51%), Gaps = 15/97 (15%)
Query: 201 YNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDS---MVPKLALFAAKDIVPEEE 257
Y+G+ +D GN+GR+LNHSC PNL + V +D+ P +A FA+K I E
Sbjct: 1201 YDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASK-IRAGTE 1259
Query: 258 LSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSC 294
L++DY+ + E KE L C CGA C
Sbjct: 1260 LTWDYN---YEVGSVEGKELL--------CCCGAIEC 1285
>gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens]
Length = 1291
Score = 84.0 bits (206), Expect = 4e-16
Identities = 55/160 (34%), Positives = 77/160 (48%), Gaps = 16/160 (10%)
Query: 28 LDVACGQENLPVGAWPPGAAPAPFQ--YTPDHVVGPGADIDPTQITFPGCICVKTPCLPG 85
LD+ G+E++P+ P Q Y+ + + G G I+ GC C
Sbjct: 680 LDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKS 739
Query: 86 TCSCLRHGENYDDNSCLR----DIGSGGKYAE-------PVFECNVLCRCSDH-CRNRVV 133
C+C H +C + SG +Y V+ECN C+C + C NR+V
Sbjct: 740 KCAC--HQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLV 797
Query: 134 QKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVL 173
Q GLQ Q+FKT KGWG+R L+ I KG FVC YAG++L
Sbjct: 798 QHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKIL 837
Score = 55.5 bits (132), Expect = 2e-07
Identities = 36/97 (37%), Positives = 50/97 (51%), Gaps = 14/97 (14%)
Query: 201 YNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDS---MVPKLALFAAKDIVPEEE 257
Y+G+ +D GN+GR+LNHSC PNL + V +D+ P +A FA+K I E
Sbjct: 1201 YDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTE 1260
Query: 258 LSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSC 294
L++DY+ + E KE L C CGA C
Sbjct: 1261 LTWDYN---YEVGSVEGKELL--------CCCGAIEC 1286
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 83.2 bits (204), Expect = 7e-16
Identities = 64/217 (29%), Positives = 98/217 (45%), Gaps = 35/217 (16%)
Query: 87 CSCLRHGENYD--DNSCLRDIGSGGKYAEPVFECNV-LCRCSDHCRNRVVQKGLQFHFQV 143
C+C EN D+ CL + +FEC+ +C + C+N+ K ++
Sbjct: 1016 CNCKPTDENPCGFDSECLNRM--------LMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
Query: 144 FKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSN--YIIAIREHVY 201
KT KGWGL I KG FV EY GE++ E RI ++D Y++ I +
Sbjct: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDK--- 1124
Query: 202 NGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYD 261
+ +D GN RF+NHSC+PN + ++ ++ LFA DI EL+++
Sbjct: 1125 -----DRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDT-RVGLFAVCDIPAGTELTFN 1178
Query: 262 YSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
Y+ L G + C CGA +C+ FL
Sbjct: 1179 YNLDCL-------------GNEKTVCRCGASNCSGFL 1202
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 83.2 bits (204), Expect = 7e-16
Identities = 64/217 (29%), Positives = 98/217 (45%), Gaps = 35/217 (16%)
Query: 87 CSCLRHGENYD--DNSCLRDIGSGGKYAEPVFECNV-LCRCSDHCRNRVVQKGLQFHFQV 143
C+C EN D+ CL + +FEC+ +C + C+N+ K ++
Sbjct: 1016 CNCKPTDENPCGFDSECLNRM--------LMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
Query: 144 FKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSN--YIIAIREHVY 201
KT KGWGL I KG FV EY GE++ E RI ++D Y++ I +
Sbjct: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDK--- 1124
Query: 202 NGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYD 261
+ +D GN RF+NHSC+PN + ++ ++ LFA DI EL+++
Sbjct: 1125 -----DRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDT-RVGLFAVCDIPAGTELTFN 1178
Query: 262 YSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
Y+ L G + C CGA +C+ FL
Sbjct: 1179 YNLDCL-------------GNEKTVCRCGASNCSGFL 1202
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 83.2 bits (204), Expect = 7e-16
Identities = 64/217 (29%), Positives = 98/217 (45%), Gaps = 35/217 (16%)
Query: 87 CSCLRHGENYD--DNSCLRDIGSGGKYAEPVFECNV-LCRCSDHCRNRVVQKGLQFHFQV 143
C+C EN D+ CL + +FEC+ +C + C+N+ K ++
Sbjct: 1016 CNCKPTDENPCGFDSECLNRM--------LMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
Query: 144 FKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSN--YIIAIREHVY 201
KT KGWGL I KG FV EY GE++ E RI ++D Y++ I +
Sbjct: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDK--- 1124
Query: 202 NGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYD 261
+ +D GN RF+NHSC+PN + ++ ++ LFA DI EL+++
Sbjct: 1125 -----DRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDT-RVGLFAVCDIPAGTELTFN 1178
Query: 262 YSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
Y+ L G + C CGA +C+ FL
Sbjct: 1179 YNLDCL-------------GNEKTVCRCGASNCSGFL 1202
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 83.2 bits (204), Expect = 7e-16
Identities = 64/217 (29%), Positives = 98/217 (45%), Gaps = 35/217 (16%)
Query: 87 CSCLRHGENYD--DNSCLRDIGSGGKYAEPVFECNV-LCRCSDHCRNRVVQKGLQFHFQV 143
C+C EN D+ CL + +FEC+ +C + C+N+ K ++
Sbjct: 1016 CNCKPTDENPCGFDSECLNRM--------LMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
Query: 144 FKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSN--YIIAIREHVY 201
KT KGWGL I KG FV EY GE++ E RI ++D Y++ I +
Sbjct: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDK--- 1124
Query: 202 NGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYD 261
+ +D GN RF+NHSC+PN + ++ ++ LFA DI EL+++
Sbjct: 1125 -----DRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDT-RVGLFAVCDIPAGTELTFN 1178
Query: 262 YSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
Y+ L G + C CGA +C+ FL
Sbjct: 1179 YNLDCL-------------GNEKTVCRCGASNCSGFL 1202
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 81.3 bits (199), Expect = 3e-15
Identities = 59/194 (30%), Positives = 86/194 (44%), Gaps = 21/194 (10%)
Query: 69 QITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNVLCRCSDHC 128
Q FPGC C KT C C C D + CL A ++C V+ C
Sbjct: 555 QNRFPGCRC-KTQCNTKQCPCYLAVRECDPDLCLTC------GASEHWDCKVVS-----C 602
Query: 129 RNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKS 188
+N +Q+GL+ H + + GWG E + K F+ EY GE++ E RR + K
Sbjct: 603 KNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKY 662
Query: 189 DSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFA 248
S+++ + + VD T GN RF NHS PN V ++ ++ +FA
Sbjct: 663 MSSFLFNLNN--------DFVVDATRKGNKIRFANHSVNPNCYAKVVMVNG-DHRIGIFA 713
Query: 249 AKDIVPEEELSYDY 262
+ I EEL +DY
Sbjct: 714 KRAIQAGEELFFDY 727
>gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens]
Length = 707
Score = 75.1 bits (183), Expect = 2e-13
Identities = 41/104 (39%), Positives = 60/104 (57%), Gaps = 10/104 (9%)
Query: 87 CSCLRHGENYDDNSCLRD--IGSGGKYAE-------PVFECNVLCRCSDH-CRNRVVQKG 136
C+CL+ S L I +G KY ++EC++LC+C+ C+NRVVQ G
Sbjct: 293 CACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHG 352
Query: 137 LQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQR 180
Q QVFKT +KGWG+R L+ I +G FVC Y+G +L + ++
Sbjct: 353 PQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEK 396
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/88 (38%), Positives = 45/88 (51%), Gaps = 14/88 (15%)
Query: 210 VDPTYIGNIGRFLNHSCEPNLLMIPVRIDS---MVPKLALFAAKDIVPEEELSYDYSGRY 266
+D T GN+GRFLNHSC PNLL+ V +++ P +A F + + EL++DY Y
Sbjct: 626 LDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYG--Y 683
Query: 267 LNLTVSEDKERLDHGKLRKPCYCGAKSC 294
TV E KE C CG C
Sbjct: 684 EAGTVPE-KEIF--------CQCGVNKC 702
>gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens]
Length = 719
Score = 75.1 bits (183), Expect = 2e-13
Identities = 41/104 (39%), Positives = 60/104 (57%), Gaps = 10/104 (9%)
Query: 87 CSCLRHGENYDDNSCLRD--IGSGGKYAE-------PVFECNVLCRCSDH-CRNRVVQKG 136
C+CL+ S L I +G KY ++EC++LC+C+ C+NRVVQ G
Sbjct: 305 CACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHG 364
Query: 137 LQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQR 180
Q QVFKT +KGWG+R L+ I +G FVC Y+G +L + ++
Sbjct: 365 PQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEK 408
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/88 (38%), Positives = 45/88 (51%), Gaps = 14/88 (15%)
Query: 210 VDPTYIGNIGRFLNHSCEPNLLMIPVRIDS---MVPKLALFAAKDIVPEEELSYDYSGRY 266
+D T GN+GRFLNHSC PNLL+ V +++ P +A F + + EL++DY Y
Sbjct: 638 LDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYG--Y 695
Query: 267 LNLTVSEDKERLDHGKLRKPCYCGAKSC 294
TV E KE C CG C
Sbjct: 696 EAGTVPE-KEIF--------CQCGVNKC 714
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 73.2 bits (178), Expect = 8e-13
Identities = 54/201 (26%), Positives = 82/201 (40%), Gaps = 35/201 (17%)
Query: 69 QITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNVLCRCSDH- 127
Q FPGC C K C C C D + CL C +DH
Sbjct: 515 QNRFPGCRC-KAQCNTKQCPCYLAVRECDPDLCLT------------------CGAADHW 555
Query: 128 ------CRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRR 181
C+N +Q+G + H + + GWG+ + + K F+ EY GE++ E RR
Sbjct: 556 DSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRR 615
Query: 182 IHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMV 241
+ K +++ + + VD T GN RF NHS PN + ++
Sbjct: 616 GKVYDKYMCSFLFNLNN--------DFVVDATRKGNKIRFANHSVNPNCYAKVMMVNG-D 666
Query: 242 PKLALFAAKDIVPEEELSYDY 262
++ +FA + I EEL +DY
Sbjct: 667 HRIGIFAKRAIQTGEELFFDY 687
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 73.2 bits (178), Expect = 8e-13
Identities = 54/201 (26%), Positives = 82/201 (40%), Gaps = 35/201 (17%)
Query: 69 QITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNVLCRCSDH- 127
Q FPGC C K C C C D + CL C +DH
Sbjct: 559 QNRFPGCRC-KAQCNTKQCPCYLAVRECDPDLCLT------------------CGAADHW 599
Query: 128 ------CRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRR 181
C+N +Q+G + H + + GWG+ + + K F+ EY GE++ E RR
Sbjct: 600 DSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRR 659
Query: 182 IHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMV 241
+ K +++ + + VD T GN RF NHS PN + ++
Sbjct: 660 GKVYDKYMCSFLFNLNN--------DFVVDATRKGNKIRFANHSVNPNCYAKVMMVNG-D 710
Query: 242 PKLALFAAKDIVPEEELSYDY 262
++ +FA + I EEL +DY
Sbjct: 711 HRIGIFAKRAIQTGEELFFDY 731
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 72.8 bits (177), Expect = 1e-12
Identities = 52/156 (33%), Positives = 71/156 (45%), Gaps = 20/156 (12%)
Query: 143 VFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIREHVYN 202
V+++ G GL I G V EYAG V+ + +R + DS I + +
Sbjct: 3833 VYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKR---EKYYDSKGIGCYMFRIDD 3889
Query: 203 GQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDY 262
+V VD T GN RF+NHSCEPN + ID + +FA + I EEL+YDY
Sbjct: 3890 SEV----VDATMHGNAARFINHSCEPNCYSRVINIDGQ-KHIVIFAMRKIYRGEELTYDY 3944
Query: 263 SGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
K ++ + PC CGAK C FL
Sbjct: 3945 ------------KFPIEDASNKLPCNCGAKKCRKFL 3968
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 68.6 bits (166), Expect = 2e-11
Identities = 44/150 (29%), Positives = 75/150 (50%), Gaps = 25/150 (16%)
Query: 151 WGLRTLEFIPKGRFVCEYAGEVLG--FSEVQRRIHLQTKSDSNYIIAIREHVYNGQVMET 208
WGL +E I V EY G+ + ++++ + ++Q S+Y+ + +H +T
Sbjct: 1580 WGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRV-DH-------DT 1631
Query: 209 FVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDYSGRYLN 268
+D T GN+ RF+NH C PN + I+S K+ +++ + I +EE++YDY
Sbjct: 1632 IIDATKCGNLARFINHCCTPNCYAKVITIESQ-KKIVIYSKQPIGVDEEITYDY------ 1684
Query: 269 LTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
K L+ K+ PC CG +SC L
Sbjct: 1685 ------KFPLEDNKI--PCLCGTESCRGSL 1706
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 66.2 bits (160), Expect = 9e-11
Identities = 43/156 (27%), Positives = 76/156 (48%), Gaps = 25/156 (16%)
Query: 145 KTHKKGWGLRTLEFIPKGRFVCEYAGEVLG--FSEVQRRIHLQTKSDSNYIIAIREHVYN 202
K+H WGL +E I V EY G+ + ++++ + + S+Y+ + +H
Sbjct: 1790 KSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRV-DH--- 1845
Query: 203 GQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDY 262
+T +D T GN RF+NHSC PN + ++S K+ +++ + I EE++YDY
Sbjct: 1846 ----DTIIDATKCGNFARFINHSCNPNCYAKVITVESQ-KKIVIYSKQHINVNEEITYDY 1900
Query: 263 SGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
K ++ K+ PC CG+++C L
Sbjct: 1901 ------------KFPIEDVKI--PCLCGSENCRGTL 1922
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 65.1 bits (157), Expect = 2e-10
Identities = 51/165 (30%), Positives = 72/165 (43%), Gaps = 38/165 (23%)
Query: 143 VFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIREHVYN 202
V+++ G GL I G V EY+G V+ R L K RE Y+
Sbjct: 2579 VYRSAIHGRGLFCKRNIDAGEMVIEYSGIVI-------RSVLTDK---------REKFYD 2622
Query: 203 GQVMETF---------VDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIV 253
G+ + + VD T GN RF+NHSCEPN + ++ + +FA + I+
Sbjct: 2623 GKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQ-KHIVIFALRRIL 2681
Query: 254 PEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
EEL+YDY K ++ + PC CGAK C FL
Sbjct: 2682 RGEELTYDY------------KFPIEDASNKLPCNCGAKRCRRFL 2714
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 57.8 bits (138), Expect = 3e-08
Identities = 42/152 (27%), Positives = 69/152 (45%), Gaps = 24/152 (15%)
Query: 149 KGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSN-YIIAIR-EHVYNGQVM 206
+G GL + + K V EY G ++ RR + + + Y+ I EHV
Sbjct: 5407 QGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHV------ 5460
Query: 207 ETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDYSGRY 266
+D T G R++NHSC PN + V D K+ + +++ I EEL+YDY
Sbjct: 5461 ---IDATLTGGPARYINHSCAPNCVAEVVTFDK-EDKIIIISSRRIPKGEELTYDY---- 5512
Query: 267 LNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
+D+ ++ PC+CGA +C ++
Sbjct: 5513 -QFDFEDDQHKI-------PCHCGAWNCRKWM 5536
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 52.8 bits (125), Expect = 1e-06
Identities = 42/153 (27%), Positives = 68/153 (44%), Gaps = 26/153 (16%)
Query: 149 KGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIR---EHVYNGQV 205
+G GL I K V EY G ++ +EV R +S + + R +HV
Sbjct: 4781 QGLGLYAARDIEKHTMVIEYIGTIIR-NEVANRKEKLYESQNRGVYMFRMDNDHV----- 4834
Query: 206 METFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDYSGR 265
+D T G R++NHSC PN + V + K+ + +++ I EEL YDY
Sbjct: 4835 ----IDATLTGGPARYINHSCAPNCVAEVVTFE-RGHKIIISSSRRIQKGEELCYDY--- 4886
Query: 266 YLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
+D+ ++ PC+CGA +C ++
Sbjct: 4887 --KFDFEDDQHKI-------PCHCGAVNCRKWM 4910
>gi|45356743 SET domain-containing 8 [Homo sapiens]
Length = 352
Score = 50.1 bits (118), Expect = 7e-06
Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 11/140 (7%)
Query: 130 NRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRR--IHLQTK 187
+ +++ G + ++ KG G+ + +G FV EY G+++ ++ ++R ++ Q
Sbjct: 207 DELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDP 266
Query: 188 SDSNYIIAIREHVYNGQVMETF-VDPTYIGN-IGRFLNHSCEPNLLMIPVRIDSMVPKLA 245
S Y+ Y + +T+ VD T N +GR +NHS N ID VP L
Sbjct: 267 STGCYMY------YFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDG-VPHLI 319
Query: 246 LFAAKDIVPEEELSYDYSGR 265
L A++DI EEL YDY R
Sbjct: 320 LIASRDIAAGEELLYDYGDR 339
>gi|122937492 SET domain containing 5 [Homo sapiens]
Length = 1442
Score = 43.5 bits (101), Expect = 6e-04
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 7/148 (4%)
Query: 128 CRNRVVQKGLQFHF-QVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQT 186
C N V+ +Q +V + K LR + + EY G+V+ + + H
Sbjct: 260 CNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFK 319
Query: 187 KSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLAL 246
K Y + +NG +E VD GN RF+ SC PN + + D M+ L +
Sbjct: 320 KP---YPFVLFYSKFNG--VEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMI-HLCI 373
Query: 247 FAAKDIVPEEELSYDYSGRYLNLTVSED 274
+A I + E++ + Y N D
Sbjct: 374 YAVSAITKDAEVTIAFDYEYSNCNYKVD 401
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,121,838
Number of Sequences: 37866
Number of extensions: 1446524
Number of successful extensions: 3729
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 3609
Number of HSP's gapped (non-prelim): 86
length of query: 684
length of database: 18,247,518
effective HSP length: 109
effective length of query: 575
effective length of database: 14,120,124
effective search space: 8119071300
effective search space used: 8119071300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.