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Search of human proteins with 194306633
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo
sapiens]
(345 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 682 0.0
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 664 0.0
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 446 e-125
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 445 e-125
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 441 e-124
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 414 e-116
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 411 e-115
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 407 e-114
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 405 e-113
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 390 e-109
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 336 2e-92
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 336 2e-92
gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens] 251 9e-67
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 95 1e-19
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 94 2e-19
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 94 2e-19
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 94 2e-19
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 88 1e-17
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 86 4e-17
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 86 4e-17
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 83 3e-16
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 80 2e-15
gi|17402900 far upstream element-binding protein [Homo sapiens] 80 2e-15
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 79 6e-15
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 77 3e-14
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 76 5e-14
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 72 6e-13
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 58 1e-08
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 58 1e-08
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 58 1e-08
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 682 bits (1761), Expect = 0.0
Identities = 345/345 (100%), Positives = 345/345 (100%)
Query: 1 MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI 60
MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI
Sbjct: 1 MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI 60
Query: 61 IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS 120
IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS
Sbjct: 61 IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS 120
Query: 121 NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI
Sbjct: 121 NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
Query: 181 SGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPG 240
SGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPG
Sbjct: 181 SGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPG 240
Query: 241 EKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQ 300
EKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQ
Sbjct: 241 EKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQ 300
Query: 301 IKIANATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGTL 345
IKIANATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGTL
Sbjct: 301 IKIANATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGTL 345
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 664 bits (1713), Expect = 0.0
Identities = 345/371 (92%), Positives = 345/371 (92%), Gaps = 26/371 (7%)
Query: 1 MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI 60
MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI
Sbjct: 1 MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI 60
Query: 61 IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS 120
IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS
Sbjct: 61 IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS 120
Query: 121 NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI
Sbjct: 121 NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
Query: 181 SGTPDAIIQCVKQICVVMLE-------------------------AYTIQGQYAIPHPD- 214
SGTPDAIIQCVKQICVVMLE AYTIQGQYAIPHPD
Sbjct: 181 SGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQ 240
Query: 215 LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTI 274
LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTI
Sbjct: 241 LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTI 300
Query: 275 PNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINAR 334
PNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINAR
Sbjct: 301 PNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINAR 360
Query: 335 LTSEVTGMGTL 345
LTSEVTGMGTL
Sbjct: 361 LTSEVTGMGTL 371
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 446 bits (1148), Expect = e-125
Identities = 241/337 (71%), Positives = 269/337 (79%), Gaps = 32/337 (9%)
Query: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLE------------ 200
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 201 -------------AYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHS 247
AYTIQGQYAIP PDLTKLHQLAMQQ+ F P+ N F G + S
Sbjct: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHF-PMTHGNTGFSG----IES 235
Query: 248 SEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANAT 307
S + + G +GLDAS ++HELTIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN
Sbjct: 236 S--SPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPV 293
Query: 308 EGSSERQITITGTPANISLAQYLINARLTSEVTGMGT 344
EGS++RQ+TITG+ A+ISLAQYLIN RL+SE GMG+
Sbjct: 294 EGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 330
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 445 bits (1144), Expect = e-125
Identities = 242/341 (70%), Positives = 269/341 (78%), Gaps = 36/341 (10%)
Query: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLE------------ 200
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 201 -----------------AYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKL 243
AYTIQGQYAIP PDLTKLHQLAMQQ+ FP + N F G +
Sbjct: 181 PYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFP-MTHGNTGFSGIE- 238
Query: 244 PLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI 303
SS E + G +GLDAS ++HELTIPNDLIGCIIGRQG KINEIRQMSGAQIKI
Sbjct: 239 --SSSPEVK---GYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKI 293
Query: 304 ANATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGT 344
AN EGS++RQ+TITG+ A+ISLAQYLIN RL+SE GMG+
Sbjct: 294 ANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 334
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 441 bits (1133), Expect = e-124
Identities = 239/338 (70%), Positives = 263/338 (77%), Gaps = 47/338 (13%)
Query: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLE------------ 200
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 201 -------------AYTIQGQYAIPHPDLTKLHQLAMQQTPFPPL-GQTNPAFPGEKLPLH 246
AYTIQGQYAIP PDLTKLHQLAMQQ+ FP G T
Sbjct: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNT------------ 228
Query: 247 SSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANA 306
G S+GLDAS ++HELTIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN
Sbjct: 229 ---------GFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP 279
Query: 307 TEGSSERQITITGTPANISLAQYLINARLTSEVTGMGT 344
EGS++RQ+TITG+ A+ISLAQYLIN RL+SE GMG+
Sbjct: 280 VEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 317
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 414 bits (1063), Expect = e-116
Identities = 236/368 (64%), Positives = 267/368 (72%), Gaps = 63/368 (17%)
Query: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEA----YTI---- 204
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE+ TI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 205 ------------QGQY-------AIPH-----------------------------PDLT 216
Q +Y + PH PDLT
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
Query: 217 KLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPN 276
KLHQLAMQQ+ F P+ N F G + SS + + G +GLDAS ++HELTIPN
Sbjct: 241 KLHQLAMQQSHF-PMTHGNTGFSG----IESS--SPEVKGYWAGLDASAQTTSHELTIPN 293
Query: 277 DLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLT 336
DLIGCIIGRQG KINEIRQMSGAQIKIAN EGS++RQ+TITG+ A+ISLAQYLIN RL+
Sbjct: 294 DLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLS 353
Query: 337 SEVTGMGT 344
SE GMG+
Sbjct: 354 SETGGMGS 361
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 411 bits (1057), Expect = e-115
Identities = 236/368 (64%), Positives = 265/368 (72%), Gaps = 64/368 (17%)
Query: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEA----YTI---- 204
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE+ TI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 205 ------------QGQY-------AIPH-----------------------------PDLT 216
Q +Y + PH PDLT
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
Query: 217 KLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPN 276
KLHQLAMQQ+ F P+ N F G + SS E + GLDAS ++HELTIPN
Sbjct: 241 KLHQLAMQQSHF-PMTHGNTGFSGIE---SSSPEVKGYW----GLDASAQTTSHELTIPN 292
Query: 277 DLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLT 336
DLIGCIIGRQG KINEIRQMSGAQIKIAN EGS++RQ+TITG+ A+ISLAQYLIN RL+
Sbjct: 293 DLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLS 352
Query: 337 SEVTGMGT 344
SE GMG+
Sbjct: 353 SETGGMGS 360
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 407 bits (1047), Expect = e-114
Identities = 234/372 (62%), Positives = 265/372 (71%), Gaps = 67/372 (18%)
Query: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTI-------- 204
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE +
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 205 ----------------QGQY-------AIPH--------PDL------------------ 215
Q +Y + PH PDL
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 216 ---TKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHEL 272
TKLHQLAMQQ+ F P+ N F G + SS + + G +GLDAS ++HEL
Sbjct: 241 PDLTKLHQLAMQQSHF-PMTHGNTGFSG----IESS--SPEVKGYWAGLDASAQTTSHEL 293
Query: 273 TIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 332
TIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN EGS++RQ+TITG+ A+ISLAQYLIN
Sbjct: 294 TIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLIN 353
Query: 333 ARLTSEVTGMGT 344
RL+SE GMG+
Sbjct: 354 VRLSSETGGMGS 365
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 405 bits (1041), Expect = e-113
Identities = 234/372 (62%), Positives = 263/372 (70%), Gaps = 68/372 (18%)
Query: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTI-------- 204
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE +
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 205 ----------------QGQY-------AIPH--------PDL------------------ 215
Q +Y + PH PDL
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 216 ---TKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHEL 272
TKLHQLAMQQ+ F P+ N F G + SS E + GLDAS ++HEL
Sbjct: 241 PDLTKLHQLAMQQSHF-PMTHGNTGFSGIE---SSSPEVKGYW----GLDASAQTTSHEL 292
Query: 273 TIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 332
TIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN EGS++RQ+TITG+ A+ISLAQYLIN
Sbjct: 293 TIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLIN 352
Query: 333 ARLTSEVTGMGT 344
RL+SE GMG+
Sbjct: 353 VRLSSETGGMGS 364
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 390 bits (1002), Expect = e-109
Identities = 222/363 (61%), Positives = 256/363 (70%), Gaps = 61/363 (16%)
Query: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
M++ V+E GLNVTLTIRLLMHGKEVGSIIGKKGE+VK++REESGARINISEGNCPERI+T
Sbjct: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60
Query: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
+TGPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPA+QCGSLIGKGG KI
Sbjct: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120
Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLE------------ 200
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P ++ +CVKQIC+VMLE
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180
Query: 201 ----------------------------------------AYTIQGQYAIPHPDLTKLHQ 220
AY+IQGQ+ I DL KL+Q
Sbjct: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ 240
Query: 221 LAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIG 280
+A QQ+ F + F G + + G + LDAS +THELTIPN+LIG
Sbjct: 241 VARQQSHFAMM-HGGTGFAG------IDSSSPEVKGYWASLDAS-TQTTHELTIPNNLIG 292
Query: 281 CIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLTSEVT 340
CIIGRQG INEIRQMSGAQIKIAN EGSS RQ+TITG+ A+ISLAQYLINARL+SE
Sbjct: 293 CIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE-K 351
Query: 341 GMG 343
GMG
Sbjct: 352 GMG 354
Score = 37.7 bits (86), Expect = 0.015
Identities = 25/67 (37%), Positives = 38/67 (56%), Gaps = 4/67 (5%)
Query: 279 IGCIIGRQGTKINEIRQMSGAQIKIANATEGS-SERQITITGTPANISLAQYLINARLTS 337
+G IIG++G + IR+ SGA+I N +EG+ ER IT+TG I A +I +L
Sbjct: 25 VGSIIGKKGESVKRIREESGARI---NISEGNCPERIITLTGPTNAIFKAFAMIIDKLEE 81
Query: 338 EVTGMGT 344
++ T
Sbjct: 82 DINSSMT 88
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 336 bits (862), Expect = 2e-92
Identities = 185/310 (59%), Positives = 223/310 (71%), Gaps = 5/310 (1%)
Query: 39 EGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTD 98
E L++TLT+R+LMHGKEVGSIIGKKGETVK++RE+S ARI ISEG+CPERI TITG T
Sbjct: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
Query: 99 AIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRES 158
A+F A +MIA+K +ED+ + +N S+PPVTLRLV+PASQCGSLIGK G+KIKEIRE+
Sbjct: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
Query: 159 TGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKL 218
TGAQVQVAGD+LPNSTERAVT+SG PDAII CV+QIC V+LE+ +G HP L+
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILES-PPKGATIPYHPSLSLG 189
Query: 219 HQLAMQQTPFPPLGQTNPAFPGEKLPLHS-SEEAQNLMGQS--SGLDASPPASTHELTIP 275
L F GQ P E L S A S GLD S+ E +P
Sbjct: 190 TVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVP 249
Query: 276 NDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARL 335
NDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ ER +TITG+P +I+LAQYLI A L
Sbjct: 250 NDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACL 309
Query: 336 -TSEVTGMGT 344
T++ T GT
Sbjct: 310 ETAKSTSGGT 319
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 336 bits (862), Expect = 2e-92
Identities = 185/310 (59%), Positives = 223/310 (71%), Gaps = 5/310 (1%)
Query: 39 EGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTD 98
E L++TLT+R+LMHGKEVGSIIGKKGETVK++RE+S ARI ISEG+CPERI TITG T
Sbjct: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
Query: 99 AIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRES 158
A+F A +MIA+K +ED+ + +N S+PPVTLRLV+PASQCGSLIGK G+KIKEIRE+
Sbjct: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
Query: 159 TGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKL 218
TGAQVQVAGD+LPNSTERAVT+SG PDAII CV+QIC V+LE+ +G HP L+
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILES-PPKGATIPYHPSLSLG 189
Query: 219 HQLAMQQTPFPPLGQTNPAFPGEKLPLHS-SEEAQNLMGQS--SGLDASPPASTHELTIP 275
L F GQ P E L S A S GLD S+ E +P
Sbjct: 190 TVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVP 249
Query: 276 NDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARL 335
NDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ ER +TITG+P +I+LAQYLI A L
Sbjct: 250 NDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACL 309
Query: 336 -TSEVTGMGT 344
T++ T GT
Sbjct: 310 ETAKSTSGGT 319
>gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]
Length = 424
Score = 251 bits (640), Expect = 9e-67
Identities = 156/330 (47%), Positives = 190/330 (57%), Gaps = 60/330 (18%)
Query: 74 ESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLR 133
+S ARI ISEG+CPERI TITG T A+F A +MIA+K +ED+ + +N S+PPVTLR
Sbjct: 12 QSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLR 71
Query: 134 LVVPASQCGSLIGKGGSKIK---EIR---------------------------------- 156
LV+PASQCGSLIGK G+KIK E+R
Sbjct: 72 LVIPASQCGSLIGKAGTKIKEIREVRGEIYHPQGIRGKGAVVRGVLGLWRPPHLESSEPG 131
Query: 157 ------------------ESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVM 198
++TGAQVQVAGD+LPNSTERAVT+SG PDAII CV+QIC V+
Sbjct: 132 QPFSGLWEQPEVAPVLCLQTTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVI 191
Query: 199 LEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHS-SEEAQNLMGQ 257
LE+ +G HP L+ L F GQ P E L S A
Sbjct: 192 LESPP-KGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATP 250
Query: 258 S--SGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 315
S GLD S+ E +PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ ER +
Sbjct: 251 SVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHV 310
Query: 316 TITGTPANISLAQYLINARL-TSEVTGMGT 344
TITG+P +I+LAQYLI A L T++ T GT
Sbjct: 311 TITGSPVSIALAQYLITACLETAKSTSGGT 340
Score = 45.4 bits (106), Expect = 7e-05
Identities = 41/135 (30%), Positives = 59/135 (43%), Gaps = 10/135 (7%)
Query: 135 VVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQI 194
+VP G +IG+ GSKI EIR+ +GA +++ G+ + ER VTI+G+P +I I
Sbjct: 268 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQAEGAGERHVTITGSPVSIALAQYLI 326
Query: 195 CVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNL 254
+ A + G P A PF P P P L + N
Sbjct: 327 TACLETAKSTSGGTPSSAP--------ADLPAPFSPPLTALPTAPPGLLGTPYAISLSNF 378
Query: 255 MG-QSSGLDASPPAS 268
+G + A PPAS
Sbjct: 379 IGLKPMPFLALPPAS 393
Score = 37.4 bits (85), Expect = 0.020
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 11/97 (11%)
Query: 57 VGSIIGKKGETVKKMREESGARINI---SEGNCPERIVTITGPTDAIFKAFAMIAYKFEE 113
+G +IG++G + ++R+ SGA I I +EG ER VTITG +I A +I E
Sbjct: 274 IGCVIGRQGSKISEIRQMSGAHIKIGNQAEG-AGERHVTITGSPVSIALAQYLITACLET 332
Query: 114 DIINS-------MSNSPATSKPPVTLRLVVPASQCGS 143
S ++ PA PP+T P G+
Sbjct: 333 AKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGT 369
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 94.7 bits (234), Expect = 1e-19
Identities = 98/355 (27%), Positives = 161/355 (45%), Gaps = 35/355 (9%)
Query: 11 SVLPHSTLSTLSHHPQPQFGRRM--ESKVSEGGLN----VTLTIRLLMHGKEVGSIIGKK 64
S +P +S+ S + Q G E + GG + + +R+L+ + VG+IIGK+
Sbjct: 153 SYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKE 212
Query: 65 GETVKKMREESGARINI---SEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSN 121
G T+K + +++ +R++I E+ VTI + +A MI +I+ ++
Sbjct: 213 GLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL-----EIMQKEAD 267
Query: 122 SPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVT 179
++ + L+++ G LIGK G +K+I TG ++ ++ D+ + ER +T
Sbjct: 268 ETKLAEE-IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
Query: 180 ISGTPDAIIQCVKQICVVMLEAY------TIQGQYAIPHPDLTKLH----QLAMQQTPFP 229
+ GT +A +I + EA+ Q IP +L+ L L++ P
Sbjct: 327 VKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAG 386
Query: 230 PLGQTNPAFPGEKLPLHS----SEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGR 285
P G PA P HS S + G + P L IP +G IIG+
Sbjct: 387 PRGAP-PAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGK 445
Query: 286 QGTKINEIRQMSGAQIKIANATEGS--SERQITITGTPANISLAQYLINARLTSE 338
+G I ++ + +GA IKIA A EG SER + ITG P AQ I +L E
Sbjct: 446 KGAHIKQLARFAGASIKIAPA-EGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
Score = 76.3 bits (186), Expect = 4e-14
Identities = 49/134 (36%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPTDAIFKAF 104
+ L + + VG+IIGKKG +K++ +GA I I+ P ER+V ITGP +A FKA
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
I K +E+ + N K +R VP+S G +IGKGG + E++ T A+V
Sbjct: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
Query: 165 VAGDMLPNSTERAV 178
V D P+ E +
Sbjct: 545 VPRDQTPDENEEVI 558
Score = 28.5 bits (62), Expect = 9.2
Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 29 FGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP- 87
FG+ E V L + + G +IGK G+TV +++ + A + + P
Sbjct: 493 FGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 552
Query: 88 ---ERIVTITG 95
E IV I G
Sbjct: 553 ENEEVIVRIIG 563
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 93.6 bits (231), Expect = 2e-19
Identities = 52/174 (29%), Positives = 95/174 (54%), Gaps = 22/174 (12%)
Query: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMI 107
+R+L+ K G++IGK G+ +K +R + A +++ + + PERI++I+ + I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 108 AYKFEEDIINSMSNSPATSKPPVT--------------------LRLVVPASQCGSLIGK 147
EE + + + ATS+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGL--QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 148 GGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEA 201
G+KIKE+RE+T +++ + P+ST+R V I G PD +++C+K I ++ E+
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISES 216
Score = 70.9 bits (172), Expect = 2e-12
Identities = 39/76 (51%), Positives = 47/76 (61%)
Query: 256 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 315
G+ S D P T ++TIP DL G IIG+ G +I +IR SGA IKI EGS +R I
Sbjct: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRII 435
Query: 316 TITGTPANISLAQYLI 331
TITGT I AQYL+
Sbjct: 436 TITGTQDQIQNAQYLL 451
Score = 54.7 bits (130), Expect = 1e-07
Identities = 25/60 (41%), Positives = 40/60 (66%), Gaps = 1/60 (1%)
Query: 128 PPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAI 187
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R +TI+GT D I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
Score = 49.7 bits (117), Expect = 4e-06
Identities = 54/198 (27%), Positives = 82/198 (41%), Gaps = 41/198 (20%)
Query: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
V LR+++ + G++IGKGG IK +R A V V P ER ++IS + I +
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHS-S 248
+K+I T++ +P P T +LPL S +
Sbjct: 100 ILKKIIP------TLEEGLQLPSPTAT------------------------SQLPLESDA 129
Query: 249 EEAQNLMG-QSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI-ANA 306
E N + S D L I L G IIG +G KI E+R+ + IK+
Sbjct: 130 VECLNYQHYKGSDFDCE-----LRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
Query: 307 TEGSSERQITITGTPANI 324
S++R + I G P +
Sbjct: 185 CPHSTDRVVLIGGKPDRV 202
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/48 (52%), Positives = 31/48 (64%), Gaps = 2/48 (4%)
Query: 58 GSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKA 103
GSIIGK G+ +K++R ESGA I I E +RI+TITG D I A
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
Score = 43.1 bits (100), Expect = 4e-04
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 41 GLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPT 97
G + +RLL+H G IIG KG +K++RE + I + + CP +R+V I G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 98 DAIFKAFAMI 107
D + + +I
Sbjct: 200 DRVVECIKII 209
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 93.6 bits (231), Expect = 2e-19
Identities = 52/174 (29%), Positives = 95/174 (54%), Gaps = 22/174 (12%)
Query: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMI 107
+R+L+ K G++IGK G+ +K +R + A +++ + + PERI++I+ + I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 108 AYKFEEDIINSMSNSPATSKPPVT--------------------LRLVVPASQCGSLIGK 147
EE + + + ATS+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGL--QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 148 GGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEA 201
G+KIKE+RE+T +++ + P+ST+R V I G PD +++C+K I ++ E+
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISES 216
Score = 70.9 bits (172), Expect = 2e-12
Identities = 39/76 (51%), Positives = 47/76 (61%)
Query: 256 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 315
G+ S D P T ++TIP DL G IIG+ G +I +IR SGA IKI EGS +R I
Sbjct: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRII 435
Query: 316 TITGTPANISLAQYLI 331
TITGT I AQYL+
Sbjct: 436 TITGTQDQIQNAQYLL 451
Score = 54.7 bits (130), Expect = 1e-07
Identities = 25/60 (41%), Positives = 40/60 (66%), Gaps = 1/60 (1%)
Query: 128 PPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAI 187
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R +TI+GT D I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
Score = 49.7 bits (117), Expect = 4e-06
Identities = 54/198 (27%), Positives = 82/198 (41%), Gaps = 41/198 (20%)
Query: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
V LR+++ + G++IGKGG IK +R A V V P ER ++IS + I +
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHS-S 248
+K+I T++ +P P T +LPL S +
Sbjct: 100 ILKKIIP------TLEEGLQLPSPTAT------------------------SQLPLESDA 129
Query: 249 EEAQNLMG-QSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI-ANA 306
E N + S D L I L G IIG +G KI E+R+ + IK+
Sbjct: 130 VECLNYQHYKGSDFDCE-----LRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
Query: 307 TEGSSERQITITGTPANI 324
S++R + I G P +
Sbjct: 185 CPHSTDRVVLIGGKPDRV 202
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/48 (52%), Positives = 31/48 (64%), Gaps = 2/48 (4%)
Query: 58 GSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKA 103
GSIIGK G+ +K++R ESGA I I E +RI+TITG D I A
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
Score = 43.1 bits (100), Expect = 4e-04
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 41 GLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPT 97
G + +RLL+H G IIG KG +K++RE + I + + CP +R+V I G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 98 DAIFKAFAMI 107
D + + +I
Sbjct: 200 DRVVECIKII 209
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 93.6 bits (231), Expect = 2e-19
Identities = 52/174 (29%), Positives = 95/174 (54%), Gaps = 22/174 (12%)
Query: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMI 107
+R+L+ K G++IGK G+ +K +R + A +++ + + PERI++I+ + I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 108 AYKFEEDIINSMSNSPATSKPPVT--------------------LRLVVPASQCGSLIGK 147
EE + + + ATS+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGL--QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 148 GGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEA 201
G+KIKE+RE+T +++ + P+ST+R V I G PD +++C+K I ++ E+
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISES 216
Score = 70.9 bits (172), Expect = 2e-12
Identities = 39/76 (51%), Positives = 47/76 (61%)
Query: 256 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 315
G+ S D P T ++TIP DL G IIG+ G +I +IR SGA IKI EGS +R I
Sbjct: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRII 435
Query: 316 TITGTPANISLAQYLI 331
TITGT I AQYL+
Sbjct: 436 TITGTQDQIQNAQYLL 451
Score = 54.7 bits (130), Expect = 1e-07
Identities = 25/60 (41%), Positives = 40/60 (66%), Gaps = 1/60 (1%)
Query: 128 PPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAI 187
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R +TI+GT D I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
Score = 49.7 bits (117), Expect = 4e-06
Identities = 54/198 (27%), Positives = 82/198 (41%), Gaps = 41/198 (20%)
Query: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
V LR+++ + G++IGKGG IK +R A V V P ER ++IS + I +
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHS-S 248
+K+I T++ +P P T +LPL S +
Sbjct: 100 ILKKIIP------TLEEGLQLPSPTAT------------------------SQLPLESDA 129
Query: 249 EEAQNLMG-QSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI-ANA 306
E N + S D L I L G IIG +G KI E+R+ + IK+
Sbjct: 130 VECLNYQHYKGSDFDCE-----LRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
Query: 307 TEGSSERQITITGTPANI 324
S++R + I G P +
Sbjct: 185 CPHSTDRVVLIGGKPDRV 202
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/48 (52%), Positives = 31/48 (64%), Gaps = 2/48 (4%)
Query: 58 GSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKA 103
GSIIGK G+ +K++R ESGA I I E +RI+TITG D I A
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
Score = 43.1 bits (100), Expect = 4e-04
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 41 GLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPT 97
G + +RLL+H G IIG KG +K++RE + I + + CP +R+V I G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 98 DAIFKAFAMI 107
D + + +I
Sbjct: 200 DRVVECIKII 209
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 88.2 bits (217), Expect = 1e-17
Identities = 89/341 (26%), Positives = 153/341 (44%), Gaps = 50/341 (14%)
Query: 11 SVLPHSTLSTLSHHPQPQFGRRM--ESKVSEGGLN----VTLTIRLLMHGKEVGSIIGKK 64
S +P +S+ S + Q G E + GG + + +R+L+ + VG+IIGK+
Sbjct: 153 SYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKE 212
Query: 65 GETVKKMREESGARINI---SEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSN 121
G T+K + +++ +R++I E+ VTI + +A MI +I+ ++
Sbjct: 213 GLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL-----EIMQKEAD 267
Query: 122 SPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVT 179
++ + L+++ G LIGK G +K+I TG ++ ++ D+ + ER +T
Sbjct: 268 ETKLAE-EIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
Query: 180 ISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFP 239
+ GT +A +I + EA+ D+ ++ + + P Q P
Sbjct: 327 VKGTVEACASAEIEIMKKLREAF---------ENDMLAVNTHSGYFSSLYPHHQFGP--- 374
Query: 240 GEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGA 299
P H S Q ++ L IP +G IIG++G I ++ + +GA
Sbjct: 375 ---FPHHHSYPEQEIV---------------NLFIPTQAVGAIIGKKGAHIKQLARFAGA 416
Query: 300 QIKIANATEGS--SERQITITGTPANISLAQYLINARLTSE 338
IKIA A EG SER + ITG P AQ I +L E
Sbjct: 417 SIKIAPA-EGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 456
Score = 76.3 bits (186), Expect = 4e-14
Identities = 49/134 (36%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPTDAIFKAF 104
+ L + + VG+IIGKKG +K++ +GA I I+ P ER+V ITGP +A FKA
Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
I K +E+ + N K +R VP+S G +IGKGG + E++ T A+V
Sbjct: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
Query: 165 VAGDMLPNSTERAV 178
V D P+ E +
Sbjct: 502 VPRDQTPDENEEVI 515
Score = 75.1 bits (183), Expect = 9e-14
Identities = 69/295 (23%), Positives = 119/295 (40%), Gaps = 82/295 (27%)
Query: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNC-----P 87
M+ + E L + +++L H VG +IGK+G +KK+ E+G +I IS P
Sbjct: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
Query: 88 ERIVTITGPTDAIFKAFAMIAYK----FEEDI--INSMSNSPATSKP------------- 128
ER +T+ G +A A I K FE D+ +N+ S ++ P
Sbjct: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSY 381
Query: 129 --PVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDA 186
+ L +P G++IGK G+ IK++ GA +++A P+ +ER V I+G P+A
Sbjct: 382 PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
Query: 187 IIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLH 246
Q Q F L + N P E++ L
Sbjct: 442 ---------------------------------QFKAQGRIFGKLKEENFFNPKEEVKLE 468
Query: 247 SSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 301
+ + +P+ G +IG+ G +NE++ ++ A++
Sbjct: 469 A-----------------------HIRVPSSTAGRVIGKGGKTVNELQNLTSAEV 500
Score = 28.5 bits (62), Expect = 9.2
Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 29 FGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP- 87
FG+ E V L + + G +IGK G+TV +++ + A + + P
Sbjct: 450 FGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 509
Query: 88 ---ERIVTITG 95
E IV I G
Sbjct: 510 ENEEVIVRIIG 520
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 86.3 bits (212), Expect = 4e-17
Identities = 86/328 (26%), Positives = 140/328 (42%), Gaps = 43/328 (13%)
Query: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103
+++++ G IIGK G TVK + E+SGA + +S+ N ER+VT++G + KA
Sbjct: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
Query: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVP-ASQCGSLIGKGG 149
+I K +ED + ++NS T P V+P A+ L+G
Sbjct: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
Query: 150 SKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYT---IQG 206
A V N + T + + + + + +A +
Sbjct: 294 LA------GVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAA 347
Query: 207 QYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKL--PLHSSEEAQN-LMGQSSGLDA 263
A +P + LA + G T G L ++ A N G +S L A
Sbjct: 348 AAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAA 407
Query: 264 SPPASTH----------ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATE---GS 310
S T E+ +P +L+G I+G+ G + E ++++GA+I+I+ E G+
Sbjct: 408 SAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT 467
Query: 311 SERQITITGTPANISLAQYLINARLTSE 338
R++TITGTPA AQYLI R+T E
Sbjct: 468 RNRKVTITGTPAATQAAQYLITQRITYE 495
Score = 73.6 bits (179), Expect = 2e-13
Identities = 60/208 (28%), Positives = 99/208 (47%), Gaps = 44/208 (21%)
Query: 27 PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85
P+ G + E G +++L+ GSIIGK G+T+ ++++E+GA I +S+
Sbjct: 34 PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
Query: 86 ----CPERIVTITGPTDAIFKAFAMIAYKFEE-----------------------DIINS 118
ER+ I G +A+ IA K E I +
Sbjct: 91 FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQT 150
Query: 119 MSNSPATSKP----PVT------LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVA-- 166
+ +SP T+K P+T ++++VP S G +IGKGG+ +K + E +GA VQ++
Sbjct: 151 LPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK 210
Query: 167 GDMLPNSTERAVTISGTPDAIIQCVKQI 194
D + N ER VT+SG P+ + V+ I
Sbjct: 211 PDGI-NLQERVVTVSGEPEQNRKAVELI 237
Score = 67.8 bits (164), Expect = 1e-11
Identities = 53/211 (25%), Positives = 101/211 (47%), Gaps = 22/211 (10%)
Query: 132 LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQ 189
L++++P+ GS+IGKGG I ++++ TGA ++++ D P +TER I GT +A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSE 249
+ + + +P ++ K +++ Q P NP + LP S
Sbjct: 112 ---------VHGFIAEKIREMPQ-NVAKTEPVSILQ----PQTTVNPDRIKQTLP---SS 154
Query: 250 EAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEG 309
S + S A+ ++ +PN G IIG+ G + + + SGA ++++ +G
Sbjct: 155 PTTTKSSPSDPMTTSR-ANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDG 213
Query: 310 SS--ERQITITGTPANISLAQYLINARLTSE 338
+ ER +T++G P A LI ++ +
Sbjct: 214 INLQERVVTVSGEPEQNRKAVELIIQKIQED 244
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 86.3 bits (212), Expect = 4e-17
Identities = 86/328 (26%), Positives = 140/328 (42%), Gaps = 43/328 (13%)
Query: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103
+++++ G IIGK G TVK + E+SGA + +S+ N ER+VT++G + KA
Sbjct: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
Query: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVP-ASQCGSLIGKGG 149
+I K +ED + ++NS T P V+P A+ L+G
Sbjct: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
Query: 150 SKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYT---IQG 206
A V N + T + + + + + +A +
Sbjct: 270 LA------GVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAA 323
Query: 207 QYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKL--PLHSSEEAQN-LMGQSSGLDA 263
A +P + LA + G T G L ++ A N G +S L A
Sbjct: 324 AAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAA 383
Query: 264 SPPASTH----------ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATE---GS 310
S T E+ +P +L+G I+G+ G + E ++++GA+I+I+ E G+
Sbjct: 384 SAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT 443
Query: 311 SERQITITGTPANISLAQYLINARLTSE 338
R++TITGTPA AQYLI R+T E
Sbjct: 444 RNRKVTITGTPAATQAAQYLITQRITYE 471
Score = 80.1 bits (196), Expect = 3e-15
Identities = 57/184 (30%), Positives = 92/184 (50%), Gaps = 20/184 (10%)
Query: 27 PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85
P+ G + E G +++L+ GSIIGK G+T+ ++++E+GA I +S+
Sbjct: 34 PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
Query: 86 ----CPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------L 132
ER+ I G +A+ IA K E N P + P T +
Sbjct: 91 FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQV 150
Query: 133 RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVA--GDMLPNSTERAVTISGTPDAIIQC 190
+++VP S G +IGKGG+ +K + E +GA VQ++ D + N ER VT+SG P+ +
Sbjct: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQNRKA 209
Query: 191 VKQI 194
V+ I
Sbjct: 210 VELI 213
Score = 35.4 bits (80), Expect = 0.075
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 6/82 (7%)
Query: 242 KLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 301
K PL + EA + ++G D ++ IP+ G IIG+ G I ++++ +GA I
Sbjct: 27 KRPLEAPPEAGSTKRTNTGEDGQ---YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATI 83
Query: 302 KIANATE---GSSERQITITGT 320
K++ + + G++ER I GT
Sbjct: 84 KLSKSKDFYPGTTERVCLIQGT 105
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 83.2 bits (204), Expect = 3e-16
Identities = 73/320 (22%), Positives = 141/320 (44%), Gaps = 25/320 (7%)
Query: 26 QPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---S 82
QP+ G + + V + +RLL+ + VG+IIGK+G T++ + +++ ++I++
Sbjct: 176 QPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKE 235
Query: 83 EGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCG 142
E+ +++ + A MI +I++ + T+ V L+++ + G
Sbjct: 236 NAGAAEKAISVHSTPEGCSSACKMIL-----EIMHKEAKDTKTA-DEVPLKILAHNNFVG 289
Query: 143 SLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQCVKQICVVMLE 200
LIGK G +K++ + T ++ ++ D+ + ER +T+ G + + ++I + E
Sbjct: 290 RLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVRE 349
Query: 201 AYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPA-FPGEKLPLHSSEEAQNLMGQSS 259
AY + +++Q P L FP + + S
Sbjct: 350 AYE------------NDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYS 397
Query: 260 GLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA-NATEGSSERQITIT 318
+P ++ IP +G IIG++G I ++ + + A IKIA T S R + IT
Sbjct: 398 SFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIIT 457
Query: 319 GTPANISLAQYLINARLTSE 338
G P AQ I +L E
Sbjct: 458 GPPEAQFKAQGRIYGKLKEE 477
Score = 72.4 bits (176), Expect = 6e-13
Identities = 43/134 (32%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIFKAF 104
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R+V ITGP +A FKA
Sbjct: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
I K +E+ + + + VPAS G +IGKGG + E++ T A+V
Sbjct: 468 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
Query: 165 VAGDMLPNSTERAV 178
V D P+ ++ +
Sbjct: 523 VPRDQTPDENDQVI 536
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 80.5 bits (197), Expect = 2e-15
Identities = 75/302 (24%), Positives = 139/302 (46%), Gaps = 29/302 (9%)
Query: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI----SEGNCPERIVTITGP--TDA 99
L +RLL+ + VG+IIGK+G T++ + +++ ++I++ + G + I ++ P T A
Sbjct: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
Query: 100 IFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIREST 159
K+ I +K +DI + L+++ + G LIGK G +K+I + T
Sbjct: 256 ACKSILEIMHKEAQDI---------KFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
Query: 160 GAQVQVAG--DMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTK 217
++ ++ ++ + ER +T+ G + + ++I + E+Y D+
Sbjct: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESY---------ENDIAS 357
Query: 218 LHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPND 277
++ L P L P +P +S + + S + H L IP
Sbjct: 358 MN-LQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVH-LFIPAL 415
Query: 278 LIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSE-RQITITGTPANISLAQYLINARLT 336
+G IIG+QG I ++ + +GA IKIA A ++ R + ITG P AQ I ++
Sbjct: 416 SVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIK 475
Query: 337 SE 338
E
Sbjct: 476 EE 477
Score = 73.9 bits (180), Expect = 2e-13
Identities = 45/137 (32%), Positives = 73/137 (53%), Gaps = 8/137 (5%)
Query: 45 TLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIF 101
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R+V ITGP +A F
Sbjct: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
Query: 102 KAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGA 161
KA I K +E+ S + + + VP+ G +IGKGG + E++ + A
Sbjct: 465 KAQGRIYGKIKEENFVS-----PKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
Query: 162 QVQVAGDMLPNSTERAV 178
+V V D P+ ++ V
Sbjct: 520 EVVVPRDQTPDENDQVV 536
Score = 72.8 bits (177), Expect = 4e-13
Identities = 74/338 (21%), Positives = 125/338 (36%), Gaps = 103/338 (30%)
Query: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN-----CPERIVTITGPTDAI 100
+ +++L H VG +IGK+G +KK+ +++ +I IS PER +T+ G +
Sbjct: 277 IPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETC 336
Query: 101 FKAFAMIAYKFEEDIINSMSNS-------------------------PATSKPPV----- 130
KA I K E N +++ P TS PP
Sbjct: 337 AKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPP 396
Query: 131 ----------TLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
T+ L +PA G++IGK G IK++ GA +++A P++ R V I
Sbjct: 397 YPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVII 456
Query: 181 SGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPG 240
+G P+A Q Q + + + N P
Sbjct: 457 TGPPEA---------------------------------QFKAQGRIYGKIKEENFVSPK 483
Query: 241 EKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQ 300
E++ L + + +P+ G +IG+ G +NE++ +S A+
Sbjct: 484 EEVKLEA-----------------------HIRVPSFAAGRVIGKGGKTVNELQNLSSAE 520
Query: 301 IKIANATEGSSERQIT--ITGTPANISLAQYLINARLT 336
+ + Q+ ITG +AQ I LT
Sbjct: 521 VVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEILT 558
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 122 SPATSKP-PVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
S + KP + LRL+VP G++IGK G+ I+ I + T +++ V + E+++TI
Sbjct: 187 SVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITI 246
Query: 181 SGTPDAIIQCVKQICVVM-LEAYTIQGQYAIP 211
TP+ K I +M EA I+ IP
Sbjct: 247 LSTPEGTSAACKSILEIMHKEAQDIKFTEEIP 278
Score = 28.9 bits (63), Expect = 7.0
Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 4/71 (5%)
Query: 29 FGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE 88
+G+ E V L + + G +IGK G+TV +++ S A + + P+
Sbjct: 471 YGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPD 530
Query: 89 R----IVTITG 95
+V ITG
Sbjct: 531 ENDQVVVKITG 541
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 80.5 bits (197), Expect = 2e-15
Identities = 82/350 (23%), Positives = 149/350 (42%), Gaps = 69/350 (19%)
Query: 57 VGSIIGKKGETVKKMREESGARINIS--EGNCPERIVTITGPTDAIFKAFAMIAYKFEED 114
VG IIG+ GE + ++++ESG +I I+ G PER +TG +++ A ++ +
Sbjct: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLL-----DQ 166
Query: 115 IINSMSNSPA----TSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDML 170
I+ +P +++PAS+ G +IGKGG IK+++E G ++ + D
Sbjct: 167 IVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGP 226
Query: 171 PNS-TERAVTISGTPDAIIQCVKQICVVMLEA---YTIQGQYA----------IPHPD-- 214
N+ ++ + I+G P + Q + + ++ + ++ +Y +P P
Sbjct: 227 QNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFA 286
Query: 215 -----------LTKLHQLAMQQTPFPPLGQTNP------AFPGEKLPLHSSEEAQNLM-- 255
+ K+ A + F P T P P ++ H++E +L+
Sbjct: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQ-HAAEIITDLLRS 345
Query: 256 ----------------GQSSG-LDASPPASTHELT--IPNDLIGCIIGRQGTKINEIRQM 296
G+ G + PP E +P G IIG+ G I I Q
Sbjct: 346 VQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQ 405
Query: 297 SGAQIKIANATEGSSE---RQITITGTPANISLAQYLINARLTSEVTGMG 343
SGA+I++ +++ + TI GTP I A+ LI ++ V +G
Sbjct: 406 SGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG 455
Score = 72.0 bits (175), Expect = 7e-13
Identities = 63/211 (29%), Positives = 94/211 (44%), Gaps = 40/211 (18%)
Query: 57 VGSIIGKKGETVKKMREESGARINIS--EGNCPERIVTITGPTDAIFKAFAMIAYKFEED 114
VG +IG+ GE +KK++ ++G RI +G PERI ITGP D A +I D
Sbjct: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIIT-----D 341
Query: 115 IINSM-SNSPA----------------TSKPPVTLR---LVVPASQCGSLIGKGGSKIKE 154
++ S+ + +P PP L+ +VP + G +IGKGG IK
Sbjct: 342 LLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKS 401
Query: 155 IRESTGAQVQVAGDMLPNS--TERAVTISGTPDAIIQCVKQI------CVVMLEAYTIQG 206
I + +GA++++ + PN+ + TI GTP I + I V L G
Sbjct: 402 ISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHG 461
Query: 207 QYAIPHPDLTKLHQLAMQQTPFPPLGQTNPA 237
+ +P P H P P+G NPA
Sbjct: 462 PHGVPGP-----HGPPGPPGPGTPMGPYNPA 487
Score = 57.0 bits (136), Expect = 2e-08
Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 11/113 (9%)
Query: 231 LGQTNPAFPGEKLPLHSSEE--AQNLMGQSSGLDASPP---------ASTHELTIPNDLI 279
L + + G+K PL ++ A+ + Q+ P T E +P+ ++
Sbjct: 53 LNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMV 112
Query: 280 GCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 332
G IIGR G +I+ I+Q SG +I+IA + G ER +TGTP ++ A+ L++
Sbjct: 113 GFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLD 165
Score = 48.5 bits (114), Expect = 9e-06
Identities = 46/212 (21%), Positives = 89/212 (41%), Gaps = 63/212 (29%)
Query: 126 SKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDM--LPNSTERAVTISGT 183
S+ +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ ++GT
Sbjct: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
Query: 184 PDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKL 243
P++ +Q K++ ++E G+ P F
Sbjct: 154 PES-VQSAKRLLDQIVEK------------------------------GRPAPGF----- 177
Query: 244 PLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI 303
H + P + E+ IP G +IG+ G I ++++ +G +K+
Sbjct: 178 --HHGD--------------GPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAG--VKM 219
Query: 304 ANATEG----SSERQITITGTPANISLAQYLI 331
+G +++ + ITG P + A+ ++
Sbjct: 220 VMIQDGPQNTGADKPLRITGDPYKVQQAKEMV 251
Score = 36.2 bits (82), Expect = 0.044
Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
Query: 56 EVGSIIGKKGETVKKMREESGARINISEGNCPE-----RIVTITGPTDAIFKAFAMIAYK 110
+ G IIGK GET+K + ++SGARI + P ++ TI G I A +I K
Sbjct: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 79.0 bits (193), Expect = 6e-15
Identities = 56/179 (31%), Positives = 93/179 (51%), Gaps = 23/179 (12%)
Query: 35 SKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN-----CPER 89
+K S G +++L+ GSIIGK G+T+ ++++E+GA I +S+ ER
Sbjct: 22 TKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTER 81
Query: 90 IVTITGPTDAIFKAFAMIAYKFEE--------DIINSMSNSPATSKPP---VTLRLVVPA 138
+ + G +A+ + IA K E +++N + P T+ P +L+VP
Sbjct: 82 VCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQ--PQTTMNPDRAKQAKLIVPN 139
Query: 139 SQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLP---NSTERAVTISGTPDAIIQCVKQI 194
S G +IGKGG+ +K + E +GA VQ++ P N ER VT+SG P+ + + V I
Sbjct: 140 STAGLIIGKGGATVKAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAI 196
Score = 68.6 bits (166), Expect = 8e-12
Identities = 48/200 (24%), Positives = 88/200 (44%), Gaps = 46/200 (23%)
Query: 132 LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQ 189
L++++P+ GS+IGKGG I ++++ TGA ++++ D P +TER + GT +A
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEA--- 91
Query: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSE 249
L +H ++ P T P
Sbjct: 92 -------------------------LNAVHSFIAEKVREIPQAMTKP------------- 113
Query: 250 EAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEG 309
E N++ + ++ A +L +PN G IIG+ G + + + SGA ++++ EG
Sbjct: 114 EVVNILQPQTTMNPDR-AKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEG 172
Query: 310 SS--ERQITITGTPANISLA 327
+ ER +T++G P + A
Sbjct: 173 INLQERVVTVSGEPEQVHKA 192
Score = 60.8 bits (146), Expect = 2e-09
Identities = 29/71 (40%), Positives = 49/71 (69%), Gaps = 3/71 (4%)
Query: 271 ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATE---GSSERQITITGTPANISLA 327
E+ +P +L+G I+G+ G + E ++++GA+I+I+ E G+ R++TITG+PA A
Sbjct: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
Query: 328 QYLINARLTSE 338
QYLI+ R+T E
Sbjct: 470 QYLISQRVTYE 480
Score = 55.8 bits (133), Expect = 5e-08
Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 17/118 (14%)
Query: 49 RLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKAF 104
+L++ G IIGK G TVK + E+SGA + +S+ N ER+VT++G + + KA
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
Query: 105 AMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGG 149
+ I K +ED + ++NS T P + V+PA+ S G
Sbjct: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
Score = 50.8 bits (120), Expect = 2e-06
Identities = 23/57 (40%), Positives = 39/57 (68%), Gaps = 2/57 (3%)
Query: 132 LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVA--GDMLPNSTERAVTISGTPDA 186
+ + VP + G+++GKGG + E +E TGA++Q++ G+ LP + R VTI+G+P A
Sbjct: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAA 465
Score = 33.9 bits (76), Expect = 0.22
Identities = 23/59 (38%), Positives = 34/59 (57%), Gaps = 5/59 (8%)
Query: 57 VGSIIGKKGETVKKMREESGARINISE-----GNCPERIVTITGPTDAIFKAFAMIAYK 110
VG+I+GK G+T+ + +E +GARI IS+ R VTITG A A +I+ +
Sbjct: 418 VGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQR 476
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 76.6 bits (187), Expect = 3e-14
Identities = 77/329 (23%), Positives = 136/329 (41%), Gaps = 81/329 (24%)
Query: 24 HPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINIS- 82
HP P+ E +V +G VG IIG+ GE + K++++SG ++ IS
Sbjct: 138 HPPPRTSMTEEYRVPDG---------------MVGLIIGRGGEQINKIQQDSGCKVQISP 182
Query: 83 -EGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATS--------KPPVTLR 133
G PER V++TG +++ KA M+ +DI++ P +
Sbjct: 183 DSGGLPERSVSLTGAPESVQKAKMML-----DDIVSRGRGGPPGQFHDNANGGQNGTVQE 237
Query: 134 LVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN-STERAVTISGTPDAIIQCVK 192
+++PA + G +IGKGG IK+++E G ++ + D N + ++ + I G P + Q +
Sbjct: 238 IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACE 297
Query: 193 QICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQ 252
+ ++ E QG + G++ +E
Sbjct: 298 MVMDILRE--RDQGGF-------------------------------GDR-----NEYGS 319
Query: 253 NLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSE 312
+ G G+D + +P +G +IGR G I +I+ +G +I+ E
Sbjct: 320 RIGG---GID---------VPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPE 367
Query: 313 RQITITGTPANISLAQYLINARLTSEVTG 341
+ I G P A +IN L S +G
Sbjct: 368 KIAHIMGPPDRCEHAARIINDLLQSLRSG 396
Score = 68.9 bits (167), Expect = 6e-12
Identities = 54/197 (27%), Positives = 87/197 (44%), Gaps = 39/197 (19%)
Query: 18 LSTLSHHPQPQFGRRME--SKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREES 75
+ L Q FG R E S++ GG++V + VG +IG+ GE +KK++ ++
Sbjct: 300 MDILRERDQGGFGDRNEYGSRIG-GGIDVPVPRH------SVGVVIGRSGEMIKKIQNDA 352
Query: 76 GARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPAT-------- 125
G RI + G PE+I I GP D A +I D++ S+ + P
Sbjct: 353 GVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARII-----NDLLQSLRSGPPGPPGGPGMP 407
Query: 126 -------------SKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN 172
P + +P +CG +IG+GG +K I + TGA V+++ + PN
Sbjct: 408 PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPN 467
Query: 173 STE--RAVTISGTPDAI 187
+ I G+P I
Sbjct: 468 GDPNFKLFIIRGSPQQI 484
Score = 67.0 bits (162), Expect = 2e-11
Identities = 75/314 (23%), Positives = 126/314 (40%), Gaps = 45/314 (14%)
Query: 38 SEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI----SEGNCPERIVTI 93
+ GG N T+ ++ GK G +IGK GET+K+++E +G ++ + S+ ++ + I
Sbjct: 227 ANGGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285
Query: 94 TGPTDAIFKAFAMIAYKFEE-DIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
G + +A M+ E D + S+ + + VP G +IG+ G I
Sbjct: 286 IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMI 345
Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPH 212
K+I+ G ++Q D E+ I G PD + I
Sbjct: 346 KKIQNDAGVRIQFKQDD-GTGPEKIAHIMGPPDRCEHAARII------------------ 386
Query: 213 PDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHEL 272
L Q P PP G P PG + G+ G + PP
Sbjct: 387 ---NDLLQSLRSGPPGPPGGPGMP--PGGRG-----------RGRGQG-NWGPPGGEMTF 429
Query: 273 TIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSE---RQITITGTPANISLAQY 329
+IP G +IGR G + I Q +GA ++I+ + + + I G+P I A+
Sbjct: 430 SIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQ 489
Query: 330 LINARLTSEVTGMG 343
LI ++ + +G
Sbjct: 490 LIEEKIEGPLCPVG 503
Score = 58.5 bits (140), Expect = 8e-09
Identities = 32/105 (30%), Positives = 60/105 (57%), Gaps = 10/105 (9%)
Query: 238 FPGEKLPLHSSE--EAQNLMGQSSGLDAS------PPAS--THELTIPNDLIGCIIGRQG 287
F G+K L + E++ L Q + + PP + T E +P+ ++G IIGR G
Sbjct: 105 FGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGG 164
Query: 288 TKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 332
+IN+I+Q SG +++I+ + G ER +++TG P ++ A+ +++
Sbjct: 165 EQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLD 209
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 75.9 bits (185), Expect = 5e-14
Identities = 66/300 (22%), Positives = 122/300 (40%), Gaps = 62/300 (20%)
Query: 55 KEVGSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFE 112
K VG IIG+ GE + +++ ESG +I I+ PER +TG ++I +A ++
Sbjct: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLG---- 142
Query: 113 EDIINSMSNSPA----TSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQ-VQVAG 167
I++ N P +++PAS+ G +IG+GG IK+++E TG + V +
Sbjct: 143 -QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQD 201
Query: 168 DMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTP 227
LP ++ + I+G + Q + + ++ E
Sbjct: 202 GPLPTGADKPLRITGDAFKVQQAREMVLEIIRE--------------------------- 234
Query: 228 FPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQG 287
++ + G ++ + E+++P +G +IGR G
Sbjct: 235 ---------------------KDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNG 273
Query: 288 TKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARL--TSEVTGMGTL 345
I +I+ +G +I+ S ER + G P A ++I+ + E G G L
Sbjct: 274 EMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGL 333
Score = 71.6 bits (174), Expect = 9e-13
Identities = 73/299 (24%), Positives = 124/299 (41%), Gaps = 53/299 (17%)
Query: 50 LLMHGKEVGSIIGKKGETVKKMREESGAR-INISEGNCP---ERIVTITGPTDAIFKAFA 105
+L+ +VG +IG+ GET+K+++E +G + + I +G P ++ + ITG + +A
Sbjct: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
Query: 106 M---IAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQ 162
M I + ++ + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
Query: 163 VQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLA 222
+Q D S ERA + G PD I ++L A
Sbjct: 287 IQFKPDD-GISPERAAQVMGPPDRCQHAAHIISELILTA--------------------- 324
Query: 223 MQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSG-LDASPPASTHEL--TIPNDLI 279
Q F G A G+ G P E+ T+P D
Sbjct: 325 ----------QERDGFGG--------LAAARGRGRGRGDWSVGAPGGVQEITYTVPADKC 366
Query: 280 GCIIGRQGTKINEIRQMSGAQIKIANATEGSSE---RQITITGTPANISLAQYLINARL 335
G +IG+ G I I Q SGA +++ +S+ R+ TI G P I +A+ LI+ ++
Sbjct: 367 GLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425
Score = 55.5 bits (132), Expect = 7e-08
Identities = 37/124 (29%), Positives = 60/124 (48%), Gaps = 12/124 (9%)
Query: 215 LTKLHQLAMQQTPFPPLGQTNP-------AFPGEKLPLHSSEEAQNLMGQSSGLDASPPA 267
L ++ Q+A + P L + P + +K PL + Q L
Sbjct: 23 LHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDG-----VGNQLGALVHQRTV 77
Query: 268 STHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLA 327
T E +P+ ++G IIGR G +I+ I+ SG +I+IA+ + G ER +TGTP +I A
Sbjct: 78 ITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQA 137
Query: 328 QYLI 331
+ L+
Sbjct: 138 KRLL 141
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 72.4 bits (176), Expect = 6e-13
Identities = 43/134 (32%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIFKAF 104
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R+V ITGP +A FKA
Sbjct: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
I K +E+ + + + VPAS G +IGKGG + E++ T A+V
Sbjct: 329 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
Query: 165 VAGDMLPNSTERAV 178
V D P+ ++ +
Sbjct: 384 VPRDQTPDENDQVI 397
Score = 61.6 bits (148), Expect = 1e-09
Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 45/184 (24%)
Query: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN-----CPERIVTITGPTDAIFK 102
+++L H VG +IGK+G +KK+ +++ +I IS PER +T+ G + +
Sbjct: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
Query: 103 AFAMIAYKFEEDIINSM----------------------SNSPATSKPPVT--------- 131
A I K E N + ++S A PP +
Sbjct: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
Query: 132 ---------LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISG 182
+++ +PA G++IGK G IK++ A +++A P+S R V I+G
Sbjct: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
Query: 183 TPDA 186
P+A
Sbjct: 320 PPEA 323
Score = 59.7 bits (143), Expect = 4e-09
Identities = 51/213 (23%), Positives = 90/213 (42%), Gaps = 16/213 (7%)
Query: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAI 187
V L+++ + G LIGK G +K++ + T ++ ++ D+ + ER +T+ G +
Sbjct: 138 VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENC 197
Query: 188 IQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPA-FPGEKLPLH 246
+ ++I + EAY + +++Q P L FP +
Sbjct: 198 CRAEQEIMKKVREAYE------------NDVAAMSLQSHLIPGLNLAAVGLFPASSSAVP 245
Query: 247 SSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA-N 305
+ S +P ++ IP +G IIG++G I ++ + + A IKIA
Sbjct: 246 PPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPP 305
Query: 306 ATEGSSERQITITGTPANISLAQYLINARLTSE 338
T S R + ITG P AQ I +L E
Sbjct: 306 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 338
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 57.8 bits (138), Expect = 1e-08
Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 21/143 (14%)
Query: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI-SEGNCPERIVTITGPTDAIFKAF 104
+ I + + + V IIG++G +K++R+++GARI++ +E ER++ I+G + KA
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQV- 163
A I + T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 113 AAI-------------HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159
Query: 164 ---QVAGDMLPNSTERAVTISGT 183
+ G +L R + ISGT
Sbjct: 160 CDKESEGTLL---LSRLIKISGT 179
Score = 51.2 bits (121), Expect = 1e-06
Identities = 49/211 (23%), Positives = 83/211 (39%), Gaps = 68/211 (32%)
Query: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
+ + + VP +IG+ G+ IK++R+ TGA++ V D ER + ISG P
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISGFP----- 105
Query: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSE 249
Q+C +HQ+ + TP
Sbjct: 106 --VQVCKAK-----------------AAIHQILTENTPV--------------------- 125
Query: 250 EAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEG 309
+ +L++P +G IIGR G I I + SGA+I +EG
Sbjct: 126 -------------------SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEG 166
Query: 310 S--SERQITITGTPANISLAQYLINARLTSE 338
+ R I I+GT ++ A++LI +++ +
Sbjct: 167 TLLLSRLIKISGTQKEVAAAKHLILEKVSED 197
Score = 38.1 bits (87), Expect = 0.012
Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 9/100 (9%)
Query: 43 NVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGN-CPERIVTITGPTD 98
N ++ +L + + VG IIG+ GET++ + + SGA+I SEG R++ I+G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 99 AIFKAFAMIAYKFEED--IINSMSNSPATSKP---PVTLR 133
+ A +I K ED + +++S T P P+++R
Sbjct: 182 EVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVR 221
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 57.8 bits (138), Expect = 1e-08
Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 21/143 (14%)
Query: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI-SEGNCPERIVTITGPTDAIFKAF 104
+ I + + + V IIG++G +K++R+++GARI++ +E ER++ I+G + KA
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQV- 163
A I + T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 113 AAI-------------HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159
Query: 164 ---QVAGDMLPNSTERAVTISGT 183
+ G +L R + ISGT
Sbjct: 160 CDKESEGTLL---LSRLIKISGT 179
Score = 51.2 bits (121), Expect = 1e-06
Identities = 49/211 (23%), Positives = 83/211 (39%), Gaps = 68/211 (32%)
Query: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
+ + + VP +IG+ G+ IK++R+ TGA++ V D ER + ISG P
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISGFP----- 105
Query: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSE 249
Q+C +HQ+ + TP
Sbjct: 106 --VQVCKAK-----------------AAIHQILTENTPV--------------------- 125
Query: 250 EAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEG 309
+ +L++P +G IIGR G I I + SGA+I +EG
Sbjct: 126 -------------------SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEG 166
Query: 310 S--SERQITITGTPANISLAQYLINARLTSE 338
+ R I I+GT ++ A++LI +++ +
Sbjct: 167 TLLLSRLIKISGTQKEVAAAKHLILEKVSED 197
Score = 38.1 bits (87), Expect = 0.012
Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 9/100 (9%)
Query: 43 NVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGN-CPERIVTITGPTD 98
N ++ +L + + VG IIG+ GET++ + + SGA+I SEG R++ I+G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 99 AIFKAFAMIAYKFEED--IINSMSNSPATSKP---PVTLR 133
+ A +I K ED + +++S T P P+++R
Sbjct: 182 EVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVR 221
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 57.8 bits (138), Expect = 1e-08
Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 21/143 (14%)
Query: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI-SEGNCPERIVTITGPTDAIFKAF 104
+ I + + + V IIG++G +K++R+++GARI++ +E ER++ I+G + KA
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQV- 163
A I + T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 113 AAI-------------HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159
Query: 164 ---QVAGDMLPNSTERAVTISGT 183
+ G +L R + ISGT
Sbjct: 160 CDKESEGTLL---LSRLIKISGT 179
Score = 51.2 bits (121), Expect = 1e-06
Identities = 49/211 (23%), Positives = 83/211 (39%), Gaps = 68/211 (32%)
Query: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
+ + + VP +IG+ G+ IK++R+ TGA++ V D ER + ISG P
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISGFP----- 105
Query: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSE 249
Q+C +HQ+ + TP
Sbjct: 106 --VQVCKAK-----------------AAIHQILTENTPV--------------------- 125
Query: 250 EAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEG 309
+ +L++P +G IIGR G I I + SGA+I +EG
Sbjct: 126 -------------------SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEG 166
Query: 310 S--SERQITITGTPANISLAQYLINARLTSE 338
+ R I I+GT ++ A++LI +++ +
Sbjct: 167 TLLLSRLIKISGTQKEVAAAKHLILEKVSED 197
Score = 38.1 bits (87), Expect = 0.012
Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 9/100 (9%)
Query: 43 NVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGN-CPERIVTITGPTD 98
N ++ +L + + VG IIG+ GET++ + + SGA+I SEG R++ I+G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 99 AIFKAFAMIAYKFEED--IINSMSNSPATSKP---PVTLR 133
+ A +I K ED + +++S T P P+++R
Sbjct: 182 EVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVR 221
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,520,317
Number of Sequences: 37866
Number of extensions: 623754
Number of successful extensions: 1981
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 1537
Number of HSP's gapped (non-prelim): 278
length of query: 345
length of database: 18,247,518
effective HSP length: 103
effective length of query: 242
effective length of database: 14,347,320
effective search space: 3472051440
effective search space used: 3472051440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.