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Search of human proteins with 194272210
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194272210 lysyl-tRNA synthetase isoform 1 [Homo sapiens]
(625 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194272210 lysyl-tRNA synthetase isoform 1 [Homo sapiens] 1269 0.0
gi|5031815 lysyl-tRNA synthetase isoform 2 [Homo sapiens] 1171 0.0
gi|45439306 aspartyl-tRNA synthetase [Homo sapiens] 81 3e-15
gi|40789249 aspartyl-tRNA synthetase 2, mitochondrial [Homo sapi... 75 2e-13
gi|226491502 asparaginyl-tRNA synthetase 2, mitochondrial [Homo ... 46 1e-04
gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens] 44 3e-04
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 36 0.12
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s... 33 0.60
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s... 33 0.60
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 33 1.0
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 32 1.3
gi|153791707 sorting nexin family member 30 [Homo sapiens] 32 1.3
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 32 1.8
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 32 1.8
gi|53759141 zinc finger protein 32 [Homo sapiens] 32 1.8
gi|24307925 zinc finger protein 32 [Homo sapiens] 32 1.8
gi|54607116 leiomodin 3 (fetal) [Homo sapiens] 32 2.3
gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens] 32 2.3
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 31 3.0
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 31 3.0
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 31 3.0
gi|11276067 snail 2 [Homo sapiens] 31 3.9
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 31 3.9
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 31 3.9
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 31 3.9
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens] 31 3.9
gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens] 31 3.9
gi|142976783 PDZ domain containing RING finger 4 [Homo sapiens] 31 3.9
gi|23238244 sorting nexin 16 isoform a [Homo sapiens] 31 3.9
gi|23238246 sorting nexin 16 isoform a [Homo sapiens] 31 3.9
>gi|194272210 lysyl-tRNA synthetase isoform 1 [Homo sapiens]
Length = 625
Score = 1269 bits (3283), Expect = 0.0
Identities = 625/625 (100%), Positives = 625/625 (100%)
Query: 1 MLTQAAVRLVRGSLRKTSWAEWGHRELRLGQLAPFTAPHKDKSFSDQRSELKRRLKAEKK 60
MLTQAAVRLVRGSLRKTSWAEWGHRELRLGQLAPFTAPHKDKSFSDQRSELKRRLKAEKK
Sbjct: 1 MLTQAAVRLVRGSLRKTSWAEWGHRELRLGQLAPFTAPHKDKSFSDQRSELKRRLKAEKK 60
Query: 61 VAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVDPNQYYKIRSQAIHQLKVNGE 120
VAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVDPNQYYKIRSQAIHQLKVNGE
Sbjct: 61 VAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVDPNQYYKIRSQAIHQLKVNGE 120
Query: 121 DPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGV 180
DPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGV
Sbjct: 121 DPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGV 180
Query: 181 KLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHM 240
KLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHM
Sbjct: 181 KLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHM 240
Query: 241 LPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMN 300
LPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMN
Sbjct: 241 LPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMN 300
Query: 301 IIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHN 360
IIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHN
Sbjct: 301 IIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHN 360
Query: 361 PEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFR 420
PEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFR
Sbjct: 361 PEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFR 420
Query: 421 RINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFL 480
RINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFL
Sbjct: 421 RINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFL 480
Query: 481 EVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLF 540
EVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLF
Sbjct: 481 EVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLF 540
Query: 541 EEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPA 600
EEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPA
Sbjct: 541 EEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPA 600
Query: 601 MKPEDKKENVATTDTLESTTVGTSV 625
MKPEDKKENVATTDTLESTTVGTSV
Sbjct: 601 MKPEDKKENVATTDTLESTTVGTSV 625
>gi|5031815 lysyl-tRNA synthetase isoform 2 [Homo sapiens]
Length = 597
Score = 1171 bits (3030), Expect = 0.0
Identities = 576/578 (99%), Positives = 578/578 (100%)
Query: 48 RSELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVDPNQYYKI 107
++ELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVDPNQYYKI
Sbjct: 20 KNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVDPNQYYKI 79
Query: 108 RSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASG 167
RSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASG
Sbjct: 80 RSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASG 139
Query: 168 GKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSII 227
GKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSII
Sbjct: 140 GKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSII 199
Query: 228 PYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLD 287
PYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLD
Sbjct: 200 PYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLD 259
Query: 288 ELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIG 347
ELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIG
Sbjct: 260 ELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIG 319
Query: 348 RQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPE 407
RQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPE
Sbjct: 320 RQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPE 379
Query: 408 GQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRT 467
GQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRT
Sbjct: 380 GQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRT 439
Query: 468 TARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAY 527
TARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAY
Sbjct: 440 TARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAY 499
Query: 528 TELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLT 587
TELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLT
Sbjct: 500 TELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLT 559
Query: 588 DSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV 625
DSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV
Sbjct: 560 DSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV 597
>gi|45439306 aspartyl-tRNA synthetase [Homo sapiens]
Length = 501
Score = 80.9 bits (198), Expect = 3e-15
Identities = 106/475 (22%), Positives = 193/475 (40%), Gaps = 64/475 (13%)
Query: 151 DITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDII 210
D + V R+H RA G K F LR + +Q + ++ S++ + + + I+
Sbjct: 57 DEVVWVRARVHTSRAKG-KQCFLVLRQQQFNVQALVAVGDHASKQ-MVKFAANINKESIV 114
Query: 211 GVQGNPGKTKKGELSIIPYEITLLSPCLHML----PHLHFGLKD---------------- 250
V+G K + S ++ L ++++ P L L D
Sbjct: 115 DVEGVVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAVRPEAEGEEEGRATV 174
Query: 251 -KETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAK 309
++TR R +DL + + F ++S I R L GF+EI+TP + A
Sbjct: 175 NQDTRLDNRVIDLRTSTS-QAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGAN 233
Query: 310 PF-ITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDL-THNPEFTTCE 367
F ++Y N Y+ +P+LY +M + ++V+ IG FR E + H EF +
Sbjct: 234 VFTVSYFKN---NAYLAQSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLD 290
Query: 368 FYMAYA-DYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVE 426
MA+ YH++ME + + K + ++ + F P R+ E
Sbjct: 291 IEMAFNYHYHEVMEEIADTMVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCE 350
Query: 427 ELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCIN 486
AL M L E + +E DD+ +KL+G ++
Sbjct: 351 ----ALAM-LREAGVEMGDE-----DDLSTPN--------------EKLLGHLVKEKYDT 386
Query: 487 PTFICD-HPQIMSPLAKWHRSKEGL-TERFELFVMKKEICNAYTELNDPMRQRQLFEEQA 544
+I D +P + P + + +++F+ +EI + ++DP QL E+A
Sbjct: 387 DFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDP----QLLTERA 442
Query: 545 KAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 599
++ ++F +G PP AG G+G++RV M +N+++ +FP
Sbjct: 443 LHHGIDLEKIKAYIDSF----RFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFP 493
>gi|40789249 aspartyl-tRNA synthetase 2, mitochondrial [Homo
sapiens]
Length = 645
Score = 74.7 bits (182), Expect = 2e-13
Identities = 56/178 (31%), Positives = 94/178 (52%), Gaps = 9/178 (5%)
Query: 213 QGNPGKTKKGELSIIPYEITLLSPCLHMLPHL-HFGLKDKETRYRQRYLDLILNDFVRQK 271
Q NP K GE+ I LL+ C + + +F K + R + RYLDL F Q
Sbjct: 129 QENP-KMPTGEIEIKVKTAELLNACKKLPFEIKNFVKKTEALRLQYRYLDL--RSFQMQY 185
Query: 272 FI-IRSKIITYIRSFLDEL-GFLEIETP-MMNIIPGGAVAKPFITYHNELDMNLYMRIAP 328
+ +RS+++ +R +L L GF++IETP + PGGA K F+ E + +P
Sbjct: 186 NLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGA--KEFLVPSREPGKFYSLPQSP 243
Query: 329 ELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMV 386
+ + ++L+VGG+DR +++ R +R+EG PEFT + M++ D + + E ++
Sbjct: 244 QQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQSLIEGLL 301
Score = 43.1 bits (100), Expect = 8e-04
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 9/119 (7%)
Query: 481 EVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLF 540
E+ + F HP + L + K+ ++ ++L + EI +++ QR +
Sbjct: 496 ELESAHHPFTAPHPSDIHLL--YTEPKKARSQHYDLVLNGNEIGGGSIRIHNAELQRYIL 553
Query: 541 EEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 599
K +D M + AL+YG PP G +G+DR+ +T S +I++V+ FP
Sbjct: 554 ATLLK-----EDVKML--SHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIAFP 605
>gi|226491502 asparaginyl-tRNA synthetase 2, mitochondrial [Homo
sapiens]
Length = 477
Score = 45.8 bits (107), Expect = 1e-04
Identities = 97/469 (20%), Positives = 170/469 (36%), Gaps = 86/469 (18%)
Query: 177 GEGVKLQVMANSRNYKSEEEFIHINN------------------KLRRGDIIGVQGNPGK 218
GE +K+Q S + E F+H+N+ +L G + VQG K
Sbjct: 41 GERIKIQGWIRSVRSQKEVLFLHVNDGSSLESLQVVADSGLDSRELNFGSSVEVQGQLIK 100
Query: 219 T--KKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQK----- 271
+ K+ + + +I ++ C KD +Y++R+ L + +
Sbjct: 101 SPSKRQNVELKAEKIKVIGNC---------DAKDFPIKYKERHPLEYLRQYPHFRCRTNV 151
Query: 272 ----FIIRSKIITYIRSFLDELGFLEIETP------------MMNIIPGGAVAKPFITYH 315
IRS+ I SF + GF+ I TP + + P G + P
Sbjct: 152 LGSILRIRSEATAAIHSFFKDSGFVHIHTPIITSNDSEGAGELFQLEPSGKLKVP---EE 208
Query: 316 NELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGI-DLTHNPEFTTCEFYMAYAD 374
N ++ ++ ++ +L H ++ G +V+ G FR E H EF E +++ D
Sbjct: 209 NFFNVPAFLTVSGQL-HLEVMSGAFTQVFTFGPTFRAENSQSRRHLAEFYMIEAEISFVD 267
Query: 375 -YHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALG 433
DLM++ E++ + PE DV+ F + LE L
Sbjct: 268 SLQDLMQVIEELFKATTMMVLSKC--------PE----DVELCHKFIAPGQKDRLEHMLK 315
Query: 434 MKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCIN-PTFICD 492
+ E E K RT ++L C N P F+ +
Sbjct: 316 NNFLIISYTEAVEILKQASQNFTFTPEWGADLRTEHE-------KYLVKHCGNIPVFVIN 368
Query: 493 HPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTEL--NDPMRQRQLFEEQAKAKAAG 550
+P + P + R E + V + EL +R F E+ A++
Sbjct: 369 YPLTLKPF--YMRDNEDGPQHTVAAV--DLLVPGVGELFGGGLREERYHFLEERLARSGL 424
Query: 551 DDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 599
+ + + + +G P G+GMG +R + +NIK+V+ FP
Sbjct: 425 TE----VYQWYLDLRRFGSVPHGGFGMGFERYLQCILGVDNIKDVIPFP 469
>gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens]
Length = 548
Score = 44.3 bits (103), Expect = 3e-04
Identities = 104/465 (22%), Positives = 177/465 (38%), Gaps = 71/465 (15%)
Query: 154 LKVAGRIHAKRASGGKLIFYDLR-GEGVKLQVMANSRNYKSEEEFIHINNK--LRRGDII 210
+KV G +H R G L+F LR G G V+A +E N L +
Sbjct: 128 VKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLA--------DELCQCYNGVLLSTESSV 179
Query: 211 GVQGNPGKTKKG-------ELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLI 263
V G T KG ELS +E+ L+P +L D + + R++ +I
Sbjct: 180 AVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPA-GGADNLINEESDVDVQLNNRHM-MI 237
Query: 264 LNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDMN 321
+ + + RS + R + G+ E+ P + + GGA + E
Sbjct: 238 RGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEA--- 294
Query: 322 LYMRIAPELYHKMLVVGGIDRVYEIGRQFRNE-GIDLTHNPEFTTCEFYMAYADYHDLME 380
++ + +LY + + + V+ I + +R E H E+T E + + DL+
Sbjct: 295 -FLTQSSQLYLETCLPA-LGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLN 352
Query: 381 ITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTP---PFRRINMVEELE--KALGMK 435
E +V +V I S P G + +F P PF+R+N + + K +K
Sbjct: 353 RLEDLVCDVVDRILKS------PAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVK 406
Query: 436 LPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHP- 494
+ +E E DI P RL+ + E P +C P
Sbjct: 407 KEDGTFYEFGE------DI----------PEAPERLMTDTINE--------PILLCRFPV 442
Query: 495 QIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEA 554
+I S + LTE ++ + N + MR E A K G D
Sbjct: 443 EIKSFYMQRCPEDSRLTESVDVLMP-----NVGEIVGGSMRIFDSEEILAGYKREGIDPT 497
Query: 555 MFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 599
+ + +YG P G+G+G++R ++ + +I++V L+P
Sbjct: 498 PYY--WYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYP 540
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 35.8 bits (81), Expect = 0.12
Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 47 QRSELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVDPNQYYK 106
+R E+K++LK KK +KE K+K+ E++ + T + T + +E ++
Sbjct: 220 RRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHN---KERRSKRDEKLD 276
Query: 107 IRSQAIHQLKVNGE 120
+SQA+ +LK E
Sbjct: 277 KKSQAMEELKAERE 290
>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
sapiens]
Length = 732
Score = 33.5 bits (75), Expect = 0.60
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 19/130 (14%)
Query: 35 FTAPHKDKSFSDQRSELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGP 94
F +DK SD +E K + EK+ EKE++ K E D G
Sbjct: 221 FVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIE---------------DVGSDE 265
Query: 95 EEESV--DPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPG--DHLT 150
EEE D + KI+ + I Q ++N P + DI+ ++ + Y L DHL
Sbjct: 266 EEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLA 325
Query: 151 DITLKVAGRI 160
V G++
Sbjct: 326 VKHFSVEGQL 335
>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
sapiens]
Length = 854
Score = 33.5 bits (75), Expect = 0.60
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 19/130 (14%)
Query: 35 FTAPHKDKSFSDQRSELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGP 94
F +DK SD +E K + EK+ EKE++ K E D G
Sbjct: 343 FVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIE---------------DVGSDE 387
Query: 95 EEESV--DPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPG--DHLT 150
EEE D + KI+ + I Q ++N P + DI+ ++ + Y L DHL
Sbjct: 388 EEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLA 447
Query: 151 DITLKVAGRI 160
V G++
Sbjct: 448 VKHFSVEGQL 457
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 32.7 bits (73), Expect = 1.0
Identities = 20/78 (25%), Positives = 34/78 (43%), Gaps = 7/78 (8%)
Query: 39 HKDKSFSDQRSELKRRLKAEKKVAEKEAKQKE------LSEKQLSQATAAATNHTTDNGV 92
HK+K ++ + K + K+ K +K K+KE K+ + A NG
Sbjct: 851 HKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAGEPVQNG- 909
Query: 93 GPEEESVDPNQYYKIRSQ 110
PEEE + P Y + ++
Sbjct: 910 APEEEQLPPESSYSLLAE 927
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 32.3 bits (72), Expect = 1.3
Identities = 23/99 (23%), Positives = 49/99 (49%), Gaps = 6/99 (6%)
Query: 34 PFTAPHKDKSFSDQRSELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVG 93
P P +D+ Q+ R++K ++ + E K +S+++ A AA + ++
Sbjct: 733 PSPPPEEDEDPGVQKRRSSRQVKRKRYTEDLEFK---ISDEEADDADAAGRDSPSNTSQS 789
Query: 94 PEEESVD---PNQYYKIRSQAIHQLKVNGEDPYPHKFHV 129
++ESVD P + S+++ + K +GE+ +F+V
Sbjct: 790 EQQESVDAEGPVVEKIMSSRSVKKQKESGEEVEIEEFYV 828
>gi|153791707 sorting nexin family member 30 [Homo sapiens]
Length = 437
Score = 32.3 bits (72), Expect = 1.3
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 11/99 (11%)
Query: 316 NELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGID-----LTHNPEFTTCEFYM 370
++L+ + + P L K +V G +DR E + R + +D +T +P + E +
Sbjct: 141 SKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFN 200
Query: 371 AYADYHDLMEITEKMVSGM------VKHITGSYKVTYHP 403
+ DL ++ ++ + VKH+TG YK+ P
Sbjct: 201 IFLTAKDLNAYKKQGIALLTRMGESVKHVTGGYKLRTRP 239
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 32.0 bits (71), Expect = 1.8
Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 11/102 (10%)
Query: 8 RLVRGSLRKTSWAEWGHRELRLGQLAPFTAPHKDKSFSDQRSELKRRLKAEKKVAEK--- 64
RLV L +TS+ L+ ++ + HK+K ++ L+ R E K+ +K
Sbjct: 1046 RLVNDDLMQTSFERM--LSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKT 1103
Query: 65 -----EAKQKELSEKQLSQATAAATNH-TTDNGVGPEEESVD 100
E+K KEL+ + S+ T A T + V +SVD
Sbjct: 1104 KHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVD 1145
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 32.0 bits (71), Expect = 1.8
Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 11/102 (10%)
Query: 8 RLVRGSLRKTSWAEWGHRELRLGQLAPFTAPHKDKSFSDQRSELKRRLKAEKKVAEK--- 64
RLV L +TS+ L+ ++ + HK+K ++ L+ R E K+ +K
Sbjct: 1069 RLVNDDLMQTSFERM--LSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKT 1126
Query: 65 -----EAKQKELSEKQLSQATAAATNH-TTDNGVGPEEESVD 100
E+K KEL+ + S+ T A T + V +SVD
Sbjct: 1127 KHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVD 1168
>gi|53759141 zinc finger protein 32 [Homo sapiens]
Length = 273
Score = 32.0 bits (71), Expect = 1.8
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 9/102 (8%)
Query: 24 HRELRLGQLAPFTAPHKDKSFSDQRSELKRRLKAEKKV--AEKEAKQKELSEKQLSQATA 81
H + GQ PF H KSF K L +++ EK + KE K SQ +
Sbjct: 95 HERIHTGQ-KPFECTHCGKSF-----RAKGNLVTHQRIHTGEKPYQCKECG-KSFSQRGS 147
Query: 82 AATNHTTDNGVGPEEESVDPNQYYKIRSQAIHQLKVNGEDPY 123
A + G P E ++ + + A+H+ +GE PY
Sbjct: 148 LAVHERLHTGQKPYECAICQRSFRNQSNLAVHRRVHSGEKPY 189
>gi|24307925 zinc finger protein 32 [Homo sapiens]
Length = 273
Score = 32.0 bits (71), Expect = 1.8
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 9/102 (8%)
Query: 24 HRELRLGQLAPFTAPHKDKSFSDQRSELKRRLKAEKKV--AEKEAKQKELSEKQLSQATA 81
H + GQ PF H KSF K L +++ EK + KE K SQ +
Sbjct: 95 HERIHTGQ-KPFECTHCGKSF-----RAKGNLVTHQRIHTGEKPYQCKECG-KSFSQRGS 147
Query: 82 AATNHTTDNGVGPEEESVDPNQYYKIRSQAIHQLKVNGEDPY 123
A + G P E ++ + + A+H+ +GE PY
Sbjct: 148 LAVHERLHTGQKPYECAICQRSFRNQSNLAVHRRVHSGEKPY 189
>gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
Length = 560
Score = 31.6 bits (70), Expect = 2.3
Identities = 23/104 (22%), Positives = 49/104 (47%), Gaps = 11/104 (10%)
Query: 41 DKSFSDQRSELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVD 100
DK+F +QR + + ++EKK+++ + K+ L L +T + N T +G D
Sbjct: 193 DKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKND 252
Query: 101 PNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQ 144
P+ + +L +N + P + +D + ++K H++
Sbjct: 253 PD---------MKELNLNNIENIPKEMLLD--FVNAMKKNKHIK 285
>gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens]
Length = 809
Score = 31.6 bits (70), Expect = 2.3
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 9/60 (15%)
Query: 50 ELKRRLKAEKKV---------AEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEESVD 100
+LKR A+KK E E KQKE +KQ N D G PEE+ +D
Sbjct: 693 KLKREQAAQKKENSEGGEEEGKENEDKQKENEDKQKENEDKGKENEDKDKGREPEEKPLD 752
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 31.2 bits (69), Expect = 3.0
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 375 YHDLMEITEKMVSGMVKH--ITGSYKVTYHPDGPE-GQAYDVDFTPPFRRINMVEELEKA 431
Y ME+TE+++ ++K +T S T P E G + ++F+P R I + +
Sbjct: 623 YEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYLEQ 682
Query: 432 LGMKLPE 438
LG +PE
Sbjct: 683 LGFTVPE 689
>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
sapiens]
Length = 2517
Score = 31.2 bits (69), Expect = 3.0
Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 5/64 (7%)
Query: 8 RLVRGSLRKTSWAEWGHRELRLGQLAPFTAPHKDKSFSDQRSELKRRLKAEKKVAEKEAK 67
RL + L+ S +E R+ L QL DK F +Q E ++RL+ E++ E+E
Sbjct: 1628 RLPQLMLQSLSTSEELQRQFHLFQLQRL-----DKLFLEQEDEEEKRLEEEEEEEEEEEA 1682
Query: 68 QKEL 71
+KEL
Sbjct: 1683 EKEL 1686
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 31.2 bits (69), Expect = 3.0
Identities = 19/79 (24%), Positives = 35/79 (44%)
Query: 38 PHKDKSFSDQRSELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTTDNGVGPEEE 97
P+++ SF + K K + K++ Q E E+Q+ + A + +N E+E
Sbjct: 1007 PNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKE 1066
Query: 98 SVDPNQYYKIRSQAIHQLK 116
+ + K + I QLK
Sbjct: 1067 HKNQDDLLKEKETLIQQLK 1085
>gi|11276067 snail 2 [Homo sapiens]
Length = 268
Score = 30.8 bits (68), Expect = 3.9
Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 2/65 (3%)
Query: 3 TQAAVRLVRGSLRKTSWAEWGHRELRLGQLAPFTAPHKDKSFSDQRSELKRRLKAEKKVA 62
T V + G W GH G+ PF+ PH +++F+D RS L+ L+ V
Sbjct: 182 TLPCVCKICGKAFSRPWLLQGHIRTHTGE-KPFSCPHCNRAFAD-RSNLRAHLQTHSDVK 239
Query: 63 EKEAK 67
+ + K
Sbjct: 240 KYQCK 244
>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
Length = 558
Score = 30.8 bits (68), Expect = 3.9
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 7/58 (12%)
Query: 48 RSELKRRLKAEKKVAEK-------EAKQKELSEKQLSQATAAATNHTTDNGVGPEEES 98
R+ +++RLK EKK K E K++E +E+ L QA + + ++ + PE E+
Sbjct: 475 RAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDSLRVLNDSLTPEIEA 532
>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
Length = 706
Score = 30.8 bits (68), Expect = 3.9
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 7/58 (12%)
Query: 48 RSELKRRLKAEKKVAEK-------EAKQKELSEKQLSQATAAATNHTTDNGVGPEEES 98
R+ +++RLK EKK K E K++E +E+ L QA + + ++ + PE E+
Sbjct: 623 RAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDSLRVLNDSLTPEIEA 680
>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
Length = 504
Score = 30.8 bits (68), Expect = 3.9
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 7/58 (12%)
Query: 48 RSELKRRLKAEKKVAEK-------EAKQKELSEKQLSQATAAATNHTTDNGVGPEEES 98
R+ +++RLK EKK K E K++E +E+ L QA + + ++ + PE E+
Sbjct: 421 RAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDSLRVLNDSLTPEIEA 478
>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
Length = 1012
Score = 30.8 bits (68), Expect = 3.9
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Query: 580 DRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLES 618
D+ LTDS N +LLFP+MKP + E D +++
Sbjct: 194 DKYTTLLTDSEN--RLLLFPSMKPNKRVEVAQLNDVMDT 230
>gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]
Length = 938
Score = 30.8 bits (68), Expect = 3.9
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Query: 580 DRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLES 618
D+ LTDS N +LLFP+MKP + E D +++
Sbjct: 194 DKYTTLLTDSEN--RLLLFPSMKPNKRVEVAQLNDVMDT 230
>gi|142976783 PDZ domain containing RING finger 4 [Homo sapiens]
Length = 778
Score = 30.8 bits (68), Expect = 3.9
Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 12/66 (18%)
Query: 46 DQRSELKRRLKAEKKVAE------------KEAKQKELSEKQLSQATAAATNHTTDNGVG 93
D+R+E L E E ++ K++E E AT+++ NH D+GVG
Sbjct: 239 DERNEFLEELNLEMLEEEHNEAMQPTANEVEQPKKQEEEEGTTDTATSSSNNHEKDSGVG 298
Query: 94 PEEESV 99
+ES+
Sbjct: 299 RTDESL 304
>gi|23238244 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 30.8 bits (68), Expect = 3.9
Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 34 PFTAPHKDKSFSDQRSELKRRLKAE--KKVAEKEAKQKELSEKQLSQATAAATNHTTDNG 91
PF + + ++F + E RL+ E +K E E+ +K LSEKQL T N
Sbjct: 219 PFDSLEESRAFCETLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDT--LENRIRTLS 276
Query: 92 VGPEE----ESVDPNQYYKIRSQAI 112
+ PEE + Q K+ S A+
Sbjct: 277 LEPEESLDVSETEGEQILKVESSAL 301
>gi|23238246 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 30.8 bits (68), Expect = 3.9
Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 34 PFTAPHKDKSFSDQRSELKRRLKAE--KKVAEKEAKQKELSEKQLSQATAAATNHTTDNG 91
PF + + ++F + E RL+ E +K E E+ +K LSEKQL T N
Sbjct: 219 PFDSLEESRAFCETLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDT--LENRIRTLS 276
Query: 92 VGPEE----ESVDPNQYYKIRSQAI 112
+ PEE + Q K+ S A+
Sbjct: 277 LEPEESLDVSETEGEQILKVESSAL 301
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,186,465
Number of Sequences: 37866
Number of extensions: 1098641
Number of successful extensions: 4420
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 4323
Number of HSP's gapped (non-prelim): 112
length of query: 625
length of database: 18,247,518
effective HSP length: 108
effective length of query: 517
effective length of database: 14,157,990
effective search space: 7319680830
effective search space used: 7319680830
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.