BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|194272148 epsin 1 isoform a [Homo sapiens] (662 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|194272148 epsin 1 isoform a [Homo sapiens] 1363 0.0 gi|41350201 epsin 1 isoform c [Homo sapiens] 1131 0.0 gi|194248095 epsin 1 isoform b [Homo sapiens] 1123 0.0 gi|156671217 epsin 2 isoform a [Homo sapiens] 488 e-138 gi|157388929 epsin 3 [Homo sapiens] 414 e-115 gi|156671215 epsin 2 isoform b [Homo sapiens] 410 e-114 gi|31377575 ENTH domain containing 1 [Homo sapiens] 211 1e-54 gi|156671219 epsin 2 isoform c [Homo sapiens] 189 7e-48 gi|7661968 epsin 4 [Homo sapiens] 169 6e-42 gi|163965366 nascent polypeptide-associated complex alpha subuni... 92 2e-18 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 79 1e-14 gi|110832843 TBP-associated factor 4 [Homo sapiens] 74 3e-13 gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 72 1e-12 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 72 2e-12 gi|116284392 mucin 2 precursor [Homo sapiens] 72 2e-12 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 72 2e-12 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 71 3e-12 gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 70 6e-12 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 69 1e-11 gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 69 1e-11 gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho... 69 1e-11 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 69 2e-11 gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 68 3e-11 gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 68 3e-11 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 67 4e-11 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 67 4e-11 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 67 4e-11 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 67 4e-11 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 67 4e-11 gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 67 5e-11 >gi|194272148 epsin 1 isoform a [Homo sapiens] Length = 662 Score = 1363 bits (3528), Expect = 0.0 Identities = 662/662 (100%), Positives = 662/662 (100%) Query: 1 MGDQSWLWNQAAPGVRSPVFACSVEKGNVPLVLSEHLAHSRDPGSGAVRFLISPEPWASA 60 MGDQSWLWNQAAPGVRSPVFACSVEKGNVPLVLSEHLAHSRDPGSGAVRFLISPEPWASA Sbjct: 1 MGDQSWLWNQAAPGVRSPVFACSVEKGNVPLVLSEHLAHSRDPGSGAVRFLISPEPWASA 60 Query: 61 ILGTSGLLASPVLPAALDAVTCQHLPQPSSGSRPISPRIGALCPLLLQPGTMSTSSLRRQ 120 ILGTSGLLASPVLPAALDAVTCQHLPQPSSGSRPISPRIGALCPLLLQPGTMSTSSLRRQ Sbjct: 61 ILGTSGLLASPVLPAALDAVTCQHLPQPSSGSRPISPRIGALCPLLLQPGTMSTSSLRRQ 120 Query: 121 MKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGK 180 MKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGK Sbjct: 121 MKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGK 180 Query: 181 NWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQ 240 NWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQ Sbjct: 181 NWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQ 240 Query: 241 LVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQ 300 LVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQ Sbjct: 241 LVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQ 300 Query: 301 LALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTD 360 LALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTD Sbjct: 301 LALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTD 360 Query: 361 PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPW 420 PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPW Sbjct: 361 PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPW 420 Query: 421 GGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAA 480 GGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAA Sbjct: 421 GGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAA 480 Query: 481 GGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGS 540 GGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGS Sbjct: 481 GGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGS 540 Query: 541 PPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGP 600 PPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGP Sbjct: 541 PPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGP 600 Query: 601 SVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPF 660 SVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPF Sbjct: 601 SVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPF 660 Query: 661 LL 662 LL Sbjct: 661 LL 662 >gi|41350201 epsin 1 isoform c [Homo sapiens] Length = 550 Score = 1131 bits (2926), Expect = 0.0 Identities = 550/551 (99%), Positives = 550/551 (99%), Gaps = 1/551 (0%) Query: 112 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 171 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI Sbjct: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60 Query: 172 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 231 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG Sbjct: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120 Query: 232 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 291 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS Sbjct: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180 Query: 292 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT 351 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT Sbjct: 181 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT 240 Query: 352 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA 411 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA Sbjct: 241 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA 300 Query: 412 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK 471 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK Sbjct: 301 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK 360 Query: 472 PSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR 531 PSTNGTT AGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR Sbjct: 361 PSTNGTT-AGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR 419 Query: 532 GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL 591 GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL Sbjct: 420 GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL 479 Query: 592 PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG 651 PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG Sbjct: 480 PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG 539 Query: 652 PPAPNTNPFLL 662 PPAPNTNPFLL Sbjct: 540 PPAPNTNPFLL 550 >gi|194248095 epsin 1 isoform b [Homo sapiens] Length = 576 Score = 1124 bits (2906), Expect = 0.0 Identities = 551/576 (95%), Positives = 551/576 (95%), Gaps = 25/576 (4%) Query: 112 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 171 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI Sbjct: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60 Query: 172 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 231 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG Sbjct: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120 Query: 232 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 291 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS Sbjct: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180 Query: 292 SGEEELQLQLALAMSKEEADQ-------------------------EERIRRGDDLRLQM 326 SGEEELQLQLALAMSKEEADQ EERIRRGDDLRLQM Sbjct: 181 SGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQM 240 Query: 327 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 386 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP Sbjct: 241 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 300 Query: 387 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV 446 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV Sbjct: 301 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV 360 Query: 447 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS 506 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS Sbjct: 361 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS 420 Query: 507 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 566 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA Sbjct: 421 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 480 Query: 567 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 626 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP Sbjct: 481 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 540 Query: 627 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 662 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL Sbjct: 541 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 576 >gi|156671217 epsin 2 isoform a [Homo sapiens] Length = 584 Score = 488 bits (1257), Expect = e-138 Identities = 304/636 (47%), Positives = 366/636 (57%), Gaps = 137/636 (21%) Query: 112 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 171 M+TSS+RRQMKNIV+NYSEAEIKVREATSNDPWGPSSSLM+EIADLTYNVVAFSEIMSM+ Sbjct: 1 MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMV 60 Query: 172 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 231 WKRLNDHGKNWRHVYKA+TL++YLIKTGSERV+QQC+EN++A+QTLKDFQY+DRDGKDQG Sbjct: 61 WKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG 120 Query: 232 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSA-----AVGSGPP----- 281 +NVREK+KQLVALL+DE+RL+ ERA ALKTKE++AQ AT + GS P Sbjct: 121 INVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTS 180 Query: 282 -------------------------PEAEQAWPQSSGEEELQLQLALAMSKEEADQEERI 316 E EQA PQ+SGEEELQLQLALAMS+E A+QEER+ Sbjct: 181 HSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERL 240 Query: 317 RRGDDLRLQMAIEESKRET----GGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAV 372 RRGDDLRLQMA+EES+R+T KE SL + P++ P Sbjct: 241 RRGDDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSGP----------- 289 Query: 373 PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW-----RPAAPAGPSVDPWG-GTPAP 426 AA ++PWG +PWGGPA ++ DPW +PAA S+DPWG T A Sbjct: 290 --AAQKAEPWGPSASTNQTNPWGGPAAPASTSDPWPSFGTKPAA----SIDPWGVPTGAT 343 Query: 427 AAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFD-- 484 DPW +S +G ASD W A +T + +G F+ Sbjct: 344 VQSVPKNSDPWAASQQPASSAGKRASDAW-------------GAVSTTKPVSVSGSFELF 390 Query: 485 -----TEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVG 539 T D+FS+FD LRT+ T+ S +P+++ G Sbjct: 391 SNLNGTIKDDFSEFDNLRTSKKTAES--------VTSLPSQNNGTTSPDPFESQPLTVAS 442 Query: 540 SPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATG 599 S P +A RKTPESFLGPNAALV+LDSLV+RP P A++ NPFL G PAT Sbjct: 443 SKPSSA--------RKTPESFLGPNAALVNLDSLVTRPAPP---AQSLNPFLAPGAPATS 491 Query: 600 PSVTNPFQPAPPATLTLNQLRLSPV--------------------------PPVPGAPPT 633 V NPFQ P LTLNQLR SPV P GA + Sbjct: 492 APV-NPFQVNQPQPLTLNQLRGSPVLGTSTSFGPGPGVESMAVASMTSAAPQPALGATGS 550 Query: 634 YISPLG-------GGPGLPPMMPPGPPAPNTNPFLL 662 ++PLG G G+PP TNPFLL Sbjct: 551 SLTPLGPAMMNMVGSVGIPP--SAAQATGTTNPFLL 584 >gi|157388929 epsin 3 [Homo sapiens] Length = 632 Score = 414 bits (1064), Expect = e-115 Identities = 287/672 (42%), Positives = 354/672 (52%), Gaps = 162/672 (24%) Query: 112 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 171 M+TS+LRRQ+KNIVHNYSEAEIKVREATSNDPWGP SSLMSEIADLT+N VAF+E+M M+ Sbjct: 1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGML 60 Query: 172 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 231 W+RLND GKNWRHVYKA+TL++YL+KTGSERV+ QC+EN+Y +QTLKDFQY+DRDGKDQG Sbjct: 61 WRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQG 120 Query: 232 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLA-----------------------QT 268 VNVREK KQ++ALL+DE+RLR+ER HALKTKE++A Sbjct: 121 VNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSR 180 Query: 269 ATASSAAVGSGPP---PEAEQAWPQSSGEEELQLQLALAMSKEEADQ--EERIRRGDDLR 323 + SS S P + EQA PQ+SGEEELQLQLALAMS+EEA++ R +DL+ Sbjct: 181 GSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQ 240 Query: 324 LQMAI----------------------------------EESKRETGGKEE------SSL 343 LQ+A+ E +RE +EE SS+ Sbjct: 241 LQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSI 300 Query: 344 MDLADVFTAPAPAPTT----DPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 399 +DLAD+F P+T DPW P P + WG P+ADPW P P Sbjct: 301 LDLADIFVPALAPPSTHCSADPWDIP----GFRPNTEASGSSWG-----PSADPW-SPIP 350 Query: 400 TP---ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWT 456 + + PW P S +PWG TP AG PT DPW ++ P P T Sbjct: 351 SGTVLSRSQPW-DLTPMLSSSEPWGRTPVLPAGP-PTTDPWA-------LNSPHHKLPST 401 Query: 457 PAPAFSDPWGGSPAKPST-NGTTAAGGFDTEPDEFSDFDRLRTALPT-SGSSAGELELLA 514 A DPWG S T G + F P+ + L ALP+ SS EL+L Sbjct: 402 GA----DPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFG 457 Query: 515 GEVPA------RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNA-AL 567 P+ + P A D+ G L EA+ P A +TPESFLGP+A +L Sbjct: 458 DPSPSSKQNGTKEPDALDL----GILGEALTQPSKEARAC------RTPESFLGPSASSL 507 Query: 568 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL-SPVPP 626 V+LDSLV P AK NPFL G + PS TNPF P TLNQ+R SP Sbjct: 508 VNLDSLVK----APQVAKTRNPFLTG---LSAPSPTNPFGAGEPGRPTLNQMRTGSPALG 560 Query: 627 VPGAP--------------PTYISPLGGGPGLP---------------PMMP-------- 649 + G P P +S + G LP P++P Sbjct: 561 LAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPR 620 Query: 650 PGPPAPNTNPFL 661 P PP TNPFL Sbjct: 621 PPPPQTGTNPFL 632 >gi|156671215 epsin 2 isoform b [Homo sapiens] Length = 641 Score = 410 bits (1053), Expect = e-114 Identities = 281/681 (41%), Positives = 350/681 (51%), Gaps = 170/681 (24%) Query: 112 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 171 M+TSS+RRQMKNIV+NYSEAEIKVREATSNDPWGPSSSLM+EIADLTYNVVAFSEIMSM+ Sbjct: 1 MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMV 60 Query: 172 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 231 WKRLNDHGKNWRHVYKA+TL++YLIKTGSERV+QQC+EN++A+QTLKDFQY+DRDGKDQG Sbjct: 61 WKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG 120 Query: 232 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSA-----AVGSGPP----P 282 +NVREK+KQLVALL+DE+RL+ ERA ALKTKE++AQ AT + GS P Sbjct: 121 INVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTS 180 Query: 283 EAEQAWPQSSG-------------------------EEELQ---------LQLALAMSKE 308 +EQ + ++ G EELQ L LA S+ Sbjct: 181 HSEQEYGKAGGSPASYHGSPEASLCPQHRTGAPLGQSEELQPLSQRHPFLPHLGLA-SRP 239 Query: 309 EADQE------ERIRRGDDLRLQMAIEESKRETGGKEESSL------------------- 343 D +R R R+ +E+++ +T G+EE L Sbjct: 240 NGDWSQPCLTCDRAARATSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERLRR 299 Query: 344 -------MDLADVFTAPAPAPTTDPWGGPAPMAA------AVPTAAPT---SDPWGGPPV 387 M L + P G A+P++ P ++PWG Sbjct: 300 GDDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSGPAAQKAEPWGPSAS 359 Query: 388 PPAADPWGGPAPTPASGDPW-----RPAAPAGPSVDPWG-GTPAPAAGEGPTPDPWGSSD 441 +PWGGPA ++ DPW +PAA S+DPWG T A DPW +S Sbjct: 360 TNQTNPWGGPAAPASTSDPWPSFGTKPAA----SIDPWGVPTGATVQSVPKNSDPWAASQ 415 Query: 442 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFD-------TEPDEFSDFD 494 +G ASD W A +T + +G F+ T D+FS+FD Sbjct: 416 QPASSAGKRASDAW-------------GAVSTTKPVSVSGSFELFSNLNGTIKDDFSEFD 462 Query: 495 RLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTR 554 LRT+ T+ S +P+++ G S P +A R Sbjct: 463 NLRTSKKTAES--------VTSLPSQNNGTTSPDPFESQPLTVASSKPSSA--------R 506 Query: 555 KTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL 614 KTPESFLGPNAALV+LDSLV+RP P A++ NPFL G PAT V NPFQ P L Sbjct: 507 KTPESFLGPNAALVNLDSLVTRPAPP---AQSLNPFLAPGAPATSAPV-NPFQVNQPQPL 562 Query: 615 TLNQLRLSPV--------------------------PPVPGAPPTYISPLG-------GG 641 TLNQLR SPV P GA + ++PLG G Sbjct: 563 TLNQLRGSPVLGTSTSFGPGPGVESMAVASMTSAAPQPALGATGSSLTPLGPAMMNMVGS 622 Query: 642 PGLPPMMPPGPPAPNTNPFLL 662 G+PP TNPFLL Sbjct: 623 VGIPP--SAAQATGTTNPFLL 641 >gi|31377575 ENTH domain containing 1 [Homo sapiens] Length = 607 Score = 211 bits (538), Expect = 1e-54 Identities = 98/163 (60%), Positives = 129/163 (79%) Query: 116 SLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRL 175 + RRQ+KN V NYS+AEIKVREATSNDPWGPSSSLM +I+DLT+N ++ SEIM+M+W RL Sbjct: 2 AFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRL 61 Query: 176 NDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVR 235 NDHGKNWRHVYK++TLM+YLIK GS++V Q C+E +QTLKDFQ++D GKDQG +R Sbjct: 62 NDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIR 121 Query: 236 EKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGS 278 EK+KQ++ LL DE L +ER A +T+++ + + S +GS Sbjct: 122 EKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGS 164 >gi|156671219 epsin 2 isoform c [Homo sapiens] Length = 356 Score = 189 bits (480), Expect = 7e-48 Identities = 147/408 (36%), Positives = 186/408 (45%), Gaps = 102/408 (25%) Query: 305 MSKEEADQEERIRRGDDLRLQMAIEESKRET----GGKEESSLMDLADVFTAPAPAPTTD 360 MS+E A+QEER+RRGDDLRLQMA+EES+R+T KE SL + P++ Sbjct: 1 MSREVAEQEERLRRGDDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSG 60 Query: 361 PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW-----RPAAPAGP 415 P AA ++PWG +PWGGPA ++ DPW +PAA Sbjct: 61 P-------------AAQKAEPWGPSASTNQTNPWGGPAAPASTSDPWPSFGTKPAA---- 103 Query: 416 SVDPWG-GTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPST 474 S+DPWG T A DPW +S +G ASD W A +T Sbjct: 104 SIDPWGVPTGATVQSVPKNSDPWAASQQPASSAGKRASDAW-------------GAVSTT 150 Query: 475 NGTTAAGGFD-------TEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDM 527 + +G F+ T D+FS+FD LRT+ T+ S +P+++ G Sbjct: 151 KPVSVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAES--------VTSLPSQNNGTTSP 202 Query: 528 SGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKAS 587 S P +A RKTPESFLGPNAALV+LDSLV+RP P A++ Sbjct: 203 DPFESQPLTVASSKPSSA--------RKTPESFLGPNAALVNLDSLVTRPAPP---AQSL 251 Query: 588 NPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPV----------------------- 624 NPFL G PAT V NPFQ P LTLNQLR SPV Sbjct: 252 NPFLAPGAPATSAPV-NPFQVNQPQPLTLNQLRGSPVLGTSTSFGPGPGVESMAVASMTS 310 Query: 625 ---PPVPGAPPTYISPLG-------GGPGLPPMMPPGPPAPNTNPFLL 662 P GA + ++PLG G G+PP TNPFLL Sbjct: 311 AAPQPALGATGSSLTPLGPAMMNMVGSVGIPP--SAAQATGTTNPFLL 356 >gi|7661968 epsin 4 [Homo sapiens] Length = 625 Score = 169 bits (429), Expect = 6e-42 Identities = 86/175 (49%), Positives = 118/175 (67%), Gaps = 4/175 (2%) Query: 123 NIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKR-LNDHGKN 181 N+V NYSE E KVREAT++DPWGPS LM EIA T+ F E+M+M+W R L D+ KN Sbjct: 16 NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75 Query: 182 WRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQL 241 WR VYK++ L+ YLI+ GSERV +E++Y +++L+++ +VD GKDQG+N+R+K K+L Sbjct: 76 WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135 Query: 242 VALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEE 296 V +D+DRLREER A K K+K SS +VG E P+S +EE Sbjct: 136 VEFAQDDDRLREERKKAKKNKDKY---VGVSSDSVGGFRYSERYDPEPKSKWDEE 187 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 92.0 bits (227), Expect = 2e-18 Identities = 107/365 (29%), Positives = 128/365 (35%), Gaps = 70/365 (19%) Query: 351 TAPA---PAPTTDPWGGPAPMAAAVPTAAPTSDPWGGP---------PVPPAA---DPWG 395 T PA P+P P P P A+ P AA P G P P PAA P G Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069 Query: 396 GPAPTPASGDPWRPAAP-----AGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS 450 GPA G P PAA GP+ G P P A P+P GG+ + P Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK------GGL-ATPPH 1122 Query: 451 ASDPWTPAPAFSDPWGG--------SPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT 502 P TPA P GG +P P+ + GG T P + + T Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182 Query: 503 SGSSAGELELLAGEVPARSP----GAFDMSGVRGSLAEAVGSPPPA----ATPTP----T 550 G A A PA +P G +G+ +PP ATP+P T Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242 Query: 551 PPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAK----------ASNPFL-----PGGG 595 P P GP A + P TPP K A NP + P GG Sbjct: 1243 TPAATPPSPKGGP--ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300 Query: 596 PATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAP-PTYISPLG--GGPGLPPMMPPGP 652 PAT P P PPA + PP GAP P ++P G P LP P Sbjct: 1301 PATSPP---KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357 Query: 653 PAPNT 657 P T Sbjct: 1358 GGPTT 1362 Score = 92.0 bits (227), Expect = 2e-18 Identities = 112/366 (30%), Positives = 132/366 (36%), Gaps = 75/366 (20%) Query: 353 PAPAPTT------DPWGGPAPMA---AAVPTAAPTSDPWGGP--------PVPPAADPWG 395 P APTT P GGPA + A P AA P GGP P+PPAA P Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP-- 1110 Query: 396 GPAPTPASGDPWRPAAPAGPSVDP----WGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSA 451 P+P P AP P+ P G P G TP S G + P Sbjct: 1111 -PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169 Query: 452 SDPWTPAPAFSDPWG--------GSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTS 503 P TPA P G G+P P+ + GG T + + T Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229 Query: 504 GSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTP---TPPTRK----T 556 G A A PA +P +G A +PPP PTP TPP+ K T Sbjct: 1230 GGLATPSPKGAPTTPAATP-----PSPKGGPA----TPPPKGAPTPPAATPPSLKGGLAT 1280 Query: 557 PESFLGPNAALVDLDSLVSRPGPTPP-GA---KASNPFLPGGGPATGPSVTNPFQPA--- 609 P PN A+V S P +PP GA A+ P P G P T P P PA Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340 Query: 610 --PPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP--------GLPPMMPPGP------P 653 P T TL + P G P T S G P G P M PP P P Sbjct: 1341 PSPKGTPTLP----ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396 Query: 654 APNTNP 659 +P +P Sbjct: 1397 SPKGDP 1402 Score = 90.1 bits (222), Expect = 6e-18 Identities = 105/371 (28%), Positives = 135/371 (36%), Gaps = 85/371 (22%) Query: 351 TAPAPAPTTDPWGG---PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPAS---- 403 T PA P + P GG P P A AA P GG PP PA TP S Sbjct: 1127 TTPAATPPS-PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185 Query: 404 ----GDPWRPAAPAGPSVDPWGGTPAPAAGEGPT------PDPWGS----SDGGVPVSGP 449 P PA P GG P+ PT P P G S G P + P Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT-P 1244 Query: 450 SASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGE 509 +A+ P + P G+P P+ + GG T P + + + T G A Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304 Query: 510 LELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTP---TPPTRK--------TPE 558 A PA +P + +GS G+PPP PTP TPP+ K TP Sbjct: 1305 PPKGAPTPPAATPPS-----PKGS----PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355 Query: 559 SFLGPNAALVDLDSLVSRPGPTPPGAKASN---PFLPGGGPATGPSVTNPF-QPAPPATL 614 S GP S+ GPTPP A S+ P + P GP++ +P P PA + Sbjct: 1356 SKGGPTTPS-------SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408 Query: 615 TLNQLRLSPVPPV---------------PGAPPTYI-------SPLGG--------GPGL 644 L+ + +P PV P P + +P GG P L Sbjct: 1409 PLSPKK-APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467 Query: 645 PPMMPPGPPAP 655 P + PP P P Sbjct: 1468 PAVTPPSPKEP 1478 Score = 77.8 bits (190), Expect = 3e-14 Identities = 101/334 (30%), Positives = 117/334 (35%), Gaps = 51/334 (15%) Query: 352 APAPAPTTDPWGGPAPMAAAVPT--AAPTSDPWGGPPVPPAA---DPWGGPA-PTPASGD 405 AP AP A A P P S G P PPAA P GGPA P+P Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP---- 959 Query: 406 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDP-WTPAPAFSDP 464 W P PA P GG P+ PTP ++ P GP+ P P P P Sbjct: 960 KWAPTPPAATPPSPKGGPATPSPKGAPTPP---AATPPSPKGGPATPSPKGAPTPPAVTP 1016 Query: 465 WGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 524 PS G+ AA F P S P +A L A PA + Sbjct: 1017 -------PSPKGSPAATPF---PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT--- 1063 Query: 525 FDMSGVRGSLA--EAVGSP-PPAATPTPTP---PTRKTPESFLGPNAAL--VDLDSLVSR 576 + +G A G+P PPAATP P+P P +P+ P AA L + Sbjct: 1064 --LPSPKGGPATPSLKGAPTPPAATP-PSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120 Query: 577 PGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSP---VPPVPGAPPT 633 P P A+ P P GG AT P P PA L P P P A P Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180 Query: 634 YISPLG--------GGPGLPPMMPPGPPAPNTNP 659 SP G G P P PP P P Sbjct: 1181 --SPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212 Score = 77.8 bits (190), Expect = 3e-14 Identities = 93/331 (28%), Positives = 117/331 (35%), Gaps = 61/331 (18%) Query: 351 TAPAPAPTTDPWGG---PAPMAAAVPTAAPTSDPWGGP--------PVPPAADP---WGG 396 T PA P + P GG P+P A AA P GGP P PPAA P GG Sbjct: 1219 TTPAATPPS-PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277 Query: 397 PAPTPASGDP-----WRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSA 451 A P G P P+ GP+ P G P P A P+P G P + P Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK-------GSPGTPPPK 1330 Query: 452 SDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS-AGEL 510 P PA P G+P P+T ++ G PT+ SS G Sbjct: 1331 GAPTPPAVTPPSP-KGTPTLPATTPSSKGG-------------------PTTPSSKEGPT 1370 Query: 511 ELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDL 570 A P S RG + P + P P +K P + + A Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP-KKAPATPVTREGAATPS 1429 Query: 571 DSLVSRPGPTPPG-AKASNPFLPGGGPATG--------PSVTNPF---QPAPPATLTLNQ 618 ++ P TP KA P GGPAT P+VT P PAP T + Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489 Query: 619 LRLSPVPPVPGAPPTYISPLGGGPGLPPMMP 649 + +P P P PT + + P P P Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSPKEVPATP 1520 Score = 67.8 bits (164), Expect = 3e-11 Identities = 95/313 (30%), Positives = 106/313 (33%), Gaps = 56/313 (17%) Query: 353 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDP-WRPAA 411 P P+ P+ P A P AP P A P P PAS P P Sbjct: 886 PTPSVVNLPFPKEGP-ATPAPKQAPALSMTSSSPKKARATP--APKGIPASPSPKGAPTP 942 Query: 412 PAGPSVDPWGG--TPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSP 469 PA P GG TP+P P S GG P + P PA P GG P Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA-PTPPAATPPSPKGG-P 1000 Query: 470 AKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSG 529 A PS G T P P +A A PA +P Sbjct: 1001 ATPSPKGAPTPPAV-TPPS------------PKGSPAATPFPKGASTPPAATP-----PS 1042 Query: 530 VRGSLAEAVGSPPPAATP----TPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAK 585 +GS PAATP PT P P GP + + PTPP Sbjct: 1043 PKGS---------PAATPLPKGAPTTPAATLPSPKGGPATPSL-------KGAPTPP--- 1083 Query: 586 ASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYI----SPLGGG 641 A+ P P GGPAT PS P PPA + PP GAP T SP GG Sbjct: 1084 AATPPSPKGGPAT-PSPKG--APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140 Query: 642 PGLPPMMPPGPPA 654 PP P PA Sbjct: 1141 ATPPPKGAPTTPA 1153 Score = 52.8 bits (125), Expect = 1e-06 Identities = 104/379 (27%), Positives = 131/379 (34%), Gaps = 92/379 (24%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAA-DPWGGPAP-----TPASG 404 ++P AP T PAPM A A S P P P + DP A TPA+ Sbjct: 1488 SSPKKAPAT-----PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL 1542 Query: 405 DPWRPAAPAGPSVDPWGGTPA-PAAGEGPT----------PDPWGSSDGGVP-------- 445 P P +V TPA P E P P S+ G P Sbjct: 1543 APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602 Query: 446 --VSGPSASDPWTPAPAFSDPWGGS-PAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT 502 V+ PS + TP PA + P PA P+ GT + P D PT Sbjct: 1603 PAVTSPSPKEAPTP-PAVTPPSPEKGPATPAPKGTPTSP--PVTPSSLKDS-------PT 1652 Query: 503 SGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPES--- 559 S +S + VP S G G +L E + +P P +TP T PTRK P++ Sbjct: 1653 SPASV--TCKMGATVPQASKGLPAKKGPT-ALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709 Query: 560 ----------------FLGPNAALVDL----------------DSLVSRPGP-TPPGAKA 586 GP + + D+ S GP PP +KA Sbjct: 1710 SATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKA 1769 Query: 587 SNPFLPGGGPATGP---SVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPG 643 S P P S + P+PP +L L SPVP +P P P PG Sbjct: 1770 STPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP---SPVPTLP--PKQQFLP--SSPG 1822 Query: 644 LPPMMPPGPPAPNTNPFLL 662 L P P AP LL Sbjct: 1823 LVLESPSKPLAPADEDELL 1841 Score = 50.4 bits (119), Expect = 5e-06 Identities = 90/340 (26%), Positives = 113/340 (33%), Gaps = 46/340 (13%) Query: 339 EESSLMDLADVFTAPAPAPTT-DPWGGPAPMAAAV-PTAAPTSDPWGGPPVPPAADPWGG 396 +E +L L V TA P P AP+A V P S P P +PPA P G Sbjct: 691 KEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVP--SPSLPPAGTPPGT 748 Query: 397 PAPTPASGDPWRPAAPAGPSVDPW--GGTPAPAAGEGP------TPDPWG---SSDGGVP 445 S + P P G A A+ +G +P P G S P Sbjct: 749 KKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP 808 Query: 446 VSGPSASDPWTPAPAFSDPWGGSPAKPS---TNGTTAAGGFDTEPDEFSDFDRLRTALPT 502 + ++ P TP S P SP + S N + G D+ S PT Sbjct: 809 PTKKGSAGPDTPIGNLSSPV--SPVEASFLPENSLSFQGSKDSPATTHS---------PT 857 Query: 503 SGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRK-TPESFL 561 S G A +P A +G +P P+ P P TP Sbjct: 858 PPSPKG----------APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907 Query: 562 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL 621 P ++ +R P P G AS P G P T P+ T P PAT + Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPS--PKGAP-TPPAATPPSPKGGPATPSPKWAPT 964 Query: 622 SP--VPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNP 659 P PP P P SP G P P PP P P Sbjct: 965 PPAATPPSPKGGPATPSP-KGAPTPPAATPPSPKGGPATP 1003 Score = 40.8 bits (94), Expect = 0.004 Identities = 70/302 (23%), Positives = 106/302 (35%), Gaps = 22/302 (7%) Query: 370 AAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAG 429 AA PT PP+ ++ P PT + P AP PS P + Sbjct: 450 AAAPTTTFEVATCVSPPM--SSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSP 507 Query: 430 EGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGG------F 483 P P+ + V V P+ D T PA + G+P P+ G T Sbjct: 508 PLPDPEDLKNLPSSVLVKFPTQKDLQT-VPASLE---GAPFSPAQAGLTTKKDPTVLPLV 563 Query: 484 DTEPDEFSDFDRLRTA--LPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSP 541 P F ++ +P S + + L +P P + S + + + +V Sbjct: 564 QAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKT 623 Query: 542 PPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPS 601 A P P K+ S + P A L+S G P AK ++ + P + Sbjct: 624 DSYAGPDSAGPLLKS--SLITPTVAAFPLES-ADPAGVAPTTAKGTSTYTTTASPFLEGT 680 Query: 602 VTNPFQPAPPATLTLNQLRLSPVP----PVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 657 V+ + P TL L L P PV +P +PL L P +P P+P+ Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPL-ATLVLAPEIPKSVPSPSL 739 Query: 658 NP 659 P Sbjct: 740 PP 741 Score = 35.4 bits (80), Expect = 0.17 Identities = 78/330 (23%), Positives = 115/330 (34%), Gaps = 38/330 (11%) Query: 352 APAPAPTT---DPWGGPAPMAA---AVPTA----APTSDP-WGGPPVPPAADPWGGP--A 398 +P P+P+T P P P ++ A+P APT P GPP+ PAA P A Sbjct: 65 SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIA 124 Query: 399 P----TPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSA-SD 453 P TP+S P A A SV P P P S + +S P A S+ Sbjct: 125 PTLKGTPSSSAPLALVALAPHSVQKSSAFP-PNLLTSPPSVAVAESGSVITLSAPIAPSE 183 Query: 454 PWT-----PAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT-----S 503 P T P+ +P G+P+ P T S L PT + Sbjct: 184 PKTNLNKVPSEVVPNP-KGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIA 242 Query: 504 GSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGP 563 + + + + ++PG+ + G V P + T + P + + GP Sbjct: 243 SPQVKDTTISSVLISPQNPGSLSLKG-------PVSPPAALSLSTQSLPVVTSSQKTAGP 295 Query: 564 NAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP-ATGPSVTNPFQPAPPATLTLNQLRLS 622 N SL S P + S L GP A +T + S Sbjct: 296 NTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRS 355 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPMMPPGP 652 +PP+P + + P + P + GP Sbjct: 356 VIPPLPSRNEVVPATVAAFPVVAPSVDKGP 385 Score = 33.9 bits (76), Expect = 0.49 Identities = 32/133 (24%), Positives = 50/133 (37%), Gaps = 13/133 (9%) Query: 533 SLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLP 592 S+ A+G P P P +P ++ P S + ++ S P P +S LP Sbjct: 33 SVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALP 92 Query: 593 GG----GPATGPSVTNPFQPAPPATLTLNQLRLSPV---PPVPGAPPTYIS----PLGGG 641 G P P++ P P PA L L ++P P AP ++ + Sbjct: 93 LGTAPEAPTFLPNLIGP--PISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKS 150 Query: 642 PGLPPMMPPGPPA 654 PP + PP+ Sbjct: 151 SAFPPNLLTSPPS 163 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 79.0 bits (193), Expect = 1e-14 Identities = 91/327 (27%), Positives = 121/327 (37%), Gaps = 43/327 (13%) Query: 353 PAPAPTTDPWG-GPA-PMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDP--WR 408 PA P+ DP+G PA P+ PTA PT P+ P PA P G + P +G P + Sbjct: 2168 PAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFH 2227 Query: 409 PAAPAGP-----SVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSD 463 P P + DP+ P+ P+ G V G AS+P P F + Sbjct: 2228 TTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG-------VGGGKASEPLLSPPPFGE 2280 Query: 464 PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEV--PARS 521 K G ++ P D P+SG+ G LEL +V + Sbjct: 2281 SRKALEVKKEELGASSP---SYGPPNLGFVDS-----PSSGTHLGGLELKTPDVFKAPLT 2332 Query: 522 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRK---TPESFLGPNAALVDLDSLVSRPG 578 P A + L PPPA P+PP+ P S+ P A L RP Sbjct: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ----PPLTPRPQ 2388 Query: 579 PTPPGAKASNP--FLPGGG----PATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPP 632 P PP + + P LP PA+ S ++ P P L+ SPV P +P Sbjct: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPD 2448 Query: 633 TY----ISPLGGGPGLPPMMPPGPPAP 655 Y P P P PP P P Sbjct: 2449 PYSRPPSRPQSRDPFAPLHKPPRPQPP 2475 Score = 59.7 bits (143), Expect = 8e-09 Identities = 84/322 (26%), Positives = 114/322 (35%), Gaps = 69/322 (21%) Query: 354 APAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPA 413 +P P P P P ++P S P PP P P+PA P P A Sbjct: 495 SPPPEESPLSPP-------PESSPFSPLEESPLSPPEESP-----PSPALETPLSPPPEA 542 Query: 414 GPSVDPWGGTP-APAAGEGPTPDPWGSS-----DGGVPVSGPSASDPWTPAPAFS---DP 464 P P+ +P +P E PT P +S P+S P P +P P S P Sbjct: 543 SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602 Query: 465 WGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 524 + SP P + + P E S R + P S P SP + Sbjct: 603 FEESPLSPPPEESPL-----SPPPEAS-----RLSPPPEDSP-------MSPPPEESPMS 645 Query: 525 FDMSGVRGSLAEAVG--SPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 582 R S V SPPP +P +PP ++P S P P Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPL-SPPPEESPTS-------------------PPPE 685 Query: 583 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 642 ++ S P P P + P +P P P +L L SP+ P+P P + P GP Sbjct: 686 ASRLSPP--PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP--QLCPRSEGP 741 Query: 643 GLPPM-----MPPGPPAPNTNP 659 L P + P P P+ +P Sbjct: 742 HLSPRPEEPHLSPRPEEPHLSP 763 Score = 50.8 bits (120), Expect = 4e-06 Identities = 78/300 (26%), Positives = 103/300 (34%), Gaps = 42/300 (14%) Query: 373 PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW------RPAAPAGPSVDPWGGTPAP 426 P PT +P V P GG + +P +P AG ++P AP Sbjct: 377 PGDTPTDEP-DALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQ--LEAP 433 Query: 427 AAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPA---FSDPWGGSPAKPSTNGTTAAGGF 483 E P P S P+S P P +P P S P PA P + Sbjct: 434 LNEEMPLLPPPEES----PLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPL 489 Query: 484 DTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPP 543 + P + + P S LE P SP + E SPPP Sbjct: 490 EESPLSPPP-EESPLSPPPESSPFSPLEESPLSPPEESPPS--------PALETPLSPPP 540 Query: 544 AATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVT 603 A+P +PP ++P S P L P PP A +P P P + P Sbjct: 541 EASPL-SPPFEESPLS--PPPEEL---------PTSPPPEASRLSP-PPEESPMSPPPEE 587 Query: 604 NPFQPAPPATLTLNQLRLSPVPPVPG----APPTYISPLGGGPGLPPMMPPGPPAPNTNP 659 +P P P A+ SP+ P P +PP S L P PM PP +P + P Sbjct: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647 Score = 50.4 bits (119), Expect = 5e-06 Identities = 57/155 (36%), Positives = 64/155 (41%), Gaps = 51/155 (32%) Query: 537 AVGSPPPAATPT-----PTPPT--RKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNP 589 A+GSPPPAA PT PT P + + FL P A V PGP PG Sbjct: 2112 ALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSV--------PGPDSPGELFLK- 2162 Query: 590 FLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPT---YISPLGGGPGLPP 646 LP PA PS +PF AP L P P APPT Y SP G P PP Sbjct: 2163 -LPPQVPAQVPS-QDPFGLAPAYPLE---------PRFPTAPPTYPPYPSPT-GAPAQPP 2210 Query: 647 MM-----------------PPGPP--APNT-NPFL 661 M+ PPG P P+T +PFL Sbjct: 2211 MLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFL 2245 Score = 44.3 bits (103), Expect = 4e-04 Identities = 70/247 (28%), Positives = 89/247 (36%), Gaps = 30/247 (12%) Query: 426 PAAGEGPT--PDPWGSSDGGVPVSGPSAS-DPWTPAPAFSD--PWG--GSPAKPSTNGTT 478 P G+ PT PD + G P G S P P P + P G G +P Sbjct: 375 PEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPL 434 Query: 479 AAGGFDTEPDEFSDFDRLRTALPTSGS-SAGELELLAGEVPARS-PGAFDMSGVRGSLAE 536 P E S PTS A L E+PA P A +S L E Sbjct: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSR---PLEE 491 Query: 537 AVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPG--G 594 + SPPP +P +PP +P S L +S +S P +PP P P Sbjct: 492 SPLSPPPEESPL-SPPPESSPFSPLE--------ESPLSPPEESPPSPALETPLSPPPEA 542 Query: 595 GPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPG-APPTYISPLGGGPGLPPMMPPGPP 653 P + P +P P P +L SP P +PP SP+ P PM PP Sbjct: 543 SPLSPPFEESPLSPPP------EELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596 Query: 654 APNTNPF 660 + PF Sbjct: 597 SRLFPPF 603 Score = 44.3 bits (103), Expect = 4e-04 Identities = 75/277 (27%), Positives = 100/277 (36%), Gaps = 51/277 (18%) Query: 363 GGPAPMAAAVPTAAPTSDPWGGPPVPPAA--DPWG-----GPAPT----------PASGD 405 G P+PM P A +P PPVP P G GP PT A+G+ Sbjct: 2529 GTPSPMRFTFPQAV--GEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGN 2586 Query: 406 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDP---WTPAPAFS 462 +P GPS G + + P+ P + DG +P AS +P Sbjct: 2587 FHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRE 2646 Query: 463 DPWGGSPAK------PSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGE 516 DP G + P T +G TE ++ RLR ELL + Sbjct: 2647 DPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLR-------------ELLIRQ 2693 Query: 517 VPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSR 576 R+ + + A AVG PP + P+ P + P A D SLV Sbjct: 2694 QIQRNTLRQEKE-TAAAAAGAVG-PPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGL 2751 Query: 577 PGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT 613 P +K S P L GP + PS +P PPAT Sbjct: 2752 -----PPSKLSGPIL---GPGSFPSDDRLSRPPPPAT 2780 Score = 41.2 bits (95), Expect = 0.003 Identities = 88/336 (26%), Positives = 116/336 (34%), Gaps = 46/336 (13%) Query: 353 PAPAPTTDPW-GGPA------PMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 405 P P+ P G PA P + +P P S P G P + P P P P P Sbjct: 885 PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS-PSGEPSLSPQLMP---PDPLPPPLS 940 Query: 406 PWRPAAPAGPSVDPWGGTPAP--AAGEGPTPDPWGSSDGGVPVSGP---SASDPWTPAPA 460 P AA A P++ P G P A G+ P + P+S P + +DP P Sbjct: 941 PIITAA-APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM 999 Query: 461 FSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 520 P GSP P A EP L+ +L S + A + Sbjct: 1000 ILPPSPGSPVGP-------ASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP 1052 Query: 521 SP--------GAFDMSGVRGSLAEAVGSPP-PAATPTPTPPTRKTPESFLG-----PNAA 566 SP G D + + E V P PA P+ T P +P L P A Sbjct: 1053 SPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL-PSPMGDLSCPAPSPAPA 1111 Query: 567 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 626 L D L P G A PG P G + + + + L+ L+PV P Sbjct: 1112 LDDFSGLGEDTAPLD-GIDA-----PGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTP 1165 Query: 627 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 662 + P + G P P P AP T P L+ Sbjct: 1166 MEVYPECKQTAGQGSPCEEQEEPRAPVAP-TPPTLI 1200 Score = 38.9 bits (89), Expect = 0.015 Identities = 83/346 (23%), Positives = 113/346 (32%), Gaps = 49/346 (14%) Query: 354 APAPTTDPWGGP--APMAAAVPTAAPTSDPWGGPPV-PPAADPWGGPAPTPASGDPWRPA 410 +P P P P A + P +P S P P+ PP P P + P Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668 Query: 411 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDP---WTPAPAFSDPWGG 467 +P P + +P P A +P P S P P++ P P P Sbjct: 669 SPLSPPPEESPTSPPPEASR-LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP 727 Query: 468 SPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELEL----------LAGEV 517 P +P + P+E R P A E L E Sbjct: 728 LPEEPQLCPRSEGPHLSPRPEE--PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE 785 Query: 518 PARSPGAFD--MSGVRGSLAEAVGSPPPAATPTPTPP-----------TRKTPESFLGPN 564 P SP A +S L + + P +P P P + ++ E L P Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPR 845 Query: 565 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPV 624 L + +P +P K P PG PA P PP +L+ L P Sbjct: 846 PEESHLSPELEKPPLSPRPEKP--PEEPGQCPAPEELPLFP----PPGEPSLSPLLGEPA 899 Query: 625 PPVPGAPPTYISPL--------GGGPGLPP-MMPPGPPAPNTNPFL 661 PG PP +SPL G P L P +MPP P P +P + Sbjct: 900 LSEPGEPP--LSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPII 943 Score = 37.7 bits (86), Expect = 0.034 Identities = 67/277 (24%), Positives = 88/277 (31%), Gaps = 63/277 (22%) Query: 388 PPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS 447 P + +P P P + P P P + P G+ P P+ P Sbjct: 835 PQSEEPCLSPRPEESHLSPELEKPPLSPRPEK----PPEEPGQCPAPEELPL----FPPP 886 Query: 448 GPSASDPWTPAPAFSDPWGGSPAKP-------STNGTTAAGGFDTEPDEFSD--FDRLRT 498 G + P PA S+P G P P S +G + PD + Sbjct: 887 GEPSLSPLLGEPALSEP-GEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITA 945 Query: 499 ALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPE 558 A P + S GELE G P S + + E SPPP A T Sbjct: 946 AAPPALSPLGELEYPFGAKGDSDPE----SPLAAPILETPISPPPEANCTD--------- 992 Query: 559 SFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQ 618 P P PP +P G GP+ +P PP L Q Sbjct: 993 ------------------PEPVPPMILPPSP-----GSPVGPASPILMEPLPPQCSPLLQ 1029 Query: 619 LRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 655 L P +PP+ SP P L P+ P P +P Sbjct: 1030 HSLVP----QNSPPSQCSP----PAL-PLSVPSPLSP 1057 Score = 36.6 bits (83), Expect = 0.076 Identities = 46/189 (24%), Positives = 70/189 (37%), Gaps = 37/189 (19%) Query: 279 GPPPEAEQAWP-----QSSGEEELQLQLALA-------MSKEEADQEERIRRGDDLRLQM 326 GP ++ Q P + G+ QLQ LA +S ++ Q + + L+ Sbjct: 4176 GPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQ 4235 Query: 327 AIEESKR-ETGGKEESSLMDLADV------FTAPAPAPTTDPWGGPAPMAAA---VPTAA 376 A+ ++ + G + S L L F P P + GP P P A Sbjct: 4236 AVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGA 4295 Query: 377 PTSDPWGGP--PVPPAADPW-----------GGPAPTPASGDPWRPAAPA--GPSVDPWG 421 ++ P GP P PP + P PT A P P P GP+++P Sbjct: 4296 LSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPP 4355 Query: 422 GTPAPAAGE 430 G +PAA + Sbjct: 4356 GRVSPAAAQ 4364 Score = 36.6 bits (83), Expect = 0.076 Identities = 42/134 (31%), Positives = 56/134 (41%), Gaps = 20/134 (14%) Query: 535 AEAVGSPPPAATP-TPTPPTRKT----PE--SFLGPNAALVDLDSLVSRPG-----PTPP 582 ++AV PP P T T P + P+ F GP + RP P PP Sbjct: 4234 SQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPP 4293 Query: 583 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYI-SPLGGG 641 GA ++ P L P PS +P +P P+ L S +P PPT+ +P G Sbjct: 4294 GALSTGPVLGPVHPTPPPS--SPQEPKRPSQLPSPS---SQLPTEAQLPPTHPGTPKPQG 4348 Query: 642 PGLPPMMPPGPPAP 655 P L P PPG +P Sbjct: 4349 PTLEP--PPGRVSP 4360 Score = 33.9 bits (76), Expect = 0.49 Identities = 51/210 (24%), Positives = 71/210 (33%), Gaps = 17/210 (8%) Query: 346 LADVFTAPAPAPTTD------PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 399 L+ + TA AP + P+G P AAP + P PP P P Sbjct: 939 LSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILET---PISPPPEANCTDPEP 995 Query: 400 TPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP 459 P P P +P GP+ P P P P P S PS P PA Sbjct: 996 VPPMILPPSPGSPVGPA-SPILMEPLP-----PQCSPLLQHSLVPQNSPPSQCSP--PAL 1047 Query: 460 AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPA 519 S P SP + A + E ++ S+ + + + L+ P+ Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPS 1107 Query: 520 RSPGAFDMSGVRGSLAEAVGSPPPAATPTP 549 +P D SG+ A G P + P P Sbjct: 1108 PAPALDDFSGLGEDTAPLDGIDAPGSQPEP 1137 Score = 31.6 bits (70), Expect = 2.4 Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 13/90 (14%) Query: 568 VDLDSLVSRPGPTP-PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 626 +D+ SL+ + P P P + S + S P +P+PP SP+ P Sbjct: 4873 LDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPP---------SPLAP 4923 Query: 627 VPGAPPTYISPLGGGPGLPPMMPPGP-PAP 655 P +PPT PL P P PP P P P Sbjct: 4924 SPASPPT--EPLVELPTEPLAEPPVPSPLP 4951 Score = 30.0 bits (66), Expect = 7.1 Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 2/68 (2%) Query: 348 DVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW 407 DV AP P +P P+P+A + P + PT P P A P P P +S + Sbjct: 4902 DVRQLSAPPPE-EPSPPPSPLAPS-PASPPTEPLVELPTEPLAEPPVPSPLPLASSPESA 4959 Query: 408 RPAAPAGP 415 RP A P Sbjct: 4960 RPKPRARP 4967 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 74.3 bits (181), Expect = 3e-13 Identities = 104/345 (30%), Positives = 120/345 (34%), Gaps = 63/345 (18%) Query: 363 GGPAPMAAAVPTAAPTSDPWGGPPVPPA--ADPWGGPAPTPASGDPWRPAAPAGPS---- 416 G PA A A P A P P PPA A P GG P P RP PAGP+ Sbjct: 65 GSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAA 124 Query: 417 ---VDPWGG----TPAPAA---GEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWG 466 P G P PAA GP P P G + P + + + P P P G Sbjct: 125 KLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGP-GPGPGPGPGPG 183 Query: 467 GSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP-TSGSSAGELELLAGEVPARSPGAF 525 P KP+ G T + + A P S + G LL PA +PG Sbjct: 184 PGPGKPA-----GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPA-APGTV 237 Query: 526 DMS----GVRGSLAEAVGSPP-------PAATPTPTPPT-------------RKTPESFL 561 + G A A SPP PAA P P PP T + Sbjct: 238 IQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAV 297 Query: 562 GPNAALVDLDSLVSRPGPTP-PGAKASNPFLPGGG-----PATGPSVTNP---FQPAPPA 612 P AA + S + P P P G A PG G PA G +P Q APPA Sbjct: 298 PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPA 357 Query: 613 TLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 657 T L+ P A I P G LP PPAP T Sbjct: 358 AQT-----LAASGPASTAASMVIGPTMQG-ALPSPAAVPPPAPGT 396 Score = 58.9 bits (141), Expect = 1e-08 Identities = 86/327 (26%), Positives = 111/327 (33%), Gaps = 58/327 (17%) Query: 353 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGP-PVPPAADPWGGPAPTPASG-----DP 406 PAPA P GPA +AA A P P GP P P P G A +G + Sbjct: 152 PAPAGPAKP-AGPAALAAR---AGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207 Query: 407 WRPAAPA------GPS----------------VDPWGGTPAPAAGEGPTPDPWGSSDGGV 444 AAPA GP+ P+ G AP A P+P Sbjct: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPA-----APA 262 Query: 445 PVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSG 504 P + +A P PAPA G PA P T P + A P Sbjct: 263 PAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA------VPPPAAAQNGGSAGAAPAPA 316 Query: 505 SSAGELELLAGEVPARSPGAFDMSGVRGSLAEAV--GSPPPAATPTPTPPTRKTPESFLG 562 +AG ++G+ + A GV+ + V +PP A T + P +G Sbjct: 317 PAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG 376 Query: 563 PNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT-----LTLN 617 P + + P PP A + LP G +VT P AT TL Sbjct: 377 PT-----MQGALPSPAAVPPPAPGTPTGLPKGAAG---AVTQSLSRTPTATTSGIRATLT 428 Query: 618 QLRLSPVPPVPGAPPTYISPLGGGPGL 644 L+P P P PT I PG+ Sbjct: 429 PTVLAPRLPQPPQNPTNIQNFQLPPGM 455 Score = 57.8 bits (138), Expect = 3e-08 Identities = 93/344 (27%), Positives = 121/344 (35%), Gaps = 61/344 (17%) Query: 352 APAPAPTTDPWGG----PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW 407 AP T P+ G PAP A + P A + P PP PP PAP + P Sbjct: 233 APGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP-------PAPATLARPPG 285 Query: 408 RPAAP--AGPSVDPWGGTPAPA-----AGEGPTPDPWGSSDGGV---PVSGPSASDPWTP 457 PA P A P+V P PA A AG P P P GV P G +A+ P P Sbjct: 286 HPAGPPTAAPAVPP----PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAP-AP 340 Query: 458 APAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT--------SGSSAGE 509 P A P T AA G + ++ ALP+ G+ G Sbjct: 341 GVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGL 400 Query: 510 LELLAGEVP---ARSPGAFDMSGVRGSLAEAVGS---PPPAATPT-----PTPPTRKTPE 558 + AG V +R+P A SG+R +L V + P P PT PP Sbjct: 401 PKGAAGAVTQSLSRTPTA-TTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVR 459 Query: 559 SFLG-----PNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT 613 S G P AL + ++ P A P P P S AP Sbjct: 460 SENGQLLMIPQQALAQMQ---AQAHAQPQTTMAPRPATPTSAPPVQISTVQ----APGTP 512 Query: 614 LTLNQLRLSPVPPVPGAPPTYISP---LGGGPGLPPMMPPGPPA 654 + Q+ + + T + P L PG+ P + G A Sbjct: 513 IIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAA 556 >gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] Length = 411 Score = 72.4 bits (176), Expect = 1e-12 Identities = 90/325 (27%), Positives = 122/325 (37%), Gaps = 45/325 (13%) Query: 352 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGP------PVPPAADPWGGPAPTPASGD 405 A A AP P G + AA PT WGGP +P A P GP P P G Sbjct: 50 ASASAPQRGPSG---ILPAAEPTICSLHQAWGGPGCRAQKGIPAALSPGPGPIPAPIPG- 105 Query: 406 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPW 465 PA GP G P P G P P + P+ GP + P P F P Sbjct: 106 ---PAQIPGPLP---GSIPGPIPGPAQIPSPIPA-----PIPGPISGPVQIPGP-FRGPI 153 Query: 466 GGSPAKPSTNGTTAAGGFD-TEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 524 G + P+ +G F P + P SG G + + +P PG Sbjct: 154 PGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISV---PIPGPIPGP 210 Query: 525 FDMSGVRGSLAEAVGSPPPAATPTPT--PPTRKTPESFLGPNAALV--DLDSLVSRPGPT 580 + G ++ P P P P P P GPN L+ + +S PGP Sbjct: 211 -----ISGPISGPNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPI 265 Query: 581 PPGAKASNPFLPGGGPATGPS-VTNPFQPAPPATLTLNQLRLSPVPPVPGAPP---TYIS 636 G S +PG G GP + +P + P +L L+P+ PG+ P + + Sbjct: 266 -IGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLP----GLAPILG-PGSGPGSGSVPA 319 Query: 637 PLGGGPGLPPMMPPGPPAPNTNPFL 661 P+ G LP P P +P+ + FL Sbjct: 320 PIPGPGSLPAPAPLWPQSPDASDFL 344 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/113 (34%), Positives = 45/113 (39%), Gaps = 8/113 (7%) Query: 350 FTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRP 409 F+ P P P P GP P + P P S P GP P + P GP P P G P Sbjct: 171 FSGPNPGPIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGP--IP 228 Query: 410 AAPAGPSVDPWGGT---PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP 459 +GP+ P G P P GP P P G P+ GP S P P Sbjct: 229 GPISGPNPGPIPGPISGPNPGLIPGPIPGP---ISGPGPIIGPIPSPAQIPGP 278 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 72.0 bits (175), Expect = 2e-12 Identities = 91/312 (29%), Positives = 118/312 (37%), Gaps = 51/312 (16%) Query: 365 PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPT--PASGDPWRPAAPAGP------S 416 P+P A P+A + +A P PA + A G P PA P+ P + Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 270 Query: 417 VDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP-APAFSDPWGGSPAKPSTN 475 + P TP P P P SS P++ PS S P +P AP PA P + Sbjct: 271 LRPPQVTP-PRKDAAPALGPLSSS----PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325 Query: 476 GTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLA 535 TT+ G + LP+ L LA P P +L Sbjct: 326 ATTSLGS--------PTLQATHSFLPSP-----PLSPLATPPPQAPPAL--------ALP 364 Query: 536 EAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGG 595 P P A+P +P +P++ PNA V L P P+PP PF P Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQA---PNALAVHLLQAPFSPPPSPP---VQAPFSPPAS 418 Query: 596 PATGPSVTNPFQPAPPATLTLNQLRLSPVPPV-PGAPPTYISPLGGGPGL--PPMM---- 648 P PS T P Q APP +L L++ P PP P P+ P P L PP+ Sbjct: 419 PPVSPSATPPSQ-APP-SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476 Query: 649 -PPGPPAPNTNP 659 P PPA T P Sbjct: 477 PPQAPPALATPP 488 Score = 64.7 bits (156), Expect = 3e-10 Identities = 89/318 (27%), Positives = 116/318 (36%), Gaps = 40/318 (12%) Query: 352 APAPAP-TTDPWGGPAPMAAAVPTAAPTSDPWGGPP-VPPAADPWGGPAPTPASGDPWRP 409 APA P ++ P P+P A P+A P+ PP PP+ +PT + + P Sbjct: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343 Query: 410 AAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP----APAFSDPW 465 + P P P P PA P P S P+S + P P P+ Sbjct: 344 SPPLSPLATPPPQAP-PALALPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401 Query: 466 GGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAF 525 P+ P + P +A P S + L +VP P + Sbjct: 402 SPPPSPPVQAPFSPPASPPVSP----------SATPPS-QAPPSLAAPPLQVPPSPPASP 450 Query: 526 DMSGVRGSLAEAVGSPPPAATP---TPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 582 MS S +PPP A P PP + P P AL + S PG P Sbjct: 451 PMS---PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA--SFPGQAPF 505 Query: 583 GAKASNPFLP--GGGPATGPSVTNPF---QPAPPATLTLNQLRLSPVPPVPGAPPTYISP 637 AS P P P P + P P+PPA+ TL R PP PG P T +S Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---PPTPG-PDTSVS- 560 Query: 638 LGGGPGLPPMMPPGPPAP 655 GP L + PGPP P Sbjct: 561 ---GPRLTLALAPGPPPP 575 Score = 63.5 bits (153), Expect = 6e-10 Identities = 92/320 (28%), Positives = 113/320 (35%), Gaps = 47/320 (14%) Query: 365 PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGG--------PAPTPASGDPWRPAAPAGPS 416 PA A + T P P PPV PAA G P A G + P Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76 Query: 417 VDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS-ASDPWTPAPAFSDPWGGSPAKPSTN 475 P + PA+G G P ++ G PVS P AS P P G + S Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPL-----GQKGLRISAE 130 Query: 476 GTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR-SPGAFDMSGVRGSL 534 T A G P R+AL SAG +G P SP S G+ Sbjct: 131 ETVARGKATEAPK--------RSAL-----SAGARRDTSGPTPGTPSPAMARRSRAAGT- 176 Query: 535 AEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT-------PPGAKAS 587 VG P PA + P PPT +S + S +R P+ P S Sbjct: 177 --EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234 Query: 588 NPFLPGGGPA-TGPSVTN----PFQPAPPATLTLNQLRLSPV-PPVPGAPPTYISPLGGG 641 + P PA +GPS P P+ P L LR V PP A P + PL Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA-LGPLSSS 293 Query: 642 PGLPPMMPPGPPAPNTNPFL 661 P P P PP+P+ P L Sbjct: 294 PLATP-SPSAPPSPSAPPSL 312 Score = 57.4 bits (137), Expect = 4e-08 Identities = 77/314 (24%), Positives = 103/314 (32%), Gaps = 47/314 (14%) Query: 352 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA- 410 +P +P P P+P A P+ PP PP P+ PA P S P+ Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430 Query: 411 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGP----SASDPWTPAPAFSDPWG 466 AP + P P+P A +P P++ P + P P + P Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ 490 Query: 467 GSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA-- 524 P+ P+ + G P L T P + L P SP Sbjct: 491 ALPSPPA----SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546 Query: 525 ----------FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLV 574 +SG R +LA A G PP PP+R + GP DL Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPP--------PPSRSPSSTLSGP-----DLAGHS 593 Query: 575 SRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPV-----PG 629 S TP + + P GG A P PA + P PP+ PG Sbjct: 594 SSATSTPEELRGYDSG-PEGGAAASPPPDAELAACHPAAWS-----RGPAPPLAFRGAPG 647 Query: 630 APPTYISPLGGGPG 643 AP + P GPG Sbjct: 648 APLPW--PPATGPG 659 Score = 39.7 bits (91), Expect = 0.009 Identities = 40/141 (28%), Positives = 50/141 (35%), Gaps = 19/141 (13%) Query: 352 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAAD--PWGGPAPTPASGDPWRP 409 A AP P P P+ + A +S P D P GG A +P Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626 Query: 410 AAPAGPSVDPWGGTPAPAA---GEGPTPDPW------GSSDGGVPVSGPSASDPWTPAPA 460 PA W PAP G P PW GS+DG + + TPAP Sbjct: 627 CHPAA-----WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681 Query: 461 FSDPWGGSPAKPSTNGTTAAG 481 DP P+ ++ G AAG Sbjct: 682 ALDP---GPSPGTSGGKAAAG 699 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 71.6 bits (174), Expect = 2e-12 Identities = 81/329 (24%), Positives = 114/329 (34%), Gaps = 71/329 (21%) Query: 351 TAPAPAPTTD----PWGGPAPMAAAVPTAAPTSDPWGGPPV------PPAADPWGGPAPT 400 T P+P PT+ P P+P T PT+ P PP+ PP P P T Sbjct: 1404 TTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTP--SPPITTTTTPPPTTTP-SPPIST 1460 Query: 401 PASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPA 460 + P +P + P TP+P TP P + S P+ + PA Sbjct: 1461 TTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP------SPPTTTPITPPAST 1514 Query: 461 FSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 520 + P +P+ P+T TT P + PTS ++ P Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-----PTSTTTLP---------PTT 1560 Query: 521 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 580 +P SPPP T TP P T +P + P+ + + P+ Sbjct: 1561 TP-----------------SPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS 1603 Query: 581 PPGA------KASNPFLPGGGPATGPSVTNPF----QPAPPATLTLNQLRLSPVPPVPGA 630 PP + P P P T P+ T P+PP T T +P P + Sbjct: 1604 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT-----TTPPPTTTPS 1658 Query: 631 PPTYISPLGGGPGLPPMMPPGPPAPNTNP 659 PPT +P PP+ P P T P Sbjct: 1659 PPTTTTP------SPPITTTTTPPPTTTP 1681 Score = 65.1 bits (157), Expect = 2e-10 Identities = 75/321 (23%), Positives = 108/321 (33%), Gaps = 56/321 (17%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T P+P PTT P PA PT P+ PP P P+P + P P Sbjct: 1498 TTPSP-PTTTPITPPASTTTLPPTTTPS------PPTTTTTTPPPTTTPSPPTTTPITP- 1549 Query: 411 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP----AFSDPWG 466 P + P TP+P TP P + PS TP+P + P Sbjct: 1550 -PTSTTTLPPTTTPSPPPTTTTTPPP---------TTTPSPPTTTTPSPPTITTTTPPPT 1599 Query: 467 GSPAKPSTNGTTAAGGFDTEPDEFSDFD--RLRTALPTSGSSAGELELLAGEVPARSPGA 524 +P+ P+T TT P + T LP + + + P +P Sbjct: 1600 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP-- 1657 Query: 525 FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDS----LVSRPGPT 580 SPP TP+P T TP P++ + S ++ P PT Sbjct: 1658 ---------------SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPT 1702 Query: 581 P-PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLG 639 P + + P P T P+P T + ++ +PP + P +PL Sbjct: 1703 TTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL- 1761 Query: 640 GGPGLPPMMPPGPPAPNTNPF 660 PP P +PF Sbjct: 1762 ---------PPSITPPTFSPF 1773 Score = 45.1 bits (105), Expect = 2e-04 Identities = 75/338 (22%), Positives = 103/338 (30%), Gaps = 37/338 (10%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3984 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 3985 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4041 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 4042 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4101 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPAATP-------TPTPPTRKTPESFLGPNAALV 568 + P +P + G+ P TP TPTP TP P + Sbjct: 4102 QTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPI 4155 Query: 569 DLDSLVSRPGPTPPGAKA--SNPFLPGGG--PATGPSVTNPFQPAPPATLTLNQLRLSPV 624 + V+ P PTP G + + P P P+ T P +T + +L S Sbjct: 4156 TTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNP 4214 Query: 625 PPVPGAPPT---YISPLGGGPGLPPMMPPGPPAPNTNP 659 PP P T SPL L +PP +T P Sbjct: 4215 PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAP 4252 Score = 43.9 bits (102), Expect = 5e-04 Identities = 73/342 (21%), Positives = 103/342 (30%), Gaps = 42/342 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWR 408 + T P+P TT P ++ T T P PP P TP+ Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM 1744 Query: 409 PAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPA--PAFSDPWG 466 P + P TP P + PT P+ ++ P W + P F P G Sbjct: 1745 TTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGG 1804 Query: 467 GSPAKPSTNGTTAAGGFDTEPDEFSD--FDRLRTALPTSGSSAGELELLAGEVPARSPGA 524 + G A + D +L + S + L+ + G Sbjct: 1805 DTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVS----VGLICKNEDQKPGGV 1860 Query: 525 FDMS-----GVRGSLAEAVGSPPPAATPT---PTPPT------------RKTPESFLGPN 564 M+ + E V P T T PTPPT TP P Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT 1920 Query: 565 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQ 618 + + V+ P PTP G + P P T + P P P T T Sbjct: 1921 TTPITTTTTVT-PTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTT 1973 Query: 619 LRLSPVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 ++P P G +P+ + P P G P T P Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2015 Score = 42.4 bits (98), Expect = 0.001 Identities = 58/284 (20%), Positives = 78/284 (27%), Gaps = 11/284 (3%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 4017 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4076 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 4077 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4133 Query: 462 SDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 521 + P+ T T T PT+ + P + Sbjct: 4134 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4193 Query: 522 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 581 +AE S PP + TP +R T L L + P Sbjct: 4194 QTGPPTHTSTAPIAELTTSNPPPESSTPQT-SRSTSSPLTESTTLLSTLPPAIEMTSTAP 4252 Query: 582 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVP 625 P + GG + P T P P T +P P Sbjct: 4253 PSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTP 4296 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 1924 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1983 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 1984 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2040 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 2041 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2100 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 2101 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2160 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 2161 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2207 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 2208 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2245 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 2039 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2098 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 2099 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 2156 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2215 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 2216 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2275 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 2276 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2322 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2360 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2213 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 2214 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2330 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 2331 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2390 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 2391 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2437 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 2269 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2328 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 2329 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2445 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 2446 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2505 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 2506 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2552 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 2384 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2443 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 2444 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2560 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 2561 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2620 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 2621 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2667 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 2668 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 2499 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2558 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 2559 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2615 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 2616 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2675 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 2676 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2735 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 2736 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2782 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2820 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 2614 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2673 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 2674 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2790 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 2791 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2850 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 2851 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2897 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2788 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 2789 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2905 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 2906 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2965 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 2966 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3012 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 2844 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2903 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 2904 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3020 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 3021 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3080 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 3081 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3127 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3165 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 2959 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3018 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 3019 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3135 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 3136 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3195 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 3196 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3242 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 3243 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 3074 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3133 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 3134 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3250 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 3251 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3310 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 3311 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3357 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 3189 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3248 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 3249 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3365 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 3366 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3425 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 3426 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3472 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 3473 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3510 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 3304 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3363 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 3364 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3420 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3480 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 3481 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3540 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 3541 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3587 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 3419 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3478 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 3479 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3535 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 3536 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3595 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 3596 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3655 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 3656 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3702 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 3703 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3740 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 3534 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3593 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 3594 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3650 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3710 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 3711 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3770 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 3771 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3817 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 3818 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3855 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 3649 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3708 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 3709 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3765 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 3766 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3825 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 3826 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3885 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 3886 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3932 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 3933 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3970 Score = 42.0 bits (97), Expect = 0.002 Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 3764 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3823 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 3824 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3880 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 3881 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3940 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 3941 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4000 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 4001 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 4047 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 P P G +P+ + P P G P T P Sbjct: 4048 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4085 Score = 39.3 bits (90), Expect = 0.012 Identities = 70/337 (20%), Positives = 96/337 (28%), Gaps = 44/337 (13%) Query: 349 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 402 + T PT P G P + T PT P G P P PTP Sbjct: 3879 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3938 Query: 403 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P +V P TP P + PT P ++ P P+ + T P Sbjct: 3939 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3995 Query: 462 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 + P P+T T P T + T+ + Sbjct: 3996 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4055 Query: 516 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 568 + P +P + +P TPTPTP +TP + V Sbjct: 4056 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4115 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 622 P PTP G + P P T + P P P T T ++ Sbjct: 4116 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 4162 Query: 623 PVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNP 659 P P G +P+ + P P P T P Sbjct: 4163 PTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTGP 4197 Score = 38.5 bits (88), Expect = 0.020 Identities = 78/349 (22%), Positives = 111/349 (31%), Gaps = 51/349 (14%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPAS--GDPWR 408 T P+P TT P PT P+S P P P TP+S Sbjct: 1655 TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT 1714 Query: 409 PAAPAGPSVDPWG-GTPAPAAGEGPTPDPWGSSDGGVP---VSGPSASDPWTPA---PAF 461 P++ PS P TP+P TP P ++ +P S P + P P+ P F Sbjct: 1715 PSSTTTPSPPPTTMTTPSPTT----TPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTF 1770 Query: 462 SDPWGGSPAKPSTNGTTAAGGFDTEPDEF----SDFDRLRTAL-PTSGSSAGELELLAGE 516 S +P P G D+ F D + + P ++ + + Sbjct: 1771 SPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPD 1830 Query: 517 VPARSPGAFDMSGVR-GSLAEAVGSPPPAATP------------------TPTPPTRKTP 557 VP G + V G + + P P PT T T Sbjct: 1831 VPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTT 1890 Query: 558 ESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT-- 615 E+ P + + V+ P PTP G + P P T + P P P T T Sbjct: 1891 ENPTPPTTTPITTTTTVT-PTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPT 1943 Query: 616 ----LNQLRLSPVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 ++P P G +P+ + P P G P T P Sbjct: 1944 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992 Score = 36.2 bits (82), Expect = 0.099 Identities = 59/281 (20%), Positives = 84/281 (29%), Gaps = 40/281 (14%) Query: 399 PTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPA 458 PTP + P P TP P + PT P ++ P P+ + T Sbjct: 1893 PTPPTTTPITTTTTVTP-------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1945 Query: 459 PAFS------DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELEL 512 P + P P+T T P T + T+ + Sbjct: 1946 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2005 Query: 513 LAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATP-------TPTPPTRKTPESFLGPNA 565 + P +P + G+ P TP TPTP TP P Sbjct: 2006 TGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTT 2059 Query: 566 ALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQL 619 + + V+ P PTP G + P P T + P P P T T Sbjct: 2060 TPITTTTTVT-PTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTT 2112 Query: 620 RLSPVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 659 ++P P G +P+ + P P G P T P Sbjct: 2113 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 71.6 bits (174), Expect = 2e-12 Identities = 88/355 (24%), Positives = 117/355 (32%), Gaps = 65/355 (18%) Query: 350 FTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPP---AADPWGGPAPTPASGDP 406 F +P T P+ A+ P + P P P PP + P P +P + P Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488 Query: 407 WR---------PAAP---------------AGPSVD-PWGGTPAPAAGEGPTPDPWGSSD 441 + P AP A PS+ P P P+ P Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548 Query: 442 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP 501 P++ P P PAP P P+ +T T P + + P Sbjct: 549 ASAPLTTPHLETPPCPAPC---PLQAPPSPLTTPPPETPSSIATPPPQAPP---ALASPP 602 Query: 502 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFL 561 G + L LA P P +L P P A+P +P +P++ Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXL--------ALPPLQAPPSPPASPPLSPLATPSPQA-- 652 Query: 562 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQ-------------P 608 PNA V L P P+PP PF P P PS T P Q P Sbjct: 653 -PNALAVHLLQAPFSPPPSPP---VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 708 Query: 609 APPATLTLNQLRLSP--VPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFL 661 +PPA+ ++ P PP APP + P P PPM P P P P L Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPP--SPPASPPMSPSATPPPRVPPLL 761 Score = 65.1 bits (157), Expect = 2e-10 Identities = 88/329 (26%), Positives = 108/329 (32%), Gaps = 82/329 (24%) Query: 342 SLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTP 401 +L LA A AP T P P A P AP S P P P TP Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS---------PLTTP---PPETP 584 Query: 402 ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 +S P AP + P G P+P TP P +P P A Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALP-----------PLQAP 633 Query: 462 SDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 521 P P P L T P + ++ L A P S Sbjct: 634 PSPPASPPLSP-----------------------LATPSPQAPNALAVHLLQAPFSPPPS 670 Query: 522 PGAFDMSGVRGSLAEAVGSPP--PAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGP 579 P +A SPP P +P+ TPP++ P SL + P Sbjct: 671 PP-----------VQAPFSPPASPPVSPSATPPSQAPP--------------SLAAPPLQ 705 Query: 580 TPPGAKASNPFLPGGGP---ATGPSVTNPFQ--PAPPATLTLNQLRLSP--VPPVPGAPP 632 PP AS P P P A P P Q P+PPA+ ++ P VPP+ APP Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765 Query: 633 TYISPLGGGPGLPPMMPPGPPAPNTNPFL 661 + P P PM P P P P L Sbjct: 766 LQVPP--SPPASLPMSPLAKPPPQAPPAL 792 Score = 65.1 bits (157), Expect = 2e-10 Identities = 80/311 (25%), Positives = 101/311 (32%), Gaps = 69/311 (22%) Query: 352 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA- 410 +P +P P P+P A P+ PP PP P+ PA P S P+ Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694 Query: 411 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPA 470 AP + P P+P A +P P++ P P P+P S P S Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP--PSPPASPPMSPSAT 752 Query: 471 KPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGV 530 P L A P +VP P + MS Sbjct: 753 PPPR------------------VPPLLAAPPL-------------QVPPSPPASLPMS-- 779 Query: 531 RGSLAEAVGSPPPAATPT-PTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNP 589 + PPP A P TPP + P P A+ PG P AS P Sbjct: 780 ------PLAKPPPQAPPALATPPLQALPS----PPASF---------PGQAPFSPSASLP 820 Query: 590 FLPGGGPA--TGPSVTNPF---QPAPPATLTLNQLRLSPVPPVPGAPPTYISP-----LG 639 P P P + P P+PPA+ TL R PP PG + P L Sbjct: 821 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---PPTPGPDTSVSGPRLTLALA 877 Query: 640 GGPGLPPMMPP 650 GP PP P Sbjct: 878 PGPPPPPSRSP 888 Score = 60.8 bits (146), Expect = 4e-09 Identities = 82/324 (25%), Positives = 110/324 (33%), Gaps = 41/324 (12%) Query: 353 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGP--APTPASGDPWRPA 410 PA P + P P P+A P+A P+ P PPA P P TP P P+ Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTL---PSPPATPPSQAPPSMTTPPMQAP--PS 382 Query: 411 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDP---WTPAPAFSDPWGG 467 P + +P+ P+P S + P+ T +P + Sbjct: 383 LQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT 442 Query: 468 SPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDM 527 SP++P++ T PD L+ L S + L P SP Sbjct: 443 SPSRPAS----------TPPDS----PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488 Query: 528 SGVRGSLAEAVGSPPPAATPTPTPPTRKT--PESFLGPNAALVDLDSLVSRPGPTPPGAK 585 SLA P ++ P T+ + P S P A+L L + P PP Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT-TPPLENLPSLAPP--- 544 Query: 586 ASNPFLPGGGPATGPSVTNPFQPAP--------PATLTLNQLRLSPVPPVPGAPPTYISP 637 P P T P + P PAP P T + S P P APP SP Sbjct: 545 ---PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601 Query: 638 LGGGPGLPPMMPPGPPAPNTNPFL 661 G PP+ P P P P L Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXL 625 Score = 60.1 bits (144), Expect = 6e-09 Identities = 95/347 (27%), Positives = 125/347 (36%), Gaps = 44/347 (12%) Query: 351 TAPAPAP---TTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGG--PAPTPASGD 405 T A AP T P G P P P A G P A+ GG A P S Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75 Query: 406 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS-ASDPWTPAPAFSDP 464 P AG S P PA+G G P ++ G PVS P AS P P Sbjct: 76 RAGPTRSAGTSSRNPASRP-PASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPL---- 129 Query: 465 WGGSPAKPSTNGTTAAGGFDTEPDE--FSDFDRLRTALPTSGSSAGEL---ELLAGE--- 516 G + S T A G P S R T+ PT G+ + + AG Sbjct: 130 -GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188 Query: 517 VPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLG----PNAALVDLDS 572 +P +P A G ++V S +T P+P R+ P + G + +L + Sbjct: 189 LPRPAPSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247 Query: 573 LVSRPGPTPPGAKA--------SNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLS-- 622 +S P + P A+ S P G P VT P + A PA L+ L+ Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307 Query: 623 --------PVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFL 661 PVPP A + L P L +P PP+P+ P L Sbjct: 308 SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354 Score = 56.2 bits (134), Expect = 9e-08 Identities = 77/309 (24%), Positives = 110/309 (35%), Gaps = 40/309 (12%) Query: 352 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWR--P 409 +P +P+ P P AA P P S P PP+ P+A P AP P + P + P Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPP-ASPPMSPSATP-PPQAPPPLAAPPLQVPP 739 Query: 410 AAPAGPSVDPWGGTPA---PAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWG 466 + PA P + P P P P P S +P+S + P P + P Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVP-PSPPASLPMSPLAKPPPQAPPALATPPLQ 798 Query: 467 GSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA-- 524 P+ P++ G P L T P + L P SP Sbjct: 799 ALPSPPAS----FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854 Query: 525 ----------FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLV 574 +SG R +LA A G PPP P+ +P + + G +++ + Sbjct: 855 PRRPPTPGPDTSVSGPRLTLALAPGPPPP---PSRSPSSTLSGPDLAGHSSSATSTPEEL 911 Query: 575 SRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTY 634 P G A++P A P+ + PAPP R +P P+P P T Sbjct: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWSR-GPAPPLA-----FRGAPGAPLPWPPAT- 964 Query: 635 ISPLGGGPG 643 GPG Sbjct: 965 ------GPG 967 Score = 41.2 bits (95), Expect = 0.003 Identities = 80/300 (26%), Positives = 103/300 (34%), Gaps = 49/300 (16%) Query: 353 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAP 412 P+P P + P P +A++P + + P PPV A P+P PAS P P Sbjct: 801 PSP-PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP-PASPTLQAPRRP 858 Query: 413 AGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKP 472 P D P P P P S +SGP D G S + Sbjct: 859 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP-------------DLAGHSSSAT 905 Query: 473 STNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAG---ELELLAGEVPARSPGAFDMSG 529 ST P+E +D + P G++A + EL A A S G Sbjct: 906 ST------------PEELRGYD----SGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA 949 Query: 530 VRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNP 589 RG A P P AT + T GP +A +L P P G KA+ Sbjct: 950 FRG--APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA-- 1005 Query: 590 FLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP------VPGAPPTYISPLGGGPG 643 G G S +P Q A L L L+ S V + A GGGPG Sbjct: 1006 ----AGAGAGASSRSPKQ-ARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG 1060 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 71.2 bits (173), Expect = 3e-12 Identities = 85/360 (23%), Positives = 122/360 (33%), Gaps = 57/360 (15%) Query: 351 TAPAPAPTTDPWGGPA------PMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASG 404 ++P P P + P P P+++++P + PT+ P P P P P ASG Sbjct: 1412 SSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLP--APASAPLTIPISAPLTVSASG 1469 Query: 405 D--------PWRPAAPAG---PSVDPWGGTPAPAA---GEGPTPDPWGSSDGGVPV---- 446 P P PA PS+ P G +P+ +A G P S G P+ Sbjct: 1470 PALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAP 1529 Query: 447 -----------SGPSASDPWTPAPAFSDPWGGSPAKPSTNGT---TAAGGFDTEPDEFSD 492 P+ S PA A + P+ +P + A+ + Sbjct: 1530 TSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAP 1589 Query: 493 FDRLRTA------------LPTSGSSAGELELLAGE---VPARSPGAFDMSGVRGSLAEA 537 +TA LP S G +LA VP +P + G + A Sbjct: 1590 MAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSS--TPGTSLASASP 1647 Query: 538 VGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPA 597 V +P P P+ T P P+ A +L PT G+ S G G Sbjct: 1648 VPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNP 1707 Query: 598 TGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 657 GP T P ++L + + P P PT L P L P P GP +T Sbjct: 1708 QGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHT 1767 Score = 64.3 bits (155), Expect = 3e-10 Identities = 86/343 (25%), Positives = 121/343 (35%), Gaps = 51/343 (14%) Query: 346 LADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 405 L V P P P P P+ +P + S GPP+ PA+ P P P Sbjct: 1019 LGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRP-----PGPVLLP 1073 Query: 406 PWRPAAPAGPSVDP-----WGGT---PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP 457 P +P + + P V P GT P P PTP P S P T Sbjct: 1074 PLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTV 1133 Query: 458 APAFSDPWGGSPAKPSTNGTTAAGGFDT-------EPDEFSDFDRLRTALPTSG-SSAGE 509 P ++ P PA +T TT A T P ++ LP+ S G+ Sbjct: 1134 PPGYTFP----PAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQ 1189 Query: 510 LELLAGEVPARSPGA----FDMSGVRGSLAE------AVGSPPPAATPTPTPPTRKTPES 559 L LA A + G+ F + G + +L AVG P P + Sbjct: 1190 LASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHH 1249 Query: 560 FLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP----PATLT 615 + A + + ++ PGPTP LP P+T P+ T P P T+ Sbjct: 1250 LISQPAHVALIQAVAPTPGPTPVSV------LPSSTPSTTPAPTGLSLPLAANQVPPTMV 1303 Query: 616 LNQ------LRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGP 652 N +R +P + PP +P GLP ++ P P Sbjct: 1304 NNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRP 1346 Score = 52.0 bits (123), Expect = 2e-06 Identities = 83/306 (27%), Positives = 108/306 (35%), Gaps = 59/306 (19%) Query: 364 GPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGT 423 G AP+ + P P+S P GP P P P +P S P + + P P T Sbjct: 1391 GAAPLTISSPLHVPSSLP--GPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVP---T 1445 Query: 424 PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP-----APAFSDPWGGSPAKPSTNGTT 478 PA P P S+ V SGP+ TP PA P +P+ S + + Sbjct: 1446 TLPAPASAPLTIPI-SAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASA 1504 Query: 479 AAGGFDTEPDEFSDFDRLRTAL--PTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAE 536 G T P S L PTS G +A PA SP A Sbjct: 1505 LTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVA---PACSPVLVP--------AS 1553 Query: 537 AVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP 596 A+ SP P+A P P P S L P ++ + P P P Sbjct: 1554 ALASPFPSA-PNPAP----AQASLLAPASSA---------------SQALATPLAPMAAP 1593 Query: 597 ATGPSVTNPFQPAPPATLTLNQLRLSPVP---PVPGAPPTYISPLGGGPGLPPMMPPGPP 653 T ++ P PAPP L+P+P P PGA P S P + P PG Sbjct: 1594 QT--AILAP-SPAPP---------LAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTS 1641 Query: 654 APNTNP 659 + +P Sbjct: 1642 LASASP 1647 Score = 51.6 bits (122), Expect = 2e-06 Identities = 96/350 (27%), Positives = 120/350 (34%), Gaps = 77/350 (22%) Query: 335 TGGKEESSLMDLADVFTAPAPAPTTDPWGGP---APMAAAVPTAAPTSDPWGGPPVPPA- 390 +G +S + L + TAP+ + + P G P AP ++ VP T P P + PA Sbjct: 1496 SGASPSASALTLG-LATAPSLSSSQTP-GHPLLLAPTSSHVPGLNSTVAPACSPVLVPAS 1553 Query: 391 --ADPW-GGPAPTPASGDPWRPAA--------PAGPSVDPWGGTPAPAAGEGPTPDP-WG 438 A P+ P P PA PA+ P P P AP+ P P Sbjct: 1554 ALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLA 1613 Query: 439 SSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTE-PDEFSDFDRLR 497 S G PV S TP P A ST GT+ A P + Sbjct: 1614 PSPGAAPVLASSQ----TPVPVM--------APSSTPGTSLASASPVPAPTPVLAPSSTQ 1661 Query: 498 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAAT----------P 547 T LP S P SP + + +LA +G P+ T P Sbjct: 1662 TMLPAPVPS-----------PLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGP 1710 Query: 548 TPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQ 607 PT TP S L P A +L PGP P G + P P P+ +P Sbjct: 1711 FPTQTLSLTPASSLVPTPA----QTLSLAPGP-PLGPTQTLSLAPA--PPLAPA--SPVG 1761 Query: 608 PAPPATLTL---------------NQLRLSPVPPVPGAPPTYISPLGGGP 642 PAP TLTL L LSP PVP P L P Sbjct: 1762 PAPAHTLTLAPASSSASLLAPASVQTLTLSPA-PVPTLGPAAAQTLALAP 1810 Score = 47.8 bits (112), Expect = 3e-05 Identities = 71/273 (26%), Positives = 99/273 (36%), Gaps = 42/273 (15%) Query: 346 LADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADP-WGGPAPTP--- 401 LA PAP P P + A VP+ P+ + PA P GG +P+ Sbjct: 1642 LASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLS 1701 Query: 402 -ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP- 459 +G+P P S+ PA+ PTP S G P+ GP+ + PAP Sbjct: 1702 LGTGNPQGPFPTQTLSL-------TPASSLVPTPAQTLSLAPGPPL-GPTQTLSLAPAPP 1753 Query: 460 -AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVP 518 A + P G +PA T ++ P +PT G +A + LA Sbjct: 1754 LAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALA-PAS 1812 Query: 519 ARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPG 578 +SP S A ++ A P P + P S P D+L R G Sbjct: 1813 TQSP---------ASQASSLVVSASGAAPLPVTMVSRLPVSKDEP-------DTLTLRSG 1856 Query: 579 PTPPGAKASNPFLPGGGPATGPSVTNPFQPAPP 611 P P + A++ GGP QP PP Sbjct: 1857 PPSPPSTATS----FGGPRPRR------QPPPP 1879 Score = 47.0 bits (110), Expect = 6e-05 Identities = 71/258 (27%), Positives = 100/258 (38%), Gaps = 36/258 (13%) Query: 397 PAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGV--------PVSG 448 P PTP S P++ + P G + AA + P P ++ GV P G Sbjct: 1267 PGPTPVSV---LPSSTPSTTPAPTGLSLPLAANQVP---PTMVNNTGVVKIVVRQAPRDG 1320 Query: 449 PSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAG 508 + P PAP P G PA + T G T R +PT Sbjct: 1321 LTPVPPLAPAPR--PPSSGLPAVLNPRPTLTPGRLPTPT-----LGTARAPMPTPTLVRP 1373 Query: 509 ELELL---AGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNA 565 L+L+ + EV A +PGA ++ + L P PA++P P P +P + + Sbjct: 1374 LLKLVHSPSPEVSASAPGAAPLT-ISSPLHVPSSLPGPASSPMPIP--NSSPLASPVSST 1430 Query: 566 ALVDLDSLVSRPGPTPPGAKASNPF-LPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPV 624 V L S + PT A AS P +P P T + PA LT L+PV Sbjct: 1431 VSVPLSSSLPISVPTTLPAPASAPLTIPISAPLT-------VSASGPALLTSVTPPLAPV 1483 Query: 625 PPVPGAPPTYISPLGGGP 642 P PP+ ++P G P Sbjct: 1484 VPAAPGPPS-LAPSGASP 1500 Score = 38.1 bits (87), Expect = 0.026 Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 21/140 (15%) Query: 522 PGAFDMSGVRGSLAEAVGS---PPPAA--TPTPTPPTRKTPESFLGPNAALVDLDSLVSR 576 PG +RG+ AE G+ P +A T + T P R +P P A R Sbjct: 2391 PGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPA--------PR 2442 Query: 577 PGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYIS 636 P PTP A A+ P L V+ P + P +T+ + + P PP P P S Sbjct: 2443 PRPTPASAPAAIPAL------VPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSS 2496 Query: 637 PLGGGPG--LPPMMPPGPPA 654 P P PP PPA Sbjct: 2497 PACTPPPACTPPPAHTPPPA 2516 Score = 36.2 bits (82), Expect = 0.099 Identities = 80/317 (25%), Positives = 99/317 (31%), Gaps = 36/317 (11%) Query: 353 PAPAPTTDPWGGPAPMAAAVPTAAPTS------DPWGGPPVPPAADPWGGPAPTPASGDP 406 PA AP P P P++A VP +AP PP P P PA TP Sbjct: 2447 PASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACT 2506 Query: 407 WRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS-GPSASDPWTPAPAFSDPW 465 P A P TP+ GP P +S +P+ P A A A + P Sbjct: 2507 -PPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAE---LCAQALASPE 2562 Query: 466 G---GSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 522 S A T+ + D P L + SA L L AG +P Sbjct: 2563 SLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLT-PSAPSLTLEAGSIP---- 2617 Query: 523 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 582 G EA S T T P + P N + + P P Sbjct: 2618 --------NGQEQEAPDS-AEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPL 2668 Query: 583 GA-KASNPFLPGGGPATGPSVTNPFQPAP-PATLTLNQLRLSPVPPVPGAPP-----TYI 635 A + S P + P A A T + SP P P PP + Sbjct: 2669 EADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADV 2728 Query: 636 SPLGGGPGLPPMMPPGP 652 G G G P PPGP Sbjct: 2729 EIRGQGTGRPG-QPPGP 2744 Score = 35.8 bits (81), Expect = 0.13 Identities = 41/146 (28%), Positives = 55/146 (37%), Gaps = 24/146 (16%) Query: 531 RGSLAEAVGSPPPAATPTPT---------PPTRKTPESFLGPNAALVDLDSLVSRPGPTP 581 R L E +P P P P P ++ + + N L + RP P Sbjct: 971 RRVLLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRP---P 1027 Query: 582 PGAKASNPFLPGGGPATGP-----SVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYI- 635 PG + S PG P P S + P PA+ + L P+ P G+ P + Sbjct: 1028 PGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLP 1087 Query: 636 SPLG--GGPGLPPM----MPPGPPAP 655 SPLG G PP + P PPAP Sbjct: 1088 SPLGVLSGTSRPPTPTLSLKPTPPAP 1113 >gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens] Length = 2524 Score = 70.1 bits (170), Expect = 6e-12 Identities = 125/510 (24%), Positives = 178/510 (34%), Gaps = 94/510 (18%) Query: 137 EATSNDPWGPSSSLMSEIADLTYNVVA--FSEIMSMIWKRLNDHGKNWRHVYKAMTLMEY 194 EA S + P S +E+A + N + E M K L +HG+NW + + + Sbjct: 589 EANSEEAITPQQS--AELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMV----- 641 Query: 195 LIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREE 254 GS+ VSQ CK N Y F Y R D+ + + +L+ E Sbjct: 642 ----GSKTVSQ-CK-NFY-------FNYKKRQNLDE--------------ILQQHKLKME 674 Query: 255 RAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEE 314 + + K+K A A + AA PP E ++SG ++EE Sbjct: 675 KERNARRKKKKAPAAASEEAAF----PPVVEDEEMEASGVS--------------GNEEE 716 Query: 315 RIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAP---APTTDPWGGPAPMAAA 371 + + L E + E G +++ + +D + P+P A GP P Sbjct: 717 MVEEAEALHAS-GNEVPRGECSGP--ATVNNSSDTESIPSPHTEAAKDTGQNGPKP---- 769 Query: 372 VPTAAPTSDPWGGPPVPPAADPWGGPAPTPAS---GDPWRPAAPAGPSVDPWGGTPAPAA 428 P P GPP PP D PTPAS G P P AP PS P P Sbjct: 770 -PATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPP-PVVPKEEK 827 Query: 429 GEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPD 488 E P + G P+A + +P + + G A G D E Sbjct: 828 EEETAAAP--PVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEG--PAKGKDAEAA 883 Query: 489 EFSDFDRLRTALPTSGSSAGELELLAG----EVPARSPGAFDMSGVRGSLAEAVGSPPPA 544 E + L+ GS +G + + A ++ G + SP P+ Sbjct: 884 EATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPS 943 Query: 545 -ATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP-GAKASNPFLPGGGPATGPSV 602 TPT P +P+ L DL L R PP K P P + Sbjct: 944 LLTPTGDPRANASPQKPL-------DLKQLKQRAAAIPPIVTKVHEP------PREDAAP 990 Query: 603 TNPFQPAPPATLTLNQLRLSPVPPVPGAPP 632 T P PAPP L S P PG+ P Sbjct: 991 TKPAPPAPPPPQNLQP--ESDAPQQPGSSP 1018 Score = 32.3 bits (72), Expect = 1.4 Identities = 82/357 (22%), Positives = 113/357 (31%), Gaps = 68/357 (19%) Query: 262 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDD 321 +EK +TA A G P A + +G+ E ++ EE + + + Sbjct: 825 EEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAE 884 Query: 322 LRLQMAIEESKRETGG-------------KEESSLMDLADV-----------FTAPAPA- 356 + A++ K+E G +SS AD +P P+ Sbjct: 885 ATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSL 944 Query: 357 --PTTDPWGGPAPM-----------AAAVPT------------AAPTSDPWGGPPVPPAA 391 PT DP +P AAA+P AAPT PP P Sbjct: 945 LTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNL 1004 Query: 392 DPWGGPAPTPAS---GDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSG 448 P P S G PA PA + PA AA P G+P Sbjct: 1005 QPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPV 1064 Query: 449 PS----ASDPWTPAP-AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTS 503 P + P P P AFS G P + T A P S+ P Sbjct: 1065 PPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDT--ARPVLPRPPTISN-------PPPL 1115 Query: 504 GSSAGELELLAGEVPARSPG-AFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPES 559 SSA +L ++ A S G + + A+A P P P P + P S Sbjct: 1116 ISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFS 1172 Score = 32.0 bits (71), Expect = 1.9 Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 5/60 (8%) Query: 578 GPTPPGAKASNPFLPGGGPATGP--SVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYI 635 GP PP ++ P GP T P + P +P P + T P PP P APP + Sbjct: 766 GPKPPATLGADG--PPPGPPTPPPEDIPAPTEPTPASEAT-GAPTPPPAPPSPSAPPPVV 822 Score = 31.6 bits (70), Expect = 2.4 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 3/54 (5%) Query: 608 PAPPATLTLNQLRLSPVPPVPG--APPTYISPLGGGPGLPPMMPPGPPAPNTNP 659 P PPATL + P P P PT +P G P PP PP+P+ P Sbjct: 767 PKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATG-APTPPPAPPSPSAPP 819 Score = 31.2 bits (69), Expect = 3.2 Identities = 45/192 (23%), Positives = 66/192 (34%), Gaps = 30/192 (15%) Query: 449 PSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAG 508 P+A P++ + S G P + TT++ + + D D DR R + ++ Sbjct: 1769 PTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTV 1828 Query: 509 ELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALV 568 E P PG SG GS GS + P + S + P Sbjct: 1829 E------HAPIWRPGTEQSSGSSGSSGGGGGS-----SSRPASHSHAHQHSPISPRTQ-- 1875 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVP 628 D+L RP + N + G + +P+ P L SPV P Sbjct: 1876 --DALQQRP------SVLHNTGMKG--------IITAVEPSTPTVLRSTSTS-SPVRPAA 1918 Query: 629 GAPPTYISPLGG 640 PP PLGG Sbjct: 1919 TFPPATHCPLGG 1930 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 69.3 bits (168), Expect = 1e-11 Identities = 90/320 (28%), Positives = 112/320 (35%), Gaps = 53/320 (16%) Query: 354 APAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA-- 411 +PA P P AAAVPT + P P P +P A P +P PAA Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP--EEPTSPAAAVPTPEEPTSPAAAV 1085 Query: 412 -----PAGPSVD-PWGGTPAPAAGEGPTPDPWGSSDGGVPV----SGPSASDPWTPAPAF 461 P P+ P P A PTP+ S VP + P+A+ P PAF Sbjct: 1086 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAF 1145 Query: 462 SDPWGGSP--------AKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELL 513 P +P A P+ + + P E + F + L S A + Sbjct: 1146 PAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTP 1205 Query: 514 AGEVPA----RSPGA-FDMSGVRGSLAEAVGSP-----PPAATPTPTPPTRK-----TPE 558 A V SP A S SLA AV +P P AA PT PT TPE Sbjct: 1206 AAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPE 1265 Query: 559 SFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQ 618 P A S+ + P P A SN P A P+ P A PA Sbjct: 1266 ELSSPAA------SVPTPEEPASPAAAVSNLEEPASPAAAVPT---PEVAAIPAASV--- 1313 Query: 619 LRLSPVPPVPGAPPTYISPL 638 P P VP P + P+ Sbjct: 1314 ----PTPEVPAIPAAAVPPM 1329 Score = 62.8 bits (151), Expect = 1e-09 Identities = 94/325 (28%), Positives = 120/325 (36%), Gaps = 52/325 (16%) Query: 354 APAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA-- 411 A PT + P AAAVPT + P VPP +P A P +P PAA Sbjct: 1005 AAVPTPEE---PTSPAAAVPTPEEPTSP--AAAVPPPEEPTSPAAAVPTPEEPTSPAAAV 1059 Query: 412 -----PAGPSVD-PWGGTPAPAAGEGPTPDPWGSSDGGVPV----SGPSASDPWTP---- 457 P P+ P P A PTP+ S VP + P+A+ P TP Sbjct: 1060 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-TPEEPA 1118 Query: 458 APAFSDPWGGSPAKPSTNGTT------AAGGFDTEPDEFSDFDRLRTALPTSGSSAGELE 511 +PA + P PA P+ T A T + S A+PT SA Sbjct: 1119 SPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESAS----AAVAVPTPEESASP-- 1172 Query: 512 LLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLD 571 A VP + A + V +L E + P A+ PTP T E F P A Sbjct: 1173 --AAAVPTPAESA-SFAAVVATLEEP--TSPAASVPTPAAMV-ATLEEFTSPAA------ 1220 Query: 572 SLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLS----PVPPV 627 S+ + P A SNP P A P++ P A A LT +L P P Sbjct: 1221 SVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSA-AAVLTPEELSSPAASVPTPEE 1279 Query: 628 PGAPPTYISPLGGGPGLPPMMPPGP 652 P +P +S L P P P P Sbjct: 1280 PASPAAAVSNL-EEPASPAAAVPTP 1303 >gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] Length = 1489 Score = 69.3 bits (168), Expect = 1e-11 Identities = 99/328 (30%), Positives = 116/328 (35%), Gaps = 76/328 (23%) Query: 360 DPWGGPAPMAAAVPTAAP--TSDPWGGPPVPPAADPWGGPAPTPASGD----PWRPAAP- 412 DP G PAP A P+ P S+ W P + PA P+ PA + ASG W P Sbjct: 590 DP-GVPAPQAPQAPSEVPQLVSETWASP-LFPAPRPF--PAQSSASGSFLLSGWDPEGRG 645 Query: 413 AGPSVDPWGGTPAPAAGEGPTPDPW---------GSSDGGVPVS---GPSASDPWTPAPA 460 AG ++ G PA GE T PW GSS G S GPS P P P Sbjct: 646 AGETL---AGDPAEVLGERGTA-PWVEEEEEEEEGSSPGEDSSSLGGGPSRRGP-LPCPL 700 Query: 461 FSDPWGGSPAKPSTNGTTAAG-------GFDTEPDEFSDFDRLRTALPTSGSSAGELELL 513 S G P G AG G P++ S R G L L Sbjct: 701 CSRE-GACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAER----------GSLADL 749 Query: 514 AGEVPARSPGAF--DMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLD 571 PA +P F + G G PP P P P P + P +A+ Sbjct: 750 PMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPG 809 Query: 572 SLVSRPGPTP--PGAKASNPF-----LPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPV 624 S +S PGP P G + PF PGGG A V P R P Sbjct: 810 SGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRP--------------RAPPE 855 Query: 625 PPVPGAPPTYISPLGGGPGLPPMMPPGP 652 PP PGAP P P+ PGP Sbjct: 856 PPDPGAPRP-------PPDPGPLPLPGP 876 Score = 56.2 bits (134), Expect = 9e-08 Identities = 99/381 (25%), Positives = 127/381 (33%), Gaps = 120/381 (31%) Query: 353 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADP------------------W 394 P P P P+ P P A + P S P+ P ADP W Sbjct: 451 PPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLW 510 Query: 395 -----------GGPAPTPASGDPWRPAAPAGP--------SVDPWGGTPAPAAGE----- 430 G PA PAS P A P+ P SV P +P+ Sbjct: 511 EKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIR 570 Query: 431 ----GPTPDP-----WGSSDGGVPV----SGPS-----ASDPWTPAPAFSDPWGGSPAKP 472 G P+P W D GVP PS S+ W +P F P PA+ Sbjct: 571 LEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWA-SPLFPAP-RPFPAQS 628 Query: 473 STNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRG 532 S +G+ G+D E G AGE LAG+ PA ++ G RG Sbjct: 629 SASGSFLLSGWDPE-----------------GRGAGET--LAGD-PA------EVLGERG 662 Query: 533 SLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP------PGAKA 586 + P + E P L SR GP P GA + Sbjct: 663 T--------------APWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACS 708 Query: 587 SNPFLPG---GGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVP--GAPPTYISPLGG- 640 P G G P++ P P ++L + L+ +P P APP ++ PL G Sbjct: 709 CLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGA 768 Query: 641 ------GPGLPPMMPPGPPAP 655 G G PP PP PP P Sbjct: 769 AAPQYPGRGPPPAPPPPPPPP 789 Score = 50.8 bits (120), Expect = 4e-06 Identities = 76/283 (26%), Positives = 92/283 (32%), Gaps = 54/283 (19%) Query: 388 PPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAG--EGPTPDPWGSSDGGVP 445 PP PW P P + + W PA P G PAP P P SS G Sbjct: 1047 PPETGPWRAPGPWEKTPESWGPA--------PTIGEPAPETSLERAPAPSAVVSSRNG-- 1096 Query: 446 VSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGS 505 G +A P PAP NGT G P E R A Sbjct: 1097 --GETAPGPLGPAP--------------KNGTLEPGTERRAP-ETGGAPRAPGAGRLDLG 1139 Query: 506 SAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATP----------TPTPPTRK 555 S G + G P PG+ + G + PPP P P PP + Sbjct: 1140 SGGRAPVGTGTAPGGGPGS-GVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRAR 1198 Query: 556 ---TPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQ---PA 609 PE G + D+ +S G PP + P +P GP N Q Sbjct: 1199 PEVAPEGEPGAPDSRAGGDTALSGDG-DPPKPERKGPEMPRLFLDLGPPQGNSEQIKARL 1257 Query: 610 PPATLTLNQLRLSPVP-PVPGAPPTYISPLG------GGPGLP 645 +L L L L+P P P P PP + G GG G P Sbjct: 1258 SRLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAP 1300 Score = 45.1 bits (105), Expect = 2e-04 Identities = 93/391 (23%), Positives = 118/391 (30%), Gaps = 87/391 (22%) Query: 339 EESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPP--------- 389 E SL DL A AP DP G AA P GPP P Sbjct: 742 ERGSLADLPMAPPASAPPEFLDPLMG----------AAAPQYPGRGPPPAPPPPPPPPRA 791 Query: 390 AADPWGGPAPTPASGDPWRPAAPAGPSVDPWG-GTPAPAAGEGPTPDPWGSSDGGV--PV 446 ADP P P A P + GP G T P + EG P + + GV P Sbjct: 792 PADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPR 851 Query: 447 SGPSASDPWTPAPAFSD---PWGGSPAKPS------------------------TNGTTA 479 + P DP P P P G KP+ G TA Sbjct: 852 APPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATA 911 Query: 480 -------AGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPA------RSPGAFD 526 AG ++ +R T L +G A L L V R+PG + Sbjct: 912 RETGPRKAGRGPGNREKVPGLNRDPTVL-GNGKQAPSLSLPVNGVTVLENGDQRAPGIEE 970 Query: 527 MSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKA 586 + G+L TPP R+ G + + ++ G TPP K+ Sbjct: 971 KAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPP--KS 1028 Query: 587 SNPFLPGGG----------PATGP--------SVTNPFQPAPPATLTLNQLRLSPVPPVP 628 + GG P TGP + PAP + L P Sbjct: 1029 EDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAP--- 1085 Query: 629 GAPPTYISPLGGGPGLPPMMPPGPPAPNTNP 659 AP +S GG P + P P P Sbjct: 1086 -APSAVVSSRNGGETAPGPLGPAPKNGTLEP 1115 Score = 44.7 bits (104), Expect = 3e-04 Identities = 75/335 (22%), Positives = 92/335 (27%), Gaps = 68/335 (20%) Query: 353 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAP 412 P P P P + A P A P P G P P + GG GDP +P Sbjct: 1175 PPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRA--GGDTALSGDGDPPKPERK 1232 Query: 413 AGPSVD--------PWGG------------------TPAPAAGEGPTPDPWGSSDGGVPV 446 GP + P G T P G GP PW +D G Sbjct: 1233 -GPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGA-- 1289 Query: 447 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS 506 +G A P PA D G D + DE D + Sbjct: 1290 AGGEAGGAGAPGPAEED------------------GEDEDEDEEEDEEAAAPGAAAGPRG 1331 Query: 507 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPT------------- 553 G V S A +RG L G+ P + Sbjct: 1332 PGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLF 1391 Query: 554 -RKTPESFLGPNAALV-DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVT----NPFQ 607 ++TP + L A D D PTPP P G S P Sbjct: 1392 DQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLL 1451 Query: 608 PAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 642 P P L ++ +SP PG P GP Sbjct: 1452 PPPGPPLCFSRFSVSPALETPGPPARAPDARPAGP 1486 Score = 43.5 bits (101), Expect = 6e-04 Identities = 95/402 (23%), Positives = 114/402 (28%), Gaps = 97/402 (24%) Query: 324 LQMAIEESKRETGGKEES---SLMDLADVFTAPAPAPTTDPWGGPAP----MAAAVPTAA 376 L+ E ETGG + +DL AP T P GGP A V Sbjct: 1113 LEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTA-PGGGPGSGVDAKAGWVDNTR 1171 Query: 377 PTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPD- 435 P P PP P A PAP A + P P G T G+ P P+ Sbjct: 1172 PQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPER 1231 Query: 436 --------------PWGSSD----------------GGVPVSGPS-ASDPWTPAPAFSDP 464 P G+S+ P GP PW A A + Sbjct: 1232 KGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGAA- 1290 Query: 465 WGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 524 GG G G D + DE D + G V S A Sbjct: 1291 -GGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADA 1349 Query: 525 FDMSGVRGSLAEAVGSPPP------------------------AATPTPTPPTRKTPESF 560 +RG L G+ P TPT + PE Sbjct: 1350 DAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEG- 1408 Query: 561 LGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGG-PATGPSVTNPFQPAPPATLTLNQL 619 D D PTPP +P PG G P+ F+ A Sbjct: 1409 --------DTDPSTPPAPPTPP-----HPATPGDGFPSNDSGFGGSFEWAED-------- 1447 Query: 620 RLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPP--APNTNP 659 P+ P PG PP S P L PGPP AP+ P Sbjct: 1448 --FPLLPPPG-PPLCFSRFSVSPALE---TPGPPARAPDARP 1483 >gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo sapiens] Length = 245 Score = 69.3 bits (168), Expect = 1e-11 Identities = 91/307 (29%), Positives = 114/307 (37%), Gaps = 77/307 (25%) Query: 341 SSLMDLADVFTAPAPAPT-----TDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWG 395 S LAD +PA T T P G P P P S+PW P P + Sbjct: 2 SDEFSLADALPEHSPAKTSAVSNTKP-GQP-------PQGWPGSNPWNNPSAPSSVPSGL 53 Query: 396 GPAPTPASGDPWRPAAPAG--PSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASD 453 P+ TP++ P+ PA P G PSV P G P P P P+ P SGPS Sbjct: 54 PPSATPSTV-PFGPA-PTGMYPSVPPTGPPPGP-------PAPF-------PPSGPSCPP 97 Query: 454 PWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELL 513 P P PA P+ G G + T F + R A PT ++AG L Sbjct: 98 PGGPYPA-----------PTVPGPGPTGPYPTPNMPFPELPRPYGA-PTDPAAAGPLG-- 143 Query: 514 AGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSL 573 P S + + G P P+ P P PP + P + P Sbjct: 144 ----PWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGA--APPVPW------ 191 Query: 574 VSRPGPTPPGA---KASNPFLPGGGPATG--PSVTNPFQ-PAPPATLTLNQLRLSPVPPV 627 G PPGA A P G P G P+ +NPFQ P+ P S PP+ Sbjct: 192 ----GTVPPGAWGPPAPYPAPTGSYPTPGLYPTPSNPFQVPSGP----------SGAPPM 237 Query: 628 PGAPPTY 634 PG P +Y Sbjct: 238 PGGPHSY 244 Score = 42.7 bits (99), Expect = 0.001 Identities = 51/188 (27%), Positives = 66/188 (35%), Gaps = 31/188 (16%) Query: 488 DEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATP 547 DEFS D L P S+ + G+ P PG+ + + G PP +ATP Sbjct: 3 DEFSLADALPEHSPAKTSAVSNTK--PGQPPQGWPGSNPWNNPSAPSSVPSGLPP-SATP 59 Query: 548 TPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQ 607 + P P + PGP P + P GGP P+V P Sbjct: 60 STVPFGP-------APTGMYPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGP 112 Query: 608 PAPPATLTLNQLRLSPVPPVP---GAP--PTYISPLG------GGPGLPPM----MPPGP 652 P T + P P +P GAP P PLG GP P M P Sbjct: 113 TGPYPTPNM------PFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNM 166 Query: 653 PAPNTNPF 660 P P+ P+ Sbjct: 167 PYPSPGPY 174 Score = 40.0 bits (92), Expect = 0.007 Identities = 41/135 (30%), Positives = 49/135 (36%), Gaps = 23/135 (17%) Query: 542 PPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPF----LPGGGPA 597 PP P P PP+ + GP A V PGPT P + PF P G P Sbjct: 80 PPPGPPAPFPPSGPSCPPPGGPYPA-----PTVPGPGPTGPYPTPNMPFPELPRPYGAP- 133 Query: 598 TGPSVTNPFQP-----APPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPP-----M 647 T P+ P P + P + +P P P P P PG P Sbjct: 134 TDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGAAPPVPWGT 193 Query: 648 MPP---GPPAPNTNP 659 +PP GPPAP P Sbjct: 194 VPPGAWGPPAPYPAP 208 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 68.6 bits (166), Expect = 2e-11 Identities = 97/356 (27%), Positives = 122/356 (34%), Gaps = 69/356 (19%) Query: 338 KEESSLMDLADVFTAPAPAPTTDPWGGPA--PMAAAVPTAAPTSDPWGGPPVPPAADPWG 395 KE SLM A++ AP PA + GPA P+A+A AAP ++P PP+ Sbjct: 311 KEYLSLM--AELGEAPVPA-SVGSTSGPATTPLASAPRPAAPANNP-----PPPSL---- 358 Query: 396 GPAPTPASGDPWRPAAPAG--PSVDPWGGTPA-PAAGEGPTPDPWGSSDGGVPVSGPSAS 452 T S PW + P+ P GG P P G P P S GG P Sbjct: 359 --MSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHG-GHPMQH 415 Query: 453 DPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELEL 512 +P P P PW P P G G P D+ + P GS L Sbjct: 416 NPNGPPP----PWMQPPPPPMNQGPHPPGHHGPPP-----MDQYLGSTPV-GSGVYRLHQ 465 Query: 513 LAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAAT-------------PTPTPPTRKTPES 559 G +P G S G PPP + P P PP+ S Sbjct: 466 GKGMMPPPPMGMMPPPPPPPS-----GQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASS 520 Query: 560 FLGPNAALVDLDSLVSRPGPTPP------------------GAKASNPFLPGGGPATGPS 601 P + + G PP G P PG P P Sbjct: 521 TPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPG 580 Query: 602 VTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLG-GGPGLPPM-MPPGPPAP 655 P P PP + + P PP P P +++ +G G G+PP MPP PP P Sbjct: 581 APPPPPPPPPGSAGM-MYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPP 635 Score = 31.6 bits (70), Expect = 2.4 Identities = 28/93 (30%), Positives = 31/93 (33%), Gaps = 13/93 (13%) Query: 352 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPP-----AADPWGGPAPTPASGDP 406 A A +P G M P P P PP PP A + P P P DP Sbjct: 550 AAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDP 609 Query: 407 WRPAAPAGPSV---DPWGGTPAPAAGEGPTPDP 436 G V P+G PAP P P P Sbjct: 610 SNFVTMMGMGVAGMPPFGMPPAP-----PPPPP 637 >gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens] Length = 2462 Score = 67.8 bits (164), Expect = 3e-11 Identities = 142/578 (24%), Positives = 201/578 (34%), Gaps = 119/578 (20%) Query: 137 EATSNDPWGPSSSLMSEIADLTYNVVA--FSEIMSMIWKRLNDHGKNWRHVYKAMTLMEY 194 EA S + P S +E+A + N + E M K L +HG+NW + + + Sbjct: 589 EANSEEAITPQQS--AELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMV----- 641 Query: 195 LIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREE 254 GS+ VSQ CK N Y F Y R D+ + + +L+ E Sbjct: 642 ----GSKTVSQ-CK-NFY-------FNYKKRQNLDE--------------ILQQHKLKME 674 Query: 255 RAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS--SGEEELQLQLALAMSKEEADQ 312 + + K+K A A + AA PP ++ S SG EE ++ A A +D Sbjct: 675 KERNARRKKKKAPAAASEEAAF---PPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDT 731 Query: 313 EERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAV 372 E + E+ ++TG L P P PT P PAP Sbjct: 732 ES---------IPSPHTEAAKDTGQNGPKPPATLGADGPPPGP-PTPPPEDIPAPTE--- 778 Query: 373 PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGE-- 430 PT P S+ G P PPA P P + A A P V+ PAA E Sbjct: 779 PT--PASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETA-AAPPVEEGEEQKPPAAEELA 835 Query: 431 ---GPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSD------------------PWGGSP 469 G +P S GP+ A A ++ G+P Sbjct: 836 VDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAP 895 Query: 470 AKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGE----------LELLAGEVPA 519 ++ T +A D E D +RL + P+ + G+ L+L + A Sbjct: 896 QDSDSSATCSADEVDEA--EGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRA 953 Query: 520 RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGP 579 + ++ V E +P A P P PP PES S P Sbjct: 954 AAIPPIQVTKVHEPPREDA-APTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRS---P 1009 Query: 580 TPPGAK-ASNPF-----------LPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPV 627 PP K A P LPG P + PF P PP + ++ SP P Sbjct: 1010 APPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGL--PF-PVPPREV----IKASPHAPD 1062 Query: 628 PGA----PPTYISPLGGGPGLPPMMPPGPPAPNTNPFL 661 P A PP + PLG P++P P N P + Sbjct: 1063 PSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLI 1100 Score = 32.0 bits (71), Expect = 1.9 Identities = 82/358 (22%), Positives = 113/358 (31%), Gaps = 69/358 (19%) Query: 262 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDD 321 +EK +TA A G P A + +G+ E ++ EE + + + Sbjct: 808 EEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAE 867 Query: 322 LRLQMAIEESKRETGG-------------KEESSLMDLADV-----------FTAPAPA- 356 + A++ K+E G +SS AD +P P+ Sbjct: 868 ATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSL 927 Query: 357 --PTTDPWGGPAPM-----------AAAVPT-------------AAPTSDPWGGPPVPPA 390 PT DP +P AAA+P AAPT PP P Sbjct: 928 LTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQN 987 Query: 391 ADPWGGPAPTPAS---GDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS 447 P P S G PA PA + PA AA P G+P Sbjct: 988 LQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFP 1047 Query: 448 GPS----ASDPWTPAP-AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT 502 P + P P P AFS G P + T A P S+ P Sbjct: 1048 VPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDT--ARPVLPRPPTISN-------PPP 1098 Query: 503 SGSSAGELELLAGEVPARSPG-AFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPES 559 SSA +L ++ A S G + + A+A P P P P + P S Sbjct: 1099 LISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFS 1156 Score = 31.2 bits (69), Expect = 3.2 Identities = 45/192 (23%), Positives = 66/192 (34%), Gaps = 30/192 (15%) Query: 449 PSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAG 508 P+A P++ + S G P + TT++ + + D D DR R + ++ Sbjct: 1753 PTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTV 1812 Query: 509 ELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALV 568 E P PG SG GS GS + P + S + P Sbjct: 1813 E------HAPIWRPGTEQSSGSSGSSGGGGGS-----SSRPASHSHAHQHSPISPRTQ-- 1859 Query: 569 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVP 628 D+L RP + N + G + +P+ P L SPV P Sbjct: 1860 --DALQQRP------SVLHNTGMKG--------IITAVEPSTPTVLRSTSTS-SPVRPAA 1902 Query: 629 GAPPTYISPLGG 640 PP PLGG Sbjct: 1903 TFPPATHCPLGG 1914 >gi|149158690 HLA-B associated transcript-2 [Homo sapiens] Length = 2157 Score = 67.8 bits (164), Expect = 3e-11 Identities = 101/430 (23%), Positives = 142/430 (33%), Gaps = 96/430 (22%) Query: 283 EAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESS 342 E + W + E + +L + ++ D +E G + EE E GK+ +S Sbjct: 321 ENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNS 380 Query: 343 LMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGP-PVPPAADP-------W 394 P ++P P P A T+ P G P P PP P W Sbjct: 381 --------------PNSEP---PTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNW 423 Query: 395 GGPAPTP-ASGDPWRPAAPAGPSVDPWGGTPAPAAGE----------------------- 430 G P P G P +P AP + W ++ E Sbjct: 424 GPPGDYPDRGGPPCKPPAPEDED-EAWRQRRKQSSSEISLAVERARRRREEEERRMQEER 482 Query: 431 --------GPTPDPWGSSDGGV---PVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTA 479 + +G+ D + P + P+A P PA PA P + T Sbjct: 483 RAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTP 542 Query: 480 AGGFDTEPDEFSDFDRLRTALPTSG-SSAGELELLAGEVPARSPGAFDMSGVRGSLAEAV 538 +TEP+E + ++ PT G ++A L G + S G+F+ S V L Sbjct: 543 ----ETEPEEPAQAPPAQST-PTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKE 597 Query: 539 GSPPPAATPTPTP--------------PTRKTPESFLGPNAALVDLDSLVSRPGPTPPGA 584 G PP P PT PTR+ P LG L R Sbjct: 598 GPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLK 657 Query: 585 KAS----NPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGG 640 + G P T P P+PP +TL + P P P PP + P G Sbjct: 658 QQQQHQWQQHQQGSAPPT------PVPPSPPQPVTLGAV---PAPQAPPPPPKALYP--G 706 Query: 641 GPGLPPMMPP 650 G PP MPP Sbjct: 707 ALGRPPPMPP 716 Score = 66.2 bits (160), Expect = 9e-11 Identities = 109/422 (25%), Positives = 143/422 (33%), Gaps = 78/422 (18%) Query: 281 PPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEE 340 P + ++AW Q + ++ LA+ ++ ++EER R + R E+ KR Sbjct: 442 PEDEDEAWRQRRKQSSSEISLAVERARRRREEEER--RMQEERRAACAEKLKR------- 492 Query: 341 SSLMDLADVFTAPAPAPTTDPWGGP-APMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 399 L + F AP +P P AP A P A P P PP PP A AP Sbjct: 493 -----LDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELP--APPAPPPAS-----AP 540 Query: 400 TPASGDPWRPA-APAGPSVDPWGGTPAP--AAGEGPTPDPWGSSDGGVPVSGPSASDPWT 456 TP + +P PA AP S G AP +G G T S PV P Sbjct: 541 TPET-EPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVE-PQLPSKEG 598 Query: 457 PAPAFSDPWGGSPAKPSTNGT-TAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 515 P P P +P P G P + + + + +LP + +LL Sbjct: 599 PEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQ 658 Query: 516 E-----------------VPARSPGAFDMSGVRGSLAEAVGSPPPAA-------TPTPTP 551 + VP P + V A PPP A P P P Sbjct: 659 QQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVP---APQAPPPPPKALYPGALGRPPPMP 715 Query: 552 PTRKTPESFLGPNAALVDLDSLVSRPGPT--PPGAKASNPFLPGGGPATGPSVTNPFQPA 609 P P + P VD L RP PPG S +P +G S + PF Sbjct: 716 PMNFDPRWMMIP--PYVDPRLLQGRPPLDFYPPGVHPSG-LVPRERSDSGGSSSEPFDRH 772 Query: 610 PPATLTLNQLRLSPVPP-----------VPGAPPTYISPL-----GGGPGLPPMMPPGPP 653 PA L + PV P P P SPL G+ PP PP Sbjct: 773 APA--MLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPP 830 Query: 654 AP 655 P Sbjct: 831 PP 832 Score = 39.7 bits (91), Expect = 0.009 Identities = 76/303 (25%), Positives = 103/303 (33%), Gaps = 60/303 (19%) Query: 376 APTSDPWGGPPVPPAADPWGGPAPTPASG-DPWRPAA---------PAGPSVDPWGGTPA 425 AP P P +P A GP+P P + +P R + GP V GGTP Sbjct: 1492 APGGHPRHKPGLPQAPQ---GPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPR 1548 Query: 426 PAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDT 485 +AG P P P + P P S G P P + G T Sbjct: 1549 DSAGVSPFPPKRRERP---PRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTG--T 1603 Query: 486 EPDEFSDFDRLRTALPTSGSSAGELEL----------LAGEVPARSPGAFDMSGVRGSLA 535 E ++RL TA +E +AG ++S D+SG Sbjct: 1604 EALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSG-----D 1658 Query: 536 EAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGG 595 V S P + +P + E GP RPG + P Sbjct: 1659 SQVSSGPCSQRSSPDGGLKGAAE---GP----------PKRPGGSSP---------LNAV 1696 Query: 596 PATGPSVTNPFQPAPPATLTLNQLRL---SPVPPVP-GAPPTYISPLGGGPG-LPPMMPP 650 P GP + P + PPA ++ L P+PP P G + + G PG + P P Sbjct: 1697 PCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRP 1756 Query: 651 GPP 653 GPP Sbjct: 1757 GPP 1759 Score = 38.1 bits (87), Expect = 0.026 Identities = 81/341 (23%), Positives = 104/341 (30%), Gaps = 70/341 (20%) Query: 355 PAPTTDPWGGPAPMAAAV-PTAAPTSDPWGGPPVPPAADP------------------W- 394 P PTT P P + PT P S G P + P W Sbjct: 606 PPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQ 665 Query: 395 ----GGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS 450 G PTP P +P G PAP A P + + G P P Sbjct: 666 QHQQGSAPPTPVPPSPPQPVT--------LGAVPAPQAPPPPPKALYPGALGRPPPMPPM 717 Query: 451 ASDP-WTPAPAFSDP---WGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS 506 DP W P + DP G P G +G P E SD SG S Sbjct: 718 NFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSG---LVPRERSD----------SGGS 764 Query: 507 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 566 + E R G + + + + P P +P + E G + Sbjct: 765 SSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSE 824 Query: 567 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTN-PFQPAPPATLT----LNQLRL 621 + P P PP AS P P G A GP ++ P + P L +++ Sbjct: 825 --------TPPVPPPPPYLASYPGFPENG-APGPPISRFPLEEPGPRPLPWPPGSDEVAK 875 Query: 622 SPVPPVPGAPPTYISPLGGGP--GLPPMM-----PPGPPAP 655 PP PP + GP G P GPP P Sbjct: 876 IQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPP 916 Score = 38.1 bits (87), Expect = 0.026 Identities = 78/301 (25%), Positives = 100/301 (33%), Gaps = 65/301 (21%) Query: 368 MAAAVPTAAPTSDPWGG-PPVPPAADPW------GGPAPTPAS-GDPWRPAA---PAGPS 416 + A+V A P S W P +A+P G P P+S G P AGPS Sbjct: 1785 LTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPS 1844 Query: 417 VDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNG 476 G G + GG PS P+ P + P G +P +G Sbjct: 1845 SSQISG--------GAMDSQLHPNSGGFRPGTPSLH-PYRSQPLYLPP-GPAPPSALLSG 1894 Query: 477 TTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAE 536 G +F DF ++ A EL L P +F S Sbjct: 1895 LALKG-------QFLDFSTMQ---------ATELGKLPAGGVLYPPPSFLYS-------- 1930 Query: 537 AVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP 596 PA P+P P T S L L S P PG ++ FLP G P Sbjct: 1931 ------PAFCPSPLPDT-----SLLQVRQDLPSPSDFYSTP--LQPGGQSG--FLPSGAP 1975 Query: 597 ATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPN 656 A + P +N L P PP P PP + P+G P + PPAP Sbjct: 1976 AQQMLLPMVDSQLP----VVNFGSLPPAPP-PAPPPLSLLPVGPALQPPSLAVRPPPAPA 2030 Query: 657 T 657 T Sbjct: 2031 T 2031 Score = 36.6 bits (83), Expect = 0.076 Identities = 72/280 (25%), Positives = 87/280 (31%), Gaps = 53/280 (18%) Query: 346 LADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 405 + DVFTA P P P AA S+ PPVPP P P AS Sbjct: 792 VGDVFTATPAEPR--PLTSPLRQAADEDDKGMRSET---PPVPP-------PPPYLASYP 839 Query: 406 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPW--GSSDGGVPVSGPSASDPWTPAPAFSD 463 + GP + + P GP P PW GS + + P +P P + Sbjct: 840 GFPENGAPGPPISRF-----PLEEPGPRPLPWPPGSDEVAKIQTPPPKKEP--PKEETAQ 892 Query: 464 PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPG 523 G + G +GG P R P GSS Sbjct: 893 LTGPEAGRKPARGV-GSGGQGPPPPRRESRTETRWG-PRPGSSR---------------- 934 Query: 524 AFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPG 583 RG E G+PP A P PP E P L D P P P Sbjct: 935 -------RGIPPEEPGAPPRRAGPIKKPPPPTKVEEL--PPKPLEQGDETPKPPKPDP-- 983 Query: 584 AKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSP 623 K + L GGP P N PAP + R+ P Sbjct: 984 LKITKGKL--GGPKETPPNGN-LSPAPRLRRDYSYERVGP 1020 Score = 35.0 bits (79), Expect = 0.22 Identities = 77/307 (25%), Positives = 101/307 (32%), Gaps = 73/307 (23%) Query: 334 ETGGKEESSLMDLADVFTAPAPAPTTDP-----W---GGPAPMAAAVPTAA--PTSDPWG 383 + G ++ + + + P P+ P W GG P P + DP G Sbjct: 174 QAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRG 233 Query: 384 G--PPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSD 441 G P PP P+ G P P P+ P P P +GP P Sbjct: 234 GLQPSGPPQFPPYRGMMP-PFMYPPYLPFPP-------------PYGPQGPYRYPTPDGP 279 Query: 442 GGVP-VSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTAL 500 P V+GP S P +P G +PS + D +FD+L Sbjct: 280 SRFPRVAGPRGSGP---PMRLVEPVG----RPSI----------LKEDNLKEFDQLDQEN 322 Query: 501 PTSGSSAGE----LELL--AGEVPARSPGAFDMSGVRGSLAEAVGSPPPAA------TPT 548 + A E E L + E R G R S + + PP A +P Sbjct: 323 DDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPN 382 Query: 549 PTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL--PGGGPA--TGPSVTN 604 PPT KT + SRP T PG A P L P GPA GP Sbjct: 383 SEPPTPKTAWAE-------------TSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDY 429 Query: 605 PFQPAPP 611 P + PP Sbjct: 430 PDRGGPP 436 Score = 33.9 bits (76), Expect = 0.49 Identities = 54/220 (24%), Positives = 71/220 (32%), Gaps = 19/220 (8%) Query: 447 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGS- 505 S P +SD T P S P S S + P S A T G+ Sbjct: 93 SDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAH 152 Query: 506 -SAGELELLAG-----EVPA-RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTR---- 554 G L E P ++ G D + AE P P+ P + R Sbjct: 153 GDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGG 212 Query: 555 KTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL 614 + P+ GP++ L R G P G P+ P P P+ P PP Sbjct: 213 RGPDELEGPDSKLHHGHD--PRGGLQPSGPPQFPPYRGMMPPFMYP----PYLPFPPPYG 266 Query: 615 TLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPA 654 R P P P P P G GP + + P G P+ Sbjct: 267 PQGPYRY-PTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPS 305 Score = 33.9 bits (76), Expect = 0.49 Identities = 66/271 (24%), Positives = 83/271 (30%), Gaps = 26/271 (9%) Query: 321 DLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSD 380 D A E K GG L P+P P T V P+ Sbjct: 1903 DFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTS--------LLQVRQDLPSPS 1954 Query: 381 PWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSS 440 + P+ P P+ PA P V+ PAP P P P Sbjct: 1955 DFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPP----PAPPPLSLL 2010 Query: 441 DGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTAL 500 G + PS + PAPA SPA+P A E F D+ +L + L Sbjct: 2011 PVGPALQPPSLAVRPPPAPATRVL--PSPARPFPASLGRAELHPVELKPFQDYQKLSSNL 2068 Query: 501 --------PTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPP 552 P +G S L P+ G F V SPP A P P Sbjct: 2069 GGPGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVD---LYQQASPPDALRWIPKPW 2125 Query: 553 TRKTPESFLGPNAALVDLDSLVSR-PGPTPP 582 R P GP+ + S + PG PP Sbjct: 2126 ERTGPPPREGPSRRAEEPGSRGDKEPGLPPP 2156 Score = 31.2 bits (69), Expect = 3.2 Identities = 35/113 (30%), Positives = 41/113 (36%), Gaps = 26/113 (23%) Query: 539 GSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPAT 598 GS PPA P P PP P +GP + SL RP P P + LP Sbjct: 1994 GSLPPAPPPAP-PPLSLLP---VGP---ALQPPSLAVRPPPAP-----ATRVLPS----- 2036 Query: 599 GPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG 651 PA P +L + L PV P +S GGPG P G Sbjct: 2037 ---------PARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTG 2080 Score = 30.0 bits (66), Expect = 7.1 Identities = 71/269 (26%), Positives = 91/269 (33%), Gaps = 49/269 (18%) Query: 398 APTPASGDPWR-PAAPAGPSVDPWGGTPAPA---AGEGPTPDPWG-----SSDGGVPVSG 448 APTP G + P AP P P +PAPA A G P G GG P Sbjct: 1124 APTPKEGTLTQVPLAPPPPGAPP---SPAPARFTARGGRVFTPRGVPSRRGRGGGRPP-- 1178 Query: 449 PSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAG 508 P W+P PA S +P KP T + EP + + + GS+ G Sbjct: 1179 PQVCPGWSP-PAKSL----APKKPPTGPLPPS----KEPLKEKLIPGPLSPVARGGSNGG 1229 Query: 509 E-LELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPP----------AATPTPTPPTRKTP 557 + + GE P R R A+ PP AA + P+ P Sbjct: 1230 SNVGMEDGERPRRR---------RHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLP 1280 Query: 558 ESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLN 617 S GP AL + P P A A +P L + T Sbjct: 1281 ASAPGPEEALTTVTV-----APAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERR 1335 Query: 618 QLRLSPVPPVPGAPPTYISPLGGGPGLPP 646 + +P PPV P +P GGG G P Sbjct: 1336 GDKEAP-PPVLLTPKAVGTPGGGGGGAVP 1363 Score = 29.6 bits (65), Expect = 9.3 Identities = 42/169 (24%), Positives = 63/169 (37%), Gaps = 21/169 (12%) Query: 466 GGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT-SGSSAGELELLAGEVPARSPGA 524 GG P+ G TA+ +E E+ + + R + +GS E +L + A +P Sbjct: 1071 GGPNHPPAPRGRTASET-RSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPK- 1128 Query: 525 FDMSGVRGSLAEA-VGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPG 583 G+L + + PPP A P+P P F + + SR G G Sbjct: 1129 ------EGTLTQVPLAPPPPGAPPSP------APARFTARGGRVFTPRGVPSRRG--RGG 1174 Query: 584 AKASNPFLPGGGPATGPSVTN--PFQPAPPATLTLNQLRLSPVPPVPGA 630 + PG P P P PP+ L + +L P P P A Sbjct: 1175 GRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKE-KLIPGPLSPVA 1222 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 67.4 bits (163), Expect = 4e-11 Identities = 86/331 (25%), Positives = 107/331 (32%), Gaps = 54/331 (16%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPT---AAPTSDPWGGPPVP--PAADPWGGPAPT-PASG 404 T PAPTT P PT +APT+ P P PA PAPT P Sbjct: 266 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325 Query: 405 DPWRPAAPAGPSVDPWGGTP---APAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P P PA + +P TP AP A + P P P+ + P PAP Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---------TTPKEPAPTTPKEPAPTT 376 Query: 462 S-DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 520 + +P +P +P+ T +A EP PT+ SA + Sbjct: 377 TKEPSPTTPKEPAPTTTKSAPTTTKEP------------APTTTKSAPTTPKEPSPTTTK 424 Query: 521 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 580 P + + P P P P T K P P + P PT Sbjct: 425 EPAP---TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPT 477 Query: 581 PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQL--------------RLSPVPP 626 P K + P P T P P P PA T +L +P P Sbjct: 478 TP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 535 Query: 627 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 657 AP T P P P P PAP T Sbjct: 536 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566 Score = 65.9 bits (159), Expect = 1e-10 Identities = 81/325 (24%), Positives = 106/325 (32%), Gaps = 27/325 (8%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T PAPTT AP P T +P P PA PAPT P P Sbjct: 243 TPKEPAPTTTK---SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 299 Query: 411 APAGPSVDPWGGT----PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP-AFSDPW 465 PA + T PAP + PTP + P+ + P PAP A P Sbjct: 300 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPA 357 Query: 466 GGSPAKPS-TNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 524 +P +P+ T A EP + + T ++ ++ E + +P Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417 Query: 525 FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT---- 580 + + P P P P T K P P + +P PT Sbjct: 418 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPAPTTTKKPAPTTPKE 473 Query: 581 --PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLR-LSPVPPVPGAP--PTYI 635 P K + P P T P P P PA T +L +P P P P P Sbjct: 474 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 533 Query: 636 SPLGGGPGL---PPMMPPGPPAPNT 657 +P P P P PAP T Sbjct: 534 TPKAAAPNTPKEPAPTTPKEPAPTT 558 Score = 60.8 bits (146), Expect = 4e-09 Identities = 86/341 (25%), Positives = 113/341 (33%), Gaps = 40/341 (11%) Query: 331 SKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAV---PTAAPTSDPWGGPPV 387 S +ET E++S DLA PT+ P P A P +P P Sbjct: 172 SAKETQSIEKTSAKDLA---------PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK 222 Query: 388 PPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGT---PAPAAGEGP---TPDPWGSSD 441 PA+ P PT P P PA + T PAP + P TP + Sbjct: 223 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 282 Query: 442 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP 501 P + S P TP +P +P KP+ TT T P E + A P Sbjct: 283 TKEPAPTTTKSAPTTP----KEPAPTTPKKPAP--TTPKEPAPTTPKEPTPTTPKEPA-P 335 Query: 502 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFL 561 T+ A + P + + P P T P+P T K P Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 392 Query: 562 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP-----PATLTL 616 +A + P PT + + P P P+ T P +PAP PA T Sbjct: 393 TKSA-----PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447 Query: 617 NQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 657 + +P P AP T P P P P AP T Sbjct: 448 KE--PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 486 Score = 59.7 bits (143), Expect = 8e-09 Identities = 80/316 (25%), Positives = 100/316 (31%), Gaps = 48/316 (15%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T PAPTT PAP P APT+ P P P TP + + P Sbjct: 446 TPKEPAPTTPK--EPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 501 Query: 411 APAGPSVDPWGGTP---APAAGEGPTP----DPWGSSDGGVPVSGPSASDPWTPA-PAFS 462 P P+ TP AP E PTP +P ++ + P P TP PA + Sbjct: 502 TPEKPAPT----TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 557 Query: 463 DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 522 P +P P T G T P L+ PT+ EL + Sbjct: 558 TPKEPAPTTPKETAPTTPKG--TAPTT------LKEPAPTTPKKPAPKELAPTTTKEPTS 609 Query: 523 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 582 D A +P A TP P TP+ + + P PT P Sbjct: 610 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG---------TAPTTLKEPAPTTP 660 Query: 583 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 642 A P GP+ T +PAP P AP T P P Sbjct: 661 KKPAPKELAPT--TTKGPTSTTSDKPAPTT-------------PKETAPTTPKEPAPTTP 705 Query: 643 GLPPMMPPGPPAPNTN 658 P P P P T+ Sbjct: 706 KKPAPTTPETPPPTTS 721 Score = 48.9 bits (115), Expect = 1e-05 Identities = 81/322 (25%), Positives = 108/322 (33%), Gaps = 63/322 (19%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTA----APTSDPWGGPPVPPAADPWGGPAPTPASGDP 406 T PAPTT P PT APT+ P P P PTP + + Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 529 Query: 407 WRPAAP--AGPSV--DPWGGTP---APAAGEGPTPDPWGSSDGGVP-------VSGPSAS 452 P P A P+ +P TP AP + P P + P + P+ + Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 589 Query: 453 DPWTPAP------AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT-SGS 505 P PAP +P + KP+ TT G T P E + A T G+ Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 647 Query: 506 SAGELELLAGEVPAR-SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPN 564 + L+ A P + +P + +G + P P TP T PT TP+ Sbjct: 648 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT-TPKETAPT--TPKE----- 699 Query: 565 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL------TLNQ 618 P PT P K P P P T V+ P P T+ + + Sbjct: 700 ------------PAPTTP--KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 745 Query: 619 LRLSPVPPV-------PGAPPT 633 L P P PG P T Sbjct: 746 LSAEPTPKALENSPKEPGVPTT 767 Score = 46.6 bits (109), Expect = 7e-05 Identities = 67/269 (24%), Positives = 92/269 (34%), Gaps = 25/269 (9%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T P PTT PAP AAP + P P P P P + P Sbjct: 518 TPEEPTPTTPE--EPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 573 Query: 411 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS---------GPSASDPWTP-APA 460 P G + PAP + P P + P S P + P TP PA Sbjct: 574 TPKGTAPTTL-KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 632 Query: 461 FSDPWGGSPAKP-STNGTTAAGGFDTEPDEFSDFDRLRTAL--PTSGSSAGELELLAGEV 517 + P +P P T TT T P + + + T PTS +S E Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 692 Query: 518 PARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESF-LGPNAALVDLDSLVSR 576 +P + + +PPP + TP T K P + P+ + +L + Sbjct: 693 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA---- 748 Query: 577 PGPTPPGAKASNPFLPGGGPATGPSVTNP 605 PTP A ++P PG P+ T P Sbjct: 749 -EPTPK-ALENSPKEPGVPTTKTPAATKP 775 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 67.4 bits (163), Expect = 4e-11 Identities = 86/331 (25%), Positives = 107/331 (32%), Gaps = 54/331 (16%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPT---AAPTSDPWGGPPVP--PAADPWGGPAPT-PASG 404 T PAPTT P PT +APT+ P P PA PAPT P Sbjct: 307 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366 Query: 405 DPWRPAAPAGPSVDPWGGTP---APAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P P PA + +P TP AP A + P P P+ + P PAP Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---------TTPKEPAPTTPKEPAPTT 417 Query: 462 S-DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 520 + +P +P +P+ T +A EP PT+ SA + Sbjct: 418 TKEPSPTTPKEPAPTTTKSAPTTTKEP------------APTTTKSAPTTPKEPSPTTTK 465 Query: 521 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 580 P + + P P P P T K P P + P PT Sbjct: 466 EPAP---TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPT 518 Query: 581 PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQL--------------RLSPVPP 626 P K + P P T P P P PA T +L +P P Sbjct: 519 TP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 576 Query: 627 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 657 AP T P P P P PAP T Sbjct: 577 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607 Score = 65.9 bits (159), Expect = 1e-10 Identities = 81/325 (24%), Positives = 106/325 (32%), Gaps = 27/325 (8%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T PAPTT AP P T +P P PA PAPT P P Sbjct: 284 TPKEPAPTTTK---SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 340 Query: 411 APAGPSVDPWGGT----PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP-AFSDPW 465 PA + T PAP + PTP + P+ + P PAP A P Sbjct: 341 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPA 398 Query: 466 GGSPAKPS-TNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 524 +P +P+ T A EP + + T ++ ++ E + +P Sbjct: 399 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458 Query: 525 FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT---- 580 + + P P P P T K P P + +P PT Sbjct: 459 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPAPTTTKKPAPTTPKE 514 Query: 581 --PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLR-LSPVPPVPGAP--PTYI 635 P K + P P T P P P PA T +L +P P P P P Sbjct: 515 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 574 Query: 636 SPLGGGPGL---PPMMPPGPPAPNT 657 +P P P P PAP T Sbjct: 575 TPKAAAPNTPKEPAPTTPKEPAPTT 599 Score = 60.8 bits (146), Expect = 4e-09 Identities = 86/341 (25%), Positives = 113/341 (33%), Gaps = 40/341 (11%) Query: 331 SKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAV---PTAAPTSDPWGGPPV 387 S +ET E++S DLA PT+ P P A P +P P Sbjct: 213 SAKETQSIEKTSAKDLA---------PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK 263 Query: 388 PPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGT---PAPAAGEGP---TPDPWGSSD 441 PA+ P PT P P PA + T PAP + P TP + Sbjct: 264 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 323 Query: 442 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP 501 P + S P TP +P +P KP+ TT T P E + A P Sbjct: 324 TKEPAPTTTKSAPTTP----KEPAPTTPKKPAP--TTPKEPAPTTPKEPTPTTPKEPA-P 376 Query: 502 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFL 561 T+ A + P + + P P T P+P T K P Sbjct: 377 TTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 433 Query: 562 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP-----PATLTL 616 +A + P PT + + P P P+ T P +PAP PA T Sbjct: 434 TKSA-----PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488 Query: 617 NQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 657 + +P P AP T P P P P AP T Sbjct: 489 KE--PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 527 Score = 59.7 bits (143), Expect = 8e-09 Identities = 80/316 (25%), Positives = 100/316 (31%), Gaps = 48/316 (15%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T PAPTT PAP P APT+ P P P TP + + P Sbjct: 487 TPKEPAPTTPK--EPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 542 Query: 411 APAGPSVDPWGGTP---APAAGEGPTP----DPWGSSDGGVPVSGPSASDPWTPA-PAFS 462 P P+ TP AP E PTP +P ++ + P P TP PA + Sbjct: 543 TPEKPAPT----TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 598 Query: 463 DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 522 P +P P T G T P L+ PT+ EL + Sbjct: 599 TPKEPAPTTPKETAPTTPKG--TAPTT------LKEPAPTTPKKPAPKELAPTTTKEPTS 650 Query: 523 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 582 D A +P A TP P TP+ + + P PT P Sbjct: 651 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG---------TAPTTLKEPAPTTP 701 Query: 583 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 642 A P GP+ T +PAP P AP T P P Sbjct: 702 KKPAPKELAPT--TTKGPTSTTSDKPAPTT-------------PKETAPTTPKEPAPTTP 746 Query: 643 GLPPMMPPGPPAPNTN 658 P P P P T+ Sbjct: 747 KKPAPTTPETPPPTTS 762 Score = 48.9 bits (115), Expect = 1e-05 Identities = 81/322 (25%), Positives = 108/322 (33%), Gaps = 63/322 (19%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTA----APTSDPWGGPPVPPAADPWGGPAPTPASGDP 406 T PAPTT P PT APT+ P P P PTP + + Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 570 Query: 407 WRPAAP--AGPSV--DPWGGTP---APAAGEGPTPDPWGSSDGGVP-------VSGPSAS 452 P P A P+ +P TP AP + P P + P + P+ + Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 630 Query: 453 DPWTPAP------AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT-SGS 505 P PAP +P + KP+ TT G T P E + A T G+ Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 688 Query: 506 SAGELELLAGEVPAR-SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPN 564 + L+ A P + +P + +G + P P TP T PT TP+ Sbjct: 689 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT-TPKETAPT--TPKE----- 740 Query: 565 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL------TLNQ 618 P PT P K P P P T V+ P P T+ + + Sbjct: 741 ------------PAPTTP--KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 786 Query: 619 LRLSPVPPV-------PGAPPT 633 L P P PG P T Sbjct: 787 LSAEPTPKALENSPKEPGVPTT 808 Score = 46.6 bits (109), Expect = 7e-05 Identities = 67/269 (24%), Positives = 92/269 (34%), Gaps = 25/269 (9%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T P PTT PAP AAP + P P P P P + P Sbjct: 559 TPEEPTPTTPE--EPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 614 Query: 411 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS---------GPSASDPWTP-APA 460 P G + PAP + P P + P S P + P TP PA Sbjct: 615 TPKGTAPTTL-KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 673 Query: 461 FSDPWGGSPAKP-STNGTTAAGGFDTEPDEFSDFDRLRTAL--PTSGSSAGELELLAGEV 517 + P +P P T TT T P + + + T PTS +S E Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 733 Query: 518 PARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESF-LGPNAALVDLDSLVSR 576 +P + + +PPP + TP T K P + P+ + +L + Sbjct: 734 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA---- 789 Query: 577 PGPTPPGAKASNPFLPGGGPATGPSVTNP 605 PTP A ++P PG P+ T P Sbjct: 790 -EPTPK-ALENSPKEPGVPTTKTPAATKP 816 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 67.4 bits (163), Expect = 4e-11 Identities = 86/331 (25%), Positives = 107/331 (32%), Gaps = 54/331 (16%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPT---AAPTSDPWGGPPVP--PAADPWGGPAPT-PASG 404 T PAPTT P PT +APT+ P P PA PAPT P Sbjct: 359 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418 Query: 405 DPWRPAAPAGPSVDPWGGTP---APAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P P PA + +P TP AP A + P P P+ + P PAP Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---------TTPKEPAPTTPKEPAPTT 469 Query: 462 S-DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 520 + +P +P +P+ T +A EP PT+ SA + Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKEP------------APTTTKSAPTTPKEPSPTTTK 517 Query: 521 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 580 P + + P P P P T K P P + P PT Sbjct: 518 EPAP---TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPT 570 Query: 581 PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQL--------------RLSPVPP 626 P K + P P T P P P PA T +L +P P Sbjct: 571 TP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 628 Query: 627 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 657 AP T P P P P PAP T Sbjct: 629 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659 Score = 65.9 bits (159), Expect = 1e-10 Identities = 81/325 (24%), Positives = 106/325 (32%), Gaps = 27/325 (8%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T PAPTT AP P T +P P PA PAPT P P Sbjct: 336 TPKEPAPTTTK---SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 392 Query: 411 APAGPSVDPWGGT----PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP-AFSDPW 465 PA + T PAP + PTP + P+ + P PAP A P Sbjct: 393 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPA 450 Query: 466 GGSPAKPS-TNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 524 +P +P+ T A EP + + T ++ ++ E + +P Sbjct: 451 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 510 Query: 525 FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT---- 580 + + P P P P T K P P + +P PT Sbjct: 511 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPAPTTTKKPAPTTPKE 566 Query: 581 --PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLR-LSPVPPVPGAP--PTYI 635 P K + P P T P P P PA T +L +P P P P P Sbjct: 567 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 626 Query: 636 SPLGGGPGL---PPMMPPGPPAPNT 657 +P P P P PAP T Sbjct: 627 TPKAAAPNTPKEPAPTTPKEPAPTT 651 Score = 60.8 bits (146), Expect = 4e-09 Identities = 86/341 (25%), Positives = 113/341 (33%), Gaps = 40/341 (11%) Query: 331 SKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAV---PTAAPTSDPWGGPPV 387 S +ET E++S DLA PT+ P P A P +P P Sbjct: 265 SAKETQSIEKTSAKDLA---------PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK 315 Query: 388 PPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGT---PAPAAGEGP---TPDPWGSSD 441 PA+ P PT P P PA + T PAP + P TP + Sbjct: 316 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 375 Query: 442 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP 501 P + S P TP +P +P KP+ TT T P E + A P Sbjct: 376 TKEPAPTTTKSAPTTP----KEPAPTTPKKPAP--TTPKEPAPTTPKEPTPTTPKEPA-P 428 Query: 502 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFL 561 T+ A + P + + P P T P+P T K P Sbjct: 429 TTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 485 Query: 562 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP-----PATLTL 616 +A + P PT + + P P P+ T P +PAP PA T Sbjct: 486 TKSA-----PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 540 Query: 617 NQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 657 + +P P AP T P P P P AP T Sbjct: 541 KE--PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 579 Score = 59.7 bits (143), Expect = 8e-09 Identities = 80/316 (25%), Positives = 100/316 (31%), Gaps = 48/316 (15%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T PAPTT PAP P APT+ P P P TP + + P Sbjct: 539 TPKEPAPTTPK--EPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 594 Query: 411 APAGPSVDPWGGTP---APAAGEGPTP----DPWGSSDGGVPVSGPSASDPWTPA-PAFS 462 P P+ TP AP E PTP +P ++ + P P TP PA + Sbjct: 595 TPEKPAPT----TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 650 Query: 463 DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 522 P +P P T G T P L+ PT+ EL + Sbjct: 651 TPKEPAPTTPKETAPTTPKG--TAPTT------LKEPAPTTPKKPAPKELAPTTTKEPTS 702 Query: 523 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 582 D A +P A TP P TP+ + + P PT P Sbjct: 703 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG---------TAPTTLKEPAPTTP 753 Query: 583 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 642 A P GP+ T +PAP P AP T P P Sbjct: 754 KKPAPKELAPT--TTKGPTSTTSDKPAPTT-------------PKETAPTTPKEPAPTTP 798 Query: 643 GLPPMMPPGPPAPNTN 658 P P P P T+ Sbjct: 799 KKPAPTTPETPPPTTS 814 Score = 48.9 bits (115), Expect = 1e-05 Identities = 81/322 (25%), Positives = 108/322 (33%), Gaps = 63/322 (19%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTA----APTSDPWGGPPVPPAADPWGGPAPTPASGDP 406 T PAPTT P PT APT+ P P P PTP + + Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 622 Query: 407 WRPAAP--AGPSV--DPWGGTP---APAAGEGPTPDPWGSSDGGVP-------VSGPSAS 452 P P A P+ +P TP AP + P P + P + P+ + Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682 Query: 453 DPWTPAP------AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT-SGS 505 P PAP +P + KP+ TT G T P E + A T G+ Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 740 Query: 506 SAGELELLAGEVPAR-SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPN 564 + L+ A P + +P + +G + P P TP T PT TP+ Sbjct: 741 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT-TPKETAPT--TPKE----- 792 Query: 565 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL------TLNQ 618 P PT P K P P P T V+ P P T+ + + Sbjct: 793 ------------PAPTTP--KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 838 Query: 619 LRLSPVPPV-------PGAPPT 633 L P P PG P T Sbjct: 839 LSAEPTPKALENSPKEPGVPTT 860 Score = 46.6 bits (109), Expect = 7e-05 Identities = 67/269 (24%), Positives = 92/269 (34%), Gaps = 25/269 (9%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T P PTT PAP AAP + P P P P P + P Sbjct: 611 TPEEPTPTTPE--EPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 666 Query: 411 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS---------GPSASDPWTP-APA 460 P G + PAP + P P + P S P + P TP PA Sbjct: 667 TPKGTAPTTL-KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 725 Query: 461 FSDPWGGSPAKP-STNGTTAAGGFDTEPDEFSDFDRLRTAL--PTSGSSAGELELLAGEV 517 + P +P P T TT T P + + + T PTS +S E Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785 Query: 518 PARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESF-LGPNAALVDLDSLVSR 576 +P + + +PPP + TP T K P + P+ + +L + Sbjct: 786 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA---- 841 Query: 577 PGPTPPGAKASNPFLPGGGPATGPSVTNP 605 PTP A ++P PG P+ T P Sbjct: 842 -EPTPK-ALENSPKEPGVPTTKTPAATKP 868 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 67.4 bits (163), Expect = 4e-11 Identities = 86/331 (25%), Positives = 107/331 (32%), Gaps = 54/331 (16%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPT---AAPTSDPWGGPPVP--PAADPWGGPAPT-PASG 404 T PAPTT P PT +APT+ P P PA PAPT P Sbjct: 400 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459 Query: 405 DPWRPAAPAGPSVDPWGGTP---APAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 461 P P PA + +P TP AP A + P P P+ + P PAP Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---------TTPKEPAPTTPKEPAPTT 510 Query: 462 S-DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 520 + +P +P +P+ T +A EP PT+ SA + Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKEP------------APTTTKSAPTTPKEPSPTTTK 558 Query: 521 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 580 P + + P P P P T K P P + P PT Sbjct: 559 EPAP---TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPT 611 Query: 581 PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQL--------------RLSPVPP 626 P K + P P T P P P PA T +L +P P Sbjct: 612 TP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 669 Query: 627 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 657 AP T P P P P PAP T Sbjct: 670 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700 Score = 65.9 bits (159), Expect = 1e-10 Identities = 81/325 (24%), Positives = 106/325 (32%), Gaps = 27/325 (8%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T PAPTT AP P T +P P PA PAPT P P Sbjct: 377 TPKEPAPTTTK---SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 433 Query: 411 APAGPSVDPWGGT----PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP-AFSDPW 465 PA + T PAP + PTP + P+ + P PAP A P Sbjct: 434 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPA 491 Query: 466 GGSPAKPS-TNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 524 +P +P+ T A EP + + T ++ ++ E + +P Sbjct: 492 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 551 Query: 525 FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT---- 580 + + P P P P T K P P + +P PT Sbjct: 552 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPAPTTTKKPAPTTPKE 607 Query: 581 --PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLR-LSPVPPVPGAP--PTYI 635 P K + P P T P P P PA T +L +P P P P P Sbjct: 608 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 667 Query: 636 SPLGGGPGL---PPMMPPGPPAPNT 657 +P P P P PAP T Sbjct: 668 TPKAAAPNTPKEPAPTTPKEPAPTT 692 Score = 60.8 bits (146), Expect = 4e-09 Identities = 86/341 (25%), Positives = 113/341 (33%), Gaps = 40/341 (11%) Query: 331 SKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAV---PTAAPTSDPWGGPPV 387 S +ET E++S DLA PT+ P P A P +P P Sbjct: 306 SAKETQSIEKTSAKDLA---------PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK 356 Query: 388 PPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGT---PAPAAGEGP---TPDPWGSSD 441 PA+ P PT P P PA + T PAP + P TP + Sbjct: 357 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 416 Query: 442 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP 501 P + S P TP +P +P KP+ TT T P E + A P Sbjct: 417 TKEPAPTTTKSAPTTP----KEPAPTTPKKPAP--TTPKEPAPTTPKEPTPTTPKEPA-P 469 Query: 502 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFL 561 T+ A + P + + P P T P+P T K P Sbjct: 470 TTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 526 Query: 562 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP-----PATLTL 616 +A + P PT + + P P P+ T P +PAP PA T Sbjct: 527 TKSA-----PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 581 Query: 617 NQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 657 + +P P AP T P P P P AP T Sbjct: 582 KE--PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 620 Score = 59.7 bits (143), Expect = 8e-09 Identities = 80/316 (25%), Positives = 100/316 (31%), Gaps = 48/316 (15%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T PAPTT PAP P APT+ P P P TP + + P Sbjct: 580 TPKEPAPTTPK--EPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 635 Query: 411 APAGPSVDPWGGTP---APAAGEGPTP----DPWGSSDGGVPVSGPSASDPWTPA-PAFS 462 P P+ TP AP E PTP +P ++ + P P TP PA + Sbjct: 636 TPEKPAPT----TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 691 Query: 463 DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 522 P +P P T G T P L+ PT+ EL + Sbjct: 692 TPKEPAPTTPKETAPTTPKG--TAPTT------LKEPAPTTPKKPAPKELAPTTTKEPTS 743 Query: 523 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 582 D A +P A TP P TP+ + + P PT P Sbjct: 744 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG---------TAPTTLKEPAPTTP 794 Query: 583 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 642 A P GP+ T +PAP P AP T P P Sbjct: 795 KKPAPKELAPT--TTKGPTSTTSDKPAPTT-------------PKETAPTTPKEPAPTTP 839 Query: 643 GLPPMMPPGPPAPNTN 658 P P P P T+ Sbjct: 840 KKPAPTTPETPPPTTS 855 Score = 48.9 bits (115), Expect = 1e-05 Identities = 81/322 (25%), Positives = 108/322 (33%), Gaps = 63/322 (19%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTA----APTSDPWGGPPVPPAADPWGGPAPTPASGDP 406 T PAPTT P PT APT+ P P P PTP + + Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 663 Query: 407 WRPAAP--AGPSV--DPWGGTP---APAAGEGPTPDPWGSSDGGVP-------VSGPSAS 452 P P A P+ +P TP AP + P P + P + P+ + Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723 Query: 453 DPWTPAP------AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT-SGS 505 P PAP +P + KP+ TT G T P E + A T G+ Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 781 Query: 506 SAGELELLAGEVPAR-SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPN 564 + L+ A P + +P + +G + P P TP T PT TP+ Sbjct: 782 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT-TPKETAPT--TPKE----- 833 Query: 565 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL------TLNQ 618 P PT P K P P P T V+ P P T+ + + Sbjct: 834 ------------PAPTTP--KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 879 Query: 619 LRLSPVPPV-------PGAPPT 633 L P P PG P T Sbjct: 880 LSAEPTPKALENSPKEPGVPTT 901 Score = 46.6 bits (109), Expect = 7e-05 Identities = 67/269 (24%), Positives = 92/269 (34%), Gaps = 25/269 (9%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 410 T P PTT PAP AAP + P P P P P + P Sbjct: 652 TPEEPTPTTPE--EPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 707 Query: 411 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS---------GPSASDPWTP-APA 460 P G + PAP + P P + P S P + P TP PA Sbjct: 708 TPKGTAPTTL-KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 766 Query: 461 FSDPWGGSPAKP-STNGTTAAGGFDTEPDEFSDFDRLRTAL--PTSGSSAGELELLAGEV 517 + P +P P T TT T P + + + T PTS +S E Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826 Query: 518 PARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESF-LGPNAALVDLDSLVSR 576 +P + + +PPP + TP T K P + P+ + +L + Sbjct: 827 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA---- 882 Query: 577 PGPTPPGAKASNPFLPGGGPATGPSVTNP 605 PTP A ++P PG P+ T P Sbjct: 883 -EPTPK-ALENSPKEPGVPTTKTPAATKP 909 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 67.4 bits (163), Expect = 4e-11 Identities = 84/308 (27%), Positives = 100/308 (32%), Gaps = 45/308 (14%) Query: 361 PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPW 420 P GG P P P P G P P G P P GD R +P P P Sbjct: 62 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR--SPRSPPGKPQ 119 Query: 421 GGTPAPAAG---EGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGT 477 G P P G +GP P P G G P G P P G P P G Sbjct: 120 G--PPPQGGNQPQGPPPPP-GKPQGPPPQGGNKPQGPPPP---------GKPQGPPPQGD 167 Query: 478 TAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEA 537 + + P + + P G+ + P PG +G Sbjct: 168 NKSRSSRSPPG------KPQGPPPQGGNQP--------QGPPPPPGKPQGPPPQGG--NK 211 Query: 538 VGSPPPAATPTPTPPT--RKTPESFLGPNAALVDLDSLVSRP-GPTPPGAKASNPFLPGG 594 PPP P PP K+ + P ++P GP PP K P GG Sbjct: 212 PQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 271 Query: 595 GPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGG----GPGLPPMMPP 650 GP Q PP + ++ SP P P PP P GG GP PP P Sbjct: 272 NKPQGPPPPGKPQGPPPQGGSKSRSSRSP-PGKPQGPP----PQGGNQPQGPPPPPGKPQ 326 Query: 651 GPPAPNTN 658 GPP N Sbjct: 327 GPPPQGGN 334 Score = 63.2 bits (152), Expect = 8e-10 Identities = 82/318 (25%), Positives = 96/318 (30%), Gaps = 59/318 (18%) Query: 361 PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWR------PAAPAG 414 P GG P P P P G P P G P P GD P P G Sbjct: 123 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182 Query: 415 PSVD----PWGGTPAPAAGEGPTPD----PWGSSDGGVPVSGPSASD------------P 454 P P G P P +GP P P G G P P D P Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP 242 Query: 455 WTPAP-AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELL 513 P P + P G P G GG +P + + P GS + Sbjct: 243 QGPPPQGGNQPQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKPQGPPPQGGSKSRS---- 296 Query: 514 AGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSL 573 +RSP + G PPP P PP G N Sbjct: 297 -----SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ--------GGNKP------- 336 Query: 574 VSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPT 633 GP PPG P P GG + + + P +P P N + P PP G P Sbjct: 337 ---QGPPPPGKPQGPP--PQGGSKSRSARSPPGKPQGPPQQEGNNPQ-GPPPPAGGNPQQ 390 Query: 634 YISPLGGGPGLPPMMPPG 651 +P G P PP P G Sbjct: 391 PQAPPAGQPQGPPRPPQG 408 Score = 60.5 bits (145), Expect = 5e-09 Identities = 73/279 (26%), Positives = 80/279 (28%), Gaps = 50/279 (17%) Query: 388 PPAADPWGGPAPTPASGDPWRPAAPAGPSVD----PWGGTPAPAAGEGPTPDPWGSSDGG 443 P A P GG P G P P P GP P G P P +GP P G Sbjct: 36 PQGAPPQGGNKP---QGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 92 Query: 444 VPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTS 503 P P P G P P G G P + P Sbjct: 93 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-------PQGPPPQ 145 Query: 504 GSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGP 563 G + + G P PG +G PP P P P+ Sbjct: 146 GGNKPQ-----GPPP---PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ----- 192 Query: 564 NAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSP 623 GP PP K P GG GP Q PP +Q SP Sbjct: 193 --------------GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238 Query: 624 VPPVPGAPPTYISPLGG----GPGLPPMMPPGPPAPNTN 658 P P PP P GG GP PP P GPP N Sbjct: 239 -PGKPQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGN 272 Score = 41.2 bits (95), Expect = 0.003 Identities = 42/163 (25%), Positives = 52/163 (31%), Gaps = 24/163 (14%) Query: 330 ESKRETGGKEESSLMDLADVFTAPAPAPTTD----PWGGPAPMAAAVPTAAPTSDPWGG- 384 +S R GK + + P P P P GG P P P GG Sbjct: 233 QSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 292 Query: 385 --------PPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDP 436 P P P GG P P +P P + G P P +GP P Sbjct: 293 KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 352 Query: 437 WGSSDG-----GVPVSGP--SASDPWTPAPAFSDPWGGSPAKP 472 S G P P ++P P P P GG+P +P Sbjct: 353 GSKSRSARSPPGKPQGPPQQEGNNPQGPPP----PAGGNPQQP 391 Score = 39.3 bits (90), Expect = 0.012 Identities = 34/118 (28%), Positives = 38/118 (32%), Gaps = 21/118 (17%) Query: 355 PAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAG 414 P P GP P P P P G P PP P GG A P +P P Sbjct: 318 PPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPP---PQGGSKSRSARSPPGKPQGPPQ 371 Query: 415 PSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKP 472 + G P PA G P P A P P P GG P++P Sbjct: 372 QEGNNPQGPPPPAGGNPQQP------------QAPPAGQPQGPP---RPPQGGRPSRP 414 >gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] Length = 638 Score = 67.0 bits (162), Expect = 5e-11 Identities = 79/286 (27%), Positives = 105/286 (36%), Gaps = 31/286 (10%) Query: 383 GGPPVPPAADPWGGPAPTPASGDPWRPAAPAG----PSVDPWGGTPAPAAGEGPTPD-PW 437 G PVP + GPA TP + P RPAAPA PS+ + P GP+ P+ Sbjct: 321 GEAPVPASVGSTSGPATTPLASAP-RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379 Query: 438 GSSDGGVPVSGPSASDPWT---PAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFD 494 GG P G P + P P+ + GG P + + NG P + Sbjct: 380 HGMHGGGP--GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPW-MQPPPPPMNQGP 436 Query: 495 RLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAAT--PTPTPP 552 P ++ G P S G + + +G + PPP P P PP Sbjct: 437 H-----PPGHHGPPPMDQYLGSTPVGS-GVYRLHQGKGMMP-----PPPMGMMPPPPPPP 485 Query: 553 TRKTPESFLGPNAALVDLDSLVSRPGPTPP--GAKASNPFLPGGGPATGPSVTNPFQPAP 610 + + P GP L +P P PP + AS+ LP T + + P Sbjct: 486 SGQPPPPPSGP---LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIP 542 Query: 611 PATLTLNQLRLSP-VPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 655 P SP P + G P P G P LPP PP PP P Sbjct: 543 PWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPP 588 Score = 45.1 bits (105), Expect = 2e-04 Identities = 92/356 (25%), Positives = 110/356 (30%), Gaps = 108/356 (30%) Query: 338 KEESSLMDLADVFTAPAPAPTTDPWGGPA--PMAAAVPTAAPTSDP-------------- 381 KE SLM A++ AP PA + GPA P+A+A AAP ++P Sbjct: 311 KEYLSLM--AELGEAPVPA-SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPP 367 Query: 382 W---------------GGPPVPPAADPWGGPAPTPA-----SGDPWRPAAPAGPSVDPWG 421 W GG P P P P P P+ G P + P GP PW Sbjct: 368 WMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQ-HNPNGPP-PPWM 425 Query: 422 GTPAPAAGEGP------TPDPWGSSDGGVPV----------SGPSASDPWTPAPAFSDPW 465 P P +GP P P G PV G P P P Sbjct: 426 QPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP 485 Query: 466 GGSPAKPSTNGTTAAGGFDTE---PDEFSDFDRLRTALP------TSGSSAGELELLAGE 516 G P P + + P S T LP T+ +SAG G Sbjct: 486 SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAG-----TGS 540 Query: 517 VP---------ARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAAL 567 +P A SPGA M G + G PP P PP Sbjct: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP--------------- 585 Query: 568 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSP 623 P PP A P GG GPS + P P TL Q + P Sbjct: 586 -----------PPPPPGSAGMMIPPRGG--DGPSHESEDFPRPLVTLPGRQPQQRP 628 Score = 32.7 bits (73), Expect = 1.1 Identities = 31/98 (31%), Positives = 36/98 (36%), Gaps = 12/98 (12%) Query: 351 TAPAPAPTTDPWGGPAPMAAAVPTAA-----PTS---DPWGGPPVPPAADPWGGPAPTPA 402 T A + PW AAA P A PT P PP+PP A P P P + Sbjct: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGS 592 Query: 403 SGDPWRPAAPAGPSVDPWGGTPAPAA---GEGPTPDPW 437 +G P GPS + P P G P PW Sbjct: 593 AGMMIPPRGGDGPSHES-EDFPRPLVTLPGRQPQQRPW 629 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.131 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,795,620 Number of Sequences: 37866 Number of extensions: 2745038 Number of successful extensions: 36259 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 457 Number of HSP's successfully gapped in prelim test: 1866 Number of HSP's that attempted gapping in prelim test: 14652 Number of HSP's gapped (non-prelim): 12456 length of query: 662 length of database: 18,247,518 effective HSP length: 109 effective length of query: 553 effective length of database: 14,120,124 effective search space: 7808428572 effective search space used: 7808428572 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.