Guide to the Human Genome
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Name: PLEKHG4 Sequence: fasta or formatted (1191aa) NCBI GI: 193211594
Description:

pleckstrin homology domain containing, family G (with RhoGef domain) member 4 isoform 1

Referenced in:

Inositol Pathways
Additional Serine / Threonine Protein Kinases

Other entries for this name:
alt mRNA [1191aa] pleckstrin homology domain containing, family G (with RhoGef doma...
alt mRNA [1191aa] pleckstrin homology domain containing, family G (with RhoGef doma...
alt prot [1110aa] pleckstrin homology domain containing, family G (with RhoGef doma...
alt mRNA [1191aa] pleckstrin homology domain containing, family G (with RhoGef doma...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.1        120           2
 C cysteine            2.5         30           2
 D aspartate           4.7         56           1
 E glutamate           7.4         88           4
 F phenylalanine       2.9         35           2
 G glycine             7.2         86           3
 H histidine           2.5         30           2
 I isoleucine          1.7         20           1
 K lysine              2.5         30           1
 L leucine            14.3        170           3
 M methionine          1.7         20           1
 N asparagine          1.5         18           1
 P proline             7.1         85           3
 Q glutamine           7.0         83           2
 R arginine            6.7         80           3
 S serine              8.2         98           3
 T threonine           3.3         39           1
 V valine              5.2         62           2
 W tryptophan          1.7         20           1
 Y tyrosine            1.8         21           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   pleckstrin homology domain containing, family G (wi... 
PLEKHG4               1.000   pleckstrin homology domain containing, family G (wi...
PLEKHG4               1.000   pleckstrin homology domain containing, family G (wi...
PLEKHG4               1.000   pleckstrin homology domain containing, family G (wit...
PLEKHG4               0.849   pleckstrin homology domain containing, family G (wi...
PLEKHG4B              0.169   pleckstrin homology domain containing, family G (wi...
FLJ10357              0.158   hypothetical protein LOC55701 
TRIO                  0.071   triple functional domain (PTPRF interacting) 
MCF2L                 0.069   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.069   MCF.2 cell line derived transforming sequence-like ...
KIAA1755              0.068   hypothetical protein LOC85449 
KALRN                 0.066   kalirin, RhoGEF kinase isoform 1 
KALRN                 0.066   kalirin, RhoGEF kinase isoform 3 
KALRN                 0.064   kalirin, RhoGEF kinase isoform 2 
MCF2                  0.064   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.064   MCF.2 cell line derived transforming sequence isofo...
GEFT                  0.063   RhoA/RAC/CDC42 exchange factor isoform 1 
GEFT                  0.063   RhoA/RAC/CDC42 exchange factor isoform 3 
MCF2L2                0.043   Rho family guanine-nucleotide exchange factor 
PLEKHG1               0.042   pleckstrin homology domain containing, family G (wit...
OBSCN                 0.037   obscurin, cytoskeletal calmodulin and titin-interact...
OBSCN                 0.037   obscurin, cytoskeletal calmodulin and titin-interac...
PLEKHG3               0.023   pleckstrin homology domain containing, family G, mem...
PLEKHG2               0.022   common-site lymphoma/leukemia guanine nucleotide ex...
PREX1                 0.021   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
FGD4                  0.018   FYVE, RhoGEF and PH domain containing 4 
DNMBP                 0.018   dynamin binding protein 
FGD2                  0.015   FYVE, RhoGEF and PH domain containing 2 
VAV1                  0.015   vav 1 guanine nucleotide exchange factor 
TIAM1                 0.015   T-cell lymphoma invasion and metastasis 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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