BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens] (875 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens] 1816 0.0 gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens] 1811 0.0 gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens] 1800 0.0 gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens] 1795 0.0 gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 81 4e-15 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 68 3e-11 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 66 1e-10 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 65 4e-10 gi|210032580 SET domain containing 1B [Homo sapiens] 64 6e-10 gi|221219020 NYD-SP11 protein [Homo sapiens] 62 2e-09 gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 62 3e-09 gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 61 4e-09 gi|55741677 SET domain containing 1A [Homo sapiens] 59 2e-08 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 59 3e-08 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 59 3e-08 gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 59 3e-08 gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 59 3e-08 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 57 6e-08 gi|4557509 cylicin 2 [Homo sapiens] 57 6e-08 gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 57 6e-08 gi|156104891 general transcription factor IIF, polypeptide 1, 74... 57 7e-08 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 57 1e-07 gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 56 1e-07 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 56 2e-07 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 56 2e-07 gi|55956788 nucleolin [Homo sapiens] 55 2e-07 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 55 2e-07 gi|83921609 hypothetical protein LOC127254 [Homo sapiens] 55 3e-07 gi|168229156 NFKB activating protein [Homo sapiens] 55 4e-07 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 55 4e-07 >gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens] Length = 875 Score = 1816 bits (4704), Expect = 0.0 Identities = 875/875 (100%), Positives = 875/875 (100%) Query: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR Sbjct: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60 Query: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV Sbjct: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120 Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180 Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240 Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300 Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360 Query: 361 SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTC 420 SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTC Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTC 420 Query: 421 SLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWN 480 SLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWN Sbjct: 421 SLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWN 480 Query: 481 LQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASE 540 LQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASE Sbjct: 481 LQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASE 540 Query: 541 PGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVER 600 PGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVER Sbjct: 541 PGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVER 600 Query: 601 DEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLE 660 DEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLE Sbjct: 601 DEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLE 660 Query: 661 WQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKK 720 WQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKK Sbjct: 661 WQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKK 720 Query: 721 FKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPGL 780 FKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPGL Sbjct: 721 FKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPGL 780 Query: 781 TPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRG 840 TPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRG Sbjct: 781 TPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRG 840 Query: 841 QGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 875 QGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF Sbjct: 841 QGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 875 >gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens] Length = 876 Score = 1811 bits (4692), Expect = 0.0 Identities = 875/876 (99%), Positives = 875/876 (99%), Gaps = 1/876 (0%) Query: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR Sbjct: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60 Query: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV Sbjct: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120 Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180 Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240 Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300 Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360 Query: 361 SFDEGSVSESESESESGQAEEEKEEAE-ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 419 SFDEGSVSESESESESGQAEEEKEEAE ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420 Query: 420 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 479 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW Sbjct: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480 Query: 480 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 539 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS Sbjct: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540 Query: 540 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 599 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE Sbjct: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600 Query: 600 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 659 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL Sbjct: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660 Query: 660 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 719 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK Sbjct: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720 Query: 720 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG 779 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG Sbjct: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG 780 Query: 780 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 839 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR Sbjct: 781 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 840 Query: 840 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 875 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF Sbjct: 841 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 876 >gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens] Length = 871 Score = 1800 bits (4661), Expect = 0.0 Identities = 870/875 (99%), Positives = 870/875 (99%), Gaps = 4/875 (0%) Query: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR Sbjct: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60 Query: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV Sbjct: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120 Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180 Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240 Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300 Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360 Query: 361 SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTC 420 SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTC Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTC 420 Query: 421 SLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWN 480 SLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWN Sbjct: 421 SLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWN 480 Query: 481 LQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASE 540 LQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASE Sbjct: 481 LQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASE 540 Query: 541 PGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVER 600 PGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVER Sbjct: 541 PGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVER 600 Query: 601 DEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLE 660 DEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLE Sbjct: 601 DEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLE 660 Query: 661 WQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKK 720 WQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKK Sbjct: 661 WQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKK 720 Query: 721 FKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPGL 780 FKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ L Sbjct: 721 FKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ----SL 776 Query: 781 TPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRG 840 TPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRG Sbjct: 777 TPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRG 836 Query: 841 QGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 875 QGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF Sbjct: 837 QGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 871 >gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens] Length = 872 Score = 1795 bits (4649), Expect = 0.0 Identities = 870/876 (99%), Positives = 870/876 (99%), Gaps = 5/876 (0%) Query: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR Sbjct: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60 Query: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV Sbjct: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120 Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180 Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240 Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300 Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360 Query: 361 SFDEGSVSESESESESGQAEEEKEEAE-ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 419 SFDEGSVSESESESESGQAEEEKEEAE ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420 Query: 420 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 479 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW Sbjct: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480 Query: 480 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 539 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS Sbjct: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540 Query: 540 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 599 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE Sbjct: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600 Query: 600 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 659 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL Sbjct: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660 Query: 660 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 719 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK Sbjct: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720 Query: 720 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG 779 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ Sbjct: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ----S 776 Query: 780 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 839 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR Sbjct: 777 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 836 Query: 840 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 875 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF Sbjct: 837 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 872 >gi|13540523 nucleosomal binding protein 1 [Homo sapiens] Length = 282 Score = 81.3 bits (199), Expect = 4e-15 Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 8/141 (5%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDE---KKEDGKQAENDSSN-DDK 324 ++E+EE+Q + GE K+++ G G ++ N+K E +KEDGK+ E+ N +D Sbjct: 130 QKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDG 189 Query: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE 384 +K E + ++E++KE + + + K++ K G D V E E E E G+ +E Sbjct: 190 KEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDV----KVKEDEKEREDGKEDEGGN 245 Query: 385 EAEALKEKEKPKEEEWEKPKD 405 E EA KEKE KEEE K +D Sbjct: 246 EEEAGKEKEDLKEEEEGKEED 266 Score = 59.3 bits (142), Expect = 2e-08 Identities = 39/152 (25%), Positives = 78/152 (51%), Gaps = 22/152 (14%) Query: 256 KMEGGTEN-DLRILEQEEEEEQAGKPGEPSKKEE----GRAGAGLGDGERKTNDKDEKKE 310 K E G E+ D + E +E++ + GE +K++E G G G G+ ++ + ++++E Sbjct: 141 KGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEE 200 Query: 311 DGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSES 370 D K+ + N+D +K + K+ K ++ EKE ++G E Sbjct: 201 DRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKER-----------------EDGKEDEG 243 Query: 371 ESESESGQAEEEKEEAEALKEKEKPKEEEWEK 402 +E E+G+ +E+ +E E KE+++ KE++ +K Sbjct: 244 GNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 6/102 (5%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEK-KEDGKQAE 316 +G E+ E E+EEE + G+ + E+G+ +G+ +DEK +EDGK E Sbjct: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGK--E 240 Query: 317 NDSSNDDKTKKSEGD-GDKEEKKEDSEKEAKKSSKKRNRKHS 357 ++ N+++ K + D ++EE KE E E K+ K+ S Sbjct: 241 DEGGNEEEAGKEKEDLKEEEEGKE--EDEIKEDDGKKEEPQS 280 Score = 38.5 bits (88), Expect = 0.027 Identities = 32/148 (21%), Positives = 58/148 (39%), Gaps = 4/148 (2%) Query: 267 ILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326 + E ++E E +K E + + K+E ED + + + Sbjct: 63 VAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAE 122 Query: 327 KSEGDGDKEEKKEDSEK---EAKKSSKKRNRKHSGDDSFDEGSVSESESESESG-QAEEE 382 + D++E +ED + EA K K + G + + E E E G + E+ Sbjct: 123 VKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDG 182 Query: 383 KEEAEALKEKEKPKEEEWEKPKDAAGLE 410 K E KEK + ++EE ++ + G E Sbjct: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKE 210 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 68.2 bits (165), Expect = 3e-11 Identities = 40/134 (29%), Positives = 69/134 (51%), Gaps = 5/134 (3%) Query: 270 QEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE 329 +EEE E + GE +EEG G G +GE + +E++ +G + E + + + ++ E Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG-EGEEEGEGEGEEEEGE 901 Query: 330 GDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVS----ESESESESGQAEEEKEE 385 G+G++E + E E+E + ++ + G+ +EG E E E E G+ E E+EE Sbjct: 902 GEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961 Query: 386 AEALKEKEKPKEEE 399 E E+E E E Sbjct: 962 GEGEGEEEGEGEGE 975 Score = 67.4 bits (163), Expect = 6e-11 Identities = 42/140 (30%), Positives = 75/140 (53%), Gaps = 7/140 (5%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE---DGKQAENDSSNDDKT 325 EQE++E + G E +++ E G+GE + D++E++E +GK+ + + Sbjct: 709 EQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGER 768 Query: 326 KKSEGDGDKEE---KKEDSEKEAKK-SSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381 +K EG+ KEE K+E E+E + ++ + G++ + G V E E G+ EE Sbjct: 769 EKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREE 828 Query: 382 EKEEAEALKEKEKPKEEEWE 401 E+EE E +E+ + +EEE E Sbjct: 829 EEEEGEGEEEEGEGEEEEGE 848 Score = 67.4 bits (163), Expect = 6e-11 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 11/155 (7%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE------- 310 EG E + E E EEE+ GE + EG G G+GE + + E++E Sbjct: 864 EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE 923 Query: 311 DGKQAENDSSNDD---KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSV 367 +G++ E + ++ + + EG+G++EE + + E+E + + + G++ EG Sbjct: 924 EGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEE 983 Query: 368 SESESESESGQAEEE-KEEAEALKEKEKPKEEEWE 401 E E E E + EEE +EE E +E E EEE E Sbjct: 984 EEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018 Score = 67.0 bits (162), Expect = 7e-11 Identities = 42/143 (29%), Positives = 68/143 (47%), Gaps = 10/143 (6%) Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315 K EGG E E E + GK ++EEG G+GE + + +E++ +GK Sbjct: 808 KEEGG--------EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGE 859 Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375 E + + + EG+G+ EE E+ E E ++ + + G+ +E E E E Sbjct: 860 EEGEEGEGEEEGEEGEGEGEE--EEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917 Query: 376 SGQAEEEKEEAEALKEKEKPKEE 398 G+ EEE EE E E+E+ + E Sbjct: 918 EGKGEEEGEEGEGEGEEEEGEGE 940 Score = 67.0 bits (162), Expect = 7e-11 Identities = 45/156 (28%), Positives = 78/156 (50%), Gaps = 12/156 (7%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTND---KDEKKEDGKQ 314 EG E + E EEE E+ GE + E G G+GE + + ++E + +G++ Sbjct: 855 EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEE 914 Query: 315 AENDSSNDDKTKKSEGDGDKEE--------KKEDSEKEAKKSSKKRNRKHSGDDSFD-EG 365 E + +++ ++ EG+G++EE + E E+E + ++ + G++ + EG Sbjct: 915 EEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG 974 Query: 366 SVSESESESESGQAEEEKEEAEALKEKEKPKEEEWE 401 E E E E G+ E E+EE E E+E EEE E Sbjct: 975 EEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGE 1010 Score = 65.9 bits (159), Expect = 2e-10 Identities = 42/156 (26%), Positives = 78/156 (50%), Gaps = 2/156 (1%) Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315 +ME G E + E+EE + + + E KEEG G+ E++ ++ +++ GK+ Sbjct: 726 EMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEE 785 Query: 316 ENDSSNDD-KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES 374 + + D + ++ E +G EEK+E E E + + + + ++ EG E E E Sbjct: 786 KGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEE-GEGEEEEGEGEE 844 Query: 375 ESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLE 410 E G+ EEE+ E + +E E+ + EE + + G E Sbjct: 845 EEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEE 880 Score = 65.5 bits (158), Expect = 2e-10 Identities = 43/148 (29%), Positives = 73/148 (49%), Gaps = 5/148 (3%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGE--PSKKEEGRAGAGLGDG-ERKTNDKDEKKEDGKQ 314 EG E + +E E E+E+ + E K+E+G G+G E +T + E+KE+G + Sbjct: 754 EGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813 Query: 315 AENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES 374 E + K ++ E + + E ++E+ E E ++ + + +EG E E E Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGE--EEGEEGEGEEEG 871 Query: 375 ESGQAEEEKEEAEALKEKEKPKEEEWEK 402 E G+ E E+EE E E+E E E E+ Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEE 899 Score = 65.1 bits (157), Expect = 3e-10 Identities = 43/159 (27%), Positives = 78/159 (49%), Gaps = 9/159 (5%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDG----- 312 EG E + + EEEE GK E ++ EG G+GE + + + ++E+G Sbjct: 899 EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGE 958 Query: 313 -KQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESE 371 ++ E + + + + EG+G+ EE++ + E E ++ ++ + G+ +EG E Sbjct: 959 EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGE---EEGEGEGEE 1015 Query: 372 SESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLE 410 E + E E EE E E+E+ +EE E+ K+ G E Sbjct: 1016 EEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEE 1054 Score = 64.3 bits (155), Expect = 5e-10 Identities = 50/174 (28%), Positives = 81/174 (46%), Gaps = 16/174 (9%) Query: 255 IKMEGGTENDLRILEQE---EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDE-KKE 310 +K+ GG + IL + + E GK + E+G G G G E ++ + + E Sbjct: 613 VKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDE 672 Query: 311 DGKQAENDSSNDDKTKKSEGD---GDKEE-KKEDSEKEAKKSSKKRNRKHSGDDSFDEGS 366 + ++ E D + + EG+ +KEE KK D E++ +K ++ ++K + + G Sbjct: 673 EREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE 732 Query: 367 VSESESESESGQAEEE-------KEEAEALK-EKEKPKEEEWEKPKDAAGLECK 412 E E E G EEE KEE E + E E+ KEE K ++ AG E K Sbjct: 733 EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEK 786 Score = 63.9 bits (154), Expect = 6e-10 Identities = 39/160 (24%), Positives = 81/160 (50%), Gaps = 17/160 (10%) Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA---GAGLGDGERKTNDKDEKKEDG 312 +ME E + + E+EE +++ G+ E ++E+G + +G + + + E++E Sbjct: 685 EMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGD 744 Query: 313 KQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES 372 ++ E + + K EG+G++ E + + E+ +K ++ ++ G++ D+G E E+ Sbjct: 745 REEEEEKEGEGK---EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEET 801 Query: 373 ES-----------ESGQAEEEKEEAEALKEKEKPKEEEWE 401 E E G+ EE K E E +E+ + +EEE E Sbjct: 802 EGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGE 841 Score = 62.8 bits (151), Expect = 1e-09 Identities = 38/134 (28%), Positives = 72/134 (53%), Gaps = 12/134 (8%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGD-GERKTNDKDEKKEDGK-----QAENDSSND 322 E EEE E G+ GE +EE G G + GE + ++ E +E+G+ + E + + Sbjct: 965 EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGE 1024 Query: 323 DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE 382 + ++ EG+G++EE +E+ E+ K+ + NR++ ++ +EG E+G+ E E Sbjct: 1025 VEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKY------QETGEEENE 1078 Query: 383 KEEAEALKEKEKPK 396 +++ E K+ K K Sbjct: 1079 RQDGEEYKKVSKIK 1092 Score = 62.4 bits (150), Expect = 2e-09 Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 19/164 (11%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSK-KEEGRAGAGLGD-----GERKTNDKDEKKED 311 EG E + E+EE E + + GE + +EEG G G G+ GE + + E +E+ Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE 898 Query: 312 GKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKK------------SSKKRNRKHSGD 359 + E + + + ++ EG+G EE+ E+ E E ++ ++ + G+ Sbjct: 899 EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGE 958 Query: 360 DSFDEG-SVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEK 402 + EG E E E E G+ E E+EE E E+E+ +EE E+ Sbjct: 959 EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002 Score = 62.0 bits (149), Expect = 2e-09 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 10/143 (6%) Query: 270 QEEEEEQAGKPGEPSKKEEGRAGAGLGDGER------KTNDKDEKKEDGKQAENDSSNDD 323 +EE EE G+ E + EG G G G+ E + + E +E+G+ + + Sbjct: 922 EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEG 981 Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVS----ESESESESGQA 379 + ++ EG+G++EE +E+ E+E + + ++ EG V E E E E G+ Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE 1041 Query: 380 EEEKEEAEALKEKEKPKEEEWEK 402 E E+ E E E+ + EE E+ Sbjct: 1042 EGEEREKEGEGEENRRNREEEEE 1064 Score = 60.5 bits (145), Expect = 7e-09 Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 5/239 (2%) Query: 165 ETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVF 224 E E ++ K D Q+ ++ H+ E + +E +E G + Sbjct: 693 EKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752 Query: 225 LSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPS 284 E G + + + +K + K + A + +G E D E+EE E + + E Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGG 812 Query: 285 KKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSE-K 343 + E G G G+ E + + + ++E+G+ E + +++ EG+G EE+ E+ E + Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEE----EGEGKGEEEGEEGEGE 868 Query: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEK 402 E + + + G+ +E E E E G+ EEE E +E E EEE E+ Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE 927 Score = 60.5 bits (145), Expect = 7e-09 Identities = 40/141 (28%), Positives = 71/141 (50%), Gaps = 9/141 (6%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317 EG E + E EEEE + GE ++ EG G G+GE + + + ++E+G++ Sbjct: 945 EGEGEEEEGEWEGEEEEGE----GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE 1000 Query: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377 + ++ EG+G+ EE+ E+ E E + ++ + ++ +EG E E E E Sbjct: 1001 EEGEGEE----EGEGEGEEE-EEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055 Query: 378 QAEEEKEEAEALKEKEKPKEE 398 + E+EE E K +E +EE Sbjct: 1056 RRNREEEEEEEGKYQETGEEE 1076 Score = 58.9 bits (141), Expect = 2e-08 Identities = 36/139 (25%), Positives = 71/139 (51%), Gaps = 6/139 (4%) Query: 270 QEEEEEQAGKPGEPSKKEE-----GRAGAGLGDGERKTNDKDEKKE-DGKQAENDSSNDD 323 +EEE E G+ GE +EE G G G+GE + + E+ E +G++ E + ++ Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992 Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383 + + EG+ + E ++E + ++ + + G++ EG E E E E + E E Sbjct: 993 EEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEG 1052 Query: 384 EEAEALKEKEKPKEEEWEK 402 EE +E+E+ +E ++++ Sbjct: 1053 EENRRNREEEEEEEGKYQE 1071 Score = 57.4 bits (137), Expect = 6e-08 Identities = 43/184 (23%), Positives = 88/184 (47%), Gaps = 20/184 (10%) Query: 242 KADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGL-GDGER 300 KA ++ + D + +G E E ++EE+ E +K++GR G+GE+ Sbjct: 640 KAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEER-----EKGEKDKGRGEMERPGEGEK 694 Query: 301 KTNDKDE------------KKEDGKQAENDSSNDDKTKKSEGDGDKEE--KKEDSEKEAK 346 + +K+E ++E G Q E + ++ ++ G+G++EE ++E+ EKE + Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754 Query: 347 KSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDA 406 + + G+ +EG + E + + EEE ++ E +E+ + + EE E+ + Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814 Query: 407 AGLE 410 G E Sbjct: 815 EGGE 818 Score = 52.8 bits (125), Expect = 1e-06 Identities = 32/135 (23%), Positives = 68/135 (50%), Gaps = 8/135 (5%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK-- 326 E EEEEE GE + EG G G G+ E + +E++++G+ EN + +++ + Sbjct: 1012 EGEEEEE-----GEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066 Query: 327 -KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385 K + G++E +++D E+ K S K + K+ ++ + SV+ ++ + +++ + Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQS 1126 Query: 386 AEALKEKEKPKEEEW 400 LK ++ W Sbjct: 1127 KRLLKNGPSGSKKFW 1141 Score = 47.4 bits (111), Expect = 6e-05 Identities = 42/139 (30%), Positives = 68/139 (48%), Gaps = 17/139 (12%) Query: 283 PSKKE--EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKED 340 P +KE E G G+ + E + N+++ K G++ + + +DD T K+E E K Sbjct: 587 PEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAE----VSEGKAK 642 Query: 341 SEKEAKKSSKKRNRKHSGDDSFDEGSVSE---SESESESGQAEEEKEEAE--ALKEKEKP 395 S EA+ + R GD + +EGS + E E G+ ++ + E E EKE Sbjct: 643 SVGEAEDGPEGR-----GDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELA 697 Query: 396 KEEEWEKPKDAAGLECKPR 414 ++EEW+K +D E K R Sbjct: 698 EKEEWKK-RDGEEQEQKER 715 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 66.2 bits (160), Expect = 1e-10 Identities = 48/152 (31%), Positives = 73/152 (48%), Gaps = 14/152 (9%) Query: 259 GGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAG-----LGDGERKTNDKDEKKEDGK 313 GG E+ + E E E G+ GE + + E +G G+GE +T K E+ ED Sbjct: 742 GGQED---VAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDEN 798 Query: 314 QAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSS------KKRNRKHSGDDSFDEGSV 367 +AE N+ + + D E K + E E+++ S K + K D +G Sbjct: 799 EAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGD 858 Query: 368 SESESESESGQAEEEKEEAEALKEKEKPKEEE 399 SE E E E Q EEE+EE + +E+E+ +EEE Sbjct: 859 SEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEE 890 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 64.7 bits (156), Expect = 4e-10 Identities = 34/108 (31%), Positives = 60/108 (55%), Gaps = 2/108 (1%) Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358 +++T + +E +E ++ E + +K K+ + +K++K +++EK +K +++ RK Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66 Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEALKEKEK--PKEEEWEKPK 404 +E E E E E + EEEKEE K+K+K KEEE EK K Sbjct: 67 KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 Score = 47.4 bits (111), Expect = 6e-05 Identities = 24/93 (25%), Positives = 51/93 (54%), Gaps = 1/93 (1%) Query: 313 KQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES 372 K+ + ++T+++E + ++EE+KE KE +K +K K ++ E E Sbjct: 1 KKKKKKKKETEETEETE-ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 Query: 373 ESESGQAEEEKEEAEALKEKEKPKEEEWEKPKD 405 + + +++KEE E +E+E+ +EE+ E+ K+ Sbjct: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92 Score = 34.3 bits (77), Expect = 0.52 Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 4/70 (5%) Query: 350 KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKE-EEWEKPKDAAG 408 KK+ +K + +E +E E E E + E+ KE+ KEKEK K+ +E EK K+ Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKR---KEKEKKKKTKETEKRKEKEE 57 Query: 409 LECKPRPLHK 418 E K + K Sbjct: 58 EEKKRKRKRK 67 Score = 31.2 bits (69), Expect = 4.4 Identities = 14/66 (21%), Positives = 33/66 (50%) Query: 17 RRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPP 76 R+E+ + ++ R+R +++ ++ E + E E ++ R R+++ R E Sbjct: 52 RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 Query: 77 QKRMRR 82 +K+ RR Sbjct: 112 KKKKRR 117 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 63.9 bits (154), Expect = 6e-10 Identities = 44/155 (28%), Positives = 79/155 (50%), Gaps = 15/155 (9%) Query: 259 GGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEND 318 GG E++ L +E+E + + E ++EE D + ++D+DE + D + D Sbjct: 1032 GGEEDEKESLSEEQESTEEEEEAEEEEEEED-------DDDDDSDDRDESEND----DED 1080 Query: 319 SSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE--S 376 ++ + ++K EGD D+EE +A+ +S + + S +S E S S SE E E + Sbjct: 1081 TALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVA 1140 Query: 377 GQAEEEKEEAEALKEKEKPK--EEEWEKPKDAAGL 409 + EEE+EE E + E+ E++E+ + A L Sbjct: 1141 REEEEEEEEEEMVAEESMASAGPEDFEQDGEEAAL 1175 Score = 48.5 bits (114), Expect = 3e-05 Identities = 34/156 (21%), Positives = 69/156 (44%), Gaps = 25/156 (16%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLG-------DGERKTNDKDEKKEDGKQAENDSSN 321 E+E + + A P E +K++ G D + ++K+ E+ + E + Sbjct: 995 ERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEA 1054 Query: 322 DDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSV-------------- 367 +++ ++ + D D + +++SE + + ++ + DS +E +V Sbjct: 1055 EEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSE 1114 Query: 368 ----SESESESESGQAEEEKEEAEALKEKEKPKEEE 399 SE ES SES + E EE +E+E+ +EEE Sbjct: 1115 SSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEE 1150 Score = 38.5 bits (88), Expect = 0.027 Identities = 36/125 (28%), Positives = 57/125 (45%), Gaps = 14/125 (11%) Query: 289 GRAGAGLGDGERKT----NDKDEKKE--------DGKQAENDSSNDDKTKKSEGDGDKEE 336 G G GLG G R + K ++KE D K+ +S D++ ++SE + D++ Sbjct: 943 GYEGLGLGIGLRGAIRLPSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDM 1002 Query: 337 KKEDSE--KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEK 394 E K K R R + G E ES SE ++ EE+EEAE +E+E Sbjct: 1003 ADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEED 1062 Query: 395 PKEEE 399 +++ Sbjct: 1063 DDDDD 1067 Score = 33.9 bits (76), Expect = 0.68 Identities = 23/68 (33%), Positives = 27/68 (39%), Gaps = 5/68 (7%) Query: 759 PALPEIKPAQPPGPAQILPPG--LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAV 816 P P + P PP P Q PG + P LP P P P PP L G P + Sbjct: 685 PGFPPLPPPPPPPPPQ---PGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPI 741 Query: 817 PTGGPPYP 824 PP+P Sbjct: 742 LPPLPPFP 749 Score = 32.7 bits (73), Expect = 1.5 Identities = 24/69 (34%), Positives = 24/69 (34%), Gaps = 16/69 (23%) Query: 759 PALPEIKPAQPPGPAQILPPGLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPT 818 P P P PP P PP PG P P P P P PP PAV Sbjct: 682 PPPPGFPPLPPPPP----PPPPQPGFPMPPPLP----PPPPPPPP--------AHPAVTV 725 Query: 819 GGPPYPHAP 827 PP P P Sbjct: 726 PPPPLPAPP 734 Score = 31.2 bits (69), Expect = 4.4 Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 9/81 (11%) Query: 753 LTDAKRPALPEIKPAQP------PGPAQILPPG-LTPGLPYPHQTPQGLMPYGQPRPPIL 805 ++D + P+ P P PG A + P L P LP P P G P P PP Sbjct: 641 ISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLP--PPPGFPPLPPPPPPPP 698 Query: 806 GYGAGAVRPAVPTGGPPYPHA 826 + P +P PP P A Sbjct: 699 PQPGFPMPPPLPPPPPPPPPA 719 Score = 30.4 bits (67), Expect = 7.5 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 11/81 (13%) Query: 755 DAKRPALPEIKPAQP----PGPAQILPPGLTPGLPYPHQTPQGLMPYGQPRPPILGYGAG 810 +A+ P PE P P P +LP L P LP P P P PP Sbjct: 1249 EARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPR-------PPRPPSPPPEPETTD 1301 Query: 811 AVRPAVPTGGPPYPHAPYGAG 831 A P+VP H P+ G Sbjct: 1302 ASHPSVPPEPLAEDHPPHTPG 1322 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 62.0 bits (149), Expect = 2e-09 Identities = 32/104 (30%), Positives = 65/104 (62%), Gaps = 1/104 (0%) Query: 302 TNDKDEKKEDGKQAENDSSNDDKTKKSEGDGD-KEEKKEDSEKEAKKSSKKRNRKHSGDD 360 + +++E++E+ ++ E + +++ +K E +G+ K+ +KE+ EK+ KK KK+ ++ Sbjct: 2245 SEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE 2304 Query: 361 SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPK 404 F+E SE E+ES EEE+EE+ +L+E+ ++E +K K Sbjct: 2305 VFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348 Score = 47.8 bits (112), Expect = 5e-05 Identities = 40/149 (26%), Positives = 74/149 (49%), Gaps = 10/149 (6%) Query: 267 ILEQEEE---EEQAGKPGEPSK-KEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSND 322 IL+ EEE EE+ P + ++ A G E+ ++ DE + + +E S Sbjct: 2175 ILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLL 2234 Query: 323 DKTKK-----SEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377 D+ +K SE + ++EE++E E+E ++ ++R + G++ E E + + + Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294 Query: 378 QAEEEKEEAEALKEKEK-PKEEEWEKPKD 405 + EE +E+ E +EKE+ EEE E D Sbjct: 2295 KKEEVQEKEEVFEEKEEIMSEEETESLSD 2323 Score = 42.4 bits (98), Expect = 0.002 Identities = 40/145 (27%), Positives = 67/145 (46%), Gaps = 22/145 (15%) Query: 285 KKEEGRAGAGLGDGERKTNDKDEK--KEDGKQAENDSSN--DDKTKKSEGDGDKEE---- 336 +K+ R L + R+ +K+EK +E+ K A S DD+ EG ++EE Sbjct: 2136 EKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDE---EEGGIEEEEVIPF 2192 Query: 337 --KKEDSEKEAKKSSKKRNRKHSGDDSFD---------EGSVSESESESESGQAEEEKEE 385 ++ KEAK+ K + + S D + E + E E + EEE+ E Sbjct: 2193 LKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEERE 2252 Query: 386 AEALKEKEKPKEEEWEKPKDAAGLE 410 E +E+E+ +EEE E+ ++ G E Sbjct: 2253 EEEEREEEEVREEEEERKEEEEGEE 2277 Score = 40.8 bits (94), Expect = 0.006 Identities = 102/512 (19%), Positives = 202/512 (39%), Gaps = 69/512 (13%) Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA-ENDSS 320 E + R+L++EE+ QAG+ P + E DK K E+ KQ EN S Sbjct: 1484 EWEKRLLQEEEKLHQAGEKLSPEE-------------EMLQEDKKLKWEEWKQVWENMLS 1530 Query: 321 NDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAE 380 + K ++ + + + ++E S + +K + + + + + +E +A+ Sbjct: 1531 SKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQ 1590 Query: 381 EEK---EEAEALKEKEKPKEEEWEKPKDA-AGLECKPRPLHKTCSLFMRNIAPNISRAEI 436 EE+ +E E L ++E+ +E K A + R + + F + R E Sbjct: 1591 EERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEK 1650 Query: 437 IS------------LCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNI 484 +S L K++ +VA E + ++ + V + ++E+ QN+ Sbjct: 1651 LSQEAEKLAQKRKKLAKKWE---KVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL 1707 Query: 485 RLRECELSPGVN------RDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWA 538 +E EL+ + +L+ + +N + ++V KLA ++ W Sbjct: 1708 DWQEKELAQELEELEWDMEELSWKEEELN--QEEGKLVEEKKKLAE------EEEALAWQ 1759 Query: 539 SEPGTPPLPTSLPSQNPILKNITDYLIE--EVSAEEEELLGSSGGAPPEEPPKEGNPAEI 596 E + T L + +L + L + E EEEE LG E+ K E Sbjct: 1760 REKLSEE-ETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818 Query: 597 NVERDEKLIKVLDKLLLYLRIVHSLDYYNTCE------YPNEDEMPNRCGIIHVRGPMPP 650 + E+L K +K++LY + + + N + E+ + N+ + H + + Sbjct: 1819 WINSMEELTK--NKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQ 1876 Query: 651 NRISHGEVLEWQKTFEEKLT----PLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQE 706 + G + EEKLT ++ +E L+E E + + +VE + ++ Sbjct: 1877 VKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLV-------QVEDSLAKKQEK 1929 Query: 707 LGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEK 738 L ++K L +G + +R + EK Sbjct: 1930 LAQEKMKLALEKAMVQGKKRLRGELDIAKEEK 1961 Score = 39.7 bits (91), Expect = 0.012 Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 43/177 (24%) Query: 234 DNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGA 293 ++LL +++K +++ + + E E ++R +EEEE + + GE + E+ Sbjct: 2231 ESLLDELEKQESLSSEEEEEREEEEEREEEEVR---EEEEERKEEEEGEEKQVEK----- 2282 Query: 294 GLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRN 353 + E+K K++KKE+ ++ K E +KEE + E E Sbjct: 2283 --EEEEKKKKKKEKKKEEVQE------------KEEVFEEKEEIMSEEETE--------- 2319 Query: 354 RKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLE 410 S+S+ E E ES EEE + + + +KEK + + ++ K G E Sbjct: 2320 ------------SLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRE 2364 Score = 35.8 bits (81), Expect = 0.18 Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 2/97 (2%) Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSG--DDSFDEGSVSESESESESGQAEE 381 + +K GDK ++K S+ + +S + + + D+ + S+S E E + E Sbjct: 2198 RKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER 2257 Query: 382 EKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHK 418 E+EE +E+ K +EE EK + E K + K Sbjct: 2258 EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294 Score = 31.2 bits (69), Expect = 4.4 Identities = 39/154 (25%), Positives = 69/154 (44%), Gaps = 22/154 (14%) Query: 257 MEGGTENDLRILE-QEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315 ++G T+ +R E EEEQA K +A LG E + K KK + Sbjct: 1329 IQGVTQEVIRHKEVMPREEEQAQK----------KARDMLGLEETQVILKKGKKVIFLEP 1378 Query: 316 ENDSSNDDKTKKSEGDGDKEEKK--EDSEKEAKKSSKKRNR--KHSGDDSFDEGSVSESE 371 N + + +KK EEKK + S K+ +K+ +K + K + + +E +SE Sbjct: 1379 GNVTMGKEISKK-------EEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEV 1431 Query: 372 SESESGQAEEEKEEAEALKEKEKPKEEEWEKPKD 405 E + + + K+E + + + P ++W+K D Sbjct: 1432 EEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWD 1465 Score = 30.0 bits (66), Expect = 9.8 Identities = 19/85 (22%), Positives = 43/85 (50%) Query: 270 QEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE 329 ++EEEE+ K E K+E + E ++++ + ++ E +S + ++ E Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340 Query: 330 GDGDKEEKKEDSEKEAKKSSKKRNR 354 + K+EK+ +++ +KS + R R Sbjct: 2341 KEILKKEKQFKLQEQRRKSLRGRER 2365 >gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo sapiens] Length = 1094 Score = 61.6 bits (148), Expect = 3e-09 Identities = 44/150 (29%), Positives = 72/150 (48%), Gaps = 8/150 (5%) Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGD-GERKTNDKDEKKEDGKQAENDSSNDD- 323 + + EEEE + S+ E G G+ GE +++D ++ + +++S + Sbjct: 674 KFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESG 733 Query: 324 -KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD-EGSVSESESESESGQAEE 381 + K++ K + K DSE K++ K + S D+S E S S+SESESE E Sbjct: 734 LENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESE---PES 790 Query: 382 EKEEAEALKEKE-KPKEEEWEKPKDAAGLE 410 E E KEKE K K++ KD + L+ Sbjct: 791 ESESRRVTKEKEKKTKQDRTPLTKDVSLLD 820 Score = 39.7 bits (91), Expect = 0.012 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 4/96 (4%) Query: 314 QAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRK-HSGDDSFDEGSVSESES 372 +A+ ++S +SE + D + DSE E+ S ++ GD + D S SE Sbjct: 665 KAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQ 724 Query: 373 ESESGQ---AEEEKEEAEALKEKEKPKEEEWEKPKD 405 +SESG+ E ++ K K K E+ EK + Sbjct: 725 DSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENE 760 Score = 38.1 bits (87), Expect = 0.036 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 1/80 (1%) Query: 334 KEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKE 393 KE K+ + K + +DS D S SESES SESG+ E EE ++ ++ Sbjct: 658 KEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSS 717 Query: 394 KPKEEEWEKPKD-AAGLECK 412 + E + +GLE K Sbjct: 718 EDSSSEQDSESGRESGLENK 737 >gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a [Homo sapiens] Length = 845 Score = 61.2 bits (147), Expect = 4e-09 Identities = 65/267 (24%), Positives = 119/267 (44%), Gaps = 32/267 (11%) Query: 148 VMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVG 207 + KTF E L D E E V + + + ++QQ + +D R K D+ G Sbjct: 37 IKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKK----KRDTRKGRRKKDVDDDG 92 Query: 208 KRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRI 267 + ++ L RL+ LS+ + D+ D + K +GG I Sbjct: 93 EEKE-----LMERLKK-LSVPTS----------DEEDEVPAPKPRGGKKTKGGNVFAALI 136 Query: 268 LEQ-EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326 +Q EEEEE+ P +P+K E+ R + + ++ K + GK+ ++ + K Sbjct: 137 QDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPA----LKGKKGKEEKSKGKAKPQNK 192 Query: 327 KSEGDGDKEEKKED--SEKEAKKSSKKRNRK-HSGDDSFDEGSVSESESESESGQAEEEK 383 + D ++E+K+E+ EKE K K++ +K G + EG E E E G+++ + Sbjct: 193 FAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEG----EEEEEEGGESKADD 248 Query: 384 EEAEALKEKEKPKEEEWEKPKDAAGLE 410 A K+++K +++ E + A L+ Sbjct: 249 PYAHLSKKEKKKLKKQMEYERQVASLK 275 Score = 35.4 bits (80), Expect = 0.23 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 11/121 (9%) Query: 295 LGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNR 354 +GDGE T+ D+ + GK+ D K KK+ + E K+ E+E K++ + Sbjct: 15 IGDGE-STSPSDKVVKKGKK-------DKKIKKTFFEELAVEDKQAGEEEKVLKEKEQQQ 66 Query: 355 KHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKP---KEEEWEKPKDAAGLEC 411 + + + + + EEKE E LK+ P +E+E PK G + Sbjct: 67 QQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKPRGGKKT 126 Query: 412 K 412 K Sbjct: 127 K 127 Score = 32.3 bits (72), Expect = 2.0 Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 13/132 (9%) Query: 296 GDGERKTNDKDEKKEDGKQAENDSSNDDK-TKKSEGDGDKEEKK------------EDSE 342 G+ E+ +K+++++ +Q + + K +K + D D EEK+ D E Sbjct: 53 GEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEE 112 Query: 343 KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEK 402 E + +K G + F +SE E E + + + E + + EE+ Sbjct: 113 DEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPA 172 Query: 403 PKDAAGLECKPR 414 K G E K + Sbjct: 173 LKGKKGKEEKSK 184 Score = 32.0 bits (71), Expect = 2.6 Identities = 34/156 (21%), Positives = 64/156 (41%), Gaps = 26/156 (16%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328 +Q E E G GE + + G D + K +E + KQA ++K K Sbjct: 7 QQPPEPEWIGD-GESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQA----GEEEKVLKE 61 Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE---- 384 + +++++++ +++ K+ ++K RK DD +E + E + ++EE E Sbjct: 62 K---EQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAP 118 Query: 385 --------------EAEALKEKEKPKEEEWEKPKDA 406 A + E+ +EEE PK A Sbjct: 119 KPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPA 154 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 58.9 bits (141), Expect = 2e-08 Identities = 49/159 (30%), Positives = 73/159 (45%), Gaps = 15/159 (9%) Query: 269 EQEEEEEQAGKPG-EPSKKEEGRAGAGLGDGE-RKTNDKDEKKEDGKQAENDSSNDDKTK 326 EQE+E + G+PG +P K++E R G G+ RK+ D + E+ Q + +++ + Sbjct: 926 EQEKEAGEPGRPGTKPPKRDEER---GKTQGKHRKSFALDSEGEEASQESSSEKDEEDDE 982 Query: 327 KSEGDGDKEE-----KKE----DSEKEAKKSSKKRNRKHSGDDSFDEGSVSESE-SESES 376 + E D D+EE KKE D E E SS K + D D S SES S S S Sbjct: 983 EDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSS 1042 Query: 377 GQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRP 415 + + + E E+E E+ + AA P P Sbjct: 1043 SSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPP 1081 Score = 40.4 bits (93), Expect = 0.007 Identities = 37/165 (22%), Positives = 67/165 (40%), Gaps = 8/165 (4%) Query: 279 KPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK--QAENDSSNDDKTKKSEGDGDKEE 336 K G + E G+GL R + K ++KE + +A + T E + D E+ Sbjct: 868 KSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQ 927 Query: 337 KKEDSE------KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALK 390 +KE E K K+ ++ + SF S E S+ S + +EE +E + Sbjct: 928 EKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEED 987 Query: 391 EKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAE 435 E + + +K + + E + CSL+ + N S ++ Sbjct: 988 EDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSD 1032 Score = 36.2 bits (82), Expect = 0.14 Identities = 57/241 (23%), Positives = 87/241 (36%), Gaps = 64/241 (26%) Query: 190 AHKDEEWFRSKYHPDEVGK------RRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKA 243 A +DE+ + E G+ +R E RG Q + R +L G ++A Sbjct: 918 AEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEG---------EEA 968 Query: 244 DAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTN 303 +++ K E E D ++EE + T Sbjct: 969 SQ-----ESSSEKDEEDDEEDEEDEDREEAVD--------------------------TT 997 Query: 304 DKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD 363 K+ + DG+ E+DSS+ + ++ DG+ DS +++ SS + S S Sbjct: 998 KKETEVSDGEDEESDSSS-KCSLYADSDGE-----NDSTSDSESSSSSSSSSSSSSSSSS 1051 Query: 364 EGSVSESESESESGQAEEEKEEAEALKEKEKPKEE---------EWEKPKDAAGLECKPR 414 S S SES SE EEE+E AL P E E P+ AG P Sbjct: 1052 SSSSSSSESSSED---EEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPL 1108 Query: 415 P 415 P Sbjct: 1109 P 1109 Score = 32.7 bits (73), Expect = 1.5 Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 13/69 (18%) Query: 759 PALPEIKPAQPPGPAQILPPGLTPGLP--YPHQTPQGLMPYGQPRPPILGYGAGAVRPAV 816 P P+ P PP P PP LP YP P L+P PRP G P Sbjct: 598 PTPPQQPPPPPPPPPP--PPPYLASLPLGYPPHQPAYLLP---PRPD------GPPPPEY 646 Query: 817 PTGGPPYPH 825 P PP PH Sbjct: 647 PPPPPPPPH 655 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 58.5 bits (140), Expect = 3e-08 Identities = 45/177 (25%), Positives = 79/177 (44%), Gaps = 23/177 (12%) Query: 260 GTENDLRILEQEEEEEQAGKPGEPSKKEEGR-----------------AGAGLGDGERKT 302 G ++++R E+E E + GK S++++ R G GERK Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92 Query: 303 NDKDEKK----EDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKK-RNRKHS 357 +++ KK ++ K+ E K KK G KE K+ + ++E K+ +K R RK Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152 Query: 358 GDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPR 414 + E + + G+ EEE++E E KE++K + E+ K+ E + R Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKEKER-KERKKRERNRKERKKERERKERRER 208 Score = 57.4 bits (137), Expect = 6e-08 Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 13/150 (8%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328 E++ E + K GE K+E R ++ +K+++K+ K+ +S + K ++ Sbjct: 76 ERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER 135 Query: 329 EGDGDKEEKKE------DSEKE-AKKSSKKRNRKHSGDDSFDEGSVSESE------SESE 375 + + +EE+KE + EKE +K KKR RK G+ + E + E Sbjct: 136 KEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195 Query: 376 SGQAEEEKEEAEALKEKEKPKEEEWEKPKD 405 + E KE E KE++K +E + E+ KD Sbjct: 196 RKKERERKERRERKKERKKKEERKKERQKD 225 Score = 57.4 bits (137), Expect = 6e-08 Identities = 35/153 (22%), Positives = 76/153 (49%), Gaps = 3/153 (1%) Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSN 321 E + + +E+E ++ + + KKE+ G +G+ + ++ K+E+ K+ E Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153 Query: 322 DDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381 +K ++ + + K E+K+ EKE ++ K+R + + + E E E + + +E Sbjct: 154 REKERERK-ERKKRERKQVGEKEEERKEKERKERKKRERNRKERK-KERERKERRERKKE 211 Query: 382 EKEEAEALKEKEKPKEEEWEKPKDAAGLECKPR 414 K++ E KE++K ++ W + K+ E K R Sbjct: 212 RKKKEERKKERQKDRQTNW-REKERGKRERKER 243 Score = 56.6 bits (135), Expect = 1e-07 Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 6/142 (4%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDE------KKEDGKQAENDSSND 322 ++ +E E+ K + KKE GR + ERK K E +K++ ++ E + Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKER 163 Query: 323 DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE 382 K ++ + +EE+KE KE KK + R + + + + + E + E + Sbjct: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQ 223 Query: 383 KEEAEALKEKEKPKEEEWEKPK 404 K+ +EKE+ K E E+ K Sbjct: 224 KDRQTNWREKERGKRERKERKK 245 Score = 42.4 bits (98), Expect = 0.002 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 3/92 (3%) Query: 310 EDGKQAENDSSNDDKTKKSEGDGDK--EEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSV 367 + G Q+E + + EG ++ E KKE E+E +K +++ RK +G Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90 Query: 368 SESESESESGQAEEEKEEAEALKEKEKPKEEE 399 + E E + + E+E +E E KEK K KE++ Sbjct: 91 KKEERERKKRRREKENKEGEE-KEKRKKKEKK 121 Score = 40.0 bits (92), Expect = 0.009 Identities = 21/85 (24%), Positives = 43/85 (50%) Query: 6 DEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRER 65 +E R R + R++ + ++ RER ER++ + E + R+ + R E + +RNR+ER Sbjct: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196 Query: 66 FSPPRHELSPPQKRMRRDWDEHSSD 90 + +K+ R+ +E + Sbjct: 197 KKERERKERRERKKERKKKEERKKE 221 Score = 37.4 bits (85), Expect = 0.061 Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 5/77 (6%) Query: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERF 66 E +RRR+K +E + ++ ++++++ RG R G+ER + E + +R RER Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERG-----RTSKEGKERERKEERKREERKERERK 150 Query: 67 SPPRHELSPPQKRMRRD 83 R + ++R +R+ Sbjct: 151 KEEREKERERKERKKRE 167 Score = 37.4 bits (85), Expect = 0.061 Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 2/61 (3%) Query: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRS--RGEYRDYDRNRRE 64 E +R+ R K R R + + RER ERR ++ +R +ER+ + +R+ +R +RE Sbjct: 180 EKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRE 239 Query: 65 R 65 R Sbjct: 240 R 240 Score = 36.6 bits (83), Expect = 0.10 Identities = 21/102 (20%), Positives = 52/102 (50%), Gaps = 2/102 (1%) Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315 + E + + R E+E +E + + + +KEE R + +++ ++ E+K++ ++ Sbjct: 144 RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK 203 Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDS--EKEAKKSSKKRNRK 355 E ++ KK E ++++ ++ + EKE K +K +K Sbjct: 204 ERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245 Score = 35.4 bits (80), Expect = 0.23 Identities = 17/63 (26%), Positives = 37/63 (58%), Gaps = 1/63 (1%) Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNR 62 +S+ + +RR R+K +RER + +R RER ++ + + E +R + RR + ++ + Sbjct: 56 ESERKKERREREKRKRER-EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEK 114 Query: 63 RER 65 R++ Sbjct: 115 RKK 117 Score = 33.9 bits (76), Expect = 0.68 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 8/66 (12%) Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER---RSRGEYRDYD 59 + + E + R+ K RE RER++R+R +RE +R RER +GE + + Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKR-----EREKERKRERGKKEKKGERKKEE 94 Query: 60 RNRRER 65 R R++R Sbjct: 95 RERKKR 100 Score = 32.3 bits (72), Expect = 2.0 Identities = 20/79 (25%), Positives = 41/79 (51%), Gaps = 5/79 (6%) Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNR 62 + + E +R+ K ++ER S+E ER R + +R+ + +ER + E R+ +R R Sbjct: 106 NKEGEEKEKRKKKEKKERG--RTSKEGKERERKE---ERKREERKERERKKEEREKERER 160 Query: 63 RERFSPPRHELSPPQKRMR 81 +ER R ++ ++ + Sbjct: 161 KERKKRERKQVGEKEEERK 179 Score = 32.0 bits (71), Expect = 2.6 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 7/85 (8%) Query: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGE-----YRDYDRN 61 E R ++ RER + + ER ER R + +RE +R R+ R + E ++ +R Sbjct: 122 ERGRTSKEGKERERKEERKREERKERERKKE--EREKERERKERKKRERKQVGEKEEERK 179 Query: 62 RRERFSPPRHELSPPQKRMRRDWDE 86 +ER + E + +++ R+ E Sbjct: 180 EKERKERKKRERNRKERKKERERKE 204 Score = 31.6 bits (70), Expect = 3.4 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 25 RSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDW 84 R RER+ R + +RE +R +ERR R ++ +RER + E +K+ R Sbjct: 39 REREREIETRKEGKKERESERKKERRER------EKRKREREKERKRERGKKEKKGERKK 92 Query: 85 DE 86 +E Sbjct: 93 EE 94 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 58.5 bits (140), Expect = 3e-08 Identities = 47/181 (25%), Positives = 83/181 (45%), Gaps = 7/181 (3%) Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315 K E G E + + E+E++ ++ + +K+E + G R+ K E+KE ++ Sbjct: 68 KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE--RER 125 Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375 EN + K KK ++E+K + E+ K+ K++ RK + E + E + E E Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKER-GKRERKRKKRKKEEREKKRERNRKERKKERE 184 Query: 376 SGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAE 435 + E K+E + KE+ K KE + ++ D RPL + S F R + R Sbjct: 185 RKERRERKKERK--KERRKKKERKKDRKTDRQTDSQVFRPLRE--SAFNRVTVTGVFRYR 240 Query: 436 I 436 I Sbjct: 241 I 241 Score = 53.5 bits (127), Expect = 8e-07 Identities = 30/136 (22%), Positives = 63/136 (46%), Gaps = 3/136 (2%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328 +++ ++ + GK E +KE + + ER+ K++KK + KQ + K KK Sbjct: 63 KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQR---GRRERKKKKE 119 Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEA 388 + ++E K+ K K+ KKR ++ + + + + E + + E+ E Sbjct: 120 RKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKER 179 Query: 389 LKEKEKPKEEEWEKPK 404 KE+E+ + E +K + Sbjct: 180 KKERERKERRERKKER 195 Score = 52.4 bits (124), Expect = 2e-06 Identities = 31/145 (21%), Positives = 71/145 (48%), Gaps = 9/145 (6%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328 ++E E+E+ + G+ KK+ + G + ERK ++++++++ ++ E +K K+ Sbjct: 47 KREREKERKRERGKKEKKKRKKRERGK-ERERKRKEREKQRKERREKERRKRKKEKKKRE 105 Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAE-------- 380 + E+K+ E++ ++ K+ R+ + E + E E G+ E Sbjct: 106 RKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKK 165 Query: 381 EEKEEAEALKEKEKPKEEEWEKPKD 405 EE+E+ KE+ KE E ++ ++ Sbjct: 166 EEREKKRERNRKERKKERERKERRE 190 Score = 52.0 bits (123), Expect = 2e-06 Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 9/134 (6%) Query: 271 EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEG 330 + E E+ + E K++ R + +K K +K+E GK+ E K+ E Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERER--------KRKER 82 Query: 331 DGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALK 390 + ++E++E ++ KK KKR RK G + E E E+ Q E K + K Sbjct: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRE-RKKKKERKERERENKQRRERKRKKRRKK 141 Query: 391 EKEKPKEEEWEKPK 404 ++ K ++ E E+ K Sbjct: 142 KRRKERKREKERGK 155 Score = 38.1 bits (87), Expect = 0.036 Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 13/93 (13%) Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRE--------RDERRRGDDWNDREWDRGRERRSRGE 54 +S+ + +RR R+K +RER + +R RE R +R RG + + +R ++R+ R E Sbjct: 33 ESERKKERREREKRKRER-EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91 Query: 55 ----YRDYDRNRRERFSPPRHELSPPQKRMRRD 83 R ++ +RER R E ++R R+ Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERE 124 Score = 37.0 bits (84), Expect = 0.080 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 5/87 (5%) Query: 9 DRRRRDKFRRERSDYDRSRE--RDERRRGDDWNDRE---WDRGRERRSRGEYRDYDRNRR 63 +R R +K RRER R ++ R ER+R + RE R +E R + R+ ++ Sbjct: 122 ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK 181 Query: 64 ERFSPPRHELSPPQKRMRRDWDEHSSD 90 ER R E +K+ RR E D Sbjct: 182 ERERKERRERKKERKKERRKKKERKKD 208 Score = 36.6 bits (83), Expect = 0.10 Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 4/77 (5%) Query: 10 RRRRDKFR-RERSDYDRSRERDERRRGDDWNDREWDRGRERRSRG---EYRDYDRNRRER 65 R++R++ + RER +R ++R ERR + ++ + RER+ RG + +R RER Sbjct: 66 RKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERER 125 Query: 66 FSPPRHELSPPQKRMRR 82 + R E ++R ++ Sbjct: 126 ENKQRRERKRKKRRKKK 142 Score = 36.6 bits (83), Expect = 0.10 Identities = 19/76 (25%), Positives = 41/76 (53%), Gaps = 4/76 (5%) Query: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERF 66 E R+ R+K R+ER + +R + + E+++ +R+ RER+ + E ++ +R ++R Sbjct: 76 ERKRKEREKQRKERREKERRKRKKEKKK----RERKQRGRRERKKKKERKERERENKQRR 131 Query: 67 SPPRHELSPPQKRMRR 82 R + ++R R Sbjct: 132 ERKRKKRRKKKRRKER 147 Score = 36.2 bits (82), Expect = 0.14 Identities = 21/90 (23%), Positives = 38/90 (42%), Gaps = 7/90 (7%) Query: 313 KQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES 372 K S K ++ +E +KE + KK KKR ++ + G E + Sbjct: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKR-------ERGKERERKR 79 Query: 373 ESESGQAEEEKEEAEALKEKEKPKEEEWEK 402 + Q +E +E+ ++KEK K E ++ Sbjct: 80 KEREKQRKERREKERRKRKKEKKKRERKQR 109 Score = 35.4 bits (80), Expect = 0.23 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Query: 333 DKEEKKEDSEKEAKKSSKKRNRKHS-GDDSFDEGSVSESESESESGQAEEEKEEAEAL-K 390 + E KKE E+E +K +++ RK G + E E E + E EK+ E K Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92 Query: 391 EKEKPKEEEWEKPKDAAG 408 E+ K K+E+ ++ + G Sbjct: 93 ERRKRKKEKKKRERKQRG 110 Score = 35.0 bits (79), Expect = 0.30 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Query: 10 RRRRDKFRRERSDYDRSRERDERRRGDDWNDRE-WDRGRERRSRGEYRDYDRNRRERFSP 68 + RR+K RR+R + RER +R R + +E +R RE + R E + R +++R Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146 Query: 69 PRHELSPPQKRMRR 82 + E ++ +R Sbjct: 147 RKREKERGKRERKR 160 Score = 33.9 bits (76), Expect = 0.68 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 5/85 (5%) Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDY---- 58 + + E R R K +++R +R +ER ER+R + R+ R +ERR R + + Sbjct: 49 EREKERKRERGKKEKKKRKKRERGKER-ERKRKEREKQRKERREKERRKRKKEKKKRERK 107 Query: 59 DRNRRERFSPPRHELSPPQKRMRRD 83 R RRER + + + RR+ Sbjct: 108 QRGRRERKKKKERKERERENKQRRE 132 Score = 33.1 bits (74), Expect = 1.2 Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 7/84 (8%) Query: 5 DDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGE-------YRD 57 + E +R+++K +RER R + ++ R + + + R R+R+ R + R+ Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150 Query: 58 YDRNRRERFSPPRHELSPPQKRMR 81 +R +RER R + +KR R Sbjct: 151 KERGKRERKRKKRKKEEREKKRER 174 Score = 30.8 bits (68), Expect = 5.7 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60 E R++R K RE+ +ER + R + +R+ +R +ERR + E R DR Sbjct: 157 ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE-RKKDR 209 Score = 30.0 bits (66), Expect = 9.8 Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 2/63 (3%) Query: 10 RRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPP 69 + R+K +RER+ +R +ER+ + R + +R+ +R R+++ R + R DR + P Sbjct: 165 KEEREK-KRERNRKERKKERERKERRERKKERKKER-RKKKERKKDRKTDRQTDSQVFRP 222 Query: 70 RHE 72 E Sbjct: 223 LRE 225 >gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] Length = 237 Score = 58.5 bits (140), Expect = 3e-08 Identities = 44/147 (29%), Positives = 71/147 (48%), Gaps = 22/147 (14%) Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKT 325 + L + EE+ E K E +++ K EKK+ G+ + + SS+ D + Sbjct: 46 KALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSS 105 Query: 326 KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385 S D + E+K K+ K+ KK+NR H +S S+SE+ES+S+ Sbjct: 106 SSSS-DSEDEDK-----KQGKRRKKKKNRSHKSSES----SMSETESDSK---------- 145 Query: 386 AEALKEKEKPKEEEWEKPKDAAGLECK 412 ++LK+K+K K+ EK KD GL K Sbjct: 146 -DSLKKKKKSKDGT-EKEKDIKGLSKK 170 Score = 54.3 bits (129), Expect = 5e-07 Identities = 43/161 (26%), Positives = 80/161 (49%), Gaps = 11/161 (6%) Query: 257 MEGGTENDLRILEQEEEEEQAGK-PGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315 + G + + +++E++++G+ S + + + + E K K KK+ + Sbjct: 71 LSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSH 130 Query: 316 ENDSSNDDKTKKSEGDGDKEEKKE----DSEKEAKKSSKKRNRKHSGDDSFDEGSVSESE 371 ++ S+ +T+ D K++KK + EK+ K SKKR + +S D S+SESE Sbjct: 131 KSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKR-KMYSEDKPLSSESLSESE 189 Query: 372 SESE----SGQAEEEKEEA-EALKEKEKPKEEEWEKPKDAA 407 E ++ EE+E+A E K+K+K K+ +K K AA Sbjct: 190 YIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAA 230 >gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] Length = 247 Score = 58.5 bits (140), Expect = 3e-08 Identities = 44/147 (29%), Positives = 71/147 (48%), Gaps = 22/147 (14%) Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKT 325 + L + EE+ E K E +++ K EKK+ G+ + + SS+ D + Sbjct: 56 KALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSS 115 Query: 326 KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385 S D + E+K K+ K+ KK+NR H +S S+SE+ES+S+ Sbjct: 116 SSSS-DSEDEDK-----KQGKRRKKKKNRSHKSSES----SMSETESDSK---------- 155 Query: 386 AEALKEKEKPKEEEWEKPKDAAGLECK 412 ++LK+K+K K+ EK KD GL K Sbjct: 156 -DSLKKKKKSKDGT-EKEKDIKGLSKK 180 Score = 54.3 bits (129), Expect = 5e-07 Identities = 43/161 (26%), Positives = 80/161 (49%), Gaps = 11/161 (6%) Query: 257 MEGGTENDLRILEQEEEEEQAGK-PGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315 + G + + +++E++++G+ S + + + + E K K KK+ + Sbjct: 81 LSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSH 140 Query: 316 ENDSSNDDKTKKSEGDGDKEEKKE----DSEKEAKKSSKKRNRKHSGDDSFDEGSVSESE 371 ++ S+ +T+ D K++KK + EK+ K SKKR + +S D S+SESE Sbjct: 141 KSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKR-KMYSEDKPLSSESLSESE 199 Query: 372 SESE----SGQAEEEKEEA-EALKEKEKPKEEEWEKPKDAA 407 E ++ EE+E+A E K+K+K K+ +K K AA Sbjct: 200 YIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAA 240 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 57.4 bits (137), Expect = 6e-08 Identities = 34/157 (21%), Positives = 73/157 (46%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317 +G E + + +E+E E + + E ++E R + E++ + E++ D + Sbjct: 295 KGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRT 354 Query: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377 + D+ ++ + D D+E + ++ ++ K R+R+ + + E E E E Sbjct: 355 KERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERE 414 Query: 378 QAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPR 414 + E + E E K+K++ +EE+ E + LE K R Sbjct: 415 REREREREREREKDKKRDREEDEEDAYERRKLERKLR 451 Score = 56.6 bits (135), Expect = 1e-07 Identities = 50/235 (21%), Positives = 98/235 (41%), Gaps = 33/235 (14%) Query: 204 DEVGKRRQEARGALQNRLRVFLSLM-----ETGWFDNLLLDIDKADAIVKMLDAAVIKME 258 +E +R Q +GA++ +R + S + E+ K D + A +I Sbjct: 198 EETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYP 257 Query: 259 GGTENDLRILEQEEE-------------------EEQAGKPG----EPSKKEEGRAGAGL 295 T+ D+ +E EE+ EE+ GK E K+ R Sbjct: 258 LITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERE 317 Query: 296 GDGERKTNDKDEKKEDGKQAENDSSND-----DKTKKSEGDGDKEEKKEDSEKEAKKSSK 350 + ER+ +++ ++E ++ E + + D+ + E D D++ +++ + S + Sbjct: 318 RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDR 377 Query: 351 KRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKD 405 ++R S + S D E E E E + E + E E +E+E+ +E E +K +D Sbjct: 378 NKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRD 432 Score = 47.0 bits (110), Expect = 8e-05 Identities = 31/145 (21%), Positives = 69/145 (47%), Gaps = 8/145 (5%) Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER-KTNDKDEKKEDGKQAENDSS 320 E + R E+E E E+ + + ++E R D +R K D+D +E + + + S Sbjct: 319 ERERREREREREREREREKEKERERERERDR----DRDRTKERDRDRDRERDRDRDRERS 374 Query: 321 ND---DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377 +D D+++ E D+E ++E + ++ ++R R+ + + E + + + Sbjct: 375 SDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDRE 434 Query: 378 QAEEEKEEAEALKEKEKPKEEEWEK 402 + EE+ E L+ K + KE +++ Sbjct: 435 EDEEDAYERRKLERKLREKEAAYQE 459 Score = 44.7 bits (104), Expect = 4e-04 Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 3/91 (3%) Query: 3 DSDDEYDRRR-RDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-RSRGEYRDYDR 60 + + E +R R RD+ R + D DR RERD R + +DR DR R R +SR R+ +R Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERER 397 Query: 61 NR-RERFSPPRHELSPPQKRMRRDWDEHSSD 90 R RER E ++R R E D Sbjct: 398 EREREREREREREREREREREREREREREKD 428 Score = 43.1 bits (100), Expect = 0.001 Identities = 30/84 (35%), Positives = 46/84 (54%), Gaps = 9/84 (10%) Query: 7 EYDRRRRDKFR---RERSDYDRSRERDERRRGDDWNDREWDRGRER-RSRGEYRDYDRNR 62 E +RR R++ R RER + +R RER+ R + +RE +R R+R R++ RD DR R Sbjct: 306 EKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRER 365 Query: 63 -----RERFSPPRHELSPPQKRMR 81 RER S + S +++ R Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSR 389 Score = 40.0 bits (92), Expect = 0.009 Identities = 30/160 (18%), Positives = 72/160 (45%), Gaps = 14/160 (8%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER-----KTNDKDEKKEDGKQAENDSSND- 322 ++E + ++ + K+ R+ D ER + +++ ++E ++ E + + Sbjct: 362 DRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERER 421 Query: 323 DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVS--------ESESES 374 ++ ++ + D+EE +ED+ + K K R ++ + + + E E+E Sbjct: 422 EREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAER 481 Query: 375 ESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPR 414 E + E +EA+ LKE + +++ + PK G + R Sbjct: 482 EEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKR 521 Score = 39.7 bits (91), Expect = 0.012 Identities = 31/91 (34%), Positives = 44/91 (48%), Gaps = 13/91 (14%) Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-----------RS 51 + + E +R R + RER + +R R+RD + D DRE DR R+R RS Sbjct: 326 EREREREREREKEKERER-ERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRS 384 Query: 52 RGEYRDYDRNR-RERFSPPRHELSPPQKRMR 81 R + RD +R R RER E ++R R Sbjct: 385 REKSRDRERERERERERERERERERERERER 415 Score = 39.7 bits (91), Expect = 0.012 Identities = 39/174 (22%), Positives = 79/174 (45%), Gaps = 12/174 (6%) Query: 264 DLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDD 323 ++R ++ E E+ + E ++E + L + D D+ ++D K S+ Sbjct: 465 EIRERKKTREYEKEAEREEERRREMAKEAKRL---KEFLEDYDDDRDDPKYYRG-SALQK 520 Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383 + + E + + +E+ EKE + ++R D E E E+E +++ Sbjct: 521 RLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQE 580 Query: 384 EEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTC---SLFMRNIAPNISRA 434 E+E +E+++ KEE+ E+P +E + P K C +L + AP++S A Sbjct: 581 PESEEEEEEKQEKEEKREEP-----MEEEEEPEQKPCLKPTLRPISSAPSVSSA 629 Score = 37.7 bits (86), Expect = 0.047 Identities = 29/83 (34%), Positives = 43/83 (51%), Gaps = 9/83 (10%) Query: 11 RRRDKFRRERSDYDRSRERD-ERRRGDDWNDREWDRGRER-RSRGEYRDYDRNRRERFSP 68 + R + +ER + +R RER+ ERR + +RE +R +E+ R R RD DR+R + Sbjct: 300 KERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDR 359 Query: 69 PRHELSPPQKRMRRDWD-EHSSD 90 R + RD D E SSD Sbjct: 360 DR------DRERDRDRDRERSSD 376 Score = 37.4 bits (85), Expect = 0.061 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 1/89 (1%) Query: 3 DSDDEYDRRRRDKFRRERS-DYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRN 61 D + E +R R + RER + +R RER+ R + D++ DR + E R +R Sbjct: 390 DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 449 Query: 62 RRERFSPPRHELSPPQKRMRRDWDEHSSD 90 RE+ + + L + R R+ E+ + Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKE 478 Score = 36.6 bits (83), Expect = 0.10 Identities = 24/62 (38%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Query: 4 SDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-RSRGEYRDYDRNR 62 SD DR R + R+R + +R RER+ R + +RE +R RER R R +D R+R Sbjct: 375 SDRNKDRSRSREKSRDR-EREREREREREREREREREREREREREREREREREKDKKRDR 433 Query: 63 RE 64 E Sbjct: 434 EE 435 Score = 35.0 bits (79), Expect = 0.30 Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 25/116 (21%) Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGR--------------- 47 + + E +R R + RER + +R RE+D++R ++ + ++R + Sbjct: 402 ERERERERERERERERER-EREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQER 460 Query: 48 ----ERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMR---RDWDEHSSDP-YHSG 95 E R R + R+Y++ ER R E++ KR++ D+D+ DP Y+ G Sbjct: 461 LKNWEIRERKKTREYEK-EAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRG 515 Score = 35.0 bits (79), Expect = 0.30 Identities = 28/147 (19%), Positives = 62/147 (42%), Gaps = 4/147 (2%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328 E+E E E+ + + +EE A ER+ ++ ++++ E + + + +K Sbjct: 416 EREREREREREKDKKRDREEDEEDAY----ERRKLERKLREKEAAYQERLKNWEIRERKK 471 Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEA 388 + +KE ++E+ + KR ++ D D + + + ++E EA Sbjct: 472 TREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEA 531 Query: 389 LKEKEKPKEEEWEKPKDAAGLECKPRP 415 + K ++EE E+ + E P P Sbjct: 532 DERDRKREKEELEEIRQRLLAEGHPDP 558 Score = 33.1 bits (74), Expect = 1.2 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 5/60 (8%) Query: 11 RRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-----RSRGEYRDYDRNRRER 65 R R++ R + +R RER+ R + +RE +R RE+ R E Y+R + ER Sbjct: 389 RDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLER 448 Score = 32.3 bits (72), Expect = 2.0 Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 7/59 (11%) Query: 6 DEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRE 64 D + + +K ++E+ + +ER ER +RE +R RERR R R+ +R R + Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRER-------ERERERERERREREREREREREREK 337 >gi|4557509 cylicin 2 [Homo sapiens] Length = 348 Score = 57.4 bits (137), Expect = 6e-08 Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 11/141 (7%) Query: 258 EGGTENDLRILEQEEE-------EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE 310 +GGTE D + +++ + E QA K E K E+G+ A GD E K KD K+ Sbjct: 210 KGGTEKDSKKGKKDSKKGKDSAIELQAVKADE-KKDEDGKKDANKGD-ESKDAKKDAKEI 267 Query: 311 DGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSES 370 K+ + D T D K+E K+D+ K+AKK +KK K S D D ++ Sbjct: 268 --KKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKK 325 Query: 371 ESESESGQAEEEKEEAEALKE 391 +++ ++ + ++ E+ +A K+ Sbjct: 326 DAKKDAKKNAKKDEKKDAKKK 346 Score = 56.2 bits (134), Expect = 1e-07 Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 19/153 (12%) Query: 269 EQEEEEEQAGKPGEPSKKE--EGRAGAGLGDGERKTNDKDEKK--EDGKQAENDSSNDDK 324 E E+E+ A K + KK+ +G+ A +GE+ +KD KK +D K+ ++ + Sbjct: 177 ESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQA 236 Query: 325 TK---KSEGDGDKEEKKEDSEKEAKKSS------KKRNRKHSGDDSFDEGSVSESESESE 375 K K + DG K+ K D K+AKK + KK +K S DS + V + + Sbjct: 237 VKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDA 296 Query: 376 SGQAEE------EKEEAEALKEKEKPKEEEWEK 402 + A++ EKE A++ K+ +K +++ +K Sbjct: 297 TKDAKKVAKKDTEKESADSKKDAKKNAKKDAKK 329 Score = 53.9 bits (128), Expect = 6e-07 Identities = 39/140 (27%), Positives = 68/140 (48%), Gaps = 13/140 (9%) Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKK----EDGKQAENDSSN 321 R +E + + + GK GE ++ + + E K KD KK E GK+ + D+ Sbjct: 103 RTVEVDSKAAEIGKKGEDKTTQKDTTDS---ESELKQGKKDSKKGKDIEKGKEEKLDAKK 159 Query: 322 DDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381 D K K + + K+ E ++ K +KK N+K D + +G S +ESE E G E+ Sbjct: 160 DSKKGKKDAEKGKDSATESEDE--KGGAKKDNKKDKKDSN--KGKDSATESEGEKGGTEK 215 Query: 382 EKEEAEALKEKEKPKEEEWE 401 + ++ + K+ +K K+ E Sbjct: 216 DSKKGK--KDSKKGKDSAIE 233 Score = 50.8 bits (120), Expect = 5e-06 Identities = 39/144 (27%), Positives = 70/144 (48%), Gaps = 9/144 (6%) Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKK 327 +E+ +EE+ K + SKK + A G ++K K+D K+ + D SN K Sbjct: 147 IEKGKEEKLDAK--KDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKD-SNKGKDSA 203 Query: 328 SEGDGDKEEKKEDSEKEAKKSSKKRN-----RKHSGDDSFDEGSVSESESESESGQAEEE 382 +E +G+K ++DS+K K S K ++ + D+ DE ++ ES A+++ Sbjct: 204 TESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKD 263 Query: 383 -KEEAEALKEKEKPKEEEWEKPKD 405 KE + K+K+KP + + D Sbjct: 264 AKEIKKGKKDKKKPSSTDSDSKDD 287 Score = 48.5 bits (114), Expect = 3e-05 Identities = 37/148 (25%), Positives = 74/148 (50%), Gaps = 10/148 (6%) Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGA----GLGDGERKTNDKDEKKEDGKQAENDSSND- 322 L+Q +++ + GK E K+E+ A G D E+ + E +++ A+ D+ D Sbjct: 134 LKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDK 193 Query: 323 -DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381 D K + + E +K +EK++KK K++ K D + + +V E + E G+ + Sbjct: 194 KDSNKGKDSATESEGEKGGTEKDSKKG--KKDSKKGKDSAIELQAVKADEKKDEDGKKDA 251 Query: 382 EK--EEAEALKEKEKPKEEEWEKPKDAA 407 K E +A K+ ++ K+ + +K K ++ Sbjct: 252 NKGDESKDAKKDAKEIKKGKKDKKKPSS 279 Score = 47.0 bits (110), Expect = 8e-05 Identities = 26/95 (27%), Positives = 47/95 (49%) Query: 308 KKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSV 367 KK + K + D+++ + K K+ K + KE K +KK ++K D + S Sbjct: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSA 175 Query: 368 SESESESESGQAEEEKEEAEALKEKEKPKEEEWEK 402 +ESE E + + +K++ ++ K K+ E E EK Sbjct: 176 TESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEK 210 Score = 38.5 bits (88), Expect = 0.027 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 7/82 (8%) Query: 279 KPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS------SNDDKTKKSEGDG 332 K G+ KK+ + D +K + KD K+ K A+ D+ S D K ++ D Sbjct: 268 KKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDA 327 Query: 333 DKEEKKEDSEKEAKKSSKKRNR 354 K+ KK +++K+ KK +KK+ + Sbjct: 328 KKDAKK-NAKKDEKKDAKKKGK 348 Score = 30.0 bits (66), Expect = 9.8 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Query: 349 SKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDA 406 SK G+D + ++SESE + G+ + +K K+ EK KEE+ + KD+ Sbjct: 109 SKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKG-----KDIEKGKEEKLDAKKDS 161 >gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo sapiens] Length = 1150 Score = 57.4 bits (137), Expect = 6e-08 Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 17/122 (13%) Query: 299 ERKTNDKDEKKED--GKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKH 356 ++K DK KK++ K+ E D D+ K GD ++KKED ++ K+ +K Sbjct: 798 DKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRK----- 852 Query: 357 SGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPK-EEEWEKPKDAAGLE--CKP 413 DDS D + E+E ++ Q E + EAE +++E + EEE K D + CK Sbjct: 853 --DDSKD-----DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKE 905 Query: 414 RP 415 RP Sbjct: 906 RP 907 Score = 34.3 bits (77), Expect = 0.52 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 3/90 (3%) Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWND--REWDRGRERRSRGEYRDYDR 60 + DDE D + K R+ D D+ +RDER++ D D ++ D E ++ EY + Sbjct: 817 ERDDETDEPK-PKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEA 875 Query: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSD 90 E R E ++ +RD + + + Sbjct: 876 EEAEDEEDDRDEEEMTKRDDKRDINRYCKE 905 Score = 30.4 bits (67), Expect = 7.5 Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 4/60 (6%) Query: 26 SRERDERRRGDDWNDREWDRGRER---RSRGEYRDYDRNRRERFSPPRHELSPPQKRMRR 82 SR RGD +R+ DR RER R R R R +R R PR E +R+RR Sbjct: 299 SRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQR-KRSRERSPRRERERSPRRVRR 357 >gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa [Homo sapiens] Length = 517 Score = 57.0 bits (136), Expect = 7e-08 Identities = 44/152 (28%), Positives = 72/152 (47%), Gaps = 19/152 (12%) Query: 263 NDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSND 322 ++LRI + E++ E + + S +E GR K K + G++ + +D Sbjct: 203 SELRIHDLEDDLEMSSDASDASGEEGGRVP--------KAKKKAPLAKGGRKKKKKKGSD 254 Query: 323 DKTKKSEGDGDKEEKKED-------SEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375 D+ + DGD E ++ D S +E +S K ++ G DE S S ESE E Sbjct: 255 DEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEE 314 Query: 376 SGQAEEEKEEAEALKEKEKPKEEEWEKPKDAA 407 EE+KEE E EK+ P +E ++ KD++ Sbjct: 315 K-PPEEDKEEEE---EKKAPTPQEKKRRKDSS 342 Score = 46.2 bits (108), Expect = 1e-04 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 14/116 (12%) Query: 288 EGRAGAGLGDGERKTNDKDEKKEDGKQAEN-----DSSNDDKTKKSEGDGDKEEKKEDSE 342 EG+ + DG + ++ E K Q E D +D + E +E+K+E+ E Sbjct: 267 EGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEE 326 Query: 343 KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEE 398 K+A +K+ RK S + ES+S ES E K+K PK E Sbjct: 327 KKAPTPQEKKRRKDSSE---------ESDSSEESDIDSEASSALFMAKKKTPPKRE 373 Score = 45.4 bits (106), Expect = 2e-04 Identities = 40/160 (25%), Positives = 68/160 (42%), Gaps = 30/160 (18%) Query: 263 NDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSND 322 N I++Q ++Q E K++ GR A E + +D ++ E A + S + Sbjct: 172 NHFSIMQQRRLKDQDQDEDEEEKEKRGRRKAS----ELRIHDLEDDLEMSSDASDASGEE 227 Query: 323 DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD-------EGSVSESESESE 375 G + K + AK KK+ +K S D++F+ EG + S+ Sbjct: 228 ---------GGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGS 278 Query: 376 SGQAEEEKEEAEALKEKEKPK----------EEEWEKPKD 405 S EE + +A+A +++E PK E E EKP + Sbjct: 279 SSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPE 318 Score = 39.7 bits (91), Expect = 0.012 Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 31/126 (24%) Query: 270 QEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE 329 QEE E +A P ++EEG G + +D E+ E+ K E Sbjct: 282 QEEPESKAKAP----QQEEGPKGVD------EQSDSSEESEEEKPPE------------- 318 Query: 330 GDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEAL 389 E+K+E+ EK+A +K+ RK S ++S S ES+ +SE+ A ++ Sbjct: 319 -----EDKEEEEEKKAPTPQEKKRRKDSSEES---DSSEESDIDSEASSALFMAKKKTPP 370 Query: 390 KEKEKP 395 K + KP Sbjct: 371 KRERKP 376 Score = 36.6 bits (83), Expect = 0.10 Identities = 40/146 (27%), Positives = 58/146 (39%), Gaps = 18/146 (12%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317 EG D + EE EE+ KP E K+EE E+K EKK +E Sbjct: 296 EGPKGVDEQSDSSEESEEE--KPPEEDKEEE---------EEKKAPTPQEKKRRKDSSEE 344 Query: 318 DSSNDDKTKKSEGDGD--KEEKKEDSEKEAKKS-SKKRNRKHSGDDSFDEGSVSE----S 370 S+++ SE +KK ++E K S R G S + GS S + Sbjct: 345 SDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAA 404 Query: 371 ESESESGQAEEEKEEAEALKEKEKPK 396 S+ E G+ E A+ L+ P+ Sbjct: 405 ASKLEQGKRVSEMPAAKRLRLDTGPQ 430 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 56.6 bits (135), Expect = 1e-07 Identities = 49/186 (26%), Positives = 81/186 (43%), Gaps = 23/186 (12%) Query: 251 DAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE 310 DA + E + +++ +EEE+ Q K EP KK E + + K E+K+ Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE--------EEKAPATPKTEEKK 857 Query: 311 DGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRK------------HSG 358 D K+ E K K E EK ++S+ EAKK + +K Sbjct: 858 DSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVK 917 Query: 359 DDSFDEGSVSESESESESGQAEEEK---EEAEALKEKEKPKEEEWEKPKDAAGLECKPRP 415 +D+ + ++ E + +A+E E+ EA EK+ KEE+ +KP++ E K + Sbjct: 918 EDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKE 977 Query: 416 LHKTCS 421 KT S Sbjct: 978 DDKTLS 983 Score = 50.1 bits (118), Expect = 9e-06 Identities = 45/176 (25%), Positives = 82/176 (46%), Gaps = 18/176 (10%) Query: 246 IVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEG--RAGAGLGDGERKTN 303 +V+ + + +E TE + ++ E+ EEE+ E K+EEG A G+ E K+ Sbjct: 446 VVEKSEKETVIVEEQTE-ETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP 504 Query: 304 DKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD 363 +E K+A++ + K+ +KEE K +E ++ + +K ++ Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE------- 557 Query: 364 EGSVSESESESESGQAEEEKEEAEALKEKEK---PKEEEWEKPKDAAGLECKPRPL 416 ++S E++S + EE K AE +K EK P +EE + P +A E P+ Sbjct: 558 ----AKSPPEAKSPEKEEAKSPAE-VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV 608 Score = 49.7 bits (117), Expect = 1e-05 Identities = 42/152 (27%), Positives = 69/152 (45%), Gaps = 7/152 (4%) Query: 269 EQEEEEEQAGKPGEPSKK-EEGRAGAGLGDGERKTNDKDEKKEDGKQA---ENDSSNDDK 324 +++ ++E+A K P K EE + A E K K E+ ED K+ E ++ + Sbjct: 856 KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVE 915 Query: 325 TKKSEGDGDKEE--KKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE 382 K+ +K E KKE + +AK+ SK +K + + D + E + + Sbjct: 916 VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKA 975 Query: 383 KEEAEAL-KEKEKPKEEEWEKPKDAAGLECKP 413 KE+ + L KE KPK E+ EK + KP Sbjct: 976 KEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKP 1007 Score = 47.0 bits (110), Expect = 8e-05 Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 15/164 (9%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSK------KEEGRAGAGLGDGERKTNDKDEKKED 311 EGG E + E+E + A + P K KEE ++ A E K+ +K+E K Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPA-----EAKSPEKEEAKSP 541 Query: 312 GKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESE 371 AE S K+ E E K ++EAK ++ ++ + + + +E S +E Sbjct: 542 ---AEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK-SPAE 597 Query: 372 SESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRP 415 ++S KEEA++ E + P +EE + P + E P Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP 641 Score = 45.1 bits (105), Expect = 3e-04 Identities = 47/178 (26%), Positives = 82/178 (46%), Gaps = 16/178 (8%) Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQA-GKPGEP---SKKEEGRAGAGLG 296 +KA A K + K E + + + EE++E A KP E +KKEE + Sbjct: 845 EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVP 904 Query: 297 DGERKTNDKDEKKEDGKQAE---------NDSSNDDKTKKSEGDGDKEEKKEDSEKEAKK 347 E++ K E KED K E +D+ + +K +E EKK+ E++AKK Sbjct: 905 TPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKK 964 Query: 348 SSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE-EAEALKEKEKPKEEEWEKPK 404 +K + + D+ ++S+ S+ ++ +AE+ + + K EK E++ K K Sbjct: 965 PEEKPKTEAKAKE--DDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020 Score = 43.1 bits (100), Expect = 0.001 Identities = 33/139 (23%), Positives = 60/139 (43%), Gaps = 5/139 (3%) Query: 274 EEQAGKPGEPS--KKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331 +E+A P E +KEE ++ A + E+ K KE+ K S + + KS + Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKA---KSPAKEEAKSPPEAKSPEKEEAKSPAE 577 Query: 332 GDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKE 391 EK + KE KS + E + S +E++S + + E ++ ++ Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637 Query: 392 KEKPKEEEWEKPKDAAGLE 410 + P +EE + P+ A E Sbjct: 638 AKSPTKEEAKSPEKAKSPE 656 Score = 42.4 bits (98), Expect = 0.002 Identities = 36/139 (25%), Positives = 61/139 (43%), Gaps = 11/139 (7%) Query: 273 EEEQAGKPGEPSKKEEGRAGA---GLGDGERKTNDKDEKKE--DGKQAENDSSNDDKTKK 327 E+E+A P E E+ ++ A E K+ +K+E K + K E S + K Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593 Query: 328 SEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAE 387 S + EK + KE KS + E + S +E +S KEEA+ Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAE------AKSPVKEEAKSPAEVKSPEKAKSPTKEEAK 647 Query: 388 ALKEKEKPKEEEWEKPKDA 406 + ++ + P++EE + P+ A Sbjct: 648 SPEKAKSPEKEEAKSPEKA 666 Score = 40.8 bits (94), Expect = 0.006 Identities = 35/128 (27%), Positives = 56/128 (43%), Gaps = 5/128 (3%) Query: 275 EQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDK 334 E+A P + K +A + L + + + KKE+ K + + K E Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842 Query: 335 EEKKEDS--EKEAKKSSKKRN--RKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALK 390 EE+K + + E KK SKK +K + +E E ES + E +KEEAE K Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES-KVEAKKEEAEDKK 901 Query: 391 EKEKPKEE 398 + P++E Sbjct: 902 KVPTPEKE 909 Score = 40.4 bits (93), Expect = 0.007 Identities = 38/146 (26%), Positives = 67/146 (45%), Gaps = 9/146 (6%) Query: 274 EEQAGKPGEPSK--KEEGRAGAGLGDGER-KTNDKDEKK--EDGKQAENDSSNDDKTKKS 328 +E+A P E KEE ++ A + E+ K+ K+E K E K E + + + KS Sbjct: 609 KEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS 668 Query: 329 --EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE--KE 384 + + EK + K KS +K + E + S + E++S + + KE Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728 Query: 385 EAEALKEKEKPKEEEWEKPKDAAGLE 410 EA+ ++ + P +EE + P+ A E Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPE 754 Score = 39.3 bits (90), Expect = 0.016 Identities = 39/152 (25%), Positives = 66/152 (43%), Gaps = 3/152 (1%) Query: 255 IKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQ 314 +K E + + E+ + + + KEE R+ A + K+ K+E K K Sbjct: 740 VKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEK- 798 Query: 315 AENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES 374 A++ D K + E KEE K ++E K K + + ++E + Sbjct: 799 AKSPLKEDAKAPEKEIP-KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKK 857 Query: 375 ESGQAEEEKEEAEALKEKEKPKEEEWEKPKDA 406 +S + E K+EA K +EK KE EKPK++ Sbjct: 858 DSKKEEAPKKEAPKPKVEEK-KEPAVEKPKES 888 Score = 38.1 bits (87), Expect = 0.036 Identities = 38/139 (27%), Positives = 60/139 (43%), Gaps = 7/139 (5%) Query: 267 ILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326 + E+ + E+A P + K +A + + + E K+ +K + E K + S Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE-EAKSPEKAKSPEKAKTLDVKSPEAKTPA 770 Query: 327 KSEGDGDKE---EKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383 K E + EK + KE KS +K D E + + E E +S EEEK Sbjct: 771 KEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE-EVKSPVKEEEK 829 Query: 384 EEAEALKEKEKPKEEEWEK 402 + +K KE PK+ E EK Sbjct: 830 PQE--VKVKEPPKKAEEEK 846 Score = 37.4 bits (85), Expect = 0.061 Identities = 33/136 (24%), Positives = 64/136 (47%), Gaps = 11/136 (8%) Query: 272 EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQ-AENDSSNDDKTKKSEG 330 +EE ++ + +KEE ++ A + E+ K KE+ K AE S K+ E Sbjct: 555 KEEAKSPPEAKSPEKEEAKSPAEVKSPEKA---KSPAKEEAKSPAEAKSPEKAKSPVKEE 611 Query: 331 DGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALK 390 E K ++EAK ++ ++ + + S ++ E++S EKEEA++ + Sbjct: 612 AKSPAEAKSPVKEEAKSPAEVKSPEKA-------KSPTKEEAKSPEKAKSPEKEEAKSPE 664 Query: 391 EKEKPKEEEWEKPKDA 406 + + P + E + P+ A Sbjct: 665 KAKSPVKAEAKSPEKA 680 Score = 35.8 bits (81), Expect = 0.18 Identities = 32/138 (23%), Positives = 58/138 (42%), Gaps = 5/138 (3%) Query: 272 EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331 +EE ++ + + +KEE ++ + EK + +AE S K+ E + Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE-E 701 Query: 332 GDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALK- 390 EK + KE KS +K + E + S + E++S + + E+A+ L Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761 Query: 391 ---EKEKPKEEEWEKPKD 405 E + P +EE P D Sbjct: 762 KSPEAKTPAKEEARSPAD 779 Score = 35.8 bits (81), Expect = 0.18 Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 7/169 (4%) Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEE--EEQAGKPGEPSKKEEGRAGAGLGDG 298 +KA + VK + K + + + + E+ + +E+A P E +K E + Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP-EKAKSPEKAKTLDVKSP 764 Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358 E KT K+E + + + + K + + K KED++ K+ KK K Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824 Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAA 407 + E E + + +AEEEK A K +EK ++ E PK A Sbjct: 825 KE---EEKPQEVKVKEPPKKAEEEKAPATP-KTEEKKDSKKEEAPKKEA 869 Score = 34.3 bits (77), Expect = 0.52 Identities = 36/143 (25%), Positives = 59/143 (41%), Gaps = 6/143 (4%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEK--KEDGKQAENDSSNDDKTK 326 E+ + E+A P + K +A + + E K+ +K + KE+ K E S + Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKAKSPV-KAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 716 Query: 327 KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDE--GSVSESESESESGQAEEEKE 384 KS K+E E KS K K E ++ E+++ EE + Sbjct: 717 KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS 776 Query: 385 EAEALKEKEK-PKEEEWEKPKDA 406 A+ EK K P +EE + P+ A Sbjct: 777 PADKFPEKAKSPVKEEVKSPEKA 799 Score = 31.6 bits (70), Expect = 3.4 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Query: 338 KEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE--KEEAEALKEKEKP 395 K SE++ K K ++ +E V+E +E E +A+EE KEE +E+ + Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496 Query: 396 KEEEWEKP 403 EEE + P Sbjct: 497 GEEETKSP 504 >gi|27734775 hypothetical protein LOC286499 [Homo sapiens] Length = 248 Score = 56.2 bits (134), Expect = 1e-07 Identities = 42/162 (25%), Positives = 80/162 (49%), Gaps = 8/162 (4%) Query: 248 KMLDAAVIKMEGGTENDLRILEQEEEEEQAG--KPGEPSKKEEGRAGAGLGDGERKTNDK 305 K L+ + K+ G E+ + E++++ ++ S + + + D E+K + Sbjct: 71 KELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKR 130 Query: 306 DEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDS---EKEAKKSSKKRNRKHSGDDSF 362 +KK++ + SS + +S+ K++K +D EK+ + SKKR + + D Sbjct: 131 RKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPL 190 Query: 363 DEGSVSESESESESGQAEEEK--EEAEALKEKEKPKEEEWEK 402 S SES+ E E QA++++ EE E KEK K K+++ K Sbjct: 191 SSESSSESDYE-EDVQAKKKRRCEEREQAKEKVKKKKKKQHK 231 Score = 55.1 bits (131), Expect = 3e-07 Identities = 43/134 (32%), Positives = 61/134 (45%), Gaps = 18/134 (13%) Query: 279 KPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKK 338 K E KKE ++ L G ++ K E+K+ K+ SS+ S D Sbjct: 64 KMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSS------SSSSSDSSSSS 117 Query: 339 EDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEE 398 DSE E KK K+R +K + + S ESESES+ E++K+K+K K+E Sbjct: 118 SDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESK-----------ESVKKKKKSKDE 166 Query: 399 EWEKPKDAAGLECK 412 EK KD L K Sbjct: 167 T-EKEKDVRSLSKK 179 Score = 39.3 bits (90), Expect = 0.016 Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 6/104 (5%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAG--AGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326 E E E +++ K + SK E + L +K+ D+ +E+D D + K Sbjct: 148 ESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207 Query: 327 KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSES 370 K + E++E ++++ KK KK+++KHS GS +S Sbjct: 208 KKR----RCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 55.8 bits (133), Expect = 2e-07 Identities = 42/146 (28%), Positives = 68/146 (46%), Gaps = 6/146 (4%) Query: 271 EEEEEQAGKPGEPSKKEEGRAGA----GLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326 EE E+ E S+ EE + E K +EK+E+ + E + + Sbjct: 454 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 513 Query: 327 KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386 K+ KEE+ E E+E ++ ++ + D + + GS E SE E G+ EE + EA Sbjct: 514 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 573 Query: 387 EALKEKEKPKEEE--WEKPKDAAGLE 410 EA E+ + KEE+ EK ++ A E Sbjct: 574 EAEGEEAEAKEEKKVEEKSEEVATKE 599 Score = 52.4 bits (124), Expect = 2e-06 Identities = 40/125 (32%), Positives = 62/125 (49%), Gaps = 9/125 (7%) Query: 299 ERKTNDKDEKKEDGKQAENDS-SNDDKTKKSEGDGDKEEKKEDSEKE--AKKSSKKRN-- 353 E K D+ + E+ A + + K +K E +KEE+ E E+E AKKS K Sbjct: 459 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 518 Query: 354 --RKHSGDDSFDEGSVSESESE--SESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGL 409 ++ G+ +EG E E + ++S QAEE E E EKE+ ++EE E +A G Sbjct: 519 EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGE 578 Query: 410 ECKPR 414 E + + Sbjct: 579 EAEAK 583 Score = 52.4 bits (124), Expect = 2e-06 Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 12/160 (7%) Query: 258 EGGTENDLRILEQEEEEEQA--GKPGEPSKKEEGRAGAGLGDGERKTND--KDEKKEDGK 313 EG TE + E E +EE+ K E + KEE A A + E+ + K +E GK Sbjct: 568 EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK 627 Query: 314 QAENDSSNDDKTKKSEGDGDKEEK------KEDSEKEAKKSSKKRNRKHSGDDSFDEGSV 367 S ++K K EEK K E++ K K + + V Sbjct: 628 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 687 Query: 368 SESESESESGQAEEEKEEAEALKE--KEKPKEEEWEKPKD 405 E++S++E G+ E+++EE + +KE KE+ E++ EKPKD Sbjct: 688 EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKD 727 Score = 49.3 bits (116), Expect = 2e-05 Identities = 38/147 (25%), Positives = 73/147 (49%), Gaps = 16/147 (10%) Query: 264 DLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDD 323 +L + +EE++E A + E + EE A K + K+E+G++ E + ++ Sbjct: 479 ELAVSMKEEKKEAAEEKEEEPEAEEEEVAA--KKSPVKATAPEVKEEEGEKEEEEGQEEE 536 Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383 + E +G K ++ E+ E + SS+K ++ E +E+E+E E +A+EEK Sbjct: 537 ---EEEDEGAKSDQAEEGGSEKEGSSEK-------EEGEQEEGETEAEAEGEEAEAKEEK 586 Query: 384 EEAEALKE----KEKPKEEEWEKPKDA 406 + E +E +E + + EKP+ A Sbjct: 587 KVEEKSEEVATKEELVADAKVEKPEKA 613 Score = 47.8 bits (112), Expect = 5e-05 Identities = 41/164 (25%), Positives = 78/164 (47%), Gaps = 18/164 (10%) Query: 244 DAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTN 303 +A+ + + + M+ E E++EEE +A + +KK +A A E K Sbjct: 471 EALTAITEELAVSMK---EEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP----EVKEE 523 Query: 304 DKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD 363 + ++++E+G++ E + K+ ++E G EK+ SEKE + + + Sbjct: 524 EGEKEEEEGQEEEEEEDEGAKSDQAEEGGS--EKEGSSEKEEGEQEEGETEAEA------ 575 Query: 364 EGSVSESESESESGQAEEE---KEEAEALKEKEKPKEEEWEKPK 404 EG +E++ E + + EE KEE A + EKP++ + PK Sbjct: 576 EGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPK 619 Score = 47.8 bits (112), Expect = 5e-05 Identities = 50/166 (30%), Positives = 71/166 (42%), Gaps = 28/166 (16%) Query: 274 EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK----QAENDSSNDDKTKKSE 329 EE+A P S EE ++ A +G GE+K ++ E KE K + + + D KK Sbjct: 675 EEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKA 734 Query: 330 GDGDKEEK-----------KEDSEKEAKKSSK-----KRNRKHSGD-DSFDEGS-----V 367 KEE K EKE K+ K K K G+ S +EGS Sbjct: 735 ESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKG 794 Query: 368 SESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKP 413 S E + +G+ E ++E + KEK +EE EK GL+ P Sbjct: 795 SRKEDIAVNGEVEGKEEVEQETKEKGSGREE--EKGVVTNGLDLSP 838 Score = 45.1 bits (105), Expect = 3e-04 Identities = 39/155 (25%), Positives = 70/155 (45%), Gaps = 12/155 (7%) Query: 269 EQEEEEEQAGKPGEPSK-------KEEGRAGAGLGDGERKTND---KDEKKEDGKQAEND 318 E E EEE+ P K +EEG G E + D K ++ E+G + Sbjct: 498 EPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEG 557 Query: 319 SSNDDKTKKSEGDGDKEEKKEDSE-KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377 SS ++ ++ EG+ + E + E++E KE KK +K + ++ + V + E +++S Sbjct: 558 SSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE-KAKSP 616 Query: 378 QAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECK 412 + EE + P EE+ + P + +E K Sbjct: 617 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 651 Score = 41.2 bits (95), Expect = 0.004 Identities = 36/159 (22%), Positives = 73/159 (45%), Gaps = 4/159 (2%) Query: 246 IVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEG--RAGAGLGDGERKTN 303 +V + + + +E T+ + + L+QE+E+E+AG GE +EEG + G + N Sbjct: 746 VVTITKSVKVHLEKETKEEGKPLQQEKEKEKAG--GEGGSEEEGSDKGAKGSRKEDIAVN 803 Query: 304 DKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD 363 + E KE+ +Q + + + +K + D +K KS +K + + Sbjct: 804 GEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITS 863 Query: 364 EGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEK 402 EG ++ ++S ++ EE E E++ ++ EK Sbjct: 864 EGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEK 902 Score = 34.3 bits (77), Expect = 0.52 Identities = 43/195 (22%), Positives = 74/195 (37%), Gaps = 24/195 (12%) Query: 668 KLTPLLSVRESLSEEEAQKM---GRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGP 724 K +P+ + + EEE +K G+++ E+E E + +E G +K S +K +G Sbjct: 509 KKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEK---EGSSEKEEGE 565 Query: 725 --------EFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQIL 776 E + K +K+EE +EVA + DAK + K P P + Sbjct: 566 QEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEK 625 Query: 777 PPGLTPGLPYPH--QTPQGLMPYGQ------PRPPILGYGAGAV--RPAVPTGGPPYPHA 826 P P ++P P + P+ P+ G V P P P + Sbjct: 626 GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKS 685 Query: 827 PYGAGRGNYDAFRGQ 841 P + + +G+ Sbjct: 686 PVEEAKSKAEVGKGE 700 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 55.8 bits (133), Expect = 2e-07 Identities = 42/146 (28%), Positives = 68/146 (46%), Gaps = 6/146 (4%) Query: 271 EEEEEQAGKPGEPSKKEEGRAGA----GLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326 EE E+ E S+ EE + E K +EK+E+ + E + + Sbjct: 78 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 137 Query: 327 KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386 K+ KEE+ E E+E ++ ++ + D + + GS E SE E G+ EE + EA Sbjct: 138 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 197 Query: 387 EALKEKEKPKEEE--WEKPKDAAGLE 410 EA E+ + KEE+ EK ++ A E Sbjct: 198 EAEGEEAEAKEEKKVEEKSEEVATKE 223 Score = 52.4 bits (124), Expect = 2e-06 Identities = 40/125 (32%), Positives = 62/125 (49%), Gaps = 9/125 (7%) Query: 299 ERKTNDKDEKKEDGKQAENDS-SNDDKTKKSEGDGDKEEKKEDSEKE--AKKSSKKRN-- 353 E K D+ + E+ A + + K +K E +KEE+ E E+E AKKS K Sbjct: 83 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 142 Query: 354 --RKHSGDDSFDEGSVSESESE--SESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGL 409 ++ G+ +EG E E + ++S QAEE E E EKE+ ++EE E +A G Sbjct: 143 EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGE 202 Query: 410 ECKPR 414 E + + Sbjct: 203 EAEAK 207 Score = 52.4 bits (124), Expect = 2e-06 Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 12/160 (7%) Query: 258 EGGTENDLRILEQEEEEEQA--GKPGEPSKKEEGRAGAGLGDGERKTND--KDEKKEDGK 313 EG TE + E E +EE+ K E + KEE A A + E+ + K +E GK Sbjct: 192 EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK 251 Query: 314 QAENDSSNDDKTKKSEGDGDKEEK------KEDSEKEAKKSSKKRNRKHSGDDSFDEGSV 367 S ++K K EEK K E++ K K + + V Sbjct: 252 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 311 Query: 368 SESESESESGQAEEEKEEAEALKE--KEKPKEEEWEKPKD 405 E++S++E G+ E+++EE + +KE KE+ E++ EKPKD Sbjct: 312 EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKD 351 Score = 49.3 bits (116), Expect = 2e-05 Identities = 38/147 (25%), Positives = 73/147 (49%), Gaps = 16/147 (10%) Query: 264 DLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDD 323 +L + +EE++E A + E + EE A K + K+E+G++ E + ++ Sbjct: 103 ELAVSMKEEKKEAAEEKEEEPEAEEEEVAA--KKSPVKATAPEVKEEEGEKEEEEGQEEE 160 Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383 + E +G K ++ E+ E + SS+K ++ E +E+E+E E +A+EEK Sbjct: 161 ---EEEDEGAKSDQAEEGGSEKEGSSEK-------EEGEQEEGETEAEAEGEEAEAKEEK 210 Query: 384 EEAEALKE----KEKPKEEEWEKPKDA 406 + E +E +E + + EKP+ A Sbjct: 211 KVEEKSEEVATKEELVADAKVEKPEKA 237 Score = 47.8 bits (112), Expect = 5e-05 Identities = 41/164 (25%), Positives = 78/164 (47%), Gaps = 18/164 (10%) Query: 244 DAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTN 303 +A+ + + + M+ E E++EEE +A + +KK +A A E K Sbjct: 95 EALTAITEELAVSMK---EEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP----EVKEE 147 Query: 304 DKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD 363 + ++++E+G++ E + K+ ++E G EK+ SEKE + + + Sbjct: 148 EGEKEEEEGQEEEEEEDEGAKSDQAEEGGS--EKEGSSEKEEGEQEEGETEAEA------ 199 Query: 364 EGSVSESESESESGQAEEE---KEEAEALKEKEKPKEEEWEKPK 404 EG +E++ E + + EE KEE A + EKP++ + PK Sbjct: 200 EGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPK 243 Score = 47.8 bits (112), Expect = 5e-05 Identities = 50/166 (30%), Positives = 71/166 (42%), Gaps = 28/166 (16%) Query: 274 EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK----QAENDSSNDDKTKKSE 329 EE+A P S EE ++ A +G GE+K ++ E KE K + + + D KK Sbjct: 299 EEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKA 358 Query: 330 GDGDKEEK-----------KEDSEKEAKKSSK-----KRNRKHSGD-DSFDEGS-----V 367 KEE K EKE K+ K K K G+ S +EGS Sbjct: 359 ESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKG 418 Query: 368 SESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKP 413 S E + +G+ E ++E + KEK +EE EK GL+ P Sbjct: 419 SRKEDIAVNGEVEGKEEVEQETKEKGSGREE--EKGVVTNGLDLSP 462 Score = 45.1 bits (105), Expect = 3e-04 Identities = 39/155 (25%), Positives = 70/155 (45%), Gaps = 12/155 (7%) Query: 269 EQEEEEEQAGKPGEPSK-------KEEGRAGAGLGDGERKTND---KDEKKEDGKQAEND 318 E E EEE+ P K +EEG G E + D K ++ E+G + Sbjct: 122 EPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEG 181 Query: 319 SSNDDKTKKSEGDGDKEEKKEDSE-KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377 SS ++ ++ EG+ + E + E++E KE KK +K + ++ + V + E +++S Sbjct: 182 SSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE-KAKSP 240 Query: 378 QAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECK 412 + EE + P EE+ + P + +E K Sbjct: 241 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 275 Score = 41.2 bits (95), Expect = 0.004 Identities = 36/159 (22%), Positives = 73/159 (45%), Gaps = 4/159 (2%) Query: 246 IVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEG--RAGAGLGDGERKTN 303 +V + + + +E T+ + + L+QE+E+E+AG GE +EEG + G + N Sbjct: 370 VVTITKSVKVHLEKETKEEGKPLQQEKEKEKAG--GEGGSEEEGSDKGAKGSRKEDIAVN 427 Query: 304 DKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD 363 + E KE+ +Q + + + +K + D +K KS +K + + Sbjct: 428 GEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITS 487 Query: 364 EGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEK 402 EG ++ ++S ++ EE E E++ ++ EK Sbjct: 488 EGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEK 526 Score = 34.3 bits (77), Expect = 0.52 Identities = 43/195 (22%), Positives = 74/195 (37%), Gaps = 24/195 (12%) Query: 668 KLTPLLSVRESLSEEEAQKM---GRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGP 724 K +P+ + + EEE +K G+++ E+E E + +E G +K S +K +G Sbjct: 133 KKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEK---EGSSEKEEGE 189 Query: 725 --------EFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQIL 776 E + K +K+EE +EVA + DAK + K P P + Sbjct: 190 QEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEK 249 Query: 777 PPGLTPGLPYPH--QTPQGLMPYGQ------PRPPILGYGAGAV--RPAVPTGGPPYPHA 826 P P ++P P + P+ P+ G V P P P + Sbjct: 250 GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKS 309 Query: 827 PYGAGRGNYDAFRGQ 841 P + + +G+ Sbjct: 310 PVEEAKSKAEVGKGE 324 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 55.5 bits (132), Expect = 2e-07 Identities = 46/186 (24%), Positives = 79/186 (42%), Gaps = 9/186 (4%) Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315 K + E D E EE++E + + + +A A E + ++ DE ED Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201 Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375 E D S ++ + + G K K + AK ++ + + +D D+ + + + E Sbjct: 202 EEDDSEEEAMETTPAKGKKAAKVVPVK--AKNVAEDEDEEEDDEDEDDDDDEDDEDDDDE 259 Query: 376 SGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT-----CSLFMRNIAPN 430 EEE+EE E KE P + + E K A E K + + T +LF+ N+ N Sbjct: 260 DD--EEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFN 317 Query: 431 ISRAEI 436 S E+ Sbjct: 318 KSAPEL 323 Score = 53.1 bits (126), Expect = 1e-06 Identities = 36/122 (29%), Positives = 57/122 (46%), Gaps = 7/122 (5%) Query: 275 EQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDK 334 ++ PG+ G+ GA + K N K+ KKED + E+D S +D+ E D D+ Sbjct: 109 KKGATPGKALVATPGKKGAAIPAKGAK-NGKNAKKEDSDEEEDDDSEEDE----EDDEDE 163 Query: 335 EEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEK 394 +E +++ E A K++ DD DE E + + E +EEE E K K+ Sbjct: 164 DEDEDEIEPAAMKAAAAAPASEDEDDEDDED--DEDDDDDEEDDSEEEAMETTPAKGKKA 221 Query: 395 PK 396 K Sbjct: 222 AK 223 Score = 30.0 bits (66), Expect = 9.8 Identities = 28/120 (23%), Positives = 52/120 (43%), Gaps = 9/120 (7%) Query: 289 GRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKS 348 G+ GA G T K K A+N + KK + D EE+ +DSE++ + Sbjct: 108 GKKGATPGKALVATPGKKGAAIPAKGAKNGKN----AKKEDSD---EEEDDDSEEDEEDD 160 Query: 349 SKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAG 408 + + + + + + + SE E + +E+ E+ + ++E EEE + A G Sbjct: 161 EDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDD--DDEEDDSEEEAMETTPAKG 218 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 55.5 bits (132), Expect = 2e-07 Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 9/164 (5%) Query: 251 DAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE 310 + A + EG T+ + ++E +E EE+A E + E +GE + +D Sbjct: 1944 EEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDV--- 2000 Query: 311 DGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSES 370 + +AE + ++ + E DG + + K SE E + + +K GD + V Sbjct: 2001 EAPEAEGEMQEAEEEAQPESDGVEAQPK--SEGEEAQEVEGETQKTEGDAQPESDGVEAP 2058 Query: 371 ESESESGQAEEEKEEAEALKEKEK----PKEEEWEKPKDAAGLE 410 E+E E+ +AE E +EAE E +E E E ++ G+E Sbjct: 2059 EAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVE 2102 Score = 47.0 bits (110), Expect = 8e-05 Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 9/142 (6%) Query: 274 EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGD 333 +E+ GK + E AG+ LG+ E++ E+ E G Q N + GD D Sbjct: 1770 QEREGK----THNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQD 1825 Query: 334 KEEKKEDSEKEAKKSSKKRNRKHSGDDSFD-EGSVSESES----ESESGQAEEEKEEAEA 388 + EA ++ + + G ++ + EG E+E ESE +A E + EA+ Sbjct: 1826 PGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQP 1885 Query: 389 LKEKEKPKEEEWEKPKDAAGLE 410 E + E EWE ++ G E Sbjct: 1886 ESEDVETPEAEWEVQPESEGAE 1907 Score = 46.6 bits (109), Expect = 1e-04 Identities = 38/164 (23%), Positives = 81/164 (49%), Gaps = 11/164 (6%) Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK-Q 314 ++EG T+ + E + +A + E +++ EG G+ ++ D D ++ +G+ Q Sbjct: 2036 EVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQ 2095 Query: 315 AENDSSN----DDKTKKSEG----DGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGS 366 E++ + + +K+EG + + E + E EA ++ + + G ++ D + Sbjct: 2096 PESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQD--A 2153 Query: 367 VSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLE 410 E++ ESE +A+E +EEA+ E + E E E ++ G+E Sbjct: 2154 EGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIE 2197 Score = 44.3 bits (103), Expect = 5e-04 Identities = 30/147 (20%), Positives = 65/147 (44%), Gaps = 1/147 (0%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328 E + E E P + + GA + E++ + E E + D + + Sbjct: 1882 EAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQ 1941 Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD-EGSVSESESESESGQAEEEKEEAE 387 E + +E + ++ E++ + + + +S D E E E++ G+A+ E E+ E Sbjct: 1942 EAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVE 2001 Query: 388 ALKEKEKPKEEEWEKPKDAAGLECKPR 414 A + + + +E E E ++ G+E +P+ Sbjct: 2002 APEAEGEMQEAEEEAQPESDGVEAQPK 2028 Score = 43.5 bits (101), Expect = 9e-04 Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 14/176 (7%) Query: 251 DAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGD---GERKTN-DKD 306 DA + EG T N E E + G + E G G+G D GE D+D Sbjct: 1766 DAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQD 1825 Query: 307 EKKEDGKQA-ENDSSNDDKTKKSEG------DGDKEEKKEDSEKEAKKSSKKRNRKHSGD 359 + DG + E + + +SEG +GD +E + +++ E++ + Sbjct: 1826 PGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQP 1885 Query: 360 DSFDEGSVS---ESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECK 412 +S D + E + ESE +A E ++EA+ E + E E E ++ G E + Sbjct: 1886 ESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQ 1941 Score = 43.1 bits (100), Expect = 0.001 Identities = 38/164 (23%), Positives = 76/164 (46%), Gaps = 15/164 (9%) Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA----EN 317 E +++ E+E + E G +P K EG + +KT + + DG +A E Sbjct: 2006 EGEMQEAEEEAQPESDGVEAQP--KSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEE 2063 Query: 318 DSSNDDKTKKSEGDGDKEEKKEDSEK---EAKKSSKKRNRKHS-GDDSFDEG-----SVS 368 + + +++EG+ E + D+++ EA+ S+ + G+ EG + Sbjct: 2064 AQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEG 2123 Query: 369 ESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECK 412 E++ ESE +A E + EA+ E + ++ E E ++ G+E + Sbjct: 2124 EAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQ 2167 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/147 (21%), Positives = 64/147 (43%), Gaps = 4/147 (2%) Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKK 327 +E E E +A E + E A +GE + +D + + + S D +T + Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPE 1894 Query: 328 SEGDGDKEEK---KEDSEKEAKKSSKKRNRKHS-GDDSFDEGSVSESESESESGQAEEEK 383 +E + E + ++EKEA+ ++ + G+D + E+E + +AE + Sbjct: 1895 AEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQT 1954 Query: 384 EEAEALKEKEKPKEEEWEKPKDAAGLE 410 + + E ++ +EE + +D LE Sbjct: 1955 QPESEVIESQEAEEEAQPESEDVEALE 1981 Score = 40.4 bits (93), Expect = 0.007 Identities = 39/186 (20%), Positives = 85/186 (45%), Gaps = 17/186 (9%) Query: 239 DIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA-----GA 293 D++ +A +M +A + E E+D + + E E+A + ++K EG A G Sbjct: 1999 DVEAPEAEGEMQEA---EEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGV 2055 Query: 294 GLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEE---KKEDSEKEAKKSSK 350 + E + + + + ++ + + S D +++EG+ E + ++E EA+K+ Sbjct: 2056 EAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEG 2115 Query: 351 KRNRKHSGDDSFDEGSV------SESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPK 404 + G+ + + E++ ESE +A++ + EA+ E + +E E E Sbjct: 2116 IEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQP 2175 Query: 405 DAAGLE 410 + G+E Sbjct: 2176 ELEGVE 2181 Score = 40.4 bits (93), Expect = 0.007 Identities = 39/154 (25%), Positives = 69/154 (44%), Gaps = 11/154 (7%) Query: 269 EQEEEEEQAGKPG---EPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA----ENDSSN 321 E +E EE+A E K EG + +KT + + DG +A E Sbjct: 2008 EMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEA 2067 Query: 322 DDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSES-ESESESGQAE 380 + + +++EG+ E + D++ EA+ ++ + ++ E +E E+ G+A+ Sbjct: 2068 EGEVQEAEGEAHPESEDVDAQ-EAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQ 2126 Query: 381 EEKEEAEALK-EKEKPKEEEWEKPKDAAGLECKP 413 E E EA + E E E E + +DA G E +P Sbjct: 2127 PESEGIEAPEAEGEAQPESEGVEAQDAEG-EAQP 2159 Score = 39.7 bits (91), Expect = 0.012 Identities = 36/172 (20%), Positives = 78/172 (45%), Gaps = 7/172 (4%) Query: 238 LDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGD 297 ++ +A+ + + V + EG + ++ +E E +A E + E A + Sbjct: 2055 VEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAE 2114 Query: 298 GERKTNDKDEKKEDGKQAENDSSNDDKTKKSEG----DGDKEEKKEDSEKEAKKSSKKRN 353 G + E + + + E + + +SEG D + E + E EA+++ ++ Sbjct: 2115 GIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQ 2174 Query: 354 RKHSGDDSFDEGSVSESESESESGQAEEEKEEAE-ALKEKEKPKEEEWEKPK 404 + G ++ + + E++ ESE +A E + EA+ L+ E P+ EE +P+ Sbjct: 2175 PELEGVEAPE--AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPE 2224 Score = 38.9 bits (89), Expect = 0.021 Identities = 37/162 (22%), Positives = 67/162 (41%), Gaps = 6/162 (3%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317 E + ++++ E +E E G E + EE + GL + + + E + +G+Q E Sbjct: 1294 ENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEE 1353 Query: 318 DSSNDDKTKKSEGDGDK----EEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESE 373 + + EG ++ EE KE E + + + K G +EGSV E Sbjct: 1354 AQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLP--EEGSVHGQELS 1411 Query: 374 SESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRP 415 S + +E + ++E+E + +P A G E P Sbjct: 1412 EASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEP 1453 Score = 37.4 bits (85), Expect = 0.061 Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 9/139 (6%) Query: 273 EEEQAGKPGEPSKKE-EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331 E +A K +P + E G + E + + E +E ++AE + + + +S+ + Sbjct: 1907 EAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ-E 1965 Query: 332 GDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE------E 385 ++E + E + EA + + ++ G+ + V E+E E +AEEE + E Sbjct: 1966 AEEEAQPESEDVEALEVEVE-TQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVE 2024 Query: 386 AEALKEKEKPKEEEWEKPK 404 A+ E E+ +E E E K Sbjct: 2025 AQPKSEGEEAQEVEGETQK 2043 Score = 35.0 bits (79), Expect = 0.30 Identities = 29/145 (20%), Positives = 66/145 (45%), Gaps = 15/145 (10%) Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGA-GLGDGERKTNDKDEKKEDGK-QAENDSSNDDKT 325 LE E E+E + E + EE A G E + + E +E+ + ++E+ + + + Sbjct: 1925 LETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEV 1984 Query: 326 KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385 + E +G+ + + ED E + + + E++ ES+ +A+ + E Sbjct: 1985 ETQEAEGEAQPESEDVEAPEAEGEMQEAEE-------------EAQPESDGVEAQPKSEG 2031 Query: 386 AEALKEKEKPKEEEWEKPKDAAGLE 410 EA + + + ++ E + ++ G+E Sbjct: 2032 EEAQEVEGETQKTEGDAQPESDGVE 2056 Score = 33.9 bits (76), Expect = 0.68 Identities = 41/164 (25%), Positives = 62/164 (37%), Gaps = 14/164 (8%) Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEE--GRAGAGLGDGERKTNDKDEKKEDGK 313 K E G + + LE+ +E E G+ E ++ EE G GL + + + E E G Sbjct: 1326 KTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGL 1385 Query: 314 QAEN-DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES 372 Q E + ++ EG +E E S + K S + DD E + + Sbjct: 1386 QGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQE--------DDPVQEEEAGRASA 1437 Query: 373 ESESGQAE---EEKEEAEALKEKEKPKEEEWEKPKDAAGLECKP 413 +E AE E E L E + E + GLE P Sbjct: 1438 SAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPP 1481 Score = 33.9 bits (76), Expect = 0.68 Identities = 30/141 (21%), Positives = 54/141 (38%), Gaps = 26/141 (18%) Query: 287 EEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAK 346 +EG G G +R DKD K + + + KT SE E + + E E Sbjct: 1741 DEGEDGEG---SQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGI 1797 Query: 347 KSSKKRNRKHSGDDSFDEGSVS-----------------------ESESESESGQAEEEK 383 + + SG + +G + E++ ESE +A E + Sbjct: 1798 SERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAE 1857 Query: 384 EEAEALKEKEKPKEEEWEKPK 404 +A+ + + +P+ E+ E P+ Sbjct: 1858 GDAQEAEGEAQPESEDVEAPE 1878 Score = 30.4 bits (67), Expect = 7.5 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 11/129 (8%) Query: 291 AGAGLGDGERKTNDKDEKKEDGKQAEN-DSSNDDKTKKSEGDG---DKEEKKEDSEKEAK 346 A GLG G + DE EDG+ ++ + D K ++EGD ++E K +SE A Sbjct: 1726 AEGGLGPGLSQGPGVDEG-EDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAG 1784 Query: 347 KSSKKRNRKHSG----DDSFDEGSVSESESESESGQ-AEEEKEEAEALKEKEKPKEEEWE 401 + ++ G ++ +GS E + E+ +++ +++ + E P E E E Sbjct: 1785 SELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAP-EAEGE 1843 Query: 402 KPKDAAGLE 410 ++ G+E Sbjct: 1844 AQPESEGVE 1852 >gi|83921609 hypothetical protein LOC127254 [Homo sapiens] Length = 1530 Score = 55.1 bits (131), Expect = 3e-07 Identities = 47/184 (25%), Positives = 85/184 (46%), Gaps = 26/184 (14%) Query: 257 MEGGTENDLRILEQEE----EEEQAGKPGEPSKKEEGRAGAGL-GDGERKTNDKDEKKED 311 +E EN L+ +E+ EE+Q K EEG+A + G + +DK + + Sbjct: 486 LEDDQENTLKYEYEEDFEVDEEKQGEK-----SNEEGQADVQMNGIPQSPLDDKKDNLDP 540 Query: 312 GKQAENDSSNDDKTK---KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHS-GDDSFDEGSV 367 K++E S + K E DG E + E+ +++ K +S +R H DS DE +V Sbjct: 541 EKESETSSQKAPDARDNVKDENDGCSESELEEDKQDMKTASSTSSRSHPYSSDSEDESAV 600 Query: 368 SESESESESGQAEE-EKEEAEALKEKEKPKE-----------EEWEKPKDAAGLECKPRP 415 + E+ ++S E + ++ L E +KP++ E ++ A +E KP P Sbjct: 601 GDREAHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEITKADVETKPMP 660 Query: 416 LHKT 419 + ++ Sbjct: 661 IDES 664 Score = 36.6 bits (83), Expect = 0.10 Identities = 43/187 (22%), Positives = 71/187 (37%), Gaps = 33/187 (17%) Query: 247 VKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEP--------SKKEEGRAGAGLGDG 298 V L A EG E + + + E EE+A E SK+E+G A LG G Sbjct: 919 VAALREAATSEEGEAEGGVAVSDVGESEEEASIDLEDTGPMEDTASKREDGSEEAILG-G 977 Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEK---------KEDSEKEAKKSS 349 E ++ E + + + ++ +G EE KED E E + Sbjct: 978 EEPAKERKEVMRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAFLCKEDVEGEEMVTE 1037 Query: 350 KKRNRKHSGDDSFDEG---------------SVSESESESESGQAEEEKEEAEALKEKEK 394 + NR+ + + S+ +++SE E ++ +A KE++K Sbjct: 1038 AEANREDDRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQK 1097 Query: 395 PKEEEWE 401 K EE E Sbjct: 1098 LKAEEGE 1104 Score = 32.3 bits (72), Expect = 2.0 Identities = 42/174 (24%), Positives = 68/174 (39%), Gaps = 21/174 (12%) Query: 241 DKADAIVKMLDAAVIKMEGGT-ENDLRILEQEEEEEQAGKP--GEPSKKEEGRAGAGLGD 297 D+ + + K LD A + + + LR + E EE E + KEE + A G+ Sbjct: 1045 DRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGE 1104 Query: 298 GERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEA-----------K 346 E + ++E K + +D+ N+ + SE + EDS KE + Sbjct: 1105 TETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGEDSLKETVVPIFEATPGFE 1164 Query: 347 KSSKKRN--RKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEE 398 KS + RK G + +SE+ + E E ALKE + E Sbjct: 1165 KSLENITALRKEGGGE-----RLSEARDTEHKDREELSSRENRALKEGHRQDGE 1213 Score = 30.8 bits (68), Expect = 5.7 Identities = 33/151 (21%), Positives = 59/151 (39%), Gaps = 16/151 (10%) Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317 +GG + LR E EE+ P E+ R E ++ E++ED + Sbjct: 1261 QGGVDVVLRTQEAVAEED-------PIMAEKFR--------EEAVDEDPEEEEDKECTLE 1305 Query: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377 + D+ + +GD + E + +E H G ++ E + E E + S Sbjct: 1306 TEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGET-AETAAEEREVLAGSE 1364 Query: 378 QAEEEKEEAEALKEKEKPKEEEWEKPKDAAG 408 AEE+ +A + +EE W + + G Sbjct: 1365 TAEEKTIANKASSFSDVAEEETWHQQDELVG 1395 >gi|168229156 NFKB activating protein [Homo sapiens] Length = 415 Score = 54.7 bits (130), Expect = 4e-07 Identities = 36/127 (28%), Positives = 62/127 (48%), Gaps = 8/127 (6%) Query: 270 QEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE 329 +EE+++++ + E SKK + + +RK E + +E DSS++D ++++ Sbjct: 179 EEEKKKKSSRSKERSKKRRKKKSS-----KRKHKKYSEDSDSDSDSETDSSDEDNKRRAK 233 Query: 330 GDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEAL 389 KE+KK+ K+ KK K++RK S D S E S+ E + + EE L Sbjct: 234 KAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKE---SQEEFLENPWKDRTKAEEPSDL 290 Query: 390 KEKEKPK 396 E PK Sbjct: 291 IGPEAPK 297 Score = 53.9 bits (128), Expect = 6e-07 Identities = 45/152 (29%), Positives = 75/152 (49%), Gaps = 17/152 (11%) Query: 260 GTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTN---DKDE----KKEDG 312 G++ L +E EE + ++ G GA G N D DE + E+ Sbjct: 109 GSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEP 168 Query: 313 KQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES 372 K++ +S ++ KK + KE K+ + KKSSK++++K+S E S S+S+S Sbjct: 169 KKSTTSASTSEEEKKKKSSRSKERSKK---RRKKKSSKRKHKKYS------EDSDSDSDS 219 Query: 373 ESESGQAEEEKEEAEALKEKEKPKEEEWEKPK 404 E++S E+ K A+ K+KEK K+ +K K Sbjct: 220 ETDSSD-EDNKRRAKKAKKKEKKKKHRSKKYK 250 Score = 52.8 bits (125), Expect = 1e-06 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 8/144 (5%) Query: 272 EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE-- 329 E + P E + ++ A + E+K K+ K+ + SS K SE Sbjct: 154 EPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDS 213 Query: 330 ---GDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386 D + + ED+++ AKK+ KK +K + + +S ES ++E +EE Sbjct: 214 DSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEF 273 Query: 387 EALKEKEKPKEEEWEKPKDAAGLE 410 K++ K EE P D G E Sbjct: 274 LENPWKDRTKAEE---PSDLIGPE 294 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 54.7 bits (130), Expect = 4e-07 Identities = 56/240 (23%), Positives = 98/240 (40%), Gaps = 30/240 (12%) Query: 161 DSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNR 220 D +TE+ + D R+ +D KD++ +K +P+ +A+ A + Sbjct: 325 DVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDS 384 Query: 221 LRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKP 280 L K D K DA I +E++L E +++E++ K Sbjct: 385 RN--------------LKKASKNDD--KKKDAKKITFSTDSESELESKESQKDEKKDKKD 428 Query: 281 GEPSKKEEGRAGAGLGDGERKTNDKDEK-KEDGKQAENDSSNDDKTK-------KSEGDG 332 + K+ + D + + +K K+D K+ + DS DDK K +E + Sbjct: 429 SKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMES 488 Query: 333 DKEEKKEDSEKEAKKSSKK------RNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386 D E KK+ + KK SKK R S D FDE S + ++ ++ ++ E EE+ Sbjct: 489 DLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEES 548 Score = 53.9 bits (128), Expect = 6e-07 Identities = 32/140 (22%), Positives = 66/140 (47%), Gaps = 2/140 (1%) Query: 265 LRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDK 324 LR Q + + K + +KK+ + D E + D + K+D K+ + + DDK Sbjct: 265 LRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAE--SEDSKDAKKDSKKVKKNVKKDDK 322 Query: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE 384 K + D + + + K+ +K +KK +K DD + +++ESG A++ + Sbjct: 323 KKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARN 382 Query: 385 EAEALKEKEKPKEEEWEKPK 404 ++ LK+ K +++ + K Sbjct: 383 DSRNLKKASKNDDKKKDAKK 402 Score = 52.4 bits (124), Expect = 2e-06 Identities = 43/163 (26%), Positives = 80/163 (49%), Gaps = 17/163 (10%) Query: 261 TENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSS 320 T+ D + L+++++++ K E + E G D + ND K K ++ND Sbjct: 347 TKKDKKKLKKDDKKKDTKKYPESTDTESG-------DAKDARNDSRNLK---KASKNDDK 396 Query: 321 NDDKTK-----KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375 D K SE + + +E ++D EK+ KK SK N+K +D + SE + +S+ Sbjct: 397 KKDAKKITFSTDSESELESKESQKD-EKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSK 455 Query: 376 SGQAEEEKEEAEALK-EKEKPKEEEWEKPKDAAGLECKPRPLH 417 G+ +E+K + ++ K +K+K ++ E + + LE K H Sbjct: 456 KGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH 498 Score = 51.2 bits (121), Expect = 4e-06 Identities = 38/148 (25%), Positives = 69/148 (46%), Gaps = 8/148 (5%) Query: 263 NDLRILEQEEEEEQAGKPGEP---SKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS 319 ND R L++ + + K + S E + + K + KD K ++ K +ND Sbjct: 382 NDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDE 441 Query: 320 SNDDKTKKSEGD---GDKEEKK--EDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES 374 + D + +GD G K+EKK +DS+K+ KK K+N + + +S E + S+ Sbjct: 442 ESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKE 501 Query: 375 ESGQAEEEKEEAEALKEKEKPKEEEWEK 402 + G ++ K++A E + +E K Sbjct: 502 KKGSKKDIKKDARKDTESTDAEFDESSK 529 Score = 50.8 bits (120), Expect = 5e-06 Identities = 38/147 (25%), Positives = 68/147 (46%), Gaps = 26/147 (17%) Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS---SNDDKT 325 E E E +++ K + KK+ KT++K K D + + DS + K Sbjct: 410 ESELESKESQKDEKKDKKDS------------KTDNKKSVKNDEESTDADSEPKGDSKKG 457 Query: 326 KKSEGDGDKEEKKEDSEKEAKKSSK----------KRNRKHSGDDSFDEGSV-SESESES 374 KK E G K+ KK+D +K+AKK+++ K+++KHS + + + ++ ++ Sbjct: 458 KKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDT 517 Query: 375 ESGQAEEEKEEAEALKEKEKPKEEEWE 401 ES AE ++ K K K + E Sbjct: 518 ESTDAEFDESSKTGFKTSTKIKGSDTE 544 Score = 45.8 bits (107), Expect = 2e-04 Identities = 36/158 (22%), Positives = 75/158 (47%), Gaps = 27/158 (17%) Query: 271 EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQ------AENDSSNDDK 324 +++ ++ K ++ E+ + +K KD+KK+D K+ AE+ S D++ Sbjct: 285 KKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDER 344 Query: 325 --TKKSEGDGDKEEKKEDSE-------------KEAKKSSKKRNRKHSGDDSFDE----- 364 TKK + K++KK+D++ K+A+ S+ + DD + Sbjct: 345 KDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKIT 404 Query: 365 -GSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWE 401 + SESE ES+ Q +E+K++ ++ + +K + + E Sbjct: 405 FSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEE 442 Score = 42.0 bits (97), Expect = 0.002 Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 22/147 (14%) Query: 279 KPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSN---DDKTKKSEGDGDKE 335 K E K ++ + G L KD KK+ G A N S ++KTK+ + + DK Sbjct: 111 KKAEYKKSKDEKGGTPL--------KKDSKKKGGSYATNPESKQIVEEKTKR-QNEADKT 161 Query: 336 EKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE-EAEALKEKEK 394 K E E K SK + + +S + +VS++ S+ + ++ K+ E L K Sbjct: 162 PLKSSHENEQSKKSK--SSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNN 219 Query: 395 PKEEEWEKPKDAAGLECKPRPLHKTCS 421 PK KD + P+ + CS Sbjct: 220 PK-------KDLKRSKTSNDPISEICS 239 Score = 30.0 bits (66), Expect = 9.8 Identities = 33/143 (23%), Positives = 61/143 (42%), Gaps = 19/143 (13%) Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKK-EDSEKEAKKSSKKRNRKHS 357 E+K + KD KK+ K E+ + D++ K+ G K K + S+ E+++S K K Sbjct: 501 EKKGSKKDIKKDARKDTESTDAEFDESSKT---GFKTSTKIKGSDTESEESLYKPGAKKK 557 Query: 358 GDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLH 417 D+S +G+ + S+ E E + + K+ E+ EK + +P Sbjct: 558 IDES--DGTSANSKMEG------LESKRGFRMSSKKTTFNEKGEKASTGRVPPSREKPPL 609 Query: 418 KTCSLFMRNIAPNISRAEIISLC 440 C P++ ++ LC Sbjct: 610 PACE-------PSLPSPKVRRLC 625 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.135 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 43,605,221 Number of Sequences: 37866 Number of extensions: 2709115 Number of successful extensions: 43633 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 749 Number of HSP's successfully gapped in prelim test: 1223 Number of HSP's that attempted gapping in prelim test: 15573 Number of HSP's gapped (non-prelim): 15294 length of query: 875 length of database: 18,247,518 effective HSP length: 111 effective length of query: 764 effective length of database: 14,044,392 effective search space: 10729915488 effective search space used: 10729915488 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.