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Search of human proteins with 190194355
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190194355 p90 autoantigen [Homo sapiens]
(905 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190194355 p90 autoantigen [Homo sapiens] 1744 0.0
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 74 8e-13
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 73 1e-12
gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [... 72 2e-12
gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2 [... 72 2e-12
gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3 [... 72 2e-12
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 70 7e-12
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 70 7e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 70 7e-12
gi|118498356 kinectin 1 isoform a [Homo sapiens] 70 1e-11
gi|33620775 kinectin 1 isoform a [Homo sapiens] 70 1e-11
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 69 3e-11
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 69 3e-11
gi|118498368 kinectin 1 isoform c [Homo sapiens] 67 6e-11
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 67 6e-11
gi|34577114 cytomatrix protein p110 [Homo sapiens] 67 8e-11
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 67 1e-10
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 67 1e-10
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 66 1e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 66 2e-10
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 66 2e-10
gi|118498362 kinectin 1 isoform b [Homo sapiens] 65 2e-10
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 65 2e-10
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 65 2e-10
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 65 2e-10
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 65 2e-10
gi|7705415 hook homolog 1 [Homo sapiens] 65 2e-10
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 65 2e-10
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 65 3e-10
gi|55770834 centromere protein F [Homo sapiens] 65 3e-10
>gi|190194355 p90 autoantigen [Homo sapiens]
Length = 905
Score = 1744 bits (4516), Expect = 0.0
Identities = 905/905 (100%), Positives = 905/905 (100%)
Query: 1 MDSTACLKSLLLTVSQYKAVKSEANATQLLRHLEVISGQKLTRLFTSNQILTSECLSCLV 60
MDSTACLKSLLLTVSQYKAVKSEANATQLLRHLEVISGQKLTRLFTSNQILTSECLSCLV
Sbjct: 1 MDSTACLKSLLLTVSQYKAVKSEANATQLLRHLEVISGQKLTRLFTSNQILTSECLSCLV 60
Query: 61 ELLEDPNISASLILSIIGLLSQLAVDIETRDCLQNTYNLNSVLAGVVCRSSHTDSVFLQC 120
ELLEDPNISASLILSIIGLLSQLAVDIETRDCLQNTYNLNSVLAGVVCRSSHTDSVFLQC
Sbjct: 61 ELLEDPNISASLILSIIGLLSQLAVDIETRDCLQNTYNLNSVLAGVVCRSSHTDSVFLQC 120
Query: 121 IQLLQKLTYNVKIFYSGANIDELITFLIDHIQSSEDELKMPCLGLLANLCRHNLSVQTHI 180
IQLLQKLTYNVKIFYSGANIDELITFLIDHIQSSEDELKMPCLGLLANLCRHNLSVQTHI
Sbjct: 121 IQLLQKLTYNVKIFYSGANIDELITFLIDHIQSSEDELKMPCLGLLANLCRHNLSVQTHI 180
Query: 181 KTLSNVKSFYRTLITLLAHSSLTVVVFALSILSSLTLNEEVGEKLFHARNIHQTFQLIFN 240
KTLSNVKSFYRTLITLLAHSSLTVVVFALSILSSLTLNEEVGEKLFHARNIHQTFQLIFN
Sbjct: 181 KTLSNVKSFYRTLITLLAHSSLTVVVFALSILSSLTLNEEVGEKLFHARNIHQTFQLIFN 240
Query: 241 ILINGDGTLTRKYSVDLLMDLLKNPKIADYLTRYEHFSSCLHQVLGLLNGKDPDSSSKVL 300
ILINGDGTLTRKYSVDLLMDLLKNPKIADYLTRYEHFSSCLHQVLGLLNGKDPDSSSKVL
Sbjct: 241 ILINGDGTLTRKYSVDLLMDLLKNPKIADYLTRYEHFSSCLHQVLGLLNGKDPDSSSKVL 300
Query: 301 ELLLAFCSVTQLRHMLTQMMFEQSPPGSATLGSHTKCLEPTVALLRWLSQPLDGSENCSV 360
ELLLAFCSVTQLRHMLTQMMFEQSPPGSATLGSHTKCLEPTVALLRWLSQPLDGSENCSV
Sbjct: 301 ELLLAFCSVTQLRHMLTQMMFEQSPPGSATLGSHTKCLEPTVALLRWLSQPLDGSENCSV 360
Query: 361 LALELFKEIFEDVIDAANCSSADRFVTLLLPTILDQLQFTEQNLDEALTRKKCERIAKAI 420
LALELFKEIFEDVIDAANCSSADRFVTLLLPTILDQLQFTEQNLDEALTRKKCERIAKAI
Sbjct: 361 LALELFKEIFEDVIDAANCSSADRFVTLLLPTILDQLQFTEQNLDEALTRKKCERIAKAI 420
Query: 421 EVLLTLCGDDTLKMHIAKILTTVKCTTLIEQQFTYGKIDLGFGTKVADSELCKLAADVIL 480
EVLLTLCGDDTLKMHIAKILTTVKCTTLIEQQFTYGKIDLGFGTKVADSELCKLAADVIL
Sbjct: 421 EVLLTLCGDDTLKMHIAKILTTVKCTTLIEQQFTYGKIDLGFGTKVADSELCKLAADVIL 480
Query: 481 KTLDLINKLKPLVPGMEVSFYKILQDPRLITPLAFALTSDNREQVQSGLRILLEAAPLPD 540
KTLDLINKLKPLVPGMEVSFYKILQDPRLITPLAFALTSDNREQVQSGLRILLEAAPLPD
Sbjct: 481 KTLDLINKLKPLVPGMEVSFYKILQDPRLITPLAFALTSDNREQVQSGLRILLEAAPLPD 540
Query: 541 FPALVLGESIAANNAYRQQETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGLNIEEL 600
FPALVLGESIAANNAYRQQETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGLNIEEL
Sbjct: 541 FPALVLGESIAANNAYRQQETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGLNIEEL 600
Query: 601 IEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQ 660
IEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQ
Sbjct: 601 IEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQ 660
Query: 661 HRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESV 720
HRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESV
Sbjct: 661 HRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESV 720
Query: 721 AEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQL 780
AEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQL
Sbjct: 721 AEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQL 780
Query: 781 IEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE 840
IEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE
Sbjct: 781 IEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE 840
Query: 841 QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSGGKINPET 900
QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSGGKINPET
Sbjct: 841 QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSGGKINPET 900
Query: 901 VNLSI 905
VNLSI
Sbjct: 901 VNLSI 905
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 73.6 bits (179), Expect = 8e-13
Identities = 53/220 (24%), Positives = 116/220 (52%), Gaps = 10/220 (4%)
Query: 669 ETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILT 728
E+E + ++E++RK E +LL QQ+++E E L + KL++ EE+E+
Sbjct: 234 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE-LQSVSAKLQAQVEENELWN 292
Query: 729 KSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQ---LIEKEE 785
+ Q+ E ++ + +Q + + +Q E +++ E ++EQ EK Q + EKEE
Sbjct: 293 RLNQ---QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 349
Query: 786 QRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKE 845
+ + + + ++E K+ + +EEK++ ++ +KEE I L +++ E+IR++
Sbjct: 350 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 409
Query: 846 LSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
+ E +K + + + +E+E+ + Q+E++ + I
Sbjct: 410 ---EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
Score = 65.9 bits (159), Expect = 2e-10
Identities = 50/231 (21%), Positives = 115/231 (49%), Gaps = 10/231 (4%)
Query: 653 QADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQ 712
Q ++ Q R Q E M R+ E+ +E+ + + ++ E E E + +
Sbjct: 428 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487
Query: 713 HN---RKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESL 769
R+ E + E+ E + K ++ ++ E ++ + ++ + + +Q E +++ E
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547
Query: 770 KEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETI 829
+E+ + + I +EE+R+E ++++ +E K+ +K QEEKI+ +++R+++EE
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE-- 605
Query: 830 DILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
K + E+IR E K E + + E ++ E+E + + Q+E++ +
Sbjct: 606 ----KMWKQEEKIR-EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651
Score = 63.9 bits (154), Expect = 6e-10
Identities = 48/238 (20%), Positives = 119/238 (50%), Gaps = 13/238 (5%)
Query: 661 HRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQV--ESERAQSDIEHLFQHNRKL- 717
H ++ + E + + M R+ E+ +E+ + + +++ + E+ + E +++ K+
Sbjct: 461 HEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIR 520
Query: 718 ---ESVAEEHEILTKSYMELLQRNE---STEKKNKDLQI-TCDSLNKQIETVKKLNESLK 770
E + E+ E + + ++ ++ E EK ++ +I + +Q + + + E ++
Sbjct: 521 EQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580
Query: 771 EQNEKSIAQ---LIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEE 827
EQ EK Q + E+EE+R+E + ++ +E K+ +K + QEEKI+ +++ ++EE
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Query: 828 TIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
+++ E+ E K E + E ++ E+E ++ Q+E++ + M+
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM 698
Score = 62.8 bits (151), Expect = 1e-09
Identities = 48/239 (20%), Positives = 114/239 (47%), Gaps = 15/239 (6%)
Query: 651 LAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHL 710
+ + + I + + + E + R M RE E+ +E+ + + ++ E E E
Sbjct: 519 IREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK 578
Query: 711 FQHN-----RKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKL 765
+ R+ E + E+ E + ++ ++ E ++ + +Q + + +Q E +++
Sbjct: 579 IREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Query: 766 NESLKEQNEKSIAQ---LIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKER 822
E +EQ EK Q + E+EE+ +E + + +E K+ +K + QEEKI+ ++
Sbjct: 639 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM 698
Query: 823 EDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKH 881
+++EE + +++ E+ K E + + E ++ E+E ++ Q+E++ +H
Sbjct: 699 QEQEEKMWEQEEKMCEQEE-------KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 59.7 bits (143), Expect = 1e-08
Identities = 62/296 (20%), Positives = 134/296 (45%), Gaps = 23/296 (7%)
Query: 595 LNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQA 654
LN++EL KL+ ++ Q + + L S ++LQ +E L
Sbjct: 242 LNVKELKRKLERAKLLLPQ------QQLQAEADHLGKELQSVSAKLQAQVEENELW---- 291
Query: 655 DRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHN 714
+RL Q + + E + + ++E E K E ++ Q+ + R + + +
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
Query: 715 RKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNE 774
R+ E + E E + E++ E ++ +++ + +++E E ++EQ E
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 411
Query: 775 KSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETI---DI 831
K +EE++ Q + ++E K+ +K + QEEKI+ +K+ +EE I +
Sbjct: 412 K------RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465
Query: 832 LRKELSRTEQIRKELSIKASSLEVQKA--QLEGRLEEKESLVKLQQEELNKHSHMI 885
+R+E R EQ +E+ + + Q+ + + ++ E+E ++ Q+E++ + I
Sbjct: 466 IREEEKRQEQ--EEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI 519
Score = 56.2 bits (134), Expect = 1e-07
Identities = 48/220 (21%), Positives = 103/220 (46%), Gaps = 6/220 (2%)
Query: 667 QAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLES----VAE 722
+ E +A+ ++ +R EEL+ A +E R E L + N KL+ V
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 723 EHEILTKSYMELLQRNESTE--KKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQL 780
E + + EL ++ E + + LQ D L K++++V ++ E+NE
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 781 IEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE 840
++EE+ + ++ + E K+ +K + QEEKI+ +++ +EE + +++ R E
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
Query: 841 QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
++ E K E + E ++ +E ++ ++E++ +
Sbjct: 356 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 395
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 73.2 bits (178), Expect = 1e-12
Identities = 53/220 (24%), Positives = 114/220 (51%), Gaps = 10/220 (4%)
Query: 669 ETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILT 728
E+E + ++E++RK E +LL QQ+++E E L + KL++ EE+E+
Sbjct: 234 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE-LQSVSAKLQAQVEENELWN 292
Query: 729 KSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQ---LIEKEE 785
+ Q+ E ++ + +Q + + +Q E +++ E ++EQ EK Q + EKEE
Sbjct: 293 RLNQ---QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 349
Query: 786 QRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKE 845
+ + + + ++E K+ L + +EEKI+ L+++ ++E+ I +E R E+ +
Sbjct: 350 KMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK---IREQEEKRQEEEKIR 406
Query: 846 LSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
K E + + E ++ E+E ++ Q++++ + I
Sbjct: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 446
Score = 58.5 bits (140), Expect = 3e-08
Identities = 45/232 (19%), Positives = 119/232 (51%), Gaps = 14/232 (6%)
Query: 661 HRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQV-ESERAQSDIEHLFQHNRKLES 719
H ++ + E + + M R+ E+ E+ + + +++ E E+ + E +++ K+
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH- 505
Query: 720 VAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQ 779
++ E + + ++ ++ E ++ + ++ + + +Q E +++ E + EQ EK
Sbjct: 506 --DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK---- 559
Query: 780 LIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRT 839
++++E+ + + ++ ++E K+ QK K++E++ K ++E + +E+ + +E
Sbjct: 560 -MQEQEKMRRQEEKIREQEEKIRE--QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW 616
Query: 840 EQIRK--ELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKH-SHMIAMI 888
EQ K E K E + + E ++ E+E ++ Q+E++ +H H+ A I
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 57.4 bits (137), Expect = 6e-08
Identities = 71/307 (23%), Positives = 138/307 (44%), Gaps = 31/307 (10%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL 657
EEL EK + + K Q+ + S+I ++ + L K R + LL + L A+AD L
Sbjct: 217 EELKEK-NAKLQEKLQLVESEKSEI----QLNVKELKRKLERAKLLLPQQQLQ-AEADHL 270
Query: 658 --IAQHRCQRTQAETEARTLASMLREV--------ERKNEELSVLLKAQQVESERAQSDI 707
Q + QA+ E L + L + E K +E ++ Q+ + + I
Sbjct: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 708 EHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNE 767
+ R+ E + E E + E++ E ++ +++ + +++E E
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQE 390
Query: 768 SLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEE 827
++EQ EK +EE++ Q + ++E K+ +K + QEEKI+ +K+ +EE
Sbjct: 391 KIREQEEK------RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
Query: 828 TI---DILRKELSRTEQ---IRKELSIKASS---LEVQKAQLEGRLEEKESLVKLQQEEL 878
I + +R+E R EQ R+E I+ + +K + ++ ++E V Q+E++
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
Query: 879 NKHSHMI 885
+ I
Sbjct: 505 HDQEEKI 511
Score = 57.0 bits (136), Expect = 8e-08
Identities = 50/216 (23%), Positives = 100/216 (46%), Gaps = 6/216 (2%)
Query: 667 QAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLES----VAE 722
+ E +A+ ++ +R EEL+ A +E R E L + N KL+ V
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 723 EHEILTKSYMELLQRNESTE--KKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQL 780
E + + EL ++ E + + LQ D L K++++V ++ E+NE
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 781 IEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE 840
++EE+ + ++ + E K+ +K + QEEKI+ +++ +EE + +++ R E
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
Query: 841 QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQE 876
++ E K LE + E ++ E E + Q++
Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391
Score = 56.2 bits (134), Expect = 1e-07
Identities = 48/218 (22%), Positives = 104/218 (47%), Gaps = 11/218 (5%)
Query: 667 QAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEI 726
+ E + R L M+ E E K EL K + E R Q + + R+ E E+
Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEE--KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417
Query: 727 LTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQ 786
+ + ++ ++ E ++ K + + +++Q +K+ E K Q ++ + + EK +
Sbjct: 418 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ----EKIREEEKRQEQEEMWRQEEKIRE 473
Query: 787 RKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKEL 846
++E+ Q ++ H+ +K + QEEK+ +++ D+EE I +++ R E+ +E
Sbjct: 474 QEEIWRQ-KEKMHE----QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ 528
Query: 847 SIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHM 884
K E + + E ++E+E + Q+E++ + M
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/316 (19%), Positives = 140/316 (44%), Gaps = 36/316 (11%)
Query: 595 LNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQA 654
LN++EL KL+ ++ Q + + L S ++LQ +E L
Sbjct: 242 LNVKELKRKLERAKLLLPQ------QQLQAEADHLGKELQSVSAKLQAQVEENELW---- 291
Query: 655 DRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHN 714
+RL Q + + E + + ++E E K E ++ Q+ + R + + +
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
Query: 715 RKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNE 774
R+ E + E E + E++ E ++ ++ + + +Q E ++ E ++EQ +
Sbjct: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ-EEKRQEEEKIREQEK 410
Query: 775 KSI--AQLIEKEEQRKEVQNQLVDREHKL----ANLHQKTKV--------------QEEK 814
+ A++ +EE+ +E + ++ ++E K+ +H++ K+ QEEK
Sbjct: 411 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 470
Query: 815 IKTL-----QKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKES 869
I+ QKE+ ++E I +++ R E+ + K E + + E ++ E+E
Sbjct: 471 IREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEE 530
Query: 870 LVKLQQEELNKHSHMI 885
++ Q+E++ + M+
Sbjct: 531 KIREQEEKIREQEEMM 546
Score = 35.8 bits (81), Expect = 0.19
Identities = 46/216 (21%), Positives = 88/216 (40%), Gaps = 40/216 (18%)
Query: 667 QAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEI 726
Q E EAR L S L + + EL L A + ++A +R +E + +E +
Sbjct: 155 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKA----------DRYIEELTKERDA 204
Query: 727 LTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQ 786
L+ L RN T+ E LKE+N K +L E +
Sbjct: 205 LSLE----LYRNTITD------------------------EELKEKNAKLQEKLQLVESE 236
Query: 787 RKEVQNQLVDREHKL--ANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRK 844
+ E+Q + + + KL A L + + + L KE + + +E ++ +
Sbjct: 237 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ 296
Query: 845 ELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
+ K E + + E +++E+E ++ Q+E++ +
Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
>gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1
[Homo sapiens]
Length = 871
Score = 72.0 bits (175), Expect = 2e-12
Identities = 70/304 (23%), Positives = 136/304 (44%), Gaps = 33/304 (10%)
Query: 618 RISDIMDVYEMKLSTLASKESRLQDLL---------ETKALALAQADRLIAQHRCQRTQA 668
++S + +E LS+L SK L+ L E K LA AQ + + + + +TQ
Sbjct: 267 QLSSLTQAHEEALSSLTSKAEGLEKSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQE 326
Query: 669 ETEAR-TLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
+ EA+ TL LR+ + V + ++E ++ ++HL + L + AE ++
Sbjct: 327 DLEAQVTLVENLRKYVGEQVPSEVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVR 386
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
+S +L E E+ + +Q + DSL E +K L EK A +++ + Q
Sbjct: 387 VQSLTHILALQE--EELTRKVQPS-DSLEP--EFTRKCQSLLNRWREKVFALMVQLKAQE 441
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDI-------LRKELSRTE 840
E + + + ++A+L +K Q ++ LQ+ +DK +++ L+ ELSR +
Sbjct: 442 LEHSDSVKQLKGQVASLQEKVTSQSQEQAILQRSLQDKAAEVEVERMGAKGLQLELSRAQ 501
Query: 841 QIRKELSIKASSLEVQ-----------KAQLEGRLEEKESLVKLQQEELNKHSHMIAMIH 889
+ R+ + +S E Q + LE + + E N+ S+ + +H
Sbjct: 502 EARRRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVH 561
Query: 890 SLSG 893
++ G
Sbjct: 562 TIRG 565
Score = 44.3 bits (103), Expect = 5e-04
Identities = 75/374 (20%), Positives = 153/374 (40%), Gaps = 57/374 (15%)
Query: 559 QETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICDVR 618
QE E + P S F + L ++ V L ++ ++L+ VK +
Sbjct: 397 QEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVK------Q 450
Query: 619 ISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQ------HRCQRTQAETEA 672
+ + + K+++ + +++ LQ L+ KA A + +R+ A+ R Q + +
Sbjct: 451 LKGQVASLQEKVTSQSQEQAILQRSLQDKA-AEVEVERMGAKGLQLELSRAQEARRRWQQ 509
Query: 673 RTLAS--MLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEI---- 726
+T ++ LR V + L+ + E A + + L +NR +V + H I
Sbjct: 510 QTASAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSL--NNRLSYAVRKVHTIRGLI 567
Query: 727 -------------------LTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNE 767
+T +EL Q E + + +LQ++ + +++ ++ E
Sbjct: 568 ARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQGE 627
Query: 768 SLKEQNEKSIAQLIEKEEQRKEVQNQL-----------VDREHKLANLHQKTKVQEEKIK 816
+ ++Q K QL ++ +Q +E L + + A+L Q+ Q+E
Sbjct: 628 AERQQLSKVAQQLEQELQQTQESLASLGLQLEVARQGQQESTEEAASLRQELTQQQELYG 687
Query: 817 TLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRL----EEKESLVK 872
+E+ + ET LR++LS TE+ E + + V Q++ R E + L +
Sbjct: 688 QALQEKVAEVET--RLREQLSDTERRLNEARREHAKAVVSLRQIQRRAAQEKERSQELRR 745
Query: 873 LQQEELNKHSHMIA 886
LQ+E + +A
Sbjct: 746 LQEEARKEEGQRLA 759
Score = 34.7 bits (78), Expect = 0.41
Identities = 44/218 (20%), Positives = 93/218 (42%), Gaps = 21/218 (9%)
Query: 628 MKLSTLASKESRLQDLLETKALALAQ-ADRLIAQHRCQRTQAETEARTLASMLREVERK- 685
++L L + +RL L+ A + Q R Q +R Q A+ L L++ +
Sbjct: 592 LELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQLSKVAQQLEQELQQTQESL 651
Query: 686 ---NEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTE 742
+L V + QQ +E A S + L Q +E + + L ++ TE
Sbjct: 652 ASLGLQLEVARQGQQESTEEAASLRQELTQQQELYGQALQEK--VAEVETRLREQLSDTE 709
Query: 743 KKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLV------- 795
++ + + K + +++++ ++ E+S +EE RKE +L
Sbjct: 710 RRLNEAR---REHAKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELE 766
Query: 796 -DREHKLANLHQK---TKVQEEKIKTLQKEREDKEETI 829
D+ LA L Q+ ++ +++++ T+ DK++++
Sbjct: 767 RDKNLMLATLQQEGLLSRYKQQRLLTVLPSLLDKKKSV 804
>gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2
[Homo sapiens]
Length = 835
Score = 72.0 bits (175), Expect = 2e-12
Identities = 70/304 (23%), Positives = 136/304 (44%), Gaps = 33/304 (10%)
Query: 618 RISDIMDVYEMKLSTLASKESRLQDLL---------ETKALALAQADRLIAQHRCQRTQA 668
++S + +E LS+L SK L+ L E K LA AQ + + + + +TQ
Sbjct: 231 QLSSLTQAHEEALSSLTSKAEGLEKSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQE 290
Query: 669 ETEAR-TLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
+ EA+ TL LR+ + V + ++E ++ ++HL + L + AE ++
Sbjct: 291 DLEAQVTLVENLRKYVGEQVPSEVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVR 350
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
+S +L E E+ + +Q + DSL E +K L EK A +++ + Q
Sbjct: 351 VQSLTHILALQE--EELTRKVQPS-DSLEP--EFTRKCQSLLNRWREKVFALMVQLKAQE 405
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDI-------LRKELSRTE 840
E + + + ++A+L +K Q ++ LQ+ +DK +++ L+ ELSR +
Sbjct: 406 LEHSDSVKQLKGQVASLQEKVTSQSQEQAILQRSLQDKAAEVEVERMGAKGLQLELSRAQ 465
Query: 841 QIRKELSIKASSLEVQ-----------KAQLEGRLEEKESLVKLQQEELNKHSHMIAMIH 889
+ R+ + +S E Q + LE + + E N+ S+ + +H
Sbjct: 466 EARRRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVH 525
Query: 890 SLSG 893
++ G
Sbjct: 526 TIRG 529
Score = 44.3 bits (103), Expect = 5e-04
Identities = 75/374 (20%), Positives = 153/374 (40%), Gaps = 57/374 (15%)
Query: 559 QETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICDVR 618
QE E + P S F + L ++ V L ++ ++L+ VK +
Sbjct: 361 QEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVK------Q 414
Query: 619 ISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQ------HRCQRTQAETEA 672
+ + + K+++ + +++ LQ L+ KA A + +R+ A+ R Q + +
Sbjct: 415 LKGQVASLQEKVTSQSQEQAILQRSLQDKA-AEVEVERMGAKGLQLELSRAQEARRRWQQ 473
Query: 673 RTLAS--MLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEI---- 726
+T ++ LR V + L+ + E A + + L +NR +V + H I
Sbjct: 474 QTASAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSL--NNRLSYAVRKVHTIRGLI 531
Query: 727 -------------------LTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNE 767
+T +EL Q E + + +LQ++ + +++ ++ E
Sbjct: 532 ARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQGE 591
Query: 768 SLKEQNEKSIAQLIEKEEQRKEVQNQL-----------VDREHKLANLHQKTKVQEEKIK 816
+ ++Q K QL ++ +Q +E L + + A+L Q+ Q+E
Sbjct: 592 AERQQLSKVAQQLEQELQQTQESLASLGLQLEVARQGQQESTEEAASLRQELTQQQELYG 651
Query: 817 TLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRL----EEKESLVK 872
+E+ + ET LR++LS TE+ E + + V Q++ R E + L +
Sbjct: 652 QALQEKVAEVET--RLREQLSDTERRLNEARREHAKAVVSLRQIQRRAAQEKERSQELRR 709
Query: 873 LQQEELNKHSHMIA 886
LQ+E + +A
Sbjct: 710 LQEEARKEEGQRLA 723
Score = 34.7 bits (78), Expect = 0.41
Identities = 44/218 (20%), Positives = 93/218 (42%), Gaps = 21/218 (9%)
Query: 628 MKLSTLASKESRLQDLLETKALALAQ-ADRLIAQHRCQRTQAETEARTLASMLREVERK- 685
++L L + +RL L+ A + Q R Q +R Q A+ L L++ +
Sbjct: 556 LELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQLSKVAQQLEQELQQTQESL 615
Query: 686 ---NEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTE 742
+L V + QQ +E A S + L Q +E + + L ++ TE
Sbjct: 616 ASLGLQLEVARQGQQESTEEAASLRQELTQQQELYGQALQEK--VAEVETRLREQLSDTE 673
Query: 743 KKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLV------- 795
++ + + K + +++++ ++ E+S +EE RKE +L
Sbjct: 674 RRLNEAR---REHAKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELE 730
Query: 796 -DREHKLANLHQK---TKVQEEKIKTLQKEREDKEETI 829
D+ LA L Q+ ++ +++++ T+ DK++++
Sbjct: 731 RDKNLMLATLQQEGLLSRYKQQRLLTVLPSLLDKKKSV 768
>gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3
[Homo sapiens]
Length = 782
Score = 72.0 bits (175), Expect = 2e-12
Identities = 70/304 (23%), Positives = 136/304 (44%), Gaps = 33/304 (10%)
Query: 618 RISDIMDVYEMKLSTLASKESRLQDLL---------ETKALALAQADRLIAQHRCQRTQA 668
++S + +E LS+L SK L+ L E K LA AQ + + + + +TQ
Sbjct: 178 QLSSLTQAHEEALSSLTSKAEGLEKSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQE 237
Query: 669 ETEAR-TLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
+ EA+ TL LR+ + V + ++E ++ ++HL + L + AE ++
Sbjct: 238 DLEAQVTLVENLRKYVGEQVPSEVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVR 297
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
+S +L E E+ + +Q + DSL E +K L EK A +++ + Q
Sbjct: 298 VQSLTHILALQE--EELTRKVQPS-DSLEP--EFTRKCQSLLNRWREKVFALMVQLKAQE 352
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDI-------LRKELSRTE 840
E + + + ++A+L +K Q ++ LQ+ +DK +++ L+ ELSR +
Sbjct: 353 LEHSDSVKQLKGQVASLQEKVTSQSQEQAILQRSLQDKAAEVEVERMGAKGLQLELSRAQ 412
Query: 841 QIRKELSIKASSLEVQ-----------KAQLEGRLEEKESLVKLQQEELNKHSHMIAMIH 889
+ R+ + +S E Q + LE + + E N+ S+ + +H
Sbjct: 413 EARRRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVH 472
Query: 890 SLSG 893
++ G
Sbjct: 473 TIRG 476
Score = 44.3 bits (103), Expect = 5e-04
Identities = 75/374 (20%), Positives = 153/374 (40%), Gaps = 57/374 (15%)
Query: 559 QETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICDVR 618
QE E + P S F + L ++ V L ++ ++L+ VK +
Sbjct: 308 QEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVK------Q 361
Query: 619 ISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQ------HRCQRTQAETEA 672
+ + + K+++ + +++ LQ L+ KA A + +R+ A+ R Q + +
Sbjct: 362 LKGQVASLQEKVTSQSQEQAILQRSLQDKA-AEVEVERMGAKGLQLELSRAQEARRRWQQ 420
Query: 673 RTLAS--MLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEI---- 726
+T ++ LR V + L+ + E A + + L +NR +V + H I
Sbjct: 421 QTASAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSL--NNRLSYAVRKVHTIRGLI 478
Query: 727 -------------------LTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNE 767
+T +EL Q E + + +LQ++ + +++ ++ E
Sbjct: 479 ARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQGE 538
Query: 768 SLKEQNEKSIAQLIEKEEQRKEVQNQL-----------VDREHKLANLHQKTKVQEEKIK 816
+ ++Q K QL ++ +Q +E L + + A+L Q+ Q+E
Sbjct: 539 AERQQLSKVAQQLEQELQQTQESLASLGLQLEVARQGQQESTEEAASLRQELTQQQELYG 598
Query: 817 TLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRL----EEKESLVK 872
+E+ + ET LR++LS TE+ E + + V Q++ R E + L +
Sbjct: 599 QALQEKVAEVET--RLREQLSDTERRLNEARREHAKAVVSLRQIQRRAAQEKERSQELRR 656
Query: 873 LQQEELNKHSHMIA 886
LQ+E + +A
Sbjct: 657 LQEEARKEEGQRLA 670
Score = 34.7 bits (78), Expect = 0.41
Identities = 44/218 (20%), Positives = 93/218 (42%), Gaps = 21/218 (9%)
Query: 628 MKLSTLASKESRLQDLLETKALALAQ-ADRLIAQHRCQRTQAETEARTLASMLREVERK- 685
++L L + +RL L+ A + Q R Q +R Q A+ L L++ +
Sbjct: 503 LELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQLSKVAQQLEQELQQTQESL 562
Query: 686 ---NEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTE 742
+L V + QQ +E A S + L Q +E + + L ++ TE
Sbjct: 563 ASLGLQLEVARQGQQESTEEAASLRQELTQQQELYGQALQEK--VAEVETRLREQLSDTE 620
Query: 743 KKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLV------- 795
++ + + K + +++++ ++ E+S +EE RKE +L
Sbjct: 621 RRLNEAR---REHAKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELE 677
Query: 796 -DREHKLANLHQK---TKVQEEKIKTLQKEREDKEETI 829
D+ LA L Q+ ++ +++++ T+ DK++++
Sbjct: 678 RDKNLMLATLQQEGLLSRYKQQRLLTVLPSLLDKKKSV 715
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 70.5 bits (171), Expect = 7e-12
Identities = 57/294 (19%), Positives = 144/294 (48%), Gaps = 6/294 (2%)
Query: 594 GLNIEELIEKLQSGMV--VKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALAL 651
G IE+L ++ + + ++ I D + + + KL + S++S +Q ++ L
Sbjct: 189 GTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248
Query: 652 AQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLF 711
+A L+ Q + Q +A+ + L S+ +++ + EE + Q + E+ E +
Sbjct: 249 ERAQLLLPQQQLQ-VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307
Query: 712 QHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKE 771
+ K+ E+ + + ++ ++ E ++ + ++ D + +Q E +++ E ++E
Sbjct: 308 EQEEKM---CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364
Query: 772 QNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDI 831
Q EK Q + EQ +++Q Q + + + ++ + ++EK+ +K+ +++E I
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 832 LRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
+E+ R E+ +EL E + ++E +++E+E ++ Q+E++ + I
Sbjct: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI 478
Score = 63.2 bits (152), Expect = 1e-09
Identities = 55/254 (21%), Positives = 123/254 (48%), Gaps = 7/254 (2%)
Query: 627 EMKLSTLASKESRLQDLL-ETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERK 685
E+K+ K R ++ + E + Q D++ Q R Q E M R+ E+
Sbjct: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 686 NEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKN 745
E+ K Q+ E E + + + Q ++ E + + + + + ++ ++ E ++
Sbjct: 377 REQDE---KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 746 KDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQ--LIEKEEQRKEVQNQLVDREHKLAN 803
+ ++ + + Q E ++++ E ++E+ EK Q I+++E++ + Q + R+ KL
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 804 LHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGR 863
+K QEEK+ +++ ++EE + +++ R E+ +E ++ E + + E R
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 864 LEE-KESLVKLQQE 876
L+E +E L KL Q+
Sbjct: 554 LQELEERLGKLGQK 567
Score = 60.8 bits (146), Expect = 5e-09
Identities = 64/312 (20%), Positives = 148/312 (47%), Gaps = 31/312 (9%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL 657
EEL EK + + K ++ + S+I ++ + L K R Q LL + L + +ADRL
Sbjct: 214 EELKEK-NAELQEKLRLVESEKSEI----QLNVKDLKRKLERAQLLLPQQQLQV-EADRL 267
Query: 658 --IAQHRCQRTQAETEARTLASML---------------REVERKNEELSVLLKAQQV-- 698
Q + QA+ E L ++L +E E K E + ++ Q+
Sbjct: 268 GKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKM 327
Query: 699 --ESERAQSDIEHLFQHNRKL----ESVAEEHEILTKSYMELLQRNESTEKKNKDLQITC 752
+ E+ E + + K+ E + E+ E + + ++ ++ E ++++ +Q
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 753 DSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQE 812
+ + +Q E +++ E +E+ + ++ E++E+ +E + ++ +E K+ L + + QE
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447
Query: 813 EKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVK 872
EK++ ++++ +++EE + +++ R E+ +E K E Q E E++E + +
Sbjct: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Query: 873 LQQEELNKHSHM 884
+++ + M
Sbjct: 508 QEEKMWEQEEKM 519
Score = 57.8 bits (138), Expect = 5e-08
Identities = 50/231 (21%), Positives = 115/231 (49%), Gaps = 7/231 (3%)
Query: 653 QADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQ 712
Q +++ Q R Q E R M + E+ E+ + + ++ E+ + E +
Sbjct: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368
Query: 713 HNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQ 772
R+ E + E+ E + + E+ ++ E ++ + Q + + +Q + +++ +E ++EQ
Sbjct: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQ 425
Query: 773 NEKSIAQ---LIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETI 829
E+ Q + E EE ++ + +L + E K+ +K + QEEKI+ +++ +++EE
Sbjct: 426 EEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT 485
Query: 830 DILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
K L + E+I E K E + + E +++E+E ++ Q+E++ +
Sbjct: 486 WRQEKLLKQEEKI-WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMRE 535
Score = 54.7 bits (130), Expect = 4e-07
Identities = 44/212 (20%), Positives = 103/212 (48%), Gaps = 13/212 (6%)
Query: 653 QADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQ 712
Q +++ Q + Q E R + + E++ E++ K + + E+ + E +++
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 713 HNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQ 772
K+ + E + + E+ ++ + E+K + +Q E +++ E ++EQ
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEK----------MQEQEEKIQRQEEKIQEQ 481
Query: 773 NEKSIAQ--LIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETID 830
EK+ Q L+++EE+ E + ++ +E K+ +K + QEEK++ +++ ++E +
Sbjct: 482 EEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
Query: 831 ILRKELSRTEQIRKELSIKASSLEVQKAQLEG 862
+++ E +EL + L QKA+L G
Sbjct: 542 QQEEKMQEQEVRLQELEERLGKLG-QKAELLG 572
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 70.5 bits (171), Expect = 7e-12
Identities = 58/294 (19%), Positives = 144/294 (48%), Gaps = 6/294 (2%)
Query: 594 GLNIEELIEKLQ--SGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALAL 651
G IE+L ++ S + ++ I D + + + KL + S++S +Q ++ L
Sbjct: 189 GTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248
Query: 652 AQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLF 711
+A L+ Q + Q +A+ + L S+ +++ + EE + Q + E+ E +
Sbjct: 249 ERAQLLLPQQQLQ-VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307
Query: 712 QHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKE 771
+ K+ E+ + + ++ ++ E ++ + ++ D + +Q E +++ E ++E
Sbjct: 308 EQEEKM---CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364
Query: 772 QNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDI 831
Q EK Q + EQ +++Q Q + + + ++ + ++EK+ +K+ +++E I
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 832 LRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
+E+ R E+ +EL E + ++E +++E+E ++ Q+E++ + I
Sbjct: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI 478
Score = 63.2 bits (152), Expect = 1e-09
Identities = 55/254 (21%), Positives = 123/254 (48%), Gaps = 7/254 (2%)
Query: 627 EMKLSTLASKESRLQDLL-ETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERK 685
E+K+ K R ++ + E + Q D++ Q R Q E M R+ E+
Sbjct: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 686 NEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKN 745
E+ K Q+ E E + + + Q ++ E + + + + + ++ ++ E ++
Sbjct: 377 REQDE---KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 746 KDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQ--LIEKEEQRKEVQNQLVDREHKLAN 803
+ ++ + + Q E ++++ E ++E+ EK Q I+++E++ + Q + R+ KL
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 804 LHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGR 863
+K QEEK+ +++ ++EE + +++ R E+ +E ++ E + + E R
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 864 LEE-KESLVKLQQE 876
L+E +E L KL Q+
Sbjct: 554 LQELEERLGKLGQK 567
Score = 60.8 bits (146), Expect = 5e-09
Identities = 64/312 (20%), Positives = 148/312 (47%), Gaps = 31/312 (9%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL 657
EEL EK + + K ++ + S+I ++ + L K R Q LL + L + +ADRL
Sbjct: 214 EELKEK-NAELQEKLRLVESEKSEI----QLNVKDLKRKLERAQLLLPQQQLQV-EADRL 267
Query: 658 --IAQHRCQRTQAETEARTLASML---------------REVERKNEELSVLLKAQQV-- 698
Q + QA+ E L ++L +E E K E + ++ Q+
Sbjct: 268 GKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKM 327
Query: 699 --ESERAQSDIEHLFQHNRKL----ESVAEEHEILTKSYMELLQRNESTEKKNKDLQITC 752
+ E+ E + + K+ E + E+ E + + ++ ++ E ++++ +Q
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 753 DSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQE 812
+ + +Q E +++ E +E+ + ++ E++E+ +E + ++ +E K+ L + + QE
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447
Query: 813 EKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVK 872
EK++ ++++ +++EE + +++ R E+ +E K E Q E E++E + +
Sbjct: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Query: 873 LQQEELNKHSHM 884
+++ + M
Sbjct: 508 QEEKMWEQEEKM 519
Score = 57.8 bits (138), Expect = 5e-08
Identities = 50/231 (21%), Positives = 115/231 (49%), Gaps = 7/231 (3%)
Query: 653 QADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQ 712
Q +++ Q R Q E R M + E+ E+ + + ++ E+ + E +
Sbjct: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368
Query: 713 HNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQ 772
R+ E + E+ E + + E+ ++ E ++ + Q + + +Q + +++ +E ++EQ
Sbjct: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQ 425
Query: 773 NEKSIAQ---LIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETI 829
E+ Q + E EE ++ + +L + E K+ +K + QEEKI+ +++ +++EE
Sbjct: 426 EEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT 485
Query: 830 DILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
K L + E+I E K E + + E +++E+E ++ Q+E++ +
Sbjct: 486 WRQEKLLKQEEKI-WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMRE 535
Score = 54.7 bits (130), Expect = 4e-07
Identities = 44/212 (20%), Positives = 103/212 (48%), Gaps = 13/212 (6%)
Query: 653 QADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQ 712
Q +++ Q + Q E R + + E++ E++ K + + E+ + E +++
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 713 HNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQ 772
K+ + E + + E+ ++ + E+K + +Q E +++ E ++EQ
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEK----------MQEQEEKIQRQEEKIQEQ 481
Query: 773 NEKSIAQ--LIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETID 830
EK+ Q L+++EE+ E + ++ +E K+ +K + QEEK++ +++ ++E +
Sbjct: 482 EEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
Query: 831 ILRKELSRTEQIRKELSIKASSLEVQKAQLEG 862
+++ E +EL + L QKA+L G
Sbjct: 542 QQEEKMQEQEVRLQELEERLGKLG-QKAELLG 572
Score = 45.4 bits (106), Expect = 2e-04
Identities = 39/215 (18%), Positives = 89/215 (41%), Gaps = 37/215 (17%)
Query: 708 EHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKN---------------------- 745
+H + +E + +E + L+ +E ++KN
Sbjct: 183 DHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVK 242
Query: 746 ---------------KDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEV 790
+ LQ+ D L K++++V ++ E+NE ++EE+
Sbjct: 243 DLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302
Query: 791 QNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKA 850
+ ++ ++E K+ K + QEEK+ +++ ++EE I ++ R E+ +E K
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKI 362
Query: 851 SSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
E + + E ++ E++ ++ Q+EE+ + I
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 70.5 bits (171), Expect = 7e-12
Identities = 43/221 (19%), Positives = 112/221 (50%), Gaps = 4/221 (1%)
Query: 661 HRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESV 720
H ++ + + E R +RE E++ E+ + + + ++ E+ + E + E +
Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 721 AEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQL 780
E+ E + + E+ ++ E ++ + ++ + +Q E +++ E ++EQ EK +
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK----M 469
Query: 781 IEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE 840
E+E + E + ++ ++E K+ +K + QE+KI+ +++ ++EE + +++ E
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 529
Query: 841 QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKH 881
+ E K E + + E ++ E+E ++ Q+E++ +H
Sbjct: 530 EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 70.1 bits (170), Expect = 9e-12
Identities = 58/290 (20%), Positives = 141/290 (48%), Gaps = 7/290 (2%)
Query: 597 IEELIEKLQ--SGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQA 654
IEEL ++ S + ++ I D + + + KL + S++S +Q ++ L +A
Sbjct: 183 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 242
Query: 655 DRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHN 714
L+ Q + Q +A+ + L S+ +++ + EE + + Q + E+ E + +
Sbjct: 243 KLLLPQQQLQ-AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQERE 301
Query: 715 RKLESVAE---EHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKE 771
K++ E E E + E++ E ++ +++ + +++E E ++E
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361
Query: 772 QNEK-SIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETID 830
Q EK + I ++E+R+E + ++ +E K+ +K + QEE ++ +++ ++EE +
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421
Query: 831 ILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
+E+ E+ + K E + + E ++ E+E +++ Q+E++ +
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGE 471
Score = 65.9 bits (159), Expect = 2e-10
Identities = 59/298 (19%), Positives = 135/298 (45%), Gaps = 16/298 (5%)
Query: 595 LNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASK------ESRLQDLLETKA 648
LN++EL KL+ ++ Q ++ D +L ++++K E+ L + L +
Sbjct: 230 LNVKELKRKLERAKLLLPQ---QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 286
Query: 649 LALAQADRLIAQHRCQRTQAETEA-RTLASMLREVERKNEELSVLLKAQQVESERAQSDI 707
Q R ++ Q + E R +R E E ++ Q+ + I
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
Query: 708 EHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNE 767
L + + E + E+ E + E ++ E +++ + + + +Q E +++ E
Sbjct: 347 RELEEKMHEQEKIREQEE--KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404
Query: 768 SLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEE 827
++EQ EK + E+EE+ E + ++ ++E K+ +K + QE+KI+ +++ ++EE
Sbjct: 405 MMQEQEEK----MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460
Query: 828 TIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
+ +++ E E K E + + E ++ E+E ++ Q+E++ + M+
Sbjct: 461 MMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Score = 64.7 bits (156), Expect = 4e-10
Identities = 60/249 (24%), Positives = 117/249 (46%), Gaps = 17/249 (6%)
Query: 640 LQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVE 699
L+ L A +ADR I + +R E E++ KN +L K Q VE
Sbjct: 165 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE--KLQLVE 222
Query: 700 SERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQI 759
SE+++ + ++ + RKLE K + Q + K+LQ L Q+
Sbjct: 223 SEKSEIQL-NVKELKRKLER--------AKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 273
Query: 760 ETVKKLNESLKEQNEKSIAQ---LIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIK 816
E + N ++Q EK Q + E+EE+ +E + ++ ++E K+ + +EEK++
Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR 333
Query: 817 TLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQE 876
++ +KEE I L +++ E+IR++ + E +K + + + +E+E+ + Q+E
Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQ---EEKRQEEEKIREQEKRQEQEAKMWRQEE 390
Query: 877 ELNKHSHMI 885
++ + I
Sbjct: 391 KIREQEEKI 399
Score = 60.5 bits (145), Expect = 7e-09
Identities = 45/226 (19%), Positives = 115/226 (50%), Gaps = 23/226 (10%)
Query: 667 QAETEARTLASMLREVERKNEELSVLLKAQQV-ESERAQSDIEHLFQHNRKL----ESVA 721
+ E + R L + E E+ E+ + +++ E E+ Q +++ K+ E +
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400
Query: 722 EEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLI 781
E+ E++ + ++ ++ E ++ +++Q +Q E +++ E ++EQ +K +
Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQ-------EQEEKMRRQEEKIREQEKK----IR 449
Query: 782 EKEEQRKEVQNQLVDREHKLAN-----LHQKTKVQEEKIKTLQKEREDKEETIDILRKE- 835
E+EE+ +E + + ++E K+ Q+ K+QE++ K ++E + +E+ I +E
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Query: 836 -LSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
+ E++ +E K E + + E +++E+E ++ Q+E++ +
Sbjct: 510 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Score = 38.9 bits (89), Expect = 0.022
Identities = 55/261 (21%), Positives = 103/261 (39%), Gaps = 57/261 (21%)
Query: 641 QDLLETKALALAQADRLIAQHRCQRT--------------QAETEARTLASMLREVERKN 686
Q+ L + A Q R++ CQ+T Q E EAR L S L + +
Sbjct: 106 QEALRRELEAQVQTIRILT---CQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFA 162
Query: 687 EELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 746
EL L A + ++A +R +E + +E + L+ L RN T+
Sbjct: 163 GELEQALSAVATQKKKA----------DRYIEELTKERDALSLE----LYRNTITD---- 204
Query: 747 DLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKL--ANL 804
E LKE+N K +L E ++ E+Q + + + KL A L
Sbjct: 205 --------------------EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL 244
Query: 805 HQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRL 864
+ + + L KE + + +E ++ ++ K E + + E ++
Sbjct: 245 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKI 304
Query: 865 EEKESLVKLQQEELNKHSHMI 885
+E+E ++ Q+E++ + M+
Sbjct: 305 QEQEEKIREQEEKMRRQEEMM 325
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 69.7 bits (169), Expect = 1e-11
Identities = 79/319 (24%), Positives = 146/319 (45%), Gaps = 24/319 (7%)
Query: 571 QSSNHSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKL 630
++ N S ++ L D V + L+E+L+ + KD +I + ++ E +L
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQV---SFASLVEELKKVIHEKDG----KIKSVEELLEAEL 821
Query: 631 STLASKESRLQDLL-ETKALA-------LAQADRLIAQHRCQRTQ-----AETEARTLAS 677
+A+KE +QDL E KAL L +A +L + Q Q E + T+ +
Sbjct: 822 LKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKA 881
Query: 678 MLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVA---EEHEILTKSYMEL 734
+L E E+ L+ Q E+E ++ ++ + QHN K S A EE EI+ K
Sbjct: 882 VLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENE 941
Query: 735 LQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQL 794
L+R E+ K+ + + L + ++ KL +S EQ ++ Q +E+ +
Sbjct: 942 LKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVI 1001
Query: 795 VDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLE 854
+RE +++ L + ++ ++ +K+ D E + L+ TE++ ++ + +S E
Sbjct: 1002 SEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQD-KVNKTSKE 1060
Query: 855 VQKAQLEGRLEEKESLVKL 873
Q+ LE KE L KL
Sbjct: 1061 RQQQVEAVELEAKEVLKKL 1079
Score = 65.5 bits (158), Expect = 2e-10
Identities = 52/232 (22%), Positives = 112/232 (48%), Gaps = 22/232 (9%)
Query: 658 IAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKL 717
+ Q Q+ AE A L L+E ER+ EE+ ++ + E E AQ D++ F K
Sbjct: 469 LQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV--AKE 526
Query: 718 ESVAEEHEILTKSYM-------ELLQRNESTEKK-NKDLQITCDSLNKQIETVKKLNESL 769
V H LT + + L+Q ES +K+ NK+ +SL Q++ + + NE+L
Sbjct: 527 NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKE-----ESLQMQVQDILEQNEAL 581
Query: 770 KEQNEKSIAQLIEKEEQ---RKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKE 826
K Q ++ +Q+ + +E+ + +++ ++ + +++ + ++E +D +
Sbjct: 582 KAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQ 641
Query: 827 ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 878
+L+ E+ + + + E + A LE +++ + K+ ++L +E+L
Sbjct: 642 NMNFLLKAEVQKLQALANEQAAAAHELE----KMQQSVYVKDDKIRLLEEQL 689
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/297 (22%), Positives = 137/297 (46%), Gaps = 23/297 (7%)
Query: 597 IEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADR 656
++ L KL +V K Q+ + R+ +M+ + +++ S + ++QD+LE AQ +
Sbjct: 529 VQSLHSKLTDTLVSKQQL-EQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQ 587
Query: 657 LIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQ---VESERAQSDIEH---- 709
+Q Q T A A L ++ E +++ ++ L +++ E DI++
Sbjct: 588 FHSQIAAQ-TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL 646
Query: 710 LFQHNRKLESVAEE-----HEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKK 764
L +KL+++A E HE L K + +++ + LQ + ++ + +
Sbjct: 647 LKAEVQKLQALANEQAAAAHE-LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND 705
Query: 765 LNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKERED 824
N++LK + +K Q + E+ K+V Q+ E + +K K EE ++T +
Sbjct: 706 QNKALKSEVQK--LQTLVSEQPNKDVVEQM---EKCIQEKDEKLKTVEELLETGLIQVAT 760
Query: 825 KEETIDILRKELSRTEQIRKELSIKAS---SLEVQKAQLEGRLEEKESLVKLQQEEL 878
KEE ++ +R E S + ++L K + S +L+ + EK+ +K +E L
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELL 817
Score = 47.4 bits (111), Expect = 6e-05
Identities = 62/301 (20%), Positives = 138/301 (45%), Gaps = 35/301 (11%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL 657
++++E+++ + KD+ ++ + ++ E L +A+KE L + + + L
Sbjct: 727 KDVVEQMEKCIQEKDE----KLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782
Query: 658 IAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKL 717
A+ Q + A L ++ E + K + + LL+A+ ++ + ++ L Q + L
Sbjct: 783 KAKQNDQVSFASL-VEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKAL 841
Query: 718 E-----------------SVAEEHEILTKSYMELLQRNEST-EKKNKDLQITCDSLNKQI 759
+ S +E + L K E + ++ E+K KDL T K +
Sbjct: 842 KEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANT----GKWL 897
Query: 760 ETVKKLNESLKEQNEKSIAQLIEKE----EQRKEVQNQLVDREHKLANLHQKTKVQEEKI 815
+ +++ NESLK + + +AQ KE Q +E++ L ++E++L L K +E +
Sbjct: 898 QDLQEENESLK-AHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDL 956
Query: 816 KTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQ 875
+ + +D ++ + + S+ EQ++++ +ASS + L+ E ++ + L
Sbjct: 957 SSKTQLLQDVQDENKLFK---SQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWN 1013
Query: 876 E 876
E
Sbjct: 1014 E 1014
Score = 47.0 bits (110), Expect = 8e-05
Identities = 78/355 (21%), Positives = 153/355 (43%), Gaps = 75/355 (21%)
Query: 600 LIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL-- 657
L E+L + KD+ +I D + L SKE L+D+ L A+ +L
Sbjct: 601 LAEELHKVIAEKDK----QIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQA 656
Query: 658 ------IAQHRCQRTQA-----ETEARTLASMLR-EVERKNEELSVLL---KAQQVESER 702
A H ++ Q + + R L L+ E+ K EE +L KA + E ++
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQK 716
Query: 703 AQSDIEHLFQHNR----KLESVAEEHEILTKSYMELLQ------------------RNES 740
Q+ + Q N+ ++E +E + K+ ELL+ N S
Sbjct: 717 LQTLVSE--QPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSS 774
Query: 741 TEKKNKDL------QITCDSLNKQ-----------IETVKKLNES--LKEQNEKSIAQLI 781
K+ +DL Q++ SL ++ I++V++L E+ LK N++ Q +
Sbjct: 775 LTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDL 834
Query: 782 EKEEQ--RKEVQNQLVDREHKLA------NLHQKTKVQEEKIKTLQKEREDKEETIDILR 833
++E + ++E+ N +++ +L+ L K +EE++ T++ E+KE+ +
Sbjct: 835 KQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTG 894
Query: 834 KELSRTEQIRKELSIKASSL---EVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
K L ++ + L + +++A + EE E ++K ++ EL + M+
Sbjct: 895 KWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAML 949
Score = 45.1 bits (105), Expect = 3e-04
Identities = 46/200 (23%), Positives = 94/200 (47%), Gaps = 16/200 (8%)
Query: 666 TQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHE 725
T E + L L+E + E+ LL Q+E E+ +S + +KL+ E+ E
Sbjct: 1109 TSGSEEVKVLEHKLKEAD----EMHTLL---QLECEKYKSVLAETEGILQKLQRSVEQEE 1161
Query: 726 ILTK-----SYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQL 780
K S+ + Q S ++L+ S NK IE +++ E L+ + EK+ +
Sbjct: 1162 NKWKVKVDESHKTIKQMQSSFTSSEQELE-RLRSENKDIENLRREREHLEMELEKAEMER 1220
Query: 781 IEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE 840
+ +E+++ L + + KL + + + Q E++ L+ + ET+ LR E + +
Sbjct: 1221 STYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQ---LNETLTKLRTEQNERQ 1277
Query: 841 QIRKELSIKASSLEVQKAQL 860
++ +L SLE+ ++++
Sbjct: 1278 KVAGDLHKAQQSLELIQSKI 1297
Score = 40.0 bits (92), Expect = 0.010
Identities = 51/218 (23%), Positives = 95/218 (43%), Gaps = 43/218 (19%)
Query: 668 AETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
+E EA + +L+E + V+ A + S+ + + H Q KL + +E
Sbjct: 297 SEDEALCVVDLLKE------KSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAA 350
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
TK + L + TEK+ ++ IT + +I T++K E ++ Q
Sbjct: 351 TKDRCKQLTQEMMTEKERSNVVIT--RMKDRIGTLEK---------EHNVFQ-------- 391
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDK----EETIDILRKELSR-TEQI 842
+K+ +Q+T+ + K + ++++ E + ++ ILR +S T Q+
Sbjct: 392 -----------NKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQL 440
Query: 843 RKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
+ S + + L A+L L EK KLQQEE+ K
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTG--KLQQEEVQK 476
Score = 37.7 bits (86), Expect = 0.049
Identities = 47/230 (20%), Positives = 101/230 (43%), Gaps = 37/230 (16%)
Query: 694 KAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL-------------TKSYMELLQRNES 740
KA++ + + S+ + +H KL+ E H +L T+ ++ LQR S
Sbjct: 1101 KAKECMAGTSGSEEVKVLEH--KLKEADEMHTLLQLECEKYKSVLAETEGILQKLQR--S 1156
Query: 741 TEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREH- 799
E++ ++ D +K T+K++ S + +L + K+++N +REH
Sbjct: 1157 VEQEENKWKVKVDESHK---TIKQMQSSFTSSEQ----ELERLRSENKDIENLRREREHL 1209
Query: 800 ----KLANLHQKTKVQE-----EKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKA 850
+ A + + T V E + + LQK+ +D +EL+ + E K
Sbjct: 1210 EMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKL 1269
Query: 851 SSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSGGKINPET 900
+ + ++ ++ G L + + ++L Q ++ K + +I + ++PET
Sbjct: 1270 RTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIEN---SDVSPET 1316
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 69.7 bits (169), Expect = 1e-11
Identities = 79/319 (24%), Positives = 146/319 (45%), Gaps = 24/319 (7%)
Query: 571 QSSNHSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKL 630
++ N S ++ L D V + L+E+L+ + KD +I + ++ E +L
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQV---SFASLVEELKKVIHEKDG----KIKSVEELLEAEL 821
Query: 631 STLASKESRLQDLL-ETKALA-------LAQADRLIAQHRCQRTQ-----AETEARTLAS 677
+A+KE +QDL E KAL L +A +L + Q Q E + T+ +
Sbjct: 822 LKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKA 881
Query: 678 MLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVA---EEHEILTKSYMEL 734
+L E E+ L+ Q E+E ++ ++ + QHN K S A EE EI+ K
Sbjct: 882 VLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENE 941
Query: 735 LQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQL 794
L+R E+ K+ + + L + ++ KL +S EQ ++ Q +E+ +
Sbjct: 942 LKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVI 1001
Query: 795 VDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLE 854
+RE +++ L + ++ ++ +K+ D E + L+ TE++ ++ + +S E
Sbjct: 1002 SEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQD-KVNKTSKE 1060
Query: 855 VQKAQLEGRLEEKESLVKL 873
Q+ LE KE L KL
Sbjct: 1061 RQQQVEAVELEAKEVLKKL 1079
Score = 65.5 bits (158), Expect = 2e-10
Identities = 52/232 (22%), Positives = 112/232 (48%), Gaps = 22/232 (9%)
Query: 658 IAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKL 717
+ Q Q+ AE A L L+E ER+ EE+ ++ + E E AQ D++ F K
Sbjct: 469 LQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV--AKE 526
Query: 718 ESVAEEHEILTKSYM-------ELLQRNESTEKK-NKDLQITCDSLNKQIETVKKLNESL 769
V H LT + + L+Q ES +K+ NK+ +SL Q++ + + NE+L
Sbjct: 527 NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKE-----ESLQMQVQDILEQNEAL 581
Query: 770 KEQNEKSIAQLIEKEEQ---RKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKE 826
K Q ++ +Q+ + +E+ + +++ ++ + +++ + ++E +D +
Sbjct: 582 KAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQ 641
Query: 827 ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 878
+L+ E+ + + + E + A LE +++ + K+ ++L +E+L
Sbjct: 642 NMNFLLKAEVQKLQALANEQAAAAHELE----KMQQSVYVKDDKIRLLEEQL 689
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/297 (22%), Positives = 137/297 (46%), Gaps = 23/297 (7%)
Query: 597 IEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADR 656
++ L KL +V K Q+ + R+ +M+ + +++ S + ++QD+LE AQ +
Sbjct: 529 VQSLHSKLTDTLVSKQQL-EQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQ 587
Query: 657 LIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQ---VESERAQSDIEH---- 709
+Q Q T A A L ++ E +++ ++ L +++ E DI++
Sbjct: 588 FHSQIAAQ-TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL 646
Query: 710 LFQHNRKLESVAEE-----HEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKK 764
L +KL+++A E HE L K + +++ + LQ + ++ + +
Sbjct: 647 LKAEVQKLQALANEQAAAAHE-LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND 705
Query: 765 LNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKERED 824
N++LK + +K Q + E+ K+V Q+ E + +K K EE ++T +
Sbjct: 706 QNKALKSEVQK--LQTLVSEQPNKDVVEQM---EKCIQEKDEKLKTVEELLETGLIQVAT 760
Query: 825 KEETIDILRKELSRTEQIRKELSIKAS---SLEVQKAQLEGRLEEKESLVKLQQEEL 878
KEE ++ +R E S + ++L K + S +L+ + EK+ +K +E L
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELL 817
Score = 47.4 bits (111), Expect = 6e-05
Identities = 62/301 (20%), Positives = 138/301 (45%), Gaps = 35/301 (11%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL 657
++++E+++ + KD+ ++ + ++ E L +A+KE L + + + L
Sbjct: 727 KDVVEQMEKCIQEKDE----KLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782
Query: 658 IAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKL 717
A+ Q + A L ++ E + K + + LL+A+ ++ + ++ L Q + L
Sbjct: 783 KAKQNDQVSFASL-VEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKAL 841
Query: 718 E-----------------SVAEEHEILTKSYMELLQRNEST-EKKNKDLQITCDSLNKQI 759
+ S +E + L K E + ++ E+K KDL T K +
Sbjct: 842 KEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANT----GKWL 897
Query: 760 ETVKKLNESLKEQNEKSIAQLIEKE----EQRKEVQNQLVDREHKLANLHQKTKVQEEKI 815
+ +++ NESLK + + +AQ KE Q +E++ L ++E++L L K +E +
Sbjct: 898 QDLQEENESLK-AHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDL 956
Query: 816 KTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQ 875
+ + +D ++ + + S+ EQ++++ +ASS + L+ E ++ + L
Sbjct: 957 SSKTQLLQDVQDENKLFK---SQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWN 1013
Query: 876 E 876
E
Sbjct: 1014 E 1014
Score = 47.0 bits (110), Expect = 8e-05
Identities = 78/355 (21%), Positives = 153/355 (43%), Gaps = 75/355 (21%)
Query: 600 LIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL-- 657
L E+L + KD+ +I D + L SKE L+D+ L A+ +L
Sbjct: 601 LAEELHKVIAEKDK----QIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQA 656
Query: 658 ------IAQHRCQRTQA-----ETEARTLASMLR-EVERKNEELSVLL---KAQQVESER 702
A H ++ Q + + R L L+ E+ K EE +L KA + E ++
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQK 716
Query: 703 AQSDIEHLFQHNR----KLESVAEEHEILTKSYMELLQ------------------RNES 740
Q+ + Q N+ ++E +E + K+ ELL+ N S
Sbjct: 717 LQTLVSE--QPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSS 774
Query: 741 TEKKNKDL------QITCDSLNKQ-----------IETVKKLNES--LKEQNEKSIAQLI 781
K+ +DL Q++ SL ++ I++V++L E+ LK N++ Q +
Sbjct: 775 LTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDL 834
Query: 782 EKEEQ--RKEVQNQLVDREHKLA------NLHQKTKVQEEKIKTLQKEREDKEETIDILR 833
++E + ++E+ N +++ +L+ L K +EE++ T++ E+KE+ +
Sbjct: 835 KQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTG 894
Query: 834 KELSRTEQIRKELSIKASSL---EVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
K L ++ + L + +++A + EE E ++K ++ EL + M+
Sbjct: 895 KWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAML 949
Score = 45.1 bits (105), Expect = 3e-04
Identities = 46/200 (23%), Positives = 94/200 (47%), Gaps = 16/200 (8%)
Query: 666 TQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHE 725
T E + L L+E + E+ LL Q+E E+ +S + +KL+ E+ E
Sbjct: 1109 TSGSEEVKVLEHKLKEAD----EMHTLL---QLECEKYKSVLAETEGILQKLQRSVEQEE 1161
Query: 726 ILTK-----SYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQL 780
K S+ + Q S ++L+ S NK IE +++ E L+ + EK+ +
Sbjct: 1162 NKWKVKVDESHKTIKQMQSSFTSSEQELE-RLRSENKDIENLRREREHLEMELEKAEMER 1220
Query: 781 IEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE 840
+ +E+++ L + + KL + + + Q E++ L+ + ET+ LR E + +
Sbjct: 1221 STYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQ---LNETLTKLRTEQNERQ 1277
Query: 841 QIRKELSIKASSLEVQKAQL 860
++ +L SLE+ ++++
Sbjct: 1278 KVAGDLHKAQQSLELIQSKI 1297
Score = 40.0 bits (92), Expect = 0.010
Identities = 51/218 (23%), Positives = 95/218 (43%), Gaps = 43/218 (19%)
Query: 668 AETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
+E EA + +L+E + V+ A + S+ + + H Q KL + +E
Sbjct: 297 SEDEALCVVDLLKE------KSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAA 350
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
TK + L + TEK+ ++ IT + +I T++K E ++ Q
Sbjct: 351 TKDRCKQLTQEMMTEKERSNVVIT--RMKDRIGTLEK---------EHNVFQ-------- 391
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDK----EETIDILRKELSR-TEQI 842
+K+ +Q+T+ + K + ++++ E + ++ ILR +S T Q+
Sbjct: 392 -----------NKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQL 440
Query: 843 RKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
+ S + + L A+L L EK KLQQEE+ K
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTG--KLQQEEVQK 476
Score = 37.7 bits (86), Expect = 0.049
Identities = 47/230 (20%), Positives = 101/230 (43%), Gaps = 37/230 (16%)
Query: 694 KAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL-------------TKSYMELLQRNES 740
KA++ + + S+ + +H KL+ E H +L T+ ++ LQR S
Sbjct: 1101 KAKECMAGTSGSEEVKVLEH--KLKEADEMHTLLQLECEKYKSVLAETEGILQKLQR--S 1156
Query: 741 TEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREH- 799
E++ ++ D +K T+K++ S + +L + K+++N +REH
Sbjct: 1157 VEQEENKWKVKVDESHK---TIKQMQSSFTSSEQ----ELERLRSENKDIENLRREREHL 1209
Query: 800 ----KLANLHQKTKVQE-----EKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKA 850
+ A + + T V E + + LQK+ +D +EL+ + E K
Sbjct: 1210 EMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKL 1269
Query: 851 SSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSGGKINPET 900
+ + ++ ++ G L + + ++L Q ++ K + +I + ++PET
Sbjct: 1270 RTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIEN---SDVSPET 1316
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 68.6 bits (166), Expect = 3e-11
Identities = 67/295 (22%), Positives = 137/295 (46%), Gaps = 30/295 (10%)
Query: 605 QSGMVVKDQICDVRI--SDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHR 662
+S ++KD C V+ + + +V ++K T A+ ++++ L + LI +
Sbjct: 591 ESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTL-----------EILIEDDK 639
Query: 663 CQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLE---- 718
+ Q E ++ E+ K + L ++V L Q+ KLE
Sbjct: 640 QKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIE 699
Query: 719 SVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIA 778
S++ E+E L K+ E + L+I C ++ Q ET++KL + L+E++E I
Sbjct: 700 SLSRENECLRKT----------NESDSDALRIKCKIIDDQTETIRKLKDCLQEKDE-HIK 748
Query: 779 QLIEK-EEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELS 837
+L EK E K Q QL ++ +L + +K + E+ + L+++ + KE ++ +RK S
Sbjct: 749 RLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYS 808
Query: 838 RTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEE-LNKHSHMIAMIHSL 891
+ + LE Q +++ + E KE +K ++++ + + + +HS+
Sbjct: 809 TLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLHSM 863
Score = 43.9 bits (102), Expect = 7e-04
Identities = 76/329 (23%), Positives = 130/329 (39%), Gaps = 57/329 (17%)
Query: 597 IEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADR 656
+E ++ KLQ+ + + V + D E L L + E L+ + K A R
Sbjct: 396 LEVMVHKLQNEI----KKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIR 451
Query: 657 LIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLF----- 711
LI + + + A+ E L + L + ++L LL ++ E R + + F
Sbjct: 452 LIQEVELKASAADREIYLLRTSLHREREQAQQLHQLLALKEQE-HRKELETREFFTDADF 510
Query: 712 -------------QHNRKLESVAEEHEILTKSYMELLQR--------------------N 738
+H + ++ E+ ++L++ YM+L N
Sbjct: 511 QDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIALTVEARRFQDVKDGFEN 570
Query: 739 ESTE-KKNKDLQITCDSL-NKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVD 796
+TE K+K I N+ +K L +KEQ K K+E +QNQ+
Sbjct: 571 VATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINT 630
Query: 797 REHKLANLHQKTKVQEEKIK----TLQKEREDKEETIDILRKELSRTEQIRKELSIKASS 852
E + + QK+ +Q E +K L E KE I LR E + EL+ + SS
Sbjct: 631 LEILIEDDKQKS-IQIELLKHEKVQLISELAAKESLIFGLRTE---RKVWGHELAQQGSS 686
Query: 853 LEVQKAQLEGRLE----EKESLVKLQQEE 877
L + +LE ++E E E L K + +
Sbjct: 687 LAQNRGKLEAQIESLSRENECLRKTNESD 715
Score = 30.8 bits (68), Expect = 6.0
Identities = 37/195 (18%), Positives = 86/195 (44%), Gaps = 8/195 (4%)
Query: 700 SERAQSDIEHLFQHNRKLESVAEEH-EILTKSYMELLQRNESTEKKNKDLQITCDSLNKQ 758
SE +++ E+ Q+ KL+ + ++ ++L ++ + E + +D IT +S
Sbjct: 187 SEPEKNNHENDLQNEIKLQKLDDQILQLLNETSNSIDNVLEKDPRPKRDTDITSES---D 243
Query: 759 IETVKKLNESLKEQNEKSI-AQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKT 817
K+ N + +++ A+ I+ + + N V K+ + K +
Sbjct: 244 YGNRKECNRKVPRRSKIPYDAKTIQTIKHHNKNYNSFVSCNRKMKPPYLKELYVSSSLAN 303
Query: 818 LQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEE 877
+E ++ +I++ + S +E + ++ E +K R E+ E+ + +E
Sbjct: 304 CPMLQESEKPKTEIIKVDQSHSEDNTYQSLVEQLDQEREK---RWRAEQAENKLMDYIDE 360
Query: 878 LNKHSHMIAMIHSLS 892
L+KH++ IHSL+
Sbjct: 361 LHKHANEKEDIHSLA 375
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 68.6 bits (166), Expect = 3e-11
Identities = 67/295 (22%), Positives = 137/295 (46%), Gaps = 30/295 (10%)
Query: 605 QSGMVVKDQICDVRI--SDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHR 662
+S ++KD C V+ + + +V ++K T A+ ++++ L + LI +
Sbjct: 684 ESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTL-----------EILIEDDK 732
Query: 663 CQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLE---- 718
+ Q E ++ E+ K + L ++V L Q+ KLE
Sbjct: 733 QKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIE 792
Query: 719 SVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIA 778
S++ E+E L K+ E + L+I C ++ Q ET++KL + L+E++E I
Sbjct: 793 SLSRENECLRKT----------NESDSDALRIKCKIIDDQTETIRKLKDCLQEKDE-HIK 841
Query: 779 QLIEK-EEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELS 837
+L EK E K Q QL ++ +L + +K + E+ + L+++ + KE ++ +RK S
Sbjct: 842 RLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYS 901
Query: 838 RTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEE-LNKHSHMIAMIHSL 891
+ + LE Q +++ + E KE +K ++++ + + + +HS+
Sbjct: 902 TLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLHSM 956
Score = 43.9 bits (102), Expect = 7e-04
Identities = 76/329 (23%), Positives = 130/329 (39%), Gaps = 57/329 (17%)
Query: 597 IEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADR 656
+E ++ KLQ+ + + V + D E L L + E L+ + K A R
Sbjct: 489 LEVMVHKLQNEI----KKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIR 544
Query: 657 LIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLF----- 711
LI + + + A+ E L + L + ++L LL ++ E R + + F
Sbjct: 545 LIQEVELKASAADREIYLLRTSLHREREQAQQLHQLLALKEQE-HRKELETREFFTDADF 603
Query: 712 -------------QHNRKLESVAEEHEILTKSYMELLQR--------------------N 738
+H + ++ E+ ++L++ YM+L N
Sbjct: 604 QDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIALTVEARRFQDVKDGFEN 663
Query: 739 ESTE-KKNKDLQITCDSL-NKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVD 796
+TE K+K I N+ +K L +KEQ K K+E +QNQ+
Sbjct: 664 VATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINT 723
Query: 797 REHKLANLHQKTKVQEEKIK----TLQKEREDKEETIDILRKELSRTEQIRKELSIKASS 852
E + + QK+ +Q E +K L E KE I LR E + EL+ + SS
Sbjct: 724 LEILIEDDKQKS-IQIELLKHEKVQLISELAAKESLIFGLRTE---RKVWGHELAQQGSS 779
Query: 853 LEVQKAQLEGRLE----EKESLVKLQQEE 877
L + +LE ++E E E L K + +
Sbjct: 780 LAQNRGKLEAQIESLSRENECLRKTNESD 808
Score = 30.8 bits (68), Expect = 6.0
Identities = 37/195 (18%), Positives = 86/195 (44%), Gaps = 8/195 (4%)
Query: 700 SERAQSDIEHLFQHNRKLESVAEEH-EILTKSYMELLQRNESTEKKNKDLQITCDSLNKQ 758
SE +++ E+ Q+ KL+ + ++ ++L ++ + E + +D IT +S
Sbjct: 280 SEPEKNNHENDLQNEIKLQKLDDQILQLLNETSNSIDNVLEKDPRPKRDTDITSES---D 336
Query: 759 IETVKKLNESLKEQNEKSI-AQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKT 817
K+ N + +++ A+ I+ + + N V K+ + K +
Sbjct: 337 YGNRKECNRKVPRRSKIPYDAKTIQTIKHHNKNYNSFVSCNRKMKPPYLKELYVSSSLAN 396
Query: 818 LQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEE 877
+E ++ +I++ + S +E + ++ E +K R E+ E+ + +E
Sbjct: 397 CPMLQESEKPKTEIIKVDQSHSEDNTYQSLVEQLDQEREK---RWRAEQAENKLMDYIDE 453
Query: 878 LNKHSHMIAMIHSLS 892
L+KH++ IHSL+
Sbjct: 454 LHKHANEKEDIHSLA 468
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 67.4 bits (163), Expect = 6e-11
Identities = 84/355 (23%), Positives = 156/355 (43%), Gaps = 47/355 (13%)
Query: 571 QSSNHSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKL 630
++ N S ++ L D V + L+E+L+ + KD +I + ++ E +L
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQV---SFASLVEELKKVIHEKDG----KIKSVEELLEAEL 821
Query: 631 STLASKESRLQDLL-ETKALA-------LAQADRLIAQHRCQRTQ-----AETEARTLAS 677
+A+KE +QDL E KAL L +A +L + Q Q E + T+ +
Sbjct: 822 LKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKA 881
Query: 678 MLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVA---EEHEILTKSYMEL 734
+L E E+ L+ Q E+E ++ ++ + QHN K S A EE EI+ K
Sbjct: 882 VLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENE 941
Query: 735 LQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQL 794
L+R E+ K+ + + L + ++ KL +S EQ ++ Q +E+ +
Sbjct: 942 LKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVI 1001
Query: 795 VDREHKLANLHQKTKVQEEKIKTLQK---EREDKEETIDILRKELSRT------------ 839
+RE +++ L + ++ ++ +K ER+ + E +++ KE+ +
Sbjct: 1002 SEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLS 1061
Query: 840 --------EQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIA 886
E+ KE S E K LE +L+E + + L Q E K+ ++A
Sbjct: 1062 YGEWLHGFEKKAKECMAGTSGSEEVKV-LEHKLKEADEMHTLLQLECEKYKSVLA 1115
Score = 65.5 bits (158), Expect = 2e-10
Identities = 52/232 (22%), Positives = 112/232 (48%), Gaps = 22/232 (9%)
Query: 658 IAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKL 717
+ Q Q+ AE A L L+E ER+ EE+ ++ + E E AQ D++ F K
Sbjct: 469 LQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV--AKE 526
Query: 718 ESVAEEHEILTKSYM-------ELLQRNESTEKK-NKDLQITCDSLNKQIETVKKLNESL 769
V H LT + + L+Q ES +K+ NK+ +SL Q++ + + NE+L
Sbjct: 527 NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKE-----ESLQMQVQDILEQNEAL 581
Query: 770 KEQNEKSIAQLIEKEEQ---RKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKE 826
K Q ++ +Q+ + +E+ + +++ ++ + +++ + ++E +D +
Sbjct: 582 KAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQ 641
Query: 827 ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 878
+L+ E+ + + + E + A LE +++ + K+ ++L +E+L
Sbjct: 642 NMNFLLKAEVQKLQALANEQAAAAHELE----KMQQSVYVKDDKIRLLEEQL 689
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/297 (22%), Positives = 137/297 (46%), Gaps = 23/297 (7%)
Query: 597 IEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADR 656
++ L KL +V K Q+ + R+ +M+ + +++ S + ++QD+LE AQ +
Sbjct: 529 VQSLHSKLTDTLVSKQQL-EQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQ 587
Query: 657 LIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQ---VESERAQSDIEH---- 709
+Q Q T A A L ++ E +++ ++ L +++ E DI++
Sbjct: 588 FHSQIAAQ-TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL 646
Query: 710 LFQHNRKLESVAEE-----HEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKK 764
L +KL+++A E HE L K + +++ + LQ + ++ + +
Sbjct: 647 LKAEVQKLQALANEQAAAAHE-LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND 705
Query: 765 LNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKERED 824
N++LK + +K Q + E+ K+V Q+ E + +K K EE ++T +
Sbjct: 706 QNKALKSEVQK--LQTLVSEQPNKDVVEQM---EKCIQEKDEKLKTVEELLETGLIQVAT 760
Query: 825 KEETIDILRKELSRTEQIRKELSIKAS---SLEVQKAQLEGRLEEKESLVKLQQEEL 878
KEE ++ +R E S + ++L K + S +L+ + EK+ +K +E L
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELL 817
Score = 47.0 bits (110), Expect = 8e-05
Identities = 78/355 (21%), Positives = 153/355 (43%), Gaps = 75/355 (21%)
Query: 600 LIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL-- 657
L E+L + KD+ +I D + L SKE L+D+ L A+ +L
Sbjct: 601 LAEELHKVIAEKDK----QIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQA 656
Query: 658 ------IAQHRCQRTQA-----ETEARTLASMLR-EVERKNEELSVLL---KAQQVESER 702
A H ++ Q + + R L L+ E+ K EE +L KA + E ++
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQK 716
Query: 703 AQSDIEHLFQHNR----KLESVAEEHEILTKSYMELLQ------------------RNES 740
Q+ + Q N+ ++E +E + K+ ELL+ N S
Sbjct: 717 LQTLVSE--QPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSS 774
Query: 741 TEKKNKDL------QITCDSLNKQ-----------IETVKKLNES--LKEQNEKSIAQLI 781
K+ +DL Q++ SL ++ I++V++L E+ LK N++ Q +
Sbjct: 775 LTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDL 834
Query: 782 EKEEQ--RKEVQNQLVDREHKLA------NLHQKTKVQEEKIKTLQKEREDKEETIDILR 833
++E + ++E+ N +++ +L+ L K +EE++ T++ E+KE+ +
Sbjct: 835 KQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTG 894
Query: 834 KELSRTEQIRKELSIKASSL---EVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
K L ++ + L + +++A + EE E ++K ++ EL + M+
Sbjct: 895 KWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAML 949
Score = 40.0 bits (92), Expect = 0.010
Identities = 51/218 (23%), Positives = 95/218 (43%), Gaps = 43/218 (19%)
Query: 668 AETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
+E EA + +L+E + V+ A + S+ + + H Q KL + +E
Sbjct: 297 SEDEALCVVDLLKE------KSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAA 350
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
TK + L + TEK+ ++ IT + +I T++K E ++ Q
Sbjct: 351 TKDRCKQLTQEMMTEKERSNVVIT--RMKDRIGTLEK---------EHNVFQ-------- 391
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDK----EETIDILRKELSR-TEQI 842
+K+ +Q+T+ + K + ++++ E + ++ ILR +S T Q+
Sbjct: 392 -----------NKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQL 440
Query: 843 RKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
+ S + + L A+L L EK KLQQEE+ K
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTG--KLQQEEVQK 476
Score = 38.5 bits (88), Expect = 0.029
Identities = 36/180 (20%), Positives = 81/180 (45%), Gaps = 24/180 (13%)
Query: 694 KAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL-------------TKSYMELLQRNES 740
KA++ + + S+ + +H KL+ E H +L T+ ++ LQR S
Sbjct: 1072 KAKECMAGTSGSEEVKVLEH--KLKEADEMHTLLQLECEKYKSVLAETEGILQKLQR--S 1127
Query: 741 TEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHK 800
E++ ++ D +K T+K++ S + +L + K+++N +REH
Sbjct: 1128 VEQEENKWKVKVDESHK---TIKQMQSSFTSSEQ----ELERLRSENKDIENLRREREHL 1180
Query: 801 LANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQL 860
L + + + +++ + ET+ LR E + +++ +L SLE+ ++++
Sbjct: 1181 EMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1240
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 67.4 bits (163), Expect = 6e-11
Identities = 48/240 (20%), Positives = 116/240 (48%), Gaps = 14/240 (5%)
Query: 658 IAQHRCQRTQAETEARTLASMLREVE---RKNEELSVLLKAQQVESERAQSDIEHLFQHN 714
+ + Q + E + R +RE E R+ E + Q E E + E Q
Sbjct: 159 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQ-- 216
Query: 715 RKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNE 774
++ E + E+ E + K ++ ++ E +K+ + +Q + + KQ E +++ E ++EQ E
Sbjct: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEE 276
Query: 775 KSIAQLI---------EKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDK 825
+ + Q E+EEQ +E + Q+ ++E ++ ++ + QEE++ +++ ++
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336
Query: 826 EETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
+E + ++++ + E+ E + E Q + E ++ ++E ++ Q+E++ K +
Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQM 396
Score = 63.9 bits (154), Expect = 6e-10
Identities = 47/230 (20%), Positives = 112/230 (48%), Gaps = 18/230 (7%)
Query: 664 QRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEE 723
Q Q + + + ++ ++ E++ + Q + E+ Q E Q ++ E + E+
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEE---QMRKQEEQMREQ 267
Query: 724 HEILTKSYMELLQRNESTEKKNK------DLQITCDSLNKQIETVKKLNESLKEQNE--- 774
E + + ++L++ E TE++ + ++ + + +Q E +++ E ++EQ E
Sbjct: 268 EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMG 327
Query: 775 KSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRK 834
K Q+ E++EQ E + Q+ +E ++ ++ + QEE+++ +++ +EE +RK
Sbjct: 328 KQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQ---MRK 384
Query: 835 ELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHM 884
+ EQ+RK+ E Q E E++E + + +++ + HM
Sbjct: 385 Q---EEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
Score = 57.0 bits (136), Expect = 8e-08
Identities = 40/213 (18%), Positives = 102/213 (47%), Gaps = 8/213 (3%)
Query: 660 QHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLES 719
Q R Q Q + + +V+++ E++ + + + E+ + E + + + E
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287
Query: 720 ---VAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKS 776
E+ E + + ++ ++ E ++ + ++ + + KQ E + + E + EQ E
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE-- 345
Query: 777 IAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKEL 836
Q+ ++EEQ E + Q+ +E ++ ++ + QEE+++ +++ +EE + ++++
Sbjct: 346 --QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQM 403
Query: 837 -SRTEQIRKELSIKASSLEVQKAQLEGRLEEKE 868
+ EQ+R++ E + Q E E+KE
Sbjct: 404 GEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 50.8 bits (120), Expect = 6e-06
Identities = 57/296 (19%), Positives = 130/296 (43%), Gaps = 23/296 (7%)
Query: 592 VPGLNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALAL 651
+P + EEL EK + + + + + E + S + L+ LET + L
Sbjct: 1 MPRITNEELKEK------------NAELQEELQLVETEKSEIQLHIKELKRKLETDKIPL 48
Query: 652 AQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLF 711
Q ++ Q R Q E + R +RE E + E ++ Q+ + + +
Sbjct: 49 PQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 107
Query: 712 QHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK-DLQITCDSLNKQIETVKKLNESLK 770
R+ E E E + ++ E ++ + ++ + +Q V++ ++
Sbjct: 108 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167
Query: 771 EQN---EKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEE 827
EQ + Q+ E+E Q +E + Q+ ++E ++ ++ QEE+ +QK+ E E
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQ---MQKQEEQMGE 224
Query: 828 TIDILRKELSRTEQIRKELSIKASSLEVQKAQL---EGRLEEKESLVKLQQEELNK 880
+ +RK+ + + +++ + ++ Q+ Q+ E ++ E+E ++ Q+E++ K
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 67.0 bits (162), Expect = 8e-11
Identities = 67/326 (20%), Positives = 144/326 (44%), Gaps = 15/326 (4%)
Query: 579 TSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKES 638
T I L +++D +E+ I+ L++ V+ + + I I +VY+ + +K
Sbjct: 385 TKIASLERNIRD------LEDEIQMLKANGVLNTEDREEEIKQI-EVYKSHSKFMKTKID 437
Query: 639 RLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQV 698
+L+ L K L + Q + + L L E++ L + A ++
Sbjct: 438 QLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRL 497
Query: 699 ESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQ 758
E +S L + ++L+ + EE L ++ E E+K LQ ++L +Q
Sbjct: 498 RLEEKES---FLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQ 554
Query: 759 IETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQE----EK 814
+ K +LK++ + + ++ L ++E + L ++ + + E+
Sbjct: 555 LRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEE 614
Query: 815 IKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQ 874
I++ +KE +D +E ++ L+ EL+ E +L ASSL + + +L+ E ++ +
Sbjct: 615 IESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQK 674
Query: 875 QEELNKHSHMIAMIHSL-SGGKINPE 899
+EE +K + H++ ++NPE
Sbjct: 675 KEECSKLEAQLKKAHNIEDDSRMNPE 700
Score = 60.5 bits (145), Expect = 7e-09
Identities = 72/304 (23%), Positives = 130/304 (42%), Gaps = 35/304 (11%)
Query: 601 IEKLQSGMVVKDQ---ICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQA--- 654
IE L+ + K+Q I + + E K S L K +LQDL E K +
Sbjct: 471 IEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDM 530
Query: 655 -DRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDI----EH 709
D L + R + + + L LR+ +++ L +K+ Q +S + + E
Sbjct: 531 KDMLEVKER-KINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEA 589
Query: 710 LFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESL 769
L + R +E + E+ E + E L+ ES K+NKDL+ ++L ++ + L
Sbjct: 590 LSEKERIIERLKEQRE---RDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDL 646
Query: 770 KEQNEKSIAQLIEKE----------EQRKEVQNQLVDREHKLANLHQKTKVQEE---KIK 816
KE + ++++ EQ+KE ++L + K N+ +++ E +IK
Sbjct: 647 KEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIK 706
Query: 817 TLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQE 876
L KE + + E+ R +I KE +E +K + ++ E ESL +
Sbjct: 707 QLDKEASYYRDECGKAQAEVDRLLEILKE-------VENEKNDKDKKIAELESLTLRHMK 759
Query: 877 ELNK 880
+ NK
Sbjct: 760 DQNK 763
Score = 55.8 bits (133), Expect = 2e-07
Identities = 69/315 (21%), Positives = 143/315 (45%), Gaps = 32/315 (10%)
Query: 580 SIKCLTPHLKD-GVPGLNIEELIEKLQSGMVVKDQICDVR-ISDIMDVYEMKLSTLASKE 637
SIK L L+ G+P ++E+ E+ + + Q+ + I D + + L +
Sbjct: 304 SIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRR 363
Query: 638 SRLQ-DLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQ 696
S+LQ + +TKAL +T E + +AS+ R + +E+ +L
Sbjct: 364 SQLQPEPAKTKAL---------------QTVIEMKDTKIASLERNIRDLEDEIQMLKANG 408
Query: 697 QVESERAQSDIEHLF---QHNRKLESVAEE-HEILTKSYMELLQ---RNESTEKKNKDLQ 749
+ +E + +I+ + H++ +++ ++ + L+K ELL + E+ +N D +
Sbjct: 409 VLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCK 468
Query: 750 ITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHK-------LA 802
+ L + + ++ L+ + + +L EKE + QL D + +
Sbjct: 469 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIR 528
Query: 803 NLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEG 862
++ +V+E KI LQK+ E+ +E + K+L+ + K L +S+ + A LE
Sbjct: 529 DMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEE 588
Query: 863 RLEEKESLVKLQQEE 877
L EKE +++ +E+
Sbjct: 589 ALSEKERIIERLKEQ 603
Score = 53.5 bits (127), Expect = 9e-07
Identities = 52/222 (23%), Positives = 112/222 (50%), Gaps = 17/222 (7%)
Query: 675 LASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMEL 734
L + L+E++R+N+ L L + + + + I+ + K E V + E S ++
Sbjct: 150 LQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLK- 208
Query: 735 LQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQN-----EKSIAQLIEKEEQRKE 789
++ + ++N+ LQ+T +L ++ T + LN L++++ E +L E+ +R +
Sbjct: 209 -EQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQ 267
Query: 790 VQNQLVDREHKLANLHQKT-KVQEEKIKTLQKEREDKEETIDILRKEL------SRTEQI 842
++ DR+ K L +KT + E +I+T ++ ++E+I L + L S++ +
Sbjct: 268 AEH---DRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLED 324
Query: 843 RKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHM 884
E + + + E Q + LE L++KE +EEL++ S +
Sbjct: 325 DNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQL 366
Score = 52.8 bits (125), Expect = 1e-06
Identities = 50/238 (21%), Positives = 111/238 (46%), Gaps = 23/238 (9%)
Query: 651 LAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHL 710
+ Q D+ + +R + +A+ E L +L+EVE NE+ K ++ES + H+
Sbjct: 705 IKQLDKEASYYRDECGKAQAEVDRLLEILKEVE--NEKNDKDKKIAELES----LTLRHM 758
Query: 711 FQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLK 770
N+K+ ++ ++ K +LL+ E + ++ + +S + QIE + E +
Sbjct: 759 KDQNKKVANLKHNQQLEKKKNAQLLE-----EVRRREDSMADNSQHLQIEELMNALEKTR 813
Query: 771 EQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKER-----EDK 825
++ + + A+L Q L ++E LANL + + Q E+I +++E +K
Sbjct: 814 QELDATKARLAS-------TQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEK 866
Query: 826 EETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSH 883
+ I +L S+ ++ ++E+ + QL+ + + + L+ ++ + H H
Sbjct: 867 DANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYH 924
Score = 50.8 bits (120), Expect = 6e-06
Identities = 49/257 (19%), Positives = 118/257 (45%), Gaps = 10/257 (3%)
Query: 627 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEART--LASMLREVER 684
E + TL +++ ++ LLE + L + R AE E++ L +L + E+
Sbjct: 292 ETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEK 351
Query: 685 KNEEL-SVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILT-KSYMELLQRNESTE 742
+N L L + Q++ E A++ + + + E I + +++L+ N
Sbjct: 352 ENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLN 411
Query: 743 KKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLA 802
++++ +I KQIE K ++ +K + ++ +L +KE + +Q +L ++ +
Sbjct: 412 TEDREEEI------KQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNS 465
Query: 803 NLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEG 862
+ Q +V +E + ++ + +D LR L E + + + L +K L G
Sbjct: 466 DCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAG 525
Query: 863 RLEEKESLVKLQQEELN 879
+ + + ++++++ ++N
Sbjct: 526 EIRDMKDMLEVKERKIN 542
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 66.6 bits (161), Expect = 1e-10
Identities = 70/292 (23%), Positives = 130/292 (44%), Gaps = 44/292 (15%)
Query: 619 ISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASM 678
+ D++DV E K++ L K LQ+ L K ++ + + T +T TL
Sbjct: 562 LKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEA 621
Query: 679 LREVER---------------KNEELS-------------VLLKAQQVESERAQSDI-EH 709
L E ER K EE+ LL+ E E + D+ EH
Sbjct: 622 LAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEH 681
Query: 710 ---LFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLN 766
L K +S + EI + E + ES KK + + + + + ++ L
Sbjct: 682 ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLE 741
Query: 767 ESL---KEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQ-KER 822
+ K+++ K+ A++ E KEV+N+ D++ K+A L ++ K Q +K+ L+ KE+
Sbjct: 742 REITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQ 801
Query: 823 EDKEETIDILRKELSRTEQIRKELSIKASSLEVQKA--QLEGRLEEKESLVK 872
+K+++ +L E R+E ++ SS ++Q + + + R+EE E ++
Sbjct: 802 VEKKKSAQMLE------EARRREDNLNDSSQQLQDSLRKKDDRIEELEEALR 847
Score = 64.7 bits (156), Expect = 4e-10
Identities = 72/366 (19%), Positives = 158/366 (43%), Gaps = 31/366 (8%)
Query: 554 NAYRQQETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGL-NIEELIEKLQSGMVVKD 612
N+ ++E P + + T I+ + GL ++EE I+ L+S +
Sbjct: 357 NSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALST 416
Query: 613 QICDVRISDIMDVY-----------EMKLSTLASKESRLQDLLETKA---LALAQADRLI 658
+ + + M+VY E L+SKE++ ++L + A + Q + +
Sbjct: 417 EEREEEMKQ-MEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQEL 475
Query: 659 AQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLF------- 711
++ + +T+ TL + + ++ E L L A++ + Q++++ L
Sbjct: 476 SRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKE 535
Query: 712 ----QHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNE 767
+ ++++ +AEE +L + E+K LQ ++L +Q+ +K
Sbjct: 536 TMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS 595
Query: 768 SLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKT----KVQEEKIKTLQKERE 823
SLKE+ + A + ++ L ++E + L ++ + ++E+I +K+ +
Sbjct: 596 SLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLK 655
Query: 824 DKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSH 883
D +E + +L+ +LS E +L ASSL + + RL+ E ++ ++EE K
Sbjct: 656 DLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMES 715
Query: 884 MIAMIH 889
+ H
Sbjct: 716 QLKKAH 721
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/302 (22%), Positives = 137/302 (45%), Gaps = 26/302 (8%)
Query: 594 GLNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKE--SRLQDL-------L 644
GL + ++ L+ + K + C S + +E L AS E R+Q L
Sbjct: 689 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK 748
Query: 645 ETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQ 704
+ + A A+ DRL+ + + + + +A + R+V+ +N++++ L +QVE +++
Sbjct: 749 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA 808
Query: 705 SDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKK-NKDLQITCDSLNKQIETVK 763
+E + R+ +++ + + L S + R E E+ + +QIT + E V
Sbjct: 809 QMLE---EARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAER-----EMVL 860
Query: 764 KLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKERE 823
ES + EK + +L+ E +V+ +L + KL++ Q +E + L+ ER
Sbjct: 861 AQEESARTNAEKQVEELLMAME---KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERR 917
Query: 824 DKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRL----EEKESLV-KLQQEEL 878
E + +++E K+ +I L K + + + EK+ LV +L+Q+
Sbjct: 918 KHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQ 977
Query: 879 NK 880
N+
Sbjct: 978 NR 979
Score = 52.0 bits (123), Expect = 2e-06
Identities = 74/339 (21%), Positives = 142/339 (41%), Gaps = 62/339 (18%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL 657
E + + V + R + IMD+ + +L + + L+ +E K L+ +
Sbjct: 127 EHHLPPVSMASTVPHSLRQARDNTIMDL-QTQLKEVLRENDLLRKDVEVKESKLSSSMNS 185
Query: 658 IA--------QHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEH 709
I + R R ++ R V+ +N+ + + ++A Q E R Q D+
Sbjct: 186 IKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDEL-RIQRDLNQ 244
Query: 710 LFQHNRKLES----VAE-----------EHEILTKSYMELLQRNESTEKKNKDLQITCDS 754
LFQ + + VAE EHE K EL ++ E+ ++ +
Sbjct: 245 LFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAK---ELFLLRKTLEEMELRIETQKQT 301
Query: 755 LNKQIETVKKLNESLK----------EQNEKS------------IAQLIEKEEQRKEVQN 792
LN + E++KKL E L+ E +E++ + L+E++E+ +
Sbjct: 302 LNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLR 361
Query: 793 QLVDREHKLANLHQKTK-------VQEEKIKTLQKEREDKEETIDILRK----ELSRTEQ 841
+ + R + A KTK +++ KI ++++ D EE I +L+ E+
Sbjct: 362 EEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREE 421
Query: 842 IRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
K++ + S + K ++E +L+E+ S + Q EEL K
Sbjct: 422 EMKQMEVYRSHSKFMKNKVE-QLKEELSSKEAQWEELKK 459
Score = 50.4 bits (119), Expect = 7e-06
Identities = 65/283 (22%), Positives = 117/283 (41%), Gaps = 41/283 (14%)
Query: 623 MDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREV 682
+D Y+ L L K S LQ L K +L + + ++ +TL L
Sbjct: 647 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIAL--- 703
Query: 683 ERKNEEL----SVLLKAQQVESERAQSD-----IEHLFQHNRKLESVAEEHEILTKSYME 733
E+K EE S L KA + E S I+HL + + + + + + +E
Sbjct: 704 EQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLE 763
Query: 734 LLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQ 793
+L+ E+ EK +KD +I +L +K+QN+K +A L KE+ K+ Q
Sbjct: 764 ILKEVEN-EKNDKDKKIA------------ELERQVKDQNKK-VANLKHKEQVEKKKSAQ 809
Query: 794 LVDREHKLA-NLHQKTKVQEEKIKTLQKEREDKEETID-----------ILRKELSRTEQ 841
+++ + NL+ ++ ++ ++ E+ EE + +L +E S
Sbjct: 810 MLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTN 869
Query: 842 IRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHM 884
K++ ++E K +LE K L QQ K +H+
Sbjct: 870 AEKQVEELLMAMEKVKQELESM---KAKLSSTQQSLAEKETHL 909
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 66.6 bits (161), Expect = 1e-10
Identities = 70/292 (23%), Positives = 130/292 (44%), Gaps = 44/292 (15%)
Query: 619 ISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASM 678
+ D++DV E K++ L K LQ+ L K ++ + + T +T TL
Sbjct: 534 LKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEA 593
Query: 679 LREVER---------------KNEELS-------------VLLKAQQVESERAQSDI-EH 709
L E ER K EE+ LL+ E E + D+ EH
Sbjct: 594 LAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEH 653
Query: 710 ---LFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLN 766
L K +S + EI + E + ES KK + + + + + ++ L
Sbjct: 654 ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLE 713
Query: 767 ESL---KEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQ-KER 822
+ K+++ K+ A++ E KEV+N+ D++ K+A L ++ K Q +K+ L+ KE+
Sbjct: 714 REITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQ 773
Query: 823 EDKEETIDILRKELSRTEQIRKELSIKASSLEVQKA--QLEGRLEEKESLVK 872
+K+++ +L E R+E ++ SS ++Q + + + R+EE E ++
Sbjct: 774 VEKKKSAQMLE------EARRREDNLNDSSQQLQDSLRKKDDRIEELEEALR 819
Score = 62.4 bits (150), Expect = 2e-09
Identities = 65/314 (20%), Positives = 133/314 (42%), Gaps = 46/314 (14%)
Query: 622 IMDVYEMKLSTLASKESRLQDLLE-------TKALALAQADRLIAQHRCQRTQAETEART 674
+ V EMK S ++S E L+DL E AL+ + + + Q R+ ++
Sbjct: 380 LQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNK 439
Query: 675 LASMLREVERKNEELSVL------------------------LKAQQVESERAQSDIEHL 710
+ + +E+ RK+ EL L L A++ + Q++++ L
Sbjct: 440 IGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDAL 499
Query: 711 F-----------QHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQI 759
+ ++++ +AEE +L + E+K LQ ++L +Q+
Sbjct: 500 RLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQL 559
Query: 760 ETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKT----KVQEEKI 815
+K SLKE+ + A + ++ L ++E + L ++ + ++E+I
Sbjct: 560 RDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEI 619
Query: 816 KTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQ 875
+K+ +D +E + +L+ +LS E +L ASSL + + RL+ E ++ ++
Sbjct: 620 DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKK 679
Query: 876 EELNKHSHMIAMIH 889
EE K + H
Sbjct: 680 EECLKMESQLKKAH 693
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/302 (22%), Positives = 137/302 (45%), Gaps = 26/302 (8%)
Query: 594 GLNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKE--SRLQDL-------L 644
GL + ++ L+ + K + C S + +E L AS E R+Q L
Sbjct: 661 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK 720
Query: 645 ETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQ 704
+ + A A+ DRL+ + + + + +A + R+V+ +N++++ L +QVE +++
Sbjct: 721 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA 780
Query: 705 SDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKK-NKDLQITCDSLNKQIETVK 763
+E + R+ +++ + + L S + R E E+ + +QIT + E V
Sbjct: 781 QMLE---EARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAER-----EMVL 832
Query: 764 KLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKERE 823
ES + EK + +L+ E +V+ +L + KL++ Q +E + L+ ER
Sbjct: 833 AQEESARTNAEKQVEELLMAME---KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERR 889
Query: 824 DKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRL----EEKESLV-KLQQEEL 878
E + +++E K+ +I L K + + + EK+ LV +L+Q+
Sbjct: 890 KHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQ 949
Query: 879 NK 880
N+
Sbjct: 950 NR 951
Score = 50.4 bits (119), Expect = 7e-06
Identities = 65/283 (22%), Positives = 117/283 (41%), Gaps = 41/283 (14%)
Query: 623 MDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREV 682
+D Y+ L L K S LQ L K +L + + ++ +TL L
Sbjct: 619 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIAL--- 675
Query: 683 ERKNEEL----SVLLKAQQVESERAQSD-----IEHLFQHNRKLESVAEEHEILTKSYME 733
E+K EE S L KA + E S I+HL + + + + + + +E
Sbjct: 676 EQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLE 735
Query: 734 LLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQ 793
+L+ E+ EK +KD +I +L +K+QN+K +A L KE+ K+ Q
Sbjct: 736 ILKEVEN-EKNDKDKKIA------------ELERQVKDQNKK-VANLKHKEQVEKKKSAQ 781
Query: 794 LVDREHKLA-NLHQKTKVQEEKIKTLQKEREDKEETID-----------ILRKELSRTEQ 841
+++ + NL+ ++ ++ ++ E+ EE + +L +E S
Sbjct: 782 MLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTN 841
Query: 842 IRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHM 884
K++ ++E K +LE K L QQ K +H+
Sbjct: 842 AEKQVEELLMAMEKVKQELESM---KAKLSSTQQSLAEKETHL 881
Score = 47.0 bits (110), Expect = 8e-05
Identities = 70/342 (20%), Positives = 144/342 (42%), Gaps = 63/342 (18%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL 657
E + + V + R + IMD+ + +L + + L+ +E K L+ +
Sbjct: 127 EHHLPPVSMASTVPHSLRQARDNTIMDL-QTQLKEVLRENDLLRKDVEVKESKLSSSMNS 185
Query: 658 IA--------QHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEH 709
I + R R ++ R V+ +N+ + + ++A Q E R Q D+
Sbjct: 186 IKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDEL-RIQRDLNQ 244
Query: 710 LFQHNRKLES----VAE-----------EHEILTKSYMELLQRNESTEKKNKDLQITCDS 754
LFQ + + VAE EHE K EL ++ E+ ++ +
Sbjct: 245 LFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAK---ELFLLRKTLEEMELRIETQKQT 301
Query: 755 LNKQIETVKKLNESLK----------EQNEKS------------IAQLIEKEEQRKEVQN 792
LN + E++KKL E L+ E +E++ + L+E++E+ +
Sbjct: 302 LNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLR 361
Query: 793 QLVDREHKLANLHQKTK-------VQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKE 845
+ + R + A KTK +++ KI ++++ D EE I +L+ + + + R+E
Sbjct: 362 EEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREE 421
Query: 846 LSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAM 887
+ +EV ++ + K + +++QE K + ++A+
Sbjct: 422 ---EMKQMEVYRSHSKFM---KNKIGQVKQELSRKDTELLAL 457
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 66.2 bits (160), Expect = 1e-10
Identities = 54/243 (22%), Positives = 113/243 (46%), Gaps = 20/243 (8%)
Query: 634 ASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLL 693
AS+E R ++ LE K L QAD +TE + L +++ + + ++L L
Sbjct: 211 ASREFRKKEKLE-KELKQIQADM---------DSRQTEIKALQQYVQKSKEELQKLEQQL 260
Query: 694 KAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCD 753
K Q++ +ERA ++E N KL+ E+H ++ + +L Q N+ + K +
Sbjct: 261 KEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCE---QLSQENQQKALELKAKEEEVH 317
Query: 754 SLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEE 813
+ I + K+ E + ++ + Q E E+ ++ ++NQ+V E ++ ++ ++ +
Sbjct: 318 QMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRK 377
Query: 814 KIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKL 873
+ L +ER DIL K + + ++ + E K LEG ++ + +
Sbjct: 378 AMDELLRER-------DILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQK 430
Query: 874 QQE 876
Q++
Sbjct: 431 QRK 433
Score = 52.8 bits (125), Expect = 1e-06
Identities = 69/280 (24%), Positives = 128/280 (45%), Gaps = 45/280 (16%)
Query: 617 VRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETE--ART 674
VR + I D Y K++ K + Q+L E ++DR + Q E R
Sbjct: 465 VRETQIFD-YRKKIAESEIKLKQQQNLYEA-----VRSDRNLYSKNLVEAQDEITDMKRK 518
Query: 675 LASMLREVERKNEELSV---LLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSY 731
L M+ +V+ E++S L +E +R + + E L +KL A E TK +
Sbjct: 519 LKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALE----TKHF 574
Query: 732 MELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQ 791
+E + E+ E+K L+I ++ +++ K+L++ + E R +
Sbjct: 575 IE---KQEAEERKL--LRIIAEADGERLRQKKELDQVISE---------------RDILG 614
Query: 792 NQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKAS 851
+QLV R +LA L++K K+Q+ + + + + E + ILR E+ +++R+E I A
Sbjct: 615 SQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILRLEI---KKLRREKGILAR 671
Query: 852 SLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSL 891
S+ A +E E ++ +Q+E L + + A+ L
Sbjct: 672 SM----ANVE---ELRQEFFHMQRELLKERTRCRALEEEL 704
Score = 43.5 bits (101), Expect = 9e-04
Identities = 47/222 (21%), Positives = 97/222 (43%), Gaps = 21/222 (9%)
Query: 668 AETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
++ + T+AS+ +E+E+ + + +Q E + E + + +E +
Sbjct: 85 SQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQ 144
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
+ +LL+ E K+ L + V KL ESL + E+ KEE
Sbjct: 145 HSNIRDLLRFKEEVTKERDQL----------LSEVVKLRESLAQTTEQQQETERSKEEAE 194
Query: 788 KEV---QNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRK 844
+ Q ++ R+++ + +K + E+++K +Q + + ++ I L++ + ++ ++
Sbjct: 195 HAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKS---KE 251
Query: 845 ELSIKASSLEVQKAQLEGRLEEKESL----VKLQQEELNKHS 882
EL L+ QK E +E E KLQQE +HS
Sbjct: 252 ELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQEN-EQHS 292
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 65.9 bits (159), Expect = 2e-10
Identities = 53/250 (21%), Positives = 120/250 (48%), Gaps = 14/250 (5%)
Query: 653 QADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESE---RAQSDIEH 709
Q ++ Q R Q E M R+ E+ +E+ + + ++ E E R + I
Sbjct: 475 QEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 534
Query: 710 LFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESL 769
+ R+ E + E+ E + K ++ ++ E + + ++ + + +Q E +++ E +
Sbjct: 535 QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKI 594
Query: 770 KEQNEKSIAQ----------LIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQ 819
+EQ EK Q + E+EE+ E + ++ ++E K+ +K + QE+KI+ +
Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654
Query: 820 KEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELN 879
++ ++EE + +++ E+ E K E + + E ++ E+E ++ Q+E++
Sbjct: 655 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
Query: 880 KH-SHMIAMI 888
+H H+ A I
Sbjct: 715 EHQEHLEAAI 724
Score = 65.5 bits (158), Expect = 2e-10
Identities = 62/278 (22%), Positives = 125/278 (44%), Gaps = 40/278 (14%)
Query: 640 LQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVE 699
L+ L A +ADR I + +R E E++ KN +L K Q VE
Sbjct: 238 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE--KLQLVE 295
Query: 700 SERA-------------------------QSDIEHLFQH----NRKLESVAEEHEILTKS 730
SE++ Q++ +HL + + KL++ EE+E+ +
Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 355
Query: 731 YMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQ---LIEKEEQR 787
Q+ E ++ + +Q + + +Q E +++ E ++EQ EK Q + EKEE+
Sbjct: 356 NQ---QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELS 847
+ + + ++E K+ + +EEKI+ L+++ ++E+ I +E R E+ +
Sbjct: 413 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK---IREQEEKRQEEEKIREQ 469
Query: 848 IKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
K E + + E ++ E+E ++ Q+E++ + I
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507
Score = 64.7 bits (156), Expect = 4e-10
Identities = 44/228 (19%), Positives = 110/228 (48%), Gaps = 14/228 (6%)
Query: 661 HRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQV---ESERAQSDIEHLFQHNRKL 717
H ++ + + E R +RE E++ E+ + + + ++ + E+ + E +++ K+
Sbjct: 448 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507
Query: 718 ESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSI 777
+ E + E + R E ++ +++ + +++Q E ++K E + Q EK
Sbjct: 508 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK-- 565
Query: 778 AQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELS 837
+ ++EE+ +E +E K+ +K + QEEKI+ +++ ++EE +++
Sbjct: 566 --MHDQEEKIRE-------QEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616
Query: 838 RTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
E+ E K E + + E ++ E+E ++ Q+E++ + M+
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664
Score = 64.3 bits (155), Expect = 5e-10
Identities = 54/288 (18%), Positives = 137/288 (47%), Gaps = 13/288 (4%)
Query: 597 IEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADR 656
I EL EK+ +++Q + + + E + A + + + E + Q ++
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Query: 657 LIAQ----HRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQV--ESERAQSDIEHL 710
+ Q H ++ + E + + M R+ E+ E+ + + +++ + E+ + E +
Sbjct: 500 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKM 559
Query: 711 FQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLK 770
++ K+ ++ E + + ++ ++ E ++ + ++ + + +Q E ++ E +
Sbjct: 560 WRQEEKMH---DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616
Query: 771 EQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETID 830
EQ EK + E+EE+ +E + ++ +E K+ +K + QEEKI+ ++ +++EE +
Sbjct: 617 EQEEK----MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 672
Query: 831 ILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 878
+++ E+ +E K E + + E RL ++E ++ QE L
Sbjct: 673 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 62.8 bits (151), Expect = 1e-09
Identities = 50/232 (21%), Positives = 113/232 (48%), Gaps = 15/232 (6%)
Query: 667 QAETEARTLASMLREVERKNEELSVLLKAQQV--ESERAQSDIEHLFQHNRKLESVAE-- 722
+ E + R M+ E E K EL + Q+ E E + + E + + ++ E A+
Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 480
Query: 723 -------EHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNE- 774
E E + E + R E EK ++ +I + ++ E + + E ++EQ E
Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQE--EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Query: 775 -KSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILR 833
+ ++ E+EE+ ++ + ++ +E K+ + +K + QEEK+ +++ ++EE I
Sbjct: 539 WRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Query: 834 KELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
+++ E++ +E K E + + E +++E+E ++ Q+E++ + I
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKI 650
Score = 58.9 bits (141), Expect = 2e-08
Identities = 58/302 (19%), Positives = 141/302 (46%), Gaps = 18/302 (5%)
Query: 597 IEELIEKLQ--SGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQA 654
IEEL ++ S + ++ I D + + + KL + S++S +Q ++ L +A
Sbjct: 256 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 315
Query: 655 DRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHN 714
L+ Q + Q +A+ + L S+ +++ + EE + + Q + E+ E + +
Sbjct: 316 KLLLPQQQLQ-AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 374
Query: 715 RKL-----------ESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVK 763
K+ E + E+ E + + + ++ E ++ + + + + +Q E +
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 764 KLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKERE 823
+ E ++E EK Q +E++ K + + + + K K QEEKI+ +++
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 824 DKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSH 883
++EE + +++ E+IR+E + + + + E ++ E+E + + Q+E++++
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREE---EKRQEQEEMWRQEEKIREQEEIWR-QKEKIHEQEE 550
Query: 884 MI 885
I
Sbjct: 551 KI 552
Score = 55.1 bits (131), Expect = 3e-07
Identities = 57/231 (24%), Positives = 111/231 (48%), Gaps = 23/231 (9%)
Query: 667 QAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLES----VAE 722
+ E +A+ ++ +R EEL+ A +E R E L + N KL+ V
Sbjct: 237 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 296
Query: 723 EHEILTKSYMELLQRNESTE--KKNKDLQITCDSLNKQIETVK-KLNESLKEQ------N 773
E + + EL ++ E + + LQ D L K++++V KL ++E N
Sbjct: 297 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 356
Query: 774 EKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQK---EREDK----E 826
++ ++ +EE+ +E + ++ ++E K+ +K + QEEK++ ++ E+E+K E
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 416
Query: 827 ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEE 877
E + +++ R E++ E K LE + + E E++E K Q+EE
Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE---KRQEEE 464
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 65.9 bits (159), Expect = 2e-10
Identities = 68/315 (21%), Positives = 145/315 (46%), Gaps = 34/315 (10%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL 657
+++ ++L++ M + ++ I+ +E+ + E L+D + L L + D+
Sbjct: 715 DKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRT---EKALKDQINQLELLLKERDKH 771
Query: 658 IAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKL 717
+ +H+ E + + L++ K L V Q E+ ++ E L Q +KL
Sbjct: 772 LKEHQAHVENLEADIKRSEGELQQASAK---LDVFQSYQSATHEQTKAYEEQLAQLQQKL 828
Query: 718 ESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNE---SLKEQNE 774
+ E +LTK E+ E + KD+ D+ Q++ + + E S EQ
Sbjct: 829 LDLETERILLTKQVAEV-------EAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKV 881
Query: 775 KSIAQLIEKE-----EQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETI 829
KS+ Q+ E + +++++ + LV++E+ + + + Q+++I+ L ++ KE++I
Sbjct: 882 KSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREG---QKKEIEILTQKLSAKEDSI 938
Query: 830 DILRKELSR--TEQIRKELSIKASSLEVQKAQLEGRLEEKESLVK--------LQQEELN 879
IL +E Q +K +K + E+Q+ + L+++ L K L Q+E
Sbjct: 939 HILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQ 998
Query: 880 KHSHMIAMIHSLSGG 894
++ M+ M + S G
Sbjct: 999 FNAKMLEMAQANSAG 1013
Score = 62.8 bits (151), Expect = 1e-09
Identities = 61/294 (20%), Positives = 139/294 (47%), Gaps = 26/294 (8%)
Query: 597 IEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASK-ESRLQDLLETKALALA--- 652
+E+ +L+S +D + ++ + Y+ ++ L K E + LL+ K +
Sbjct: 609 VEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHI 668
Query: 653 --QADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLL-KAQQVESERAQSDIEH 709
++ + + ++T+ E+ + L+ +L+ + EELSVL + +++ E E
Sbjct: 669 EEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQ 728
Query: 710 LFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESL 769
H ++++S+ +EHE+ +QR E K D +N+ +K+ ++ L
Sbjct: 729 KNHHQQQVDSIIKEHEVS-------IQRTEKALK---------DQINQLELLLKERDKHL 772
Query: 770 KEQN---EKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKE 826
KE E A + E + ++ +L + + H++TK EE++ LQ++ D E
Sbjct: 773 KEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLE 832
Query: 827 ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
+L K+++ E +K++ + + ++Q L +LE++ S ++ + + L +
Sbjct: 833 TERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 886
Score = 57.8 bits (138), Expect = 5e-08
Identities = 76/304 (25%), Positives = 146/304 (48%), Gaps = 54/304 (17%)
Query: 622 IMDVYEMKLSTL----ASKESRLQDLLETKALALAQ--------ADRLIAQHRCQRTQAE 669
+ YE K+S L KE LQ + + K ++ +RLI + Q E
Sbjct: 1730 VQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHE 1789
Query: 670 TEARTLASMLREVERKNEELSVLLKAQQVESE------RAQSDIEHLFQHNRKLESVAEE 723
++ + + E+E KN++ S+++ AQ VE E +A+ ++E++F +K +E
Sbjct: 1790 DQSM-IGHLQEELEEKNKKYSLIV-AQHVEKEGGKNNIQAKQNLENVFDDVQK---TLQE 1844
Query: 724 HEILTKSYMELLQRNESTEKKNKDL-QITCDSLNKQIETVKKLNE--------SLKEQN- 773
E+ + + ++ +S + K++ ++ + L + E ++ L + L E+N
Sbjct: 1845 KELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENT 1904
Query: 774 -EKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKE----REDKEET 828
EKS + L++ + ++ Q D E KLA ++ + ++I LQK+ R++ ++
Sbjct: 1905 EEKSKSHLVQPK-LLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQE 1963
Query: 829 IDILRKEL--SRTEQIRKE---LSIKASS--------LEVQKAQLEGRLEE--KESLVKL 873
++IL+KE R E+I++E L +K +S Q AQ E LE KE++ K
Sbjct: 1964 LEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKA 2023
Query: 874 QQEE 877
Q+ E
Sbjct: 2024 QEVE 2027
Score = 56.6 bits (135), Expect = 1e-07
Identities = 84/349 (24%), Positives = 142/349 (40%), Gaps = 36/349 (10%)
Query: 560 ETEHIPRKMPWQSSNHSFPTSIKCLTPH---LKDGVPGLNIEELIEKLQSGMVVKDQICD 616
E E KM + SN T +K T L+D + IE IE L + +Q D
Sbjct: 1501 EMEDDKSKMEKKESN--LETELKSQTARIMELEDHITQKTIE--IESLNEVLKNYNQQKD 1556
Query: 617 VRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLA 676
+ +++ + K++R+++ E K L L Q + + ET+ + L
Sbjct: 1557 IEHKELVQKLQHFQELGEEKDNRVKEA-EEKILTLEN------QVYSMKAELETKKKELE 1609
Query: 677 SMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQ 736
+ V+ K EEL L ++ESE A E + +K+ ++ ++ L Q
Sbjct: 1610 HVNLSVKSKEEELKAL--EDRLESESAAKLAELKRKAEQKIAAIKKQL---------LSQ 1658
Query: 737 RNESTEKKNKDLQITCDSLNKQIETVKK----LNESLKEQNEKSIAQLIEKEEQRKEVQN 792
E E+ K + LN +++ ++ L E LK E S ++ + K V
Sbjct: 1659 MEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSV-ESSQSETLIVPRSAKNVAA 1717
Query: 793 QLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASS 852
E QKT EEKI LQ+ +KE+ + + +E T E+ +
Sbjct: 1718 YTEQEEADSQGCVQKT--YEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQE 1775
Query: 853 LEVQKAQLEGRLEEKESLVKLQQEEL----NKHSHMIAMIHSLSGGKIN 897
++ E + E +S++ QEEL K+S ++A GGK N
Sbjct: 1776 RLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNN 1824
Score = 51.2 bits (121), Expect = 4e-06
Identities = 54/222 (24%), Positives = 106/222 (47%), Gaps = 22/222 (9%)
Query: 680 REVERKNEELSVLLKAQQVE-SERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRN 738
+E+ RK +EL+ L+ ++ E E+ + +E K+ E+ E L +EL ++
Sbjct: 487 KELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKA 546
Query: 739 ESTEKKNK--DLQITCDSLNKQI-ETVKKLNESLKEQNEKSIAQLI----EKEEQRKEVQ 791
TE +NK DLQ ++ +I E L +SL+E +S + EK + KE+
Sbjct: 547 ILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEIT 606
Query: 792 NQLVDREHKLANL-HQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKA 850
+ + +L +L HQ+ + EK++ L+++ + + E + ++ T KE+ +A
Sbjct: 607 VMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQA 666
Query: 851 ----------SSLEVQKAQLEGRLEEKESLVKLQ---QEELN 879
L+V++ +LE E ++K + +EEL+
Sbjct: 667 HIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELS 708
Score = 49.3 bits (116), Expect = 2e-05
Identities = 78/324 (24%), Positives = 133/324 (41%), Gaps = 41/324 (12%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKAL---ALAQA 654
E+L E+LQ +KD + I + + K ++ + + ETK L
Sbjct: 321 EQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMK 380
Query: 655 DRLIAQHRCQRTQAETEARTLASMLREVERKN-EELSVLLKAQQVESERAQSDIEHLFQH 713
+ IAQ R + Q T+ L + ER EEL L Q E + + +
Sbjct: 381 EEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQ 440
Query: 714 NRKLESVAEEHEI-LTKSYMELLQRNESTEKKNKDLQITC-------DSLNKQIETVKKL 765
+ +E +EE I L + + Q KK+ + QI + K+ E KKL
Sbjct: 441 IKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKL 500
Query: 766 N-------ESLKEQNEKSIAQLI----EKEEQRK------EVQNQ--LVDREHKLANLHQ 806
E +K EKS ++ + EKE+Q E+Q + L + E+KL +L Q
Sbjct: 501 QTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQ 560
Query: 807 KTKVQEEKIKTLQKE-----REDKEETIDILRKELSRTEQIRKELSIKA----SSLEVQK 857
+ + +I L+ +E+K ++ D+ + + KE+++ + LE K
Sbjct: 561 EAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLK 620
Query: 858 AQLEGRLEEKESLVKLQ-QEELNK 880
Q + EK ++K Q Q E+ K
Sbjct: 621 HQQDALWTEKLQVLKQQYQTEMEK 644
Score = 48.1 bits (113), Expect = 4e-05
Identities = 67/295 (22%), Positives = 125/295 (42%), Gaps = 54/295 (18%)
Query: 624 DVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQA------------ETE 671
++ E L +E++L+ LE AL L+Q ++ + QA ET
Sbjct: 965 EMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETN 1024
Query: 672 ARTLASMLREVERK--NEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTK 729
+ L EV R+ N+ +S+ K ++E Q H Q K + VAE +
Sbjct: 1025 QKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEI--HEIQLQEKEQEVAELKQ---- 1078
Query: 730 SYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKE---------QNEKSIAQL 780
++L E+ NK++ + KQ T+ +L E LK+ Q+E +
Sbjct: 1079 ---KILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH 1135
Query: 781 IEKEE--------QRKEVQNQLVDRE-------HKLANLHQKTKVQEEKIKTLQKEREDK 825
+EK E + +Q QLV+ + K++ L K K +E+ ++L+ E
Sbjct: 1136 LEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKS 1195
Query: 826 EETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEK-ESLVKLQQEELN 879
++++ E +++ +EL+I+ L++ + E LE K L+ + + N
Sbjct: 1196 NKSLEDKSLEF---KKLSEELAIQ---LDICCKKTEALLEAKTNELINISSSKTN 1244
Score = 46.6 bits (109), Expect = 1e-04
Identities = 67/296 (22%), Positives = 126/296 (42%), Gaps = 34/296 (11%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL 657
EEL +L + + + + ++++++ K + + S+ S Q AL
Sbjct: 1211 EELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCT 1270
Query: 658 IAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKL 717
+++ Q Q E TL ++ + EE K Q++S +A +
Sbjct: 1271 VSELEAQLRQLTEEQNTLNISFQQATHQLEE-----KENQIKSMKAD------------I 1313
Query: 718 ESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSI 777
ES+ E E L K Q+ ++EK++ Q+ + L++ I V + E LKE+ +
Sbjct: 1314 ESLVTEKEALQKEGGN--QQQAASEKESCITQLKKE-LSENINAVTLMKEELKEKKVEIS 1370
Query: 778 AQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKE-L 836
+ + + ++QN + E + A + + EEK + L + +D +D L KE +
Sbjct: 1371 SLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLD-QVQDLSFKVDTLSKEKI 1429
Query: 837 SRTEQIR------KELSIKASSL------EVQKAQLEGRLEEKESLVKLQQEELNK 880
S EQ+ E KA S V++ Q++ L+ KE+ K +Q L K
Sbjct: 1430 SALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLK 1485
Score = 44.3 bits (103), Expect = 5e-04
Identities = 44/177 (24%), Positives = 86/177 (48%), Gaps = 23/177 (12%)
Query: 660 QHRCQRTQAETEAR---TLASMLRE----VERKNEELSVLLK-----AQQVESERAQSDI 707
+ + ++ Q + E + TL ++RE + +K +EL + +K AQ+VE+E +S
Sbjct: 1976 EEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLES-- 2033
Query: 708 EHLFQHNRKLESVAEEHEIL---TKSYMELLQ-RNESTEKKNKDLQITCDSLNKQIETVK 763
H + N+ L+ +AE+ + L K Y E+L R E K +DLQ + L K+ + +
Sbjct: 2034 -HQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQ--Q 2090
Query: 764 KLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQK 820
KL + N+ ++E + Q + + D + K ++ E+++K +K
Sbjct: 2091 KLEQEENPGNDN--VTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2145
Score = 42.0 bits (97), Expect = 0.003
Identities = 59/258 (22%), Positives = 110/258 (42%), Gaps = 30/258 (11%)
Query: 629 KLSTLASKESRLQDLLETKALALAQADRLIAQHR---CQRTQAETEARTLASMLREVERK 685
+ +L S + LE K+L + +A C++T+A EA+T
Sbjct: 1184 EFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKT----------- 1232
Query: 686 NEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMEL-LQRNESTEKK 744
NE +++ S + + + + + V E I T + EL Q + TE++
Sbjct: 1233 NELINI-------SSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQ 1285
Query: 745 NKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANL 804
N L I+ Q+E + +S+K E + EKE +KE NQ K + +
Sbjct: 1286 NT-LNISFQQATHQLEEKENQIKSMKADIESLVT---EKEALQKEGGNQQQAASEKESCI 1341
Query: 805 HQKTKVQEEKIKT---LQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLE 861
Q K E I +++E ++K+ I L K+L+ ++ + SI S E + L
Sbjct: 1342 TQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDL-NVQLQNSISLSEKEAAISSLR 1400
Query: 862 GRLEEKESLVKLQQEELN 879
+ +E++ + Q ++L+
Sbjct: 1401 KQYDEEKCELLDQVQDLS 1418
Score = 39.3 bits (90), Expect = 0.017
Identities = 47/210 (22%), Positives = 83/210 (39%), Gaps = 40/210 (19%)
Query: 708 EHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQ-ITCDSLNKQIETVKKLN 766
E L Q R++E + Y EL+ + +++ K LQ I S +K + + +L
Sbjct: 137 EQLIQRLRRMERSLSSYR---GKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELR 193
Query: 767 ESL-------KEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQ------EE 813
E L K E+ A L EK++ +Q Q+ + +L N V E
Sbjct: 194 EELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEP 253
Query: 814 KIKTLQKEREDKEE------------TIDILRKELSRTEQIRK-----------ELSIKA 850
+ + KE + + T++ L++ + R E + K + ++
Sbjct: 254 QAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLT 313
Query: 851 SSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
S E + QL+ RL+E E + L E K
Sbjct: 314 SEKEALQEQLDERLQELEKIKDLHMAEKTK 343
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 65.5 bits (158), Expect = 2e-10
Identities = 52/232 (22%), Positives = 112/232 (48%), Gaps = 22/232 (9%)
Query: 658 IAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKL 717
+ Q Q+ AE A L L+E ER+ EE+ ++ + E E AQ D++ F K
Sbjct: 469 LQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV--AKE 526
Query: 718 ESVAEEHEILTKSYM-------ELLQRNESTEKK-NKDLQITCDSLNKQIETVKKLNESL 769
V H LT + + L+Q ES +K+ NK+ +SL Q++ + + NE+L
Sbjct: 527 NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKE-----ESLQMQVQDILEQNEAL 581
Query: 770 KEQNEKSIAQLIEKEEQ---RKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKE 826
K Q ++ +Q+ + +E+ + +++ ++ + +++ + ++E +D +
Sbjct: 582 KAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQ 641
Query: 827 ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 878
+L+ E+ + + + E + A LE +++ + K+ ++L +E+L
Sbjct: 642 NMNFLLKAEVQKLQALANEQAAAAHELE----KMQQSVYVKDDKIRLLEEQL 689
Score = 61.6 bits (148), Expect = 3e-09
Identities = 70/306 (22%), Positives = 137/306 (44%), Gaps = 21/306 (6%)
Query: 571 QSSNHSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKL 630
++ N S ++ L D V + L+E+L+ + KD +I + ++ E +L
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQV---SFASLVEELKKVIHEKDG----KIKSVEELLEAEL 821
Query: 631 STLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELS 690
+A+KE +Q + +K L + E + T+ ++L E E+
Sbjct: 822 LKVANKEKTVQLSITSKVQELQNLLK----------GKEEQMNTMKAVLEEKEKDLANTG 871
Query: 691 VLLKAQQVESERAQSDIEHLFQHNRKLESVA---EEHEILTKSYMELLQRNESTEKKNKD 747
L+ Q E+E ++ ++ + QHN K S A EE EI+ K L+R E+ K+ +
Sbjct: 872 KWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERES 931
Query: 748 LQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQK 807
+ L + ++ KL +S EQ ++ Q +E+ + +RE +++ L +
Sbjct: 932 DLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNE 991
Query: 808 TKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEK 867
++ ++ +K+ D E + L+ TE++ ++ + +S E Q+ LE K
Sbjct: 992 LDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQD-KVNKTSKERQQQVEAVELEAK 1050
Query: 868 ESLVKL 873
E L KL
Sbjct: 1051 EVLKKL 1056
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/297 (22%), Positives = 137/297 (46%), Gaps = 23/297 (7%)
Query: 597 IEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADR 656
++ L KL +V K Q+ + R+ +M+ + +++ S + ++QD+LE AQ +
Sbjct: 529 VQSLHSKLTDTLVSKQQL-EQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQ 587
Query: 657 LIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQ---VESERAQSDIEH---- 709
+Q Q T A A L ++ E +++ ++ L +++ E DI++
Sbjct: 588 FHSQIAAQ-TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL 646
Query: 710 LFQHNRKLESVAEE-----HEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKK 764
L +KL+++A E HE L K + +++ + LQ + ++ + +
Sbjct: 647 LKAEVQKLQALANEQAAAAHE-LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND 705
Query: 765 LNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKERED 824
N++LK + +K Q + E+ K+V Q+ E + +K K EE ++T +
Sbjct: 706 QNKALKSEVQK--LQTLVSEQPNKDVVEQM---EKCIQEKDEKLKTVEELLETGLIQVAT 760
Query: 825 KEETIDILRKELSRTEQIRKELSIKAS---SLEVQKAQLEGRLEEKESLVKLQQEEL 878
KEE ++ +R E S + ++L K + S +L+ + EK+ +K +E L
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELL 817
Score = 55.5 bits (132), Expect = 2e-07
Identities = 76/335 (22%), Positives = 145/335 (43%), Gaps = 58/335 (17%)
Query: 600 LIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL-- 657
L E+L + KD+ +I D + L SKE L+D+ L A+ +L
Sbjct: 601 LAEELHKVIAEKDK----QIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQA 656
Query: 658 ------IAQHRCQRTQA-----ETEARTLASMLR-EVERKNEELSVLL---KAQQVESER 702
A H ++ Q + + R L L+ E+ K EE +L KA + E ++
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQK 716
Query: 703 AQSDIEHLFQHNR----KLESVAEEHEILTKSYMELLQRN----ESTEKKNKDLQITCDS 754
Q+ + Q N+ ++E +E + K+ ELL+ + E++ ++ S
Sbjct: 717 LQTLVSE--QPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSS 774
Query: 755 LNKQIETVK-KLNESL---------------KEQNEKSIAQLIEKE-----EQRKEVQNQ 793
L K+++ +K K N+ + K+ KS+ +L+E E + K VQ
Sbjct: 775 LTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLS 834
Query: 794 LVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSL 853
+ + +L NL K +EE++ T++ E+KE+ + K L ++ + L +
Sbjct: 835 ITSKVQELQNL---LKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEV 891
Query: 854 ---EVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
+++A + EE E ++K ++ EL + M+
Sbjct: 892 AQHNLKEASSASQFEELEIVLKEKENELKRLEAML 926
Score = 48.1 bits (113), Expect = 4e-05
Identities = 59/284 (20%), Positives = 134/284 (47%), Gaps = 24/284 (8%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRL 657
++++E+++ + KD+ ++ + ++ E L +A+KE L + + + L
Sbjct: 727 KDVVEQMEKCIQEKDE----KLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782
Query: 658 IAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKL 717
A+ Q + A L ++ E + K + + LL+A+ ++ + ++ +
Sbjct: 783 KAKQNDQVSFASL-VEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQ------LSI 835
Query: 718 ESVAEEHEILTKSYMELLQRNEST-EKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKS 776
S +E + L K E + ++ E+K KDL T K ++ +++ NESLK + +
Sbjct: 836 TSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANT----GKWLQDLQEENESLK-AHVQE 890
Query: 777 IAQLIEKE----EQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDIL 832
+AQ KE Q +E++ L ++E++L L K +E + + + +D ++ +
Sbjct: 891 VAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLF 950
Query: 833 RKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQE 876
+ S+ EQ++++ +ASS + L+ E ++ + L E
Sbjct: 951 K---SQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNE 991
Score = 40.0 bits (92), Expect = 0.010
Identities = 51/218 (23%), Positives = 95/218 (43%), Gaps = 43/218 (19%)
Query: 668 AETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
+E EA + +L+E + V+ A + S+ + + H Q KL + +E
Sbjct: 297 SEDEALCVVDLLKE------KSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAA 350
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
TK + L + TEK+ ++ IT + +I T++K E ++ Q
Sbjct: 351 TKDRCKQLTQEMMTEKERSNVVIT--RMKDRIGTLEK---------EHNVFQ-------- 391
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDK----EETIDILRKELSR-TEQI 842
+K+ +Q+T+ + K + ++++ E + ++ ILR +S T Q+
Sbjct: 392 -----------NKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQL 440
Query: 843 RKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
+ S + + L A+L L EK KLQQEE+ K
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTG--KLQQEEVQK 476
Score = 38.5 bits (88), Expect = 0.029
Identities = 36/180 (20%), Positives = 81/180 (45%), Gaps = 24/180 (13%)
Query: 694 KAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL-------------TKSYMELLQRNES 740
KA++ + + S+ + +H KL+ E H +L T+ ++ LQR S
Sbjct: 1078 KAKECMAGTSGSEEVKVLEH--KLKEADEMHTLLQLECEKYKSVLAETEGILQKLQR--S 1133
Query: 741 TEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHK 800
E++ ++ D +K T+K++ S + +L + K+++N +REH
Sbjct: 1134 VEQEENKWKVKVDESHK---TIKQMQSSFTSSEQ----ELERLRSENKDIENLRREREHL 1186
Query: 801 LANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQL 860
L + + + +++ + ET+ LR E + +++ +L SLE+ ++++
Sbjct: 1187 EMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1246
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 65.5 bits (158), Expect = 2e-10
Identities = 63/279 (22%), Positives = 123/279 (44%), Gaps = 20/279 (7%)
Query: 616 DVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTL 675
D++I+D++ ++ ++++ + + A+ + Q R A + R T
Sbjct: 783 DLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQ--RNCAAYLKLRNWQWWRLFTK 840
Query: 676 ASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL-------T 728
L +V R+ EE+ Q ER Q L + +K + EE +L T
Sbjct: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
Query: 729 KSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQ-- 786
+ Y E + K ++L+ + ++E + + L+ + +K Q+++ EEQ
Sbjct: 901 ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
Query: 787 -----RKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQ 841
R+++Q + V E K+ L + V +++ L KER+ EE I L L+ E+
Sbjct: 961 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
Query: 842 IRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
K L+ + E ++LE RL+++E ++EL K
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEK----SRQELEK 1055
Score = 61.6 bits (148), Expect = 3e-09
Identities = 67/280 (23%), Positives = 117/280 (41%), Gaps = 44/280 (15%)
Query: 645 ETKALALAQA--DRLIAQHRCQRTQA--ETEARTLASMLREVERKNEELSVLLKAQQVES 700
ETKAL+LA+A + L A+ +RT + E L S +V + EL +A + +
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Query: 701 ERAQSDIEHLFQHNRKLESVAEEHEILTKSYM-----ELLQRNESTEKKNKDLQITCDSL 755
E ++ +E L + E E+ ++ +L R+E E+K + LQ
Sbjct: 1542 EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY 1601
Query: 756 NKQIE-----------TVKKLNESLKEQN----------EKSIAQLIEKEEQRKEVQNQL 794
++E KKL LK+ E++I QL + + Q K+ Q +L
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1661
Query: 795 VDREHKLANLHQKTKVQEEKIKTLQKEREDKEETI--------------DILRKELSRTE 840
D + K E+K K+L+ + +E + + L +EL+ +
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1721
Query: 841 QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
R L + LE + AQLE LEE++ ++ + + K
Sbjct: 1722 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
Score = 60.1 bits (144), Expect = 9e-09
Identities = 73/345 (21%), Positives = 156/345 (45%), Gaps = 34/345 (9%)
Query: 558 QQETEHIPRKMPWQSSN-HSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICD 616
+QE E + RK+ +S+ H ++ LK + + + E+LQ+ + D
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIADLQAQIAELK-----MQLAKKEEELQAALARLDDEIA 1104
Query: 617 VRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADR----LIAQHRCQRTQAETEA 672
+ + + + E++ S LQ+ L+++ A +A++ L + +T+ E
Sbjct: 1105 QKNNALKKIRELE-----GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1159
Query: 673 RTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQ-HNRKLESVAEEHEILTKSY 731
+ A+ ++ +E++VL KA E+ ++ ++ + Q H + +E + E+ E ++
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219
Query: 732 MELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQ 791
L + ++ EK+N DL L + + V E K++ E + +L K + +
Sbjct: 1220 ANLDKNKQTLEKENADLAGELRVLGQAKQEV----EHKKKKLEAQVQELQSKCSDGERAR 1275
Query: 792 NQLVDREHKLANLHQKTKVQEEKIKTLQKEREDK----EETIDILRKELSRTEQIRKELS 847
+L D+ HKL N + E + + E E K + + L +L T+++ +E +
Sbjct: 1276 AELNDKVHKLQN-------EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEET 1328
Query: 848 IKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLS 892
+ ++ + QLE EE+ SL EE+ ++ I +L+
Sbjct: 1329 RQKLNVSTKLRQLE---EERNSLQDQLDEEMEAKQNLERHISTLN 1370
Score = 59.3 bits (142), Expect = 2e-08
Identities = 61/267 (22%), Positives = 121/267 (45%), Gaps = 27/267 (10%)
Query: 627 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKN 686
E K S L +++ LQ+ L+ + A+A+ + R + + + L +L E+E +
Sbjct: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEM-------RVRLAAKKQELEEILHEMEARL 931
Query: 687 EELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 746
EE + QQ+++ER + + Q LE EE E + E+ KK +
Sbjct: 932 EEEED--RGQQLQAERKK-----MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
Query: 747 DLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQ 806
D + D N ++ +KL L+E+ L E+EE+ K + KL N H+
Sbjct: 985 DEILVMDDQNNKLSKERKL---LEERISDLTTNLAEEEEKAKNLT--------KLKNKHE 1033
Query: 807 KTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEE 866
+ + E +++ L+KE + ++E + RK ++++ + + K QL + EE
Sbjct: 1034 -SMISELEVR-LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE 1091
Query: 867 KESLVKLQQEELNKHSHMIAMIHSLSG 893
++ + +E+ + ++ + I L G
Sbjct: 1092 LQAALARLDDEIAQKNNALKKIRELEG 1118
Score = 58.2 bits (139), Expect = 3e-08
Identities = 78/300 (26%), Positives = 124/300 (41%), Gaps = 41/300 (13%)
Query: 623 MDVYEMKLSTLASKESRLQDLL-ETKALALAQADRLIAQHRCQRTQAETEARTLASMLRE 681
+D +S L K+ + LL E K ++ AD + + + ET+A +LA L E
Sbjct: 1436 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER-DRAEAEAREKETKALSLARALEE 1494
Query: 682 VERKNEEL---SVLLKAQQVESERAQSD----IEHLFQHNRKLESVAEEHEILTKSYMEL 734
EEL + +LKA+ + ++ D + L + R LE+ EE + EL
Sbjct: 1495 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE---MKTQLEEL 1551
Query: 735 LQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQL 794
++TE L++ +L Q E + + EQNE+ QL + Q E + +L
Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFERDLQARD---EQNEEKRRQL---QRQLHEYETEL 1605
Query: 795 VDREHKLANLHQKTKVQEEKIKTLQKERED----KEETIDILRKELSRTEQIRKEL---- 846
D + A K E +K L+ + + +EE I LRK ++ + ++EL
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
Query: 847 -------------SIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSG 893
KA SLE QL+ L E K Q +L K + SLSG
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEKEELAEELASSLSG 1723
Score = 56.2 bits (134), Expect = 1e-07
Identities = 55/247 (22%), Positives = 114/247 (46%), Gaps = 9/247 (3%)
Query: 633 LASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVL 692
+ +KE LQ E + A + L +H Q T+ + + E+ + EE+ V
Sbjct: 854 MQAKEDELQKTKERQQKAENELKELEQKHS-QLTEEKNLLQEQLQAETELYAEAEEMRVR 912
Query: 693 LKAQQVESERAQSDIE-HLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQIT 751
L A++ E E ++E L + + + + E + + + ++L ++ E E + LQ+
Sbjct: 913 LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE 972
Query: 752 CDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQ 811
+ +I+ ++ + +QN K + EE+ ++ L + E K NL +
Sbjct: 973 KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKH 1032
Query: 812 EEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLV 871
E I L+ + +E++ R+EL E+++++L AS Q A L+ ++ E + +
Sbjct: 1033 ESMISELEVRLKKEEKS----RQEL---EKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085
Query: 872 KLQQEEL 878
++EEL
Sbjct: 1086 AKKEEEL 1092
Score = 54.7 bits (130), Expect = 4e-07
Identities = 73/333 (21%), Positives = 139/333 (41%), Gaps = 36/333 (10%)
Query: 558 QQETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPG-LNIEELIEKLQSGMVVKDQICD 616
+QE EH +K+ Q ++ L DG + + + KLQ+ +
Sbjct: 1247 KQEVEHKKKKLEAQ---------VQELQSKCSDGERARAELNDKVHKLQNEVE------- 1290
Query: 617 VRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLA 676
++ +++ E K LA + L L+ L + R + Q E E +L
Sbjct: 1291 -SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1349
Query: 677 SMLRE-------VERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTK 729
L E +ER L++ L + + + S +E L + ++ + +E E LT+
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ---KEIENLTQ 1406
Query: 730 SYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKE 789
Y E + EK LQ D L ++ ++L +L E+ ++ QL+ +E K
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL-EKKQRKFDQLLAEE---KN 1462
Query: 790 VQNQLVD-REHKLANLHQKTKVQEEKIKTLQKEREDKEE---TIDILRKELSRTEQIRKE 845
+ ++ D R+ A +K + L++ E KEE T +L+ E+ + +
Sbjct: 1463 ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDD 1522
Query: 846 LSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 878
+ LE K LE ++EE ++ ++ ++EL
Sbjct: 1523 VGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Score = 50.8 bits (120), Expect = 6e-06
Identities = 57/269 (21%), Positives = 125/269 (46%), Gaps = 29/269 (10%)
Query: 637 ESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQ 696
E+ L+D + +ALA A +L + QA++ + ++++ + L +K
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK----LQAQMKDF 1657
Query: 697 QVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLN 756
Q E E A++ + +F ++ E A+ L M+L + + E+ K + + L
Sbjct: 1658 QRELEDARASRDEIFATAKENEKKAKS---LEADLMQLQEDLAAAERARKQADLEKEELA 1714
Query: 757 KQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLV---DREHK-------LAN--L 804
+++ + +L+++ + A++ + EE+ +E Q + DR K L+N
Sbjct: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1774
Query: 805 HQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE-QIRKELSIKASSLEVQKAQLEGR 863
+++ Q+ + Q ER++KE LR +L E ++ + ++LE + AQLE +
Sbjct: 1775 TERSTAQKNESARQQLERQNKE-----LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1829
Query: 864 LE----EKESLVKLQQEELNKHSHMIAMI 888
+E EK++ K +++ K ++ +
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKEILLQV 1858
Score = 50.8 bits (120), Expect = 6e-06
Identities = 54/252 (21%), Positives = 116/252 (46%), Gaps = 20/252 (7%)
Query: 635 SKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLK 694
S E+ L L E LA A+R Q ++ + E + S ++ + L +
Sbjct: 1684 SLEADLMQLQED----LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1739
Query: 695 AQQVESERAQSDIEHLFQHNRKLESVAEE--HEILTKSYMELLQRNESTEKKNKDLQITC 752
+ E E Q ++E + RK AE+ +E+ T+ ST +KN+ +
Sbjct: 1740 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE---------RSTAQKNESARQQL 1790
Query: 753 DSLNKQIET-VKKLNESLKEQNEKSIAQLIEKEEQRKE-VQNQLVDREHKLANLHQKTKV 810
+ NK++ + + ++ ++K + + +IA L K Q +E V+ + +++ +L QK K
Sbjct: 1791 ERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKK 1850
Query: 811 QEEKIKTLQKEREDKEETIDILRKELSRTEQIRKEL---SIKASSLEVQKAQLEGRLEEK 867
+E + ++ ER+ E+ + K +R +Q++++L ++ + + +L+ L+E
Sbjct: 1851 LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEA 1910
Query: 868 ESLVKLQQEELN 879
+ E+N
Sbjct: 1911 TESNEAMGREVN 1922
Score = 48.1 bits (113), Expect = 4e-05
Identities = 49/231 (21%), Positives = 104/231 (45%), Gaps = 29/231 (12%)
Query: 624 DVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEAR---------- 673
D+ +++ A++ +R Q LE + LA A L ++ Q + EAR
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1747
Query: 674 ------TLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
++ +R+ ++ E+LS L ++ +++ +S + L + N++L S E E
Sbjct: 1748 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1807
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
KS + + + Q+ ++ KQ T +SLK++++K L++ E++R
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT-----KSLKQKDKKLKEILLQVEDER 1862
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSR 838
K + E K + +++K +E E++ + I+ R++L R
Sbjct: 1863 KMAEQYKEQAE--------KGNARVKQLKRQLEEAEEESQRINANRRKLQR 1905
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 65.5 bits (158), Expect = 2e-10
Identities = 63/279 (22%), Positives = 123/279 (44%), Gaps = 20/279 (7%)
Query: 616 DVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTL 675
D++I+D++ ++ ++++ + + A+ + Q R A + R T
Sbjct: 790 DLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQ--RNCAAYLKLRNWQWWRLFTK 847
Query: 676 ASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL-------T 728
L +V R+ EE+ Q ER Q L + +K + EE +L T
Sbjct: 848 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 907
Query: 729 KSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQ-- 786
+ Y E + K ++L+ + ++E + + L+ + +K Q+++ EEQ
Sbjct: 908 ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 967
Query: 787 -----RKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQ 841
R+++Q + V E K+ L + V +++ L KER+ EE I L L+ E+
Sbjct: 968 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1027
Query: 842 IRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
K L+ + E ++LE RL+++E ++EL K
Sbjct: 1028 KAKNLTKLKNKHESMISELEVRLKKEEK----SRQELEK 1062
Score = 61.6 bits (148), Expect = 3e-09
Identities = 67/280 (23%), Positives = 117/280 (41%), Gaps = 44/280 (15%)
Query: 645 ETKALALAQA--DRLIAQHRCQRTQA--ETEARTLASMLREVERKNEELSVLLKAQQVES 700
ETKAL+LA+A + L A+ +RT + E L S +V + EL +A + +
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Query: 701 ERAQSDIEHLFQHNRKLESVAEEHEILTKSYM-----ELLQRNESTEKKNKDLQITCDSL 755
E ++ +E L + E E+ ++ +L R+E E+K + LQ
Sbjct: 1549 EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY 1608
Query: 756 NKQIE-----------TVKKLNESLKEQN----------EKSIAQLIEKEEQRKEVQNQL 794
++E KKL LK+ E++I QL + + Q K+ Q +L
Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1668
Query: 795 VDREHKLANLHQKTKVQEEKIKTLQKEREDKEETI--------------DILRKELSRTE 840
D + K E+K K+L+ + +E + + L +EL+ +
Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1728
Query: 841 QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
R L + LE + AQLE LEE++ ++ + + K
Sbjct: 1729 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1768
Score = 60.1 bits (144), Expect = 9e-09
Identities = 73/345 (21%), Positives = 156/345 (45%), Gaps = 34/345 (9%)
Query: 558 QQETEHIPRKMPWQSSN-HSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICD 616
+QE E + RK+ +S+ H ++ LK + + + E+LQ+ + D
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIADLQAQIAELK-----MQLAKKEEELQAALARLDDEIA 1111
Query: 617 VRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADR----LIAQHRCQRTQAETEA 672
+ + + + E++ S LQ+ L+++ A +A++ L + +T+ E
Sbjct: 1112 QKNNALKKIRELE-----GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166
Query: 673 RTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQ-HNRKLESVAEEHEILTKSY 731
+ A+ ++ +E++VL KA E+ ++ ++ + Q H + +E + E+ E ++
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 732 MELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQ 791
L + ++ EK+N DL L + + V E K++ E + +L K + +
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEV----EHKKKKLEAQVQELQSKCSDGERAR 1282
Query: 792 NQLVDREHKLANLHQKTKVQEEKIKTLQKEREDK----EETIDILRKELSRTEQIRKELS 847
+L D+ HKL N + E + + E E K + + L +L T+++ +E +
Sbjct: 1283 AELNDKVHKLQN-------EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEET 1335
Query: 848 IKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLS 892
+ ++ + QLE EE+ SL EE+ ++ I +L+
Sbjct: 1336 RQKLNVSTKLRQLE---EERNSLQDQLDEEMEAKQNLERHISTLN 1377
Score = 59.3 bits (142), Expect = 2e-08
Identities = 61/267 (22%), Positives = 121/267 (45%), Gaps = 27/267 (10%)
Query: 627 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKN 686
E K S L +++ LQ+ L+ + A+A+ + R + + + L +L E+E +
Sbjct: 886 EQKHSQLTEEKNLLQEQLQAETELYAEAEEM-------RVRLAAKKQELEEILHEMEARL 938
Query: 687 EELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 746
EE + QQ+++ER + + Q LE EE E + E+ KK +
Sbjct: 939 EEEED--RGQQLQAERKK-----MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 991
Query: 747 DLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQ 806
D + D N ++ +KL L+E+ L E+EE+ K + KL N H+
Sbjct: 992 DEILVMDDQNNKLSKERKL---LEERISDLTTNLAEEEEKAKNLT--------KLKNKHE 1040
Query: 807 KTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEE 866
+ + E +++ L+KE + ++E + RK ++++ + + K QL + EE
Sbjct: 1041 -SMISELEVR-LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE 1098
Query: 867 KESLVKLQQEELNKHSHMIAMIHSLSG 893
++ + +E+ + ++ + I L G
Sbjct: 1099 LQAALARLDDEIAQKNNALKKIRELEG 1125
Score = 58.2 bits (139), Expect = 3e-08
Identities = 78/300 (26%), Positives = 124/300 (41%), Gaps = 41/300 (13%)
Query: 623 MDVYEMKLSTLASKESRLQDLL-ETKALALAQADRLIAQHRCQRTQAETEARTLASMLRE 681
+D +S L K+ + LL E K ++ AD + + + ET+A +LA L E
Sbjct: 1443 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER-DRAEAEAREKETKALSLARALEE 1501
Query: 682 VERKNEEL---SVLLKAQQVESERAQSD----IEHLFQHNRKLESVAEEHEILTKSYMEL 734
EEL + +LKA+ + ++ D + L + R LE+ EE + EL
Sbjct: 1502 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE---MKTQLEEL 1558
Query: 735 LQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQL 794
++TE L++ +L Q E + + EQNE+ QL + Q E + +L
Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFERDLQARD---EQNEEKRRQL---QRQLHEYETEL 1612
Query: 795 VDREHKLANLHQKTKVQEEKIKTLQKERED----KEETIDILRKELSRTEQIRKEL---- 846
D + A K E +K L+ + + +EE I LRK ++ + ++EL
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Query: 847 -------------SIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSG 893
KA SLE QL+ L E K Q +L K + SLSG
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEKEELAEELASSLSG 1730
Score = 56.2 bits (134), Expect = 1e-07
Identities = 55/247 (22%), Positives = 114/247 (46%), Gaps = 9/247 (3%)
Query: 633 LASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVL 692
+ +KE LQ E + A + L +H Q T+ + + E+ + EE+ V
Sbjct: 861 MQAKEDELQKTKERQQKAENELKELEQKHS-QLTEEKNLLQEQLQAETELYAEAEEMRVR 919
Query: 693 LKAQQVESERAQSDIE-HLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQIT 751
L A++ E E ++E L + + + + E + + + ++L ++ E E + LQ+
Sbjct: 920 LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE 979
Query: 752 CDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQ 811
+ +I+ ++ + +QN K + EE+ ++ L + E K NL +
Sbjct: 980 KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKH 1039
Query: 812 EEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLV 871
E I L+ + +E++ R+EL E+++++L AS Q A L+ ++ E + +
Sbjct: 1040 ESMISELEVRLKKEEKS----RQEL---EKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1092
Query: 872 KLQQEEL 878
++EEL
Sbjct: 1093 AKKEEEL 1099
Score = 54.7 bits (130), Expect = 4e-07
Identities = 73/333 (21%), Positives = 139/333 (41%), Gaps = 36/333 (10%)
Query: 558 QQETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPG-LNIEELIEKLQSGMVVKDQICD 616
+QE EH +K+ Q ++ L DG + + + KLQ+ +
Sbjct: 1254 KQEVEHKKKKLEAQ---------VQELQSKCSDGERARAELNDKVHKLQNEVE------- 1297
Query: 617 VRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLA 676
++ +++ E K LA + L L+ L + R + Q E E +L
Sbjct: 1298 -SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1356
Query: 677 SMLRE-------VERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTK 729
L E +ER L++ L + + + S +E L + ++ + +E E LT+
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ---KEIENLTQ 1413
Query: 730 SYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKE 789
Y E + EK LQ D L ++ ++L +L E+ ++ QL+ +E K
Sbjct: 1414 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL-EKKQRKFDQLLAEE---KN 1469
Query: 790 VQNQLVD-REHKLANLHQKTKVQEEKIKTLQKEREDKEE---TIDILRKELSRTEQIRKE 845
+ ++ D R+ A +K + L++ E KEE T +L+ E+ + +
Sbjct: 1470 ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDD 1529
Query: 846 LSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 878
+ LE K LE ++EE ++ ++ ++EL
Sbjct: 1530 VGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1562
Score = 50.8 bits (120), Expect = 6e-06
Identities = 57/269 (21%), Positives = 125/269 (46%), Gaps = 29/269 (10%)
Query: 637 ESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQ 696
E+ L+D + +ALA A +L + QA++ + ++++ + L +K
Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK----LQAQMKDF 1664
Query: 697 QVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLN 756
Q E E A++ + +F ++ E A+ L M+L + + E+ K + + L
Sbjct: 1665 QRELEDARASRDEIFATAKENEKKAKS---LEADLMQLQEDLAAAERARKQADLEKEELA 1721
Query: 757 KQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLV---DREHK-------LAN--L 804
+++ + +L+++ + A++ + EE+ +E Q + DR K L+N
Sbjct: 1722 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1781
Query: 805 HQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE-QIRKELSIKASSLEVQKAQLEGR 863
+++ Q+ + Q ER++KE LR +L E ++ + ++LE + AQLE +
Sbjct: 1782 TERSTAQKNESARQQLERQNKE-----LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1836
Query: 864 LE----EKESLVKLQQEELNKHSHMIAMI 888
+E EK++ K +++ K ++ +
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKEILLQV 1865
Score = 50.8 bits (120), Expect = 6e-06
Identities = 54/252 (21%), Positives = 116/252 (46%), Gaps = 20/252 (7%)
Query: 635 SKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLK 694
S E+ L L E LA A+R Q ++ + E + S ++ + L +
Sbjct: 1691 SLEADLMQLQED----LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1746
Query: 695 AQQVESERAQSDIEHLFQHNRKLESVAEE--HEILTKSYMELLQRNESTEKKNKDLQITC 752
+ E E Q ++E + RK AE+ +E+ T+ ST +KN+ +
Sbjct: 1747 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE---------RSTAQKNESARQQL 1797
Query: 753 DSLNKQIET-VKKLNESLKEQNEKSIAQLIEKEEQRKE-VQNQLVDREHKLANLHQKTKV 810
+ NK++ + + ++ ++K + + +IA L K Q +E V+ + +++ +L QK K
Sbjct: 1798 ERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKK 1857
Query: 811 QEEKIKTLQKEREDKEETIDILRKELSRTEQIRKEL---SIKASSLEVQKAQLEGRLEEK 867
+E + ++ ER+ E+ + K +R +Q++++L ++ + + +L+ L+E
Sbjct: 1858 LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEA 1917
Query: 868 ESLVKLQQEELN 879
+ E+N
Sbjct: 1918 TESNEAMGREVN 1929
Score = 48.1 bits (113), Expect = 4e-05
Identities = 49/231 (21%), Positives = 104/231 (45%), Gaps = 29/231 (12%)
Query: 624 DVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEAR---------- 673
D+ +++ A++ +R Q LE + LA A L ++ Q + EAR
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1754
Query: 674 ------TLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
++ +R+ ++ E+LS L ++ +++ +S + L + N++L S E E
Sbjct: 1755 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1814
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
KS + + + Q+ ++ KQ T +SLK++++K L++ E++R
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT-----KSLKQKDKKLKEILLQVEDER 1869
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSR 838
K + E K + +++K +E E++ + I+ R++L R
Sbjct: 1870 KMAEQYKEQAE--------KGNARVKQLKRQLEEAEEESQRINANRRKLQR 1912
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 65.5 bits (158), Expect = 2e-10
Identities = 63/279 (22%), Positives = 123/279 (44%), Gaps = 20/279 (7%)
Query: 616 DVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTL 675
D++I+D++ ++ ++++ + + A+ + Q R A + R T
Sbjct: 790 DLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQ--RNCAAYLKLRNWQWWRLFTK 847
Query: 676 ASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL-------T 728
L +V R+ EE+ Q ER Q L + +K + EE +L T
Sbjct: 848 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 907
Query: 729 KSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQ-- 786
+ Y E + K ++L+ + ++E + + L+ + +K Q+++ EEQ
Sbjct: 908 ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 967
Query: 787 -----RKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQ 841
R+++Q + V E K+ L + V +++ L KER+ EE I L L+ E+
Sbjct: 968 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1027
Query: 842 IRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
K L+ + E ++LE RL+++E ++EL K
Sbjct: 1028 KAKNLTKLKNKHESMISELEVRLKKEEK----SRQELEK 1062
Score = 61.6 bits (148), Expect = 3e-09
Identities = 67/280 (23%), Positives = 117/280 (41%), Gaps = 44/280 (15%)
Query: 645 ETKALALAQA--DRLIAQHRCQRTQA--ETEARTLASMLREVERKNEELSVLLKAQQVES 700
ETKAL+LA+A + L A+ +RT + E L S +V + EL +A + +
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Query: 701 ERAQSDIEHLFQHNRKLESVAEEHEILTKSYM-----ELLQRNESTEKKNKDLQITCDSL 755
E ++ +E L + E E+ ++ +L R+E E+K + LQ
Sbjct: 1549 EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY 1608
Query: 756 NKQIE-----------TVKKLNESLKEQN----------EKSIAQLIEKEEQRKEVQNQL 794
++E KKL LK+ E++I QL + + Q K+ Q +L
Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1668
Query: 795 VDREHKLANLHQKTKVQEEKIKTLQKEREDKEETI--------------DILRKELSRTE 840
D + K E+K K+L+ + +E + + L +EL+ +
Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1728
Query: 841 QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
R L + LE + AQLE LEE++ ++ + + K
Sbjct: 1729 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1768
Score = 60.1 bits (144), Expect = 9e-09
Identities = 73/345 (21%), Positives = 156/345 (45%), Gaps = 34/345 (9%)
Query: 558 QQETEHIPRKMPWQSSN-HSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICD 616
+QE E + RK+ +S+ H ++ LK + + + E+LQ+ + D
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIADLQAQIAELK-----MQLAKKEEELQAALARLDDEIA 1111
Query: 617 VRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADR----LIAQHRCQRTQAETEA 672
+ + + + E++ S LQ+ L+++ A +A++ L + +T+ E
Sbjct: 1112 QKNNALKKIRELE-----GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166
Query: 673 RTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQ-HNRKLESVAEEHEILTKSY 731
+ A+ ++ +E++VL KA E+ ++ ++ + Q H + +E + E+ E ++
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 732 MELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQ 791
L + ++ EK+N DL L + + V E K++ E + +L K + +
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEV----EHKKKKLEAQVQELQSKCSDGERAR 1282
Query: 792 NQLVDREHKLANLHQKTKVQEEKIKTLQKEREDK----EETIDILRKELSRTEQIRKELS 847
+L D+ HKL N + E + + E E K + + L +L T+++ +E +
Sbjct: 1283 AELNDKVHKLQN-------EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEET 1335
Query: 848 IKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLS 892
+ ++ + QLE EE+ SL EE+ ++ I +L+
Sbjct: 1336 RQKLNVSTKLRQLE---EERNSLQDQLDEEMEAKQNLERHISTLN 1377
Score = 59.3 bits (142), Expect = 2e-08
Identities = 61/267 (22%), Positives = 121/267 (45%), Gaps = 27/267 (10%)
Query: 627 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKN 686
E K S L +++ LQ+ L+ + A+A+ + R + + + L +L E+E +
Sbjct: 886 EQKHSQLTEEKNLLQEQLQAETELYAEAEEM-------RVRLAAKKQELEEILHEMEARL 938
Query: 687 EELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 746
EE + QQ+++ER + + Q LE EE E + E+ KK +
Sbjct: 939 EEEED--RGQQLQAERKK-----MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 991
Query: 747 DLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQ 806
D + D N ++ +KL L+E+ L E+EE+ K + KL N H+
Sbjct: 992 DEILVMDDQNNKLSKERKL---LEERISDLTTNLAEEEEKAKNLT--------KLKNKHE 1040
Query: 807 KTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEE 866
+ + E +++ L+KE + ++E + RK ++++ + + K QL + EE
Sbjct: 1041 -SMISELEVR-LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE 1098
Query: 867 KESLVKLQQEELNKHSHMIAMIHSLSG 893
++ + +E+ + ++ + I L G
Sbjct: 1099 LQAALARLDDEIAQKNNALKKIRELEG 1125
Score = 58.2 bits (139), Expect = 3e-08
Identities = 78/300 (26%), Positives = 124/300 (41%), Gaps = 41/300 (13%)
Query: 623 MDVYEMKLSTLASKESRLQDLL-ETKALALAQADRLIAQHRCQRTQAETEARTLASMLRE 681
+D +S L K+ + LL E K ++ AD + + + ET+A +LA L E
Sbjct: 1443 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER-DRAEAEAREKETKALSLARALEE 1501
Query: 682 VERKNEEL---SVLLKAQQVESERAQSD----IEHLFQHNRKLESVAEEHEILTKSYMEL 734
EEL + +LKA+ + ++ D + L + R LE+ EE + EL
Sbjct: 1502 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE---MKTQLEEL 1558
Query: 735 LQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQL 794
++TE L++ +L Q E + + EQNE+ QL + Q E + +L
Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFERDLQARD---EQNEEKRRQL---QRQLHEYETEL 1612
Query: 795 VDREHKLANLHQKTKVQEEKIKTLQKERED----KEETIDILRKELSRTEQIRKEL---- 846
D + A K E +K L+ + + +EE I LRK ++ + ++EL
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Query: 847 -------------SIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSG 893
KA SLE QL+ L E K Q +L K + SLSG
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEKEELAEELASSLSG 1730
Score = 56.2 bits (134), Expect = 1e-07
Identities = 55/247 (22%), Positives = 114/247 (46%), Gaps = 9/247 (3%)
Query: 633 LASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVL 692
+ +KE LQ E + A + L +H Q T+ + + E+ + EE+ V
Sbjct: 861 MQAKEDELQKTKERQQKAENELKELEQKHS-QLTEEKNLLQEQLQAETELYAEAEEMRVR 919
Query: 693 LKAQQVESERAQSDIE-HLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQIT 751
L A++ E E ++E L + + + + E + + + ++L ++ E E + LQ+
Sbjct: 920 LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE 979
Query: 752 CDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQ 811
+ +I+ ++ + +QN K + EE+ ++ L + E K NL +
Sbjct: 980 KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKH 1039
Query: 812 EEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLV 871
E I L+ + +E++ R+EL E+++++L AS Q A L+ ++ E + +
Sbjct: 1040 ESMISELEVRLKKEEKS----RQEL---EKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1092
Query: 872 KLQQEEL 878
++EEL
Sbjct: 1093 AKKEEEL 1099
Score = 54.7 bits (130), Expect = 4e-07
Identities = 73/333 (21%), Positives = 139/333 (41%), Gaps = 36/333 (10%)
Query: 558 QQETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPG-LNIEELIEKLQSGMVVKDQICD 616
+QE EH +K+ Q ++ L DG + + + KLQ+ +
Sbjct: 1254 KQEVEHKKKKLEAQ---------VQELQSKCSDGERARAELNDKVHKLQNEVE------- 1297
Query: 617 VRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLA 676
++ +++ E K LA + L L+ L + R + Q E E +L
Sbjct: 1298 -SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1356
Query: 677 SMLRE-------VERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTK 729
L E +ER L++ L + + + S +E L + ++ + +E E LT+
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ---KEIENLTQ 1413
Query: 730 SYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKE 789
Y E + EK LQ D L ++ ++L +L E+ ++ QL+ +E K
Sbjct: 1414 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL-EKKQRKFDQLLAEE---KN 1469
Query: 790 VQNQLVD-REHKLANLHQKTKVQEEKIKTLQKEREDKEE---TIDILRKELSRTEQIRKE 845
+ ++ D R+ A +K + L++ E KEE T +L+ E+ + +
Sbjct: 1470 ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDD 1529
Query: 846 LSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 878
+ LE K LE ++EE ++ ++ ++EL
Sbjct: 1530 VGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1562
Score = 50.8 bits (120), Expect = 6e-06
Identities = 57/269 (21%), Positives = 125/269 (46%), Gaps = 29/269 (10%)
Query: 637 ESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQ 696
E+ L+D + +ALA A +L + QA++ + ++++ + L +K
Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK----LQAQMKDF 1664
Query: 697 QVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLN 756
Q E E A++ + +F ++ E A+ L M+L + + E+ K + + L
Sbjct: 1665 QRELEDARASRDEIFATAKENEKKAKS---LEADLMQLQEDLAAAERARKQADLEKEELA 1721
Query: 757 KQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLV---DREHK-------LAN--L 804
+++ + +L+++ + A++ + EE+ +E Q + DR K L+N
Sbjct: 1722 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1781
Query: 805 HQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE-QIRKELSIKASSLEVQKAQLEGR 863
+++ Q+ + Q ER++KE LR +L E ++ + ++LE + AQLE +
Sbjct: 1782 TERSTAQKNESARQQLERQNKE-----LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1836
Query: 864 LE----EKESLVKLQQEELNKHSHMIAMI 888
+E EK++ K +++ K ++ +
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKEILLQV 1865
Score = 50.8 bits (120), Expect = 6e-06
Identities = 54/252 (21%), Positives = 116/252 (46%), Gaps = 20/252 (7%)
Query: 635 SKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLK 694
S E+ L L E LA A+R Q ++ + E + S ++ + L +
Sbjct: 1691 SLEADLMQLQED----LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1746
Query: 695 AQQVESERAQSDIEHLFQHNRKLESVAEE--HEILTKSYMELLQRNESTEKKNKDLQITC 752
+ E E Q ++E + RK AE+ +E+ T+ ST +KN+ +
Sbjct: 1747 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE---------RSTAQKNESARQQL 1797
Query: 753 DSLNKQIET-VKKLNESLKEQNEKSIAQLIEKEEQRKE-VQNQLVDREHKLANLHQKTKV 810
+ NK++ + + ++ ++K + + +IA L K Q +E V+ + +++ +L QK K
Sbjct: 1798 ERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKK 1857
Query: 811 QEEKIKTLQKEREDKEETIDILRKELSRTEQIRKEL---SIKASSLEVQKAQLEGRLEEK 867
+E + ++ ER+ E+ + K +R +Q++++L ++ + + +L+ L+E
Sbjct: 1858 LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEA 1917
Query: 868 ESLVKLQQEELN 879
+ E+N
Sbjct: 1918 TESNEAMGREVN 1929
Score = 48.1 bits (113), Expect = 4e-05
Identities = 49/231 (21%), Positives = 104/231 (45%), Gaps = 29/231 (12%)
Query: 624 DVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEAR---------- 673
D+ +++ A++ +R Q LE + LA A L ++ Q + EAR
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1754
Query: 674 ------TLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
++ +R+ ++ E+LS L ++ +++ +S + L + N++L S E E
Sbjct: 1755 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1814
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
KS + + + Q+ ++ KQ T +SLK++++K L++ E++R
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT-----KSLKQKDKKLKEILLQVEDER 1869
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSR 838
K + E K + +++K +E E++ + I+ R++L R
Sbjct: 1870 KMAEQYKEQAE--------KGNARVKQLKRQLEEAEEESQRINANRRKLQR 1912
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 65.5 bits (158), Expect = 2e-10
Identities = 63/279 (22%), Positives = 123/279 (44%), Gaps = 20/279 (7%)
Query: 616 DVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTL 675
D++I+D++ ++ ++++ + + A+ + Q R A + R T
Sbjct: 783 DLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQ--RNCAAYLKLRNWQWWRLFTK 840
Query: 676 ASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL-------T 728
L +V R+ EE+ Q ER Q L + +K + EE +L T
Sbjct: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
Query: 729 KSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQ-- 786
+ Y E + K ++L+ + ++E + + L+ + +K Q+++ EEQ
Sbjct: 901 ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
Query: 787 -----RKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQ 841
R+++Q + V E K+ L + V +++ L KER+ EE I L L+ E+
Sbjct: 961 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
Query: 842 IRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
K L+ + E ++LE RL+++E ++EL K
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEK----SRQELEK 1055
Score = 61.6 bits (148), Expect = 3e-09
Identities = 67/280 (23%), Positives = 117/280 (41%), Gaps = 44/280 (15%)
Query: 645 ETKALALAQA--DRLIAQHRCQRTQA--ETEARTLASMLREVERKNEELSVLLKAQQVES 700
ETKAL+LA+A + L A+ +RT + E L S +V + EL +A + +
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Query: 701 ERAQSDIEHLFQHNRKLESVAEEHEILTKSYM-----ELLQRNESTEKKNKDLQITCDSL 755
E ++ +E L + E E+ ++ +L R+E E+K + LQ
Sbjct: 1542 EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY 1601
Query: 756 NKQIE-----------TVKKLNESLKEQN----------EKSIAQLIEKEEQRKEVQNQL 794
++E KKL LK+ E++I QL + + Q K+ Q +L
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1661
Query: 795 VDREHKLANLHQKTKVQEEKIKTLQKEREDKEETI--------------DILRKELSRTE 840
D + K E+K K+L+ + +E + + L +EL+ +
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1721
Query: 841 QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
R L + LE + AQLE LEE++ ++ + + K
Sbjct: 1722 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
Score = 60.1 bits (144), Expect = 9e-09
Identities = 73/345 (21%), Positives = 156/345 (45%), Gaps = 34/345 (9%)
Query: 558 QQETEHIPRKMPWQSSN-HSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICD 616
+QE E + RK+ +S+ H ++ LK + + + E+LQ+ + D
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIADLQAQIAELK-----MQLAKKEEELQAALARLDDEIA 1104
Query: 617 VRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADR----LIAQHRCQRTQAETEA 672
+ + + + E++ S LQ+ L+++ A +A++ L + +T+ E
Sbjct: 1105 QKNNALKKIRELE-----GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1159
Query: 673 RTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQ-HNRKLESVAEEHEILTKSY 731
+ A+ ++ +E++VL KA E+ ++ ++ + Q H + +E + E+ E ++
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219
Query: 732 MELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQ 791
L + ++ EK+N DL L + + V E K++ E + +L K + +
Sbjct: 1220 ANLDKNKQTLEKENADLAGELRVLGQAKQEV----EHKKKKLEAQVQELQSKCSDGERAR 1275
Query: 792 NQLVDREHKLANLHQKTKVQEEKIKTLQKEREDK----EETIDILRKELSRTEQIRKELS 847
+L D+ HKL N + E + + E E K + + L +L T+++ +E +
Sbjct: 1276 AELNDKVHKLQN-------EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEET 1328
Query: 848 IKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLS 892
+ ++ + QLE EE+ SL EE+ ++ I +L+
Sbjct: 1329 RQKLNVSTKLRQLE---EERNSLQDQLDEEMEAKQNLERHISTLN 1370
Score = 59.3 bits (142), Expect = 2e-08
Identities = 61/267 (22%), Positives = 121/267 (45%), Gaps = 27/267 (10%)
Query: 627 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKN 686
E K S L +++ LQ+ L+ + A+A+ + R + + + L +L E+E +
Sbjct: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEM-------RVRLAAKKQELEEILHEMEARL 931
Query: 687 EELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 746
EE + QQ+++ER + + Q LE EE E + E+ KK +
Sbjct: 932 EEEED--RGQQLQAERKK-----MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
Query: 747 DLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQ 806
D + D N ++ +KL L+E+ L E+EE+ K + KL N H+
Sbjct: 985 DEILVMDDQNNKLSKERKL---LEERISDLTTNLAEEEEKAKNLT--------KLKNKHE 1033
Query: 807 KTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEE 866
+ + E +++ L+KE + ++E + RK ++++ + + K QL + EE
Sbjct: 1034 -SMISELEVR-LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE 1091
Query: 867 KESLVKLQQEELNKHSHMIAMIHSLSG 893
++ + +E+ + ++ + I L G
Sbjct: 1092 LQAALARLDDEIAQKNNALKKIRELEG 1118
Score = 58.2 bits (139), Expect = 3e-08
Identities = 78/300 (26%), Positives = 124/300 (41%), Gaps = 41/300 (13%)
Query: 623 MDVYEMKLSTLASKESRLQDLL-ETKALALAQADRLIAQHRCQRTQAETEARTLASMLRE 681
+D +S L K+ + LL E K ++ AD + + + ET+A +LA L E
Sbjct: 1436 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER-DRAEAEAREKETKALSLARALEE 1494
Query: 682 VERKNEEL---SVLLKAQQVESERAQSD----IEHLFQHNRKLESVAEEHEILTKSYMEL 734
EEL + +LKA+ + ++ D + L + R LE+ EE + EL
Sbjct: 1495 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE---MKTQLEEL 1551
Query: 735 LQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQL 794
++TE L++ +L Q E + + EQNE+ QL + Q E + +L
Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFERDLQARD---EQNEEKRRQL---QRQLHEYETEL 1605
Query: 795 VDREHKLANLHQKTKVQEEKIKTLQKERED----KEETIDILRKELSRTEQIRKEL---- 846
D + A K E +K L+ + + +EE I LRK ++ + ++EL
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
Query: 847 -------------SIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSG 893
KA SLE QL+ L E K Q +L K + SLSG
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEKEELAEELASSLSG 1723
Score = 56.2 bits (134), Expect = 1e-07
Identities = 55/247 (22%), Positives = 114/247 (46%), Gaps = 9/247 (3%)
Query: 633 LASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVL 692
+ +KE LQ E + A + L +H Q T+ + + E+ + EE+ V
Sbjct: 854 MQAKEDELQKTKERQQKAENELKELEQKHS-QLTEEKNLLQEQLQAETELYAEAEEMRVR 912
Query: 693 LKAQQVESERAQSDIE-HLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQIT 751
L A++ E E ++E L + + + + E + + + ++L ++ E E + LQ+
Sbjct: 913 LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE 972
Query: 752 CDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQ 811
+ +I+ ++ + +QN K + EE+ ++ L + E K NL +
Sbjct: 973 KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKH 1032
Query: 812 EEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLV 871
E I L+ + +E++ R+EL E+++++L AS Q A L+ ++ E + +
Sbjct: 1033 ESMISELEVRLKKEEKS----RQEL---EKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085
Query: 872 KLQQEEL 878
++EEL
Sbjct: 1086 AKKEEEL 1092
Score = 54.7 bits (130), Expect = 4e-07
Identities = 73/333 (21%), Positives = 139/333 (41%), Gaps = 36/333 (10%)
Query: 558 QQETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPG-LNIEELIEKLQSGMVVKDQICD 616
+QE EH +K+ Q ++ L DG + + + KLQ+ +
Sbjct: 1247 KQEVEHKKKKLEAQ---------VQELQSKCSDGERARAELNDKVHKLQNEVE------- 1290
Query: 617 VRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLA 676
++ +++ E K LA + L L+ L + R + Q E E +L
Sbjct: 1291 -SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1349
Query: 677 SMLRE-------VERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTK 729
L E +ER L++ L + + + S +E L + ++ + +E E LT+
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ---KEIENLTQ 1406
Query: 730 SYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKE 789
Y E + EK LQ D L ++ ++L +L E+ ++ QL+ +E K
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL-EKKQRKFDQLLAEE---KN 1462
Query: 790 VQNQLVD-REHKLANLHQKTKVQEEKIKTLQKEREDKEE---TIDILRKELSRTEQIRKE 845
+ ++ D R+ A +K + L++ E KEE T +L+ E+ + +
Sbjct: 1463 ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDD 1522
Query: 846 LSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 878
+ LE K LE ++EE ++ ++ ++EL
Sbjct: 1523 VGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Score = 50.8 bits (120), Expect = 6e-06
Identities = 57/269 (21%), Positives = 125/269 (46%), Gaps = 29/269 (10%)
Query: 637 ESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQ 696
E+ L+D + +ALA A +L + QA++ + ++++ + L +K
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK----LQAQMKDF 1657
Query: 697 QVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLN 756
Q E E A++ + +F ++ E A+ L M+L + + E+ K + + L
Sbjct: 1658 QRELEDARASRDEIFATAKENEKKAKS---LEADLMQLQEDLAAAERARKQADLEKEELA 1714
Query: 757 KQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLV---DREHK-------LAN--L 804
+++ + +L+++ + A++ + EE+ +E Q + DR K L+N
Sbjct: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1774
Query: 805 HQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTE-QIRKELSIKASSLEVQKAQLEGR 863
+++ Q+ + Q ER++KE LR +L E ++ + ++LE + AQLE +
Sbjct: 1775 TERSTAQKNESARQQLERQNKE-----LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1829
Query: 864 LE----EKESLVKLQQEELNKHSHMIAMI 888
+E EK++ K +++ K ++ +
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKEILLQV 1858
Score = 50.8 bits (120), Expect = 6e-06
Identities = 54/252 (21%), Positives = 116/252 (46%), Gaps = 20/252 (7%)
Query: 635 SKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLK 694
S E+ L L E LA A+R Q ++ + E + S ++ + L +
Sbjct: 1684 SLEADLMQLQED----LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1739
Query: 695 AQQVESERAQSDIEHLFQHNRKLESVAEE--HEILTKSYMELLQRNESTEKKNKDLQITC 752
+ E E Q ++E + RK AE+ +E+ T+ ST +KN+ +
Sbjct: 1740 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE---------RSTAQKNESARQQL 1790
Query: 753 DSLNKQIET-VKKLNESLKEQNEKSIAQLIEKEEQRKE-VQNQLVDREHKLANLHQKTKV 810
+ NK++ + + ++ ++K + + +IA L K Q +E V+ + +++ +L QK K
Sbjct: 1791 ERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKK 1850
Query: 811 QEEKIKTLQKEREDKEETIDILRKELSRTEQIRKEL---SIKASSLEVQKAQLEGRLEEK 867
+E + ++ ER+ E+ + K +R +Q++++L ++ + + +L+ L+E
Sbjct: 1851 LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEA 1910
Query: 868 ESLVKLQQEELN 879
+ E+N
Sbjct: 1911 TESNEAMGREVN 1922
Score = 48.1 bits (113), Expect = 4e-05
Identities = 49/231 (21%), Positives = 104/231 (45%), Gaps = 29/231 (12%)
Query: 624 DVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEAR---------- 673
D+ +++ A++ +R Q LE + LA A L ++ Q + EAR
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1747
Query: 674 ------TLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEIL 727
++ +R+ ++ E+LS L ++ +++ +S + L + N++L S E E
Sbjct: 1748 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1807
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQR 787
KS + + + Q+ ++ KQ T +SLK++++K L++ E++R
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT-----KSLKQKDKKLKEILLQVEDER 1862
Query: 788 KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSR 838
K + E K + +++K +E E++ + I+ R++L R
Sbjct: 1863 KMAEQYKEQAE--------KGNARVKQLKRQLEEAEEESQRINANRRKLQR 1905
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 65.5 bits (158), Expect = 2e-10
Identities = 78/356 (21%), Positives = 157/356 (44%), Gaps = 60/356 (16%)
Query: 598 EELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLET-KALALAQADR 656
+EL + +KD+I +R + D ST+ +LQDL + K + Q
Sbjct: 290 DELTSLAEETRALKDEIDVLRATS--DKANKLESTVEIYRQKLQDLNDLRKQVKTLQETN 347
Query: 657 LIAQHRCQRTQAETE-ARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNR 715
++ H + E + A + L +R+ ++L V L + ES+RA + L +
Sbjct: 348 MMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSS---ESKRADT----LAFEMK 400
Query: 716 KLESVAEEHEILTKSYMELLQRNESTEKKNKDL---QITCDSLNKQIETVKKLNESL--- 769
+LE E+HE L K L+++ ++ ++ N++L Q+ D LN+ + K E+L
Sbjct: 401 RLE---EKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAE 457
Query: 770 -----------KEQNEKSIAQLIEK---EEQRKEVQNQLVDREHKLANLHQKTKVQEEKI 815
+ Q+E + +L ++ E+ +E+Q QL + K+ L + ++ +E+I
Sbjct: 458 IMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERI 517
Query: 816 KTLQKEREDKEETIDI----------------LRKELSRTEQIRKELSIKASSLE----- 854
+ LQ++ ED ++++ L + + ++ +EL K +E
Sbjct: 518 RELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPD 577
Query: 855 ----VQKA-QLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSGGKINPETVNLSI 905
VQK +LE L++K+ +K +E + + K+NP + + +
Sbjct: 578 INQNVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIML 633
Score = 56.2 bits (134), Expect = 1e-07
Identities = 70/311 (22%), Positives = 132/311 (42%), Gaps = 42/311 (13%)
Query: 595 LNIEELIEKLQSGMV----VKDQICDVRISDIMDVYEMKLSTLASKESRLQD----LLET 646
+++EE ++K + K Q+ D+ + + + TLA + RL++ LL+
Sbjct: 355 VSLEEELKKANAARTQLETYKRQVQDLHVK--LSSESKRADTLAFEMKRLEEKHEALLKE 412
Query: 647 KALALAQADRLIAQH---RCQRTQAETEARTLASMLREVERKNEEL-------------- 689
K + Q D L + RC + Q + +T AS + E E+
Sbjct: 413 KERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQH 472
Query: 690 -SVLLKAQQV--ESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 746
+ +L+ QQ E+ER + E L Q +RK+ + E + + EL Q+ E +K +
Sbjct: 473 ENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQ 532
Query: 747 DLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQ 806
+ + E+ KL + L+ EK L E E+ ++ Q + D + +++Q
Sbjct: 533 E-----QGSKSEGESSSKLKQKLEAHMEK----LTEVHEELQKKQELIEDLQ---PDINQ 580
Query: 807 KTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEE 866
+ E LQK+ ED + + + L + + K L K + + L +L E
Sbjct: 581 NVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAE 640
Query: 867 KESLVKLQQEE 877
KE +++ + E
Sbjct: 641 KERRIEILESE 651
Score = 51.2 bits (121), Expect = 4e-06
Identities = 102/473 (21%), Positives = 192/473 (40%), Gaps = 83/473 (17%)
Query: 429 DDTLKMHIAKILTTVKCTTLIEQQFTYGKIDLGFGTKVADSELCKLAADVILKTLDLINK 488
++ ++ AK V C L +Q + + + ++ K DV+ T D NK
Sbjct: 259 EENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANK 318
Query: 489 LKPLVPGMEVSFYKILQDPRLITPLAFALTSDNREQVQSGLRILLEAAPLPDFPALVLGE 548
L+ V + + LQD +D R+QV++ L E + + L E
Sbjct: 319 LESTVE----IYRQKLQD-----------LNDLRKQVKT----LQETNMMYMHNTVSLEE 359
Query: 549 SIAANNAYRQQ------ETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGL------- 595
+ NA R Q + + + K+ SS ++ L++ L
Sbjct: 360 ELKKANAARTQLETYKRQVQDLHVKL---SSESKRADTLAFEMKRLEEKHEALLKEKERL 416
Query: 596 -----NIEELIEKLQSGMVVKDQI--CDVRISDIMDVYEMKLSTLASKESRLQDLLETKA 648
++E E+L+ V +D + D + + ++ + +E ++ E K
Sbjct: 417 IEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKM 476
Query: 649 LALAQ-----------ADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQ 697
L L Q ++L +HR + + ETE R +RE++++ E+L L+ Q
Sbjct: 477 LRLQQEGSENERIEELQEQLEQKHR-KMNELETEQRLSKERIRELQQQIEDLQKSLQEQG 535
Query: 698 VESERAQSDIEHLFQHNRKLESVAEEH-EILTKSYMELLQRNESTEKKNKDLQITCDSLN 756
+SE S KL+ E H E LT+ + EL ++ E E DLQ +N
Sbjct: 536 SKSEGESSS---------KLKQKLEAHMEKLTEVHEELQKKQELIE----DLQ---PDIN 579
Query: 757 KQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIK 816
+ ++ + +L +L++++E + + + + L + + L K +I
Sbjct: 580 QNVQKINELEAALQKKDE-------DMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIM 632
Query: 817 TLQKEREDKEETIDILRKE--LSRTEQIRKELSIKA---SSLEVQKAQLEGRL 864
L+K+ +KE I+IL E +++ ++L + A SL QK +E RL
Sbjct: 633 LLRKQLAEKERRIEILESECKVAKFRDYEEKLIVSAWYNKSLAFQKLGMESRL 685
Score = 37.4 bits (85), Expect = 0.064
Identities = 38/215 (17%), Positives = 95/215 (44%), Gaps = 9/215 (4%)
Query: 683 ERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTE 742
E+K E + ++ ++ + I+ L + L + L+ +
Sbjct: 132 EKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRALEELQEAL 191
Query: 743 KKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLA 802
+ ++L+ C+ L+ Q+ T++ SL +NE + + +++ + + N +V +++ A
Sbjct: 192 AEKEELRQRCEELDMQVTTLQDEKNSLVSENE-MMNEKLDQLDGSFDDPNTVVAKKYFHA 250
Query: 803 NLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLE- 861
L Q ++QEE + L+ ++D + L K+L + EL+ A K +++
Sbjct: 251 QL-QLEQLQEENFR-LEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDV 308
Query: 862 -----GRLEEKESLVKLQQEELNKHSHMIAMIHSL 891
+ + ES V++ +++L + + + +L
Sbjct: 309 LRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTL 343
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 65.5 bits (158), Expect = 2e-10
Identities = 52/211 (24%), Positives = 108/211 (51%), Gaps = 8/211 (3%)
Query: 679 LREVERKNEELS-VLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQR 737
+ ++ + E LS V+L +E ER Q + + RKL EE + K+ +E +Q+
Sbjct: 576 MTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQ 635
Query: 738 NESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDR 797
T++K + +I + KQ E++K+ + ++ + + +A+ + EE+R Q + ++
Sbjct: 636 EVETQRK--ETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQE-IEL 692
Query: 798 EHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQK 857
+ K +VQEE + + +K E I ++ +Q++KE + + LE++K
Sbjct: 693 QKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQE----LDQLQKEKDEQYAKLELEK 748
Query: 858 AQLEGRLEEKESLVKLQQEELNKHSHMIAMI 888
+LE + +E+ LV +E+L + MI ++
Sbjct: 749 KRLEEQEKEQVMLVAHLEEQLREKQEMIQLL 779
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/226 (23%), Positives = 112/226 (49%), Gaps = 15/226 (6%)
Query: 660 QHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLES 719
Q R + + E++ + + M E ++K+++ + Q+VE++R +++I L Q ++ ES
Sbjct: 601 QQREELEKLESKRKLIEEM--EEKQKSDKAELERMQQEVETQRKETEIVQL-QIRKQEES 657
Query: 720 VAEEHEILTKSYMELLQRNESTEKKN--KDLQITCDSLNKQIETVKKLNESLKEQNEKSI 777
+ + +LL E E++ + +I ++ ET ++ E L+ E +
Sbjct: 658 LKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNN 717
Query: 778 AQLIEK-------EEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETID 830
+ EK ++ +KE Q E + L ++ K Q + L+++ +K+E I
Sbjct: 718 NEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQ 777
Query: 831 ILRK-ELSRTEQIRKEL-SIKASSLEVQKAQLEGRLEEKESLVKLQ 874
+LR+ E+ E+ +++L I+ S L V++A+ G E+ E L K Q
Sbjct: 778 LLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGD-EDGEELEKAQ 822
Score = 43.9 bits (102), Expect = 7e-04
Identities = 61/286 (21%), Positives = 125/286 (43%), Gaps = 49/286 (17%)
Query: 667 QAETEARTLASMLREVERKNEELSVLLKAQQVE-SERAQSDIEHLFQHNRKLESVA---- 721
+ E E L + L E R+ +E+ LL+ +V+ E + D+E + + +++
Sbjct: 753 EQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGD 812
Query: 722 EEHEILTKSYMELLQ--RNESTEKKN--KDLQITCDSLNKQIETVKKLNESLKEQNEKSI 777
E+ E L K+ + + R + + N KDL D L K+++ +++ E LK +++K
Sbjct: 813 EDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKE- 871
Query: 778 AQLIEKEEQR--------------KEVQNQLVDREHKLANL---HQKTKVQEEK------ 814
++L+EK ++ K V+ +L +E +L L H T ++E++
Sbjct: 872 SRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEIL 931
Query: 815 ----------IKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRL 864
+ ++KE E+KEE + + ++ ++++ A+ ++ +
Sbjct: 932 DRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEK 991
Query: 865 EEKESLVKLQQEELNK------HSHMIAMIHSLSGGKINPETVNLS 904
E ES K Q+E L + H HS G +I + L+
Sbjct: 992 EILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLA 1037
Score = 39.3 bits (90), Expect = 0.017
Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 39/272 (14%)
Query: 641 QDLLETKALALAQADRLIAQHR---CQRTQAETEARTLASMLREVERKNEELSVLLKAQ- 696
Q++LE + RL+ +H T+ + + + ++ K +L LL+
Sbjct: 858 QEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHL 917
Query: 697 QVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCD--- 753
E Q E L + L++ + E + E L + ++ + + LQ T +
Sbjct: 918 PTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTA 977
Query: 754 SLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDRE-----------HKLA 802
++ +Q E V+K + + E EK + +E+ R E ++ + R KLA
Sbjct: 978 NIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLA 1037
Query: 803 NLHQKTKVQ-------EEKIKTLQKEREDKEETIDILRKELSRTEQIRK------ELSIK 849
+L+ ++ Q E + + L+K++E E I L++++ + ++K E +
Sbjct: 1038 SLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVA 1097
Query: 850 ASSLEVQKAQLEGRLEEKESLVKLQQEELNKH 881
+SSL V EK LV L +N +
Sbjct: 1098 SSSLPVS--------AEKSHLVPLMDARINAY 1121
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 65.1 bits (157), Expect = 3e-10
Identities = 86/359 (23%), Positives = 158/359 (44%), Gaps = 52/359 (14%)
Query: 548 ESIAANNAYRQQETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSG 607
E + N Y E I + + N + I LT +++G L E ++KL
Sbjct: 1492 ELLKLKNTYE----ESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKL--- 1544
Query: 608 MVVKDQICDVRISDIMDVYEMKLSTLASKESRLQ-DLLETKA---LALAQADRLIAQHRC 663
++++ +V+++ ++ E L SK Q +LLE KA L++ D I R
Sbjct: 1545 --IEEEKTEVQVT--LEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRR 1600
Query: 664 QR--------TQAETEARTLASMLREVERKNEELSVL-----------------LKAQQV 698
++ + ++EA++ + R ++ E+L+ + L Q+
Sbjct: 1601 KQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQI 1660
Query: 699 ESERAQSDIEHLFQHNRKLE---SVAEEHEILTKSYMELLQR-NESTEKKNKDLQITCDS 754
+ + Q ++ Q N L+ +VAE L +S +E L+ E TE+ + +
Sbjct: 1661 QIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLE 1720
Query: 755 LNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKL-------ANLHQK 807
++I N SL Q +K A + +++ +EV + + E K ANL ++
Sbjct: 1721 ATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEE 1780
Query: 808 TKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIK-ASSLEVQKAQLEGRLE 865
K +++ I L++ RE+ E+TI L+K L+ EQ+ S K LE + +LEG LE
Sbjct: 1781 LKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELE 1839
Score = 63.5 bits (153), Expect = 8e-10
Identities = 66/292 (22%), Positives = 136/292 (46%), Gaps = 25/292 (8%)
Query: 596 NIEELIEKLQSGMVVKDQI-CDVRISDIMDVYEMKL---STLASKESRLQDLLETKALAL 651
N+EE E L +K +I + R+ ++ + E + S L ++ +L+D +
Sbjct: 912 NVEEQCEWL-----IKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEI 966
Query: 652 AQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLF 711
+ ++ + ++ E + + L EVE NE++S L +A +V E Q ++ L
Sbjct: 967 DDLETMLVKSEKEKRTTEHKVKNLTE---EVEFLNEDISKLNRAAKVVQEAHQQTLDDLH 1023
Query: 712 QHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLN-ESLK 770
KL S+++ + L + EL E ++ + ++ C+ ++E KLN ES++
Sbjct: 1024 MEEEKLSSLSKANLKLEQQVDEL----EGALEQERKARMNCERELHKLEGNLKLNRESME 1079
Query: 771 --EQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEET 828
E +++ +A+ + K+E N V+ E L QKT +K LQ + +D +E
Sbjct: 1080 NLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKT------VKELQTQIKDLKEK 1133
Query: 829 IDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
++ R ++ E+ R +L+ + L + ++ G + + K Q+ + K
Sbjct: 1134 LEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQK 1185
Score = 56.6 bits (135), Expect = 1e-07
Identities = 63/286 (22%), Positives = 126/286 (44%), Gaps = 35/286 (12%)
Query: 630 LSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEEL 689
+ L S + L + L K L L+Q + + + Q + + L + +++++ K E
Sbjct: 1078 MENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAE 1137
Query: 690 SVLLKAQQVESERAQSDI-EHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDL 748
+ + + ER ++D+ + L N +LE V S + L+ + E K + L
Sbjct: 1138 ----RTTRAKMERERADLTQDLADLNERLEEVGG-------SSLAQLEITKKQETKFQKL 1186
Query: 749 QITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQL--------VDREHK 800
+ ET + SLK+++ S+A+L + E ++V+ +L ++ +
Sbjct: 1187 HRDMEEATLHFETT---SASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDL 1243
Query: 801 LANLHQKT--KVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKA 858
L + Q T K EK+ TL +ER + +L + Q+ +L+ + + L +
Sbjct: 1244 LTRVEQMTRAKANAEKLCTLYEERLHEATA------KLDKVTQLANDLAAQKTKLWSESG 1297
Query: 859 QLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSGGKINPETVNLS 904
+ RLEEKE+L+ E + + I + G++ ET + S
Sbjct: 1298 EFLRRLEEKEALINQLSREKSNFTRQIEDLR----GQLEKETKSQS 1339
Score = 50.1 bits (118), Expect = 9e-06
Identities = 61/241 (25%), Positives = 112/241 (46%), Gaps = 36/241 (14%)
Query: 649 LALAQADRLIAQHRCQRTQAETEARTLAS--MLREVERKNEELSVLLKAQQVESERAQSD 706
L L D L + + A + + L S L + ++K+EE LL A Q E
Sbjct: 1433 LQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKE------- 1485
Query: 707 IEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQI-ETVKKL 765
+++++ E L +Y E + E+ ++NK+LQ +L Q+ E K L
Sbjct: 1486 ----------VQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNL 1535
Query: 766 NESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLAN-----LHQKTKVQEEKIKTLQK 820
E K + +LIE E++ EVQ L + E L LH + ++ E K + L++
Sbjct: 1536 TEMEK------VKKLIE--EEKTEVQVTLEETEGALERNESKILHFQLELLEAKAE-LER 1586
Query: 821 EREDKEETID-ILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELN 879
+ +K+E I+ RK+ + ++ L +A S ++ +L+ ++EE + ++LQ N
Sbjct: 1587 KLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKS-RIEVTRLKKKMEEDLNEMELQLSCAN 1645
Query: 880 K 880
+
Sbjct: 1646 R 1646
Score = 44.3 bits (103), Expect = 5e-04
Identities = 58/260 (22%), Positives = 107/260 (41%), Gaps = 54/260 (20%)
Query: 671 EARTLASMLREVERKNEELSVLLKAQQVESERAQSD-IEHLFQHNRKLESVAEEHEILTK 729
E L L + E + EEL KA+QV + ++D I L L +V E+ E L K
Sbjct: 867 ECAQLQKALEKSEFQREEL----KAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIK 922
Query: 730 SYM-------ELLQRNESTEKKNKDL-------QITCDSLNKQI---ETVKKLNESLKEQ 772
S + EL +R E E+ N +L + C L K+I ET+ +E K
Sbjct: 923 SKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRT 982
Query: 773 NEKSIAQLIEK------------------EEQRKEVQNQLVDREHKLANLHQKTKVQEEK 814
E + L E+ +E ++ + L E KL++L + E++
Sbjct: 983 TEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQ 1042
Query: 815 IKTL--------------QKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQL 860
+ L ++E E + + R+ + E ++ L+ + E++ +Q+
Sbjct: 1043 VDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQM 1102
Query: 861 EGRLEEKESLVKLQQEELNK 880
++E ++ LV Q+ + +
Sbjct: 1103 NSKVENEKGLVAQLQKTVKE 1122
Score = 40.8 bits (94), Expect = 0.006
Identities = 45/213 (21%), Positives = 95/213 (44%), Gaps = 13/213 (6%)
Query: 664 QRTQ-AETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAE 722
QRT+ E + LA L+E E + A+ ERA+ ++ + L + +
Sbjct: 1393 QRTEDLEDAKKELAIRLQEAA----EAMGVANARNASLERARHQLQ--LELGDALSDLGK 1446
Query: 723 EHEILTKSYMELLQRNEST---EKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQ 779
+ + LQ ++ ++K+++ Q D+ K+++ + LK E+SI
Sbjct: 1447 VRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVG 1506
Query: 780 LIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRT 839
+ K +Q ++ + +++ + E+ K +++E+ + + T++ L R
Sbjct: 1507 QETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERN 1566
Query: 840 EQIRKELSIKASSLEVQKAQLEGRLEEKESLVK 872
E K L + LE KA+LE +L EK+ ++
Sbjct: 1567 ES--KILHFQLELLEA-KAELERKLSEKDEEIE 1596
Score = 40.0 bits (92), Expect = 0.010
Identities = 27/131 (20%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Query: 755 LNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEK 814
L ++ ++K E + Q E+ A+ + +++ ++ QL + LAN+ EE+
Sbjct: 864 LKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANV-------EEQ 916
Query: 815 IKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQ 874
+ L K + E + L + + E+I EL+ + LE + +L+ +++ E+++
Sbjct: 917 CEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKS 976
Query: 875 QEELNKHSHMI 885
++E H +
Sbjct: 977 EKEKRTTEHKV 987
Score = 37.7 bits (86), Expect = 0.049
Identities = 39/166 (23%), Positives = 73/166 (43%), Gaps = 16/166 (9%)
Query: 698 VESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNK 757
V+S ++ L + +L+ E+ E + EL + S ++ DL + + +
Sbjct: 852 VKSSEVGEEVAGLKEECAQLQKALEKSEFQRE---ELKAKQVSLTQEKNDLILQLQAEQE 908
Query: 758 QIETVKKLNESL---KEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEK 814
+ V++ E L K Q E + +L E+ E+ +E+ ++L R KL E++
Sbjct: 909 TLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKL----------EDE 958
Query: 815 IKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQL 860
L+KE +D E + KE TE K L+ + L ++L
Sbjct: 959 CFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKL 1004
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 65.1 bits (157), Expect = 3e-10
Identities = 58/219 (26%), Positives = 112/219 (51%), Gaps = 22/219 (10%)
Query: 669 ETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLES-VAEEHEIL 727
E R + S+L E++ + +L L + Q + A ++E + +K S ++E+ E
Sbjct: 1791 EDRDRKVESLLNEMKELDSKLH-LQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYF 1849
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQI--ETVKKLNESLKEQNEKSIAQLIEKEE 785
+ + ELLQR E++E N DL++ D +++ + V K+N+S KE+ ++ E
Sbjct: 1850 SCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKER-------FLDVEN 1902
Query: 786 QRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKEL----SRTEQ 841
+ ++++ EH+ L +V + + L+K+ E+K++ I L +EL S Q
Sbjct: 1903 ELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQ 1962
Query: 842 IRKEL---SIKASSLEVQKAQLEGRLEEKESLVKLQQEE 877
+R EL S K ++L+ QL +++EK ++ Q E
Sbjct: 1963 LRGELDTMSKKTTALD----QLSEKMKEKTQELESHQSE 1997
Score = 63.5 bits (153), Expect = 8e-10
Identities = 78/333 (23%), Positives = 152/333 (45%), Gaps = 55/333 (16%)
Query: 588 LKDGVPGLNIEELIEKLQSGMVVKD--------QICDVRISDI---MDVYEMKLSTLASK 636
LKD V L E + + +V+ D + +I ++ + V+E+ L TL S+
Sbjct: 2152 LKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSE 2211
Query: 637 ESRLQDLLETKALALAQADRLIAQHRC---QRTQAE----TEARTLASMLR-EVERKNEE 688
+ L ++ K L++ D+L++ + ++ QAE E++T ML+ +++ NE
Sbjct: 2212 KENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEA 2271
Query: 689 LSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKN--- 745
++ L Q++ QS L+ EE L S +L R E+ EKK
Sbjct: 2272 VAALCGDQEIMKATEQS-----------LDPPIEEEHQLRNSIEKLRARLEADEKKQLCV 2320
Query: 746 ----KDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKL 801
K+ + D L ++E +++ E + E + +E E + EV+ + K+
Sbjct: 2321 LQQLKESEHHADLLKGRVENLERELEIARTNQEHA---ALEAENSKGEVET----LKAKI 2373
Query: 802 ANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLE---VQKA 858
+ Q + E + T++ E+E+ L EL + ++ EL I SS E +K
Sbjct: 2374 EGMTQSLRGLELDVVTIRSEKEN-------LTNELQKEQERISELEIINSSFENILQEKE 2426
Query: 859 QLEGRLEEKES-LVKLQQEELNKHSHMIAMIHS 890
Q + +++EK S +++ Q +L + + +A +H+
Sbjct: 2427 QEKVQMKEKSSTAMEMLQTQLKELNERVAALHN 2459
Score = 56.2 bits (134), Expect = 1e-07
Identities = 55/279 (19%), Positives = 125/279 (44%), Gaps = 28/279 (10%)
Query: 633 LASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEART-----------LASMLRE 681
+ KE Q+ L + + D+ Q + + TQ +A+ L S+ ++
Sbjct: 389 IKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQ 448
Query: 682 VERKNEELSVLL-------KAQQVESERAQSDIEHLFQHNRKLESVAEEH-------EIL 727
+E EE L +A Q++ + +E + + N L+S +E+ E
Sbjct: 449 LENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAE 508
Query: 728 TKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQN-EKSIAQLIEKEEQ 786
K+ + L ++++ ++ K + +++ + ++ +K+N+ EK + + E+Q
Sbjct: 509 LKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQ--EKINQQENSLTLEKLKLAVADLEKQ 566
Query: 787 RKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKEL 846
R Q+ L REH + L+ K E++ K L E K++ + L++E + + E
Sbjct: 567 RDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSEN 626
Query: 847 SIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMI 885
+ +E +K L+ ++ E+ +K QQ + ++++ +
Sbjct: 627 EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERV 665
Score = 56.2 bits (134), Expect = 1e-07
Identities = 78/361 (21%), Positives = 154/361 (42%), Gaps = 38/361 (10%)
Query: 558 QQETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGL-----NIEELIEKLQSGMVVKD 612
Q E EH W+ N ++ LT L+ + L ++++ +E LQS +
Sbjct: 2543 QVEGEH----QLWKEQN----LELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLE 2594
Query: 613 QICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAET-- 670
++ D M E K++ + +KE+ LQ + A A+ ++ + R E
Sbjct: 2595 NELELTKMDKMSFVE-KVNKMTAKETELQREMHEMAQKTAELQEELSGEK-NRLAGELQL 2652
Query: 671 ---EARTLASMLREVERKNEELSVLLKAQQVESERAQSDI-EHLFQHNRKLESVAEEHEI 726
E ++ L+E+ +N EL L + + + E + ++ +L ++H+
Sbjct: 2653 LLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQA 2712
Query: 727 LTKSYMELLQRNESTEKKNKDLQITCDSLNK-QIETVKKLNESLKEQNEKSIAQLIEKEE 785
L + + T ++ + C S K +I+ +K E L + K+ Q++E+ +
Sbjct: 2713 LLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNN-SLKATTQILEELK 2771
Query: 786 QRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKE 845
+ K +D + L ++ + + K+K L K + EE +IL+KELS+ + +++
Sbjct: 2772 KTK------MDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2825
Query: 846 ------LSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSGGKINPE 899
+ K L + +L+ LEEK K E L+K+ ++ L K E
Sbjct: 2826 QKTGTVMDTKVDELTTEIKELKETLEEK---TKEADEYLDKYCSLLISHEKLEKAKEMLE 2882
Query: 900 T 900
T
Sbjct: 2883 T 2883
Score = 55.1 bits (131), Expect = 3e-07
Identities = 69/240 (28%), Positives = 112/240 (46%), Gaps = 26/240 (10%)
Query: 647 KALALAQADRLIAQHRCQRTQAETEAR--TLASMLREVERKNEELSVLLKAQQVESERAQ 704
KA + Q+ R + Q +T A +A L +E K +EL +L +VE+E Q
Sbjct: 869 KAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLL--NDKVETE--Q 924
Query: 705 SDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNK-QIETVK 763
++I+ L + N LE +E ++LL S EKK I SLNK +IE +
Sbjct: 925 AEIQELKKSNHLLEDSLKE--------LQLLSETLSLEKKEMSSII---SLNKREIEELT 973
Query: 764 KLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKERE 823
+ N +LKE N + + ++ + N + +RE ++ L + K +EK+ LQ+ E
Sbjct: 974 QENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYK--QEKLILLQRCEE 1031
Query: 824 DKEETIDILRKELSRTEQIRK---ELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNK 880
D+ +K + E+ K L+ S E +K +LE + KE+ K QE L K
Sbjct: 1032 TGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELE---QLKEAFAKEHQEFLTK 1088
Score = 54.3 bits (129), Expect = 5e-07
Identities = 65/318 (20%), Positives = 133/318 (41%), Gaps = 58/318 (18%)
Query: 627 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKN 686
E L + +++ L+ E K + + ++ +R Q E T++ +++ +
Sbjct: 1922 EADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLS 1981
Query: 687 EELSVLLKAQQVESERAQSDIEHLFQ--------HNRKLESVAEEHEILTKSYMELLQRN 738
E++ K Q++ES QS+ H Q L++++ + L K L ++
Sbjct: 1982 EKMKE--KTQELESH--QSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKL 2037
Query: 739 ESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLV--- 795
+S EK ++ L +T L QI + K E L +++E A+L E + ++ V L
Sbjct: 2038 QSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAAL 2097
Query: 796 --------------DREHKLANLHQKTKVQ-----------EEKIKTLQKEREDKEETID 830
+ H+L +K +V+ EK+K ++E + ++ ++
Sbjct: 2098 VEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVE 2157
Query: 831 ILRKELSRTEQ------------------IRKELSIKASSLEVQKAQLEGRLEEKESLVK 872
L +EL +E+ ++ ++ A SL+V + L EKE+L K
Sbjct: 2158 NLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTK 2217
Query: 873 LQQEELNKHSHMIAMIHS 890
QE+ + S + ++ S
Sbjct: 2218 QIQEKQGQLSELDKLLSS 2235
Score = 54.3 bits (129), Expect = 5e-07
Identities = 72/310 (23%), Positives = 148/310 (47%), Gaps = 33/310 (10%)
Query: 601 IEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQ 660
+++L M K Q + S+ + ++ + + K LQ L + L D+ Q
Sbjct: 1977 LDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLK--DKTHLQ 2034
Query: 661 HRCQRTQAETEARTLAS--MLREVERKNEELSVLLK-AQQVESERAQSDIEHLFQHNRKL 717
+ Q + +++A +L + ++ + N+E +L+K ++ +++ ++SD E L
Sbjct: 2035 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALE 2094
Query: 718 ESVAEEHEI---LTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKL------NES 768
++ E+ E L+ + E+ Q EK ++I D KQ+ +KL N+S
Sbjct: 2095 AALVEKGEFALRLSSTQEEVHQLRRGIEKLR--VRIEADE-KKQLHIAEKLKERERENDS 2151
Query: 769 LKEQNEKSIAQLIEKEEQRKEVQNQLV--DREHKLANLHQ-KTKVQE--EKIKTLQKE-- 821
LK++ E +E+E Q E +LV D E+ A + KT+++E +K + +
Sbjct: 2152 LKDKVEN-----LERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLV 2206
Query: 822 --REDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRL-EEKESLVKLQQEEL 878
R +KE ++++ + ++ K LS S LE +K Q E ++ EE ++ V++ Q +L
Sbjct: 2207 TLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLE-EKEQAEIQIKEESKTAVEMLQNQL 2265
Query: 879 NKHSHMIAMI 888
+ + +A +
Sbjct: 2266 KELNEAVAAL 2275
Score = 51.6 bits (122), Expect = 3e-06
Identities = 52/230 (22%), Positives = 103/230 (44%), Gaps = 25/230 (10%)
Query: 662 RCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVA 721
R + A EA + ++ K E ++ L+ +++ +S+ E+L +K +
Sbjct: 2349 RTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERI 2408
Query: 722 EEHEILTKSYMELLQRNESTEKKNKD--------LQITCDSLNKQIETVKKLNESLK--E 771
E EI+ S+ +LQ E + + K+ LQ LN+++ + E+ K E
Sbjct: 2409 SELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKE 2468
Query: 772 QNEKSIAQLIEKEEQR-----KEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKE 826
QN S + +E E+ + E +N + + + L Q+ + ++K+ E K+
Sbjct: 2469 QNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKL-------EKKD 2521
Query: 827 ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQE 876
E I L+ ++ EQ+ +LS ++ K Q LE + V+L+Q+
Sbjct: 2522 EEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQ---NLELRNLTVELEQK 2568
Score = 51.6 bits (122), Expect = 3e-06
Identities = 63/296 (21%), Positives = 134/296 (45%), Gaps = 24/296 (8%)
Query: 600 LIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRL---QDLLETKALALAQADR 656
L EK Q + +K+ + S M++ + +L L + + L Q+ + K L+
Sbjct: 2422 LQEKEQEKVQMKE-----KSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVE 2476
Query: 657 LIAQHRCQRTQAETEART----LASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQ 712
+ + Q Q EA+ L S + + ++ E+ L+ + E R ++ I+ Q
Sbjct: 2477 CLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQ 2536
Query: 713 HNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQ 772
KL V EH++ + +EL E+K + LQ SL +E ++ ++L+ +
Sbjct: 2537 LVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENE 2596
Query: 773 NEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKT-KVQEEKIKTLQKEREDKEETIDI 831
E + + E+ ++ + + + ++ + QKT ++QEE L E+ + +
Sbjct: 2597 LELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEE----LSGEKNRLAGELQL 2652
Query: 832 LRKELSRTEQIRKELSIKASSLE-------VQKAQLEGRLEEKESLVKLQQEELNK 880
L +E+ ++ KEL+++ S L+ + + EG++ E+ + +L+ E K
Sbjct: 2653 LLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEK 2708
Score = 49.3 bits (116), Expect = 2e-05
Identities = 59/285 (20%), Positives = 127/285 (44%), Gaps = 43/285 (15%)
Query: 627 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKN 686
E K + E+ L+++ + L Q+ + + + T ET MLR+++ K
Sbjct: 496 EQKAREVCHLEAELKNIKQ----CLNQSQNFAEEMKAKNTSQET-------MLRDLQEKI 544
Query: 687 EELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 746
+ L ++++ A +D+E ++ L E H +L + TEK++K
Sbjct: 545 NQQENSLTLEKLKL--AVADLEKQRDCSQDLLKKREHH------IEQLNDKLSKTEKESK 596
Query: 747 DLQITCDSLNKQIETVKK---LNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLAN 803
L + K+ E +K+ L K +NEK + Q+ E +++ +Q+++ E L
Sbjct: 597 ALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQM---ESEKENLQSKINHLETCLKT 653
Query: 804 LHQKTKVQEEKIKTLQKERED------------KEETIDILRKELSRTE-QIRKELSIKA 850
K+ E+++TL+ +RE+ +++++ ++L+ E Q + E S +
Sbjct: 654 QQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQK 713
Query: 851 SSLEVQK-----AQLEGRLEEKESLVKLQQEELNKHSHMIAMIHS 890
E++ +QL G++E+ E ++L E+ +H+
Sbjct: 714 HQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHA 758
Score = 48.9 bits (115), Expect = 2e-05
Identities = 60/284 (21%), Positives = 126/284 (44%), Gaps = 26/284 (9%)
Query: 618 RISDIMDVYEMKLSTLASKESRLQDLLETKAL-ALAQAD---RLIAQHRCQRT-----QA 668
+ D+ + Y ++ E+ ++ L KA L QA R IA+H+ + Q
Sbjct: 163 KYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQE 222
Query: 669 ETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILT 728
+T + ++ R R++ S Q+V R+ I ++ ++ + H +
Sbjct: 223 KTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLL-- 280
Query: 729 KSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRK 788
+L +N+ K +L++ K+++ + L+ Q EK+ +LIEKE+
Sbjct: 281 ---DQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLN 337
Query: 789 EVQNQLVDREHKLANLHQKTKVQEEKIKTLQK----EREDKEETIDILRKELSRTE-QIR 843
+ +++LV + K E+K+K L + +R++ E L +++ E + +
Sbjct: 338 KCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQ 397
Query: 844 KELSIKASSLEV-------QKAQLEGRLEEKESLVKLQQEELNK 880
+ELS + S + KA+L L++ +++ + Q EL+K
Sbjct: 398 EELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDK 441
Score = 47.0 bits (110), Expect = 8e-05
Identities = 68/340 (20%), Positives = 140/340 (41%), Gaps = 49/340 (14%)
Query: 564 IPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICDVRISDIM 623
+ +K + H CL G +E+L KLQ + ++IM
Sbjct: 703 LQQKAEFSDQKHQKEIENMCLKTSQLTG----QVEDLEHKLQ-----------LLSNEIM 747
Query: 624 DVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVE 683
D A ES L+DLL++K +L E R+L + ++
Sbjct: 748 DKDRCYQDLHAEYES-LRDLLKSKDASLVTN--------------EDHQRSLLAFDQQPA 792
Query: 684 RKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEK 743
+ +++ + + SER++ +E + + IL L ES ++
Sbjct: 793 MHHSFANIIGEQGSMPSERSECRLE--------ADQSPKNSAILQNRVDSLEFSLESQKQ 844
Query: 744 KNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLAN 803
N DLQ C+ L ++ ++ E+L + + + + E ++ ++Q ++ +A
Sbjct: 845 MNSDLQKQCEEL---VQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAE 901
Query: 804 LHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGR 863
+ +E++++ L + E ++ I L+K E KEL + + +L ++K ++
Sbjct: 902 TLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSI 961
Query: 864 LEEKESLVKLQQEELNKHSHMIAMIHSLSGGKINPETVNL 903
+ SL K + EEL + + + I++ +N E +NL
Sbjct: 962 I----SLNKREIEELTQENGTLKEINA----SLNQEKMNL 993
Score = 38.9 bits (89), Expect = 0.022
Identities = 67/289 (23%), Positives = 115/289 (39%), Gaps = 45/289 (15%)
Query: 596 NIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLL-------ETKA 648
+I EL ++ + ++ Q C+ + D+ + K K S+L+ LL E +
Sbjct: 1010 SISELSDQYKQEKLILLQRCEETGNAYEDLSQ-KYKAAQEKNSKLECLLNECTSLCENRK 1068
Query: 649 LALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIE 708
L Q A+ E + + L E +N+ L + L+ Q +D
Sbjct: 1069 NELEQLKEAFAK----------EHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDN- 1117
Query: 709 HLFQHNRKLESVAEEHEILT---------KSYMELLQRNESTEKKNKDLQITCDSLNKQ- 758
Q+N K E+ + EI+T K +LLQ NE K K + C +L +
Sbjct: 1118 ---QNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMK-TKHECQNLESEP 1173
Query: 759 IETVKKLNESLKEQ-NEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKT 817
I K ES + Q N K L KE QLV E L N +E K++
Sbjct: 1174 IRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRN-------KELKLQE 1226
Query: 818 LQKEREDKEETIDILRKELSRTE----QIRKELSIKASSLEVQKAQLEG 862
+KE+E + + +R +L + Q ++ +K ++ ++ + G
Sbjct: 1227 SEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISG 1275
Score = 35.8 bits (81), Expect = 0.19
Identities = 23/106 (21%), Positives = 54/106 (50%), Gaps = 7/106 (6%)
Query: 775 KSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKE----REDKEETID 830
+++ ++ E E Q +++ + R+ +L +L + Q++K++ + E + + + ++
Sbjct: 15 RALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLME 74
Query: 831 ILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQE 876
I ++I EL +K S + Q+ QL K+ + KL+QE
Sbjct: 75 ICESLEKTKQKISHELQVKESQVNFQEGQLN---SGKKQIEKLEQE 117
Score = 30.8 bits (68), Expect = 6.0
Identities = 52/230 (22%), Positives = 91/230 (39%), Gaps = 25/230 (10%)
Query: 659 AQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLE 718
A + Q + + + R+ + + E ++ + Q+VE+E+ + +L + N++L
Sbjct: 16 ALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGT--NLKRENQRLM 73
Query: 719 SVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIA 778
+ E E + LQ ES + +S KQIE KL + LK
Sbjct: 74 EICESLEKTKQKISHELQVKESQVNFQEG---QLNSGKKQIE---KLEQELKR------- 120
Query: 779 QLIEKEEQRKEVQNQLVDREHKLANLHQK---TKVQEEKIKTLQKEREDKEETIDILRKE 835
+ E +R + Q D N QK T + + + K ED +E + +E
Sbjct: 121 --CKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSK-YEDLKEKYNKEVEE 177
Query: 836 LSRTEQIRKELSIKASSLEVQKAQLE----GRLEEKESLVKLQQEELNKH 881
R E K L K +S + +A + R + S+ QQE+ H
Sbjct: 178 RKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSH 227
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,719,466
Number of Sequences: 37866
Number of extensions: 1251954
Number of successful extensions: 16287
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 447
Number of HSP's successfully gapped in prelim test: 1023
Number of HSP's that attempted gapping in prelim test: 6887
Number of HSP's gapped (non-prelim): 5291
length of query: 905
length of database: 18,247,518
effective HSP length: 111
effective length of query: 794
effective length of database: 14,044,392
effective search space: 11151247248
effective search space used: 11151247248
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.