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Search of human proteins with 189163504
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189163504 serine peptidase inhibitor, Kazal type 5 isoform c
precursor [Homo sapiens]
(916 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189163504 serine peptidase inhibitor, Kazal type 5 isoform c ... 1907 0.0
gi|74027261 serine peptidase inhibitor, Kazal type 5 isoform b p... 1901 0.0
gi|189163501 serine peptidase inhibitor, Kazal type 5 isoform a ... 1901 0.0
gi|54873613 agrin [Homo sapiens] 75 2e-13
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 57 6e-08
gi|148746195 trichohyalin [Homo sapiens] 56 1e-07
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 54 7e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 54 9e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 52 3e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 51 6e-06
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 51 6e-06
gi|68299793 serine protease inhibitor, Kazal type 6 [Homo sapiens] 51 6e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 7e-06
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 50 1e-05
gi|45505132 serine protease inhibitor, Kazal type 1 precursor [H... 50 1e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 49 2e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 48 4e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 48 5e-05
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 48 5e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 6e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 8e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 8e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 47 1e-04
gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo ... 47 1e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 46 1e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 46 1e-04
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 46 2e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 46 2e-04
gi|94536774 serine peptidase inhibitor, Kazal type 9 [Homo sapiens] 45 3e-04
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 45 4e-04
>gi|189163504 serine peptidase inhibitor, Kazal type 5 isoform c
precursor [Homo sapiens]
Length = 916
Score = 1907 bits (4939), Expect = 0.0
Identities = 916/916 (100%), Positives = 916/916 (100%)
Query: 1 MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI 60
MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI
Sbjct: 1 MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI 60
Query: 61 NKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCG 120
NKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCG
Sbjct: 61 NKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCG 120
Query: 121 TDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTREND 180
TDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTREND
Sbjct: 121 TDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTREND 180
Query: 181 PVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCT 240
PVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCT
Sbjct: 181 PVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCT 240
Query: 241 RESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQY 300
RESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQY
Sbjct: 241 RESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQY 300
Query: 301 QNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKA 360
QNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKA
Sbjct: 301 QNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKA 360
Query: 361 TSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK 420
TSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK
Sbjct: 361 TSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK 420
Query: 421 SRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE 480
SRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE
Sbjct: 421 SRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE 480
Query: 481 ERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEE 540
ERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEE
Sbjct: 481 ERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEE 540
Query: 541 EEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTC 600
EEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTC
Sbjct: 541 EEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTC 600
Query: 601 SMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKT 660
SMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKT
Sbjct: 601 SMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKT 660
Query: 661 HGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLS 720
HGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLS
Sbjct: 661 HGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLS 720
Query: 721 CTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQ 780
CTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQ
Sbjct: 721 CTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQ 780
Query: 781 MKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGE 840
MKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGE
Sbjct: 781 MKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGE 840
Query: 841 RSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKD 900
RSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKD
Sbjct: 841 RSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKD 900
Query: 901 EEKSSSKPSNNAKVIY 916
EEKSSSKPSNNAKVIY
Sbjct: 901 EEKSSSKPSNNAKVIY 916
>gi|74027261 serine peptidase inhibitor, Kazal type 5 isoform b
precursor [Homo sapiens]
Length = 1064
Score = 1901 bits (4924), Expect = 0.0
Identities = 913/913 (100%), Positives = 913/913 (100%)
Query: 1 MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI 60
MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI
Sbjct: 1 MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI 60
Query: 61 NKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCG 120
NKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCG
Sbjct: 61 NKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCG 120
Query: 121 TDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTREND 180
TDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTREND
Sbjct: 121 TDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTREND 180
Query: 181 PVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCT 240
PVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCT
Sbjct: 181 PVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCT 240
Query: 241 RESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQY 300
RESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQY
Sbjct: 241 RESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQY 300
Query: 301 QNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKA 360
QNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKA
Sbjct: 301 QNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKA 360
Query: 361 TSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK 420
TSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK
Sbjct: 361 TSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK 420
Query: 421 SRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE 480
SRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE
Sbjct: 421 SRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE 480
Query: 481 ERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEE 540
ERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEE
Sbjct: 481 ERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEE 540
Query: 541 EEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTC 600
EEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTC
Sbjct: 541 EEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTC 600
Query: 601 SMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKT 660
SMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKT
Sbjct: 601 SMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKT 660
Query: 661 HGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLS 720
HGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLS
Sbjct: 661 HGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLS 720
Query: 721 CTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQ 780
CTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQ
Sbjct: 721 CTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQ 780
Query: 781 MKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGE 840
MKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGE
Sbjct: 781 MKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGE 840
Query: 841 RSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKD 900
RSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKD
Sbjct: 841 RSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKD 900
Query: 901 EEKSSSKPSNNAK 913
EEKSSSKPSNNAK
Sbjct: 901 EEKSSSKPSNNAK 913
Score = 795 bits (2054), Expect = 0.0
Identities = 417/926 (45%), Positives = 573/926 (61%), Gaps = 51/926 (5%)
Query: 19 DAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQK 78
+ S N +Q++C F+ F+++G+L C ++ DG NKCA C + KEA++ K
Sbjct: 150 ECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAELFLKEAENAK 209
Query: 79 RARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAE--- 135
R A C +++K R+G C + V G DG+ + N+CALCAE
Sbjct: 210 REGETRIRRNAEKDF---CKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFK 266
Query: 136 ------NAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKT 189
N+KT +G K+E + K +CS ++ ++G L CTRENDP+ GPDGK
Sbjct: 267 QRFSEENSKTDQNLG-KAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKM 325
Query: 190 HGNKCAMCAELFLKEAENAKR-EGETRIRRNAEK-----DFCKEYEKQVRNGRLFCTRES 243
HGN C+MC F E E K+ E R +R + K + C EY K VRNG+L CTRE+
Sbjct: 326 HGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTREN 385
Query: 244 DPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQ 303
DP++GPDG++HGN C++C F+ E+ K ++ K + K+ E +LCS+Y+
Sbjct: 386 DPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFE--ELCSEYRKS 443
Query: 304 AKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSY 363
KNG LFCTRENDPI+GPDGKMHGN CSMC+A+FQ E ARA+ KRE+ K
Sbjct: 444 RKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEER------ARAKAKREAAK---- 493
Query: 364 AELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKK-KEGKSR 422
E+CSE+R VRNG L CTRE++P++GPDGK+HGN C+MC F+ EEEEKK KE K +
Sbjct: 494 -EICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGK 552
Query: 423 NKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE-- 480
+ + + +ELCSEYR +NGRL CTRENDPI+G DGK+HGNTCSMCEAFFQQE
Sbjct: 553 VEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAK 612
Query: 481 --ERA--RAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVF 536
ERA RAK KREA KE C EFR ++NG L CTRE++PVRGPDGK HGNKCAMC +VF
Sbjct: 613 EKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVF 672
Query: 537 KLEEEEKKNDKEEKGKVEAEKVKREA----VQELCSEYRHYVRNGRLPCTRENDPIEGLD 592
+ E EE+K +EE + A Q+ C+EYR ++NGRL CTRE+DP+ D
Sbjct: 673 QKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDAD 732
Query: 593 GKIHGNTCSMCEAFFQQEAKEK-ERAEPRAK-VKREAEKETCDEFRRLLQNGKLFCTREN 650
GK + N C+MC+A ++EA+ K E + R+ E+ K+TCDEFR ++NGKL CTRE+
Sbjct: 733 GKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRES 792
Query: 651 DPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEY 710
DPVRGPDGKTHGNKC MCK ++E E+K+KE+ED+ N ++G + +D C E+
Sbjct: 793 DPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREF 852
Query: 711 REQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESG 770
R +NG+L CTRE++PVR GK + N+C MC++ +REA + + +S+ S +
Sbjct: 853 RSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNA 912
Query: 771 KDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDED-- 828
KD C EFR+ ++N +LIC RE+DPV G DGK + NKC MC+ EA E+ K +++
Sbjct: 913 KDECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAVFLTEALERAKLQEKPSH 972
Query: 829 -RSNTGERSNTGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQS 887
R++ E S S D E +C+++R + R G L C ++ PV G G+ + N C +C
Sbjct: 973 VRASQEEDSPDSFSSLDSE-MCKDYRVLPRIGYL-CPKDLKPVCGDDGQTYNNPCMLCHE 1030
Query: 888 IFDREANER-KKKDEEKSSSKPSNNA 912
R+ N + + + SS P A
Sbjct: 1031 NLIRQTNTHIRSTGKCEESSTPGTTA 1056
Score = 272 bits (696), Expect = 9e-73
Identities = 156/441 (35%), Positives = 230/441 (52%), Gaps = 39/441 (8%)
Query: 23 KNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQKRARH 82
+ ++E C EF+ ++NGKLFC ++ + DG NKCA CK + +KE + +KR
Sbjct: 625 REAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEE 684
Query: 83 LARAPKAT--------APTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCA 134
+ A T+ C ++++ ++G C + V DGK+Y+N+C +C
Sbjct: 685 EDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMC- 743
Query: 135 ENAKTGSQIGVKSEGECKSSNPE-----QDVCSAFRPFVRDGRLGCTRENDPVLGPDGKT 189
AK + K+E SN +D C FR +++G+L CTRE+DPV GPDGKT
Sbjct: 744 -KAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKT 802
Query: 190 HGNKCAMCAELFLKEA-ENAKREGETRI----------RRNAEKDFCKEYEKQVRNGRLF 238
HGNKC MC E +EA E K+E E R R N ++D C+E+ RNG+L
Sbjct: 803 HGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLI 862
Query: 239 CTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCS 298
CTRE++PVRGP G+MH NKCA+C IF R + E K D+ ++ K E CS
Sbjct: 863 CTRENNPVRGPYGKMHINKCAMCQSIF-DREANERKKKDEEKSSSKPSNNAKDE----CS 917
Query: 299 QYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESG 358
+++N +N L C RENDP+ G DGK + N C MC+A F E E+ K + + + R S
Sbjct: 918 EFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAVFLTEALERAKLQEKPSHVRASQ 977
Query: 359 KATSY-------AELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEE 411
+ S +E+C +YR L R G L C ++ P+ G DG+ + N C +C +
Sbjct: 978 EEDSPDSFSSLDSEMCKDYRVLPRIGYL-CPKDLKPVCGDDGQTYNNPCMLCHENLIRQT 1036
Query: 412 EEKKKKEGKSRNKRQSKSTAS 432
+ GK +TA+
Sbjct: 1037 NTHIRSTGKCEESSTPGTTAA 1057
Score = 87.0 bits (214), Expect = 7e-17
Identities = 44/153 (28%), Positives = 78/153 (50%), Gaps = 11/153 (7%)
Query: 24 NEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEA----KSQKR 79
N ++ C EF+ +++N +L CP++ DG + NKC C+ + EA K Q++
Sbjct: 910 NNAKDECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAVFLTEALERAKLQEK 969
Query: 80 ARHLARAPKATAPTELN------CDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALC 133
H+ + + +P + C D++ R G ++CP + VCG DG+TY+N C LC
Sbjct: 970 PSHVRASQEEDSPDSFSSLDSEMCKDYRVLPRIG-YLCPKDLKPVCGDDGQTYNNPCMLC 1028
Query: 134 AENAKTGSQIGVKSEGECKSSNPEQDVCSAFRP 166
EN + ++S G+C+ S+ ++ P
Sbjct: 1029 HENLIRQTNTHIRSTGKCEESSTPGTTAASMPP 1061
>gi|189163501 serine peptidase inhibitor, Kazal type 5 isoform a
precursor [Homo sapiens]
Length = 1094
Score = 1901 bits (4924), Expect = 0.0
Identities = 913/913 (100%), Positives = 913/913 (100%)
Query: 1 MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI 60
MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI
Sbjct: 1 MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI 60
Query: 61 NKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCG 120
NKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCG
Sbjct: 61 NKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCG 120
Query: 121 TDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTREND 180
TDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTREND
Sbjct: 121 TDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTREND 180
Query: 181 PVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCT 240
PVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCT
Sbjct: 181 PVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCT 240
Query: 241 RESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQY 300
RESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQY
Sbjct: 241 RESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQY 300
Query: 301 QNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKA 360
QNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKA
Sbjct: 301 QNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKA 360
Query: 361 TSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK 420
TSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK
Sbjct: 361 TSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK 420
Query: 421 SRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE 480
SRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE
Sbjct: 421 SRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE 480
Query: 481 ERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEE 540
ERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEE
Sbjct: 481 ERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEE 540
Query: 541 EEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTC 600
EEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTC
Sbjct: 541 EEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTC 600
Query: 601 SMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKT 660
SMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKT
Sbjct: 601 SMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKT 660
Query: 661 HGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLS 720
HGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLS
Sbjct: 661 HGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLS 720
Query: 721 CTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQ 780
CTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQ
Sbjct: 721 CTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQ 780
Query: 781 MKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGE 840
MKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGE
Sbjct: 781 MKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGE 840
Query: 841 RSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKD 900
RSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKD
Sbjct: 841 RSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKD 900
Query: 901 EEKSSSKPSNNAK 913
EEKSSSKPSNNAK
Sbjct: 901 EEKSSSKPSNNAK 913
Score = 780 bits (2013), Expect = 0.0
Identities = 417/956 (43%), Positives = 573/956 (59%), Gaps = 81/956 (8%)
Query: 19 DAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQK 78
+ S N +Q++C F+ F+++G+L C ++ DG NKCA C + KEA++ K
Sbjct: 150 ECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAELFLKEAENAK 209
Query: 79 RARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAE--- 135
R A C +++K R+G C + V G DG+ + N+CALCAE
Sbjct: 210 REGETRIRRNAEKDF---CKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFK 266
Query: 136 ------NAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKT 189
N+KT +G K+E + K +CS ++ ++G L CTRENDP+ GPDGK
Sbjct: 267 QRFSEENSKTDQNLG-KAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKM 325
Query: 190 HGNKCAMCAELFLKEAENAKR-EGETRIRRNAEK-----DFCKEYEKQVRNGRLFCTRES 243
HGN C+MC F E E K+ E R +R + K + C EY K VRNG+L CTRE+
Sbjct: 326 HGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTREN 385
Query: 244 DPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQ 303
DP++GPDG++HGN C++C F+ E+ K ++ K + K+ E +LCS+Y+
Sbjct: 386 DPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFE--ELCSEYRKS 443
Query: 304 AKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSY 363
KNG LFCTRENDPI+GPDGKMHGN CSMC+A+FQ E ARA+ KRE+ K
Sbjct: 444 RKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEER------ARAKAKREAAK---- 493
Query: 364 AELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKK-KEGKSR 422
E+CSE+R VRNG L CTRE++P++GPDGK+HGN C+MC F+ EEEEKK KE K +
Sbjct: 494 -EICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGK 552
Query: 423 NKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQE-- 480
+ + + +ELCSEYR +NGRL CTRENDPI+G DGK+HGNTCSMCEAFFQQE
Sbjct: 553 VEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAK 612
Query: 481 --ERA--RAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVF 536
ERA RAK KREA KE C EFR ++NG L CTRE++PVRGPDGK HGNKCAMC +VF
Sbjct: 613 EKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVF 672
Query: 537 KLEEEEKKNDKEEKGKVEAEKVKREA----VQELCSEYRHYVRNGRLPCTRENDPIEGLD 592
+ E EE+K +EE + A Q+ C+EYR ++NGRL CTRE+DP+ D
Sbjct: 673 QKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDAD 732
Query: 593 GKIHGNTCSMCEAFFQQEAKEK-ERAEPRAK-VKREAEKETCDEFRRLLQNGKLFCTREN 650
GK + N C+MC+A ++EA+ K E + R+ E+ K+TCDEFR ++NGKL CTRE+
Sbjct: 733 GKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRES 792
Query: 651 DPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEY 710
DPVRGPDGKTHGNKC MCK ++E E+K+KE+ED+ N ++G + +D C E+
Sbjct: 793 DPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREF 852
Query: 711 REQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESG 770
R +NG+L CTRE++PVR GK + N+C MC++ +REA + + +S+ S +
Sbjct: 853 RSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNA 912
Query: 771 KDTC------------------------------DEFRSQMKNGKLICTRESDPVRGPDG 800
KD C EFR+ ++N +LIC RE+DPV G DG
Sbjct: 913 KDQCRQVQNEAEDAKFRQPGRSLASVARMSTDECSEFRNYIRNNELICPRENDPVHGADG 972
Query: 801 KTHGNKCTMCKEKLEREAAEKKKKEDED---RSNTGERSNTGERSNDKEDLCREFRSMQR 857
K + NKC MC+ EA E+ K +++ R++ E S S D E +C+++R + R
Sbjct: 973 KFYTNKCYMCRAVFLTEALERAKLQEKPSHVRASQEEDSPDSFSSLDSE-MCKDYRVLPR 1031
Query: 858 NGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANER-KKKDEEKSSSKPSNNA 912
G L C ++ PV G G+ + N C +C R+ N + + + SS P A
Sbjct: 1032 IGYL-CPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTA 1086
Score = 262 bits (670), Expect = 9e-70
Identities = 156/466 (33%), Positives = 232/466 (49%), Gaps = 59/466 (12%)
Query: 23 KNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQKRARH 82
+ ++E C EF+ ++NGKLFC ++ + DG NKCA CK + +KE + +KR
Sbjct: 625 REAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEE 684
Query: 83 LARAPKAT--------APTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCA 134
+ A T+ C ++++ ++G C + V DGK+Y+N+C +C
Sbjct: 685 EDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMC- 743
Query: 135 ENAKTGSQIGVKSEGECKSSNPE-----QDVCSAFRPFVRDGRLGCTRENDPVLGPDGKT 189
AK + K+E SN +D C FR +++G+L CTRE+DPV GPDGKT
Sbjct: 744 -KAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKT 802
Query: 190 HGNKCAMCAELFLKEA-ENAKREGETRI----------RRNAEKDFCKEYEKQVRNGRLF 238
HGNKC MC E +EA E K+E E R R N ++D C+E+ RNG+L
Sbjct: 803 HGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLI 862
Query: 239 CTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLG----------------K 282
CTRE++PVRGP G+MH NKCA+C IF + +E K ++ +
Sbjct: 863 CTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNAKDQCRQVQNE 922
Query: 283 AEEK---------TKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMC 333
AE+ V R CS+++N +N L C RENDP+ G DGK + N C MC
Sbjct: 923 AEDAKFRQPGRSLASVARMSTDECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMC 982
Query: 334 QAYFQAENEEKKKAEARARNKRESGKATSY-------AELCSEYRKLVRNGKLACTREND 386
+A F E E+ K + + + R S + S +E+C +YR L R G L C ++
Sbjct: 983 RAVFLTEALERAKLQEKPSHVRASQEEDSPDSFSSLDSEMCKDYRVLPRIGYL-CPKDLK 1041
Query: 387 PIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTAS 432
P+ G DG+ + N C +C + + GK +TA+
Sbjct: 1042 PVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTAA 1087
Score = 85.1 bits (209), Expect = 3e-16
Identities = 43/147 (29%), Positives = 75/147 (51%), Gaps = 11/147 (7%)
Query: 30 CHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEA----KSQKRARHLAR 85
C EF+ +++N +L CP++ DG + NKC C+ + EA K Q++ H+
Sbjct: 946 CSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAVFLTEALERAKLQEKPSHVRA 1005
Query: 86 APKATAPTELN------CDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKT 139
+ + +P + C D++ R G ++CP + VCG DG+TY+N C LC EN
Sbjct: 1006 SQEEDSPDSFSSLDSEMCKDYRVLPRIG-YLCPKDLKPVCGDDGQTYNNPCMLCHENLIR 1064
Query: 140 GSQIGVKSEGECKSSNPEQDVCSAFRP 166
+ ++S G+C+ S+ ++ P
Sbjct: 1065 QTNTHIRSTGKCEESSTPGTTAASMPP 1091
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 75.5 bits (184), Expect = 2e-13
Identities = 163/801 (20%), Positives = 259/801 (32%), Gaps = 138/801 (17%)
Query: 111 CPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRD 170
CP VCG+D TY N C L +I + S G C S +P +V +F
Sbjct: 202 CPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCAR 261
Query: 171 GRLGCTRE-----------NDPVLGPDGKTHGNKCAMCAELFLKEAENAKR-EGETRIRR 218
G T V G DG + +C + ++ K+ +G +
Sbjct: 262 SADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQ 321
Query: 219 NAEKD---FCKEYEKQVRNGRLF----CTRESDPVRGPDGRMHGNKCALCAEIFKQRFSE 271
A D C+ + R L C PV G DG + N C + +
Sbjct: 322 GALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLL 381
Query: 272 ENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCS 331
+ ++ Q G+ + + V L + + + + C P+ DG+ + + C
Sbjct: 382 QKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCW 441
Query: 332 MCQAYFQAENEEKKKAEARARNKRES--GKATSYAELCSEYRKLVRNGKL------ACTR 383
QA + + K + G ++ C+ V+NG+ AC+
Sbjct: 442 RQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCA-----VKNGQAACECLQACSS 496
Query: 384 ENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKS 443
DP+ G DG +G+ C + E + ++G Q + F LC
Sbjct: 497 LYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQCR----FGALC-----E 547
Query: 444 RKNGRLFCTRE----NDPIQGPDGKMHGNTCSM--CEAFFQQEERARAKAKREAAKEICS 497
+ GR C E P+ G DG + + C + Q + E +
Sbjct: 548 AETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVC 607
Query: 498 EFRDQVRNGTLICTR-EH---NPVRGPDGKMHGNKC----AMCASVFKLEE------EEK 543
F G +C R EH PV G DG +G+ C A C ++EE E+
Sbjct: 608 AFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQA 667
Query: 544 KNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPC-----TRENDPIEGLDGKIHGN 598
+ G E ++E ++ + +G C + P+ G DG +
Sbjct: 668 ECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYST 727
Query: 599 TCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDG 658
C E +K C+ R L + C P
Sbjct: 728 EC-------------------------ELKKARCESQRGLYVAAQGACRGPTFAPLPPVA 762
Query: 659 KTHGNKCAMCKAVFQKENEERKRKEE----EDQRNAAGHGSSGGG--------------G 700
H CA ++N R HGS GG G
Sbjct: 763 PLH---CAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVG 819
Query: 701 GNTQDECA----EYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNE 756
G D C +R + +GR CT S + A +C K + +
Sbjct: 820 GLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQ 879
Query: 757 YSRSRSNG-TGSE---SGKDTCDEFRSQM------KNGKLICT--------RESDPVRGP 798
R+ G G E S TC E R + ++G C + V G
Sbjct: 880 CPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGS 939
Query: 799 DGKTHGNKCTM----CKEKLE 815
DG T+GN+C + C++ L+
Sbjct: 940 DGVTYGNECQLKTIACRQGLQ 960
Score = 56.2 bits (134), Expect = 1e-07
Identities = 111/568 (19%), Positives = 194/568 (34%), Gaps = 103/568 (18%)
Query: 317 PIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKAT-SYAELCSEYRK-LV 374
P+ G D + N C + +A + + + ++ T S+ C+ L
Sbjct: 208 PVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLT 267
Query: 375 RNGKLACTRENDP---IQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTA 431
+ T P + G DG + C + +E KK +G + +
Sbjct: 268 ASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDP 327
Query: 432 SFEELCSEYRKSRKNGRLF----CTRENDPIQGPDGKMHGNTCSM-----CEAFFQQEER 482
S C ++R+ L C P+ G DG + N C M Q+ R
Sbjct: 328 S--RSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVR 385
Query: 483 ARAKAKREAAKEICS--------EFRDQVRNGTLICTREHNPVRGPDGKMHGNKC----A 530
+ R+ E C R + + C + PV DG+ + + C A
Sbjct: 386 SGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQA 445
Query: 531 MCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQ----ELCSEYRHYVRNGRLPC----- 581
C +++ + +G + VQ C+ V+NG+ C
Sbjct: 446 EC-------RQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCA-----VKNGQAACECLQA 493
Query: 582 -TRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRR--- 637
+ DP+ G DG +G+ C + EA +E +V R+ + C + R
Sbjct: 494 CSSLYDPVCGSDGVTYGSACEL-EATACTLGRE-------IQVARKGPCDRCGQCRFGAL 545
Query: 638 -LLQNGKLFCTRE----NDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAG 692
+ G+ C E PV G DG T+ ++C + +
Sbjct: 546 CEAETGRCVCPSECVALAQPVCGSDGHTYPSECML--------------HVHACTHQISL 591
Query: 693 HGSSGGGGGNTQDECAEYREQMKNGRLSCTR----ESDPVRDADGKSYNNQCTM----CK 744
H +S G D + G+ C R PV +DG +Y + C + C
Sbjct: 592 HVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACL 651
Query: 745 AKLEREAERKNEYSRSRSNGTGSESGKD-TCDE---------FRSQMKNGKLIC-----T 789
+ + E R ++ GS SG+D C++ + ++G +C +
Sbjct: 652 QQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQS 711
Query: 790 RESDPVRGPDGKTHGNKCTMCKEKLERE 817
PV G DG T+ +C + K + E +
Sbjct: 712 VPGSPVCGSDGVTYSTECELKKARCESQ 739
Score = 42.7 bits (99), Expect = 0.002
Identities = 78/376 (20%), Positives = 125/376 (33%), Gaps = 63/376 (16%)
Query: 457 PIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNP 516
P+ G D + N C + A Q+ R R ++ RD N T C+
Sbjct: 208 PVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGS------RDPCSNVT--CSFGSTC 259
Query: 517 VRGPDGKMHGNKC-AMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVR 575
R DG C A C +G E + ++Y +
Sbjct: 260 ARSADGLTASCLCPATC-----------------RGAPEGTVCGSDG-----ADYPGECQ 297
Query: 576 NGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEF 635
R C R+ + + DG C C+ ++ R PR + +
Sbjct: 298 LLRRACARQENVFKKFDGP-----CDPCQGALPDPSRSC-RVNPRTRRPEMLLRPESCPA 351
Query: 636 RRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGS 695
R+ G T END V G G G + + V + + R + E + NA
Sbjct: 352 RQAPVCGDDGVTYENDCVMGRSGAARG---LLLQKVRSGQCQGRDQCPEPCRFNAVCLSR 408
Query: 696 SGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKN 755
G R + R++C PV DG++Y++ C +A+ ++ +
Sbjct: 409 RG-------------RPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPS 455
Query: 756 EYSRSRSNGTGSESGKDTCDEFRSQMKNGKLIC------TRESDPVRGPDGKTHGNKC-- 807
++ G +KNG+ C + DPV G DG T+G+ C
Sbjct: 456 KHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACEL 515
Query: 808 --TMCKEKLEREAAEK 821
T C E + A K
Sbjct: 516 EATACTLGREIQVARK 531
Score = 38.1 bits (87), Expect = 0.038
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Query: 111 CPDYYEA-VCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSS 154
CP+ VCG+DG TY N C L + G QI ++S G C+ +
Sbjct: 928 CPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEA 972
Score = 35.4 bits (80), Expect = 0.25
Identities = 58/269 (21%), Positives = 93/269 (34%), Gaps = 34/269 (12%)
Query: 580 PCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLL 639
PC P+ G D + N C + A Q+ + + + + TC
Sbjct: 201 PCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCA 260
Query: 640 QN-----GKLFC--TRENDP---VRGPDGKTHGNKCAMC-KAVFQKENEERKRKEEEDQR 688
++ C T P V G DG + +C + +A ++EN +K D
Sbjct: 261 RSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPC 320
Query: 689 NAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLE 748
A S N + R +M SC PV DG +Y N C M ++
Sbjct: 321 QGALPDPSRSCRVNPRTR----RPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRS--- 373
Query: 749 REAERKNEYSRSRSNGTGSESGKDTCDE------------FRSQMKNGKLICTRESDPVR 796
A R + RS G G+D C E R + ++ C PV
Sbjct: 374 -GAARGLLLQKVRS---GQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVC 429
Query: 797 GPDGKTHGNKCTMCKEKLEREAAEKKKKE 825
DG+T+ + C + + ++ A K +
Sbjct: 430 AQDGRTYDSDCWRQQAECRQQRAIPSKHQ 458
Score = 31.6 bits (70), Expect = 3.5
Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 1/56 (1%)
Query: 98 DDFKKGERDGDFICPDYYEA-VCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECK 152
+D + G DF C + VCG+DG TY C L ++ + V ++G C+
Sbjct: 696 EDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACR 751
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 57.4 bits (137), Expect = 6e-08
Identities = 117/526 (22%), Positives = 212/526 (40%), Gaps = 90/526 (17%)
Query: 262 AEIFKQRFSEENSKTDQNLGKAEE-----KTKVKREIVKLCSQYQNQAKNGILFCTREND 316
AE+ KQR E+ +T++ + E K K++RE+ K Q ++ G + E D
Sbjct: 107 AEMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRELAKRAEQIEDINNTGTESASEEGD 166
Query: 317 --------PIRG--PDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAEL 366
P++ GKM N + +K+ E + R K E K Y
Sbjct: 167 DSLLITVVPVKSYKTSGKMKKNF-----------EDLEKEREEKERIKYEEDKRIRY--- 212
Query: 367 CSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAE---EEEKKKKEGKSRN 423
E R ++ K +D I+ K + + F + E +E +KK+ +
Sbjct: 213 -EEQRPSLKEAKCLSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQENRKKQAEEEAR 271
Query: 424 KRQSKSTASFEE----LCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQ 479
KR + +FEE + +E +++ ++F GK+ S E Q+
Sbjct: 272 KRLEEEKRAFEEARRQMVNEDEENQDTAKIFKGYR-------PGKL---KLSFEEMERQR 321
Query: 480 EERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRG--------PDGKMHGNKCAM 531
E + KA+ EA + I E + + + +P GK+ N +
Sbjct: 322 REDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEFLTPGKLEINFEEL 381
Query: 532 CASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGL 591
K+EEE+++ ++E K K+E EK + E +++ E N +RE + + L
Sbjct: 382 LKQ--KMEEEKRRTEEERKHKLEMEKQEFEQLRQEMGEEEE--ENETFGLSREYEELIKL 437
Query: 592 --DGKIHG-NTCSMCEAFFQ------QEAKEKERAEPRA---KVK-REAE---KETCDEF 635
G I N S E Q Q+ E+ERA RA ++K REAE +E +
Sbjct: 438 KRSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERARRRAIDLEIKEREAENFHEEDDVDV 497
Query: 636 RRLLQNGKLFCTREN--------DPVRGPDGKTHGNKCAMCKAVFQKEN----EERKRKE 683
R ++ F + N R + + + + + F++ ++KR+E
Sbjct: 498 RPARKSEAPFTHKVNMKARFEQMAKAREEEEQRRIEEQKLLRMQFEQREIDAALQKKREE 557
Query: 684 EEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVR 729
EE++ + +GS+ T+ +++ +KN + +S+PVR
Sbjct: 558 EEEEEGSIMNGSTAEDEEQTRSGAPWFKKPLKN---TSVVDSEPVR 600
Score = 37.4 bits (85), Expect = 0.065
Identities = 53/210 (25%), Positives = 79/210 (37%), Gaps = 32/210 (15%)
Query: 673 QKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKN----GRLSCTRESDP- 727
Q++ E+RKR EEE +R Q E A+ EQ+++ G S + E D
Sbjct: 112 QRQEEQRKRTEEERKRRIEQDMLE---KRKIQRELAKRAEQIEDINNTGTESASEEGDDS 168
Query: 728 --VRDADGKSYNNQCTMCK--AKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKN 783
+ KSY M K LE+E E K E + +E R +K
Sbjct: 169 LLITVVPVKSYKTSGKMKKNFEDLEKEREEKERIKY-------EEDKRIRYEEQRPSLKE 221
Query: 784 GKLICTRESDPVRGPDGK--THGNKCTMCKEKLEREAAEKKKK----------EDEDRSN 831
K + D + K K + E+LER+ E +KK E+E R+
Sbjct: 222 AKCLSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQENRKKQAEEEARKRLEEEKRAF 281
Query: 832 TGERSNTGERSNDKEDLCREFRSMQRNGKL 861
R + +D + F+ R GKL
Sbjct: 282 EEARRQMVNEDEENQDTAKIFKG-YRPGKL 310
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 56.2 bits (134), Expect = 1e-07
Identities = 145/686 (21%), Positives = 250/686 (36%), Gaps = 156/686 (22%)
Query: 201 FLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCAL 260
FL E E ++ R R E F +E E+ R R +E + DG +
Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE-----DGLQEDQE--- 861
Query: 261 CAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRG 320
+R S+E + + + EE+ K +R + Q Q + E + ++
Sbjct: 862 ------RRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
Query: 321 PDGKMHGNLCSMCQ----AYFQAENE-------EKKKAEARARNKRESGKATSYAE--LC 367
+ + Q Q E E EK++ + R R R+ K E L
Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG 975
Query: 368 SEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQS 427
E K R + RE + +Q + E + E E+++++E + + +++
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEE-----------EQLLREEREKRRRQEWERQYRKKD 1024
Query: 428 KSTASFEELCSEYRKSRK-NGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAK 486
+ E+L E R+ R+ R RE + +Q + ++ G ++E R R +
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE---------ERETRRRQE 1075
Query: 487 AKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKND 546
+R+ KE ++++ RE P+ + + C EEEE + +
Sbjct: 1076 LERQYRKE------EELQQEEEQLLREE-----PEKRRRQERERQCR-----EEEELQQE 1119
Query: 547 KEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAF 606
+E+ + E EK +R QEL +YR E
Sbjct: 1120 EEQLLREEREKRRR---QELERQYRE-------------------------------EEE 1145
Query: 607 FQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCA 666
QQE ++ R EP + ++E E++ +E LQ + RE R
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEE--LQQEEEQLLREEQEKR------------ 1191
Query: 667 MCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESD 726
++E E + R+EEE QR Q YR++ + L E +
Sbjct: 1192 ------RQERERQYREEEELQR---------------QKRKQRYRDEDQRSDLKWQWEPE 1230
Query: 727 PVRDA-DGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGK 785
D K Y CK + E E R+ E S+ R +S +D Q +
Sbjct: 1231 KENAVRDNKVY------CKGR-ENEQFRQLEDSQLRDR----QSQQDLQHLLGEQQERD- 1278
Query: 786 LICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDK 845
RE + R H + +E+LERE E+K+ + DR + E+ E +K
Sbjct: 1279 ----REQERRRWQQRDRHFPE----EEQLERE--EQKEAKRRDRKSQEEKQLLREEREEK 1328
Query: 846 EDLCREFRSMQRNGKLICTRENNPVR 871
R + +L+ RE P+R
Sbjct: 1329 RRRQETDRKFREEEQLLQEREEQPLR 1354
Score = 46.2 bits (108), Expect = 1e-04
Identities = 129/689 (18%), Positives = 253/689 (36%), Gaps = 120/689 (17%)
Query: 177 RENDPVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGR 236
+E + +LG + +T + E ++ E ++E E +R EK +E E+Q R
Sbjct: 1058 QEEEQLLGEERETRRRQEL---ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEE 1114
Query: 237 LFCTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKL 296
E +R + E+ +Q EE + ++ EE K +R+ ++
Sbjct: 1115 ELQQEEEQLLREEREKRRRQ------ELERQYREEEEVQQEEEQLLREEPEKRRRQELER 1168
Query: 297 CSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRE 356
+ + + + RE R + + E EE ++ + + R + E
Sbjct: 1169 QYREEEELQQEEEQLLREEQEKRRQERERQ-----------YREEEELQRQKRKQRYRDE 1217
Query: 357 SGKATSYAELCSEYRKLVRNGKLACT-RENDPI-QGPDGKVHGNTCSMCEVFFQAEEEEK 414
++ + E VR+ K+ C REN+ Q D ++ E++E+
Sbjct: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER 1277
Query: 415 KKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCE 474
+++ + R +++ + E+L E +K K D K S E
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRR--------------DRK------SQEE 1317
Query: 475 AFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGP--DGKMHGNKCAMC 532
+EER + ++E ++ FR++ + L+ RE P+R D K +
Sbjct: 1318 KQLLREEREEKRRRQETDRK----FREEEQ---LLQEREEQPLRRQERDRKFREEELRHQ 1370
Query: 533 ASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLD 592
K EEE++ ++E+ + K +E Q C E +R R RE +
Sbjct: 1371 EQGRKFLEEEQRLRRQERER----KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ 1426
Query: 593 GKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDP 652
+ + F++E ++ R E K E ++ + R+ + +L RE
Sbjct: 1427 ER---------DRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477
Query: 653 VRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYRE 712
+ ++ +RK EEE Q Q+ ++RE
Sbjct: 1478 LH-------------------RQERDRKFLEEEQQLRR-------------QERDRKFRE 1505
Query: 713 QMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKD 772
Q R +P R K + + + + +R+ ++ + R + G +D
Sbjct: 1506 QE-------LRSQEPER----KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 773 TCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDED--RS 830
+FR + + R+ + + K + ++K+ R+ E+K EDE R
Sbjct: 1555 R--KFREEEQ------LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRR 1606
Query: 831 NTGERSNTGERS---NDKEDLCREFRSMQ 856
G++ ER + E L +E Q
Sbjct: 1607 QEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Score = 36.6 bits (83), Expect = 0.11
Identities = 72/371 (19%), Positives = 144/371 (38%), Gaps = 58/371 (15%)
Query: 538 LEEEEKKNDKEEKGKVEAEKVKREAVQE--LCSEYRHYVRNGRLPCTR-ENDPIEGLDGK 594
L+EEE++ +EE+ K ++ +R+ +E L E +R R R E + D K
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
Query: 595 IHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVR 654
+ QQ+ ++ EP + ++E EK+ +E L Q + E + R
Sbjct: 966 L------------QQKEEQLLGEEPEKRRRQEREKKYREE-EELQQEEEQLLREEREKRR 1012
Query: 655 GPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQM 714
+ + K K Q+E E+ R+E E +R Q+ +YRE+
Sbjct: 1013 RQEWERQYRK----KDELQQEEEQLLREEREKRR--------------LQERERQYREEE 1054
Query: 715 KNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTC 774
+ +E + + + ++ Q +LER+ ++ E + E K
Sbjct: 1055 E-----LQQEEEQLLGEERETRRRQ------ELERQYRKEEELQQEEEQLLREEPEKRRR 1103
Query: 775 DEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGE 834
E Q + + + E +R K +++LER+ E+++ + E+ E
Sbjct: 1104 QERERQCREEEELQQEEEQLLREEREKRR-------RQELERQYREEEEVQQEEEQLLRE 1156
Query: 835 RSNTGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREAN 894
R + E RE +Q+ + + E R + + + R+
Sbjct: 1157 EPEK-RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE-----EEELQRQKR 1210
Query: 895 ERKKKDEEKSS 905
+++ +DE++ S
Sbjct: 1211 KQRYRDEDQRS 1221
Score = 35.4 bits (80), Expect = 0.25
Identities = 89/495 (17%), Positives = 184/495 (37%), Gaps = 69/495 (13%)
Query: 410 EEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNT 469
+EEE++++ K + + + E+ ++ R+ RL E + +Q
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ-------RL 532
Query: 470 CSMCEAFFQQEERARAKAKREAAKEICSEFRDQ-------VRNGTLICTREHNPVR--GP 520
S + +QEER KRE K + E R+Q R L+ E +
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
Query: 521 DGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEK--------VKREAVQELCSEYRH 572
+ + + V +LE+EE++ + ++ + E E+ + E Q+ +
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 573 YVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETC 632
R RL E + +E + H ++E +E+E AE + RE K
Sbjct: 653 ERREQRLKREEEEERLEQRLKREH-----------EEERREQELAEEEQEQARERIKSRI 701
Query: 633 DEFRRLLQN------GKLFC-TRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEE 685
+++ L++ K++ R+ + R + + + +Q+E ++++EE
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Query: 686 DQR-------NAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNN 738
+QR A G + + E RE+ RE + + + K
Sbjct: 762 EQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRR 821
Query: 739 QCTMCKAK----LERE------------AERKNEYSRSRSNGTGSESGKDTCDEFRSQMK 782
+ + K LE E E ++ + E +D ++ + +
Sbjct: 822 RQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEE 881
Query: 783 NGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERS 842
+ T + P + +E+L+RE EK+++++++R E +
Sbjct: 882 RKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE----QLQ 937
Query: 843 NDKEDLCREFRSMQR 857
++E L RE R +R
Sbjct: 938 QEEEQLLREEREKRR 952
Score = 35.0 bits (79), Expect = 0.32
Identities = 50/258 (19%), Positives = 101/258 (39%), Gaps = 24/258 (9%)
Query: 411 EEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTC 470
EEE+ +EG+ + R+ + F E + R+ + + +E ++ +
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL--QEEQQLRRQE-------- 1720
Query: 471 SMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCA 530
E F++EE+ R + ++E + +R + L RE +R + K
Sbjct: 1721 --LERKFREEEQLRQETEQEQLRR-QERYRKILEEEQLRPEREEQQLRRQE---RDRKFR 1774
Query: 531 MCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEG 590
+ + EE++ +E K E+ R+ +E + R R+G+ E +E
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE--QQLRPQQRDGKYRWEEEQLQLEE 1832
Query: 591 LDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRL------LQNGKL 644
+ ++ A Q +EK R E + + E +K + R+L Q +
Sbjct: 1833 QEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEE 1892
Query: 645 FCTRENDPVRGPDGKTHG 662
R+ ++ +GK HG
Sbjct: 1893 QRHRQVGEIKSQEGKGHG 1910
Score = 30.4 bits (67), Expect = 7.9
Identities = 90/462 (19%), Positives = 169/462 (36%), Gaps = 57/462 (12%)
Query: 410 EEEEKKKKEGKSRN-------KRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPD 462
+EE++++ E + R +R+ K EL +S K RL E Q D
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERL----EQRDRQRRD 170
Query: 463 GKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRD--QVRNGTLICTREHNPVRGP 520
++ E ++E RA + + EF D Q+R L+ R +G
Sbjct: 171 EELWRQRQEWQE---REERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRR----KGR 223
Query: 521 DGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQ---ELCSEYRHYVRNG 577
+ K + VF+ EEE++ +E + E EK++ E Q EL E +
Sbjct: 224 EEKQQQRRERQ-DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Query: 578 RLPCTRENDPIEGLDGKIHGNTC-----------SMCEAFFQQEAKEKERAEPRAKVKRE 626
R RE E ++ E QQE +E++ +++RE
Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 627 AEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEED 686
E+ + RR + + RE R + + + + Q E++ R+E++
Sbjct: 343 QEERREQQLRREQEEER----REQQLRREQEEERREQQ---LRREQQLRREQQLRREQQL 395
Query: 687 QRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSY--NNQCTMCK 744
+R + E REQ RE R+ + + + ++ +
Sbjct: 396 RREQ-----------QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
Query: 745 AKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHG 804
+L+RE E + ++ + E + R Q + + + + R +
Sbjct: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504
Query: 805 NKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKE 846
+ + +E+ ER K++E+E+R RS R +E
Sbjct: 505 QQ--LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 53.9 bits (128), Expect = 7e-07
Identities = 65/301 (21%), Positives = 124/301 (41%), Gaps = 20/301 (6%)
Query: 608 QQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAM 667
+Q KE+ R + R +RE E+E + R +G+ R+ D + + +T +
Sbjct: 115 RQREKERNRQKER---ERETEREG-ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ 170
Query: 668 CKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDP 727
+ QKE E K ++E +R + +++ RE+ R++D
Sbjct: 171 TERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDR 230
Query: 728 VRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLI 787
RD K+ + +A+ ER +ER+ E + R + +D R Q +
Sbjct: 231 ERDRQRKTEREREK--QAERERASERETERDKERERERDRDRDRD-----RRQKE----- 278
Query: 788 CTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKED 847
RE R +T ++ T K + +RE E++++ + R ER ER + E
Sbjct: 279 --RERQTDRKRQRRTERDRETERKRERQRER-ERERERNRKRERERERERERERQRETER 335
Query: 848 LCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDRE-ANERKKKDEEKSSS 906
+ R +R + RE N G G+ + + DR+ A ER++++ ++
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
Query: 907 K 907
+
Sbjct: 396 R 396
Score = 46.2 bits (108), Expect = 1e-04
Identities = 69/392 (17%), Positives = 149/392 (38%), Gaps = 47/392 (11%)
Query: 478 QQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFK 537
+Q+ER R + KR+ +E + R++ R R+ + R D + +
Sbjct: 58 RQKERERRREKRQTERETDRK-RERRREKDRHRKRDRHRERQRDREKERER--------- 107
Query: 538 LEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHG 597
+ +++ D++ + + +K + + R +G+ R+ D + + +
Sbjct: 108 --QTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDR 165
Query: 598 NTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPD 657
E Q+E + ++ + R + +R+ EKE E R + RE + R +
Sbjct: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG------RERERERETE 219
Query: 658 GKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNG 717
+T K +E + +++ E E ++ A +S ++ E
Sbjct: 220 TETER------KRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273
Query: 718 RLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEF 777
R RE R ++ ++ T K + +RE ER+ E +R R E ++ E
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333
Query: 778 -------RSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAA----------- 819
R + + + RE + G +G+ + + + +R++A
Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRD 393
Query: 820 -----EKKKKEDEDRSNTGERSNTGERSNDKE 846
E++++ ++DR E ER D+E
Sbjct: 394 RDRQKERERQTEKDRDGQRETEKQREREKDRE 425
Score = 45.1 bits (105), Expect = 3e-04
Identities = 101/494 (20%), Positives = 183/494 (37%), Gaps = 72/494 (14%)
Query: 343 EKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSM 402
EK++ E KRE + +R+ R+ + R+ D + + N
Sbjct: 67 EKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNR--- 123
Query: 403 CEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPD 462
Q E E + ++EG+ RQ+ E ++ + R+ + + +
Sbjct: 124 -----QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Query: 463 GKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDG 522
+ N +QE R R +R+ KE +E R R RE R +
Sbjct: 179 REREKN---------RQERRER---ERQREKENKTEDRHSERG------RERERERETET 220
Query: 523 KMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCT 582
+ + + +++ D++ K + E EK +A +E SE R R+
Sbjct: 221 ETERKR-----------QTDRERDRQRKTEREREK---QAERERASE-RETERDKERERE 265
Query: 583 RENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNG 642
R+ D K E Q + K + R E + +R+ E++ E R +N
Sbjct: 266 RDRDRDRDRRQK---------ERERQTDRKRQRRTERDRETERKRERQRERE-RERERNR 315
Query: 643 KLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGN 702
K RE + R +T ++ +KE E +++++ E R G G
Sbjct: 316 KRERERERERERERQRETERDR--------EKERERKRKRQTEMDRE---RNRQTGREGR 364
Query: 703 TQDECAEYREQMKNGRLSCTRES-DPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSR 761
Q E RE+ ++ + + RE + RD D + + T +RE E++ E + R
Sbjct: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424
Query: 762 SNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEK 821
+ G E G++ R + K + R++D G K + T+ R A
Sbjct: 425 ESERGRERGRE-----REKQKGRERDRERQTDRQAGRQRK----RSTLYVNPPPRTARSG 475
Query: 822 KKKEDEDRSNTGER 835
+ D +R G R
Sbjct: 476 VVQSDPNRPTRGIR 489
Score = 44.7 bits (104), Expect = 4e-04
Identities = 78/438 (17%), Positives = 164/438 (37%), Gaps = 47/438 (10%)
Query: 409 AEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGN 468
A+ +++++ K R +R+ K E R+ K+ R + + + +
Sbjct: 49 ADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQ 108
Query: 469 TCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNK 528
T + ++E + + +RE +E RD+ +G RE R D + +
Sbjct: 109 TDRERDRQREKERNRQKERERETERE-GERGRDRQTDGQ----RERERQR--DAEKERER 161
Query: 529 CAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPI 588
+ E +K + EK + E + +R+ +E +E RH R RE +
Sbjct: 162 QTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETET- 220
Query: 589 EGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTR 648
+ ++ K + E +A+ +R +E+ET + R R
Sbjct: 221 -------ETERKRQTDRERDRQRKTEREREKQAERERASERETERDKER---------ER 264
Query: 649 ENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECA 708
E D R D + + ++ + +R+R+ E D+ + +
Sbjct: 265 ERDRDRDRDRRQKERE--------RQTDRKRQRRTERDRETER----------KRERQRE 306
Query: 709 EYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSE 768
RE+ +N + RE + R+ ++ ++ + + ER+ +R+ E R R+ TG E
Sbjct: 307 RERERERNRKRERERERERERERQRETERDR----EKERERKRKRQTEMDRERNRQTGRE 362
Query: 769 SGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMC-KEKLEREAAEKKKKEDE 827
+ E + + + + R D + K++ + EK+++ ++
Sbjct: 363 GRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREK 422
Query: 828 DRSNTGERSNTGERSNDK 845
DR + R ER K
Sbjct: 423 DRESERGRERGREREKQK 440
Score = 42.0 bits (97), Expect = 0.003
Identities = 47/235 (20%), Positives = 93/235 (39%), Gaps = 23/235 (9%)
Query: 673 QKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDAD 732
QKE E R+ K + ++ + + + +RE+ ++ R++D RD
Sbjct: 59 QKERERRREKRQTERETDRKRERRREKDRHRKRD--RHRERQRDREKERERQTDRERDRQ 116
Query: 733 GKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRES 792
+ N+ + + ERE ER+ E R R G + D + + + R++
Sbjct: 117 REKERNR----QKERERETEREGERGRDRQTD-GQRERERQRDAEKERERQTDRERQRQT 171
Query: 793 DPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREF 852
+ R + + N+ +E+ ERE +K+ + EDR + R ER + E +
Sbjct: 172 ERNRQKEREREKNR----QERRERERQREKENKTEDRHSERGRERERERETETETERKRQ 227
Query: 853 RSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSK 907
+R+ + RE K A + +RE K+++ E+ +
Sbjct: 228 TDRERDRQRKTERER------------EKQAERERASERETERDKERERERDRDR 270
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 53.5 bits (127), Expect = 9e-07
Identities = 75/373 (20%), Positives = 152/373 (40%), Gaps = 39/373 (10%)
Query: 202 LKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALC 261
++E E RE E ++RR E + KE EK R + +E +M + +
Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEE--------KMRRQEEMMW 434
Query: 262 AEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGP 321
+ K R EE + + + EEK + + +I + + + +AK R+ + IR
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK-----MWRQEEKIREQ 489
Query: 322 DGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLAC 381
+ K+ M + + +EK + E + + + E + E E ++
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE---EKIREQEEI-------- 538
Query: 382 TRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYR 441
R+ + I + K+ M + ++E+K +E + + RQ + EE E
Sbjct: 539 WRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Query: 442 KSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAK--REAAKEICSEF 499
+ + + + + + KM C E +QEE+ R + + RE K+I E
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKM----CEQEEKMQEQEEKMRRQEEKIREQEKKI-REQ 653
Query: 500 RDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVK 559
+++R + ++ + KM + MC K++E+E+K ++E+ E E
Sbjct: 654 EEKIRE-------QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 706
Query: 560 REAVQELCSEYRH 572
R+ +++ H
Sbjct: 707 RQQEEKMQEHQEH 719
Score = 41.6 bits (96), Expect = 0.003
Identities = 55/325 (16%), Positives = 135/325 (41%), Gaps = 49/325 (15%)
Query: 539 EEEEKKNDKEEKGKVEAEKVKRE------------AVQELCSEYRHYVRNGRLPCTREND 586
E+EEK ++EEK + + EK++R+ +E+ E +R + +
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438
Query: 587 PIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFC 646
I L+ K+H Q++ +E+E KR+ E++ ++ +R Q K++
Sbjct: 439 KIRELEEKMHE----------QEKIREQEE-------KRQEEEKIREQEKRQEQEAKMW- 480
Query: 647 TRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDE 706
R+ + +R + K + M + + +E+ R+EE+ Q Q+E
Sbjct: 481 -RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMW---------RQEE 530
Query: 707 CAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTG 766
+E++ + + + +R + K + + M + + + + + +
Sbjct: 531 KIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQ 590
Query: 767 SESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKED 826
E ++ ++ R Q + T+E + G + K +EK++ + + +++E+
Sbjct: 591 EEKIREQEEKIREQEE-----MTQEQEEKMGEQEE----KMCEQEEKMQEQEEKMRRQEE 641
Query: 827 EDRSNTGERSNTGERSNDKEDLCRE 851
+ R + E+ ++E++ +E
Sbjct: 642 KIREQEKKIREQEEKIREQEEMMQE 666
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 51.6 bits (122), Expect = 3e-06
Identities = 92/459 (20%), Positives = 190/459 (41%), Gaps = 50/459 (10%)
Query: 202 LKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPD------GRMHG 255
++E E RE E ++RR E + KE EK R + +E R + +M
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 381
Query: 256 NKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTREN 315
+ + + K R EE + + + EEK + + +I + + + +AK R+
Sbjct: 382 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK-----MWRQE 436
Query: 316 DPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVR 375
+ IR + K+ M + + +EK + E + + + E + E E ++ R
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE---EKIHEQEEIWR 493
Query: 376 NGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKK--KKEGKSRNK----RQSKS 429
K + + I+ + KV + E + E+E+K ++E K R + R+ +
Sbjct: 494 Q-KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 430 TASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKR 489
E++ E ++ + +++ R+ + I+ + K+ + E +++E+ K+
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMW--RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 490 EAA----KEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKN 545
E +E E +++R + + + KM + MC K++E+E+
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670
Query: 546 DKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEA 605
++E+ E EK RE +++ + + ++ + K+ MCE
Sbjct: 671 WRQEEKIREQEKKIREQEEKI---------------REQEEMMQEQEEKMWEQEEKMCE- 714
Query: 606 FFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKL 644
QE K +E+ E K++R+ EK E R Q K+
Sbjct: 715 ---QEEKMQEQEE---KMRRQEEKMWEQEVRLRQQEEKM 747
Score = 44.3 bits (103), Expect = 5e-04
Identities = 62/335 (18%), Positives = 141/335 (42%), Gaps = 29/335 (8%)
Query: 539 EEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGN 598
E+EEK ++EEK + + EK++R+ +E+ E +R + + + + +
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 375
Query: 599 TCSMC---EAFFQQEAKEKERAEP--------RAKVKREAEKETCDEFRRLLQNGKLFCT 647
M E +++E K +E E + KR+ E++ ++ +R Q K++
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW-- 433
Query: 648 RENDPVRGPDGKTHGNKCAMCKA-----VFQKENEERKRKEEEDQRNAAGHGSSGGGGGN 702
R+ + +R + K + M + +K EE KR+E+E+
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493
Query: 703 TQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRS 762
+++ E E+++ R+ + +R+ + K + K+ R+ E+ E
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE-----EKMWRQEEKIREQEEMWR 548
Query: 763 NGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKK 822
+ +E + Q + K+ R+ + +R + K + + +++ +R+ E+K
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKM--WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 823 --KKEDEDRSNTGERSNTGERSNDKEDLCREFRSM 855
K+E++ R + E+ ++E+ RE M
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641
Score = 32.0 bits (71), Expect = 2.7
Identities = 46/256 (17%), Positives = 99/256 (38%), Gaps = 20/256 (7%)
Query: 202 LKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDG------RMHG 255
+ E E R+ E ++ R EK +E E+++R R+ + +R + +MH
Sbjct: 498 MHEQEEKIRKQEEKVWRQEEK--IREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Query: 256 NKCALCAEIFKQRFSEENSKTDQNLGKAEEKT-----KVKREIVKLCSQYQNQAKNGILF 310
+ + E +Q ++ + ++ + + EEK K++ + K Q + K
Sbjct: 556 QE-KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 311 CTREN------DPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYA 364
+E + IR + K+ + + +E+K E + + +
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
Query: 365 ELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNK 424
E E K +R + + + +Q + K+ MCE + +E+E+K + + +
Sbjct: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
Query: 425 RQSKSTASFEELCSEY 440
Q EE E+
Sbjct: 735 EQEVRLRQQEEKMQEH 750
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 50.8 bits (120), Expect = 6e-06
Identities = 65/308 (21%), Positives = 127/308 (41%), Gaps = 41/308 (13%)
Query: 340 ENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNT 399
+ E+K E + + + K E+ E + +R + + + I+ + K+H
Sbjct: 298 QEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ- 356
Query: 400 CSMCEVFFQAEE---EEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTREND 456
E + EE EE+K +E + R ++++K E++ + K R+ + +
Sbjct: 357 ----EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE--------QEE 404
Query: 457 PIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNP 516
+Q + KM M E Q+EE + K +E E ++R +
Sbjct: 405 MMQEQEEKMGEQEEKMWE---QEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461
Query: 517 VRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRN 576
++ + KM + MC K++E+E+K ++E+ E EK RE +++
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI---------- 511
Query: 577 GRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFR 636
+ + ++ + K+ MCE QE K +E+ E K++R+ EK E R
Sbjct: 512 -----REQEEMMQEQEEKMWEQEEKMCE----QEEKMQEQEE---KMRRQEEKMREQEVR 559
Query: 637 RLLQNGKL 644
Q K+
Sbjct: 560 LRQQEEKM 567
Score = 50.4 bits (119), Expect = 7e-06
Identities = 56/286 (19%), Positives = 116/286 (40%), Gaps = 24/286 (8%)
Query: 213 ETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEE 272
E +I+ EK +E E+++R R+ + + + +M + + + K R EE
Sbjct: 294 EEKIQEREEK--IQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 351
Query: 273 NSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSM 332
+ + + EEK + + +I + + + +AK R+ + IR + K+ M
Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK-----MWRQEEKIREQEEKIREQEEMM 406
Query: 333 CQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPD 392
+ + +E+K E + + K E E K +R + + + +Q +
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 466
Query: 393 GKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCT 452
K+ MCE + +E+E+K + + + + Q K EE E
Sbjct: 467 EKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE------------- 513
Query: 453 RENDPIQGPDGKMHGNTCSMC---EAFFQQEERARAKAKREAAKEI 495
+ + +Q + KM MC E +QEE+ R + ++ +E+
Sbjct: 514 -QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV 558
Score = 40.8 bits (94), Expect = 0.006
Identities = 49/219 (22%), Positives = 97/219 (44%), Gaps = 19/219 (8%)
Query: 478 QQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFK 537
Q+E+ R + K + +E E +++R R+ + + KM + M K
Sbjct: 286 QEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 345
Query: 538 LEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHG 597
+ E E+K ++E K+ ++ KR+ +++ + + + ++ R+ + I + KI
Sbjct: 346 IRELEEKMHEQE--KIREQEEKRQEEEKIREQEKRQEQEAKM--WRQEEKIREQEEKIRE 401
Query: 598 NTCSMC---EAFFQQEAK----EKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTREN 650
M E +QE K E+E E K++R+ EK E + Q K+ RE
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI---REQ 458
Query: 651 DPVRGPD----GKTHGNKCAMCKAVFQKENEERKRKEEE 685
+ + G+ G C +A Q++ E+ +R+EE+
Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQ-EAKMQEQEEKMRRQEEK 496
Score = 38.9 bits (89), Expect = 0.022
Identities = 54/269 (20%), Positives = 104/269 (38%), Gaps = 32/269 (11%)
Query: 202 LKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALC 261
++E E RE E ++RR E + KE EK R + +E + +R + +MH +
Sbjct: 304 IQEQEEKIREQEEKMRRQEEMMWEKE-EKMRRQEEMMWEKE-EKIRELEEKMHEQEKIRE 361
Query: 262 AEIFKQ-----RFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGI-------- 308
E +Q R E+ + + + + EEK + + E ++ + + + +
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421
Query: 309 ----------LFCTRENDPIRGPDGKMHGNLCSMC-QAYFQAENEEK------KKAEARA 351
R+ + IR + K+ + Q E EEK K E A
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481
Query: 352 RNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEE 411
+ + + K E E K +R + + + +Q + K+ MCE + +E
Sbjct: 482 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Query: 412 EEKKKKEGKSRNKRQSKSTASFEELCSEY 440
+E+K + + + + Q EE E+
Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 31.6 bits (70), Expect = 3.5
Identities = 51/298 (17%), Positives = 110/298 (36%), Gaps = 49/298 (16%)
Query: 608 QQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAM 667
Q EA + K +A+ E + + RL Q + R+ + ++ + K
Sbjct: 252 QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKI------- 304
Query: 668 CKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDP 727
+E EE+ R++EE R ++ E E+M+ + +
Sbjct: 305 ------QEQEEKIREQEEKMRRQ-------------EEMMWEKEEKMRRQEEMMWEKEEK 345
Query: 728 VRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLI 787
+R+ + K + + K+ + E++ E + R ++ + Q + K+
Sbjct: 346 IRELEEKMHEQE------KIREQEEKRQEEEKIR-------------EQEKRQEQEAKM- 385
Query: 788 CTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERS--NTGERSNDK 845
R+ + +R + K + M +++ + E+K E E+ E E+ ++
Sbjct: 386 -WRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444
Query: 846 EDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEK 903
E RE R + + + + GKM + M + E K +++EK
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK 502
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 50.8 bits (120), Expect = 6e-06
Identities = 80/392 (20%), Positives = 157/392 (40%), Gaps = 56/392 (14%)
Query: 410 EEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNT 469
E++ +K++E K+ KR S + S ++ R+ T N P + D
Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRRED------- 71
Query: 470 CSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKC 529
SM + + + A ++ + KE +D+ R R H GK H
Sbjct: 72 -SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK----RRHRSHSAEGGK-HA--- 122
Query: 530 AMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIE 589
+++E+E+++++ ++ + E +K +RE ++ E R RE D +E
Sbjct: 123 -------RVKEKEREHERRKRHREEQDKARREWERQKRREM------AREHSRRERDRLE 169
Query: 590 GLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQ--NGKLFCT 647
L+ K + Q+E KE+ER + +REA +E R + + + K+ +
Sbjct: 170 QLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKAS 229
Query: 648 R-ENDPVRGP-------DGKTHGNKCAMCKAVFQKENEER------KRKEEEDQRNAAGH 693
P R P DG+ K V +++ EER + + +++ ++
Sbjct: 230 HWSRSPPRPPRERFELGDGR---------KPVKEEKMEERDLLSDLQDISDSERKTSSAE 280
Query: 694 GSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAER 753
SS G +++E E E+ + G S + ES+ + + + + + E+ AE
Sbjct: 281 SSSAESGSGSEEEEEEEEEEEEEG--STSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 338
Query: 754 KNEYSRSRSNGTGSESGKDTCDEFRSQMKNGK 785
+E S +E+ E R +G+
Sbjct: 339 VSEEEMSEDEERENENHLLVVPESRFDRDSGE 370
Score = 45.8 bits (107), Expect = 2e-04
Identities = 78/416 (18%), Positives = 150/416 (36%), Gaps = 86/416 (20%)
Query: 538 LEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDG---- 593
L+E++++ ++EEK +++ K + + S +R+ R+ T N P D
Sbjct: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
Query: 594 -------------------KIHG-----------NTCSMCEAFFQQEAKEKERAEPRAKV 623
K+H + E KEKER R K
Sbjct: 77 GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKR 136
Query: 624 KREAEKETCDEFRRLLQN--GKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKR 681
RE + + E+ R + + RE D + + K + + Q+E +ER+R
Sbjct: 137 HREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERER 196
Query: 682 KEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRD---ADGKSYNN 738
+ EE ++ +++ Y +++K S + P DG+
Sbjct: 197 RAEERRKEREARREVSAHHRTMRED---YSDKVKASHWSRSPPRPPRERFELGDGRKPVK 253
Query: 739 QCTMCKAKLEREAERKNEYSRSRSNGTGS--ESGKDTCDEFRSQMKNGKLICTRESDPVR 796
+ M + L + + ++ R S+ S ESG + +E E +
Sbjct: 254 EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE-------------EEEEEEE 300
Query: 797 GPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQ 856
+G T E+ E E E++++E+E SN+ E S +E++ +
Sbjct: 301 EEEGST--------SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 352
Query: 857 RNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNA 912
N L+ + +S FDR++ E ++ +EE P ++A
Sbjct: 353 ENHLLV---------------------VPESRFDRDSGESEEAEEEVGEGTPQSSA 387
>gi|68299793 serine protease inhibitor, Kazal type 6 [Homo sapiens]
Length = 80
Score = 50.8 bits (120), Expect = 6e-06
Identities = 22/40 (55%), Positives = 30/40 (75%), Gaps = 4/40 (10%)
Query: 632 CDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAV 671
C EF Q+ K++CTRE++P G DG+T+GNKCA CKA+
Sbjct: 30 CGEF----QDPKVYCTRESNPHCGSDGQTYGNKCAFCKAI 65
Score = 49.3 bits (116), Expect = 2e-05
Identities = 23/48 (47%), Positives = 30/48 (62%), Gaps = 4/48 (8%)
Query: 764 GTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCK 811
G S+ G+ C EF+ K+ CTRES+P G DG+T+GNKC CK
Sbjct: 20 GVFSQGGQVDCGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCK 63
Score = 45.8 bits (107), Expect = 2e-04
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Query: 94 ELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGEC 151
+++C +F+ D C CG+DG+TY N+CA C K+G +I +K G+C
Sbjct: 27 QVDCGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
Score = 45.1 bits (105), Expect = 3e-04
Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Query: 496 CSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFK 537
C EF+D + CTRE NP G DG+ +GNKCA C ++ K
Sbjct: 30 CGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCKAIVK 67
Score = 43.5 bits (101), Expect = 0.001
Identities = 17/36 (47%), Positives = 26/36 (72%)
Query: 231 QVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFK 266
+ ++ +++CTRES+P G DG+ +GNKCA C I K
Sbjct: 32 EFQDPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVK 67
Score = 42.4 bits (98), Expect = 0.002
Identities = 16/29 (55%), Positives = 23/29 (79%)
Query: 169 RDGRLGCTRENDPVLGPDGKTHGNKCAMC 197
+D ++ CTRE++P G DG+T+GNKCA C
Sbjct: 34 QDPKVYCTRESNPHCGSDGQTYGNKCAFC 62
Score = 40.8 bits (94), Expect = 0.006
Identities = 17/42 (40%), Positives = 28/42 (66%), Gaps = 4/42 (9%)
Query: 704 QDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKA 745
Q +C E+++ ++ CTRES+P +DG++Y N+C CKA
Sbjct: 27 QVDCGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCKA 64
Score = 39.7 bits (91), Expect = 0.013
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 367 CSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK 420
C E++ + K+ CTRE++P G DG+ +GN C+ C+ ++ + K GK
Sbjct: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGK 79
Score = 38.9 bits (89), Expect = 0.022
Identities = 15/39 (38%), Positives = 27/39 (69%), Gaps = 4/39 (10%)
Query: 437 CSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEA 475
C E++ + +++CTRE++P G DG+ +GN C+ C+A
Sbjct: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKA 64
Score = 38.1 bits (87), Expect = 0.038
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 1 MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI 60
MK++ + +LL LAL Q C EFQ + K++C ++ DG +
Sbjct: 1 MKLSGMFLLLSLALFCFLTGVFSQGGQVDCGEFQ----DPKVYCTRESNPHCGSDGQTYG 56
Query: 61 NKCATCKMILEKEAK 75
NKCA CK I++ K
Sbjct: 57 NKCAFCKAIVKSGGK 71
Score = 38.1 bits (87), Expect = 0.038
Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 4/51 (7%)
Query: 838 TGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSI 888
TG S + C EF+ + K+ CTRE+NP G G+ + NKCA C++I
Sbjct: 19 TGVFSQGGQVDCGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAI 65
Score = 38.1 bits (87), Expect = 0.038
Identities = 15/39 (38%), Positives = 26/39 (66%), Gaps = 4/39 (10%)
Query: 297 CSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQA 335
C ++Q+ ++CTRE++P G DG+ +GN C+ C+A
Sbjct: 30 CGEFQDPK----VYCTRESNPHCGSDGQTYGNKCAFCKA 64
Score = 37.0 bits (84), Expect = 0.084
Identities = 16/46 (34%), Positives = 28/46 (60%), Gaps = 4/46 (8%)
Query: 567 CSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAK 612
C E++ + ++ CTRE++P G DG+ +GN C+ C+A + K
Sbjct: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGK 71
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 50.4 bits (119), Expect = 7e-06
Identities = 71/376 (18%), Positives = 151/376 (40%), Gaps = 40/376 (10%)
Query: 202 LKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALC 261
++E E RE E ++RR E + KE EK R + +E +M + +
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEE--------KMRRLEEMMW 373
Query: 262 AEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGP 321
+ K R EE + + + EEK + + +I + + + +AK R+ + IR
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK-----MWRQEEKIREQ 428
Query: 322 DGKMHGNLCSMCQAYFQAENEEKKKAEARARNK----RESGKATSYAELCSEYRKLVRNG 377
+ K+ M + + +EK + E + + + R+ K E+ + K+
Sbjct: 429 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQE 488
Query: 378 KLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELC 437
K+ ++ + + + K+H ++E+K +E + + RQ + EE
Sbjct: 489 KIR--KQEEKVWRQEEKMH--------------DQEEKIREQEEKMWRQEEKIREQEEKI 532
Query: 438 SEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKR-EAAKEIC 496
E + + + + + + KM E +QEE+ R + ++ KE
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-----EKMRRQEEKIREQEEKIREQKEKI 587
Query: 497 SEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAE 556
E +++ + ++ + KM + MC K++E+E+K ++E+ E E
Sbjct: 588 REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 647
Query: 557 KVKREAVQELCSEYRH 572
R+ +++ H
Sbjct: 648 VRLRQQEEKMQEHQEH 663
Score = 43.1 bits (100), Expect = 0.001
Identities = 64/312 (20%), Positives = 129/312 (41%), Gaps = 42/312 (13%)
Query: 340 ENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNT 399
E EEK + + R + E K ++ + ++ + K+ R+ + I+ + K+
Sbjct: 381 ELEEKMHEQEKIREQEE--KRQEEEKIREQEKRQEQEAKM--WRQEEKIREQEEKIREQE 436
Query: 400 CSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQ 459
M + E+EK ++E KRQ + EE+ + K R+ ++ +E
Sbjct: 437 KKMWRQEEKIHEQEKIREE----EKRQEQ-----EEMWRQEEKIREQEEIWRQKE----- 482
Query: 460 GPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRG 519
KMH +QE+ + + K +E + +++R R+ +R
Sbjct: 483 ----KMH-----------EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
Query: 520 PDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRL 579
+ K+ + + ++E+E+K ++E+ E EK++R+ +E E +R +
Sbjct: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ--EEKIREQEEKIREQKE 585
Query: 580 PCTRENDPIEGLDGKIHGNTCSMC---EAFFQQEAK----EKERAEPRAKVKREAEKETC 632
+ + I + KI M E ++QE K E++ E K++R+ EK
Sbjct: 586 KIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 645
Query: 633 DEFRRLLQNGKL 644
E R Q K+
Sbjct: 646 QEVRLRQQEEKM 657
Score = 40.8 bits (94), Expect = 0.006
Identities = 59/326 (18%), Positives = 140/326 (42%), Gaps = 21/326 (6%)
Query: 539 EEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGN 598
E+EEK ++EEK + + EK++R+ +E+ E +R + + + L+ +
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEK 375
Query: 599 TCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDG 658
+ E + +EK R + + KR+ E++ ++ +R Q K++ R+ + +R +
Sbjct: 376 EEKIRELEEKMHEQEKIREQ---EEKRQEEEKIREQEKRQEQEAKMW--RQEEKIREQEE 430
Query: 659 KTHGNKCAMCKA-----VFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQ 713
K + M + +K EE KR+E+E+ +++ E +E+
Sbjct: 431 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE-QEK 489
Query: 714 MKNGRLSCTRESDPVRDADGKSYNNQCTMCKAK---LEREAERKNEYSRSRSNGTGSESG 770
++ R+ + + D + K + M + + E+E + + + + R +
Sbjct: 490 IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ 549
Query: 771 KDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRS 830
++ E +M+ + + R+ + +R + K K + +++ + E+K +E E+
Sbjct: 550 EEKMGEQEEKMQEQEKM-RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMM 608
Query: 831 NTGERSNTGERSNDKEDLCREFRSMQ 856
E + +E +C + MQ
Sbjct: 609 QEQEE----KMWEQEEKMCEQEEKMQ 630
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 50.1 bits (118), Expect = 1e-05
Identities = 48/167 (28%), Positives = 75/167 (44%), Gaps = 21/167 (12%)
Query: 675 ENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYR-EQMKNGRLS---CTRESDPVRD 730
+NEE +KE+E+ +N G G +DE E ++ KNG + D +
Sbjct: 124 KNEEEDQKEDEEDQNE----EKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKG 179
Query: 731 ADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTR 790
DGK N + K + E+E E + E + N G E G K GK + +
Sbjct: 180 EDGKG-NGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKG---------DKKEGKDVKVK 229
Query: 791 ESDPVRGPDGKTH--GNKCTMCKEKLEREAAEKKKKEDEDRSNTGER 835
E + R DGK GN+ KEK + + E+ K+EDE + + G++
Sbjct: 230 EDEKER-EDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275
Score = 46.2 bits (108), Expect = 1e-04
Identities = 74/301 (24%), Positives = 116/301 (38%), Gaps = 65/301 (21%)
Query: 452 TRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICT 511
T E P + + M E +A A+ K+EA E ++ + +NG T
Sbjct: 31 TPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVE--EDYNENAKNGEAKIT 88
Query: 512 R----EHNPVRGPDGKMH------GNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKRE 561
E V + + G K A+ K EEE++K D+E++ + + E K E
Sbjct: 89 EAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGK-E 147
Query: 562 AVQELCSEYRHYVRNGR---LPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAE 618
E E +NG + D +G DGK +G ++ KEK E
Sbjct: 148 DKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNG-----------EDGKEKGEDE 196
Query: 619 PRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEE 678
+ E KET D +EN+ DGK G+K KE ++
Sbjct: 197 K----EEEDRKETGD-------------GKENE-----DGKEKGDK---------KEGKD 225
Query: 679 RKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNN 738
K KE+E +R G GG ++E + +E +K +E D +++ DGK
Sbjct: 226 VKVKEDEKERE---DGKEDEGG--NEEEAGKEKEDLKEEEEG--KEEDEIKEDDGKKEEP 278
Query: 739 Q 739
Q
Sbjct: 279 Q 279
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/206 (22%), Positives = 79/206 (38%), Gaps = 21/206 (10%)
Query: 673 QKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAE--YREQMKNGRLSCTR------- 723
++ + RK K + D S+ Q+ E Y E KNG T
Sbjct: 37 KRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKE 96
Query: 724 ----ESDPVRDADGKS-YNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTC-DEF 777
+ + + DA K + + K E E ++++E ++ G + KD +E
Sbjct: 97 IVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEED 156
Query: 778 RSQMKNGKLI---CTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGE 834
+ KNG + D +G DGK +G KEK E E E+ +KE D +
Sbjct: 157 GKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDG---KEKGEDEKEEEDRKETGDGKENED 213
Query: 835 RSNTGERSNDKEDLCREFRSMQRNGK 860
G++ K+ +E + +GK
Sbjct: 214 GKEKGDKKEGKDVKVKEDEKEREDGK 239
Score = 32.7 bits (73), Expect = 1.6
Identities = 40/161 (24%), Positives = 63/161 (39%), Gaps = 32/161 (19%)
Query: 410 EEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGR---LFCTRENDPIQGPDGKMH 466
EEE++K+ E ++ +E E K KNG + D +G DGK +
Sbjct: 126 EEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGN 185
Query: 467 GNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHG 526
G E + K + E +E E D N DGK G
Sbjct: 186 G-------------EDGKEKGEDEKEEEDRKETGDGKEN--------------EDGKEKG 218
Query: 527 NKCAMCASVFKLEEEEKKNDKEEKG--KVEAEKVKREAVQE 565
+K K +E+E+++ KE++G + EA K K + +E
Sbjct: 219 DKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEE 259
>gi|45505132 serine protease inhibitor, Kazal type 1 precursor [Homo
sapiens]
Length = 79
Score = 50.1 bits (118), Expect = 1e-05
Identities = 20/41 (48%), Positives = 24/41 (58%)
Query: 111 CPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGEC 151
C Y+ VCGTDG TY N C LC EN K + I ++ G C
Sbjct: 39 CTKIYDPVCGTDGNTYPNECVLCFENRKRQTSILIQKSGPC 79
Score = 38.1 bits (87), Expect = 0.038
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 7/46 (15%)
Query: 174 GCTRENDPVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRN 219
GCT+ DPV G DG T+ N+C +C EN KR+ I+++
Sbjct: 38 GCTKIYDPVCGTDGNTYPNECVLC-------FENRKRQTSILIQKS 76
Score = 36.6 bits (83), Expect = 0.11
Identities = 14/32 (43%), Positives = 21/32 (65%)
Query: 788 CTRESDPVRGPDGKTHGNKCTMCKEKLEREAA 819
CT+ DPV G DG T+ N+C +C E +R+ +
Sbjct: 39 CTKIYDPVCGTDGNTYPNECVLCFENRKRQTS 70
Score = 34.3 bits (77), Expect = 0.55
Identities = 16/50 (32%), Positives = 24/50 (48%)
Query: 701 GNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLERE 750
GNT + + N CT+ DPV DG +Y N+C +C +R+
Sbjct: 19 GNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQ 68
Score = 33.9 bits (76), Expect = 0.71
Identities = 15/32 (46%), Positives = 20/32 (62%)
Query: 239 CTRESDPVRGPDGRMHGNKCALCAEIFKQRFS 270
CT+ DPV G DG + N+C LC E K++ S
Sbjct: 39 CTKIYDPVCGTDGNTYPNECVLCFENRKRQTS 70
Score = 33.1 bits (74), Expect = 1.2
Identities = 12/23 (52%), Positives = 16/23 (69%)
Query: 646 CTRENDPVRGPDGKTHGNKCAMC 668
CT+ DPV G DG T+ N+C +C
Sbjct: 39 CTKIYDPVCGTDGNTYPNECVLC 61
Score = 30.4 bits (67), Expect = 7.9
Identities = 10/23 (43%), Positives = 16/23 (69%)
Query: 510 CTREHNPVRGPDGKMHGNKCAMC 532
CT+ ++PV G DG + N+C +C
Sbjct: 39 CTKIYDPVCGTDGNTYPNECVLC 61
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 49.3 bits (116), Expect = 2e-05
Identities = 98/510 (19%), Positives = 205/510 (40%), Gaps = 42/510 (8%)
Query: 206 ENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIF 265
E RE E +IR+ EK + +E + + G++ + + +R + R+ + L +
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKM--REQEEKMRRQEKRLREQEKELREQEK 297
Query: 266 KQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKM 325
+ R ++ + ++ + + EEK + E K+ Q + + +E +R + KM
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEE--KMREQEEKMWRQEERLWEQEKQ-MREQEQKM 354
Query: 326 HGNLCSMCQAYFQAENEEKKKAEARARNKR-ESGKATSYAELCSEYRKLVRNGKLACTRE 384
M + Q E +K+ R + K E + E E K +R + +
Sbjct: 355 RDQEERMWE---QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQ 411
Query: 385 NDPIQGPDGKVHGNTCSMCEVFFQAEE---------EEKKKKEGKSRNKRQSKSTASFEE 435
+ +Q K N E +Q + E++K +E + + Q + EE
Sbjct: 412 EEKMQ----KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 467
Query: 436 LCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMC---EAFFQQEERARAKAKREAA 492
+ + +K + ++ + D + + KM M E ++Q+ER R K +R
Sbjct: 468 MWGQEKKMWRQEKM--REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMRE 525
Query: 493 KEICSEFRDQVRNGTLICTRE------HNPVRGPDGKMHGNKCAMCASVFKLEEEEKKND 546
++ + +++R +E +R + K E+EEK +
Sbjct: 526 QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 585
Query: 547 KEEKGKVEAEKV--KREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCE 604
+EEK + + EK+ + E +QE E + + + ++ E D ++ + + M E
Sbjct: 586 QEEKMREQEEKMWEQEEKMQE--QEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQE 643
Query: 605 A---FFQQEAKEKERAEP--RAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGK 659
++QE K +E+ E + K + ++E E +Q + + + +RG + K
Sbjct: 644 QEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEK 703
Query: 660 THGNKCAMCKAVFQKENEERKRKEEEDQRN 689
G + M + +E R++EE R+
Sbjct: 704 MWGQEEKMWGQEEKMWGQEEMREKEERIRD 733
Score = 46.2 bits (108), Expect = 1e-04
Identities = 102/559 (18%), Positives = 218/559 (38%), Gaps = 92/559 (16%)
Query: 341 NEEKKKAEARARNK---RESGKATSYAELCSEYRKLVRNGKLA-----------CTREND 386
NEE KK A + K ES K+ + RKL R L R+ +
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 387 PIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFE-ELCSEYRKSRK 445
++ + K+ M + E+E K +E + + +RQ K E EL + ++ R+
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 446 NGRLFCTRENDPIQGPDGKMHGNTCSMC-------------------------------E 474
+L + + +Q + KM M E
Sbjct: 302 QKKL--REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 475 AFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCAS 534
++Q+ER R K +R +E E ++++ I RE +R + M + M
Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE-KKMREEEETMREQEEKMQKQ 418
Query: 535 VFKLEEEEKKNDKEEKGKVEAEKV-KREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDG 593
+ E+E+K ++++ + EK+ ++E +QE E + + + ++ R+ + + G +
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE--QEEKIWEQEEKI---RDQEEMWGQEK 473
Query: 594 KI--HGNTCSMCEAFFQQEAK----------EKERAEPRAKVKREAEKETCDEFRRLLQN 641
K+ + ++QE K ++ER + + RE E+ ++ + Q
Sbjct: 474 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE 533
Query: 642 GKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGG 701
K+ RE + + KT + M + +E E++ R+EEE R
Sbjct: 534 EKM---REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR------------- 577
Query: 702 NTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSR 761
+++ E E+M+ + + +++ + K + + M + + E + + + E +
Sbjct: 578 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ 637
Query: 762 SNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEK 821
++ E +M + + + +R + K G + M +++ + + E+
Sbjct: 638 ---------EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
Query: 822 KKKEDEDRSNTGERSNTGE 840
K +E E++ E G+
Sbjct: 689 KMREQEEKMRGQEEKMWGQ 707
Score = 45.1 bits (105), Expect = 3e-04
Identities = 75/392 (19%), Positives = 153/392 (39%), Gaps = 29/392 (7%)
Query: 204 EAENAKREGETRIRRNA---EKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCAL 260
E + RE E R+R E++ + E+++R E + +R + +M + +
Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422
Query: 261 CAEIFK----QRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILF----CT 312
+ K QR E+ K + E++ K+ + K+ Q + + ++
Sbjct: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 482
Query: 313 RENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRK 372
+ D + + KM M + ++++ E R RE K E E +K
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER-MREQKKMWQQEEKMREEKK 541
Query: 373 LVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTAS 432
K +E + + ++ M E E+E+K +E + + + Q +
Sbjct: 542 TQEQEKKTWDQEEKMRE--EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599
Query: 433 FEELCSEYRKS--RKNGRLFCTRENDPIQGPDGKMHGNTCSMCEA---FFQQEERARAKA 487
EE E + + +++ E D +Q + M M E ++QEE+ R +
Sbjct: 600 QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659
Query: 488 --------KREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLE 539
K + +E E ++++ + +RG + KM G + M K+
Sbjct: 660 EKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMW 719
Query: 540 EEEKKNDKEEKGKVEAEKVKREAV--QELCSE 569
+E+ +KEE+ + + EK++ +E CSE
Sbjct: 720 GQEEMREKEERIRDQKEKMQERLPEHEERCSE 751
Score = 44.7 bits (104), Expect = 4e-04
Identities = 82/448 (18%), Positives = 172/448 (38%), Gaps = 47/448 (10%)
Query: 204 EAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAE 263
E E RE E ++ R E+ + E EKQ+R + + + D R+ K E
Sbjct: 321 EQEEKMREQEEKMWRQEERLW--EQEKQMREQEQKMRDQEERMWEQDERLR-EKEERMRE 377
Query: 264 IFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQ-YQNQAKNGILFCTRENDPIRGPD 322
K EE + ++ + + E+K + + E ++ + Q Q +N +E R P+
Sbjct: 378 QEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 437
Query: 323 GKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACT 382
K + E++K E + + K E+ + +K+ R K+
Sbjct: 438 QK-------------EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR-- 482
Query: 383 RENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRK 442
+ D + + K+ M + + E++++ +E + R + Q K E++ E +
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Query: 443 SRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQ 502
+ + + E ++EER R + K+ +E +
Sbjct: 543 QEQEKKTWDQEEK---------------------MREEERMREREKKMREEE------EM 575
Query: 503 VRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKL-EEEEKKNDKEEKGKVEAEKVKRE 561
+R + +R + KM + M K+ E+EEK ++EE+ K++ ++
Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMW 635
Query: 562 AVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRA 621
+E E + + + + + K+ G M E + + +E++ E
Sbjct: 636 EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695
Query: 622 KVKREAEKETCDEFRRLLQNGKLFCTRE 649
K++ + EK E + Q K++ E
Sbjct: 696 KMRGQEEKMWGQEEKMWGQEEKMWGQEE 723
Score = 39.7 bits (91), Expect = 0.013
Identities = 88/439 (20%), Positives = 172/439 (39%), Gaps = 54/439 (12%)
Query: 469 TCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNK 528
T ++ E ++QEE R + K+ +R R+ +R +GKM +
Sbjct: 229 TNTLQEEMWRQEEELREQEKK-------------IRKQEEKMWRQEERLREQEGKMREQE 275
Query: 529 CAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPI 588
M +L E+EK+ ++EK E +K++ + Q E + + + ++ RE +
Sbjct: 276 EKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKM---REQE-- 330
Query: 589 EGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTR 648
E ++QE ER + K RE E++ D+ R+ + + R
Sbjct: 331 ---------------EKMWRQE----ERLWEQEKQMREQEQKMRDQEERMWEQDERL--R 369
Query: 649 ENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECA 708
E + K + M + +E E++ R+EEE R Q+E
Sbjct: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE-K 428
Query: 709 EYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERK---NEYSRSRSNGT 765
E+++Q + E + +++ + K + + + + E+K E R + +
Sbjct: 429 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 488
Query: 766 GSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKE 825
+ K E +M + + + + +R + + K +E+ RE EKK +E
Sbjct: 489 WEQEEKMRDQE--QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE--EKKTQE 544
Query: 826 DEDRS-NTGERSNTGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAM 884
E ++ + E+ ER ++E RE M R + + +R KM + M
Sbjct: 545 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM 604
Query: 885 CQSIFDREANERKKKDEEK 903
+E E+ + EEK
Sbjct: 605 ------QEQEEKMWEQEEK 617
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 48.1 bits (113), Expect = 4e-05
Identities = 111/542 (20%), Positives = 206/542 (38%), Gaps = 56/542 (10%)
Query: 341 NEEKKKAEARARNK---RESGKATSYAELCSEYRKLVRNGKLA-----------CTREND 386
NEE KK A + K ES K+ + RKL R L R+ +
Sbjct: 220 NEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 279
Query: 387 PIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKN 446
++ + K+ M + E+E K +E + + RQ K E+ E K +
Sbjct: 280 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE 339
Query: 447 GRLFCTRENDPIQGPDGKMHGNTCSMCEA---FFQQEERARAKAKREAAKEICSEFRDQV 503
+ +E + +Q + KM M E ++QEER + K+ +E + RDQ
Sbjct: 340 QKELREQE-EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE--QKMRDQE 396
Query: 504 RNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAV 563
+ +R + +M + M V K+ EE+K ++E+K + + EK++ E
Sbjct: 397 ER----MWEQDERLREKEERMREQE-KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE-- 449
Query: 564 QELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKV 623
+R E + + + K+ +M E Q+E + +++ P K
Sbjct: 450 --------ERIREREKKMREEEETMREQEEKMQKQEENMWE---QEEKEWQQQRLPEQKE 498
Query: 624 KR-EAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRK 682
K E EK E + Q K+ R+ + + G + K + + E EE+ R
Sbjct: 499 KLWEQEKMQEQEEKIWEQEEKI---RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD 555
Query: 683 EEE---DQRNAAGHGSSGGGGGN-TQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNN 738
+E+ DQ + Q+E E+M+ E + +R+ + K
Sbjct: 556 QEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 615
Query: 739 QCTMCKAKLEREAER--KNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVR 796
+ K++ + E+ + E E + ++ + +L + + +
Sbjct: 616 E-----EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL--PEQKEKLW 668
Query: 797 GPDGKTHGNKCTMCKEKL-EREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSM 855
+ K +EK+ E+E EKK +E E ++ E+ E ++E RE M
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728
Query: 856 QR 857
R
Sbjct: 729 MR 730
Score = 43.5 bits (101), Expect = 0.001
Identities = 95/499 (19%), Positives = 193/499 (38%), Gaps = 61/499 (12%)
Query: 177 RENDPVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGR 236
RE + + KT + M E ++E E RE E +R EK +KQ N
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK-----MQKQEENMW 481
Query: 237 LFCTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKL 296
+E R P+ + ++++Q E+ + ++ + + EEK + + E+
Sbjct: 482 EQEEKEWQQQRLPEQK---------EKLWEQ---EKMQEQEEKIWEQEEKIRDQEEMWGQ 529
Query: 297 CSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAEN---EEKKKAEARARN 353
+ Q K + D + + KM M + E E++KK +
Sbjct: 530 EKKMWRQEK-----MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEK 584
Query: 354 KRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEE 413
RE + + E +++R + + + +Q + K+ M E + E+E
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Query: 414 KKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMC 473
+K E + + Q + E+L E+ K ++ ++ +E + KM T
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLW-EHEKMQEQEKM---QEQEEKIWEQEKMEKKTQEQE 700
Query: 474 EAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCA 533
+ + QE+ ++ RE K++ E + +R + ++ + +M + M
Sbjct: 701 KKTWDQEKMREEESMREREKKMREE-EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE 759
Query: 534 SVFKL--------------------------EEEEKKNDKEEKGKVEAEKVKREAVQELC 567
K+ E+EEK D+EEK + + EK++ + +
Sbjct: 760 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRG 819
Query: 568 SEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREA 627
E + + + ++ + + + G + K+ G M E QE K +E+ E K++ +
Sbjct: 820 QEEKMWGQEEKM--WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEE---KMRGQE 874
Query: 628 EKETCDEFRRLLQNGKLFC 646
EK E + Q K++C
Sbjct: 875 EKMREQEEKMRGQEEKIYC 893
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 47.8 bits (112), Expect = 5e-05
Identities = 82/392 (20%), Positives = 154/392 (39%), Gaps = 58/392 (14%)
Query: 410 EEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNT 469
E++ +K++E K+ KR S + S ++ + T N P + D
Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRRED------- 71
Query: 470 CSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKC 529
SM + + + A ++ + KE +D+ R R H+ +G H
Sbjct: 72 -SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKC---RHHS--HSAEGGKH---- 121
Query: 530 AMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIE 589
A V + E E +K +EE+ K E +R+ +E+ E+ RE D +E
Sbjct: 122 ---ARVKEREHERRKRHREEQDKARREW-ERQKRREMAREHSR----------RERDRLE 167
Query: 590 GLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQ--NGKLFCT 647
L+ K + Q+E KE+ER + +REA +E R + + + K+ +
Sbjct: 168 QLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKAS 227
Query: 648 R-ENDPVRGP-------DGKTHGNKCAMCKAVFQKENEER------KRKEEEDQRNAAGH 693
P R P DG+ K V +++ EER + + +++ ++
Sbjct: 228 HWSRSPPRPPRERFELGDGR---------KPVKEEKMEERDLLSDLQDISDSERKTSSAE 278
Query: 694 GSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAER 753
SS G +++E E E+ + G S + ES+ + + + + + E+ AE
Sbjct: 279 SSSAESGSGSEEEEEEEEEEEEEG--STSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 336
Query: 754 KNEYSRSRSNGTGSESGKDTCDEFRSQMKNGK 785
+E S +E+ E R +G+
Sbjct: 337 VSEEEMSEDEERENENHLLVVPESRFDRDSGE 368
Score = 42.7 bits (99), Expect = 0.002
Identities = 61/311 (19%), Positives = 118/311 (37%), Gaps = 52/311 (16%)
Query: 609 QEAKEKERAEPRAKVKREAEKETCDEFRRLLQN--GKLFCTRENDPVRGPDGKTHGNKCA 666
+ A+ KER R K RE + + E+ R + + RE D + + K +
Sbjct: 120 KHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKM 179
Query: 667 MCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESD 726
+ Q+E +ER+R+ EE ++ +++ Y +++K S +
Sbjct: 180 REQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED---YSDKVKASHWSRSPPRP 236
Query: 727 PVRD---ADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGS--ESGKDTCDEFRSQM 781
P DG+ + M + L + + ++ R S+ S ESG + +E
Sbjct: 237 PRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE----- 291
Query: 782 KNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGER 841
E + +G T E+ E E E++++E+E SN+ E S
Sbjct: 292 --------EEEEEEEEEEGST--------SEESEEEEEEEEEEEEETGSNSEEASEQSAE 335
Query: 842 SNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDE 901
+E++ + N L+ + +S FDR++ E ++ +E
Sbjct: 336 EVSEEEMSEDEERENENHLLV---------------------VPESRFDRDSGESEEAEE 374
Query: 902 EKSSSKPSNNA 912
E P ++A
Sbjct: 375 EVGEGTPQSSA 385
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 47.8 bits (112), Expect = 5e-05
Identities = 44/188 (23%), Positives = 77/188 (40%), Gaps = 13/188 (6%)
Query: 673 QKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDAD 732
+K + ER+RKE+E RN T+ E RE+ K R + RD D
Sbjct: 96 RKRDRERRRKEKETNRNRDREKQ-------TEIERDREREKQKGRERERDRGRERERDRD 148
Query: 733 GKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRES 792
+ + T +RE E + E R R E+ +D R + ++ + R++
Sbjct: 149 REKERERQTEKDRDGQRETETERERDREREKQKERETERD-----RDRQRDTEKERERQT 203
Query: 793 DPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREF 852
D R KT + + ERE +++++ DR ER +R +++ ++
Sbjct: 204 DRERDRQRKTQTERQRETDREGERE-TDRRRERQRDRDRGKERDRERDRKEERKKERKKE 262
Query: 853 RSMQRNGK 860
R +R K
Sbjct: 263 RKKERKEK 270
Score = 46.2 bits (108), Expect = 1e-04
Identities = 51/234 (21%), Positives = 93/234 (39%), Gaps = 34/234 (14%)
Query: 608 QQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAM 667
++ KE++R R + +R EKET + R + ++ RE + +G + + +
Sbjct: 86 EKTEKERDRDRKRDRERRRKEKET-NRNRDREKQTEIERDREREKQKGRERERDRGRERE 144
Query: 668 CKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDP 727
+KE E + K+ + QR T+ E RE+ K R+ D
Sbjct: 145 RDRDREKERERQTEKDRDGQR-------------ETETERERDREREKQKERETERDRDR 191
Query: 728 VRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLI 787
RD E+E ER+ + R R T +E ++T E + +
Sbjct: 192 QRDT----------------EKERERQTDRERDRQRKTQTERQRETDREGERETDRRR-- 233
Query: 788 CTRESDPVRGPD-GKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGE 840
R+ D RG + + K KE+ + E+K+K+ E++ ++ GE
Sbjct: 234 -ERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
Score = 42.0 bits (97), Expect = 0.003
Identities = 51/233 (21%), Positives = 87/233 (37%), Gaps = 29/233 (12%)
Query: 679 RKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNN 738
R +E + G G + Q E RE+ + R + R + ++ N
Sbjct: 53 RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRN 112
Query: 739 QCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGP 798
+ + ++ER+ ER+ + R R G E +D RE + R
Sbjct: 113 RDREKQTEIERDREREKQKGRERERDRGRERERDR---------------DREKERERQT 157
Query: 799 DGKTHGNKCTMCKEKLEREAAEKKKKEDE-DRSNTGERSNTGERSNDKEDLCREFRSMQR 857
+ G + T + + +RE ++K++E E DR + ER D+E R QR
Sbjct: 158 EKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRE------RDRQR 211
Query: 858 NGKLICTRENNPVRGPYGKMHINKCAMCQSIFDR---EANERKKKDEEKSSSK 907
+ RE + G+ ++ Q DR ER +K+E K K
Sbjct: 212 KTQTERQRETD----REGERETDRRRERQRDRDRGKERDRERDRKEERKKERK 260
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 47.4 bits (111), Expect = 6e-05
Identities = 76/405 (18%), Positives = 148/405 (36%), Gaps = 75/405 (18%)
Query: 538 LEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDG---- 593
L+E++++ ++EEK +++ K + + S +R+ + T N P D
Sbjct: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
Query: 594 -------------------KIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDE 634
K+H + KEKER R K RE + + E
Sbjct: 77 GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARRE 136
Query: 635 FRRLLQN--GKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAG 692
+ R + + RE D + + K + + Q+E +ER+R+ EE ++
Sbjct: 137 WERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREA 196
Query: 693 HGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRD---ADGKSYNNQCTMCKAKLER 749
+++ Y +++K S + P DG+ + M + L
Sbjct: 197 RREVSAHHRTMRED---YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLS 253
Query: 750 EAERKNEYSRSRSNGTGS--ESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKC 807
+ + ++ R S+ S ESG + +E E + +G T
Sbjct: 254 DLQDISDSERKTSSAESSSAESGSGSEEE-------------EEEEEEEEEEGST----- 295
Query: 808 TMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLICTREN 867
E+ E E E++++E+E SN+ E S +E++ + N L+
Sbjct: 296 ---SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV----- 347
Query: 868 NPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNA 912
+ +S FDR++ E ++ +EE P ++A
Sbjct: 348 ----------------VPESRFDRDSGESEEAEEEVGEGTPQSSA 376
Score = 47.0 bits (110), Expect = 8e-05
Identities = 55/265 (20%), Positives = 113/265 (42%), Gaps = 33/265 (12%)
Query: 537 KLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIH 596
+++E+E+++++ ++ + E +K +RE ++ E R RE D +E L+ K
Sbjct: 112 RVKEKEREHERRKRHREEQDKARREWERQKRREM------AREHSRRERDRLEQLERKRE 165
Query: 597 GNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQ--NGKLFCTR-ENDPV 653
+ Q+E KE+ER + +REA +E R + + + K+ + P
Sbjct: 166 RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 225
Query: 654 RGP-------DGKTHGNKCAMCKAVFQKENEER------KRKEEEDQRNAAGHGSSGGGG 700
R P DG+ K V +++ EER + + +++ ++ SS G
Sbjct: 226 RPPRERFELGDGR---------KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 276
Query: 701 GNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRS 760
+++E E E+ + G S + ES+ + + + + + E+ AE +E S
Sbjct: 277 SGSEEEEEEEEEEEEEG--STSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 334
Query: 761 RSNGTGSESGKDTCDEFRSQMKNGK 785
+E+ E R +G+
Sbjct: 335 EDEERENENHLLVVPESRFDRDSGE 359
Score = 34.3 bits (77), Expect = 0.55
Identities = 36/234 (15%), Positives = 89/234 (38%), Gaps = 15/234 (6%)
Query: 537 KLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPI-EGLDGKI 595
+LE+ E+K ++E K + + ++ + + +E +E R R R + + + E K+
Sbjct: 156 RLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV 215
Query: 596 HGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRG 655
+ S +E E K ++ E++ + + + + + + E+
Sbjct: 216 KASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAES 275
Query: 656 PDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMK 715
G + ++E EE EE ++ G N+++ + E++
Sbjct: 276 GSGSEEEEE------EEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 329
Query: 716 NGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSES 769
+S D + ++ N+ + +++ +R++ E GT S
Sbjct: 330 EEEMS--------EDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 375
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 47.0 bits (110), Expect = 8e-05
Identities = 55/265 (20%), Positives = 113/265 (42%), Gaps = 33/265 (12%)
Query: 537 KLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIH 596
+++E+E+++++ ++ + E +K +RE ++ E R RE D +E L+ K
Sbjct: 89 RVKEKEREHERRKRHREEQDKARREWERQKRREM------AREHSRRERDRLEQLERKRE 142
Query: 597 GNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQ--NGKLFCTR-ENDPV 653
+ Q+E KE+ER + +REA +E R + + + K+ + P
Sbjct: 143 RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 202
Query: 654 RGP-------DGKTHGNKCAMCKAVFQKENEER------KRKEEEDQRNAAGHGSSGGGG 700
R P DG+ K V +++ EER + + +++ ++ SS G
Sbjct: 203 RPPRERFELGDGR---------KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 253
Query: 701 GNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRS 760
+++E E E+ + G S + ES+ + + + + + E+ AE +E S
Sbjct: 254 SGSEEEEEEEEEEEEEG--STSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 311
Query: 761 RSNGTGSESGKDTCDEFRSQMKNGK 785
+E+ E R +G+
Sbjct: 312 EDEERENENHLLVVPESRFDRDSGE 336
Score = 44.7 bits (104), Expect = 4e-04
Identities = 62/308 (20%), Positives = 117/308 (37%), Gaps = 52/308 (16%)
Query: 612 KEKERAEPRAKVKREAEKETCDEFRRLLQN--GKLFCTRENDPVRGPDGKTHGNKCAMCK 669
KEKER R K RE + + E+ R + + RE D + + K + +
Sbjct: 91 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQ 150
Query: 670 AVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVR 729
Q+E +ER+R+ EE ++ +++ Y +++K S + P
Sbjct: 151 QKEQREQKERERRAEERRKEREARREVSAHHRTMRED---YSDKVKASHWSRSPPRPPRE 207
Query: 730 D---ADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGS--ESGKDTCDEFRSQMKNG 784
DG+ + M + L + + ++ R S+ S ESG + +E
Sbjct: 208 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE-------- 259
Query: 785 KLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSND 844
E + +G T E+ E E E++++E+E SN+ E S
Sbjct: 260 -----EEEEEEEEEEGST--------SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 306
Query: 845 KEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKS 904
+E++ + N L+ + +S FDR++ E ++ +EE
Sbjct: 307 EEEMSEDEERENENHLLV---------------------VPESRFDRDSGESEEAEEEVG 345
Query: 905 SSKPSNNA 912
P ++A
Sbjct: 346 EGTPQSSA 353
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 47.0 bits (110), Expect = 8e-05
Identities = 55/265 (20%), Positives = 113/265 (42%), Gaps = 33/265 (12%)
Query: 537 KLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIH 596
+++E+E+++++ ++ + E +K +RE ++ E R RE D +E L+ K
Sbjct: 78 RVKEKEREHERRKRHREEQDKARREWERQKRREM------AREHSRRERDRLEQLERKRE 131
Query: 597 GNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQ--NGKLFCTR-ENDPV 653
+ Q+E KE+ER + +REA +E R + + + K+ + P
Sbjct: 132 RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 191
Query: 654 RGP-------DGKTHGNKCAMCKAVFQKENEER------KRKEEEDQRNAAGHGSSGGGG 700
R P DG+ K V +++ EER + + +++ ++ SS G
Sbjct: 192 RPPRERFELGDGR---------KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 242
Query: 701 GNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRS 760
+++E E E+ + G S + ES+ + + + + + E+ AE +E S
Sbjct: 243 SGSEEEEEEEEEEEEEG--STSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 300
Query: 761 RSNGTGSESGKDTCDEFRSQMKNGK 785
+E+ E R +G+
Sbjct: 301 EDEERENENHLLVVPESRFDRDSGE 325
Score = 44.7 bits (104), Expect = 4e-04
Identities = 62/308 (20%), Positives = 117/308 (37%), Gaps = 52/308 (16%)
Query: 612 KEKERAEPRAKVKREAEKETCDEFRRLLQN--GKLFCTRENDPVRGPDGKTHGNKCAMCK 669
KEKER R K RE + + E+ R + + RE D + + K + +
Sbjct: 80 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQ 139
Query: 670 AVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVR 729
Q+E +ER+R+ EE ++ +++ Y +++K S + P
Sbjct: 140 QKEQREQKERERRAEERRKEREARREVSAHHRTMRED---YSDKVKASHWSRSPPRPPRE 196
Query: 730 D---ADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGS--ESGKDTCDEFRSQMKNG 784
DG+ + M + L + + ++ R S+ S ESG + +E
Sbjct: 197 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE-------- 248
Query: 785 KLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSND 844
E + +G T E+ E E E++++E+E SN+ E S
Sbjct: 249 -----EEEEEEEEEEGST--------SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 295
Query: 845 KEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKS 904
+E++ + N L+ + +S FDR++ E ++ +EE
Sbjct: 296 EEEMSEDEERENENHLLV---------------------VPESRFDRDSGESEEAEEEVG 334
Query: 905 SSKPSNNA 912
P ++A
Sbjct: 335 EGTPQSSA 342
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 46.6 bits (109), Expect = 1e-04
Identities = 97/509 (19%), Positives = 187/509 (36%), Gaps = 74/509 (14%)
Query: 338 QAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHG 397
Q E + +AE A + + + E E R+ R +L +E + + G
Sbjct: 13 QKREEMRLEAERIAYQRNDDDEE----EAARERRRRARQERLRQKQEEESL--------G 60
Query: 398 NTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCS---EYRKSRKNGRLFCTRE 454
EV Q +++ K + + + A+F E + E R+ R L +E
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKE 120
Query: 455 NDP------IQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTL 508
DP + P +M +T ++EE++ ++ +R +E T+
Sbjct: 121 FDPTITDASLSLPSRRMQNDTAE--NETTEKEEKSESRQERYEIEE----------TETV 168
Query: 509 ICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCS 568
+ + N R + +K E+EE++ +K ++G + +V+ V+E +
Sbjct: 169 TKSYQKNDWRDAEENKKEDK----------EKEEEEEEKPKRGSIGENQVE-VMVEEKTT 217
Query: 569 EYRHY-----VRNGRLPCT---RENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPR 620
E + ++NG++ +E + +G D H + + + + AE R
Sbjct: 218 ESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEER 277
Query: 621 AKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERK 680
++K E +K+ DE R+ K +E + + + + Q+ EE K
Sbjct: 278 ERIKAEQDKKIADERARIEAEEKA-AAQERERREAEERERMREEEKRAAEERQRIKEEEK 336
Query: 681 RKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQC 740
R EE QR + AE R+++K E R + +
Sbjct: 337 RAAEERQRIK-----------EEEKRAAEERQRIKEEEKRAAEERQRARAEEEE------ 379
Query: 741 TMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRE-SDPVRGPD 799
KAK+E + K + + G+ + + N K + V
Sbjct: 380 ---KAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQ 436
Query: 800 GKTHGNKCTMCKEKLEREAAEKKKKEDED 828
G+ G K +EKL+ + KK+E +D
Sbjct: 437 GEEKGTKVQAKREKLQEDKPTFKKEEIKD 465
Score = 43.1 bits (100), Expect = 0.001
Identities = 102/522 (19%), Positives = 194/522 (37%), Gaps = 56/522 (10%)
Query: 268 RFSEENSKTDQNLGKAEEKTKVKR------EIVKLCSQYQNQAKNGILFCTRENDPIRGP 321
R +EEN K D+ + EE+ K KR ++ + + +++ + + +N I
Sbjct: 178 RDAEENKKEDKEK-EEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSE 236
Query: 322 DGKMHGNL---CSMCQAYFQAENEEKKKAEA-RAR---NKRESGKATSYAELCSEYRKLV 374
+ K + + E E+K++AEA RAR +RE KA ++ E ++
Sbjct: 237 EPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIE 296
Query: 375 RNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFE 434
K A ++ E + +EEEK+ E + R K + K A
Sbjct: 297 AEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 356
Query: 435 ELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKE 494
+ E K R E + + + + Q+ + K +++ +
Sbjct: 357 QRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGK 416
Query: 495 ICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEE---EEKKNDKEEKG 551
+E + Q ++ +G + K FK EE E+ K DKE K
Sbjct: 417 WVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 476
Query: 552 KVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEA 611
+V++ +++ E+ S+ ++ + +L T G G+ +T EA +
Sbjct: 477 EVKSFMDRKKGFTEVKSQNGEFMTH-KLKHTENTFSRPG--GRASVDTK---EAEGAPQV 530
Query: 612 KEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAV 671
+ +R E + + E E E ++ ++ Q L + +
Sbjct: 531 EAGKRLEELRRRRGETESEEFEKLKQKQQEAAL----------------------ELEEL 568
Query: 672 FQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDA 731
+K E RK EEE+QR ++E +E+++ R + + +
Sbjct: 569 KKKREERRKVLEEEEQRRKQ---EEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE- 624
Query: 732 DGKSYNNQCTMC------KAKLEREAERKNEYSRSRSNGTGS 767
DG S + + C K+E AE N+ S +S+G S
Sbjct: 625 DGLSDDKKPFKCFTPKGSSLKIEERAEFLNK-SVQKSSGVKS 665
Score = 39.7 bits (91), Expect = 0.013
Identities = 91/482 (18%), Positives = 184/482 (38%), Gaps = 111/482 (23%)
Query: 410 EEEEKKKKEGKSRNKR-----QSKSTASFEELCSEYRKSRKNGRLFCT---RENDPIQGP 461
EEEE+K K G + + K+T S EE S KNG++ +E + QG
Sbjct: 192 EEEEEKPKRGSIGENQVEVMVEEKTTESQEETVV---MSLKNGQISSEEPKQEEEREQGS 248
Query: 462 DGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPD 521
D H ++E++ RA+A+R + +E R++++ + +
Sbjct: 249 DEISHHEK-------MEEEDKERAEAERARLE---AEERERIK------AEQDKKIADER 292
Query: 522 GKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPC 581
++ + A + E EE++ +EE+ + E+ + + ++ +E R ++
Sbjct: 293 ARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRA 352
Query: 582 TRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERA----EPRAKVKREAEKETCDEFRR 637
E I+ + ++ A+E++RA E +AKV+ + + +E +
Sbjct: 353 AEERQRIKEEE---------------KRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKH 397
Query: 638 LLQNGKLFCTRENDPVRGP---DGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHG 694
+Q K+ + + G + K +K + AV +K+ EE+ K + +
Sbjct: 398 AMQETKIKGEKVEQKIEGKWVNEKKAQEDK--LQTAVLKKQGEEKGTKVQAKREKLQ--- 452
Query: 695 SSGGGGGNTQDECAEYREQMKNGRLSCTRE-SDPVRD--------ADGKSYNNQCTMCKA 745
+D+ +E++K+ ++ +E + V+ + KS N + K
Sbjct: 453 ---------EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKL 503
Query: 746 KLER-----------------------EAERKNEYSRSRSNGTGSESGKDT--------- 773
K EA ++ E R R T SE +
Sbjct: 504 KHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL 563
Query: 774 -CDEFRSQMKNGKLICTRESDPVRGPDGKT---HGNKCTMCKEKLER---EAAEKKKKED 826
+E + + + + + E + + + KE++ER EAAEK++K
Sbjct: 564 ELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMP 623
Query: 827 ED 828
ED
Sbjct: 624 ED 625
Score = 37.7 bits (86), Expect = 0.049
Identities = 69/369 (18%), Positives = 147/369 (39%), Gaps = 58/369 (15%)
Query: 542 EKKNDKEEKGKVEAEKVKREA----VQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHG 597
E + K E+ ++EAE++ + +E E R R RL +E + + + ++
Sbjct: 9 ELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEV 68
Query: 598 N--------------TCSMCE-----AFFQQEAKEKERAEPRAKVKREAEKETCDEFR-- 636
N T + E AF ++ A+ +ER + R + E +KE
Sbjct: 69 NAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDA 128
Query: 637 ------RLLQNG-----------KLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEER 679
R +QN K +E + + T + + + + E++
Sbjct: 129 SLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDK 188
Query: 680 KRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQ-----MKNGRLSCTRESDPVRDADGK 734
+++EEE+++ G +++ E +E+ +KNG++S +P ++ + +
Sbjct: 189 EKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQIS---SEEPKQEEERE 245
Query: 735 SYNNQCTMCKAKLEREAERKNEYSRSRSNGTG-----SESGKDTCDEFRSQMKNGKLICT 789
+++ + + K+E E + + E R+R +E K DE R++++ +
Sbjct: 246 QGSDEISHHE-KMEEEDKERAEAERARLEAEERERIKAEQDKKIADE-RARIEAEEKAAA 303
Query: 790 RESDPVRGPDGKTHGNKCTMCKEKLER-EAAEKKKKEDEDRSNTGERSNTGERSNDKEDL 848
+E + + + + E+ +R + EK+ E+ R E+ ER KE+
Sbjct: 304 QERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEE 363
Query: 849 CREFRSMQR 857
R QR
Sbjct: 364 KRAAEERQR 372
>gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo
sapiens]
Length = 97
Score = 46.6 bits (109), Expect = 1e-04
Identities = 18/41 (43%), Positives = 26/41 (63%)
Query: 111 CPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGEC 151
CP Y+ +CGT+ TYDN C LC E+ K+ +I +G+C
Sbjct: 57 CPGLYQPICGTNFITYDNPCILCVESLKSHGRIRFYHDGKC 97
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 46.2 bits (108), Expect = 1e-04
Identities = 109/613 (17%), Positives = 220/613 (35%), Gaps = 91/613 (14%)
Query: 260 LCAEIFKQRFSEENSKTDQNLGK--AEEKTK---VKREIVKLCSQYQNQAKNGILFCTRE 314
+ + K+ S+E S+ D+ K EEK K K++++K+ QY++ + RE
Sbjct: 926 IAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPERE 985
Query: 315 NDPIRGPDGKMHGNLCSMCQAYFQAENE----EKKKAEARARNKRESGKATSYAELCSEY 370
+C + Q +N EKK + R + ++ + + YAE
Sbjct: 986 E-------------ICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAE----- 1027
Query: 371 RKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKST 430
T + D + K N E+++ K GKS KRQ S+
Sbjct: 1028 ---------KSTGKGDSCDSSEDKKSKNGA-------YGREKKRCKLLGKSSRKRQDCSS 1071
Query: 431 ASFEEL------CSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERAR 484
+ E+ C+ K K L R + G++ S E + E +
Sbjct: 1072 SDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAE---ESSEDNK 1128
Query: 485 AKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKK 544
K +R ++K+ +++ RN T+ K A S + E+
Sbjct: 1129 KKKQRTSSKKKAVIVKEKKRNSLRTSTKR--------------KQADITSSSSSDIEDDD 1174
Query: 545 NDKEEKGKVEAEKVKREAVQELCSEYRHYVRNG-------RLPCT-----RENDPIEGLD 592
+ +G + +K+K + S + + ++ +P T +NDP +
Sbjct: 1175 QNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIA 1234
Query: 593 GKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDP 652
K+ + + + + E E + + ++ E+ DE + N + ++D
Sbjct: 1235 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSE----SDSDS 1290
Query: 653 VRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYRE 712
+ V E+ E K+ + ++ + G +++D ++++E
Sbjct: 1291 EESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSED--SDFQE 1348
Query: 713 QMKNGRLSCTRESDPVRDADGKSY----NNQCTMCKAKLEREAERKNEYSRSRSNGTGSE 768
+ +S + + R K N + K K R +++ S ++SN E
Sbjct: 1349 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1408
Query: 769 SGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDED 828
K+ +E + + + E+D + P + + +KL E K+E+E
Sbjct: 1409 EEKEEEEEEEEEEEEEE---EDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEER 1465
Query: 829 RSNTGERSNTGER 841
R ER E+
Sbjct: 1466 RKRIAEREREREK 1478
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 46.2 bits (108), Expect = 1e-04
Identities = 109/613 (17%), Positives = 220/613 (35%), Gaps = 91/613 (14%)
Query: 260 LCAEIFKQRFSEENSKTDQNLGK--AEEKTK---VKREIVKLCSQYQNQAKNGILFCTRE 314
+ + K+ S+E S+ D+ K EEK K K++++K+ QY++ + RE
Sbjct: 964 IAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPERE 1023
Query: 315 NDPIRGPDGKMHGNLCSMCQAYFQAENE----EKKKAEARARNKRESGKATSYAELCSEY 370
+C + Q +N EKK + R + ++ + + YAE
Sbjct: 1024 E-------------ICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAE----- 1065
Query: 371 RKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKST 430
T + D + K N E+++ K GKS KRQ S+
Sbjct: 1066 ---------KSTGKGDSCDSSEDKKSKNGA-------YGREKKRCKLLGKSSRKRQDCSS 1109
Query: 431 ASFEEL------CSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERAR 484
+ E+ C+ K K L R + G++ S E + E +
Sbjct: 1110 SDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAE---ESSEDNK 1166
Query: 485 AKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKK 544
K +R ++K+ +++ RN T+ K A S + E+
Sbjct: 1167 KKKQRTSSKKKAVIVKEKKRNSLRTSTKR--------------KQADITSSSSSDIEDDD 1212
Query: 545 NDKEEKGKVEAEKVKREAVQELCSEYRHYVRNG-------RLPCT-----RENDPIEGLD 592
+ +G + +K+K + S + + ++ +P T +NDP +
Sbjct: 1213 QNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIA 1272
Query: 593 GKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDP 652
K+ + + + + E E + + ++ E+ DE + N + ++D
Sbjct: 1273 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSE----SDSDS 1328
Query: 653 VRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYRE 712
+ V E+ E K+ + ++ + G +++D ++++E
Sbjct: 1329 EESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSED--SDFQE 1386
Query: 713 QMKNGRLSCTRESDPVRDADGKSY----NNQCTMCKAKLEREAERKNEYSRSRSNGTGSE 768
+ +S + + R K N + K K R +++ S ++SN E
Sbjct: 1387 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1446
Query: 769 SGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDED 828
K+ +E + + + E+D + P + + +KL E K+E+E
Sbjct: 1447 EEKEEEEEEEEEEEEEE---EDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEER 1503
Query: 829 RSNTGERSNTGER 841
R ER E+
Sbjct: 1504 RKRIAEREREREK 1516
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 45.8 bits (107), Expect = 2e-04
Identities = 59/269 (21%), Positives = 110/269 (40%), Gaps = 38/269 (14%)
Query: 533 ASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLD 592
A V + E E +K +EE+ K E +R+ +E+ E+ RE D +E L+
Sbjct: 112 ARVKEREHERRKRHREEQDKARREW-ERQKRREMAREHSR----------RERDRLEQLE 160
Query: 593 GKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQ--NGKLFCTR-E 649
K + Q+E KE+ER + +REA +E R + + + K+ +
Sbjct: 161 RKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWS 220
Query: 650 NDPVRGP-------DGKTHGNKCAMCKAVFQKENEER------KRKEEEDQRNAAGHGSS 696
P R P DG+ K V +++ EER + + +++ ++ SS
Sbjct: 221 RSPPRPPRERFELGDGR---------KPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 271
Query: 697 GGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNE 756
G +++E E E+ + G S + ES+ + + + + + E+ AE +E
Sbjct: 272 AESGSGSEEEEEEEEEEEEEG--STSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE 329
Query: 757 YSRSRSNGTGSESGKDTCDEFRSQMKNGK 785
S +E+ E R +G+
Sbjct: 330 EEMSEDEERENENHLLVVPESRFDRDSGE 358
Score = 43.1 bits (100), Expect = 0.001
Identities = 80/408 (19%), Positives = 159/408 (38%), Gaps = 82/408 (20%)
Query: 538 LEEEEKKNDKEEKGKVEAEK------VKREAVQELCSEYRHY-----VRNGRLPCTREN- 585
L+E++++ ++EEK +++ K KR++++E E R + +RN P RE+
Sbjct: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEE--GELRDHCMEITIRNS--PYRREDS 72
Query: 586 -----DPIEGLDGKIHGNTCSMCEAFFQQEAKEKE-----RAEPRAKVKREAEKETCDEF 635
+ + L K + +++ K KE R + R +R+ +E D+
Sbjct: 73 MEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKA 132
Query: 636 RRLLQNGKL------FCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRN 689
RR + K RE D + + K + + Q+E +ER+R+ EE ++
Sbjct: 133 RREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKE 192
Query: 690 AAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRD---ADGKSYNNQCTMCKAK 746
+++ Y +++K S + P DG+ + M +
Sbjct: 193 REARREVSAHHRTMRED---YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD 249
Query: 747 LEREAERKNEYSRSRSNGTGS--ESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHG 804
L + + ++ R S+ S ESG + +E E + +G T
Sbjct: 250 LLSDLQDISDSERKTSSAESSSAESGSGSEEE-------------EEEEEEEEEEGST-- 294
Query: 805 NKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLICT 864
E+ E E E++++E+E SN+ E S +E++ + N L+
Sbjct: 295 ------SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV-- 346
Query: 865 RENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNA 912
+ +S FDR++ E ++ +EE P ++A
Sbjct: 347 -------------------VPESRFDRDSGESEEAEEEVGEGTPQSSA 375
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 45.8 bits (107), Expect = 2e-04
Identities = 58/251 (23%), Positives = 93/251 (37%), Gaps = 55/251 (21%)
Query: 608 QQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAM 667
Q+E++ K+ R K KRE EKE R + GK + RG
Sbjct: 31 QRESERKKERREREKRKREREKE------RKRERGKKEKKKRKKRERG------------ 72
Query: 668 CKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDP 727
+ ERKRKE E QR ++ + R + K + R+
Sbjct: 73 -------KERERKRKEREKQR---------------KERREKERRKRKKEKKKRERKQRG 110
Query: 728 VRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLI 787
R+ K K + ERE E K R R + K E + + + GK
Sbjct: 111 RRERKKK---------KERKERERENKQRRERKRKKRRKKKRRK----ERKREKERGKRE 157
Query: 788 CTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKED 847
R+ + K N+ KE+ +E E+KK+ ++R ER +R D++
Sbjct: 158 RKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK--DRKTDRQT 215
Query: 848 LCREFRSMQRN 858
+ FR ++ +
Sbjct: 216 DSQVFRPLRES 226
Score = 38.1 bits (87), Expect = 0.038
Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 8/190 (4%)
Query: 719 LSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEY-SRSRSNGTGSESGKDTCDEF 777
+SC+ S P + + + K K ERE ERK E + + E GK+ +
Sbjct: 20 VSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR 79
Query: 778 RSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSN 837
+ + K K RE + + K + K++ RE +KK++++ +R N R
Sbjct: 80 KEREKQRKE--RREKERRKRKKEKKKRER----KQRGRRERKKKKERKERERENKQRRER 133
Query: 838 TGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERK 897
++ K+ R +R GK R+ K N+ + +E ERK
Sbjct: 134 KRKKRRKKKRRKERKREKER-GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
Query: 898 KKDEEKSSSK 907
K+ +++ K
Sbjct: 193 KERKKERRKK 202
Score = 36.6 bits (83), Expect = 0.11
Identities = 49/219 (22%), Positives = 86/219 (39%), Gaps = 47/219 (21%)
Query: 470 CSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKC 529
C+ E+ ++E R R K KRE KE E RG K K
Sbjct: 29 CTQRESERKKERREREKRKREREKERKRE-------------------RGKKEKKKRKKR 69
Query: 530 AMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIE 589
E E K+ ++E++ K EK +R+ +E + R + GR ++ + E
Sbjct: 70 ERGK-----ERERKRKEREKQRKERREKERRKRKKE--KKKRERKQRGRRERKKKKERKE 122
Query: 590 GLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRE 649
+E + K+R E + K +R+ ++ E +R + GK R+
Sbjct: 123 -------------------RERENKQRRERKRKKRRKKKRRK--ERKREKERGKRERKRK 161
Query: 650 NDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQR 688
+ K N+ K +KE ERK++ ++++R
Sbjct: 162 KRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200
Score = 32.0 bits (71), Expect = 2.7
Identities = 36/167 (21%), Positives = 66/167 (39%), Gaps = 13/167 (7%)
Query: 703 TQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAK------LEREAERKNE 756
TQ E +E+ + + RE + R+ K + + K ERE +RK
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 757 YSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLER 816
+ R + ++ R + K K RE + + + K + +++ +R
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
Query: 817 E------AAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQR 857
E ++KK++ E+R ER N ER ++E R R +R
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRER-NRKERKKERERKERRERKKER 195
>gi|94536774 serine peptidase inhibitor, Kazal type 9 [Homo sapiens]
Length = 86
Score = 45.1 bits (105), Expect = 3e-04
Identities = 19/57 (33%), Positives = 29/57 (50%)
Query: 95 LNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGEC 151
++C +KK C Y+ +CG+DGKTY N C C++ KT + G+C
Sbjct: 30 VDCSHYKKLPPGQQRFCHHMYDPICGSDGKTYKNDCFFCSKVKKTDGTLKFVHFGKC 86
Score = 38.5 bits (88), Expect = 0.029
Identities = 16/48 (33%), Positives = 24/48 (50%)
Query: 624 KREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAV 671
K+ + C +++L + FC DP+ G DGKT+ N C C V
Sbjct: 24 KQTKQMVDCSHYKKLPPGQQRFCHHMYDPICGSDGKTYKNDCFFCSKV 71
Score = 38.1 bits (87), Expect = 0.038
Identities = 19/48 (39%), Positives = 22/48 (45%)
Query: 356 ESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMC 403
E K T CS Y+KL + C DPI G DGK + N C C
Sbjct: 21 ECAKQTKQMVDCSHYKKLPPGQQRFCHHMYDPICGSDGKTYKNDCFFC 68
Score = 37.0 bits (84), Expect = 0.084
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 437 CSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMC 473
CS Y+K + FC DPI G DGK + N C C
Sbjct: 32 CSHYKKLPPGQQRFCHHMYDPICGSDGKTYKNDCFFC 68
Score = 35.8 bits (81), Expect = 0.19
Identities = 15/51 (29%), Positives = 24/51 (47%)
Query: 150 ECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAEL 200
EC + CS ++ + C DP+ G DGKT+ N C C+++
Sbjct: 21 ECAKQTKQMVDCSHYKKLPPGQQRFCHHMYDPICGSDGKTYKNDCFFCSKV 71
Score = 35.8 bits (81), Expect = 0.19
Identities = 14/42 (33%), Positives = 22/42 (52%)
Query: 225 CKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFK 266
C Y+K + FC DP+ G DG+ + N C C+++ K
Sbjct: 32 CSHYKKLPPGQQRFCHHMYDPICGSDGKTYKNDCFFCSKVKK 73
Score = 33.5 bits (75), Expect = 0.93
Identities = 12/38 (31%), Positives = 20/38 (52%)
Query: 706 ECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMC 743
+C+ Y++ + C DP+ +DGK+Y N C C
Sbjct: 31 DCSHYKKLPPGQQRFCHHMYDPICGSDGKTYKNDCFFC 68
Score = 32.3 bits (72), Expect = 2.1
Identities = 15/53 (28%), Positives = 24/53 (45%)
Query: 487 AKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLE 539
AK+ CS ++ C ++P+ G DGK + N C C+ V K +
Sbjct: 23 AKQTKQMVDCSHYKKLPPGQQRFCHHMYDPICGSDGKTYKNDCFFCSKVKKTD 75
Score = 32.3 bits (72), Expect = 2.1
Identities = 15/37 (40%), Positives = 17/37 (45%)
Query: 297 CSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMC 333
CS Y+ FC DPI G DGK + N C C
Sbjct: 32 CSHYKKLPPGQQRFCHHMYDPICGSDGKTYKNDCFFC 68
Score = 32.0 bits (71), Expect = 2.7
Identities = 12/39 (30%), Positives = 18/39 (46%)
Query: 774 CDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKE 812
C ++ + C DP+ G DGKT+ N C C +
Sbjct: 32 CSHYKKLPPGQQRFCHHMYDPICGSDGKTYKNDCFFCSK 70
Score = 31.2 bits (69), Expect = 4.6
Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 2/51 (3%)
Query: 553 VEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMC 603
+E K ++ V CS Y+ + C DPI G DGK + N C C
Sbjct: 20 IECAKQTKQMVD--CSHYKKLPPGQQRFCHHMYDPICGSDGKTYKNDCFFC 68
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 44.7 bits (104), Expect = 4e-04
Identities = 54/282 (19%), Positives = 104/282 (36%), Gaps = 19/282 (6%)
Query: 588 IEGLDG-KIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFC 646
+E LDG +++G + E + + R+ R++ + + + ++G
Sbjct: 157 LEKLDGTEVNGRKIRLVE---DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS 213
Query: 647 TRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDE 706
+ R G +K + +E+ R +++ + H S+G ++D+
Sbjct: 214 SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSH-SAGKSRSKSKDQ 272
Query: 707 CAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLE--------REAERKNEYS 758
E + N + + P R ++ + + E R E+ S
Sbjct: 273 AEE--KIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQS 330
Query: 759 RSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREA 818
RSRS G + + G+ ES K+ ++ K + +
Sbjct: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS 390
Query: 819 AEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGK 860
++KKKKED DRS +S + RS KE + S QR G+
Sbjct: 391 SKKKKKEDTDRS----QSRSPSRSVSKEREHAKSESSQREGR 428
Score = 31.2 bits (69), Expect = 4.6
Identities = 50/252 (19%), Positives = 101/252 (40%), Gaps = 38/252 (15%)
Query: 270 SEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNL 329
+EE + + N+GK + ++ R K S+ ++Q + R + RG +
Sbjct: 273 AEEKIQNNDNVGKPKSRSP-SRHKSKSKSRSRSQER-------RVEEEKRGSVSRGRSQE 324
Query: 330 CSMCQAYFQAENEEKKKAEARARNK---RESGKATSYAELCSEYR---KLVRNGKLACTR 383
S+ Q+ ++ ++ ++ +R+R+K + G+ S E S R K R+ K R
Sbjct: 325 KSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKR 384
Query: 384 ENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKS 443
++ +A +KKKKE R++ +S S + +E E+ KS
Sbjct: 385 DS----------------------KAGSSKKKKKEDTDRSQSRSPSRSVSKE--REHAKS 420
Query: 444 RKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQV 503
+ R + + + + S + E R+R+K+ + S R
Sbjct: 421 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS 480
Query: 504 RNGTLICTREHN 515
R+ + +R H+
Sbjct: 481 RSPSRSRSRSHS 492
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,804,406
Number of Sequences: 37866
Number of extensions: 2122672
Number of successful extensions: 13742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 290
Number of HSP's that attempted gapping in prelim test: 10336
Number of HSP's gapped (non-prelim): 2271
length of query: 916
length of database: 18,247,518
effective HSP length: 111
effective length of query: 805
effective length of database: 14,044,392
effective search space: 11305735560
effective search space used: 11305735560
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.