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Search of human proteins with 188595687
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188595687 gamma filamin isoform b [Homo sapiens]
(2692 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188595687 gamma filamin isoform b [Homo sapiens] 5489 0.0
gi|116805322 gamma filamin isoform a [Homo sapiens] 5472 0.0
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens] 3335 0.0
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens] 3311 0.0
gi|105990514 filamin B, beta (actin binding protein 278) [Homo s... 3190 0.0
gi|239755812 PREDICTED: similar to spectrin, beta, non-erythrocy... 192 3e-48
gi|4557241 actinin, alpha 3 [Homo sapiens] 164 8e-40
gi|12025678 actinin, alpha 4 [Homo sapiens] 160 1e-38
gi|4501893 actinin, alpha 2 [Homo sapiens] 158 8e-38
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] 154 1e-36
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens] 154 1e-36
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens] 154 1e-36
gi|67782321 spectrin beta isoform a [Homo sapiens] 147 1e-34
gi|67782319 spectrin beta isoform b [Homo sapiens] 147 1e-34
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 147 1e-34
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 147 2e-34
gi|33188445 microfilament and actin filament cross-linker protei... 145 7e-34
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 143 2e-33
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 142 3e-33
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 142 4e-33
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 141 8e-33
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 141 8e-33
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 141 8e-33
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 141 8e-33
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 141 8e-33
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 141 8e-33
gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi... 139 3e-32
gi|221316624 dystonin isoform 4 [Homo sapiens] 139 5e-32
gi|221316622 dystonin isoform 3 [Homo sapiens] 139 5e-32
gi|221316618 dystonin isoform 2 [Homo sapiens] 139 5e-32
>gi|188595687 gamma filamin isoform b [Homo sapiens]
Length = 2692
Score = 5489 bits (14239), Expect = 0.0
Identities = 2692/2692 (100%), Positives = 2692/2692 (100%)
Query: 1 MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL 60
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL
Sbjct: 1 MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL 60
Query: 61 QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK 120
QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK
Sbjct: 61 QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK 120
Query: 121 AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN 180
AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
Sbjct: 121 AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN 180
Query: 181 FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI 240
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI
Sbjct: 181 FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI 240
Query: 241 VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV 300
VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV
Sbjct: 241 VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV 300
Query: 301 QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE 360
QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
Sbjct: 301 QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE 360
Query: 361 RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR 420
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR
Sbjct: 361 RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR 420
Query: 421 RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS 480
RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS
Sbjct: 421 RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS 480
Query: 481 GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV 540
GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
Sbjct: 481 GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV 540
Query: 541 VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE 600
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE
Sbjct: 541 VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE 600
Query: 601 VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP 660
VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP
Sbjct: 601 VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP 660
Query: 661 APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP 720
APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
Sbjct: 661 APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP 720
Query: 721 NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK 780
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK
Sbjct: 721 NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK 780
Query: 781 ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR 840
ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR
Sbjct: 781 ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR 840
Query: 841 YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA 900
YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
Sbjct: 841 YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA 900
Query: 901 KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV
Sbjct: 901 KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
Query: 961 APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG 1020
APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG
Sbjct: 961 APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG 1020
Query: 1021 AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP 1080
AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
Sbjct: 1021 AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP 1080
Query: 1081 APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI 1140
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI
Sbjct: 1081 APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI 1140
Query: 1141 PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA 1200
PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA
Sbjct: 1141 PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA 1200
Query: 1201 EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV 1260
EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
Sbjct: 1201 EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV 1260
Query: 1261 EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE 1320
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE
Sbjct: 1261 EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE 1320
Query: 1321 EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT 1380
EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT
Sbjct: 1321 EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT 1380
Query: 1381 GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV 1440
GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
Sbjct: 1381 GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV 1440
Query: 1441 VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT 1500
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT
Sbjct: 1441 VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT 1500
Query: 1501 HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV 1560
HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV
Sbjct: 1501 HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV 1560
Query: 1561 EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE 1620
EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
Sbjct: 1561 EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE 1620
Query: 1621 IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC 1680
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC
Sbjct: 1621 IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC 1680
Query: 1681 TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLATEEPVV 1740
TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLATEEPVV
Sbjct: 1681 TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLATEEPVV 1740
Query: 1741 PVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGL 1800
PVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGL
Sbjct: 1741 PVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGL 1800
Query: 1801 HQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLS 1860
HQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLS
Sbjct: 1801 HQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLS 1860
Query: 1861 LAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMR 1920
LAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMR
Sbjct: 1861 LAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMR 1920
Query: 1921 TSQLNVGTSTDVSLKITESDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEH 1980
TSQLNVGTSTDVSLKITESDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEH
Sbjct: 1921 TSQLNVGTSTDVSLKITESDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEH 1980
Query: 1981 VVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGG 2040
VVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGG
Sbjct: 1981 VVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGG 2040
Query: 2041 LGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGR 2100
LGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGR
Sbjct: 2041 LGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGR 2100
Query: 2101 MKESITRRRQAPSIATIGSTCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEI 2160
MKESITRRRQAPSIATIGSTCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEI
Sbjct: 2101 MKESITRRRQAPSIATIGSTCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEI 2160
Query: 2161 SKTRGGETKREVRVEESTQVGGDPFPAVFGDFLGRERLGSFGSITRQQEGEASSQDMTAQ 2220
SKTRGGETKREVRVEESTQVGGDPFPAVFGDFLGRERLGSFGSITRQQEGEASSQDMTAQ
Sbjct: 2161 SKTRGGETKREVRVEESTQVGGDPFPAVFGDFLGRERLGSFGSITRQQEGEASSQDMTAQ 2220
Query: 2221 VTSPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGG 2280
VTSPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGG
Sbjct: 2221 VTSPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGG 2280
Query: 2281 AHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSY 2340
AHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSY
Sbjct: 2281 AHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSY 2340
Query: 2341 VVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQL 2400
VVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQL
Sbjct: 2341 VVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQL 2400
Query: 2401 NGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFK 2460
NGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFK
Sbjct: 2401 NGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFK 2460
Query: 2461 IRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCR 2520
IRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCR
Sbjct: 2461 IRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCR 2520
Query: 2521 ECPEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVET 2580
ECPEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVET
Sbjct: 2521 ECPEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVET 2580
Query: 2581 VTKSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVH 2640
VTKSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVH
Sbjct: 2581 VTKSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVH 2640
Query: 2641 GPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP 2692
GPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP
Sbjct: 2641 GPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP 2692
>gi|116805322 gamma filamin isoform a [Homo sapiens]
Length = 2725
Score = 5472 bits (14195), Expect = 0.0
Identities = 2692/2725 (98%), Positives = 2692/2725 (98%), Gaps = 33/2725 (1%)
Query: 1 MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL 60
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL
Sbjct: 1 MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL 60
Query: 61 QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK 120
QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK
Sbjct: 61 QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK 120
Query: 121 AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN 180
AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
Sbjct: 121 AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN 180
Query: 181 FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI 240
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI
Sbjct: 181 FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI 240
Query: 241 VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV 300
VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV
Sbjct: 241 VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV 300
Query: 301 QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE 360
QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
Sbjct: 301 QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE 360
Query: 361 RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR 420
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR
Sbjct: 361 RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR 420
Query: 421 RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS 480
RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS
Sbjct: 421 RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS 480
Query: 481 GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV 540
GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
Sbjct: 481 GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV 540
Query: 541 VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE 600
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE
Sbjct: 541 VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE 600
Query: 601 VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP 660
VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP
Sbjct: 601 VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP 660
Query: 661 APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP 720
APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
Sbjct: 661 APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP 720
Query: 721 NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK 780
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK
Sbjct: 721 NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK 780
Query: 781 ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR 840
ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR
Sbjct: 781 ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR 840
Query: 841 YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA 900
YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
Sbjct: 841 YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA 900
Query: 901 KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV
Sbjct: 901 KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
Query: 961 APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG 1020
APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG
Sbjct: 961 APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG 1020
Query: 1021 AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP 1080
AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
Sbjct: 1021 AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP 1080
Query: 1081 APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI 1140
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI
Sbjct: 1081 APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI 1140
Query: 1141 PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA 1200
PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA
Sbjct: 1141 PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA 1200
Query: 1201 EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV 1260
EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
Sbjct: 1201 EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV 1260
Query: 1261 EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE 1320
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE
Sbjct: 1261 EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE 1320
Query: 1321 EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT 1380
EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT
Sbjct: 1321 EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT 1380
Query: 1381 GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV 1440
GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
Sbjct: 1381 GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV 1440
Query: 1441 VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT 1500
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT
Sbjct: 1441 VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT 1500
Query: 1501 HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV 1560
HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV
Sbjct: 1501 HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV 1560
Query: 1561 EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE 1620
EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
Sbjct: 1561 EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE 1620
Query: 1621 IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC 1680
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC
Sbjct: 1621 IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC 1680
Query: 1681 TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVL------- 1733
TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVL
Sbjct: 1681 TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPH 1740
Query: 1734 --------------------------ATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG 1767
ATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
Sbjct: 1741 EEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG 1800
Query: 1768 EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSR 1827
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSR
Sbjct: 1801 EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSR 1860
Query: 1828 HVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLP 1887
HVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLP
Sbjct: 1861 HVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLP 1920
Query: 1888 TAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTAS 1947
TAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTAS
Sbjct: 1921 TAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTAS 1980
Query: 1948 IRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGD 2007
IRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGD
Sbjct: 1981 IRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGD 2040
Query: 2008 ASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTY 2067
ASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTY
Sbjct: 2041 ASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTY 2100
Query: 2068 CPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKI 2127
CPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKI
Sbjct: 2101 CPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKI 2160
Query: 2128 PGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA 2187
PGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA
Sbjct: 2161 PGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA 2220
Query: 2188 VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVP 2247
VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVP
Sbjct: 2221 VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVP 2280
Query: 2248 QEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTR 2307
QEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTR
Sbjct: 2281 QEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTR 2340
Query: 2308 EAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVP 2367
EAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVP
Sbjct: 2341 EAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVP 2400
Query: 2368 VASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD 2427
VASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD
Sbjct: 2401 VASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD 2460
Query: 2428 SDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTT 2487
SDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTT
Sbjct: 2461 SDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTT 2520
Query: 2488 GVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGP 2547
GVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGP
Sbjct: 2521 GVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGP 2580
Query: 2548 QHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVT 2607
QHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVT
Sbjct: 2581 QHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVT 2640
Query: 2608 RGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKE 2667
RGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKE
Sbjct: 2641 RGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKE 2700
Query: 2668 KGDYILIVKWGDESVPGSPFKVKVP 2692
KGDYILIVKWGDESVPGSPFKVKVP
Sbjct: 2701 KGDYILIVKWGDESVPGSPFKVKVP 2725
>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
Length = 2647
Score = 3335 bits (8647), Expect = 0.0
Identities = 1682/2655 (63%), Positives = 1997/2655 (75%), Gaps = 112/2655 (4%)
Query: 3 NNSGYSDAGLGLGDETD----EMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLT 58
+ +G S AG G D EMP+TEKDLAEDAPWKKIQQNTFTRWCNEHLKCV KR+
Sbjct: 6 SRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIA 65
Query: 59 DLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSID 118
+LQ DLSDGLRLIALLEVLSQK+M+RK + RP FRQM+LENVSVALEFL+RE IKLVSID
Sbjct: 66 NLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSID 125
Query: 119 SKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPI 178
SKAIVDGNLKLILGLIWTLILHYSISMPMW++E+DE+A+KQTPKQRLLGWIQNK+PQLPI
Sbjct: 126 SKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPI 185
Query: 179 TNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPE 238
TNF+RDWQ G+ALGALVD+CAPGLCPDW++WD ++PV NAREAMQQADDWLG+PQVI PE
Sbjct: 186 TNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPE 245
Query: 239 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHF 298
EIVDPNVDEHSVMTYLSQFPKAKLKPGAP+R K LNPKKA AYGPGIEP GN V + A F
Sbjct: 246 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPK-LNPKKARAYGPGIEPTGNMVKKRAEF 304
Query: 299 TVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQN 358
TV+T AG GEVLVY+EDP GH EEAKV NNDK+RT++V YVP+V G HKVTVLFAGQ+
Sbjct: 305 TVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQH 364
Query: 359 IERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQ 418
I +SPFEV V + GDA+KV+A+GPGLEP GN+ANK TYF+I+TAGAGTG+V VVI DP
Sbjct: 365 IAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPM 424
Query: 419 GRRDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACR 478
G++ TVE LE +GDST+RC+Y+P MEG HTVHV FAG PI RSP+ V V +ACNP+ACR
Sbjct: 425 GQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACR 484
Query: 479 ASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYY 538
A GRGLQPKGVRVKE ADFKV+TKGAGSGELKVTVKGPKG EE VK ++ GDGV+ EYY
Sbjct: 485 AVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKG-EERVKQKDLGDGVYGFEYY 543
Query: 539 PVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIG 598
P+VPG Y+VTITWGG I RSPFEV+V E G QKVRAWGPGLE G VGKSADFVVEAIG
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 599 TEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHI 658
+VGTLGFS+EGPSQAKIECDDKGDGSCDVRYWP E GEYAVHV+C+ EDIR SPF+A I
Sbjct: 604 DDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADI 663
Query: 659 LPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKV 718
AP D PD+VKA GPGLE TG V+KPAEFT+DA+ GK L++ QD +GCP++ V
Sbjct: 664 RDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEALV 723
Query: 719 IPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTG 778
NG+GT+ CSYVP KP+KHT ++SWGGV++P SPFRVNVG GSHP +VKVYGPGV KTG
Sbjct: 724 KDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTG 783
Query: 779 LKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGA 838
LKA+EPTYFTVDC+EAGQGDVSIGIKCAPGVVGPAEADIDFDII+NDNDTFTVKYTP GA
Sbjct: 784 LKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGA 843
Query: 839 GRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAG 898
G YTIMVLFA+Q P SP +KV+PSHDASKVKAEGPGL+RTGVE+GKPTHFTV K AG
Sbjct: 844 GSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG 903
Query: 899 KAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVV 958
K KLDVQF+G KG+ VRD +IID+HD +YTVKYT VQQG + V VTYGGDP+PKSPF V
Sbjct: 904 KGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSV 963
Query: 959 NVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPG 1018
V+P LDLSKIKV GL KV VG++Q F+V ++GAGGQG++ ++ PS +PCK+EPG
Sbjct: 964 AVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPG 1023
Query: 1019 GGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVG 1078
GA+ VR++P EEGPY+V++TYDG PVPGSPF +E V P PSKV A+GPGL+GG G
Sbjct: 1024 LGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAG 1083
Query: 1079 TPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEA 1138
+PA F+IDTKGAGTGGLGLTVEGPCEA++EC DNGDG+C+VSY+PTEPG+Y INILFA+
Sbjct: 1084 SPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADT 1143
Query: 1139 HIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGV 1198
HIPGSPFKA + P FD SKV+ SGPGLER GE F VDCS AG AELTIEI S+AG+
Sbjct: 1144 HIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGL 1203
Query: 1199 KAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGP 1258
AEV I ++ DGT+ ITY P PG YT+TIKYGG PVP FP+++ V+PAVDTSGV+ GP
Sbjct: 1204 PAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGP 1263
Query: 1259 GVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTA 1318
G+E GV RE TTEF+VDAR+LT TGG HV ARV NPSG T+TYV D GDG Y+V+YT
Sbjct: 1264 GIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTP 1323
Query: 1319 YEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGA 1378
YEEG+H V+V YD VP SPF+V VTEGCDP+RVR GPG++ G NK N+FTVETRGA
Sbjct: 1324 YEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGA 1383
Query: 1379 GTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVK 1438
GTGGLGLA+EGPSEAKMSC DNKDGSC+VEYIP+ G Y +N+T+GG +PGSPF+VPV
Sbjct: 1384 GTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVH 1443
Query: 1439 DVVDPGKVKCSGPGLGAG-VRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNG 1497
DV D KVKCSGPGL G VRA +PQ+F VD S+AG APLQV V GP G+ EPV+V DN
Sbjct: 1444 DVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNA 1503
Query: 1498 DGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPAS 1557
DGT TV+Y P+ +GPY+++V Y D+EVPRSPFK+KVLP HDASKV+ASGPGLN +G+PAS
Sbjct: 1504 DGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPAS 1563
Query: 1558 LPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYG 1617
LPVEFTIDA+DAGEGLL VQI DPEGKPKK +I+DN DGTYTV+Y+PD++GRYTI IKYG
Sbjct: 1564 LPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYG 1623
Query: 1618 GDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGK 1677
GDEIP+SP+R+ A+PTGDASKC VTVSIGGHGLGA +GP IQIG+ETVITVD KAAG+GK
Sbjct: 1624 GDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGK 1683
Query: 1678 VTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVL---- 1733
VTCTV TPDG+E+DVDVVEN DGTFDI+YTAP+PGKYVI +RFGGEH+PNSPF V
Sbjct: 1684 VTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAG 1743
Query: 1734 ----------------------------ATEEPVVPVEPME-SMLRPFNLVIPFAVQKGE 1764
A E P+V V ++ + LRPF+LVIPF ++KGE
Sbjct: 1744 DQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGE 1803
Query: 1765 LTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAI 1824
+TGEVRMPSGK A+P ITDNKDGT+TVRYAP+E GLH+M I+YD HIPGSPLQFYVD +
Sbjct: 1804 ITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYV 1863
Query: 1825 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVS 1884
N HV+AYGPGL+HG+VNKPATFT+ TKDAGEGGLSLA+EGPSKAEI+C DN+DGTC+VS
Sbjct: 1864 NCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVS 1923
Query: 1885 YLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQL 1944
YLP PGDYSI+V+++++H+PGSPFTA++TGDDSMR S L VG++ D+ + I+E+DLS L
Sbjct: 1924 YLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLL 1983
Query: 1945 TASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSE 2004
TA++ PSG EEPCLLKRL N H+GISF PKE GEH+V V+K+G+HV +SP +++ SE
Sbjct: 1984 TATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSE 2043
Query: 2005 IGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCK 2064
IGDAS+VRV G+GL EGHTF+ AEFI+DTR+AGYGGL LSIEGPSKVDIN ED+EDGTC+
Sbjct: 2044 IGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCR 2103
Query: 2065 VTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLN 2124
VTYCPTEPG YIINIKFAD+HVPGSPF+VKVTGEGR+KESITRRR+APS+A +GS CDL+
Sbjct: 2104 VTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHCDLS 2163
Query: 2125 LKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGET-KREVRVEESTQ-VGG 2182
LKIP Q ++AQ T + T + E V V+ Q V G
Sbjct: 2164 LKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPG 2223
Query: 2183 DPFPAVFGDF----LGRERLGSFGSITRQQEG----------EASSQDMTAQVTSPSGKV 2228
PF G + R G G + R + G EA + + V PS K
Sbjct: 2224 SPFQFTVGPLGEGGAHKVRAGGPG-LERAEAGVPAEFSIWTREAGAGGLAIAVEGPS-KA 2281
Query: 2229 EAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGG 2288
E + + +D + V +V QE G + V+VK+ +H+P SPF V G A ++
Sbjct: 2282 EIS-FEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVAS-PSGDARRLTVSS 2339
Query: 2289 TGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKA--EIAFEDRKDGSCGVSYVVQEPG 2346
PA F++ + G + V PS A E + V ++ +E G
Sbjct: 2340 LQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENG 2398
Query: 2347 DYEVSIKFNDEHIPDSPFVVPVA--SLSDDARRLTVTSLQETGLKVNQPASFAVQL-NGA 2403
Y + +KFN HIP SPF + V D ++ G PA F V N
Sbjct: 2399 VYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAG 2458
Query: 2404 RGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGA-HIPGSPFKIR 2462
G + + PS +C + + + + + P G + I +K+ G HI GSPFK +
Sbjct: 2459 AGALSVTIDGPSKVKMDC---QECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAK 2515
Query: 2463 V-----------GEQS--------------QAGDPG-------LVSAYGPGLEGGTTGVS 2490
V E S Q G PG V A G GL G
Sbjct: 2516 VTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQK 2575
Query: 2491 SEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHV------VTYTPMAPGNYLIAIKY 2544
S F V+ AG+ L V + GP + C E HV V+Y G Y + +K+
Sbjct: 2576 SSFTVDCSKAGNNMLLVGVHGP---RTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKW 2632
Query: 2545 GGPQHIVGSPFKAKV 2559
G +HI GSP++ V
Sbjct: 2633 -GDEHIPGSPYRVVV 2646
Score = 1586 bits (4106), Expect = 0.0
Identities = 963/2447 (39%), Positives = 1345/2447 (54%), Gaps = 213/2447 (8%)
Query: 377 KVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTF 436
K A GPG+EP GN+ K F + T AG G+V V + DP G ++ +V + + TF
Sbjct: 283 KARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTF 342
Query: 437 RCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEAC-NPNACRASGRGLQPKGVRVKEVA 495
Y P + G H V V FAG I +SPF V+V ++ + + A G GL+P G +
Sbjct: 343 SVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTT 402
Query: 496 DFKVFTKGAGSGELKVTVKGP---KGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWG 552
F++FT GAG+GE++V ++ P KGT EP ++ GD + C Y P + G + V +T+
Sbjct: 403 YFEIFTAGAGTGEVEVVIQDPMGQKGTVEP-QLEARGDSTYRCSYQPTMEGVHTVHVTFA 461
Query: 553 GYAIPRSPFEVQVSPEAGVQKVRAWGPGLETG--QVGKSADFVVEAIGTEVGTLGFSIEG 610
G IPRSP+ V V RA G GL+ +V ++ADF V G G L +++G
Sbjct: 462 GVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKG 521
Query: 611 PS-QAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDK 669
P + +++ D GDG Y+P PG Y V + ++I SPF + +C K
Sbjct: 522 PKGEERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKV---GTECGNQK 578
Query: 670 VKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCS 729
V+A+GPGLE G +V K A+F ++A G L + I+ GDG+
Sbjct: 579 VRAWGPGLE--GGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECD--DKGDGSCDVR 634
Query: 730 YVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGS---HPERVKVYGPGVEKTGLKANEPTY 786
Y P + ++ + + ++ SPF ++ + HP+RVK GPG+EKTG+ N+P
Sbjct: 635 YWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAE 694
Query: 787 FTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVL 846
FTVD G+ + + ++ G P EA + N N T++ Y P ++T MV
Sbjct: 695 FTVDAKHGGKAPLRVQVQDNEGC--PVEALVK----DNGNGTYSCSYVPRKPVKHTAMVS 748
Query: 847 FANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQF 906
+ IP SPF + V +KVK GPG+ +TG++ +PT+FTV AG+ + +
Sbjct: 749 WGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAGQGDVSIGI 808
Query: 907 ------AGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
G A+ ++ DF+II N + ++TVKYT G+ + V + P SP V V
Sbjct: 809 KCAPGVVGPAEADI--DFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKV 866
Query: 961 APPLDLSKIKVQG---LNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEP 1017
P D SK+K +G + V +G+ F+VN + AG +G+LDV+ + ++ ++
Sbjct: 867 EPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG-KGKLDVQFSGLTKGDAVRDVDI 925
Query: 1018 GGGAE-AQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGL 1076
+ V+Y P ++GP V++TY G P+P SPF+V D SK+ G G K
Sbjct: 926 IDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVD- 984
Query: 1077 VGTPAPFSIDTKGAG-TGGLGLTVEGPCEAKIECQDN---GDGSCAVSYLPTEPGEYTIN 1132
VG F++ +KGAG G + + GP A + C+ G + V +LP E G Y +
Sbjct: 985 VGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSVVRFLPREEGPYEVE 1044
Query: 1133 ILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEI 1192
+ + +PGSPF PSKV+A GPGL+ G G A FT+D AG L + +
Sbjct: 1045 VTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTV 1104
Query: 1193 LSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSG 1252
+ E L +N DGT ++Y P PG Y I I + +P P + HV P D S
Sbjct: 1105 EGPCEAQLECL--DNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASK 1162
Query: 1253 VKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTY 1312
VK SGPG+E EV +F VD S G +T + + +G + Y+ D+GDGT+
Sbjct: 1163 VKCSGPGLE-RATAGEVG-QFQVDCSS---AGSAELTIEICSEAGLPAEVYIQDHGDGTH 1217
Query: 1313 RVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEG-GLVNKAN-R 1370
+ Y G + V + Y VP P ++ V D + V+ +GPG+EG G+ +A
Sbjct: 1218 TITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTE 1277
Query: 1371 FTVETRG-AGTGG--LGLAIEGPSE--AKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGG 1425
F+V+ R TGG + + PS + +D DG VEY P+ G + V++T+ G
Sbjct: 1278 FSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTPYEEGLHSVDVTYDG 1337
Query: 1426 RPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPT 1485
P+P SPF+VPV + DP +V+ GPG+ +G + P FTV+ AG L +AV GP+
Sbjct: 1338 SPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNK-PNKFTVETRGAGTGGLGLAVEGPS 1396
Query: 1486 GVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRAS 1545
+ DN DG+ +V Y P G Y++ V Y +VP SPFK+ V DASKV+ S
Sbjct: 1397 EAK--MSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCS 1454
Query: 1546 GPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPD 1605
GPGL+ + A+LP F +D AG L V++ P+G + ++ DN DGT TV+Y+P
Sbjct: 1455 GPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPS 1514
Query: 1606 MSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETV 1665
G Y+I++ YG +E+P SPF++ LPT DASK V G GL P
Sbjct: 1515 REGPYSISVLYGDEEVPRSPFKVKVLPTHDASK----VKASGPGLNTTGVPA---SLPVE 1567
Query: 1666 ITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHI 1725
T+DAK AGEG + ++ P+G + +NHDGT+ + Y G+Y I I++GG+ I
Sbjct: 1568 FTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEI 1627
Query: 1726 PNSPFHVLAT------------------------------EEPVVPVEPMESMLRPFNLV 1755
P SP+ V A EE V+ V+
Sbjct: 1628 PFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTK---------- 1677
Query: 1756 IPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGS 1815
A KG++T V P G ++ +N+DGT + Y + G + + +++ G H+P S
Sbjct: 1678 ---AAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNS 1734
Query: 1816 PLQFYVDAINSRHVSAYGP---------------------------GLSHGMVNKPATFT 1848
P Q V A+ S P G++ V F
Sbjct: 1735 PFQ--VTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFD 1792
Query: 1849 IV---TKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIP 1905
+V T GE + + A+ T DNKDGT TV Y P+ G + + +R+D+ HIP
Sbjct: 1793 LVIPFTIKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIP 1852
Query: 1906 GSPFTAKITGDDSMRTSQLNVGTSTDVSLK-----ITESDLSQ--LTASIRAPSGNEEPC 1958
GSP + + + G + V K + D + L+ +I PS E C
Sbjct: 1853 GSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISC 1912
Query: 1959 LLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGL 2018
+ + +S+ P G++ + V+ + +HV SPF V + S ++V
Sbjct: 1913 TDNQ--DGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGS--- 1967
Query: 2019 SEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINC--EDMEDGTCKVTYCPTEPGTYI 2076
A+ ++ L ++ PS + C + + +G +++ P E G ++
Sbjct: 1968 -------AADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHL 2020
Query: 2077 INIKFADKHVPGSPFTV-------------KVTGEGRMKESITRRRQAPSIATIGSTCDL 2123
+++K +HV SP V +V+G+G + + L
Sbjct: 2021 VHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGL 2080
Query: 2124 NLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGD 2183
+L I G ++ + T R T G ++ + V G
Sbjct: 2081 SLSIEGP-----------SKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQ-HVPGS 2128
Query: 2184 PFPA-VFGDFLGRERLGSFGSITRQQEG-----------------EASSQDMTAQVTSPS 2225
PF V G+ +E SITR++ E S QDMTAQVTSPS
Sbjct: 2129 PFSVKVTGEGRVKE------SITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPS 2182
Query: 2226 GKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVR 2285
GK AEIVEGE+ Y +RFVP EMG HTV+VKY+GQHVPGSPFQFTVGPLGEGGAHKVR
Sbjct: 2183 GKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVR 2242
Query: 2286 AGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEP 2345
AGG GLER AGVPAEFSIWTREAGAGGL+IAVEGPSKAEI+FEDRKDGSCGV+YVVQEP
Sbjct: 2243 AGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEP 2302
Query: 2346 GDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARG 2405
GDYEVS+KFN+EHIPDSPFVVPVAS S DARRLTV+SLQE+GLKVNQPASFAV LNGA+G
Sbjct: 2303 GDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKG 2362
Query: 2406 VIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGE 2465
IDA+VH+PSGA+EECYV+E+D DK+ +RFIP ENGV+ IDVKFNG HIPGSPFKIRVGE
Sbjct: 2363 AIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGE 2422
Query: 2466 QSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEG 2525
GDPGLVSAYG GLEGG TG +EF+VNT NAG+GALSVTIDGPSKV++DC+ECPEG
Sbjct: 2423 PGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEG 2482
Query: 2526 HVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSS 2585
+ VTYTPMAPG+YLI+IKYGGP HI GSPFKAKVTGPRL HSLHETS+V V+++TK++
Sbjct: 2483 YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKAT 2542
Query: 2586 SSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTP 2645
+ + + +DASKVV +G GLS+A+VGQK+SFTVDCSKAG NM++VGVHGP+TP
Sbjct: 2543 CA--PQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTP 2600
Query: 2646 CEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP 2692
CEE+ VKH+G+R+Y+V+Y +K+KG+Y L+VKWGDE +PGSP++V VP
Sbjct: 2601 CEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP 2647
Score = 906 bits (2342), Expect = 0.0
Identities = 730/2366 (30%), Positives = 1066/2366 (45%), Gaps = 276/2366 (11%)
Query: 473 NPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDG- 531
NP RA G G++P G VK+ A+F V T+ AG GE+ V V+ P G +E KV D
Sbjct: 280 NPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKN 339
Query: 532 -VFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQVSPEAG-VQKVRAWGPGLE-TGQVG- 587
F Y P V G + VT+ + G I +SPFEV V G KV A GPGLE +G +
Sbjct: 340 RTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIAN 399
Query: 588 KSADFVVEAIGTEVGTLGFSIEGPSQAK----IECDDKGDGSCDVRYWPTEPGEYAVHVI 643
K+ F + G G + I+ P K + + +GD + Y PT G + VHV
Sbjct: 400 KTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVT 459
Query: 644 CDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLK 703
I SP+ + A C P +A G GL+P G V + A+F + + AG G+LK
Sbjct: 460 FAGVPIPRSPYTVTVGQA---CNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELK 516
Query: 704 LYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSH 763
+ + G +K GDG + Y P P + + I+WGG N+ +SPF V VG
Sbjct: 517 VTVKGPKG-EERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECG 575
Query: 764 PERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIK 823
++V+ +GPG+E G + F V+ G + ++ GP++A I+ D
Sbjct: 576 NQKVRAWGPGLE--GGVVGKSADFVVEAIGDDVGTLGFSVE------GPSQAKIECD--D 625
Query: 824 NDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKV-DPSHD--ASKVKAEGPGLNRT 880
+ + V+Y P AG Y + VL +++I SPF + D D +VKA GPGL +T
Sbjct: 626 KGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKT 685
Query: 881 GVEVGKPTHFTVLTKGAGKAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNM 940
GV V KP FTV K GKA L VQ V + + DN + +Y+ Y +
Sbjct: 686 GVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPV--EALVKDNGNGTYSCSYVPRKPVKH 743
Query: 941 AVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQG---LNSKVAVGQEQAFSVNTRGAGGQG 997
V++GG +P SPF VNV +K+KV G + + + F+V+ AG QG
Sbjct: 744 TAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAG-QG 802
Query: 998 QLDVRMTSPSRRPIPCKLEPG--GGAEAQ-------------AVRYMPPEEGPYKVDITY 1042
+ + + K PG G AEA V+Y P G Y + + +
Sbjct: 803 DVSIGI----------KCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLF 852
Query: 1043 DGHPVPGSPFAVEGVLPPDPSKVCAYGPGLK--GGLVGTPAPFSIDTKGAGTGGL----- 1095
P SP V+ D SKV A GPGL G +G P F+++ K AG G L
Sbjct: 853 ADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFS 912
Query: 1096 GLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDP 1155
GLT +G ++ D+ D + V Y P + G +N+ + IP SPF + P D
Sbjct: 913 GLT-KGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDL 971
Query: 1156 SKVRASGPGLERGKVGEAATFTVDCSEAG-EAELTIEIL--SDAGVKAEVLIHNNADGTY 1212
SK++ SG G E+ VG+ FTV AG + ++ +I+ S A V +V AD +
Sbjct: 972 SKIKVSGLG-EKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSV 1030
Query: 1213 HITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGVEPHGVLREVTTE 1272
+ + P G Y + + Y G PVP P + S VK GPG++ G
Sbjct: 1031 -VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQ--GGSAGSPAR 1087
Query: 1273 FTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDE 1332
FT+D + TGG +T V P A+ + DNGDGT V Y E G + + +L+ +
Sbjct: 1088 FTIDTKG-AGTGGLGLT--VEGPCEAQLECL--DNGDGTCSVSYVPTEPGDYNINILFAD 1142
Query: 1333 VAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAI--EGP 1390
+P SPF+ V D ++V+ GPGLE + +F V+ AG+ L + I E
Sbjct: 1143 THIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAG 1202
Query: 1391 SEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSG 1450
A++ +D+ DG+ T+ YIP PG Y V I +GG+P+P P ++ V+ VD V+C G
Sbjct: 1203 LPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYG 1262
Query: 1451 PGL-GAGVRARVPQTFTVDC---SQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYT 1506
PG+ G GV F+VD +Q G ++ V P+G V+D GDG + V YT
Sbjct: 1263 PGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYT 1322
Query: 1507 PATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDA 1566
P +G ++V V Y VP SPF++ V D S+VR GPG+ + + P +FT++
Sbjct: 1323 PYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSG--TTNKPNKFTVET 1380
Query: 1567 RDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPF 1626
R AG G L + + P K + DN DG+ +V Y+P +G Y++ + YGG ++P SPF
Sbjct: 1381 RGAGTGGLGLAVEGPS--EAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPF 1438
Query: 1627 RIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPD 1686
++ DASK V G GL + ++ VD AG + V P
Sbjct: 1439 KVPVHDVTDASK----VKCSGPGLSPGM---VRANLPQSFQVDTSKAGVAPLQVKVQGPK 1491
Query: 1687 GAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLATEEPVVPVEPME 1746
G VDVV+N DGT + Y G Y I++ +G E +P SPF V V+P
Sbjct: 1492 GLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKV-----KVLPTHDAS 1546
Query: 1747 SMLR----------PFNLVIPFAVQ-----KGELTGEVRMPSGKTARPNITDNKDGTITV 1791
+ P +L + F + +G L ++ P GK + +I DN DGT TV
Sbjct: 1547 KVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTV 1606
Query: 1792 RYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRH-------VSAYGPGLSHGM---- 1840
Y P G + + IKY G+ IP SP + V A+ + VS G GL G+
Sbjct: 1607 AYVPDVTGRYTILIKYGGDEIPFSP--YRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTI 1664
Query: 1841 -VNKPATFTIVTKDAGEGGLSLAVEGP--SKAEITCKDNKDGTCTVSYLPTAPGDYSIIV 1897
+ + T+ TK AG+G ++ V P S+ ++ +N+DGT + Y PG Y I V
Sbjct: 1665 QIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICV 1724
Query: 1898 RFDDKHIPGSPF-TAKITGDD-----SMRTSQLN-------------------VGTSTDV 1932
RF +H+P SPF + GD +R+ QL VG +
Sbjct: 1725 RFGGEHVPNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLD 1784
Query: 1933 SLKITESDL--------SQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSV 1984
+ DL ++T +R PSG + + + + + P E G H + +
Sbjct: 1785 VTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDI 1844
Query: 1985 RKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLS 2044
R H+ SP + V + + V +G GL+ G + A F V+T++AG GGL L+
Sbjct: 1845 RYDNMHIPGSPLQFYV---DYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLA 1901
Query: 2045 IEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKES 2104
IEGPSK +I+C D +DGTC V+Y P PG Y I +K+ ++HVPGSPFT +VTG+ M+ S
Sbjct: 1902 IEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMS 1961
Query: 2105 ITRRRQAPSIATIGSTCDLNL----KIP------------------GNWFQMVSAQERLT 2142
+ A I S DL+L +P G F E L
Sbjct: 1962 HLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLV 2021
Query: 2143 RTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPAVFGDFLGRERLGSFG 2202
H + IS++ G+ R VRV G F +F+ R +G
Sbjct: 2022 HVKKNGQHVASSPIPVVISQSEIGDASR-VRVSGQGLHEGHTFEP--AEFIIDTRDAGYG 2078
Query: 2203 SITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQ 2262
++ EG + T + ED V + P E G + + +K+ Q
Sbjct: 2079 GLSLSIEGPSKVDINTEDL---------------EDGTCRVTYCPTEPGNYIINIKFADQ 2123
Query: 2263 HVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVA----GVPAEFSIWTREAGAGGLSIAV 2318
HVPGSPF V GEG +V+ T R + G + S+ E ++ V
Sbjct: 2124 HVPGSPFSVKV--TGEG---RVKESITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQV 2178
Query: 2319 EGPS----KAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSD- 2373
PS +AEI E C + +V E G + VS+K+ +H+P SPF V L +
Sbjct: 2179 TSPSGKTHEAEIV-EGENHTYC-IRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEG 2236
Query: 2374 DARRLTVTSLQETGLKVNQPASFAVQLNGA-RGVIDARVHTPSGAVEECYVSELDSDKHT 2432
A ++ + PA F++ A G + V PS A E +
Sbjct: 2237 GAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKA--EISFEDRKDGSCG 2294
Query: 2433 IRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSE 2492
+ ++ E G + + VKFN HIP SPF + V S +GD ++ G +
Sbjct: 2295 VAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVA--SPSGDARRLTVSSLQESGLKVNQPAS 2352
Query: 2493 FIVNTLNAGSGALSVTIDGPSKVQLDCREC---PEGHVVTYTPMAPGNYLIAIKYGGPQH 2549
F V +LN GA+ + PS +C + + V + P G YLI +K+ G H
Sbjct: 2353 FAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNG-TH 2410
Query: 2550 IVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVTRG 2609
I GSPFK +V P GH D V G
Sbjct: 2411 IPGSPFKIRVGEP----GH------------------------------GGDPGLVSAYG 2436
Query: 2610 PGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGP---KTPCEEVYVKHMGNRVYNVTYTVK 2666
GL G F V+ S AG + V + GP K C+E Y VTYT
Sbjct: 2437 AGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQEC------PEGYRVTYTPM 2490
Query: 2667 EKGDYILIVKWGDE-SVPGSPFKVKV 2691
G Y++ +K+G + GSPFK KV
Sbjct: 2491 APGSYLISIKYGGPYHIGGSPFKAKV 2516
>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
Length = 2639
Score = 3311 bits (8586), Expect = 0.0
Identities = 1674/2655 (63%), Positives = 1989/2655 (74%), Gaps = 120/2655 (4%)
Query: 3 NNSGYSDAGLGLGDETD----EMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLT 58
+ +G S AG G D EMP+TEKDLAEDAPWKKIQQNTFTRWCNEHLKCV KR+
Sbjct: 6 SRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIA 65
Query: 59 DLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSID 118
+LQ DLSDGLRLIALLEVLSQK+M+RK + RP FRQM+LENVSVALEFL+RE IKLVSID
Sbjct: 66 NLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSID 125
Query: 119 SKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPI 178
SKAIVDGNLKLILGLIWTLILHYSISMPMW++E+DE+A+KQTPKQRLLGWIQNK+PQLPI
Sbjct: 126 SKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPI 185
Query: 179 TNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPE 238
TNF+RDWQ G+ALGALVD+CAPGLCPDW++WD ++PV NAREAMQQADDWLG+PQVI PE
Sbjct: 186 TNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPE 245
Query: 239 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHF 298
EIVDPNVDEHSVMTYLSQFPKAKLKPGAP+R K LNPKKA AYGPGIEP GN V + A F
Sbjct: 246 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPK-LNPKKARAYGPGIEPTGNMVKKRAEF 304
Query: 299 TVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQN 358
TV+T AG GEVLVY+EDP GH EEAKV NNDK+RT++V YVP+V G HKVTVLFAGQ+
Sbjct: 305 TVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQH 364
Query: 359 IERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQ 418
I +SPFEV V + GDA+KV+A+GPGLEP GN+ANK TYF+I+TAGAGTG+V VVI DP
Sbjct: 365 IAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPM 424
Query: 419 GRRDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACR 478
G++ TVE LE +GDST+RC+Y+P MEG HTVHV FAG PI RSP+ V V +ACNP+ACR
Sbjct: 425 GQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACR 484
Query: 479 ASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYY 538
A GRGLQPKGVRVKE ADFKV+TKGAGSGELKVTVKGPKG EE VK ++ GDGV+ EYY
Sbjct: 485 AVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKG-EERVKQKDLGDGVYGFEYY 543
Query: 539 PVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIG 598
P+VPG Y+VTITWGG I RSPFEV+V E G QKVRAWGPGLE G VGKSADFVVEAIG
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 599 TEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHI 658
+VGTLGFS+EGPSQAKIECDDKGDGSCDVRYWP E GEYAVHV+C+ EDIR SPF+A I
Sbjct: 604 DDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADI 663
Query: 659 LPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKV 718
AP D PD+VKA GPGLE TG V+KPAEFT+DA+ GK L++ QD +GCP++ V
Sbjct: 664 RDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEALV 723
Query: 719 IPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTG 778
NG+GT+ CSYVP KP+KHT ++SWGGV++P SPFRVNVG GSHP +VKVYGPGV KTG
Sbjct: 724 KDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTG 783
Query: 779 LKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGA 838
LKA+EPTYFTVDC+EAGQGDVSIGIKCAPGVVGPAEADIDFDII+NDNDTFTVKYTP GA
Sbjct: 784 LKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGA 843
Query: 839 GRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAG 898
G YTIMVLFA+Q P SP +KV+PSHDASKVKAEGPGL+RTGVE+GKPTHFTV K AG
Sbjct: 844 GSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG 903
Query: 899 KAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVV 958
K KLDVQF+G KG+ VRD +IID+HD +YTVKYT VQQG + V VTYGGDP+PKSPF V
Sbjct: 904 KGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSV 963
Query: 959 NVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPG 1018
V+P LDLSKIKV GL KV VG++Q F+V ++GAGGQG++ ++ PS +PCK+EPG
Sbjct: 964 AVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPG 1023
Query: 1019 GGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVG 1078
GA+ VR++P EEGPY+V++TYDG PVPGSPF +E V P PSKV A+GPGL+GG G
Sbjct: 1024 LGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAG 1083
Query: 1079 TPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEA 1138
+PA F+IDTKGAGTGGLGLTVEGPCEA++EC DNGDG+C+VSY+PTEPG+Y INILFA+
Sbjct: 1084 SPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADT 1143
Query: 1139 HIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGV 1198
HIPGSPFKA + P FD SKV+ SGPGLER GE F VDCS AG AELTIEI S+AG+
Sbjct: 1144 HIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGL 1203
Query: 1199 KAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGP 1258
AEV I ++ DGT+ ITY P PG YT+TIKYGG PVP FP+++ V+PAVDTSGV+ GP
Sbjct: 1204 PAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGP 1263
Query: 1259 GVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTA 1318
G+E GV RE TTEF+VDAR+LT TGG HV ARV NPSG T+TYV D GDG Y+V+YT
Sbjct: 1264 GIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTP 1323
Query: 1319 YEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGA 1378
YEEG+H V+V YD VP SPF+V VTEGCDP+RVR GPG++ G NK N+FTVETRGA
Sbjct: 1324 YEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGA 1383
Query: 1379 GTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVK 1438
GTGGLGLA+EGPSEAKMSC DNKDGSC+VEYIP+ G Y +N+T+GG +PGSPF+VPV
Sbjct: 1384 GTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVH 1443
Query: 1439 DVVDPGKVKCSGPGLGAG-VRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNG 1497
DV D KVKCSGPGL G VRA +PQ+F VD S+AG APLQV V GP G+ EPV+V DN
Sbjct: 1444 DVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNA 1503
Query: 1498 DGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPAS 1557
DGT TV+Y P+ +GPY+++V Y D+EVPRSPFK+KVLP HDASKV+ASGPGLN +G+PAS
Sbjct: 1504 DGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPAS 1563
Query: 1558 LPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYG 1617
LPVEFTIDA+DAGEGLL VQI DPEGKPKK +I+DN DGTYTV+Y+PD++GRYTI IKYG
Sbjct: 1564 LPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYG 1623
Query: 1618 GDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGK 1677
GDEIP+SP+R+ A+PTGDASKC VT GA +GP IQIG+ETVITVD KAAG+GK
Sbjct: 1624 GDEIPFSPYRVRAVPTGDASKCTVT--------GAGIGPTIQIGEETVITVDTKAAGKGK 1675
Query: 1678 VTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVL---- 1733
VTCTV TPDG+E+DVDVVEN DGTFDI+YTAP+PGKYVI +RFGGEH+PNSPF V
Sbjct: 1676 VTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAG 1735
Query: 1734 ----------------------------ATEEPVVPVEPME-SMLRPFNLVIPFAVQKGE 1764
A E P+V V ++ + LRPF+LVIPF ++KGE
Sbjct: 1736 DQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGE 1795
Query: 1765 LTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAI 1824
+TGEVRMPSGK A+P ITDNKDGT+TVRYAP+E GLH+M I+YD HIPGSPLQFYVD +
Sbjct: 1796 ITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYV 1855
Query: 1825 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVS 1884
N HV+AYGPGL+HG+VNKPATFT+ TKDAGEGGLSLA+EGPSKAEI+C DN+DGTC+VS
Sbjct: 1856 NCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVS 1915
Query: 1885 YLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQL 1944
YLP PGDYSI+V+++++H+PGSPFTA++TGDDSMR S L VG++ D+ + I+E+DLS L
Sbjct: 1916 YLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLL 1975
Query: 1945 TASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSE 2004
TA++ PSG EEPCLLKRL N H+GISF PKE GEH+V V+K+G+HV +SP +++ SE
Sbjct: 1976 TATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSE 2035
Query: 2005 IGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCK 2064
IGDAS+VRV G+GL EGHTF+ AEFI+DTR+AGYGGL LSIEGPSKVDIN ED+EDGTC+
Sbjct: 2036 IGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCR 2095
Query: 2065 VTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLN 2124
VTYCPTEPG YIINIKFAD+HVPGSPF+VKVTGEGR+KESITRRR+APS+A +GS CDL+
Sbjct: 2096 VTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHCDLS 2155
Query: 2125 LKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGET-KREVRVEESTQ-VGG 2182
LKIP Q ++AQ T + T + E V V+ Q V G
Sbjct: 2156 LKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPG 2215
Query: 2183 DPFPAVFGDF----LGRERLGSFGSITRQQEG----------EASSQDMTAQVTSPSGKV 2228
PF G + R G G + R + G EA + + V PS K
Sbjct: 2216 SPFQFTVGPLGEGGAHKVRAGGPG-LERAEAGVPAEFSIWTREAGAGGLAIAVEGPS-KA 2273
Query: 2229 EAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGG 2288
E + + +D + V +V QE G + V+VK+ +H+P SPF V G A ++
Sbjct: 2274 EIS-FEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVAS-PSGDARRLTVSS 2331
Query: 2289 TGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKA--EIAFEDRKDGSCGVSYVVQEPG 2346
PA F++ + G + V PS A E + V ++ +E G
Sbjct: 2332 LQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENG 2390
Query: 2347 DYEVSIKFNDEHIPDSPFVVPVA--SLSDDARRLTVTSLQETGLKVNQPASFAVQL-NGA 2403
Y + +KFN HIP SPF + V D ++ G PA F V N
Sbjct: 2391 VYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAG 2450
Query: 2404 RGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGA-HIPGSPFKIR 2462
G + + PS +C + + + + + P G + I +K+ G HI GSPFK +
Sbjct: 2451 AGALSVTIDGPSKVKMDC---QECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAK 2507
Query: 2463 V-----------GEQS--------------QAGDPG-------LVSAYGPGLEGGTTGVS 2490
V E S Q G PG V A G GL G
Sbjct: 2508 VTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQK 2567
Query: 2491 SEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHV------VTYTPMAPGNYLIAIKY 2544
S F V+ AG+ L V + GP + C E HV V+Y G Y + +K+
Sbjct: 2568 SSFTVDCSKAGNNMLLVGVHGP---RTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKW 2624
Query: 2545 GGPQHIVGSPFKAKV 2559
G +HI GSP++ V
Sbjct: 2625 -GDEHIPGSPYRVVV 2638
Score = 1589 bits (4114), Expect = 0.0
Identities = 963/2439 (39%), Positives = 1345/2439 (55%), Gaps = 205/2439 (8%)
Query: 377 KVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTF 436
K A GPG+EP GN+ K F + T AG G+V V + DP G ++ +V + + TF
Sbjct: 283 KARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTF 342
Query: 437 RCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEAC-NPNACRASGRGLQPKGVRVKEVA 495
Y P + G H V V FAG I +SPF V+V ++ + + A G GL+P G +
Sbjct: 343 SVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTT 402
Query: 496 DFKVFTKGAGSGELKVTVKGP---KGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWG 552
F++FT GAG+GE++V ++ P KGT EP ++ GD + C Y P + G + V +T+
Sbjct: 403 YFEIFTAGAGTGEVEVVIQDPMGQKGTVEP-QLEARGDSTYRCSYQPTMEGVHTVHVTFA 461
Query: 553 GYAIPRSPFEVQVSPEAGVQKVRAWGPGLETG--QVGKSADFVVEAIGTEVGTLGFSIEG 610
G IPRSP+ V V RA G GL+ +V ++ADF V G G L +++G
Sbjct: 462 GVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKG 521
Query: 611 PS-QAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDK 669
P + +++ D GDG Y+P PG Y V + ++I SPF + +C K
Sbjct: 522 PKGEERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKV---GTECGNQK 578
Query: 670 VKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCS 729
V+A+GPGLE G +V K A+F ++A G L + I+ GDG+
Sbjct: 579 VRAWGPGLE--GGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECD--DKGDGSCDVR 634
Query: 730 YVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGS---HPERVKVYGPGVEKTGLKANEPTY 786
Y P + ++ + + ++ SPF ++ + HP+RVK GPG+EKTG+ N+P
Sbjct: 635 YWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAE 694
Query: 787 FTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVL 846
FTVD G+ + + ++ G P EA + N N T++ Y P ++T MV
Sbjct: 695 FTVDAKHGGKAPLRVQVQDNEGC--PVEALVK----DNGNGTYSCSYVPRKPVKHTAMVS 748
Query: 847 FANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQF 906
+ IP SPF + V +KVK GPG+ +TG++ +PT+FTV AG+ + +
Sbjct: 749 WGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAGQGDVSIGI 808
Query: 907 ------AGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
G A+ ++ DF+II N + ++TVKYT G+ + V + P SP V V
Sbjct: 809 KCAPGVVGPAEADI--DFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKV 866
Query: 961 APPLDLSKIKVQG---LNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEP 1017
P D SK+K +G + V +G+ F+VN + AG +G+LDV+ + ++ ++
Sbjct: 867 EPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG-KGKLDVQFSGLTKGDAVRDVDI 925
Query: 1018 GGGAE-AQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGL 1076
+ V+Y P ++GP V++TY G P+P SPF+V D SK+ G G K
Sbjct: 926 IDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVD- 984
Query: 1077 VGTPAPFSIDTKGAG-TGGLGLTVEGPCEAKIECQDN---GDGSCAVSYLPTEPGEYTIN 1132
VG F++ +KGAG G + + GP A + C+ G + V +LP E G Y +
Sbjct: 985 VGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSVVRFLPREEGPYEVE 1044
Query: 1133 ILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEI 1192
+ + +PGSPF PSKV+A GPGL+ G G A FT+D AG L + +
Sbjct: 1045 VTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTV 1104
Query: 1193 LSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSG 1252
+ E L +N DGT ++Y P PG Y I I + +P P + HV P D S
Sbjct: 1105 EGPCEAQLECL--DNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASK 1162
Query: 1253 VKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTY 1312
VK SGPG+E EV +F VD S G +T + + +G + Y+ D+GDGT+
Sbjct: 1163 VKCSGPGLE-RATAGEVG-QFQVDCSS---AGSAELTIEICSEAGLPAEVYIQDHGDGTH 1217
Query: 1313 RVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEG-GLVNKAN-R 1370
+ Y G + V + Y VP P ++ V D + V+ +GPG+EG G+ +A
Sbjct: 1218 TITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTE 1277
Query: 1371 FTVETRG-AGTGG--LGLAIEGPSE--AKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGG 1425
F+V+ R TGG + + PS + +D DG VEY P+ G + V++T+ G
Sbjct: 1278 FSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTPYEEGLHSVDVTYDG 1337
Query: 1426 RPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPT 1485
P+P SPF+VPV + DP +V+ GPG+ +G + P FTV+ AG L +AV GP+
Sbjct: 1338 SPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNK-PNKFTVETRGAGTGGLGLAVEGPS 1396
Query: 1486 GVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRAS 1545
+ DN DG+ +V Y P G Y++ V Y +VP SPFK+ V DASKV+ S
Sbjct: 1397 EAK--MSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCS 1454
Query: 1546 GPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPD 1605
GPGL+ + A+LP F +D AG L V++ P+G + ++ DN DGT TV+Y+P
Sbjct: 1455 GPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPS 1514
Query: 1606 MSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETV 1665
G Y+I++ YG +E+P SPF++ LPT DASK V G GL P
Sbjct: 1515 REGPYSISVLYGDEEVPRSPFKVKVLPTHDASK----VKASGPGLNTTGVPA---SLPVE 1567
Query: 1666 ITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHI 1725
T+DAK AGEG + ++ P+G + +NHDGT+ + Y G+Y I I++GG+ I
Sbjct: 1568 FTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEI 1627
Query: 1726 PNSPFHVLAT----------------------EEPVVPVEPMESMLRPFNLVIPFAVQKG 1763
P SP+ V A EE V+ V+ A KG
Sbjct: 1628 PFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTK-------------AAGKG 1674
Query: 1764 ELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDA 1823
++T V P G ++ +N+DGT + Y + G + + +++ G H+P SP Q V A
Sbjct: 1675 KVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQ--VTA 1732
Query: 1824 INSRHVSAYGP---------------------------GLSHGMVNKPATFTIV---TKD 1853
+ S P G++ V F +V T
Sbjct: 1733 LAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIK 1792
Query: 1854 AGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKI 1913
GE + + A+ T DNKDGT TV Y P+ G + + +R+D+ HIPGSP +
Sbjct: 1793 KGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV 1852
Query: 1914 TGDDSMRTSQLNVGTSTDVSLK-----ITESDLSQ--LTASIRAPSGNEEPCLLKRLPNR 1966
+ + G + V K + D + L+ +I PS E C + +
Sbjct: 1853 DYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQ--DG 1910
Query: 1967 HIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQV 2026
+S+ P G++ + V+ + +HV SPF V + S ++V
Sbjct: 1911 TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGS----------A 1960
Query: 2027 AEFIVDTRNAGYGGLGLSIEGPSKVDINC--EDMEDGTCKVTYCPTEPGTYIINIKFADK 2084
A+ ++ L ++ PS + C + + +G +++ P E G +++++K +
Sbjct: 1961 ADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQ 2020
Query: 2085 HVPGSPFTV-------------KVTGEGRMKESITRRRQAPSIATIGSTCDLNLKIPGNW 2131
HV SP V +V+G+G + + L+L I G
Sbjct: 2021 HVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGP- 2079
Query: 2132 FQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA-VFG 2190
++ + T R T G ++ + V G PF V G
Sbjct: 2080 ----------SKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQ-HVPGSPFSVKVTG 2128
Query: 2191 DFLGRERLGSFGSITRQQEG-----------------EASSQDMTAQVTSPSGKVEAAEI 2233
+ +E SITR++ E S QDMTAQVTSPSGK AEI
Sbjct: 2129 EGRVKE------SITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEI 2182
Query: 2234 VEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLER 2293
VEGE+ Y +RFVP EMG HTV+VKY+GQHVPGSPFQFTVGPLGEGGAHKVRAGG GLER
Sbjct: 2183 VEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLER 2242
Query: 2294 GVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIK 2353
AGVPAEFSIWTREAGAGGL+IAVEGPSKAEI+FEDRKDGSCGV+YVVQEPGDYEVS+K
Sbjct: 2243 AEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVK 2302
Query: 2354 FNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHT 2413
FN+EHIPDSPFVVPVAS S DARRLTV+SLQE+GLKVNQPASFAV LNGA+G IDA+VH+
Sbjct: 2303 FNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHS 2362
Query: 2414 PSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPG 2473
PSGA+EECYV+E+D DK+ +RFIP ENGV+ IDVKFNG HIPGSPFKIRVGE GDPG
Sbjct: 2363 PSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPG 2422
Query: 2474 LVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPM 2533
LVSAYG GLEGG TG +EF+VNT NAG+GALSVTIDGPSKV++DC+ECPEG+ VTYTPM
Sbjct: 2423 LVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPM 2482
Query: 2534 APGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYS 2593
APG+YLI+IKYGGP HI GSPFKAKVTGPRL HSLHETS+V V+++TK++ + +
Sbjct: 2483 APGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCA--PQHG 2540
Query: 2594 SIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKH 2653
+ +DASKVV +G GLS+A+VGQK+SFTVDCSKAG NM++VGVHGP+TPCEE+ VKH
Sbjct: 2541 APGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKH 2600
Query: 2654 MGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP 2692
+G+R+Y+V+Y +K+KG+Y L+VKWGDE +PGSP++V VP
Sbjct: 2601 VGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP 2639
Score = 905 bits (2340), Expect = 0.0
Identities = 725/2356 (30%), Positives = 1063/2356 (45%), Gaps = 264/2356 (11%)
Query: 473 NPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDG- 531
NP RA G G++P G VK+ A+F V T+ AG GE+ V V+ P G +E KV D
Sbjct: 280 NPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKN 339
Query: 532 -VFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQVSPEAG-VQKVRAWGPGLE-TGQVG- 587
F Y P V G + VT+ + G I +SPFEV V G KV A GPGLE +G +
Sbjct: 340 RTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIAN 399
Query: 588 KSADFVVEAIGTEVGTLGFSIEGPSQAK----IECDDKGDGSCDVRYWPTEPGEYAVHVI 643
K+ F + G G + I+ P K + + +GD + Y PT G + VHV
Sbjct: 400 KTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVT 459
Query: 644 CDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLK 703
I SP+ + A C P +A G GL+P G V + A+F + + AG G+LK
Sbjct: 460 FAGVPIPRSPYTVTVGQA---CNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELK 516
Query: 704 LYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSH 763
+ + G +K GDG + Y P P + + I+WGG N+ +SPF V VG
Sbjct: 517 VTVKGPKG-EERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECG 575
Query: 764 PERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIK 823
++V+ +GPG+E G + F V+ G + ++ GP++A I+ D
Sbjct: 576 NQKVRAWGPGLE--GGVVGKSADFVVEAIGDDVGTLGFSVE------GPSQAKIECD--D 625
Query: 824 NDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKV-DPSHD--ASKVKAEGPGLNRT 880
+ + V+Y P AG Y + VL +++I SPF + D D +VKA GPGL +T
Sbjct: 626 KGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKT 685
Query: 881 GVEVGKPTHFTVLTKGAGKAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNM 940
GV V KP FTV K GKA L VQ V + + DN + +Y+ Y +
Sbjct: 686 GVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPV--EALVKDNGNGTYSCSYVPRKPVKH 743
Query: 941 AVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQG---LNSKVAVGQEQAFSVNTRGAGGQG 997
V++GG +P SPF VNV +K+KV G + + + F+V+ AG QG
Sbjct: 744 TAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAG-QG 802
Query: 998 QLDVRMTSPSRRPIPCKLEPG--GGAEAQ-------------AVRYMPPEEGPYKVDITY 1042
+ + + K PG G AEA V+Y P G Y + + +
Sbjct: 803 DVSIGI----------KCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLF 852
Query: 1043 DGHPVPGSPFAVEGVLPPDPSKVCAYGPGLK--GGLVGTPAPFSIDTKGAGTGGL----- 1095
P SP V+ D SKV A GPGL G +G P F+++ K AG G L
Sbjct: 853 ADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFS 912
Query: 1096 GLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDP 1155
GLT +G ++ D+ D + V Y P + G +N+ + IP SPF + P D
Sbjct: 913 GLT-KGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDL 971
Query: 1156 SKVRASGPGLERGKVGEAATFTVDCSEAG-EAELTIEIL--SDAGVKAEVLIHNNADGTY 1212
SK++ SG G E+ VG+ FTV AG + ++ +I+ S A V +V AD +
Sbjct: 972 SKIKVSGLG-EKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSV 1030
Query: 1213 HITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGVEPHGVLREVTTE 1272
+ + P G Y + + Y G PVP P + S VK GPG++ G
Sbjct: 1031 -VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQ--GGSAGSPAR 1087
Query: 1273 FTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDE 1332
FT+D + TGG +T V P A+ + DNGDGT V Y E G + + +L+ +
Sbjct: 1088 FTIDTKG-AGTGGLGLT--VEGPCEAQLECL--DNGDGTCSVSYVPTEPGDYNINILFAD 1142
Query: 1333 VAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAI--EGP 1390
+P SPF+ V D ++V+ GPGLE + +F V+ AG+ L + I E
Sbjct: 1143 THIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAG 1202
Query: 1391 SEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSG 1450
A++ +D+ DG+ T+ YIP PG Y V I +GG+P+P P ++ V+ VD V+C G
Sbjct: 1203 LPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYG 1262
Query: 1451 PGL-GAGVRARVPQTFTVDC---SQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYT 1506
PG+ G GV F+VD +Q G ++ V P+G V+D GDG + V YT
Sbjct: 1263 PGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYT 1322
Query: 1507 PATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDA 1566
P +G ++V V Y VP SPF++ V D S+VR GPG+ + + P +FT++
Sbjct: 1323 PYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSG--TTNKPNKFTVET 1380
Query: 1567 RDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPF 1626
R AG G L + + P K + DN DG+ +V Y+P +G Y++ + YGG ++P SPF
Sbjct: 1381 RGAGTGGLGLAVEGPS--EAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPF 1438
Query: 1627 RIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPD 1686
++ DASK V G GL + ++ VD AG + V P
Sbjct: 1439 KVPVHDVTDASK----VKCSGPGLSPGM---VRANLPQSFQVDTSKAGVAPLQVKVQGPK 1491
Query: 1687 GAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLATEEPVVPVEPME 1746
G VDVV+N DGT + Y G Y I++ +G E +P SPF V V+P
Sbjct: 1492 GLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKV-----KVLPTHDAS 1546
Query: 1747 SMLR----------PFNLVIPFAVQ-----KGELTGEVRMPSGKTARPNITDNKDGTITV 1791
+ P +L + F + +G L ++ P GK + +I DN DGT TV
Sbjct: 1547 KVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTV 1606
Query: 1792 RYAPTEKGLHQMGIKYDGNHIPGSPLQFY-VDAINSRHVSAYGPGLSHGM-VNKPATFTI 1849
Y P G + + IKY G+ IP SP + V ++ + G G+ + + + T+
Sbjct: 1607 AYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITV 1666
Query: 1850 VTKDAGEGGLSLAVEGP--SKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGS 1907
TK AG+G ++ V P S+ ++ +N+DGT + Y PG Y I VRF +H+P S
Sbjct: 1667 DTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNS 1726
Query: 1908 PF-TAKITGDD-----SMRTSQLN-------------------VGTSTDVSLKITESDL- 1941
PF + GD +R+ QL VG + + DL
Sbjct: 1727 PFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLV 1786
Query: 1942 -------SQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNS 1994
++T +R PSG + + + + + P E G H + +R H+ S
Sbjct: 1787 IPFTIKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGS 1846
Query: 1995 PFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDIN 2054
P + V + + V +G GL+ G + A F V+T++AG GGL L+IEGPSK +I+
Sbjct: 1847 PLQFYV---DYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEIS 1903
Query: 2055 CEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSI 2114
C D +DGTC V+Y P PG Y I +K+ ++HVPGSPFT +VTG+ M+ S + A I
Sbjct: 1904 CTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADI 1963
Query: 2115 ATIGSTCDLNL----KIP------------------GNWFQMVSAQERLTRTFTRSSHTY 2152
S DL+L +P G F E L H
Sbjct: 1964 PINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVA 2023
Query: 2153 TRTERTEISKTRGGETKREVRVEESTQVGGDPFPAVFGDFLGRERLGSFGSITRQQEGEA 2212
+ IS++ G+ R VRV G F +F+ R +G ++ EG +
Sbjct: 2024 SSPIPVVISQSEIGDASR-VRVSGQGLHEGHTFEP--AEFIIDTRDAGYGGLSLSIEGPS 2080
Query: 2213 SSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFT 2272
T + ED V + P E G + + +K+ QHVPGSPF
Sbjct: 2081 KVDINTEDL---------------EDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVK 2125
Query: 2273 VGPLGEGGAHKVRAGGTGLERGVA----GVPAEFSIWTREAGAGGLSIAVEGPS----KA 2324
V GEG +V+ T R + G + S+ E ++ V PS +A
Sbjct: 2126 V--TGEG---RVKESITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEA 2180
Query: 2325 EIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSD-DARRLTVTSL 2383
EI E C + +V E G + VS+K+ +H+P SPF V L + A ++
Sbjct: 2181 EIV-EGENHTYC-IRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGP 2238
Query: 2384 QETGLKVNQPASFAVQLNGA-RGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGV 2442
+ PA F++ A G + V PS A E + + ++ E G
Sbjct: 2239 GLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKA--EISFEDRKDGSCGVAYVVQEPGD 2296
Query: 2443 HSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGS 2502
+ + VKFN HIP SPF + V S +GD ++ G + F V +LN
Sbjct: 2297 YEVSVKFNEEHIPDSPFVVPVA--SPSGDARRLTVSSLQESGLKVNQPASFAV-SLNGAK 2353
Query: 2503 GALSVTIDGPSKVQLDCREC---PEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKV 2559
GA+ + PS +C + + V + P G YLI +K+ G HI GSPFK +V
Sbjct: 2354 GAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNG-THIPGSPFKIRV 2412
Query: 2560 TGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQ 2619
P GH D V G GL G
Sbjct: 2413 GEP----GH------------------------------GGDPGLVSAYGAGLEGGVTGN 2438
Query: 2620 KNSFTVDCSKAGTNMMMVGVHGP---KTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVK 2676
F V+ S AG + V + GP K C+E Y VTYT G Y++ +K
Sbjct: 2439 PAEFVVNTSNAGAGALSVTIDGPSKVKMDCQEC------PEGYRVTYTPMAPGSYLISIK 2492
Query: 2677 WGDE-SVPGSPFKVKV 2691
+G + GSPFK KV
Sbjct: 2493 YGGPYHIGGSPFKAKV 2508
>gi|105990514 filamin B, beta (actin binding protein 278) [Homo
sapiens]
Length = 2602
Score = 3190 bits (8272), Expect = 0.0
Identities = 1611/2637 (61%), Positives = 1947/2637 (73%), Gaps = 134/2637 (5%)
Query: 21 MPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQK 80
MP TEKDLAEDAPWKKIQQNTFTRWCNEHLKCV KR+ +LQ DLSDGLRLIALLEVLSQK
Sbjct: 1 MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQK 60
Query: 81 RMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILH 140
RMYRK+H RP FRQM+LENVSVALEFL+RE IKLVSIDSKAIVDGNLKLILGL+WTLILH
Sbjct: 61 RMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILH 120
Query: 141 YSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITNFNRDWQDGKALGALVDNCAP 200
YSISMP+WEDE D+DA+KQTPKQRLLGWIQNK+P LPITNFN++WQDGKALGALVD+CAP
Sbjct: 121 YSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAP 180
Query: 201 GLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKA 260
GLCPDWE+WDP +PV+NAREAMQQADDWLGVPQVI PEEI+ P+VDEHSVMTYLSQFPKA
Sbjct: 181 GLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKA 240
Query: 261 KLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGH 320
KLKPGAP++ K LNPKKA AYG GIEP GN V QPA FTV T+ AG G+V+V++EDPEG+
Sbjct: 241 KLKPGAPLKPK-LNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGN 299
Query: 321 TEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSA 380
EEA+V P++DK++TY+V Y+PKV GLHKVTVLFAGQ+I +SPFEV+V A GDA+KV+A
Sbjct: 300 KEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTA 359
Query: 381 RGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTY 440
+GPGLE VGN+ANKPTYFDIYTAGAG GD+ V + DPQG+ +TVE+ +EDKG+ +RC Y
Sbjct: 360 KGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGK-NTVELLVEDKGNQVYRCVY 418
Query: 441 RPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVF 500
+P GPH V + FAG I +SPF V V EACNPNACRASGRGLQPKGVR++E DFKV
Sbjct: 419 KPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVD 478
Query: 501 TKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSP 560
TK AGSGEL VT+KGPKG EE VK ++ DGV+ EYYP PG+Y + ITWGG+ IP+SP
Sbjct: 479 TKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSP 538
Query: 561 FEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDD 620
FEVQV PEAG+QKVRAWGPGL G VG+SADFVVE+IG+EVG+LGF+IEGPSQAKIE +D
Sbjct: 539 FEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYND 598
Query: 621 KGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPT 680
+ DGSCDV+YWP EPGEYAVH++CDDEDI+DSP++A I PA PD V+A+GPGLE +
Sbjct: 599 QNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKS 658
Query: 681 GCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTI 740
GCIV+ AEFT+D + AGK LK++AQD +G IDI++ DGT+ CSY P K IKHTI
Sbjct: 659 GCIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTI 718
Query: 741 IISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVS 800
+ WGGVN+P SP+RVN+G+GSHP++VKV+GPGVE++GLKANEPT+FTVDC+EAG+GDVS
Sbjct: 719 AVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVS 778
Query: 801 IGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIK 860
+GIKC V+ E D+DFDII N NDTFTVKY PP AGRYTI VLFA+QEIPASPF +K
Sbjct: 779 VGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVK 838
Query: 861 VDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQFAGTAKGEVVRDFEI 920
VDPSHDASKVKAEGPGL++ GVE GKPTHFTV TKGAGKA L+VQF G+ V+D +I
Sbjct: 839 VDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDI 898
Query: 921 IDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAV 980
IDN+DYS+TVKYT QQGNM V VTYGGDP+PKSPF V VA PLDLSKIK+ GL ++V V
Sbjct: 899 IDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEV 958
Query: 981 GQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDI 1040
G++Q F+V+TRGAGGQG+LDV + SPSR+ +PC + P G E +++P EEG Y VD+
Sbjct: 959 GKDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDV 1018
Query: 1041 TYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTVE 1100
TYDGHPVPGSP+ VE LPPDPSKV A+GPGL+GGLVG PA F+IDTKGAGTGGLGLTVE
Sbjct: 1019 TYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVE 1078
Query: 1101 GPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRA 1160
GPCEAKIEC DNGDG+C+VSYLPT+PGEY +NILF E HIPGSPFKA I FDPSKV A
Sbjct: 1079 GPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVA 1138
Query: 1161 SGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAF 1220
SGPGLE GKVGEA +VDCSEAG L +E +SD+G KAEV I NN DGTY +TY P
Sbjct: 1139 SGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLT 1198
Query: 1221 PGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGVEPHGVLREVTTEFTVDARSL 1280
G YT+T+KYGG VP FP RV V+PAVDTS +KV GPG+E V RE TT+FTVD+R L
Sbjct: 1199 AGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPL 1258
Query: 1281 TATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPF 1340
T GG+H+ A + NPSGA T+ +VTDN DGTY+V+YT +E+G+H+VEV YD+V +P SPF
Sbjct: 1259 TQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPF 1318
Query: 1341 RVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDN 1400
+V VTEGC P+RV+A GPGL+ NK N FTV TRGAG GGLG+ +EGPSE+K++C+DN
Sbjct: 1319 KVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDN 1378
Query: 1401 KDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRAR 1460
KDGSC+ EYIPF PGDYDVNIT+GG IPGSPFRVPVKDVVDP KVK +GPGLG+GVRAR
Sbjct: 1379 KDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRAR 1438
Query: 1461 VPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYA 1520
V Q+FTVD S+AG APL+V VLGP G+ EPV V DNGDGTHTV YTP+ +GPY V+VKYA
Sbjct: 1439 VLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYA 1498
Query: 1521 DQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILD 1580
D+E+PRSPFK+KVLP +DASKV ASGPGL++ G+PASLPV+F IDARDAGEGLL VQI D
Sbjct: 1499 DEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITD 1558
Query: 1581 PEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCL 1640
EGKPK+A + DN DGTY V+Y+PD +GRY I + YGGD+IP SP+RI A TGDASKCL
Sbjct: 1559 QEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCL 1618
Query: 1641 VTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDG 1700
T G + ++ G+E VDAK AG+GKVTCTV TPDG E + DV+EN DG
Sbjct: 1619 AT--------GPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDG 1670
Query: 1701 TFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLA------------------------TE 1736
T+DI+YTA +PG YVI +RFGG IPNSPF V+A TE
Sbjct: 1671 TYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGFRPWVTE 1730
Query: 1737 EPVVPVEPMESM-LRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAP 1795
E VPV M + +PF+LVIPFAV+KGE+TGEV MPSGKTA P I DNKDGT+TVRYAP
Sbjct: 1731 EAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAP 1790
Query: 1796 TEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAG 1855
TE GLH+M IKY G+HIP SPLQFYV+ NS VSAYGPGL +G+ NK ATFTIVT+DAG
Sbjct: 1791 TEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAG 1850
Query: 1856 EGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITG 1915
EGGL LA+EGPSKAEI+C DNKDGTCTV+YLPT PGDYSI+V+++DKHIPGSPFTAKIT
Sbjct: 1851 EGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKIT- 1909
Query: 1916 DDSMRTSQLNVGTSTDVSLKITESDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPK 1975
DDS R SQ+ +G++ D L I+E+DLS LTASI+APSG +EPCLLKRLPN HIGISF P+
Sbjct: 1910 DDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPR 1969
Query: 1976 EVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRN 2035
EVGEH+VS++K+G HV NSP I+V SEIGDA + +V+G+GLSEG TF++++FIVDTR+
Sbjct: 1970 EVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRD 2029
Query: 2036 AGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKV 2095
AGYGG+ L++EGPSKVDI ED+EDGTCKV+Y PT PG YI++ KFAD+HVPGSPFTVK+
Sbjct: 2030 AGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKI 2089
Query: 2096 TGEGRMKESITRRRQAPSIATIGSTCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRT 2155
+GEGR+KESITR +APS+AT+GS CDLNLKIP +++ + + S T
Sbjct: 2090 SGEGRVKESITRTSRAPSVATVGSICDLNLKIP-----EINSSDMSAHVTSPSGRV---T 2141
Query: 2156 ERTEISKTRGGETKREVRVE----------ESTQVGGDPFPAVFGDF----LGRERLGSF 2201
E + + R V E V G PF G + R G
Sbjct: 2142 EAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGP 2201
Query: 2202 GSITRQQEG----------EASSQDMTAQVTSPSGKVEAAEIV--EGEDSAYSVRFVPQE 2249
G + R + G EA + ++ V PS AEI + ++ + V ++ QE
Sbjct: 2202 G-LERGEAGVPAEFSIWTREAGAGGLSIAVEGPS----KAEITFDDHKNGSCGVSYIAQE 2256
Query: 2250 MGPHTVAVKYRGQHVPGSPFQF-TVGPLGEGGAHKVRA-GGTGLERGVAGVPAEFSIWTR 2307
G + V++K+ +H+P SP+ + P + V + +GL+ PA F+I
Sbjct: 2257 PGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLK---VNQPASFAIRLN 2313
Query: 2308 EAGAGGLSIAVEGPSKA--EIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFV 2365
A G + V PS A E + + V ++ E G + + +KFN H+ SPF
Sbjct: 2314 GA-KGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFK 2372
Query: 2366 VPVASLSDDARRLTVTSLQETGLKVN----QPASFAVQLNGARGVIDARVHTPSGAVEEC 2421
V V A + S TGL+ Q F G + + PS +C
Sbjct: 2373 VRVGE-PGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDC 2431
Query: 2422 YVSELDSDKHTIRFIPHENGVHSIDVKFNGA-HIPGSPFKIRVGEQ-------------- 2466
+ + + + + P G + I VK+ G HI GSPFK +V Q
Sbjct: 2432 ---QETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSI 2488
Query: 2467 ------------------SQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVT 2508
+ D V++ G GL G S F+V+ AGS L +
Sbjct: 2489 LVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIG 2548
Query: 2509 IDGPSKVQLDCRECPEGHV------VTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKV 2559
+ GP+ C E HV VTY G+Y++A+K+ G +HI GSPF V
Sbjct: 2549 VHGPT---TPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKW-GEEHIPGSPFHVTV 2601
Score = 1531 bits (3965), Expect = 0.0
Identities = 951/2416 (39%), Positives = 1330/2416 (55%), Gaps = 169/2416 (6%)
Query: 377 KVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTF 436
K A G G+EP GN+ +P F + T AG GDV V + DP+G ++ +V + + T+
Sbjct: 256 KARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAQVTPDSDKNKTY 315
Query: 437 RCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEAC-NPNACRASGRGLQPKGVRVKEVA 495
Y P + G H V V FAG I++SPF V V +A + + A G GL+ G +
Sbjct: 316 SVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPT 375
Query: 496 DFKVFTKGAGSGELKVTVKGPKGTEE-PVKVREAGDGVFECEYYPVVPGKYVVTITWGGY 554
F ++T GAG G++ V V+ P+G + V + G+ V+ C Y P+ PG +VV I + G
Sbjct: 376 YFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGD 435
Query: 555 AIPRSPFEVQVSPEAGVQKVRAWGPGLETG--QVGKSADFVVEAIGTEVGTLGFSIEGPS 612
IP+SPF VQV RA G GL+ ++ ++ DF V+ G LG +++GP
Sbjct: 436 TIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPK 495
Query: 613 --QAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKV 670
+ ++ D DG Y+P+ PG Y++ + I SPF + P+ KV
Sbjct: 496 GLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQV---GPEAGMQKV 552
Query: 671 KAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSY 730
+A+GPGL G IV + A+F +++ + G L + I+ DG+ Y
Sbjct: 553 RAWGPGLH--GGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYN--DQNDGSCDVKY 608
Query: 731 VPTKPIKHTIIISWGGVNVPKSPFRVNVGE---GSHPERVKVYGPGVEKTGLKANEPTYF 787
P +P ++ + I ++ SP+ + G +P+ V+ YGPG+EK+G N F
Sbjct: 609 WPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEF 668
Query: 788 TVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLF 847
TVD +AG+ + I + G ID + + T+ YTP A ++TI V++
Sbjct: 669 TVDPKDAGKAPLKIFAQDGEG------QRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVW 722
Query: 848 ANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQFA 907
IP SP+ + + KVK GPG+ R+G++ +PTHFTV AG+ + V
Sbjct: 723 GGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIK 782
Query: 908 GTAK----GEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPP 963
A+ E DF+II N + ++TVKY G + V + +P SPF V V P
Sbjct: 783 CDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPS 842
Query: 964 LDLSKIKVQGLN-SKVAV--GQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG 1020
D SK+K +G SK V G+ F+V T+GAG + L+V+ SP L+
Sbjct: 843 HDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAG-KAPLNVQFNSPLPGDAVKDLDIIDN 901
Query: 1021 AE-AQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGL-VG 1078
+ + V+Y P ++G +V +TY G P+P SPF V P D SK+ G L+ + VG
Sbjct: 902 YDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNG--LENRVEVG 959
Query: 1079 TPAPFSIDTKGAG-TGGLGLTVEGPCEAKIEC---QDNGDGSCAVSYLPTEPGEYTINIL 1134
F++DT+GAG G L +T+ P + C G + ++P E G Y +++
Sbjct: 960 KDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVT 1019
Query: 1135 FAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILS 1194
+ +PGSP+ DPSKV+A GPGLE G VG+ A FT+D AG L + +
Sbjct: 1020 YDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTV-- 1077
Query: 1195 DAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVK 1254
+ +A++ +N DGT ++Y P PG Y + I + +P P + ++ D S V
Sbjct: 1078 EGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVV 1137
Query: 1255 VSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRV 1314
SGPG+E HG + E +VD + G + ++ SG K + + +N DGTY V
Sbjct: 1138 ASGPGLE-HGKVGEAGL-LSVDC---SEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAV 1192
Query: 1315 QYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNK--ANRFT 1372
Y G++ + + Y VP P RV V D +R++ FGPG+EG V + FT
Sbjct: 1193 TYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFT 1252
Query: 1373 VETRG---AGTGGLGLAIEGPSEAKMSC--KDNKDGSCTVEYIPFTPGDYDVNITFGGRP 1427
V++R G + I PS A C DN DG+ VEY PF G + V +T+ P
Sbjct: 1253 VDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVP 1312
Query: 1428 IPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGV 1487
IP SPF+V V + P +V+ GPGL + P FTV AG L + V GP+
Sbjct: 1313 IPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNK-PNVFTVVTRGAGIGGLGITVEGPS-- 1369
Query: 1488 AEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGP 1547
+ RDN DG+ + Y P G Y V + Y +P SPF++ V D SKV+ +GP
Sbjct: 1370 ESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGP 1429
Query: 1548 GLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMS 1607
GL SG+ A + FT+D+ AG L V++L P G + N+ DNGDGT+TV+Y P
Sbjct: 1430 GLG-SGVRARVLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQE 1488
Query: 1608 GRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVIT 1667
G Y +++KY +EIP SPF++ LPT DASK V+ G GL + P
Sbjct: 1489 GPYMVSVKYADEEIPRSPFKVKVLPTYDASK----VTASGPGLSSYGVPA---SLPVDFA 1541
Query: 1668 VDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPN 1727
+DA+ AGEG + ++ +G V +N DGT+ + Y + G+Y+I + +GG+ IP
Sbjct: 1542 IDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPL 1601
Query: 1728 SPFHVLATE----EPVVPVEPMESMLRPFNLVIPFAVQ-----KGELTGEVRMPSGKTAR 1778
SP+ + AT+ + P + + F V KG++T V P G A
Sbjct: 1602 SPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAE 1661
Query: 1779 PNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFY-----VDAINSRHVSAYG 1833
++ +N+DGT + Y + G + + +++ G IP SP V A+ V+A
Sbjct: 1662 ADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACP 1721
Query: 1834 PGLS--------------HGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCK--DNK 1877
PG +G+ KP ++ +G ++ V PS T + DNK
Sbjct: 1722 PGFRPWVTEEAYVPVSDMNGLGFKPFDL-VIPFAVRKGEITGEVHMPSGKTATPEIVDNK 1780
Query: 1878 DGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLK-- 1935
DGT TV Y PT G + + +++ HIP SP + +S S G V+ K
Sbjct: 1781 DGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTA 1840
Query: 1936 ---ITESDLSQ--LTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKH 1990
I D + L +I PS E C+ + + +++ P G++ + V+ + KH
Sbjct: 1841 TFTIVTEDAGEGGLDLAIEGPSKAEISCIDNK--DGTCTVTYLPTLPGDYSILVKYNDKH 1898
Query: 1991 VTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSK 2050
+ SPF +K+ + S+ A+F++D L SI+ PS
Sbjct: 1899 IPGSPF-----------TAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSG 1947
Query: 2051 VDINC--EDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVT------------ 2096
D C + + + +++ P E G ++++IK HV SP ++ V
Sbjct: 1948 RDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKV 2007
Query: 2097 -----GEGR---MKESITRRRQAP----SIATIG-STCDLNLK------IPGNWFQMVSA 2137
EGR M + I R A S+A G S D+ + ++F V
Sbjct: 2008 YGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPG 2067
Query: 2138 QERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEES-TQVGGDPFPAVFGDFLGRE 2196
++ F H +IS E RV+ES T+ P A G
Sbjct: 2068 VYIVSTKFA-DEHVPGSPFTVKISG--------EGRVKESITRTSRAPSVATVGSICD-- 2116
Query: 2197 RLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVA 2256
+ E +S DM+A VTSPSG+V AEIV +++ VRFVPQEMG HTV+
Sbjct: 2117 --------LNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVS 2168
Query: 2257 VKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSI 2316
VKYRGQHV GSPFQFTVGPLGEGGAHKVRAGG GLERG AGVPAEFSIWTREAGAGGLSI
Sbjct: 2169 VKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSI 2228
Query: 2317 AVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDAR 2376
AVEGPSKAEI F+D K+GSCGVSY+ QEPG+YEVSIKFNDEHIP+SP++VPV + SDDAR
Sbjct: 2229 AVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDAR 2288
Query: 2377 RLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFI 2436
RLTV SLQE+GLKVNQPASFA++LNGA+G IDA+VH+PSGAVEEC+VSEL+ DK+ +RFI
Sbjct: 2289 RLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFI 2348
Query: 2437 PHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVN 2496
PHENGVH+IDVKFNG+H+ GSPFK+RVGE QAG+P LVSAYG GLEGGTTG+ SEF +N
Sbjct: 2349 PHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFIN 2408
Query: 2497 TLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFK 2556
T AG G LSVTI+GPSKV++DC+E PEG+ V YTPMAPGNYLI++KYGGP HIVGSPFK
Sbjct: 2409 TTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFK 2468
Query: 2557 AKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAF 2616
AKVTG RL S +ETS++LVE+VT+SS+ + YS+IPK SSDASKV ++G GLS+AF
Sbjct: 2469 AKVTGQRLVSPGSANETSSILVESVTRSSTE--TCYSAIPKASSDASKVTSKGAGLSKAF 2526
Query: 2617 VGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVK 2676
VGQK+SF VDCSKAG+NM+++GVHGP TPCEEV +KH+GN+ YNVTY VKE+GDY+L VK
Sbjct: 2527 VGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVK 2586
Query: 2677 WGDESVPGSPFKVKVP 2692
WG+E +PGSPF V VP
Sbjct: 2587 WGEEHIPGSPFHVTVP 2602
Score = 416 bits (1070), Expect = e-115
Identities = 361/1291 (27%), Positives = 557/1291 (43%), Gaps = 147/1291 (11%)
Query: 1525 PRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGK 1584
P +P K K+ P K RA G G+ +G P +FT+D AG+G + V + DPEG
Sbjct: 244 PGAPLKPKLNP----KKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGN 299
Query: 1585 PKKANIRDNGDG--TYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHA-LPTGDASKCLV 1641
++A + + D TY+V YLP ++G + +T+ + G I SPF + GDASK
Sbjct: 300 KEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASK--- 356
Query: 1642 TVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAE-LDVDVVENHDG 1700
V+ G GL A + T + AG G + V P G +++ V + +
Sbjct: 357 -VTAKGPGLEAVGNIA---NKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQ 412
Query: 1701 TFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLATEEPVVP---------VEPMESMLRP 1751
+ Y +PG +V+ I F G+ IP SPF V+ E P ++P +R
Sbjct: 413 VYRCVYKPMQPGPHVVKIFFAGDTIPKSPF-VVQVGEACNPNACRASGRGLQPKGVRIRE 471
Query: 1752 FN--LVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDG 1809
V A GEL ++ P G D DG Y P+ G + + I + G
Sbjct: 472 TTDFKVDTKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGG 531
Query: 1810 NHIPGSPLQFYVDA-INSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSK 1868
+HIP SP + V + V A+GPGL G+V + A F + + + G L A+EGPS+
Sbjct: 532 HHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQ 591
Query: 1869 AEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKI---TGD--------- 1916
A+I D DG+C V Y P PG+Y++ + DD+ I SP+ A I TG
Sbjct: 592 AKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAY 651
Query: 1917 -DSMRTSQLNVGTSTDVSLKITESDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPK 1975
+ S V + ++ ++ + L + G +K + S+TP
Sbjct: 652 GPGLEKSGCIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPV 711
Query: 1976 EVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEG--HTFQVAEFIVDT 2033
+ +H ++V G ++ +SP+++ +G KV+V+G G+ + F VD
Sbjct: 712 KAIKHTIAVVWGGVNIPHSPYRVNIGQGS--HPQKVKVFGPGVERSGLKANEPTHFTVDC 769
Query: 2034 RNAGYGGLGLSI--------EGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKH 2085
AG G + + I E VD + + T V Y P G Y I + FA +
Sbjct: 770 TEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQE 829
Query: 2086 VPGSPFTVKVT-----------GEGRMKESITRRRQAP-SIATIGS-----TCDLNLKIP 2128
+P SPF VKV G G K + + ++ T G+ N +P
Sbjct: 830 IPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLP 889
Query: 2129 GNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPAV 2188
G+ + + + + T +T T+ ++ T GG+ + D
Sbjct: 890 GDAVKDLDIIDNYDYSHT-VKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIK 948
Query: 2189 FGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEI--VEGEDSAYSVRFV 2246
R +G T G + + SPS KV + V G +++ + +F+
Sbjct: 949 LNGLENRVEVGKDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENS-TAKFI 1007
Query: 2247 PQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWT 2306
P+E G + V V Y G VPGSP+ TV KV+A G GLE G+ G PAEF+I T
Sbjct: 1008 PREEGLYAVDVTYDGHPVPGSPY--TVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDT 1065
Query: 2307 REAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVV 2366
+ AG GGL + VEGP +A+I D DG+C VSY+ +PG+Y V+I F + HIP SPF
Sbjct: 1066 KGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKA 1125
Query: 2367 PVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGA-RGVIDARVHTPSGAVEECYVSE 2425
+ D ++ + E G KV + +V + A G + + SG E +
Sbjct: 1126 DIEMPFDPSKVVASGPGLEHG-KVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQN 1184
Query: 2426 LDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGG 2485
+ + ++P G++++ +K+ G +P P +++V A D + +GPG+EG
Sbjct: 1185 NKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKV---EPAVDTSRIKVFGPGIEGK 1241
Query: 2486 TT--GVSSEFIVNT---LNAGSGALSVTIDGPSKVQLDC--RECPEG-HVVTYTPMAPGN 2537
+++F V++ G + I PS +C + +G + V YTP G
Sbjct: 1242 DVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGL 1301
Query: 2538 YLIAIKYGGPQHIVGSPFKAKVT-----------GPRLSGGHSLHETSTVLVE------- 2579
+++ + Y I SPFK VT GP L + +V
Sbjct: 1302 HVVEVTYDDVP-IPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGG 1360
Query: 2580 ---TVTKSSSSR---------GSSYSSIPKFSSDASKVVTRG------------------ 2609
TV S S+ S IP D +T G
Sbjct: 1361 LGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVD 1420
Query: 2610 --------PGLSQAFVGQ-KNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYN 2660
PGL + SFTVD SKAG + V V GP+ E V V G+ +
Sbjct: 1421 PSKVKIAGPGLGSGVRARVLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHT 1480
Query: 2661 VTYTVKEKGDYILIVKWGDESVPGSPFKVKV 2691
VTYT ++G Y++ VK+ DE +P SPFKVKV
Sbjct: 1481 VTYTPSQEGPYMVSVKYADEEIPRSPFKVKV 1511
>gi|239755812 PREDICTED: similar to spectrin, beta, non-erythrocytic
2 [Homo sapiens]
Length = 158
Score = 192 bits (489), Expect = 3e-48
Identities = 93/120 (77%), Positives = 106/120 (88%)
Query: 82 MYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHY 141
MY K+H RP FRQM+L+NVSVALEFL+R+ IKLVSIDSKA VDGNLKLILGL+WTLIL Y
Sbjct: 1 MYLKYHQRPTFRQMQLKNVSVALEFLDRDSIKLVSIDSKATVDGNLKLILGLVWTLILRY 60
Query: 142 SISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITNFNRDWQDGKALGALVDNCAPG 201
SIS P+ EDE D+DA+KQ KQRLLGWIQNKVP LPITNF+++WQD KAL ALVD+CAPG
Sbjct: 61 SISTPVCEDEGDDDAKKQMRKQRLLGWIQNKVPYLPITNFSQNWQDSKALRALVDSCAPG 120
>gi|4557241 actinin, alpha 3 [Homo sapiens]
Length = 901
Score = 164 bits (416), Expect = 8e-40
Identities = 94/254 (37%), Positives = 151/254 (59%), Gaps = 21/254 (8%)
Query: 11 GLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRL 70
G G G+ ++ ++DL D W+K Q+ TFT WCN HL+ G ++ +++ D +GL+L
Sbjct: 20 GGGGGEYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKL 79
Query: 71 IALLEVLSQKRMYRKFHPRPNFRQM---KLENVSVALEFLEREHIKLVSIDSKAIVDGNL 127
+ LLEV+S +R+ PRP+ +M K+ NV+ AL+F+ + +KLVSI ++ IVDGNL
Sbjct: 80 MLLLEVISGERL-----PRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNL 134
Query: 128 KLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVP---QLPITNFNRD 184
K+ LG+IWT+IL ++I D + + K+ LL W Q K + + NF+
Sbjct: 135 KMTLGMIWTIILRFAI--------QDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTS 186
Query: 185 WQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVD-P 243
W+DG AL AL+ P L D+ + P+ N A + A+ +L +P+++ E+IV+ P
Sbjct: 187 WKDGLALCALIHRHRPDLI-DYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTP 245
Query: 244 NVDEHSVMTYLSQF 257
DE ++MTY+S F
Sbjct: 246 KPDEKAIMTYVSCF 259
>gi|12025678 actinin, alpha 4 [Homo sapiens]
Length = 911
Score = 160 bits (406), Expect = 1e-38
Identities = 94/262 (35%), Positives = 148/262 (56%), Gaps = 21/262 (8%)
Query: 6 GYSDAGLG------LGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTD 59
G S AG G +GD + ++DL D W+K Q+ TFT WCN HL+ G ++ +
Sbjct: 14 GPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIEN 73
Query: 60 LQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDS 119
+ D DGL+L+ LLEV+S +R+ + R R K+ NV+ AL+F+ + +KLVSI +
Sbjct: 74 IDEDFRDGLKLMLLLEVISGERLPKP--ERGKMRVHKINNVNKALDFIASKGVKLVSIGA 131
Query: 120 KAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQL 176
+ IVDGN K+ LG+IWT+IL ++I D + + K+ LL W Q K +
Sbjct: 132 EEIVDGNAKMTLGMIWTIILRFAI--------QDISVEETSAKEGLLLWCQRKTAPYKNV 183
Query: 177 PITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIA 236
+ NF+ W+DG A AL+ P L +++ + PV N A + A+ +L +P+++
Sbjct: 184 NVQNFHISWKDGLAFNALIHRHRPELI-EYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLD 242
Query: 237 PEEIVD-PNVDEHSVMTYLSQF 257
E+IV+ DE ++MTY+S F
Sbjct: 243 AEDIVNTARPDEKAIMTYVSSF 264
>gi|4501893 actinin, alpha 2 [Homo sapiens]
Length = 894
Score = 158 bits (399), Expect = 8e-38
Identities = 89/240 (37%), Positives = 145/240 (60%), Gaps = 21/240 (8%)
Query: 25 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYR 84
++DL D W+K Q+ TFT WCN HL+ G ++ +++ D +GL+L+ LLEV+S +R+
Sbjct: 27 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERL-- 84
Query: 85 KFHPRPNFRQM---KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHY 141
P+P+ +M K+ NV+ AL+++ + +KLVSI ++ IVDGN+K+ LG+IWT+IL +
Sbjct: 85 ---PKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRF 141
Query: 142 SISMPMWEDEDDEDARKQTPKQRLLGWIQNKVP---QLPITNFNRDWQDGKALGALVDNC 198
+I D + + K+ LL W Q K + I NF+ W+DG L AL+
Sbjct: 142 AI--------QDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRH 193
Query: 199 APGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVD-PNVDEHSVMTYLSQF 257
P L D+ + + P+ N AM+ A+ L +P+++ E+IV+ P DE ++MTY+S F
Sbjct: 194 RPDLI-DYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCF 252
>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
Length = 887
Score = 154 bits (388), Expect = 1e-36
Identities = 87/237 (36%), Positives = 137/237 (57%), Gaps = 15/237 (6%)
Query: 25 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYR 84
++DL D W+K Q+ TFT WCN HL+ G ++ +++ D DGL+L+ LLEV+S +R+ +
Sbjct: 20 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAK 79
Query: 85 KFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSIS 144
R R K+ NV+ AL+F+ + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I
Sbjct: 80 P--ERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI- 136
Query: 145 MPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPG 201
D + + K+ LL W Q K + I NF+ W+DG AL+ P
Sbjct: 137 -------QDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPE 189
Query: 202 LCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIV-DPNVDEHSVMTYLSQF 257
L D+ + P+ N A A+ +L +P+++ E+IV DE ++MTY+S F
Sbjct: 190 LI-DYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSF 245
>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
Length = 914
Score = 154 bits (388), Expect = 1e-36
Identities = 87/237 (36%), Positives = 137/237 (57%), Gaps = 15/237 (6%)
Query: 25 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYR 84
++DL D W+K Q+ TFT WCN HL+ G ++ +++ D DGL+L+ LLEV+S +R+ +
Sbjct: 20 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAK 79
Query: 85 KFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSIS 144
R R K+ NV+ AL+F+ + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I
Sbjct: 80 P--ERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI- 136
Query: 145 MPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPG 201
D + + K+ LL W Q K + I NF+ W+DG AL+ P
Sbjct: 137 -------QDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPE 189
Query: 202 LCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIV-DPNVDEHSVMTYLSQF 257
L D+ + P+ N A A+ +L +P+++ E+IV DE ++MTY+S F
Sbjct: 190 LI-DYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSF 245
>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
Length = 892
Score = 154 bits (388), Expect = 1e-36
Identities = 87/237 (36%), Positives = 137/237 (57%), Gaps = 15/237 (6%)
Query: 25 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYR 84
++DL D W+K Q+ TFT WCN HL+ G ++ +++ D DGL+L+ LLEV+S +R+ +
Sbjct: 20 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAK 79
Query: 85 KFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSIS 144
R R K+ NV+ AL+F+ + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I
Sbjct: 80 P--ERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI- 136
Query: 145 MPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPG 201
D + + K+ LL W Q K + I NF+ W+DG AL+ P
Sbjct: 137 -------QDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPE 189
Query: 202 LCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIV-DPNVDEHSVMTYLSQF 257
L D+ + P+ N A A+ +L +P+++ E+IV DE ++MTY+S F
Sbjct: 190 LI-DYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSF 245
>gi|67782321 spectrin beta isoform a [Homo sapiens]
Length = 2328
Score = 147 bits (371), Expect = 1e-34
Identities = 87/227 (38%), Positives = 129/227 (56%), Gaps = 14/227 (6%)
Query: 37 IQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMK 96
+Q+ TFT+W N HL V R+TDL +DL DG LI LLEVLS + + P+P +M+
Sbjct: 55 VQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEML-----PKPTKGKMR 109
Query: 97 ---LENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDD 153
LENV AL+FL+ + + L ++ S IVDGN +L+LGLIWT+IL + I + + ++
Sbjct: 110 IHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEG 169
Query: 154 EDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWD 210
+ R + K LL W Q K P + +TNF W+DG A AL+ P L D++
Sbjct: 170 RETR--SAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLI-DFDKLK 226
Query: 211 PNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQF 257
+ N A A+ LG+ ++ PE++ N DE S++TY+ F
Sbjct: 227 DSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAF 273
>gi|67782319 spectrin beta isoform b [Homo sapiens]
Length = 2137
Score = 147 bits (371), Expect = 1e-34
Identities = 87/227 (38%), Positives = 129/227 (56%), Gaps = 14/227 (6%)
Query: 37 IQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMK 96
+Q+ TFT+W N HL V R+TDL +DL DG LI LLEVLS + + P+P +M+
Sbjct: 55 VQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEML-----PKPTKGKMR 109
Query: 97 ---LENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDD 153
LENV AL+FL+ + + L ++ S IVDGN +L+LGLIWT+IL + I + + ++
Sbjct: 110 IHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEG 169
Query: 154 EDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWD 210
+ R + K LL W Q K P + +TNF W+DG A AL+ P L D++
Sbjct: 170 RETR--SAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLI-DFDKLK 226
Query: 211 PNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQF 257
+ N A A+ LG+ ++ PE++ N DE S++TY+ F
Sbjct: 227 DSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAF 273
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 147 bits (371), Expect = 1e-34
Identities = 93/235 (39%), Positives = 136/235 (57%), Gaps = 16/235 (6%)
Query: 26 KDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRK 85
K LA++ + +Q+ TFT+W N HL V R+TDL DL DG LI LLEVLS +R+
Sbjct: 46 KALADER--EAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERL--- 100
Query: 86 FHPRPNFRQMK---LENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYS 142
P+P +M+ LENV AL+FL+ + + L ++ S IVDGN +L LGLIWT+IL +
Sbjct: 101 --PKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQ 158
Query: 143 ISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCA 199
I E ED+++ K++ K LL W Q K P + I NF W+DG A AL+
Sbjct: 159 IQDISVETEDNKE--KKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHR 216
Query: 200 PGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYL 254
P L D++ + N + A A+ LG+ +++ PE+I + DE S++TY+
Sbjct: 217 PDLI-DFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYV 270
>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
sapiens]
Length = 2155
Score = 147 bits (370), Expect = 2e-34
Identities = 90/224 (40%), Positives = 130/224 (58%), Gaps = 14/224 (6%)
Query: 37 IQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMK 96
+Q+ TFT+W N HL V R+TDL DL DG LI LLEVLS +R+ P+P +M+
Sbjct: 42 VQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERL-----PKPTKGRMR 96
Query: 97 ---LENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDD 153
LENV AL+FL+ + + L ++ S IVDGN +L LGLIWT+IL + I E ED+
Sbjct: 97 IHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDN 156
Query: 154 EDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWD 210
++ K++ K LL W Q K P + I NF W+DG A AL+ P L D++
Sbjct: 157 KE--KKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLI-DFDKLK 213
Query: 211 PNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYL 254
+ N + A A+ LG+ +++ PE+I + DE S++TY+
Sbjct: 214 KSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYV 257
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 145 bits (365), Expect = 7e-34
Identities = 92/231 (39%), Positives = 132/231 (57%), Gaps = 16/231 (6%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL V K + DL DL DG LI+LLEVLS ++ R+ + R
Sbjct: 78 RVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPRE---KGRMRFH 134
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
+L+NV +AL+FL++ +KLV+I + I DGN KL LGLIWT+ILH+ IS E +
Sbjct: 135 RLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGD- 193
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ K++LL W Q + TNF+ W DGK AL+ P L D E
Sbjct: 194 ---MSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLV-DMERVQIQ 249
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQ----FPK 259
EN +A + A+ LGV +++ E++ P+ DE SV+TY+S FPK
Sbjct: 250 SNRENLEQAFEVAER-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPK 299
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1
[Homo sapiens]
Length = 2564
Score = 143 bits (361), Expect = 2e-33
Identities = 90/238 (37%), Positives = 134/238 (56%), Gaps = 16/238 (6%)
Query: 26 KDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRK 85
K LA++ + +Q+ TFT+W N HL VG + DL DL DG L LLEVLS +++
Sbjct: 53 KALADER--EAVQKKTFTKWVNSHLARVGCHIGDLYVDLRDGFVLTRLLEVLSGEQL--- 107
Query: 86 FHPRPNFRQMK---LENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYS 142
PRP +M+ LENV AL+FL+ + + L ++ S IVDGN +L LGL+WT+IL +
Sbjct: 108 --PRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQ 165
Query: 143 ISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCA 199
I + E ED+ + R + K LL W Q K P++ I NF W+DG A AL+
Sbjct: 166 IQVIKIETEDNRETR--SAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHR 223
Query: 200 PGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQF 257
P L D+ + N + A + A+ LG+ +++ PE++ DE S++TY+ F
Sbjct: 224 PDLV-DFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSF 280
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 142 bits (359), Expect = 3e-33
Identities = 92/251 (36%), Positives = 137/251 (54%), Gaps = 20/251 (7%)
Query: 17 ETDEMPST-EKDLAEDAPWK--------KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDG 67
ET +P+T ++ LA P ++Q+ TFT+W N+HL + ++DL DL DG
Sbjct: 151 ETPVVPATTQRTLARPGPEPAPATDERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDG 210
Query: 68 LRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNL 127
LI+LLEVLS + R+ + R KL+NV +AL++L +KLV+I + I DGN
Sbjct: 211 HNLISLLEVLSGDSLPRE---KGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNP 267
Query: 128 KLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRD 184
KL LGLIWT+ILH+ IS + + + T K++LL W Q V L NF
Sbjct: 268 KLTLGLIWTIILHFQIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSS 323
Query: 185 WQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPN 244
W+DG+ A++ P L D +EN +A A+ LGV +++ PE++ P
Sbjct: 324 WRDGRLFNAIIHRHKP-LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQ 382
Query: 245 VDEHSVMTYLS 255
DE S++TY+S
Sbjct: 383 PDEKSIITYVS 393
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 142 bits (358), Expect = 4e-33
Identities = 90/250 (36%), Positives = 136/250 (54%), Gaps = 12/250 (4%)
Query: 10 AGLGLGDETDEMPSTEKDLAEDAPWK-KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGL 68
+G G G + E+ + A + ++Q+ TFT+W N+HL + ++DL DL DG
Sbjct: 42 SGGGAGSNGSVLDPAERAVIRIADERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGH 101
Query: 69 RLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLK 128
LI+LLEVLS + R+ + R KL+NV +AL++L +KLV+I + I DGN K
Sbjct: 102 NLISLLEVLSGDSLPRE---KGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPK 158
Query: 129 LILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDW 185
L LGLIWT+ILH+ IS + + + T K++LL W Q V L NF W
Sbjct: 159 LTLGLIWTIILHFQIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSW 214
Query: 186 QDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNV 245
+DG+ A++ P L D +EN +A A+ LGV +++ PE++ P
Sbjct: 215 RDGRLFNAIIHRHKP-LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 273
Query: 246 DEHSVMTYLS 255
DE S++TY+S
Sbjct: 274 DEKSIITYVS 283
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 42 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 98
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 99 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 154
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 155 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 213
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 214 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 256
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 46 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 102
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 103 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 158
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 159 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 217
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 218 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 260
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 42 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 98
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 99 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 154
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 155 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 213
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 214 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 256
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 10 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 66
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 67 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 122
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 123 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 181
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 182 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 224
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 20 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 76
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 77 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 132
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 133 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 191
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 192 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 234
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 28 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 84
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 85 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 140
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 141 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 199
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 200 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 242
>gi|169218211 PREDICTED: similar to plectin 1, partial [Homo
sapiens]
Length = 1369
Score = 139 bits (351), Expect = 3e-32
Identities = 91/251 (36%), Positives = 136/251 (54%), Gaps = 20/251 (7%)
Query: 17 ETDEMPST-EKDLAEDAPWK--------KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDG 67
ET +P+T ++ LA P ++Q+ T T+W N+HL + ++DL DL DG
Sbjct: 147 ETPVVPATTQRTLARPGPEPAPATDERDRVQKKTSTKWVNKHLIKAQRHISDLYEDLRDG 206
Query: 68 LRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNL 127
LI+LLEVLS + R+ + R KL+NV +AL++L +KLV+I + I DGN
Sbjct: 207 HNLISLLEVLSGDSLPRE---KGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNP 263
Query: 128 KLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRD 184
KL LGLIWT+ILH+ IS + + + T K++LL W Q V L NF
Sbjct: 264 KLTLGLIWTIILHFQIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSS 319
Query: 185 WQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPN 244
W+DG+ A++ P L D +EN +A A+ LGV +++ PE++ P
Sbjct: 320 WRDGRLFNAIIHRHKP-LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQ 378
Query: 245 VDEHSVMTYLS 255
DE S++TY+S
Sbjct: 379 PDEKSIITYVS 389
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 139 bits (349), Expect = 5e-32
Identities = 89/231 (38%), Positives = 128/231 (55%), Gaps = 16/231 (6%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
K+Q+ TFT+W N+HL V K + DL DL DG LI+LLEVLS + R+ + R
Sbjct: 64 KVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPRE---KGRMRFH 120
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
+L+NV +AL++L+R +KLV+I + I DGN KL LGLIWT+ILH+ IS E ++
Sbjct: 121 RLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESED- 179
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ K+RLL W Q + NF W+DGK A++ P L D
Sbjct: 180 ---MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLI-DMNTVAVQ 235
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQ----FPK 259
+ N A A+ +GV +++ PE++ + DE SV+TY+S FPK
Sbjct: 236 SNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 285
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 139 bits (349), Expect = 5e-32
Identities = 89/231 (38%), Positives = 128/231 (55%), Gaps = 16/231 (6%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
K+Q+ TFT+W N+HL V K + DL DL DG LI+LLEVLS + R+ + R
Sbjct: 75 KVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPRE---KGRMRFH 131
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
+L+NV +AL++L+R +KLV+I + I DGN KL LGLIWT+ILH+ IS E ++
Sbjct: 132 RLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESED- 190
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ K+RLL W Q + NF W+DGK A++ P L D
Sbjct: 191 ---MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLI-DMNTVAVQ 246
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQ----FPK 259
+ N A A+ +GV +++ PE++ + DE SV+TY+S FPK
Sbjct: 247 SNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 296
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 139 bits (349), Expect = 5e-32
Identities = 89/231 (38%), Positives = 128/231 (55%), Gaps = 16/231 (6%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
K+Q+ TFT+W N+HL V K + DL DL DG LI+LLEVLS + R+ + R
Sbjct: 213 KVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPRE---KGRMRFH 269
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
+L+NV +AL++L+R +KLV+I + I DGN KL LGLIWT+ILH+ IS E ++
Sbjct: 270 RLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESED- 328
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ K+RLL W Q + NF W+DGK A++ P L D
Sbjct: 329 ---MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLI-DMNTVAVQ 384
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQ----FPK 259
+ N A A+ +GV +++ PE++ + DE SV+TY+S FPK
Sbjct: 385 SNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 434
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 119,029,586
Number of Sequences: 37866
Number of extensions: 6468176
Number of successful extensions: 14916
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 10822
Number of HSP's gapped (non-prelim): 532
length of query: 2692
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2572
effective length of database: 13,703,598
effective search space: 35245654056
effective search space used: 35245654056
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.