Guide to the Human Genome
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Search of human proteins with 188528677

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|188528677 tRNA splicing endonuclease 15 isoform 2 [Homo
sapiens]
         (129 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|188528677 tRNA splicing endonuclease 15 isoform 2 [Homo sapiens]   273   4e-74
gi|24308390 tRNA splicing endonuclease 15 isoform 1 [Homo sapiens]    253   3e-68
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap...    35   0.021
gi|53829365 potassium channel tetramerisation domain containing ...    31   0.24 
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    29   0.90 
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    29   0.90 
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    29   0.90 
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    29   0.90 
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]               28   1.5  
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 28   1.5  
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]                   28   2.0  
gi|119395750 keratin 1 [Homo sapiens]                                  28   2.6  
gi|5174703 mitogen-activated protein kinase kinase kinase 7 inte...    28   2.6  
gi|41281798 mitogen-activated protein kinase kinase kinase 7 int...    28   2.6  
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi...    28   2.6  
gi|239753335 PREDICTED: hypothetical protein [Homo sapiens]            27   3.4  
gi|239751010 PREDICTED: hypothetical protein [Homo sapiens]            27   3.4  
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i...    27   3.4  
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s...    27   3.4  
gi|150378447 zinc and ring finger 3 [Homo sapiens]                     27   3.4  
gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I...    27   3.4  
gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I...    27   3.4  
gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]     27   3.4  
gi|223278393 protein phosphatase 1, regulatory (inhibitor) subun...    27   4.5  
gi|13899269 SRY-box 7 [Homo sapiens]                                   27   4.5  
gi|239757704 PREDICTED: hypothetical protein XP_002345526 [Homo ...    27   4.5  
gi|239752189 PREDICTED: hypothetical protein [Homo sapiens]            27   4.5  
gi|239746712 PREDICTED: hypothetical protein XP_002343817 [Homo ...    27   4.5  
gi|239743069 PREDICTED: hypothetical protein XP_002342750 [Homo ...    27   4.5  
gi|239508715 PREDICTED: hypothetical protein [Homo sapiens]            27   4.5  

>gi|188528677 tRNA splicing endonuclease 15 isoform 2 [Homo sapiens]
          Length = 129

 Score =  273 bits (697), Expect = 4e-74
 Identities = 129/129 (100%), Positives = 129/129 (100%)

Query: 1   MEERGDSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQV 60
           MEERGDSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQV
Sbjct: 1   MEERGDSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQV 60

Query: 61  YVAFLVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEGLQTVVPTPITASLSHNRIF 120
           YVAFLVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEGLQTVVPTPITASLSHNRIF
Sbjct: 61  YVAFLVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEGLQTVVPTPITASLSHNRIF 120

Query: 121 LLEDDIHVS 129
           LLEDDIHVS
Sbjct: 121 LLEDDIHVS 129


>gi|24308390 tRNA splicing endonuclease 15 isoform 1 [Homo sapiens]
          Length = 171

 Score =  253 bits (646), Expect = 3e-68
 Identities = 119/119 (100%), Positives = 119/119 (100%)

Query: 1   MEERGDSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQV 60
           MEERGDSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQV
Sbjct: 1   MEERGDSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQV 60

Query: 61  YVAFLVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEGLQTVVPTPITASLSHNRI 119
           YVAFLVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEGLQTVVPTPITASLSHNRI
Sbjct: 61  YVAFLVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEGLQTVVPTPITASLSHNRI 119


>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
          Length = 2365

 Score = 34.7 bits (78), Expect = 0.021
 Identities = 17/34 (50%), Positives = 20/34 (58%)

Query: 15   GLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLE 48
            GLGPGG  G G+     + APE AW GT  +Y E
Sbjct: 1453 GLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKE 1486


>gi|53829365 potassium channel tetramerisation domain containing 2
          [Homo sapiens]
          Length = 263

 Score = 31.2 bits (69), Expect = 0.24
 Identities = 15/35 (42%), Positives = 17/35 (48%)

Query: 11 PGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPK 45
          P  +GLG GG  G GDGGG     P     G  P+
Sbjct: 8  PAMAGLGGGGGSGVGDGGGPVRGPPSPRPAGPTPR 42


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 29.3 bits (64), Expect = 0.90
 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 1/54 (1%)

Query: 7   SEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQV 60
           +E   G SG GPGG  G G  GGA + A  DA +G   + L  ++      T V
Sbjct: 779 AEGAAGGSGGGPGGAEGGGVTGGARA-ALSDAELGRWAELLSPLDESRASITSV 831



 Score = 27.7 bits (60), Expect = 2.6
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%)

Query: 6   DSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHP 44
           D  P+PG SG    G    G G GA S +P+ A +G  P
Sbjct: 723 DPGPSPGTSG----GKAAAGAGAGASSRSPKQARLGELP 757


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 29.3 bits (64), Expect = 0.90
 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 1/54 (1%)

Query: 7    SEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQV 60
            +E   G SG GPGG  G G  GGA + A  DA +G   + L  ++      T V
Sbjct: 1048 AEGAAGGSGGGPGGAEGGGVTGGARA-ALSDAELGRWAELLSPLDESRASITSV 1100



 Score = 27.7 bits (60), Expect = 2.6
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%)

Query: 6    DSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHP 44
            D  P+PG SG    G    G G GA S +P+ A +G  P
Sbjct: 992  DPGPSPGTSG----GKAAAGAGAGASSRSPKQARLGELP 1026


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 29.3 bits (64), Expect = 0.90
 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 1/54 (1%)

Query: 7   SEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQV 60
           +E   G SG GPGG  G G  GGA + A  DA +G   + L  ++      T V
Sbjct: 740 AEGAAGGSGGGPGGAEGGGVTGGARA-ALSDAELGRWAELLSPLDESRASITSV 792



 Score = 27.7 bits (60), Expect = 2.6
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%)

Query: 6   DSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHP 44
           D  P+PG SG    G    G G GA S +P+ A +G  P
Sbjct: 684 DPGPSPGTSG----GKAAAGAGAGASSRSPKQARLGELP 718


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 29.3 bits (64), Expect = 0.90
 Identities = 12/22 (54%), Positives = 13/22 (59%)

Query: 22  RGFGDGGGAPSWAPEDAWMGTH 43
           RG G GGGAP+W P  A    H
Sbjct: 515 RGAGRGGGAPAWQPASAPPAPH 536


>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
          Length = 332

 Score = 28.5 bits (62), Expect = 1.5
 Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 8/41 (19%)

Query: 12 GCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMEL 52
          G +G G GG  G G GGG  S AP        P+ L M +L
Sbjct: 50 GGNGAGGGGAGGAGGGGGGGSRAP--------PEELSMFQL 82


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 28.5 bits (62), Expect = 1.5
 Identities = 13/25 (52%), Positives = 13/25 (52%), Gaps = 1/25 (4%)

Query: 15  GLGPGGVRGFGDGGGAPSWAPEDAW 39
           G G GG  G G  GG P W P  AW
Sbjct: 432 GGGSGGGGGVGGAGGGP-WGPAPAW 455



 Score = 25.8 bits (55), Expect = 9.9
 Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)

Query: 12  GCSGLGPGGVRGFGDG--GGAPSWAP 35
           G SG G GGV G G G  G AP+W P
Sbjct: 433 GGSG-GGGGVGGAGGGPWGPAPAWCP 457


>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
          Length = 284

 Score = 28.1 bits (61), Expect = 2.0
 Identities = 11/17 (64%), Positives = 12/17 (70%)

Query: 5  GDSEPTPGCSGLGPGGV 21
          G   P PG SG+GPGGV
Sbjct: 64 GSLAPLPGSSGVGPGGV 80


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 27.7 bits (60), Expect = 2.6
 Identities = 11/18 (61%), Positives = 12/18 (66%)

Query: 12  GCSGLGPGGVRGFGDGGG 29
           G  G+G GG  GFG GGG
Sbjct: 110 GGGGIGGGGFGGFGSGGG 127


>gi|5174703 mitogen-activated protein kinase kinase kinase 7
          interacting protein 1 isoform alpha [Homo sapiens]
          Length = 504

 Score = 27.7 bits (60), Expect = 2.6
 Identities = 14/36 (38%), Positives = 18/36 (50%), Gaps = 1/36 (2%)

Query: 6  DSEPTPGCSGLGPGGVRGFG-DGGGAPSWAPEDAWM 40
          D  P    SG+G    R +  DG G  S  PED+W+
Sbjct: 19 DDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWL 54


>gi|41281798 mitogen-activated protein kinase kinase kinase 7
          interacting protein 1 isoform beta [Homo sapiens]
          Length = 462

 Score = 27.7 bits (60), Expect = 2.6
 Identities = 14/36 (38%), Positives = 18/36 (50%), Gaps = 1/36 (2%)

Query: 6  DSEPTPGCSGLGPGGVRGFG-DGGGAPSWAPEDAWM 40
          D  P    SG+G    R +  DG G  S  PED+W+
Sbjct: 19 DDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWL 54


>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
           sapiens]
          Length = 1143

 Score = 27.7 bits (60), Expect = 2.6
 Identities = 12/37 (32%), Positives = 21/37 (56%)

Query: 65  LVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEG 101
           L ++ L+E+   + VNCV +P LQ + L    ++  G
Sbjct: 879 LSFVSLLETNKPYLVNCVRIPALQSLLLFSRSLDTNG 915


>gi|239753335 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 113

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 15/36 (41%), Positives = 17/36 (47%), Gaps = 1/36 (2%)

Query: 5   GDSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWM 40
           GD    P  +G  PGG RG G GG  P      AW+
Sbjct: 74  GDGGGLPRRAGAEPGG-RGGGSGGTMPGGRRAAAWL 108


>gi|239751010 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 220

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 14/34 (41%), Positives = 14/34 (41%)

Query: 11  PGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHP 44
           PG S    GG  G G GGGA  W       G  P
Sbjct: 81  PGDSSHSRGGRWGVGGGGGAALWRQRTVEAGCSP 114


>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
           isoform [Homo sapiens]
          Length = 302

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 18/35 (51%), Positives = 18/35 (51%), Gaps = 3/35 (8%)

Query: 4   RGDSEPTPGCSGLG--PGGVRGFGD-GGGAPSWAP 35
           RG   P  G SGLG   GG  G G  GGGAP   P
Sbjct: 92  RGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREP 126


>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
           sapiens]
          Length = 411

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 18/35 (51%), Positives = 18/35 (51%), Gaps = 3/35 (8%)

Query: 4   RGDSEPTPGCSGLG--PGGVRGFGD-GGGAPSWAP 35
           RG   P  G SGLG   GG  G G  GGGAP   P
Sbjct: 92  RGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREP 126


>gi|150378447 zinc and ring finger 3 [Homo sapiens]
          Length = 836

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 15/44 (34%), Positives = 18/44 (40%), Gaps = 5/44 (11%)

Query: 9   PTPGCSG-----LGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYL 47
           P+ G +G     LGP    G G  GG P         G HP +L
Sbjct: 623 PSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHL 666


>gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I
            subunit isoform b [Homo sapiens]
          Length = 2188

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 5/36 (13%)

Query: 10   TPGCSGLGPGGVRGFGDGGG-----APSWAPEDAWM 40
            +PG  G GPGG  G GD  G       S A E+ W+
Sbjct: 1733 SPGAPGRGPGGAGGGGDTEGGLCRRCYSPAQENLWL 1768


>gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I
            subunit isoform a [Homo sapiens]
          Length = 2223

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 5/36 (13%)

Query: 10   TPGCSGLGPGGVRGFGDGGG-----APSWAPEDAWM 40
            +PG  G GPGG  G GD  G       S A E+ W+
Sbjct: 1768 SPGAPGRGPGGAGGGGDTEGGLCRRCYSPAQENLWL 1803


>gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]
          Length = 651

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 7/66 (10%)

Query: 5   GDSEPTPG----CSGLGPGGVRGFGDGGGAP--SWAPEDAWMGTHPKYLEMMELDIGDAT 58
           G S P PG     SG G GG     +G GAP  + AP+D   G    +L  ++L +  A 
Sbjct: 412 GPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFL-ALDLTVPAAA 470

Query: 59  QVYVAF 64
            ++  F
Sbjct: 471 TIWAPF 476


>gi|223278393 protein phosphatase 1, regulatory (inhibitor)
          subunit 3G [Homo sapiens]
          Length = 358

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 12/24 (50%), Positives = 14/24 (58%)

Query: 21 VRGFGDGGGAPSWAPEDAWMGTHP 44
          V+G GDGGGA      DA +G  P
Sbjct: 35 VQGGGDGGGASETPSPDAQLGDRP 58


>gi|13899269 SRY-box 7 [Homo sapiens]
          Length = 388

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 22/66 (33%), Positives = 28/66 (42%), Gaps = 12/66 (18%)

Query: 2   EERGDSEP------TPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIG 55
           E+RG+  P        GC   GP G    G GGG PS    D +    P   EM  LD+ 
Sbjct: 160 EDRGEYSPGTALPSLRGCYHEGPAG----GGGGGTPS--SVDTYPYGLPTPPEMSPLDVL 213

Query: 56  DATQVY 61
           +  Q +
Sbjct: 214 EPEQTF 219


>gi|239757704 PREDICTED: hypothetical protein XP_002345526 [Homo
          sapiens]
          Length = 67

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 12/22 (54%), Positives = 13/22 (59%)

Query: 17 GPGGVRGFGDGGGAPSWAPEDA 38
          GPG   G GDGGGA    P+ A
Sbjct: 33 GPGPGSGDGDGGGAEQLPPQTA 54


>gi|239752189 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 67

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 12/22 (54%), Positives = 13/22 (59%)

Query: 17 GPGGVRGFGDGGGAPSWAPEDA 38
          GPG   G GDGGGA    P+ A
Sbjct: 33 GPGPGSGDGDGGGAEQLPPQTA 54


>gi|239746712 PREDICTED: hypothetical protein XP_002343817 [Homo
          sapiens]
          Length = 67

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 12/22 (54%), Positives = 13/22 (59%)

Query: 17 GPGGVRGFGDGGGAPSWAPEDA 38
          GPG   G GDGGGA    P+ A
Sbjct: 33 GPGPGSGDGDGGGAEQLPPQTA 54


>gi|239743069 PREDICTED: hypothetical protein XP_002342750 [Homo
          sapiens]
          Length = 231

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 14/32 (43%), Positives = 15/32 (46%), Gaps = 3/32 (9%)

Query: 3  ERGDSEPTPGCSGLGPGGVRGFGDGGGAPSWA 34
          E    EP P    + PGG  G G G GA  WA
Sbjct: 70 EEPPEEPAPA---IAPGGSGGGGGGCGAQHWA 98


>gi|239508715 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 231

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 14/32 (43%), Positives = 15/32 (46%), Gaps = 3/32 (9%)

Query: 3  ERGDSEPTPGCSGLGPGGVRGFGDGGGAPSWA 34
          E    EP P    + PGG  G G G GA  WA
Sbjct: 70 EEPPEEPAPA---IAPGGSGGGGGGCGAQHWA 98


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.139    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,314,469
Number of Sequences: 37866
Number of extensions: 317691
Number of successful extensions: 1648
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 1553
Number of HSP's gapped (non-prelim): 112
length of query: 129
length of database: 18,247,518
effective HSP length: 90
effective length of query: 39
effective length of database: 14,839,578
effective search space: 578743542
effective search space used: 578743542
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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