Guide to the Human Genome
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Search of human proteins with 188219579

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
         (587 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|188219579 ring finger protein 19B isoform b [Homo sapiens]        1215   0.0  
gi|188219577 ring finger protein 19B isoform a [Homo sapiens]        1198   0.0  
gi|35493801 ring finger protein 19 [Homo sapiens]                     722   0.0  
gi|35493782 ring finger protein 19 [Homo sapiens]                     722   0.0  
gi|38045938 ring finger protein 144 [Homo sapiens]                    113   4e-25
gi|50284696 IBR domain containing 2 [Homo sapiens]                    103   6e-22
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro...    99   1e-20
gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa...    93   6e-19
gi|5453557 ariadne homolog 2 [Homo sapiens]                            90   7e-18
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo...    89   1e-17
gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]            78   2e-14
gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]            78   2e-14
gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]            78   2e-14
gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]            78   2e-14
gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]             78   2e-14
gi|109150431 ring finger protein 31 [Homo sapiens]                     71   3e-12
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is...    69   1e-11
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ...    69   1e-11
gi|46370057 ring finger protein 216 isoform b [Homo sapiens]           62   1e-09
gi|46358403 ring finger protein 216 isoform a [Homo sapiens]           62   1e-09
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]       58   3e-08
gi|169790973 parkin isoform 3 [Homo sapiens]                           56   8e-08
gi|169790971 parkin isoform 2 [Homo sapiens]                           56   8e-08
gi|169790969 parkin isoform 1 [Homo sapiens]                           56   8e-08
gi|22749145 ring finger protein 217 [Homo sapiens]                     55   2e-07
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       50   4e-06
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]           50   6e-06
gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo ...    49   1e-05
gi|48255913 tripartite motif-containing 16 [Homo sapiens]              49   1e-05
gi|239753500 PREDICTED: hypothetical protein [Homo sapiens]            47   4e-05

>gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
          Length = 587

 Score = 1215 bits (3143), Expect = 0.0
 Identities = 587/587 (100%), Positives = 587/587 (100%)

Query: 1   MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA 60
           MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA
Sbjct: 1   MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA 60

Query: 61  AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP 120
           AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP
Sbjct: 61  AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP 120

Query: 121 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA 180
           LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA
Sbjct: 121 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA 180

Query: 181 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH 240
           DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH
Sbjct: 181 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH 240

Query: 241 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGS 300
           CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGS
Sbjct: 241 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGS 300

Query: 301 CNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGI 360
           CNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGI
Sbjct: 301 CNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGI 360

Query: 361 SLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSV 420
           SLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSV
Sbjct: 361 SLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSV 420

Query: 421 GIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPSI 480
           GIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPSI
Sbjct: 421 GIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPSI 480

Query: 481 GESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLEV 540
           GESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLEV
Sbjct: 481 GESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLEV 540

Query: 541 QADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRFSMIHA 587
           QADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRFSMIHA
Sbjct: 541 QADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRFSMIHA 587


>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
          Length = 732

 Score = 1198 bits (3100), Expect = 0.0
 Identities = 581/582 (99%), Positives = 581/582 (99%), Gaps = 1/582 (0%)

Query: 1   MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA 60
           MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA
Sbjct: 1   MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA 60

Query: 61  AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP 120
           AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP
Sbjct: 61  AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP 120

Query: 121 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA 180
           LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA
Sbjct: 121 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA 180

Query: 181 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH 240
           DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH
Sbjct: 181 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH 240

Query: 241 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGP-DDIKPCPRCSAYIIKMNDG 299
           CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGP DDIKPCPRCSAYIIKMNDG
Sbjct: 241 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDG 300

Query: 300 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG 359
           SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG
Sbjct: 301 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG 360

Query: 360 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS 419
           ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS
Sbjct: 361 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS 420

Query: 420 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS 479
           VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS
Sbjct: 421 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS 480

Query: 480 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE 539
           IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE
Sbjct: 481 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE 540

Query: 540 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDR 581
           VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDR
Sbjct: 541 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDR 582


>gi|35493801 ring finger protein 19 [Homo sapiens]
          Length = 838

 Score =  722 bits (1864), Expect = 0.0
 Identities = 349/480 (72%), Positives = 396/480 (82%), Gaps = 15/480 (3%)

Query: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIR 176
           +ECPLCL+R   +R P +++C HRSC DCLR YLR+EISESRV ISCPEC+ER NPHDIR
Sbjct: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIR 189

Query: 177 LLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTE 236
           L+L+D  LM KYEEFMLRR+L +DPDCRWCPAPDCGYAVIA+GCASCPKLTC REGC TE
Sbjct: 190 LILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTE 249

Query: 237 FCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGP--DDIKPCPRCSAYII 294
           FCYHCKQIWHPNQTCD ARQ+RAQ+LR+RT  +S +SY QESG   DDIKPCPRC+AYII
Sbjct: 250 FCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYII 309

Query: 295 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLI 354
           KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTL+
Sbjct: 310 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLV 369

Query: 355 GAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPV 414
           GAPVGI+LIAGIAIPAM+IGIPVYVGRKIH+RYEG+  SKHKRNLAI GGVTLSVI SPV
Sbjct: 370 GAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPV 429

Query: 415 IAAVSVGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDD-----GPITVA 469
           +AAV+VGIGVPIMLAYVYGVVPISLCR GGCGVS  NGKGV+IEFD+++     G  T  
Sbjct: 430 VAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAV 489

Query: 470 DAW---RALKNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGG 526
           D      A  NPSIGE S+ GLT  LS SGS  D +  ++   SETAS  AL+G +++G 
Sbjct: 490 DTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGS 549

Query: 527 ILSSGK-GKYSRLEVQADVQKEIF----PKDTASLGAISDNASTRAMAGSIISSYNPQDR 581
           +  S     ++RLEVQADVQKE +       T SLG +SDNAST+AMAGSI++SY P D+
Sbjct: 550 LSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDK 609


>gi|35493782 ring finger protein 19 [Homo sapiens]
          Length = 838

 Score =  722 bits (1864), Expect = 0.0
 Identities = 349/480 (72%), Positives = 396/480 (82%), Gaps = 15/480 (3%)

Query: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIR 176
           +ECPLCL+R   +R P +++C HRSC DCLR YLR+EISESRV ISCPEC+ER NPHDIR
Sbjct: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIR 189

Query: 177 LLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTE 236
           L+L+D  LM KYEEFMLRR+L +DPDCRWCPAPDCGYAVIA+GCASCPKLTC REGC TE
Sbjct: 190 LILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTE 249

Query: 237 FCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGP--DDIKPCPRCSAYII 294
           FCYHCKQIWHPNQTCD ARQ+RAQ+LR+RT  +S +SY QESG   DDIKPCPRC+AYII
Sbjct: 250 FCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYII 309

Query: 295 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLI 354
           KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTL+
Sbjct: 310 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLV 369

Query: 355 GAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPV 414
           GAPVGI+LIAGIAIPAM+IGIPVYVGRKIH+RYEG+  SKHKRNLAI GGVTLSVI SPV
Sbjct: 370 GAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPV 429

Query: 415 IAAVSVGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDD-----GPITVA 469
           +AAV+VGIGVPIMLAYVYGVVPISLCR GGCGVS  NGKGV+IEFD+++     G  T  
Sbjct: 430 VAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAV 489

Query: 470 DAW---RALKNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGG 526
           D      A  NPSIGE S+ GLT  LS SGS  D +  ++   SETAS  AL+G +++G 
Sbjct: 490 DTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGS 549

Query: 527 ILSSGK-GKYSRLEVQADVQKEIF----PKDTASLGAISDNASTRAMAGSIISSYNPQDR 581
           +  S     ++RLEVQADVQKE +       T SLG +SDNAST+AMAGSI++SY P D+
Sbjct: 550 LSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDK 609


>gi|38045938 ring finger protein 144 [Homo sapiens]
          Length = 292

 Score =  113 bits (283), Expect = 4e-25
 Identities = 74/269 (27%), Positives = 111/269 (41%), Gaps = 22/269 (8%)

Query: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPECS----ERLN 171
           V C LCL   P E+   +  C    C  CL+ Y+ L I E     ISCP+ +      L 
Sbjct: 18  VSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQ 77

Query: 172 PHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCERE 231
            ++I  ++A   +M +Y++    R +  DP   WCPA  C                 + +
Sbjct: 78  ENEIECMVA-AEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCK 136

Query: 232 GCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSA 291
            C+ EFC  CK  WHP Q C          +      TS  ++  E     IK CP+C  
Sbjct: 137 ACRMEFCSTCKASWHPGQGC-----PETMPITFLPGETSA-AFKMEEDDAPIKRCPKCKV 190

Query: 292 YIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD----LHYLSPSGCTFWGKKPWSRKKKIL 347
           YI +  D  C  M C  C   FCW C++ + D    +HY     C     K    +  ++
Sbjct: 191 YIER--DEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHY-DKGPCR---NKLGHSRASVI 244

Query: 348 WQLGTLIGAPVGISLIAGIAIPAMVIGIP 376
           W    ++G   G  L+  +A P +++  P
Sbjct: 245 WHRTQVVGIFAGFGLLLLVASPFLLLATP 273


>gi|50284696 IBR domain containing 2 [Homo sapiens]
          Length = 303

 Score =  103 bits (256), Expect = 6e-22
 Identities = 74/284 (26%), Positives = 115/284 (40%), Gaps = 24/284 (8%)

Query: 107 AEGGGPG----AEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPI 161
           AE   PG    A  + C LCL     ++   L  C    C  CL+ Y++L I E    PI
Sbjct: 14  AENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPI 73

Query: 162 SCPE--CSERLNPHDIRLLLADP-PLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAY 218
           +CP+  C       +  +    P      Y+     R +  DP   WCP  DC       
Sbjct: 74  TCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVA 133

Query: 219 GCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQES 278
                  +  E   C  +FC  CK  WH   +C     + +Q + + T+H +      E+
Sbjct: 134 SSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSC-----RDSQPIVLPTEHRALFGTDAEA 188

Query: 279 GPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD---LHYLSPSGCTFW 335
               IK CP C  Y I+ N+G C  M C  C   FCW C++ + +   L +     C   
Sbjct: 189 ---PIKQCPVCRVY-IERNEG-CAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCR-- 241

Query: 336 GKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYV 379
             K    +  ++W    ++G  VG+ +IA +  P +++  P  +
Sbjct: 242 -NKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCII 284


>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
           protein homolog 1 [Homo sapiens]
          Length = 557

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 62/212 (29%), Positives = 95/212 (44%), Gaps = 23/212 (10%)

Query: 114 AEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV--PISCPE--CSER 169
           A+++ C +C +  P      L  C H+ C  C   YL  +I E  +   ISCP   C   
Sbjct: 181 AQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDIL 239

Query: 170 LNPHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAV-IAYGCASCPKLTC 228
           ++ + +  L+ D  +  KY+  +   ++  +   +WCPAPDC + V + Y  A   +  C
Sbjct: 240 VDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKC 299

Query: 229 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPR 288
            R     +FC++C + WH    C        + L+   K     S        + K CP+
Sbjct: 300 GR-----QFCFNCGENWHDPVKC--------KWLKKWIKKCDDDSETSNWIAANTKECPK 346

Query: 289 CSAYIIKMNDGSCNHMTC--AVCGCEFCWLCM 318
           C   I K  DG CNHM C    C  EFCW+C+
Sbjct: 347 CHVTIEK--DGGCNHMVCRNQNCKAEFCWVCL 376


>gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo
           sapiens]
          Length = 1089

 Score = 93.2 bits (230), Expect = 6e-19
 Identities = 61/225 (27%), Positives = 99/225 (44%), Gaps = 29/225 (12%)

Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCP--ECSERLNPHDI 175
           C +C+  +     P  + C H  CR C   +L L+I E     I CP  +C + L P DI
Sbjct: 333 CDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQ-LVPVDI 391

Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAV--------------IAYGCA 221
              +    +  +Y +F ++ ++ ++P  +WCP P C  AV              +++   
Sbjct: 392 IESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLL 451

Query: 222 SCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPD 281
             P + C   G    FC+ C    H    C   +    +   ++ +   G+S   E   +
Sbjct: 452 RAPAVDC---GKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAAN 508

Query: 282 DI------KPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKE 320
            +      KPC  C + I K N+G CNHM CA C  +FCW+C++E
Sbjct: 509 CLWLLTNSKPCANCKSPIQK-NEG-CNHMQCAKCKYDFCWICLEE 551


>gi|5453557 ariadne homolog 2 [Homo sapiens]
          Length = 493

 Score = 89.7 bits (221), Expect = 7e-18
 Identities = 60/208 (28%), Positives = 91/208 (43%), Gaps = 30/208 (14%)

Query: 122 CLVRLPPERAPRLLS--CPHRSCRDCLRHYLRLEISES-RVPISC--PECSERLNPHDIR 176
           C V +   R   LLS  C H+ CR C   +  + + +   V +SC   +C  R     + 
Sbjct: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVF 198

Query: 177 LLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTE 236
            LL +  L  KY  ++ R Y+ S    + CP  DC   VI        ++ C R  C   
Sbjct: 199 PLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPM-VIRVQEPRARRVQCNR--CNEV 255

Query: 237 FCYHCKQIWHPNQTCDMARQ------QRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCS 290
           FC+ C+Q++H    C   R+        ++T    + HT              K CP+C+
Sbjct: 256 FCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHT--------------KDCPKCN 301

Query: 291 AYIIKMNDGSCNHMTCAVCGCEFCWLCM 318
             I K  +G CNHM C+ C  +FCW+C+
Sbjct: 302 ICIEK--NGGCNHMQCSKCKHDFCWMCL 327


>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
            sapiens]
          Length = 2517

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 63/217 (29%), Positives = 94/217 (43%), Gaps = 23/217 (10%)

Query: 119  CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCP--ECSERLNPHDI 175
            CP+C+  L  +     L C H  C+ C   YL   I ++ V   +CP  +C  +     I
Sbjct: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129

Query: 176  RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPD-CGYAVIAYG------CASCPKLTC 228
            R +++ P ++ KYE+ +LR Y+ S  +  WC  P  C   +   G      C+ C   +C
Sbjct: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASC 2189

Query: 229  EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPR 288
                C     ++     H +Q  D        ++  ++KH + L           K CP 
Sbjct: 2190 FN--CSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLIS---------KRCPS 2238

Query: 289  CSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH 325
            C A I K N+G C HMTCA C   FCW C+K     H
Sbjct: 2239 CQAPIEK-NEG-CLHMTCAKCNHGFCWRCLKSWKPNH 2273


>gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 59/226 (26%), Positives = 91/226 (40%), Gaps = 29/226 (12%)

Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175
           C +C            L C H  C+ CL+ Y  ++I + +V  ++CPE  C     P  +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279

Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235
           + L+ +  L  +Y+  +L+  L    D  +CP P C   V+      C    C    C  
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 334

Query: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------- 276
            FC  C+  +H    C +  ++    R + L+     K      YG+             
Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394

Query: 277 ESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 322
           E    + K CP C   I K++   CN MTC  C   FCW+CM  +S
Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438


>gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 59/226 (26%), Positives = 91/226 (40%), Gaps = 29/226 (12%)

Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175
           C +C            L C H  C+ CL+ Y  ++I + +V  ++CPE  C     P  +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279

Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235
           + L+ +  L  +Y+  +L+  L    D  +CP P C   V+      C    C    C  
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 334

Query: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------- 276
            FC  C+  +H    C +  ++    R + L+     K      YG+             
Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394

Query: 277 ESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 322
           E    + K CP C   I K++   CN MTC  C   FCW+CM  +S
Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438


>gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 59/226 (26%), Positives = 91/226 (40%), Gaps = 29/226 (12%)

Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175
           C +C            L C H  C+ CL+ Y  ++I + +V  ++CPE  C     P  +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279

Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235
           + L+ +  L  +Y+  +L+  L    D  +CP P C   V+      C    C    C  
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 334

Query: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------- 276
            FC  C+  +H    C +  ++    R + L+     K      YG+             
Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394

Query: 277 ESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 322
           E    + K CP C   I K++   CN MTC  C   FCW+CM  +S
Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438


>gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
          Length = 348

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 59/226 (26%), Positives = 91/226 (40%), Gaps = 29/226 (12%)

Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175
           C +C            L C H  C+ CL+ Y  ++I + +V  ++CPE  C     P  +
Sbjct: 94  CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153

Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235
           + L+ +  L  +Y+  +L+  L    D  +CP P C   V+      C    C    C  
Sbjct: 154 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 208

Query: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------- 276
            FC  C+  +H    C +  ++    R + L+     K      YG+             
Sbjct: 209 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 268

Query: 277 ESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 322
           E    + K CP C   I K++   CN MTC  C   FCW+CM  +S
Sbjct: 269 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 312


>gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 59/226 (26%), Positives = 91/226 (40%), Gaps = 29/226 (12%)

Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175
           C +C            L C H  C+ CL+ Y  ++I + +V  ++CPE  C     P  +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279

Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235
           + L+ +  L  +Y+  +L+  L    D  +CP P C   V+      C    C    C  
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 334

Query: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------- 276
            FC  C+  +H    C +  ++    R + L+     K      YG+             
Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394

Query: 277 ESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 322
           E    + K CP C   I K++   CN MTC  C   FCW+CM  +S
Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438


>gi|109150431 ring finger protein 31 [Homo sapiens]
          Length = 1072

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 69/284 (24%), Positives = 102/284 (35%), Gaps = 51/284 (17%)

Query: 118 ECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCPECSERLNPHDIR 176
           EC +C   LP  R   L SC    C DC R +  + + E  +  + CP C       D +
Sbjct: 698 ECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQ 757

Query: 177 LL------------LADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGC-ASC 223
           LL              +P     + + +    L  DP   WC     G+        A+C
Sbjct: 758 LLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQCSFGFIYEREQLEATC 817

Query: 224 PKLTCEREGCQTEFCYHCKQIW---HPNQTCDMARQQRAQTLRVRTKHTSGLS-YGQESG 279
           P+       C   FC  CK+ W   H  ++C+    Q  + +        GL+ Y QE+G
Sbjct: 818 PQ-------CHQTFCVRCKRQWEEQHRGRSCE--DFQNWKRMNDPEYQAQGLAMYLQENG 868

Query: 280 PDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEI--------------SDLH 325
            D    CP+C  +   +  G C H  C  C  +FC  C                    LH
Sbjct: 869 ID----CPKCK-FSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLH 923

Query: 326 YLSPSGCTFWGKKPWS--RKKKILWQLGTLIGA--PVGISLIAG 365
              P  C F+  + W+  R +K+L     +     P G   + G
Sbjct: 924 GHHPRDCLFY-LRDWTALRLQKLLQDNNVMFNTEPPAGARAVPG 966


>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1
           isoform 1 [Homo sapiens]
          Length = 468

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 84/332 (25%), Positives = 111/332 (33%), Gaps = 95/332 (28%)

Query: 55  EPPPPAAQPPPAPA---PAAAQGPPPEAL----------PAEPAAE----AEAEAAAAAA 97
           EP PP    P  P    P A   PPP             P  P  E    A  EA    A
Sbjct: 127 EPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPA 186

Query: 98  EPGFDDEEAAEGGGP--------------------------------GAEEVECPLCLVR 125
               D+EE A   G                                   E  ECP+C   
Sbjct: 187 SYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSV 246

Query: 126 LPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCP------ECSERLNPHDIRLLL 179
           L P  A  L  C H  CR+CL+  +R   +     +SCP       CS +L   +I+ LL
Sbjct: 247 LAPGEAVVLRECLHTFCRECLQGTIR---NSQEAEVSCPFIDNTYSCSGKLLEREIKALL 303

Query: 180 ADPPLMHKYEEFM-----------LRRYLASDPDCR-WCPAPDCGYAVIAYGCASCPKLT 227
                   Y+ F+              Y    PDC+ WC   D    V  + C  C  + 
Sbjct: 304 TP----EDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED---DVNEFTCPVCFHVN 356

Query: 228 CEREGCQTEFCYHCKQIWHPNQTCDMARQQ---RAQTLRVRTKHTSGLSYGQESGPDDIK 284
                     C  CK I H    C   ++    RAQ      + T  L    + G  +  
Sbjct: 357 ----------CLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQG--EAM 403

Query: 285 PCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWL 316
            CP+C   +++  DG C+ + C VC  E CW+
Sbjct: 404 RCPQCQ-IVVQKKDG-CDWIRCTVCHTEICWV 433


>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
           isoform 2 [Homo sapiens]
          Length = 510

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 84/332 (25%), Positives = 111/332 (33%), Gaps = 95/332 (28%)

Query: 55  EPPPPAAQPPPAPA---PAAAQGPPPEAL----------PAEPAAE----AEAEAAAAAA 97
           EP PP    P  P    P A   PPP             P  P  E    A  EA    A
Sbjct: 169 EPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPA 228

Query: 98  EPGFDDEEAAEGGGP--------------------------------GAEEVECPLCLVR 125
               D+EE A   G                                   E  ECP+C   
Sbjct: 229 SYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSV 288

Query: 126 LPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCP------ECSERLNPHDIRLLL 179
           L P  A  L  C H  CR+CL+  +R   +     +SCP       CS +L   +I+ LL
Sbjct: 289 LAPGEAVVLRECLHTFCRECLQGTIR---NSQEAEVSCPFIDNTYSCSGKLLEREIKALL 345

Query: 180 ADPPLMHKYEEFM-----------LRRYLASDPDCR-WCPAPDCGYAVIAYGCASCPKLT 227
                   Y+ F+              Y    PDC+ WC   D    V  + C  C  + 
Sbjct: 346 TP----EDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED---DVNEFTCPVCFHVN 398

Query: 228 CEREGCQTEFCYHCKQIWHPNQTCDMARQQ---RAQTLRVRTKHTSGLSYGQESGPDDIK 284
                     C  CK I H    C   ++    RAQ      + T  L    + G  +  
Sbjct: 399 ----------CLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQG--EAM 445

Query: 285 PCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWL 316
            CP+C   +++  DG C+ + C VC  E CW+
Sbjct: 446 RCPQCQ-IVVQKKDG-CDWIRCTVCHTEICWV 475


>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
          Length = 866

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 55/236 (23%), Positives = 96/236 (40%), Gaps = 32/236 (13%)

Query: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPE--CSERLNPH 173
           +EC  C    P E   +     H  C++CL  Y +  +  S ++ +SC E  C+      
Sbjct: 513 IECRCCYGEFPFEELTQCADA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTS 571

Query: 174 DIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGC 233
           ++  +L    +++KY E      +A+         P C +  +    +   + +C    C
Sbjct: 572 ELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD--SDVKRFSCPNPHC 628

Query: 234 QTEFCYHCKQIW--HPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSA 291
           + E C  C+ +W  H   TC+   ++    ++ RT      S  ++     I+ C +C  
Sbjct: 629 RKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRT------SIEEKMTAARIRKCHKCGT 680

Query: 292 YIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGCTFW 335
            +IK     CN M+C  CG + C+LC   I+       H  SP       S C+ W
Sbjct: 681 GLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLW 733


>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
          Length = 923

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 55/236 (23%), Positives = 96/236 (40%), Gaps = 32/236 (13%)

Query: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPE--CSERLNPH 173
           +EC  C    P E   +     H  C++CL  Y +  +  S ++ +SC E  C+      
Sbjct: 570 IECRCCYGEFPFEELTQCADA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTS 628

Query: 174 DIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGC 233
           ++  +L    +++KY E      +A+         P C +  +    +   + +C    C
Sbjct: 629 ELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD--SDVKRFSCPNPHC 685

Query: 234 QTEFCYHCKQIW--HPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSA 291
           + E C  C+ +W  H   TC+   ++    ++ RT      S  ++     I+ C +C  
Sbjct: 686 RKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRT------SIEEKMTAARIRKCHKCGT 737

Query: 292 YIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGCTFW 335
            +IK     CN M+C  CG + C+LC   I+       H  SP       S C+ W
Sbjct: 738 GLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLW 790


>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
          Length = 835

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 43/126 (34%), Positives = 54/126 (42%), Gaps = 21/126 (16%)

Query: 60  AAQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEV-- 117
           AA   P P   +A G   E     P+A A A A+AAA+ P         GGG  A E+  
Sbjct: 15  AASGSPGPGEGSAGG---EKRSTAPSAAASASASAAASSPA--------GGGAEALELLE 63

Query: 118 ECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES--------RVPISCPECSER 169
            C +C  RL PER PRLL C H +C  CL        + S           + CP C ++
Sbjct: 64  HCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQ 123

Query: 170 LNPHDI 175
               DI
Sbjct: 124 CFSKDI 129



 Score = 29.6 bits (65), Expect = 8.1
 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 7/74 (9%)

Query: 58  PPAAQPPPAPAP---AAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGA 114
           PP A   P   P   A A+GP  E     P   + + + ++  E    +  +A GGGPG 
Sbjct: 565 PPTATEGPETKPVLMALAEGPGAEG----PRLASPSGSTSSGLEVVAPEGTSAPGGGPGT 620

Query: 115 EEVECPLCLVRLPP 128
            +    +C V   P
Sbjct: 621 LDDSATICRVCQKP 634


>gi|169790973 parkin isoform 3 [Homo sapiens]
          Length = 316

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 14/122 (11%)

Query: 206 CPAPDCGYAVIAYGCASCPKLTCERE---GCQTEFCYHCKQIWHPNQTCDM--ARQQRAQ 260
           CP P CG  ++        K+TCE     GC   FC  CK+ +H  +   +  A     Q
Sbjct: 183 CPRPGCGAGLLPE--PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQ 240

Query: 261 TLRVRTKHTSGLSY---GQESGPDDIKPCPRCSAYIIKMNDGSCNHMTC--AVCGCEFCW 315
             RV  +      +    +E+     KPCPRC   + K  +G C HM C    C  E+CW
Sbjct: 241 AYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEK--NGGCMHMKCPQPQCRLEWCW 298

Query: 316 LC 317
            C
Sbjct: 299 NC 300


>gi|169790971 parkin isoform 2 [Homo sapiens]
          Length = 437

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 14/122 (11%)

Query: 206 CPAPDCGYAVIAYGCASCPKLTCERE---GCQTEFCYHCKQIWHPNQTCDM--ARQQRAQ 260
           CP P CG  ++        K+TCE     GC   FC  CK+ +H  +   +  A     Q
Sbjct: 304 CPRPGCGAGLLPE--PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQ 361

Query: 261 TLRVRTKHTSGLSY---GQESGPDDIKPCPRCSAYIIKMNDGSCNHMTC--AVCGCEFCW 315
             RV  +      +    +E+     KPCPRC   + K  +G C HM C    C  E+CW
Sbjct: 362 AYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEK--NGGCMHMKCPQPQCRLEWCW 419

Query: 316 LC 317
            C
Sbjct: 420 NC 421


>gi|169790969 parkin isoform 1 [Homo sapiens]
          Length = 465

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 14/122 (11%)

Query: 206 CPAPDCGYAVIAYGCASCPKLTCERE---GCQTEFCYHCKQIWHPNQTCDM--ARQQRAQ 260
           CP P CG  ++        K+TCE     GC   FC  CK+ +H  +   +  A     Q
Sbjct: 332 CPRPGCGAGLLPE--PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQ 389

Query: 261 TLRVRTKHTSGLSY---GQESGPDDIKPCPRCSAYIIKMNDGSCNHMTC--AVCGCEFCW 315
             RV  +      +    +E+     KPCPRC   + K  +G C HM C    C  E+CW
Sbjct: 390 AYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEK--NGGCMHMKCPQPQCRLEWCW 447

Query: 316 LC 317
            C
Sbjct: 448 NC 449


>gi|22749145 ring finger protein 217 [Homo sapiens]
          Length = 275

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 49/197 (24%), Positives = 80/197 (40%), Gaps = 27/197 (13%)

Query: 152 LEISESRVPISCP--ECSERLNPHDIRLLLADPPLMHKYEEFM-LRRYLASDPDCRWCPA 208
           +++   +V I CP  EC E L    +   L     + KY+ F+ L R  +S   C  C  
Sbjct: 1   MKVQLGQVEIKCPITECFEFLEETTVVYNLTHEDSI-KYKYFLELGRIDSSTKPCPQCKH 59

Query: 209 ----PDCGYAVIAYGCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRV 264
                  G+        S  K+ C    CQ  +C+ C   WH    C    ++  +  ++
Sbjct: 60  FTTFKKKGHIPTPSRSESKYKIQCPT--CQFVWCFKCHSPWHEGVNC----KEYKKGDKL 113

Query: 265 RTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL 324
                S + +GQ +     + CP+C  +I +     C+HMTC+ C   FC+ C +    L
Sbjct: 114 LRHWASEIEHGQRNA----QKCPKCKIHIQRTE--GCDHMTCSQCNTNFCYRCGERYRQL 167

Query: 325 HY-------LSPSGCTF 334
            +       LS  GC +
Sbjct: 168 RFFGDHTSNLSIFGCKY 184


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 41/102 (40%), Positives = 47/102 (46%), Gaps = 5/102 (4%)

Query: 33  LTLHSVFSASARGRRARAKPQ-AEPPPPAAQPPPA-PAPAAAQGPPPEALPAEPAAEAEA 90
           + L +   ASA    A  +P  AE  P   QPPPA  APA  Q PP E  PAE      A
Sbjct: 593 IQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE-VQPPPA 651

Query: 91  EAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAP 132
           E A A  +P   +E  AE   P AE  E P  +  LP E  P
Sbjct: 652 EEAPAEVQPPPAEEAPAEVQPPPAE--EAPAEVQSLPAEETP 691



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 32/73 (43%), Positives = 32/73 (43%), Gaps = 12/73 (16%)

Query: 48  ARAKPQAEPPPPAA------QPPPA-PAPAAAQGPPPEALPAE----PAAEAEAEAAAAA 96
           A   P    PPPA       QPPPA  APA  Q PP E  PAE    PA E   E   AA
Sbjct: 639 AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAA 698

Query: 97  A-EPGFDDEEAAE 108
              P  DD  A E
Sbjct: 699 VHSPPADDVPAEE 711



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 3/57 (5%)

Query: 60  AAQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEE 116
           A + P   AP   Q P P+   AE A+ AE +  AA   P   DE  AE   P +EE
Sbjct: 445 AMETPAEEAPTEFQSPLPKETTAEEAS-AEIQLLAATEPPA--DETPAEARSPLSEE 498



 Score = 29.6 bits (65), Expect = 8.1
 Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 60  AAQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAE 108
           A +PP    PA A+ P  E   AE   EA AE  +  AE    +E +AE
Sbjct: 479 ATEPPADETPAEARSPLSEETSAE---EAHAEVQSPLAEETTAEEASAE 524


>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
          Length = 1006

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 52/185 (28%), Positives = 69/185 (37%), Gaps = 27/185 (14%)

Query: 2   GSEKDSESPRSTSLHAAAPDPK---CRSGG----RRRRLTLHSVFSASARGRRARAKPQA 54
           GSE  S+SP S S+  A  DP    C +      R    T+H  +  ++R      +P A
Sbjct: 662 GSE-GSQSPGS-SVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAA 719

Query: 55  EPPPPAAQPPPAPAPA---------------AAQGPPPEALPAEPAAEAEAEAAAAAAEP 99
            P PP    PPAP+PA               AA  PPP      PA E+    + + + P
Sbjct: 720 PPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGP 779

Query: 100 GFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV 159
           G      A   GP A+         R P   AP      +  C  C   +  LE   +  
Sbjct: 780 GL---APARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHK 836

Query: 160 PISCP 164
             SCP
Sbjct: 837 KYSCP 841



 Score = 36.2 bits (82), Expect = 0.086
 Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 2/40 (5%)

Query: 43  ARGRRARAKPQAEPPPPAAQPPPAPAPAAAQGPPPEALPA 82
           +RG R    P+ + PPP   P PA AP A   PPP A P+
Sbjct: 914 SRGPRDGLGPEPQEPPPGPPPSPAAAPEAV--PPPPAPPS 951



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 12/73 (16%)

Query: 53  QAEPPPPAAQPPPAPAPAAAQGPP-----PEALPAEPAAEAEAEAAAAAAEPGFDDEEAA 107
           +A    PAA+ P AP P  A+ PP     P+A  + P   A  E A  AA P    E+ A
Sbjct: 604 RAPEDAPAARRPKAP-PGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATP----EDGA 658

Query: 108 EGGGPGAEEVECP 120
             GG G+E  + P
Sbjct: 659 --GGRGSEGSQSP 669



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 29/98 (29%), Positives = 36/98 (36%), Gaps = 23/98 (23%)

Query: 50  AKPQAEPPPPAAQ-PPPAPAPAAAQGP---------------PPEALPAEPAAEAEAEAA 93
           A P  E   PA + P PAPAPAA+  P               PP   P  PAA  EA   
Sbjct: 886 AGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEA-VP 944

Query: 94  AAAAEPGFDDE------EAAEGGGPGAEEVECPLCLVR 125
              A P + D+      +      P      C LC ++
Sbjct: 945 PPPAPPSYSDKGVQTPSKGTPAPLPNGNHRYCRLCNIK 982


>gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo
           sapiens]
          Length = 282

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 48/188 (25%), Positives = 68/188 (36%), Gaps = 41/188 (21%)

Query: 56  PPPPAAQPPPAPAPAAAQGPPPEALPAEPAAEAE-AEAAAAAAEPGFDDEEAAEGGGPGA 114
           P P A   PPAP    +  P P++  A P  E +   +     E    D ++AE G P  
Sbjct: 11  PLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQGDPAG 70

Query: 115 E--EVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNP 172
           E  EV C  CL      +A        +SC  C+ +Y                C E L P
Sbjct: 71  EGKEVLCDFCLDDTRRVKAV-------KSCLTCMVNY----------------CEEHLQP 107

Query: 173 HDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREG 232
           H + + L    L               D + R+CPA    ++ ++  C  CP   C  + 
Sbjct: 108 HQVNIKLQSHLLTEP----------VKDHNWRYCPA---HHSPLSAFC--CPDQQCICQD 152

Query: 233 CQTEFCYH 240
           C  E   H
Sbjct: 153 CCQEHSGH 160


>gi|48255913 tripartite motif-containing 16 [Homo sapiens]
          Length = 564

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 48/188 (25%), Positives = 68/188 (36%), Gaps = 41/188 (21%)

Query: 56  PPPPAAQPPPAPAPAAAQGPPPEALPAEPAAEAE-AEAAAAAAEPGFDDEEAAEGGGPGA 114
           P P A   PPAP    +  P P++  A P  E +   +     E    D ++AE G P  
Sbjct: 11  PLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQGDPAG 70

Query: 115 E--EVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNP 172
           E  EV C  CL      +A        +SC  C+ +Y                C E L P
Sbjct: 71  EGKEVLCDFCLDDTRRVKAV-------KSCLTCMVNY----------------CEEHLQP 107

Query: 173 HDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREG 232
           H + + L    L               D + R+CPA    ++ ++  C  CP   C  + 
Sbjct: 108 HQVNIKLQSHLLTEP----------VKDHNWRYCPA---HHSPLSAFC--CPDQQCICQD 152

Query: 233 CQTEFCYH 240
           C  E   H
Sbjct: 153 CCQEHSGH 160


>gi|239753500 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 213

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 37/103 (35%), Positives = 44/103 (42%), Gaps = 17/103 (16%)

Query: 44  RGRRARAKPQAEPPPPAAQPPPAPAPAAAQGPPPEALPAEPAAEAEAE----AAAAAAEP 99
           RG RA     +    PA   PPAP P   + P P A   EPAA   A     AAA+A   
Sbjct: 2   RGLRASGASPSPRSSPARSHPPAPLPFPERLPRPAA--KEPAARTPARQVFPAAASAGRE 59

Query: 100 GFDDEEAAEGGGPG---AEEVECPLCLVRLPPERAPRLLSCPH 139
           G    + A G  PG   + E+         PP RAPR +  PH
Sbjct: 60  GSAAPDGARGSTPGLAASRELS--------PPPRAPRTVPAPH 94



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 33/119 (27%), Positives = 40/119 (33%), Gaps = 24/119 (20%)

Query: 18  AAPDPKCRSGGRRRRLTLHSVFSASAR-GRRARAKP--------------QAEPPPPAAQ 62
           AA +P  R+  R+       VF A+A  GR   A P              +  PPP A +
Sbjct: 36  AAKEPAARTPARQ-------VFPAAASAGREGSAAPDGARGSTPGLAASRELSPPPRAPR 88

Query: 63  PPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPL 121
             PAP P  +    P A P                EPG   E  A    P      CPL
Sbjct: 89  TVPAPHPRLSPARRPGAEPENKFVALRGSHKTRNREPGMLRE--AFKSAPPTGSGYCPL 145


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,788,348
Number of Sequences: 37866
Number of extensions: 1590170
Number of successful extensions: 37886
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 754
Number of HSP's successfully gapped in prelim test: 1158
Number of HSP's that attempted gapping in prelim test: 18010
Number of HSP's gapped (non-prelim): 13081
length of query: 587
length of database: 18,247,518
effective HSP length: 108
effective length of query: 479
effective length of database: 14,157,990
effective search space: 6781677210
effective search space used: 6781677210
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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