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Search of human proteins with 188219577
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
(732 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 1511 0.0
gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 1198 0.0
gi|35493801 ring finger protein 19 [Homo sapiens] 759 0.0
gi|35493782 ring finger protein 19 [Homo sapiens] 759 0.0
gi|38045938 ring finger protein 144 [Homo sapiens] 111 3e-24
gi|50284696 IBR domain containing 2 [Homo sapiens] 102 1e-21
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 98 3e-20
gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa... 92 1e-18
gi|5453557 ariadne homolog 2 [Homo sapiens] 89 1e-17
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 89 2e-17
gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 78 3e-14
gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 78 3e-14
gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 78 3e-14
gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 78 3e-14
gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 78 3e-14
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 69 1e-11
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 69 1e-11
gi|109150431 ring finger protein 31 [Homo sapiens] 68 3e-11
gi|46370057 ring finger protein 216 isoform b [Homo sapiens] 64 7e-10
gi|46358403 ring finger protein 216 isoform a [Homo sapiens] 64 7e-10
gi|169790973 parkin isoform 3 [Homo sapiens] 58 3e-08
gi|169790971 parkin isoform 2 [Homo sapiens] 58 3e-08
gi|169790969 parkin isoform 1 [Homo sapiens] 58 3e-08
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens] 58 4e-08
gi|22749145 ring finger protein 217 [Homo sapiens] 55 3e-07
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 50 6e-06
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] 50 7e-06
gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo ... 49 1e-05
gi|48255913 tripartite motif-containing 16 [Homo sapiens] 49 1e-05
gi|239753500 PREDICTED: hypothetical protein [Homo sapiens] 47 5e-05
>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
Length = 732
Score = 1511 bits (3911), Expect = 0.0
Identities = 732/732 (100%), Positives = 732/732 (100%)
Query: 1 MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA 60
MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA
Sbjct: 1 MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA 60
Query: 61 AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP 120
AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP
Sbjct: 61 AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP 120
Query: 121 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA 180
LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA
Sbjct: 121 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA 180
Query: 181 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH 240
DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH
Sbjct: 181 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH 240
Query: 241 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDG 300
CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDG
Sbjct: 241 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDG 300
Query: 301 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG 360
SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG
Sbjct: 301 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG 360
Query: 361 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS 420
ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS
Sbjct: 361 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS 420
Query: 421 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS 480
VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS
Sbjct: 421 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS 480
Query: 481 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE 540
IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE
Sbjct: 481 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE 540
Query: 541 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHY 600
VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHY
Sbjct: 541 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHY 600
Query: 601 QLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEEDPPCRHQSCEQKDCLASKPWDISLAQP 660
QLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEEDPPCRHQSCEQKDCLASKPWDISLAQP
Sbjct: 601 QLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEEDPPCRHQSCEQKDCLASKPWDISLAQP 660
Query: 661 ESIRSDLESSDAQSDDVPDITSDECGSPRSHTAACPSTPRAQGAPSPSAHMNLSALAEGQ 720
ESIRSDLESSDAQSDDVPDITSDECGSPRSHTAACPSTPRAQGAPSPSAHMNLSALAEGQ
Sbjct: 661 ESIRSDLESSDAQSDDVPDITSDECGSPRSHTAACPSTPRAQGAPSPSAHMNLSALAEGQ 720
Query: 721 TVLKPEGGEARV 732
TVLKPEGGEARV
Sbjct: 721 TVLKPEGGEARV 732
>gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
Length = 587
Score = 1198 bits (3100), Expect = 0.0
Identities = 581/582 (99%), Positives = 581/582 (99%), Gaps = 1/582 (0%)
Query: 1 MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA 60
MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA
Sbjct: 1 MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA 60
Query: 61 AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP 120
AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP
Sbjct: 61 AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP 120
Query: 121 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA 180
LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA
Sbjct: 121 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA 180
Query: 181 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH 240
DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH
Sbjct: 181 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH 240
Query: 241 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDG 300
CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGP DDIKPCPRCSAYIIKMNDG
Sbjct: 241 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGP-DDIKPCPRCSAYIIKMNDG 299
Query: 301 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG 360
SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG
Sbjct: 300 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG 359
Query: 361 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS 420
ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS
Sbjct: 360 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS 419
Query: 421 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS 480
VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS
Sbjct: 420 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS 479
Query: 481 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE 540
IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE
Sbjct: 480 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE 539
Query: 541 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDR 582
VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDR
Sbjct: 540 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDR 581
>gi|35493801 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 759 bits (1961), Expect = 0.0
Identities = 390/610 (63%), Positives = 451/610 (73%), Gaps = 24/610 (3%)
Query: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIR 176
+ECPLCL+R +R P +++C HRSC DCLR YLR+EISESRV ISCPEC+ER NPHDIR
Sbjct: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIR 189
Query: 177 LLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTE 236
L+L+D LM KYEEFMLRR+L +DPDCRWCPAPDCGYAVIA+GCASCPKLTC REGC TE
Sbjct: 190 LILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTE 249
Query: 237 FCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPA-DDIKPCPRCSAYII 295
FCYHCKQIWHPNQTCD ARQ+RAQ+LR+RT +S +SY QESG A DDIKPCPRC+AYII
Sbjct: 250 FCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYII 309
Query: 296 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLI 355
KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTL+
Sbjct: 310 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLV 369
Query: 356 GAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPV 415
GAPVGI+LIAGIAIPAM+IGIPVYVGRKIH+RYEG+ SKHKRNLAI GGVTLSVI SPV
Sbjct: 370 GAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPV 429
Query: 416 IAAVSVGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDD-----GPITVA 470
+AAV+VGIGVPIMLAYVYGVVPISLCR GGCGVS NGKGV+IEFD+++ G T
Sbjct: 430 VAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAV 489
Query: 471 DAW---RALKNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGG 527
D A NPSIGE S+ GLT LS SGS D + ++ SETAS AL+G +++G
Sbjct: 490 DTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGS 549
Query: 528 ILSSGK-GKYSRLEVQADVQKEIF----PKDTASLGAISDNASTRAMAGSIISSYNPQDR 582
+ S ++RLEVQADVQKE + T SLG +SDNAST+AMAGSI++SY P D+
Sbjct: 550 LSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDK 609
Query: 583 ECNNMEIQVDIEAKPSHYQLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEEDPPCRHQSC 642
E N+ME+QVDIE+KPS ++ SGSS+ D + GS G E S
Sbjct: 610 EGNSMEVQVDIESKPSKFRHNSGSSSVDD----GSATRSHAGGSSSGLPEGKSSATKWSK 665
Query: 643 EQKDCLASKPWDISLAQPESIRSDLESSDAQSDDVPDITSDECGSPRSHTAACPSTPRAQ 702
E SK + I E DAQ + S E +P S + + PS
Sbjct: 666 EATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAP-SLSDSMPSV---- 720
Query: 703 GAPSPSAHMN 712
A S S+H +
Sbjct: 721 -ADSHSSHFS 729
>gi|35493782 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 759 bits (1961), Expect = 0.0
Identities = 390/610 (63%), Positives = 451/610 (73%), Gaps = 24/610 (3%)
Query: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIR 176
+ECPLCL+R +R P +++C HRSC DCLR YLR+EISESRV ISCPEC+ER NPHDIR
Sbjct: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIR 189
Query: 177 LLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTE 236
L+L+D LM KYEEFMLRR+L +DPDCRWCPAPDCGYAVIA+GCASCPKLTC REGC TE
Sbjct: 190 LILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTE 249
Query: 237 FCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPA-DDIKPCPRCSAYII 295
FCYHCKQIWHPNQTCD ARQ+RAQ+LR+RT +S +SY QESG A DDIKPCPRC+AYII
Sbjct: 250 FCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYII 309
Query: 296 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLI 355
KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTL+
Sbjct: 310 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLV 369
Query: 356 GAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPV 415
GAPVGI+LIAGIAIPAM+IGIPVYVGRKIH+RYEG+ SKHKRNLAI GGVTLSVI SPV
Sbjct: 370 GAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPV 429
Query: 416 IAAVSVGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDD-----GPITVA 470
+AAV+VGIGVPIMLAYVYGVVPISLCR GGCGVS NGKGV+IEFD+++ G T
Sbjct: 430 VAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAV 489
Query: 471 DAW---RALKNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGG 527
D A NPSIGE S+ GLT LS SGS D + ++ SETAS AL+G +++G
Sbjct: 490 DTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGS 549
Query: 528 ILSSGK-GKYSRLEVQADVQKEIF----PKDTASLGAISDNASTRAMAGSIISSYNPQDR 582
+ S ++RLEVQADVQKE + T SLG +SDNAST+AMAGSI++SY P D+
Sbjct: 550 LSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDK 609
Query: 583 ECNNMEIQVDIEAKPSHYQLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEEDPPCRHQSC 642
E N+ME+QVDIE+KPS ++ SGSS+ D + GS G E S
Sbjct: 610 EGNSMEVQVDIESKPSKFRHNSGSSSVDD----GSATRSHAGGSSSGLPEGKSSATKWSK 665
Query: 643 EQKDCLASKPWDISLAQPESIRSDLESSDAQSDDVPDITSDECGSPRSHTAACPSTPRAQ 702
E SK + I E DAQ + S E +P S + + PS
Sbjct: 666 EATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAP-SLSDSMPSV---- 720
Query: 703 GAPSPSAHMN 712
A S S+H +
Sbjct: 721 -ADSHSSHFS 729
>gi|38045938 ring finger protein 144 [Homo sapiens]
Length = 292
Score = 111 bits (277), Expect = 3e-24
Identities = 75/270 (27%), Positives = 112/270 (41%), Gaps = 23/270 (8%)
Query: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPECS----ERLN 171
V C LCL P E+ + C C CL+ Y+ L I E ISCP+ + L
Sbjct: 18 VSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQ 77
Query: 172 PHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCERE 231
++I ++A +M +Y++ R + DP WCPA C + +
Sbjct: 78 ENEIECMVA-AEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCK 136
Query: 232 GCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCS 291
C+ EFC CK WHP Q C + TS ++ E A IK CP+C
Sbjct: 137 ACRMEFCSTCKASWHPGQGC-----PETMPITFLPGETSA-AFKMEEDDA-PIKRCPKCK 189
Query: 292 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD----LHYLSPSGCTFWGKKPWSRKKKI 347
YI + D C M C C FCW C++ + D +HY C K + +
Sbjct: 190 VYIER--DEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHY-DKGPCR---NKLGHSRASV 243
Query: 348 LWQLGTLIGAPVGISLIAGIAIPAMVIGIP 377
+W ++G G L+ +A P +++ P
Sbjct: 244 IWHRTQVVGIFAGFGLLLLVASPFLLLATP 273
>gi|50284696 IBR domain containing 2 [Homo sapiens]
Length = 303
Score = 102 bits (255), Expect = 1e-21
Identities = 74/285 (25%), Positives = 115/285 (40%), Gaps = 25/285 (8%)
Query: 107 AEGGGPG----AEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPI 161
AE PG A + C LCL ++ L C C CL+ Y++L I E PI
Sbjct: 14 AENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPI 73
Query: 162 SCPE--CSERLNPHDIRLLLADP-PLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAY 218
+CP+ C + + P Y+ R + DP WCP DC
Sbjct: 74 TCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVA 133
Query: 219 GCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQES 278
+ E C +FC CK WH +C + +Q + + T+H + E+
Sbjct: 134 SSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSC-----RDSQPIVLPTEHRALFGTDAEA 188
Query: 279 GPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD---LHYLSPSGCTF 335
IK CP C Y I+ N+G C M C C FCW C++ + + L + C
Sbjct: 189 ----PIKQCPVCRVY-IERNEG-CAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCR- 241
Query: 336 WGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYV 380
K + ++W ++G VG+ +IA + P +++ P +
Sbjct: 242 --NKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCII 284
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
Length = 557
Score = 97.8 bits (242), Expect = 3e-20
Identities = 63/213 (29%), Positives = 97/213 (45%), Gaps = 24/213 (11%)
Query: 114 AEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV--PISCPE--CSER 169
A+++ C +C + P L C H+ C C YL +I E + ISCP C
Sbjct: 181 AQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDIL 239
Query: 170 LNPHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAV-IAYGCASCPKLTC 228
++ + + L+ D + KY+ + ++ + +WCPAPDC + V + Y A + C
Sbjct: 240 VDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKC 299
Query: 229 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCP 288
R +FC++C + WH C + L+ K S + A + K CP
Sbjct: 300 GR-----QFCFNCGENWHDPVKC--------KWLKKWIKKCDDDS-ETSNWIAANTKECP 345
Query: 289 RCSAYIIKMNDGSCNHMTC--AVCGCEFCWLCM 319
+C I K DG CNHM C C EFCW+C+
Sbjct: 346 KCHVTIEK--DGGCNHMVCRNQNCKAEFCWVCL 376
>gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo
sapiens]
Length = 1089
Score = 92.4 bits (228), Expect = 1e-18
Identities = 61/225 (27%), Positives = 98/225 (43%), Gaps = 28/225 (12%)
Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCP--ECSERLNPHDI 175
C +C+ + P + C H CR C +L L+I E I CP +C + L P DI
Sbjct: 333 CDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQ-LVPVDI 391
Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAV--------------IAYGCA 221
+ + +Y +F ++ ++ ++P +WCP P C AV +++
Sbjct: 392 IESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLL 451
Query: 222 SCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGP- 280
P + C G FC+ C H C + + ++ + G+S E
Sbjct: 452 RAPAVDC---GKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAAN 508
Query: 281 ----ADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKE 321
+ KPC C + I K N+G CNHM CA C +FCW+C++E
Sbjct: 509 CLWLLTNSKPCANCKSPIQK-NEG-CNHMQCAKCKYDFCWICLEE 551
>gi|5453557 ariadne homolog 2 [Homo sapiens]
Length = 493
Score = 89.4 bits (220), Expect = 1e-17
Identities = 60/209 (28%), Positives = 91/209 (43%), Gaps = 31/209 (14%)
Query: 122 CLVRLPPERAPRLLS--CPHRSCRDCLRHYLRLEISES-RVPISC--PECSERLNPHDIR 176
C V + R LLS C H+ CR C + + + + V +SC +C R +
Sbjct: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVF 198
Query: 177 LLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTE 236
LL + L KY ++ R Y+ S + CP DC VI ++ C R C
Sbjct: 199 PLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPM-VIRVQEPRARRVQCNR--CNEV 255
Query: 237 FCYHCKQIWHPNQTCDMARQ------QRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRC 290
FC+ C+Q++H C R+ ++T + HT K CP+C
Sbjct: 256 FCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHT---------------KDCPKC 300
Query: 291 SAYIIKMNDGSCNHMTCAVCGCEFCWLCM 319
+ I K +G CNHM C+ C +FCW+C+
Sbjct: 301 NICIEK--NGGCNHMQCSKCKHDFCWMCL 327
>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
sapiens]
Length = 2517
Score = 88.6 bits (218), Expect = 2e-17
Identities = 63/218 (28%), Positives = 94/218 (43%), Gaps = 24/218 (11%)
Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCP--ECSERLNPHDI 175
CP+C+ L + L C H C+ C YL I ++ V +CP +C + I
Sbjct: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129
Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPD-CGYAVIAYG------CASCPKLTC 228
R +++ P ++ KYE+ +LR Y+ S + WC P C + G C+ C +C
Sbjct: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASC 2189
Query: 229 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCP 288
C ++ H +Q D ++ ++KH + L K CP
Sbjct: 2190 FN--CSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLIS----------KRCP 2237
Query: 289 RCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH 326
C A I K N+G C HMTCA C FCW C+K H
Sbjct: 2238 SCQAPIEK-NEG-CLHMTCAKCNHGFCWRCLKSWKPNH 2273
>gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 77.8 bits (190), Expect = 3e-14
Identities = 58/226 (25%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175
C +C L C H C+ CL+ Y ++I + +V ++CPE C P +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235
+ L+ + L +Y+ +L+ L D +CP P C V+ C C C
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGIC--SSCNF 334
Query: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------E 277
FC C+ +H C + ++ R + L+ K YG+ +
Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394
Query: 278 SGPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 323
+ K CP C I K++ CN MTC C FCW+CM +S
Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438
>gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 77.8 bits (190), Expect = 3e-14
Identities = 58/226 (25%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175
C +C L C H C+ CL+ Y ++I + +V ++CPE C P +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235
+ L+ + L +Y+ +L+ L D +CP P C V+ C C C
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGIC--SSCNF 334
Query: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------E 277
FC C+ +H C + ++ R + L+ K YG+ +
Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394
Query: 278 SGPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 323
+ K CP C I K++ CN MTC C FCW+CM +S
Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438
>gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 77.8 bits (190), Expect = 3e-14
Identities = 58/226 (25%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175
C +C L C H C+ CL+ Y ++I + +V ++CPE C P +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235
+ L+ + L +Y+ +L+ L D +CP P C V+ C C C
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGIC--SSCNF 334
Query: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------E 277
FC C+ +H C + ++ R + L+ K YG+ +
Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394
Query: 278 SGPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 323
+ K CP C I K++ CN MTC C FCW+CM +S
Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438
>gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
Length = 348
Score = 77.8 bits (190), Expect = 3e-14
Identities = 58/226 (25%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175
C +C L C H C+ CL+ Y ++I + +V ++CPE C P +
Sbjct: 94 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153
Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235
+ L+ + L +Y+ +L+ L D +CP P C V+ C C C
Sbjct: 154 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGIC--SSCNF 208
Query: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------E 277
FC C+ +H C + ++ R + L+ K YG+ +
Sbjct: 209 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 268
Query: 278 SGPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 323
+ K CP C I K++ CN MTC C FCW+CM +S
Sbjct: 269 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 312
>gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 77.8 bits (190), Expect = 3e-14
Identities = 58/226 (25%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175
C +C L C H C+ CL+ Y ++I + +V ++CPE C P +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235
+ L+ + L +Y+ +L+ L D +CP P C V+ C C C
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGIC--SSCNF 334
Query: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------E 277
FC C+ +H C + ++ R + L+ K YG+ +
Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394
Query: 278 SGPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 323
+ K CP C I K++ CN MTC C FCW+CM +S
Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438
>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1
isoform 1 [Homo sapiens]
Length = 468
Score = 69.3 bits (168), Expect = 1e-11
Identities = 85/333 (25%), Positives = 111/333 (33%), Gaps = 96/333 (28%)
Query: 55 EPPPPAAQPPPAPA---PAAAQGPPPEAL----------PAEPAAE----AEAEAAAAAA 97
EP PP P P P A PPP P P E A EA A
Sbjct: 127 EPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPA 186
Query: 98 EPGFDDEEAAEGGGP--------------------------------GAEEVECPLCLVR 125
D+EE A G E ECP+C
Sbjct: 187 SYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSV 246
Query: 126 LPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCP------ECSERLNPHDIRLLL 179
L P A L C H CR+CL+ +R + +SCP CS +L +I+ LL
Sbjct: 247 LAPGEAVVLRECLHTFCRECLQGTIR---NSQEAEVSCPFIDNTYSCSGKLLEREIKALL 303
Query: 180 ADPPLMHKYEEFM-----------LRRYLASDPDCR-WCPAPDCGYAVIAYGCASCPKLT 227
Y+ F+ Y PDC+ WC D V + C C +
Sbjct: 304 TP----EDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED---DVNEFTCPVCFHVN 356
Query: 228 CEREGCQTEFCYHCKQIWHPNQTCDMARQQ---RAQTLRVRTKHTSGLSYGQESGPADDI 284
C CK I H C ++ RAQ + T L + G A
Sbjct: 357 ----------CLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEA--- 402
Query: 285 KPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWL 317
CP+C +++ DG C+ + C VC E CW+
Sbjct: 403 MRCPQCQ-IVVQKKDG-CDWIRCTVCHTEICWV 433
>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
isoform 2 [Homo sapiens]
Length = 510
Score = 69.3 bits (168), Expect = 1e-11
Identities = 85/333 (25%), Positives = 111/333 (33%), Gaps = 96/333 (28%)
Query: 55 EPPPPAAQPPPAPA---PAAAQGPPPEAL----------PAEPAAE----AEAEAAAAAA 97
EP PP P P P A PPP P P E A EA A
Sbjct: 169 EPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPA 228
Query: 98 EPGFDDEEAAEGGGP--------------------------------GAEEVECPLCLVR 125
D+EE A G E ECP+C
Sbjct: 229 SYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSV 288
Query: 126 LPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCP------ECSERLNPHDIRLLL 179
L P A L C H CR+CL+ +R + +SCP CS +L +I+ LL
Sbjct: 289 LAPGEAVVLRECLHTFCRECLQGTIR---NSQEAEVSCPFIDNTYSCSGKLLEREIKALL 345
Query: 180 ADPPLMHKYEEFM-----------LRRYLASDPDCR-WCPAPDCGYAVIAYGCASCPKLT 227
Y+ F+ Y PDC+ WC D V + C C +
Sbjct: 346 TP----EDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED---DVNEFTCPVCFHVN 398
Query: 228 CEREGCQTEFCYHCKQIWHPNQTCDMARQQ---RAQTLRVRTKHTSGLSYGQESGPADDI 284
C CK I H C ++ RAQ + T L + G A
Sbjct: 399 ----------CLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEA--- 444
Query: 285 KPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWL 317
CP+C +++ DG C+ + C VC E CW+
Sbjct: 445 MRCPQCQ-IVVQKKDG-CDWIRCTVCHTEICWV 475
>gi|109150431 ring finger protein 31 [Homo sapiens]
Length = 1072
Score = 67.8 bits (164), Expect = 3e-11
Identities = 68/285 (23%), Positives = 101/285 (35%), Gaps = 52/285 (18%)
Query: 118 ECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCPECSERLNPHDIR 176
EC +C LP R L SC C DC R + + + E + + CP C D +
Sbjct: 698 ECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQ 757
Query: 177 LL------------LADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGC-ASC 223
LL +P + + + L DP WC G+ A+C
Sbjct: 758 LLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQCSFGFIYEREQLEATC 817
Query: 224 PKLTCEREGCQTEFCYHCKQIW---HPNQTCDMARQQRAQTLRVRTKHTSGLS-YGQESG 279
P+ C FC CK+ W H ++C+ Q + + GL+ Y QE+G
Sbjct: 818 PQ-------CHQTFCVRCKRQWEEQHRGRSCE--DFQNWKRMNDPEYQAQGLAMYLQENG 868
Query: 280 PADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEI--------------SDL 325
CP+C + + G C H C C +FC C L
Sbjct: 869 -----IDCPKCK-FSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSL 922
Query: 326 HYLSPSGCTFWGKKPWS--RKKKILWQLGTLIGA--PVGISLIAG 366
H P C F+ + W+ R +K+L + P G + G
Sbjct: 923 HGHHPRDCLFY-LRDWTALRLQKLLQDNNVMFNTEPPAGARAVPG 966
>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
Length = 866
Score = 63.5 bits (153), Expect = 7e-10
Identities = 56/237 (23%), Positives = 96/237 (40%), Gaps = 33/237 (13%)
Query: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPE--CSERLNPH 173
+EC C P E + H C++CL Y + + S ++ +SC E C+
Sbjct: 513 IECRCCYGEFPFEELTQCADA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTS 571
Query: 174 DIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGC 233
++ +L +++KY E +A+ P C + + + + +C C
Sbjct: 572 ELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD--SDVKRFSCPNPHC 628
Query: 234 QTEFCYHCKQIW--HPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCS 291
+ E C C+ +W H TC+ ++ ++ RT +E A I+ C +C
Sbjct: 629 RKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRTSI-------EEKMTAARIRKCHKCG 679
Query: 292 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGCTFW 336
+IK CN M+C CG + C+LC I+ H SP S C+ W
Sbjct: 680 TGLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLW 733
>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
Length = 923
Score = 63.5 bits (153), Expect = 7e-10
Identities = 56/237 (23%), Positives = 96/237 (40%), Gaps = 33/237 (13%)
Query: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPE--CSERLNPH 173
+EC C P E + H C++CL Y + + S ++ +SC E C+
Sbjct: 570 IECRCCYGEFPFEELTQCADA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTS 628
Query: 174 DIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGC 233
++ +L +++KY E +A+ P C + + + + +C C
Sbjct: 629 ELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD--SDVKRFSCPNPHC 685
Query: 234 QTEFCYHCKQIW--HPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCS 291
+ E C C+ +W H TC+ ++ ++ RT +E A I+ C +C
Sbjct: 686 RKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRTSI-------EEKMTAARIRKCHKCG 736
Query: 292 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGCTFW 336
+IK CN M+C CG + C+LC I+ H SP S C+ W
Sbjct: 737 TGLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLW 790
>gi|169790973 parkin isoform 3 [Homo sapiens]
Length = 316
Score = 58.2 bits (139), Expect = 3e-08
Identities = 37/122 (30%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
Query: 206 CPAPDCGYAVIAYGCASCPKLTCERE---GCQTEFCYHCKQIWHPNQTCDMARQQRAQTL 262
CP P CG ++ K+TCE GC FC CK+ +H + + T
Sbjct: 183 CPRPGCGAGLLPE--PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQ 240
Query: 263 RVRTKHTSGLSYGQESGPADDI----KPCPRCSAYIIKMNDGSCNHMTC--AVCGCEFCW 316
R + E+ + I KPCPRC + K +G C HM C C E+CW
Sbjct: 241 AYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEK--NGGCMHMKCPQPQCRLEWCW 298
Query: 317 LC 318
C
Sbjct: 299 NC 300
>gi|169790971 parkin isoform 2 [Homo sapiens]
Length = 437
Score = 58.2 bits (139), Expect = 3e-08
Identities = 37/122 (30%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
Query: 206 CPAPDCGYAVIAYGCASCPKLTCERE---GCQTEFCYHCKQIWHPNQTCDMARQQRAQTL 262
CP P CG ++ K+TCE GC FC CK+ +H + + T
Sbjct: 304 CPRPGCGAGLLPE--PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQ 361
Query: 263 RVRTKHTSGLSYGQESGPADDI----KPCPRCSAYIIKMNDGSCNHMTC--AVCGCEFCW 316
R + E+ + I KPCPRC + K +G C HM C C E+CW
Sbjct: 362 AYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEK--NGGCMHMKCPQPQCRLEWCW 419
Query: 317 LC 318
C
Sbjct: 420 NC 421
>gi|169790969 parkin isoform 1 [Homo sapiens]
Length = 465
Score = 58.2 bits (139), Expect = 3e-08
Identities = 37/122 (30%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
Query: 206 CPAPDCGYAVIAYGCASCPKLTCERE---GCQTEFCYHCKQIWHPNQTCDMARQQRAQTL 262
CP P CG ++ K+TCE GC FC CK+ +H + + T
Sbjct: 332 CPRPGCGAGLLPE--PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQ 389
Query: 263 RVRTKHTSGLSYGQESGPADDI----KPCPRCSAYIIKMNDGSCNHMTC--AVCGCEFCW 316
R + E+ + I KPCPRC + K +G C HM C C E+CW
Sbjct: 390 AYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEK--NGGCMHMKCPQPQCRLEWCW 447
Query: 317 LC 318
C
Sbjct: 448 NC 449
>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
Length = 835
Score = 57.8 bits (138), Expect = 4e-08
Identities = 43/126 (34%), Positives = 54/126 (42%), Gaps = 21/126 (16%)
Query: 60 AAQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEV-- 117
AA P P +A G E P+A A A A+AAA+ P GGG A E+
Sbjct: 15 AASGSPGPGEGSAGG---EKRSTAPSAAASASASAAASSPA--------GGGAEALELLE 63
Query: 118 ECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES--------RVPISCPECSER 169
C +C RL PER PRLL C H +C CL + S + CP C ++
Sbjct: 64 HCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQ 123
Query: 170 LNPHDI 175
DI
Sbjct: 124 CFSKDI 129
>gi|22749145 ring finger protein 217 [Homo sapiens]
Length = 275
Score = 54.7 bits (130), Expect = 3e-07
Identities = 49/198 (24%), Positives = 80/198 (40%), Gaps = 28/198 (14%)
Query: 152 LEISESRVPISCP--ECSERLNPHDIRLLLADPPLMHKYEEFM-LRRYLASDPDCRWCPA 208
+++ +V I CP EC E L + L + KY+ F+ L R +S C C
Sbjct: 1 MKVQLGQVEIKCPITECFEFLEETTVVYNLTHEDSI-KYKYFLELGRIDSSTKPCPQCKH 59
Query: 209 ----PDCGYAVIAYGCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRV 264
G+ S K+ C CQ +C+ C WH C ++ + ++
Sbjct: 60 FTTFKKKGHIPTPSRSESKYKIQCPT--CQFVWCFKCHSPWHEGVNC----KEYKKGDKL 113
Query: 265 RTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD 324
S + +GQ + + CP+C +I + C+HMTC+ C FC+ C +
Sbjct: 114 LRHWASEIEHGQRNA-----QKCPKCKIHIQRTE--GCDHMTCSQCNTNFCYRCGERYRQ 166
Query: 325 LHY-------LSPSGCTF 335
L + LS GC +
Sbjct: 167 LRFFGDHTSNLSIFGCKY 184
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 50.4 bits (119), Expect = 6e-06
Identities = 41/102 (40%), Positives = 47/102 (46%), Gaps = 5/102 (4%)
Query: 33 LTLHSVFSASARGRRARAKPQ-AEPPPPAAQPPPA-PAPAAAQGPPPEALPAEPAAEAEA 90
+ L + ASA A +P AE P QPPPA APA Q PP E PAE A
Sbjct: 593 IQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE-VQPPPA 651
Query: 91 EAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAP 132
E A A +P +E AE P AE E P + LP E P
Sbjct: 652 EEAPAEVQPPPAEEAPAEVQPPPAE--EAPAEVQSLPAEETP 691
Score = 40.8 bits (94), Expect = 0.005
Identities = 32/73 (43%), Positives = 32/73 (43%), Gaps = 12/73 (16%)
Query: 48 ARAKPQAEPPPPAA------QPPPA-PAPAAAQGPPPEALPAE----PAAEAEAEAAAAA 96
A P PPPA QPPPA APA Q PP E PAE PA E E AA
Sbjct: 639 AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAA 698
Query: 97 A-EPGFDDEEAAE 108
P DD A E
Sbjct: 699 VHSPPADDVPAEE 711
Score = 31.2 bits (69), Expect = 3.6
Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 60 AAQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEE 116
A + P AP Q P P+ AE A+ AE + AA P DE AE P +EE
Sbjct: 445 AMETPAEEAPTEFQSPLPKETTAEEAS-AEIQLLAATEPPA--DETPAEARSPLSEE 498
>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
Length = 1006
Score = 50.1 bits (118), Expect = 7e-06
Identities = 52/185 (28%), Positives = 69/185 (37%), Gaps = 27/185 (14%)
Query: 2 GSEKDSESPRSTSLHAAAPDPK---CRSGG----RRRRLTLHSVFSASARGRRARAKPQA 54
GSE S+SP S S+ A DP C + R T+H + ++R +P A
Sbjct: 662 GSE-GSQSPGS-SVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAA 719
Query: 55 EPPPPAAQPPPAPAPA---------------AAQGPPPEALPAEPAAEAEAEAAAAAAEP 99
P PP PPAP+PA AA PPP PA E+ + + + P
Sbjct: 720 PPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGP 779
Query: 100 GFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV 159
G A GP A+ R P AP + C C + LE +
Sbjct: 780 GL---APARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHK 836
Query: 160 PISCP 164
SCP
Sbjct: 837 KYSCP 841
Score = 36.2 bits (82), Expect = 0.11
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 43 ARGRRARAKPQAEPPPPAAQPPPAPAPAAAQGPPPEALPA 82
+RG R P+ + PPP P PA AP A PPP A P+
Sbjct: 914 SRGPRDGLGPEPQEPPPGPPPSPAAAPEAV--PPPPAPPS 951
Score = 34.3 bits (77), Expect = 0.42
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 12/73 (16%)
Query: 53 QAEPPPPAAQPPPAPAPAAAQGPP-----PEALPAEPAAEAEAEAAAAAAEPGFDDEEAA 107
+A PAA+ P AP P A+ PP P+A + P A E A AA P E+ A
Sbjct: 604 RAPEDAPAARRPKAP-PGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATP----EDGA 658
Query: 108 EGGGPGAEEVECP 120
GG G+E + P
Sbjct: 659 --GGRGSEGSQSP 669
Score = 32.0 bits (71), Expect = 2.1
Identities = 29/98 (29%), Positives = 36/98 (36%), Gaps = 23/98 (23%)
Query: 50 AKPQAEPPPPAAQ-PPPAPAPAAAQGP---------------PPEALPAEPAAEAEAEAA 93
A P E PA + P PAPAPAA+ P PP P PAA EA
Sbjct: 886 AGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEA-VP 944
Query: 94 AAAAEPGFDDE------EAAEGGGPGAEEVECPLCLVR 125
A P + D+ + P C LC ++
Sbjct: 945 PPPAPPSYSDKGVQTPSKGTPAPLPNGNHRYCRLCNIK 982
>gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo
sapiens]
Length = 282
Score = 49.3 bits (116), Expect = 1e-05
Identities = 48/188 (25%), Positives = 68/188 (36%), Gaps = 41/188 (21%)
Query: 56 PPPPAAQPPPAPAPAAAQGPPPEALPAEPAAEAE-AEAAAAAAEPGFDDEEAAEGGGPGA 114
P P A PPAP + P P++ A P E + + E D ++AE G P
Sbjct: 11 PLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQGDPAG 70
Query: 115 E--EVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNP 172
E EV C CL +A +SC C+ +Y C E L P
Sbjct: 71 EGKEVLCDFCLDDTRRVKAV-------KSCLTCMVNY----------------CEEHLQP 107
Query: 173 HDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREG 232
H + + L L D + R+CPA ++ ++ C CP C +
Sbjct: 108 HQVNIKLQSHLLTEP----------VKDHNWRYCPA---HHSPLSAFC--CPDQQCICQD 152
Query: 233 CQTEFCYH 240
C E H
Sbjct: 153 CCQEHSGH 160
>gi|48255913 tripartite motif-containing 16 [Homo sapiens]
Length = 564
Score = 49.3 bits (116), Expect = 1e-05
Identities = 48/188 (25%), Positives = 68/188 (36%), Gaps = 41/188 (21%)
Query: 56 PPPPAAQPPPAPAPAAAQGPPPEALPAEPAAEAE-AEAAAAAAEPGFDDEEAAEGGGPGA 114
P P A PPAP + P P++ A P E + + E D ++AE G P
Sbjct: 11 PLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQGDPAG 70
Query: 115 E--EVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNP 172
E EV C CL +A +SC C+ +Y C E L P
Sbjct: 71 EGKEVLCDFCLDDTRRVKAV-------KSCLTCMVNY----------------CEEHLQP 107
Query: 173 HDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREG 232
H + + L L D + R+CPA ++ ++ C CP C +
Sbjct: 108 HQVNIKLQSHLLTEP----------VKDHNWRYCPA---HHSPLSAFC--CPDQQCICQD 152
Query: 233 CQTEFCYH 240
C E H
Sbjct: 153 CCQEHSGH 160
>gi|239753500 PREDICTED: hypothetical protein [Homo sapiens]
Length = 213
Score = 47.4 bits (111), Expect = 5e-05
Identities = 37/103 (35%), Positives = 44/103 (42%), Gaps = 17/103 (16%)
Query: 44 RGRRARAKPQAEPPPPAAQPPPAPAPAAAQGPPPEALPAEPAAEAEAE----AAAAAAEP 99
RG RA + PA PPAP P + P P A EPAA A AAA+A
Sbjct: 2 RGLRASGASPSPRSSPARSHPPAPLPFPERLPRPAA--KEPAARTPARQVFPAAASAGRE 59
Query: 100 GFDDEEAAEGGGPG---AEEVECPLCLVRLPPERAPRLLSCPH 139
G + A G PG + E+ PP RAPR + PH
Sbjct: 60 GSAAPDGARGSTPGLAASRELS--------PPPRAPRTVPAPH 94
Score = 30.0 bits (66), Expect = 8.0
Identities = 33/119 (27%), Positives = 40/119 (33%), Gaps = 24/119 (20%)
Query: 18 AAPDPKCRSGGRRRRLTLHSVFSASAR-GRRARAKP--------------QAEPPPPAAQ 62
AA +P R+ R+ VF A+A GR A P + PPP A +
Sbjct: 36 AAKEPAARTPARQ-------VFPAAASAGREGSAAPDGARGSTPGLAASRELSPPPRAPR 88
Query: 63 PPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPL 121
PAP P + P A P EPG E A P CPL
Sbjct: 89 TVPAPHPRLSPARRPGAEPENKFVALRGSHKTRNREPGMLRE--AFKSAPPTGSGYCPL 145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,022,032
Number of Sequences: 37866
Number of extensions: 1990896
Number of successful extensions: 40388
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 666
Number of HSP's successfully gapped in prelim test: 1143
Number of HSP's that attempted gapping in prelim test: 20793
Number of HSP's gapped (non-prelim): 13108
length of query: 732
length of database: 18,247,518
effective HSP length: 110
effective length of query: 622
effective length of database: 14,082,258
effective search space: 8759164476
effective search space used: 8759164476
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.