BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [Homo sapiens] (1016 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [H... 2034 0.0 gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens] 79 2e-14 gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens] 79 2e-14 gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens] 77 6e-14 gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor ... 75 2e-13 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 44 6e-04 gi|156104891 general transcription factor IIF, polypeptide 1, 74... 44 6e-04 gi|217330641 IWS1 homolog [Homo sapiens] 44 8e-04 gi|58761548 tau tubulin kinase 1 [Homo sapiens] 44 0.001 gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 44 0.001 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 43 0.002 gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens] 42 0.003 gi|74325776 MACRO domain containing 2 isoform 2 [Homo sapiens] 42 0.003 gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 42 0.004 gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 42 0.004 gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 42 0.004 gi|168229156 NFKB activating protein [Homo sapiens] 41 0.005 gi|55741677 SET domain containing 1A [Homo sapiens] 40 0.009 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 40 0.009 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 40 0.015 gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 39 0.019 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 39 0.019 gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 39 0.019 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 39 0.025 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 39 0.025 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 39 0.025 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 39 0.025 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 39 0.025 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 39 0.025 gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 39 0.025 >gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [Homo sapiens] Length = 1016 Score = 2035 bits (5271), Expect = 0.0 Identities = 1016/1016 (100%), Positives = 1016/1016 (100%) Query: 1 MSQGPPTGESSEPEAKVLHTKRLYRAVVEAVHRLDLILCNKTAYQEVFKPENISLRNKLR 60 MSQGPPTGESSEPEAKVLHTKRLYRAVVEAVHRLDLILCNKTAYQEVFKPENISLRNKLR Sbjct: 1 MSQGPPTGESSEPEAKVLHTKRLYRAVVEAVHRLDLILCNKTAYQEVFKPENISLRNKLR 60 Query: 61 ELCVKLMFLHPVDYGRKAEELLWRKVYYEVIQLIKTNKKHIHSRSTLECAYRTHLVAGIG 120 ELCVKLMFLHPVDYGRKAEELLWRKVYYEVIQLIKTNKKHIHSRSTLECAYRTHLVAGIG Sbjct: 61 ELCVKLMFLHPVDYGRKAEELLWRKVYYEVIQLIKTNKKHIHSRSTLECAYRTHLVAGIG 120 Query: 121 FYQHLLLYIQSHYQLELQCCIDWTHVTDPLIGCKKPVSASGKEMDWAQMACHRCLVYLGD 180 FYQHLLLYIQSHYQLELQCCIDWTHVTDPLIGCKKPVSASGKEMDWAQMACHRCLVYLGD Sbjct: 121 FYQHLLLYIQSHYQLELQCCIDWTHVTDPLIGCKKPVSASGKEMDWAQMACHRCLVYLGD 180 Query: 181 LSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLAGSKYYNVEAMYCYLRCIQ 240 LSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLAGSKYYNVEAMYCYLRCIQ Sbjct: 181 LSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLAGSKYYNVEAMYCYLRCIQ 240 Query: 241 SEVSFEGAYGNLKRLYDKAAKMYHQLKKCETRKLSPGKKRCKDIKRLLVNFMYLQSLLQP 300 SEVSFEGAYGNLKRLYDKAAKMYHQLKKCETRKLSPGKKRCKDIKRLLVNFMYLQSLLQP Sbjct: 241 SEVSFEGAYGNLKRLYDKAAKMYHQLKKCETRKLSPGKKRCKDIKRLLVNFMYLQSLLQP 300 Query: 301 KSSSVDSELTSLCQSVLEDFNLCLFYLPSSPNLSLASEDEEEYESGYAFLPDLLIFQMVI 360 KSSSVDSELTSLCQSVLEDFNLCLFYLPSSPNLSLASEDEEEYESGYAFLPDLLIFQMVI Sbjct: 301 KSSSVDSELTSLCQSVLEDFNLCLFYLPSSPNLSLASEDEEEYESGYAFLPDLLIFQMVI 360 Query: 361 ICLMCVHSLERAGSKQYSAAIAFTLALFSHLVNHVNIRLQAELEEGENPVPAFQSDGTDE 420 ICLMCVHSLERAGSKQYSAAIAFTLALFSHLVNHVNIRLQAELEEGENPVPAFQSDGTDE Sbjct: 361 ICLMCVHSLERAGSKQYSAAIAFTLALFSHLVNHVNIRLQAELEEGENPVPAFQSDGTDE 420 Query: 421 PESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFES 480 PESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFES Sbjct: 421 PESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFES 480 Query: 481 DSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLE 540 DSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLE Sbjct: 481 DSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLE 540 Query: 541 PPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQPTTNPHT 600 PPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQPTTNPHT Sbjct: 541 PPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQPTTNPHT 600 Query: 601 SASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERSIQEKLQVLMAEGLLPAVKV 660 SASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERSIQEKLQVLMAEGLLPAVKV Sbjct: 601 SASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERSIQEKLQVLMAEGLLPAVKV 660 Query: 661 FLDWLRTNPDLIIVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDLLEGCELP 720 FLDWLRTNPDLIIVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDLLEGCELP Sbjct: 661 FLDWLRTNPDLIIVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDLLEGCELP 720 Query: 721 DLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESVVRICCIRSFGHFIARLQ 780 DLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESVVRICCIRSFGHFIARLQ Sbjct: 721 DLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESVVRICCIRSFGHFIARLQ 780 Query: 781 GSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEEARRNRLMRDMAQLRLQLEVSQL 840 GSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEEARRNRLMRDMAQLRLQLEVSQL Sbjct: 781 GSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEEARRNRLMRDMAQLRLQLEVSQL 840 Query: 841 EGSLQQPKAQSAMSPYLVPDTQALCHHLPVIRQLATSGRFIVIIPRTVIDGLDLLKKEHP 900 EGSLQQPKAQSAMSPYLVPDTQALCHHLPVIRQLATSGRFIVIIPRTVIDGLDLLKKEHP Sbjct: 841 EGSLQQPKAQSAMSPYLVPDTQALCHHLPVIRQLATSGRFIVIIPRTVIDGLDLLKKEHP 900 Query: 901 GARDGIRYLEAEFKKGNRYIRCQKEVGKSFERHKLKRQDADAWTLYKILDSCKQLTLAQG 960 GARDGIRYLEAEFKKGNRYIRCQKEVGKSFERHKLKRQDADAWTLYKILDSCKQLTLAQG Sbjct: 901 GARDGIRYLEAEFKKGNRYIRCQKEVGKSFERHKLKRQDADAWTLYKILDSCKQLTLAQG 960 Query: 961 AGEEDPSGMVTIITGLPLDNPSVLSGPMQAALQAAAHASVDIKNVLDFYKQWKEIG 1016 AGEEDPSGMVTIITGLPLDNPSVLSGPMQAALQAAAHASVDIKNVLDFYKQWKEIG Sbjct: 961 AGEEDPSGMVTIITGLPLDNPSVLSGPMQAALQAAAHASVDIKNVLDFYKQWKEIG 1016 >gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens] Length = 1137 Score = 79.0 bits (193), Expect = 2e-14 Identities = 62/225 (27%), Positives = 106/225 (47%), Gaps = 29/225 (12%) Query: 56 RNKLRELCVKLMFLHPVDYG--RKAEELLWRKVYYEVIQLIKTNKKHIHS--RSTLECAY 111 R L++L K M + ++Y +K E+ LW + I ++ K+ + RS ++ Sbjct: 33 RQALQDLYQK-MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANL 91 Query: 112 RTHLVAGIGFYQHLLLYIQSHYQLELQCCIDWTHV---------TDPLIGCKKPVSASGK 162 L A GFY LL + + + ++L C + + + T ++ KP S+S Sbjct: 92 SLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIV---KPQSSS-- 146 Query: 163 EMDWAQMACHRCLVYLGDLSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLA 222 C CLV+LGD++RY+N+ + AE +Y A + P G P+NQL LA Sbjct: 147 ----CSYICQHCLVHLGDIARYRNQTSQ------AESYYRHAAQLVPSNGQPYNQLAILA 196 Query: 223 GSKYYNVEAMYCYLRCIQSEVSFEGAYGNLKRLYDKAAKMYHQLK 267 SK ++ ++ Y R I + F A NL++ KA + ++K Sbjct: 197 SSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVK 241 Score = 41.6 bits (96), Expect = 0.004 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 24/168 (14%) Query: 655 LPAVKVFLDWLRTNPDLI-IVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDL 713 LPAVKV +DWLR P + Q +W L LLN + P +DL Sbjct: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLN-------------SFHPHEEDL 407 Query: 714 LEGCELPDLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESV---VRICCIR 770 P LPE+ L+ LR + R +F ++ +E +R + Sbjct: 408 SSISATP-------LPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLI 460 Query: 771 SFGHFIARLQGSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEE 818 S G +IA Q ++Q EVG + I + + L ++A+ + +E Sbjct: 461 SIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQE 508 >gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens] Length = 1091 Score = 79.0 bits (193), Expect = 2e-14 Identities = 62/225 (27%), Positives = 106/225 (47%), Gaps = 29/225 (12%) Query: 56 RNKLRELCVKLMFLHPVDYG--RKAEELLWRKVYYEVIQLIKTNKKHIHS--RSTLECAY 111 R L++L K M + ++Y +K E+ LW + I ++ K+ + RS ++ Sbjct: 33 RQALQDLYQK-MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANL 91 Query: 112 RTHLVAGIGFYQHLLLYIQSHYQLELQCCIDWTHV---------TDPLIGCKKPVSASGK 162 L A GFY LL + + + ++L C + + + T ++ KP S+S Sbjct: 92 SLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIV---KPQSSS-- 146 Query: 163 EMDWAQMACHRCLVYLGDLSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLA 222 C CLV+LGD++RY+N+ + AE +Y A + P G P+NQL LA Sbjct: 147 ----CSYICQHCLVHLGDIARYRNQTSQ------AESYYRHAAQLVPSNGQPYNQLAILA 196 Query: 223 GSKYYNVEAMYCYLRCIQSEVSFEGAYGNLKRLYDKAAKMYHQLK 267 SK ++ ++ Y R I + F A NL++ KA + ++K Sbjct: 197 SSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVK 241 Score = 41.6 bits (96), Expect = 0.004 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 24/168 (14%) Query: 655 LPAVKVFLDWLRTNPDLI-IVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDL 713 LPAVKV +DWLR P + Q +W L LLN + P +DL Sbjct: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLN-------------SFHPHEEDL 407 Query: 714 LEGCELPDLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESV---VRICCIR 770 P LPE+ L+ LR + R +F ++ +E +R + Sbjct: 408 SSISATP-------LPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLI 460 Query: 771 SFGHFIARLQGSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEE 818 S G +IA Q ++Q EVG + I + + L ++A+ + +E Sbjct: 461 SIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQE 508 >gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens] Length = 1049 Score = 77.4 bits (189), Expect = 6e-14 Identities = 56/203 (27%), Positives = 95/203 (46%), Gaps = 26/203 (12%) Query: 76 RKAEELLWRKVYYEVIQLIKTNKKHIHS--RSTLECAYRTHLVAGIGFYQHLLLYIQSHY 133 +K E+ LW + I ++ K+ + RS ++ L A GFY LL + + + Sbjct: 12 KKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVF 71 Query: 134 QLELQCCIDWTHV---------TDPLIGCKKPVSASGKEMDWAQMACHRCLVYLGDLSRY 184 ++L C + + + T ++ KP S+S C CLV+LGD++RY Sbjct: 72 NVDLPCRVKSSQLGIISNKQTHTSAIV---KPQSSS------CSYICQHCLVHLGDIARY 122 Query: 185 QNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLAGSKYYNVEAMYCYLRCIQSEVS 244 +N+ + AE +Y A + P G P+NQL LA SK ++ ++ Y R I + Sbjct: 123 RNQTSQ------AESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFP 176 Query: 245 FEGAYGNLKRLYDKAAKMYHQLK 267 F A NL++ KA + ++K Sbjct: 177 FPAASTNLQKALSKALESRDEVK 199 Score = 41.6 bits (96), Expect = 0.004 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 24/168 (14%) Query: 655 LPAVKVFLDWLRTNPDLI-IVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDL 713 LPAVKV +DWLR P + Q +W L LLN + P +DL Sbjct: 319 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLN-------------SFHPHEEDL 365 Query: 714 LEGCELPDLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESV---VRICCIR 770 P LPE+ L+ LR + R +F ++ +E +R + Sbjct: 366 SSISATP-------LPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLI 418 Query: 771 SFGHFIARLQGSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEE 818 S G +IA Q ++Q EVG + I + + L ++A+ + +E Sbjct: 419 SIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQE 466 >gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor [Homo sapiens] Length = 1419 Score = 75.5 bits (184), Expect = 2e-13 Identities = 64/281 (22%), Positives = 132/281 (46%), Gaps = 20/281 (7%) Query: 9 ESSEPEAKVLHTKRLYRAVVEAVHRLDLILCNKTAYQEVFKPENISLRNKLRELCVKLM- 67 E E + L + L+R ++ +L L N + + PE + +LR ++L Sbjct: 567 EEVEQHMRNLQQQELHR-LLRVADNQELQLSNLLSRDRI-SPEGLEKMAQLRAELLQLYE 624 Query: 68 --FLHPVDYG--RKAEELLWRKVYYEVIQLIKTNKK--HIHSRSTLECAYRTHLVAGIGF 121 L +++ + +++LW+ +Y+VI+ + K ++ + + L G F Sbjct: 625 RCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVKDPNVENPEQIRNRLLELLDEGSDF 684 Query: 122 YQHLLLYIQSHYQLELQCCIDWTHVTDPLIGCKKPVSASGKEMDWAQMACHRCLVYLGDL 181 + LL +Q Y+ +L+ +D + KP+ K + +A ++ RC++ GD+ Sbjct: 685 FDSLLQKLQVTYKFKLEDYMDGLAIRS------KPLR---KTVKYALISAQRCMICQGDI 735 Query: 182 SRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLAGSKYYNVEAMYCYLRCIQS 241 +RY+ + + A +Y +A +AP+ G P+NQL LA ++A+Y Y+R + + Sbjct: 736 ARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTRRKLDAVYYYMRSLAA 795 Query: 242 EVSFEGAYGNLKRLYDKAAKMYHQLKKCETRK--LSPGKKR 280 A +L L+++ + Q++K + + LSP + R Sbjct: 796 SNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWR 836 Score = 59.7 bits (143), Expect = 1e-08 Identities = 132/577 (22%), Positives = 228/577 (39%), Gaps = 103/577 (17%) Query: 422 ESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFESD 481 E+K E+ E+ E ++P + RK +K + RH VGDD+ E + Sbjct: 812 ETKRKAEQMEKKQHEEFDLSPD--QWRKGKKSTF-------RH---VGDDTTRLEIWIHP 859 Query: 482 SSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLEP 541 S R+S+G++SG D E G + + S++N + S L + TR Sbjct: 860 SH---PRSSQGTESGKDSEQENG---LGSLSPSDLNKRFILSFLH-AHGKLFTRIGMETF 912 Query: 542 PRGRSEAPDSLNGPLGPSEASIASN--LQAMSTQMF-----QTKRCFRLAPTFSNLLLQP 594 P + L S + I S LQ M+ MF Q K CF ++Q Sbjct: 913 PAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSEE---CRSVIQE 969 Query: 595 TTNPHTSASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERSIQEKLQVLMAEGL 654 A V E A + S E + ++ I+ V + L Sbjct: 970 QAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQD-------DQDDIKVSSFVPDLKEL 1022 Query: 655 LPAVKVFLDWLRTNPDL-------IIVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALC 707 LP+VKV+ DW+ PD + + + + +W+ L+ N+L A + +S + L Sbjct: 1023 LPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTA---VNQSEVPLY 1079 Query: 708 PEVQDLLEGCELPDLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESVVRIC 767 + D L + L+L ED L PL AA + + ++ + R+ Sbjct: 1080 KDPDDDL---------TLLILEEDRLLSGFVPLLAAPQDPCY-VEKTSDKVIAADCKRVT 1129 Query: 768 CIRSFGHFIARLQGSILQFNPEVGIFVSIA------------------QSEQESLL---- 805 ++ F + + +L F + G +VS+A + E+E ++ Sbjct: 1130 VLKYFLEALCGQEEPLLAF--KGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDF 1187 Query: 806 -QQAQAQFRMAQEEARRNR-----LMRDMAQLRLQLEVSQ--LEGSLQQPKAQSAMSP-Y 856 + ++A+ +++ R R L R +A+ + + E Q LE Q + + + P + Sbjct: 1188 EEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLF 1247 Query: 857 LVPDTQALCHHLPVIRQLATSGRFIVIIPRTVIDGLDLLKK----EHPG----------A 902 LVPDT HL + +L S ++I+++P VI+ LD L K +H A Sbjct: 1248 LVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKA 1307 Query: 903 RDGIRYLEAEFKKGNRYIRCQKEVGKSFERHKLKRQD 939 R I +LE F+ + +R G E + +D Sbjct: 1308 RKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSED 1344 Score = 33.5 bits (75), Expect = 1.0 Identities = 44/169 (26%), Positives = 66/169 (39%), Gaps = 16/169 (9%) Query: 400 QAELEEGENPVPAFQSDGTDEPESKEPVEKEE---EPDP---EPPPVTPQVG--EGRKSR 451 + E EE N V + +E E + V KEE +PD E P +VG +G K + Sbjct: 162 RVEEEEVLNQVEQLR---VEEDECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGK 218 Query: 452 KFSRLSCLRRRRHPPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAE 511 + + +R P G SD + R S +GS+ S EG G + Sbjct: 219 RMGKGEGVRETHDDPARGRPGSAKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGC 278 Query: 512 TDSEMNSQESRSDLEDMEEEEGTRSPTLEPPRGRSEAPDSLNGPLGPSE 560 + + R L +++ + S T R + PD L GP SE Sbjct: 279 RRRRQDRTKERPRL----KKQVSVSSTDSLDEDRIDEPDGL-GPRRSSE 322 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 44.3 bits (103), Expect = 6e-04 Identities = 38/165 (23%), Positives = 67/165 (40%), Gaps = 8/165 (4%) Query: 471 DSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEE 530 DSD S+ SDSS + S S SD S + +DS+ +S +S SD D + Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638 Query: 531 EEGTRSPTLEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNL 590 + + S++ DS N S++S +S+ S+ + + + Sbjct: 639 KSDSSDSNSSDSSDNSDSSDSSNSS-NSSDSSDSSDSSDSSSSSDSSN-------SSDSS 690 Query: 591 LLQPTTNPHTSASHRPCVNGDVDKPSEPASEEGSESEGSESSGRS 635 ++N S+ + D S+ ++ S+S+ S SS S Sbjct: 691 DSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735 Score = 44.3 bits (103), Expect = 6e-04 Identities = 49/237 (20%), Positives = 85/237 (35%), Gaps = 13/237 (5%) Query: 415 SDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDL 474 SD +D +S + + D + + S S S D SD Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812 Query: 475 SEGFESDSSH--------DSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLE 526 S+ +SDSS+ DS+ +S SDS G + + NS +S + Sbjct: 813 SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872 Query: 527 DMEEEEGTRSPTLEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPT 586 + + S S++ DS N S++S +SN + S+ + + + Sbjct: 873 SSNSSDSSDSSDSNESSNSSDSSDSSNS--SDSDSSDSSN-SSDSSDSSNSSDSSESSNS 929 Query: 587 FSNLLLQPTTNPHTSASHRPCVNGDVDKPSEPA--SEEGSESEGSESSGRSCRNERS 641 N ++N S+ N S + S + S+S S+SS S ++ S Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS 986 Score = 42.7 bits (99), Expect = 0.002 Identities = 29/139 (20%), Positives = 53/139 (38%) Query: 415 SDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDL 474 SD +D ES + + + D + + S S S D SD Sbjct: 1142 SDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1201 Query: 475 SEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGT 534 S+ +S S DS+ +S+ SDS + D+ S+ + + SD D + + Sbjct: 1202 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDS 1261 Query: 535 RSPTLEPPRGRSEAPDSLN 553 S + + +S++ + N Sbjct: 1262 TSDSNDESDSQSKSGNGNN 1280 Score = 42.0 bits (97), Expect = 0.003 Identities = 43/188 (22%), Positives = 74/188 (39%), Gaps = 17/188 (9%) Query: 470 DDSDLSEGFESDSSHDSARASEGSDSG----------------SDKSLEGGGTAFDAETD 513 D+SD S+ S +S DS+ +S+ SDS S S E ++ +++D Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711 Query: 514 SEMNSQESRSDLEDMEEEEGTRSPTLEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQ 573 S +S S S+ D + + S S++ DS N S++S +SN S Sbjct: 712 SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS-DSSDSSDSSNSSDSSDS 770 Query: 574 MFQTKRCFRLAPTFSNLLLQPTTNPHTSASHRPCVNGDVDKPSEPASEEGSESEGSESSG 633 + + SN + + +S S + D S+ + + S S S +S Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830 Query: 634 RSCRNERS 641 S + S Sbjct: 831 DSSDSSNS 838 Score = 41.6 bits (96), Expect = 0.004 Identities = 48/227 (21%), Positives = 82/227 (36%), Gaps = 10/227 (4%) Query: 415 SDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDL 474 SD ++ +S + + D + + S S S D SD Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078 Query: 475 SEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGT 534 S+ ES S DS+ +S+ SDS + D+ S+ ++ SD D + + Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD--SSDSS 1136 Query: 535 RSPTLEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQP 594 S SE+ DS S++S +S+ S + + S+ Sbjct: 1137 DSSNSSDSSDSSESSDS-------SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1189 Query: 595 TTNPHTSASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERS 641 + + +S S + D S +S+ S+ S+SS S NE S Sbjct: 1190 SDSSDSSDSSDSSDSSD-SSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235 Score = 41.2 bits (95), Expect = 0.005 Identities = 33/120 (27%), Positives = 51/120 (42%), Gaps = 10/120 (8%) Query: 415 SDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDL 474 SD +D +S + + + D + + S S S + D SD Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS 1240 Query: 475 SEGFESDSSHDSARASEGSDSGSD---------KSLEGGGTAFDAETDSE-MNSQESRSD 524 S+ +S +S DS+ +S+ SDS SD KS G D+++DSE +S S SD Sbjct: 1241 SDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300 Score = 40.8 bits (94), Expect = 0.007 Identities = 30/152 (19%), Positives = 56/152 (36%) Query: 415 SDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDL 474 SD +D +S + + + D + + S S S + D SD Sbjct: 1097 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDS 1156 Query: 475 SEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGT 534 S+ +S S DS+ +S+ SDS + + D+ S+ + SD D + + Sbjct: 1157 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1216 Query: 535 RSPTLEPPRGRSEAPDSLNGPLGPSEASIASN 566 + S + + S++S +SN Sbjct: 1217 SDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248 Score = 40.0 bits (92), Expect = 0.011 Identities = 35/172 (20%), Positives = 67/172 (38%), Gaps = 17/172 (9%) Query: 470 DDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDME 529 D SD S +S +S DS+ +S+ SDS S S + ++ +++ +S +S + Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005 Query: 530 EEEGTRSPTLEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSN 589 + + S S + DS N S++S +S+ S + Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNS----SDSSDSSDSSDSSDSSDSSDS---------- 1051 Query: 590 LLLQPTTNPHTSASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERS 641 ++N S+ + S +S+ S+ S+SS S ++ S Sbjct: 1052 ---SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100 Score = 39.3 bits (90), Expect = 0.019 Identities = 34/172 (19%), Positives = 66/172 (38%), Gaps = 17/172 (9%) Query: 470 DDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDME 529 D S+ S+ +S +S DS+ +S SD+ + + D+ S + + SD + Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966 Query: 530 EEEGTRSPTLEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSN 589 + + S S++ DS + S++S +SN S + Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSS-DSSDSSDSSNSSDSSDSSDSS------------ 1013 Query: 590 LLLQPTTNPHTSASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERS 641 ++N S++ N S +S+ S+ S+SS S ++ S Sbjct: 1014 ----DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061 Score = 38.1 bits (87), Expect = 0.042 Identities = 35/151 (23%), Positives = 60/151 (39%), Gaps = 16/151 (10%) Query: 407 ENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPP 466 + P A ++ TD + E +E + +TPQ+ R K + ++ P Sbjct: 182 DGPQVAGSNNSTDNED--EIIENSCRNEGNTSEITPQINSKRNGTKEAEVT--------P 231 Query: 467 KVGDDSDLSEGFESDSSHDSARASEGSDSGS-DKSLEGGGTAFDAETDSEMNSQESRSDL 525 G+D+ L SD S A E D GS D E G D+ +S+ + Sbjct: 232 GTGEDAGLD---NSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKE 288 Query: 526 EDMEEEEGTRSPTLE--PPRGRSEAPDSLNG 554 +D + G S + E P G+ + + ++G Sbjct: 289 DDHDSSIGQNSDSKEYYDPEGKEDPHNEVDG 319 Score = 38.1 bits (87), Expect = 0.042 Identities = 35/172 (20%), Positives = 64/172 (37%), Gaps = 4/172 (2%) Query: 470 DDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDME 529 D SD +G S DS+ +S SDS + + +++DS S SD D + Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDS---SDSDSSDSSDSD 594 Query: 530 EEEGTRSPTLEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSN 589 + + S S++ DS + S++S S + + + + N Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS-KSESDSSDSDSKSDSSDSNSSDSSDN 653 Query: 590 LLLQPTTNPHTSASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERS 641 ++N S+ + S +S S+ S+SS S ++ S Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS 705 Score = 36.6 bits (83), Expect = 0.12 Identities = 48/239 (20%), Positives = 91/239 (38%), Gaps = 29/239 (12%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPE-PPPVTPQVGEGRKSRKFSRLSCLRRRR 463 +G++P + +S+G D+ S+ D + G G S Sbjct: 461 QGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDS------------- 507 Query: 464 HPPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQES-R 522 K +D D ++++S + + G+D +DKS G G + +++DS +S S Sbjct: 508 ---KGAEDDDSDSTSDTNNSDSNGNGNNGNDD-NDKSDSGKGKSDSSDSDSSDSSNSSDS 563 Query: 523 SDLEDMEEEEGTRSPTLEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFR 582 SD D + + S S++ DS + S++S +SN S + Sbjct: 564 SDSSDSDSSDSNSS-------SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616 Query: 583 LAPTFSNLLLQPTTNPHTSASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERS 641 + S ++ + +S + D S +S+ S+ S SS S ++ S Sbjct: 617 SDSSDSK---SDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672 Score = 36.6 bits (83), Expect = 0.12 Identities = 26/114 (22%), Positives = 42/114 (36%), Gaps = 1/114 (0%) Query: 415 SDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDL 474 SD +D +S + + + D + + S S S D SD Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDS 1246 Query: 475 SEGFES-DSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLED 527 S +S DSS S S+ +D +S G G +++DS+ +S D Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300 Score = 36.2 bits (82), Expect = 0.16 Identities = 36/171 (21%), Positives = 67/171 (39%), Gaps = 25/171 (14%) Query: 471 DSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEE 530 DS+ S+ ++ S DS+ +S SDS SD S + D+ + S+ ++ SD D Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDS-SDSS-----DSSDSSSSSDSSNSSDSSDSSDSSN 697 Query: 531 EEGTRSPTLEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNL 590 + + S++ DS N S++S +S+ S Sbjct: 698 SSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS----------------- 740 Query: 591 LLQPTTNPHTSASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERS 641 +++ S++ + S +S+ S+ S+SS S N+ S Sbjct: 741 --SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789 Score = 35.8 bits (81), Expect = 0.21 Identities = 28/123 (22%), Positives = 47/123 (38%), Gaps = 1/123 (0%) Query: 415 SDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDL 474 SD +D S + + + D + + S S S D SD Sbjct: 1172 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231 Query: 475 SEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDME-EEEG 533 +E +S S DS+ +S SDS + + E+DS+ S ++ D + + EG Sbjct: 1232 NESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEG 1291 Query: 534 TRS 536 + S Sbjct: 1292 SDS 1294 Score = 35.4 bits (80), Expect = 0.27 Identities = 34/163 (20%), Positives = 70/163 (42%), Gaps = 2/163 (1%) Query: 479 ESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPT 538 ++D S S+ SDS S S ++ +++DS ++ S SD D + + + S + Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDS 595 Query: 539 LEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQPTTNP 598 + S++ DS + S++S +S+ ++ S++ S+ +++ Sbjct: 596 SDSSNS-SDSSDSSDSS-DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN 653 Query: 599 HTSASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERS 641 S+ N S +S+ S S+ S SS S ++ S Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696 Score = 31.6 bits (70), Expect = 4.0 Identities = 27/124 (21%), Positives = 47/124 (37%), Gaps = 4/124 (3%) Query: 415 SDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDL 474 SD ++ +S + + + D + + S S S D ++ Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234 Query: 475 SEGFESDSSHDSARASEGSDSG-SDKSLEGGGTAFDAETDS---EMNSQESRSDLEDMEE 530 S+ +S S DS+ +S+ SDS S S D+++ S N +S SD E + Sbjct: 1235 SDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDS 1294 Query: 531 EEGT 534 T Sbjct: 1295 NHST 1298 >gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa [Homo sapiens] Length = 517 Score = 44.3 bits (103), Expect = 6e-04 Identities = 50/192 (26%), Positives = 83/192 (43%), Gaps = 19/192 (9%) Query: 391 LVNHVNIRLQAELEEGENPVPAFQSDGTDEPESKE----PVEKEEEPDPEPPPVTPQVGE 446 ++NH +I Q L++ + + + ++ E +E + E + + + G Sbjct: 170 VLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEG- 228 Query: 447 GR--KSRKFSRLSCLRRRRHPPKVGDDSDLS-------EGFESDSSHDSARASEGSDSGS 497 GR K++K + L+ R++ K DD EG E D D + +S+ Sbjct: 229 GRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESK 288 Query: 498 DKS--LEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLEPPRGR---SEAPDSL 552 K+ E G D ++DS S+E + ED EEEE ++PT + + R SE DS Sbjct: 289 AKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSS 348 Query: 553 NGPLGPSEASIA 564 SEAS A Sbjct: 349 EESDIDSEASSA 360 >gi|217330641 IWS1 homolog [Homo sapiens] Length = 819 Score = 43.9 bits (102), Expect = 8e-04 Identities = 52/241 (21%), Positives = 94/241 (39%), Gaps = 17/241 (7%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRH 464 E + P+ SD E ++ E + PP + E ++ S R+ Sbjct: 70 ENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENED-VNQHGSDSESEETRKL 128 Query: 465 PPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSD 524 P ++ +L G SDS ++ SDS ++ + A D+ET+ + Q S S+ Sbjct: 129 PGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKS--PASDSETEDALKPQISDSE 186 Query: 525 LEDMEEEEGTRSPTLEPPRGR---SEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCF 581 E+ + + S EPP+ R SE+ + + SE+ QA ++ + + Sbjct: 187 SEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPK-- 244 Query: 582 RLAPTFSNLLLQPTTNPHTSASHRPCVNGDVDKP--SEPASEEGSESEGSESSGRSCRNE 639 P S+ + S S N ++ KP S+ SE+ ++ S+S Sbjct: 245 ---PRISDSESEDPPRHQASDSE----NEELPKPRISDSESEDPPRNQASDSENEELPKP 297 Query: 640 R 640 R Sbjct: 298 R 298 Score = 38.5 bits (88), Expect = 0.032 Identities = 45/196 (22%), Positives = 79/196 (40%), Gaps = 21/196 (10%) Query: 401 AELEEGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEG--RKSRKFSRLSC 458 ++ E E P P +++P + + E E P+ P V+ EG + S Sbjct: 261 SDSENEELPKPRISDSESEDPPRNQASDSENEELPK-PRVSDSESEGPQKGPASDSETED 319 Query: 459 LRRRRHPPKVGDDSD----------LSEGFESDSSHDSAR-ASEGSDSGSDKSLEGGGTA 507 R + P+ DDSD ++ F SDS D + S S+ K + Sbjct: 320 ASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDE 379 Query: 508 FDAETDSEMNSQESRSDLEDMEEEEGTRSPTLEPPRGRSEAPDS----LNGPLGPSEASI 563 + E + E ++ + L D E+EE + + R S+A DS ++ G E +I Sbjct: 380 DEKEGEEEKVAKRKAAVLSDSEDEE---KASAKKSRVVSDADDSDSDAVSDKSGKREKTI 436 Query: 564 ASNLQAMSTQMFQTKR 579 AS+ + + + K+ Sbjct: 437 ASDSEEEAGKELSDKK 452 Score = 35.4 bits (80), Expect = 0.27 Identities = 37/172 (21%), Positives = 67/172 (38%), Gaps = 17/172 (9%) Query: 398 RLQAELEEGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVT---------PQVGEGR 448 +L E E + SD +E K P E + + P + PQ+ + Sbjct: 127 KLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSE 186 Query: 449 KSRKFSRLSCLRRRRHPPKV----GDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGG 504 + PPK + +L + SDS + + SDS +++ + Sbjct: 187 SEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPK-- 244 Query: 505 GTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLEPPRGRSEAPDSLNGPL 556 D+E++ Q S S+ E++ + + S + +PP R++A DS N L Sbjct: 245 PRISDSESEDPPRHQASDSENEELPKPRISDSESEDPP--RNQASDSENEEL 294 Score = 32.7 bits (73), Expect = 1.8 Identities = 37/188 (19%), Positives = 66/188 (35%), Gaps = 43/188 (22%) Query: 471 DSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEE 530 + D++E + R SE S + L G D+E D +N S S+ E++ Sbjct: 30 EDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHR 89 Query: 531 EEGTRSPT---LEPPRGRSEAPDS-------------------------LNGPLGPSEAS 562 ++ + S + EPP SE D LNG SE Sbjct: 90 QKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENE 149 Query: 563 IASNLQAMSTQMFQTKRCFRLAPTFSNLLLQPTTNPHTSASHRPCVNGDVDKPSEPASEE 622 A +++ + ++ P ++ T + +P ++ + EP + Sbjct: 150 DVGKHPASDSEIEELQK-------------SPASDSETEDALKPQISD--SESEEPPRHQ 194 Query: 623 GSESEGSE 630 S+SE E Sbjct: 195 ASDSENEE 202 >gi|58761548 tau tubulin kinase 1 [Homo sapiens] Length = 1321 Score = 43.5 bits (101), Expect = 0.001 Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 15/136 (11%) Query: 414 QSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSD 473 Q++G +E E +E E+EEE D E + E + + +++ Sbjct: 728 QANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE--------------EEAA 773 Query: 474 LSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEG 533 + S +SEGS+ +D+S EG + A+ E + S +D D+E EEG Sbjct: 774 AAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMAD-GDLEPEEG 832 Query: 534 TRSPTLEPPRGRSEAP 549 +++ L P ++P Sbjct: 833 SKTLVLVSPGDMKKSP 848 >gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] Length = 1163 Score = 43.5 bits (101), Expect = 0.001 Identities = 46/169 (27%), Positives = 74/169 (43%), Gaps = 11/169 (6%) Query: 477 GFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRS 536 G S+ SH + SEG+D+ D S G+ + +DSE S+ S SD E E + + S Sbjct: 408 GSNSEPSHHN---SEGADNSRDDSSSHSGSESSSGSDSE--SESSSSDSEANEPSQ-SAS 461 Query: 537 PTLEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQPTT 596 P EPP D+ + P + S AS++ + K+ R T ++ T+ Sbjct: 462 PEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNS--YTDTS 519 Query: 597 NPHTSASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERSIQEK 645 P ++S P G K + SE G + S + S R++ +K Sbjct: 520 GPKETSSATP---GRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKK 565 Score = 32.0 bits (71), Expect = 3.0 Identities = 30/132 (22%), Positives = 52/132 (39%), Gaps = 8/132 (6%) Query: 476 EGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTR 535 E + + S + GS+ +S G + S +NS SRS D +E R Sbjct: 154 ESYNNSGSSSRKKGQHGSEHSKSRSSSPG----KPQAVSSLNSSHSRSHGNDHHSKEHQR 209 Query: 536 SPTLEPPRGRSEAPDSLNGPLGP-SEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQP 594 S + P ++P + G S S +L + S M Q + + P ++P Sbjct: 210 SKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAY-VRPMDGQESMEP 268 Query: 595 --TTNPHTSASH 604 ++ ++S SH Sbjct: 269 KLSSEHYSSQSH 280 Score = 31.6 bits (70), Expect = 4.0 Identities = 43/218 (19%), Positives = 78/218 (35%), Gaps = 25/218 (11%) Query: 418 TDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDLSEG 477 + + E+ EP + P+PEPPP +L + +P KV S + Sbjct: 448 SSDSEANEP-SQSASPEPEPPPTNKW-----------QLDNWLNKVNPHKVSPASSVDSN 495 Query: 478 FESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSP 537 S + EG + G+ S T+ ET S ++S++ + E G + Sbjct: 496 IPSSQGY----KKEGREQGTGNSYT--DTSGPKETSSATPGRDSKTIQKGSESGRGRQK- 548 Query: 538 TLEPPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQPTTN 597 P + S G P +A A+ + +++ LA + + Sbjct: 549 --SPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPS----SRHK 602 Query: 598 PHTSASHRPCVNGDVDKPSEPASEEGSESEGSESSGRS 635 T S +P + + P +E+ S+SS +S Sbjct: 603 AATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKS 640 Score = 30.8 bits (68), Expect = 6.8 Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 11/88 (12%) Query: 466 PKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDL 525 P S G +S H S R S GS SG++ S G D E+ N+ S S Sbjct: 115 PSTSQSQKRSSGLQS--GHSSQRTSAGSSSGTNSS----GQRHDRES---YNNSGSSSRK 165 Query: 526 EDMEEEEGTRSPTLEPPRGRSEAPDSLN 553 + E ++S + P G+ +A SLN Sbjct: 166 KGQHGSEHSKSRSSSP--GKPQAVSSLN 191 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 42.7 bits (99), Expect = 0.002 Identities = 33/153 (21%), Positives = 65/153 (42%), Gaps = 5/153 (3%) Query: 400 QAELEEGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCL 459 + E + V A +++G +PES++ E E + +P + E K + S Sbjct: 1864 EGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVE 1923 Query: 460 RRRRHPPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSE-MNS 518 G+D SEG E+ + ++A+ +EG + +E +A+ +SE + + Sbjct: 1924 ALETE----GEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEA 1979 Query: 519 QESRSDLEDMEEEEGTRSPTLEPPRGRSEAPDS 551 E + ++ E E S +E P E ++ Sbjct: 1980 LEVEVETQEAEGEAQPESEDVEAPEAEGEMQEA 2012 Score = 37.4 bits (85), Expect = 0.072 Identities = 39/165 (23%), Positives = 69/165 (41%), Gaps = 12/165 (7%) Query: 397 IRLQAELEEGENPVPAFQSDGTDEPESK-EPVEKEEEPDPEPPPVTPQV-GEGRKSRKFS 454 + ++ E +E E +S+ + PE++ E E EEE PE V Q EG ++++ Sbjct: 1980 LEVEVETQEAEGEAQP-ESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVE 2038 Query: 455 RLSCLRRRRHPPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDS 514 + GD S+G E+ + + A+ +EG ++ DA+ ++ Sbjct: 2039 GET-------QKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQ-EA 2090 Query: 515 EMNSQESRSDLEDMEEE-EGTRSPTLEPPRGRSEAPDSLNGPLGP 558 E +Q +E E E E ++ +E P EA G P Sbjct: 2091 EGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAP 2135 Score = 33.1 bits (74), Expect = 1.4 Identities = 39/169 (23%), Positives = 62/169 (36%), Gaps = 17/169 (10%) Query: 400 QAELEEGENPVPAFQSDGTDEPESK--EPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLS 457 +A+ EG + A +++G +PES+ E E E E PE V Q EG + + Sbjct: 2109 EAQKAEG---IEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIE 2165 Query: 458 C----------LRRRRHPPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTA 507 L P G+ SEG E+ + A+ + E Sbjct: 2166 AQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEP 2225 Query: 508 FDAETDSEMNSQESRSDLEDMEEEEGTRSPTLEPPRGRSEAPDSLNGPL 556 ET + S+ E E++G SP + G+SE + P+ Sbjct: 2226 EGVETPEAEGEAQPESEGETQGEKKG--SPQVSLGDGQSEEASESSSPV 2272 Score = 32.0 bits (71), Expect = 3.0 Identities = 49/201 (24%), Positives = 68/201 (33%), Gaps = 41/201 (20%) Query: 400 QAELEEGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPV------------------- 440 +A+ E P + + E E E E EEE PEP V Sbjct: 2188 EAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQG 2247 Query: 441 ----TPQV--GEGRKSRKFSRLSCLRRRR--HPPKVGDDSDLSEGFESDSSHDSARASEG 492 +PQV G+G+ S + R PP G D+ S +S G Sbjct: 2248 EKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWG 2307 Query: 493 S----DSGSDKSL--------EGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLE 540 + DS +D L + GT + M + S S+ E E G+R+P Sbjct: 2308 NCWQKDSENDHVLGDTRSPDAKSTGTPHAERKATRMYPESSTSEQE--EAPLGSRTPEQG 2365 Query: 541 PPRGRSEAPDSLNGPLGPSEA 561 G D G L P+EA Sbjct: 2366 ASEGYDLQEDQALGSLAPTEA 2386 Score = 31.2 bits (69), Expect = 5.2 Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 1/76 (1%) Query: 465 PPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSD 524 P G+ SEG E+ + A+ +EG + +E +A+ +SE + + ++ Sbjct: 1838 PEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESE-DVETPEAE 1896 Query: 525 LEDMEEEEGTRSPTLE 540 E E EG +P E Sbjct: 1897 WEVQPESEGAEAPEAE 1912 >gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens] Length = 425 Score = 42.0 bits (97), Expect = 0.003 Identities = 44/169 (26%), Positives = 69/169 (40%), Gaps = 21/169 (12%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPE---------PPPVTPQVGEGRKSRKFSR 455 E E V + + PE K+ VE+ EE + P P + + E K F++ Sbjct: 247 EEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAK 306 Query: 456 LSCLRRRRHPPKVGD----DSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAE 511 + + +V D D D +G E+DS+ + + S S ++ E DA Sbjct: 307 DENITKGG---EVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAV 363 Query: 512 TDSEMNSQESRSDLEDMEEEEGTRSPTLEPPR--GRSEAPDSLNGPLGP 558 + E ED EE+EG ++P + PR G+SE L GP Sbjct: 364 I---VEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGP 409 >gi|74325776 MACRO domain containing 2 isoform 2 [Homo sapiens] Length = 213 Score = 42.0 bits (97), Expect = 0.003 Identities = 44/169 (26%), Positives = 69/169 (40%), Gaps = 21/169 (12%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPE---------PPPVTPQVGEGRKSRKFSR 455 E E V + + PE K+ VE+ EE + P P + + E K F++ Sbjct: 12 EEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAK 71 Query: 456 LSCLRRRRHPPKVGD----DSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAE 511 + + +V D D D +G E+DS+ + + S S ++ E DA Sbjct: 72 DENITKGG---EVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAV 128 Query: 512 TDSEMNSQESRSDLEDMEEEEGTRSPTLEPPR--GRSEAPDSLNGPLGP 558 + E ED EE+EG ++P + PR G+SE L GP Sbjct: 129 I---VEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGP 174 >gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 41.6 bits (96), Expect = 0.004 Identities = 46/188 (24%), Positives = 73/188 (38%), Gaps = 25/188 (13%) Query: 399 LQAELEEGENPVPAFQSDGTDE-----PESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKF 453 L+ L EG +P S+G ES E E+ E P PP+ + RK Sbjct: 958 LKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFL 1017 Query: 454 SRLSCLRRRRH------PPKVGDDSD-LSEGFE-SDSSHDSARASEGSDSGSDKSLEGGG 505 R +R+R+H + + ++ L E FE SDS R + ++ E Sbjct: 1018 HRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDEN 1077 Query: 506 TAFDAETDSEMNSQE-----------SRSDLEDMEEEEGTRSPTLEPPRGRSEAPDSLNG 554 F E ++SQ+ S+ + ED E ++ +P L+P D N Sbjct: 1078 ELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPV-SLLRKRDVKNS 1136 Query: 555 PLGPSEAS 562 PL P ++ Sbjct: 1137 PLEPDTST 1144 Score = 38.5 bits (88), Expect = 0.032 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 32/154 (20%) Query: 399 LQAELEEGE---------NPVPAFQ---SDGTDEPESKEPVEKEEEPDPEPPPVTPQVGE 446 +QAE EE E + VPA S + E E+KEP +EEE E P V+ + + Sbjct: 1229 MQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEE---EKPRVSEEQRQ 1285 Query: 447 GRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFESDSSHDSARASEGS-DSGSDKSLEGGG 505 + ++ P+ ++ D + + HD+ +G +S K LE Sbjct: 1286 SEEE---------QQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP 1336 Query: 506 TAFDA-------ETDSEMNSQESRSDLEDMEEEE 532 T D E+ + N Q+SR ++D EE E Sbjct: 1337 TREDVKEEPGVQESFLDANMQKSREKIKDKEETE 1370 >gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 41.6 bits (96), Expect = 0.004 Identities = 46/188 (24%), Positives = 73/188 (38%), Gaps = 25/188 (13%) Query: 399 LQAELEEGENPVPAFQSDGTDE-----PESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKF 453 L+ L EG +P S+G ES E E+ E P PP+ + RK Sbjct: 958 LKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFL 1017 Query: 454 SRLSCLRRRRH------PPKVGDDSD-LSEGFE-SDSSHDSARASEGSDSGSDKSLEGGG 505 R +R+R+H + + ++ L E FE SDS R + ++ E Sbjct: 1018 HRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDEN 1077 Query: 506 TAFDAETDSEMNSQE-----------SRSDLEDMEEEEGTRSPTLEPPRGRSEAPDSLNG 554 F E ++SQ+ S+ + ED E ++ +P L+P D N Sbjct: 1078 ELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPV-SLLRKRDVKNS 1136 Query: 555 PLGPSEAS 562 PL P ++ Sbjct: 1137 PLEPDTST 1144 Score = 38.5 bits (88), Expect = 0.032 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 32/154 (20%) Query: 399 LQAELEEGE---------NPVPAFQ---SDGTDEPESKEPVEKEEEPDPEPPPVTPQVGE 446 +QAE EE E + VPA S + E E+KEP +EEE E P V+ + + Sbjct: 1229 MQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEE---EKPRVSEEQRQ 1285 Query: 447 GRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFESDSSHDSARASEGS-DSGSDKSLEGGG 505 + ++ P+ ++ D + + HD+ +G +S K LE Sbjct: 1286 SEEE---------QQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP 1336 Query: 506 TAFDA-------ETDSEMNSQESRSDLEDMEEEE 532 T D E+ + N Q+SR ++D EE E Sbjct: 1337 TREDVKEEPGVQESFLDANMQKSREKIKDKEETE 1370 >gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 41.6 bits (96), Expect = 0.004 Identities = 46/188 (24%), Positives = 73/188 (38%), Gaps = 25/188 (13%) Query: 399 LQAELEEGENPVPAFQSDGTDE-----PESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKF 453 L+ L EG +P S+G ES E E+ E P PP+ + RK Sbjct: 958 LKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFL 1017 Query: 454 SRLSCLRRRRH------PPKVGDDSD-LSEGFE-SDSSHDSARASEGSDSGSDKSLEGGG 505 R +R+R+H + + ++ L E FE SDS R + ++ E Sbjct: 1018 HRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDEN 1077 Query: 506 TAFDAETDSEMNSQE-----------SRSDLEDMEEEEGTRSPTLEPPRGRSEAPDSLNG 554 F E ++SQ+ S+ + ED E ++ +P L+P D N Sbjct: 1078 ELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPV-SLLRKRDVKNS 1136 Query: 555 PLGPSEAS 562 PL P ++ Sbjct: 1137 PLEPDTST 1144 Score = 38.5 bits (88), Expect = 0.032 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 32/154 (20%) Query: 399 LQAELEEGE---------NPVPAFQ---SDGTDEPESKEPVEKEEEPDPEPPPVTPQVGE 446 +QAE EE E + VPA S + E E+KEP +EEE E P V+ + + Sbjct: 1229 MQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEE---EKPRVSEEQRQ 1285 Query: 447 GRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFESDSSHDSARASEGS-DSGSDKSLEGGG 505 + ++ P+ ++ D + + HD+ +G +S K LE Sbjct: 1286 SEEE---------QQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP 1336 Query: 506 TAFDA-------ETDSEMNSQESRSDLEDMEEEE 532 T D E+ + N Q+SR ++D EE E Sbjct: 1337 TREDVKEEPGVQESFLDANMQKSREKIKDKEETE 1370 >gi|168229156 NFKB activating protein [Homo sapiens] Length = 415 Score = 41.2 bits (95), Expect = 0.005 Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 16/149 (10%) Query: 420 EPESKE--PVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRR-----RHPPKVGDDS 472 EP+S E PVE EE T + + +KS + S RR+ R K +DS Sbjct: 154 EPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDS 213 Query: 473 DLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEE 532 D E+DSS + + +K + + + + + S S ++ +EE Sbjct: 214 DSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEE- 272 Query: 533 GTRSPTLEPP---RGRSEAPDSLNGPLGP 558 LE P R ++E P L GP P Sbjct: 273 -----FLENPWKDRTKAEEPSDLIGPEAP 296 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 40.4 bits (93), Expect = 0.009 Identities = 39/145 (26%), Positives = 56/145 (38%), Gaps = 26/145 (17%) Query: 399 LQAELEEGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSC 458 L +E EE + + D D+ E +E ++EE D GE +S S+ S Sbjct: 961 LDSEGEEASQESSS-EKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSL 1019 Query: 459 LRRRRHPPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNS 518 +SD +DS SE S S S S + + + S +S Sbjct: 1020 YA------------------DSDGENDSTSDSESSSSSSSSS------SSSSSSSSSSSS 1055 Query: 519 QESRSDLEDMEEEEGTRS-PTLEPP 542 S S ED EEEE + P+ PP Sbjct: 1056 SSSESSSEDEEEEERPAALPSASPP 1080 Score = 35.0 bits (79), Expect = 0.36 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 1/81 (1%) Query: 386 ALFSHLVNHVNIRLQAELEEGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVG 445 ALFS + V + + E E P P +E E + E EEE + + G Sbjct: 1326 ALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDG 1385 Query: 446 EGRKSRKFSRLSCLRRRRHPP 466 EG R+ R S RRRR PP Sbjct: 1386 EGALRRRSLR-SHARRRRPPP 1405 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 40.4 bits (93), Expect = 0.009 Identities = 30/140 (21%), Positives = 69/140 (49%), Gaps = 6/140 (4%) Query: 422 ESKEPVEKE-EEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFES 480 + K+ V+K+ E D E + + +K +K +L +++ K + +D G Sbjct: 321 DKKKDVKKDTESTDAESGDSKDERKDTKKDKK--KLKKDDKKKDTKKYPESTDTESGDAK 378 Query: 481 DSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLE 540 D+ +DS + S + DK + F +++SE+ S+ES+ D + ++++ +++ + Sbjct: 379 DARNDSRNLKKASKN-DDKKKDAKKITFSTDSESELESKESQKD--EKKDKKDSKTDNKK 435 Query: 541 PPRGRSEAPDSLNGPLGPSE 560 + E+ D+ + P G S+ Sbjct: 436 SVKNDEESTDADSEPKGDSK 455 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 39.7 bits (91), Expect = 0.015 Identities = 31/152 (20%), Positives = 62/152 (40%), Gaps = 1/152 (0%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRH 464 E +P + + E E++E E +P+ E T GE + + Sbjct: 751 ESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGED 810 Query: 465 PPKVGDDSDLSEGFESDS-SHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRS 523 ++ + +G E ++ S + + + G +K +E GG + +++ E +E + Sbjct: 811 EGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQE 870 Query: 524 DLEDMEEEEGTRSPTLEPPRGRSEAPDSLNGP 555 + E+ EE+E E +E P SL+ P Sbjct: 871 EEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWP 902 >gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo sapiens] Length = 1082 Score = 39.3 bits (90), Expect = 0.019 Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 11/144 (7%) Query: 430 EEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFESDSSHDSARA 489 EE PDP V +V E K + R+ + P D S ES S D Sbjct: 646 EEAPDPSVRNV--EVPEWTKCSNREK----RKEKEKPFYSDSEGESGPTESADS-DPESE 698 Query: 490 SEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLEPPRGRSEAP 549 SE S +S G ++ D + + ++ R + EE+G R + P + EA Sbjct: 699 SESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEAS 758 Query: 550 DSLNGPLGPSEASIASNLQAMSTQ 573 S G S++S +S+ M+++ Sbjct: 759 SSDEG----SDSSSSSSESEMTSE 778 Score = 36.6 bits (83), Expect = 0.12 Identities = 41/181 (22%), Positives = 63/181 (34%), Gaps = 15/181 (8%) Query: 383 FTLALFSHLVNHVNIRLQAELEEGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTP 442 F L SHL+N Q EL + P + PE + +E+ + E P + Sbjct: 622 FQLGSLSHLLNAKATGYQ-ELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSD 680 Query: 443 QVGEGRKSRKF-----SRLSCLRRRRHPPKVGDDSDLSEGFESDSSHDSARASEGSDSGS 497 GE + S + G+ S S+ + D + R SE S Sbjct: 681 SEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEE 740 Query: 498 D---------KSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLEPPRGRSEA 548 D +G ++ D +DS +S ES E EE+ S + + P A Sbjct: 741 DGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSA 800 Query: 549 P 549 P Sbjct: 801 P 801 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 39.3 bits (90), Expect = 0.019 Identities = 37/150 (24%), Positives = 59/150 (39%), Gaps = 11/150 (7%) Query: 402 ELEEG--ENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCL 459 E+EEG E + +G E E ++ E +EE + E + EG + ++ Sbjct: 726 EMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKE------- 778 Query: 460 RRRRHPPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQ 519 R K ++ D EG E ++ EG + + EG G + E + E + Sbjct: 779 ERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838 Query: 520 ESRSDLE--DMEEEEGTRSPTLEPPRGRSE 547 E + E + EEEEG E G E Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEEEGEEGEGE 868 Score = 38.5 bits (88), Expect = 0.032 Identities = 32/147 (21%), Positives = 53/147 (36%), Gaps = 30/147 (20%) Query: 404 EEGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRR 463 EEGE + +G +E E E+E E + E + GEG + Sbjct: 968 EEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEE----------- 1016 Query: 464 HPPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRS 523 ++ ++ E + EG + G ++ EG G +E+R Sbjct: 1017 ------EEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEG-------------EENRR 1057 Query: 524 DLEDMEEEEGTRSPTLEPPRGRSEAPD 550 + E+ EEEEG T E R + + Sbjct: 1058 NREEEEEEEGKYQETGEEENERQDGEE 1084 Score = 37.7 bits (86), Expect = 0.055 Identities = 42/165 (25%), Positives = 57/165 (34%), Gaps = 29/165 (17%) Query: 400 QAELEEGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCL 459 + E EEGE + G +E E E E+ EE + E + GEG Sbjct: 841 EGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEE---EEGEGE----------- 886 Query: 460 RRRRHPPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQ 519 G++ EG E + + EG G ++ EG G E + E + Sbjct: 887 ---------GEEEGEGEGEEEEGEGEGEEEGEGE--GEEEEGEGKGEEEGEEGEGEGEEE 935 Query: 520 ESRSDLED----MEEEEGTRSPTLEPPRGRSEAPDSLNGPLGPSE 560 E + ED EEEEG E G E G G E Sbjct: 936 EGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGE 980 Score = 33.1 bits (74), Expect = 1.4 Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 18/149 (12%) Query: 402 ELEEGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRR 461 E E+GE + + E E KE EKEE + GE ++ ++ + + Sbjct: 673 EREKGEKDKGRGEMERPGEGE-KELAEKEEWKKRD--------GEEQEQKEREQ-GHQKE 722 Query: 462 RRHPPKVGDDSDLSEG--FESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQ 519 R + G + + EG E D + + EG + G + +EG + E + + Sbjct: 723 RNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEG-----EREKEEGERKK 777 Query: 520 ESRSDLEDMEEEEGTRSP-TLEPPRGRSE 547 E R+ E+ EEEG + E GR E Sbjct: 778 EERAGKEEKGEEEGDQGEGEEEETEGRGE 806 Score = 31.2 bits (69), Expect = 5.2 Identities = 32/135 (23%), Positives = 49/135 (36%), Gaps = 23/135 (17%) Query: 400 QAELEEGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCL 459 + E EEGE DG E E +E + EE + E GEG + Sbjct: 931 EGEEEEGEGE----GEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGE---- 982 Query: 460 RRRRHPPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQ 519 ++ EG E + + EG + G + G + E + E+ + Sbjct: 983 ----------EEEGEGEGEEEEGEEEGEEEGEGEEEGEGE----GEEEEEGEVEGEVEGE 1028 Query: 520 ESRSDLEDME-EEEG 533 E + E+ E EEEG Sbjct: 1029 EGEGEGEEEEGEEEG 1043 >gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] Length = 1303 Score = 39.3 bits (90), Expect = 0.019 Identities = 31/132 (23%), Positives = 52/132 (39%), Gaps = 4/132 (3%) Query: 421 PESKEPVEKEEEPDPEPPPV-TPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFE 479 P + P E P P PPP TP + + L R P +D +L EG Sbjct: 5 PGTPPPPPSESPPPPSPPPPSTPSPPPCSPDARPATPHLLHHRLPLPDDREDGELEEGEL 64 Query: 480 SDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTL 539 D D A ++ + G ++S + G +++D E + + + + E+E RS Sbjct: 65 ED---DGAEETQDTSGGPERSRKEKGEKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKR 121 Query: 540 EPPRGRSEAPDS 551 + + A S Sbjct: 122 RKSKHKRHASSS 133 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 38.9 bits (89), Expect = 0.025 Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 9/132 (6%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRH 464 E V A ++ K P PP ++G+GRK K ++ Sbjct: 194 EARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME------E 247 Query: 465 PPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSD 524 + D D+S+ SS +S+ A GS S ++ E + E + S+E + Sbjct: 248 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE---EEEEEEGSTSEESEEEEEE 304 Query: 525 LEDMEEEEGTRS 536 E+ EEE G+ S Sbjct: 305 EEEEEEETGSNS 316 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 38.9 bits (89), Expect = 0.025 Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 9/132 (6%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRH 464 E V A ++ K P PP ++G+GRK K ++ Sbjct: 204 EARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME------E 257 Query: 465 PPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSD 524 + D D+S+ SS +S+ A GS S ++ E + E + S+E + Sbjct: 258 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE---EEEEEEGSTSEESEEEEEE 314 Query: 525 LEDMEEEEGTRS 536 E+ EEE G+ S Sbjct: 315 EEEEEEETGSNS 326 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 38.9 bits (89), Expect = 0.025 Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 9/132 (6%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRH 464 E V A ++ K P PP ++G+GRK K ++ Sbjct: 195 EARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME------E 248 Query: 465 PPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSD 524 + D D+S+ SS +S+ A GS S ++ E + E + S+E + Sbjct: 249 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE---EEEEEEGSTSEESEEEEEE 305 Query: 525 LEDMEEEEGTRS 536 E+ EEE G+ S Sbjct: 306 EEEEEEETGSNS 317 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 38.9 bits (89), Expect = 0.025 Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 9/132 (6%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRH 464 E V A ++ K P PP ++G+GRK K ++ Sbjct: 204 EARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME------E 257 Query: 465 PPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSD 524 + D D+S+ SS +S+ A GS S ++ E + E + S+E + Sbjct: 258 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE---EEEEEEGSTSEESEEEEEE 314 Query: 525 LEDMEEEEGTRS 536 E+ EEE G+ S Sbjct: 315 EEEEEEETGSNS 326 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 38.9 bits (89), Expect = 0.025 Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 9/132 (6%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRH 464 E V A ++ K P PP ++G+GRK K ++ Sbjct: 172 EARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME------E 225 Query: 465 PPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSD 524 + D D+S+ SS +S+ A GS S ++ E + E + S+E + Sbjct: 226 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE---EEEEEEGSTSEESEEEEEE 282 Query: 525 LEDMEEEEGTRS 536 E+ EEE G+ S Sbjct: 283 EEEEEEETGSNS 294 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 38.9 bits (89), Expect = 0.025 Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 9/132 (6%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRH 464 E V A ++ K P PP ++G+GRK K ++ Sbjct: 161 EARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME------E 214 Query: 465 PPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSD 524 + D D+S+ SS +S+ A GS S ++ E + E + S+E + Sbjct: 215 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE---EEEEEEGSTSEESEEEEEE 271 Query: 525 LEDMEEEEGTRS 536 E+ EEE G+ S Sbjct: 272 EEEEEEETGSNS 283 >gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2 [Homo sapiens] Length = 782 Score = 38.9 bits (89), Expect = 0.025 Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 9/132 (6%) Query: 405 EGENPVPAFQSDGTDEPESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRH 464 E V A ++ K P PP ++G+GRK K ++ Sbjct: 206 EARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME------E 259 Query: 465 PPKVGDDSDLSEGFESDSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSD 524 + D D+S+ SS +S+ A GS S ++ E + E + S+E + Sbjct: 260 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE---EEEEEEGSTSEESEEEEEE 316 Query: 525 LEDMEEEEGTRS 536 E+ EEE G+ S Sbjct: 317 EEEEEEETGSNS 328 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 41,658,072 Number of Sequences: 37866 Number of extensions: 2047585 Number of successful extensions: 12924 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 46 Number of HSP's successfully gapped in prelim test: 326 Number of HSP's that attempted gapping in prelim test: 11284 Number of HSP's gapped (non-prelim): 1561 length of query: 1016 length of database: 18,247,518 effective HSP length: 112 effective length of query: 904 effective length of database: 14,006,526 effective search space: 12661899504 effective search space used: 12661899504 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.