BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 [Homo sapiens] (557 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 1203 0.0 gi|5453557 ariadne homolog 2 [Homo sapiens] 329 4e-90 gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa... 196 5e-50 gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 149 5e-36 gi|35493801 ring finger protein 19 [Homo sapiens] 101 2e-21 gi|35493782 ring finger protein 19 [Homo sapiens] 101 2e-21 gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 99 1e-20 gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 98 2e-20 gi|38045938 ring finger protein 144 [Homo sapiens] 98 2e-20 gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 96 7e-20 gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 96 7e-20 gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 96 7e-20 gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 96 7e-20 gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 96 7e-20 gi|50284696 IBR domain containing 2 [Homo sapiens] 94 3e-19 gi|169790973 parkin isoform 3 [Homo sapiens] 84 3e-16 gi|169790971 parkin isoform 2 [Homo sapiens] 84 4e-16 gi|169790969 parkin isoform 1 [Homo sapiens] 84 4e-16 gi|22749145 ring finger protein 217 [Homo sapiens] 74 5e-13 gi|46370057 ring finger protein 216 isoform b [Homo sapiens] 62 1e-09 gi|46358403 ring finger protein 216 isoform a [Homo sapiens] 62 1e-09 gi|109150431 ring finger protein 31 [Homo sapiens] 62 1e-09 gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 56 8e-08 gi|119220564 one cut domain, family member 2 [Homo sapiens] 55 1e-07 gi|229577180 MPN domain containing isoform 2 [Homo sapiens] 55 2e-07 gi|31542699 MPN domain containing isoform 1 [Homo sapiens] 55 2e-07 gi|22748877 basic helix-loop-helix domain containing, class B, 5... 53 6e-07 gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 52 1e-06 gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 52 1e-06 gi|21322252 androgen receptor isoform 1 [Homo sapiens] 52 1e-06 >gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 [Homo sapiens] Length = 557 Score = 1203 bits (3113), Expect = 0.0 Identities = 557/557 (100%), Positives = 557/557 (100%) Query: 1 MDSDEGYNYEFDEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDG 60 MDSDEGYNYEFDEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDG Sbjct: 1 MDSDEGYNYEFDEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDG 60 Query: 61 LLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREV 120 LLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREV Sbjct: 61 LLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREV 120 Query: 121 NEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSS 180 NEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSS Sbjct: 121 NEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSS 180 Query: 181 AQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILV 240 AQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILV Sbjct: 181 AQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILV 240 Query: 241 DDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCG 300 DDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCG Sbjct: 241 DDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCG 300 Query: 301 RQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHM 360 RQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHM Sbjct: 301 RQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHM 360 Query: 361 VCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNR 420 VCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNR Sbjct: 361 VCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNR 420 Query: 421 YMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRATLMYTYVFAF 480 YMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRATLMYTYVFAF Sbjct: 421 YMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRATLMYTYVFAF 480 Query: 481 YLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLL 540 YLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLL Sbjct: 481 YLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLL 540 Query: 541 QHVHEGYEKDLWEYIED 557 QHVHEGYEKDLWEYIED Sbjct: 541 QHVHEGYEKDLWEYIED 557 >gi|5453557 ariadne homolog 2 [Homo sapiens] Length = 493 Score = 329 bits (844), Expect = 4e-90 Identities = 178/537 (33%), Positives = 294/537 (54%), Gaps = 58/537 (10%) Query: 12 DEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDGLLCGETGGGGG 71 D +EE + D EEEE+E++D+P G++E G+ E+ G Sbjct: 11 DSNEE--DYDPNCEEEEEEEEDDP-------GDIEDYYVGVASDVEQQG----------A 51 Query: 72 SALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATIT 131 A P E+Y++ LT ++ + E + + V++ ++ Sbjct: 52 DAFDP--------------------EEYQFTCLTYKESEGALNEHMTSLASVLKVSHSVA 91 Query: 132 RILLSHFNWDKEKLMERYFDGNLEKLFAECHVI-NPSKKSRTRQMNTRSSAQDMPCQICY 190 +++L +F+W ++++RY N +L E V NPSK T S C +C Sbjct: 92 KLILVNFHWQVSEILDRY-KSNSAQLLVEARVQPNPSKHVPT-------SHPPHHCAVCM 143 Query: 191 LNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLIT 250 L C H+FC CW ++ + ++++G+G +SC A C + ++ V L+ Sbjct: 144 QFVRKENLLSLACQHQFCRSCWEQHCSV-LVKDGVGVGVSCMAQDCPLRTPEDFVFPLLP 202 Query: 251 DSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRC-KCGRQFCFNCGE 309 + +++ KY+ + +VE + L+ CP DC V++VQ P A+ V+C +C FCF C + Sbjct: 203 NEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQ 262 Query: 310 NWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKA 369 +H P C ++KW+ KC DDSET+N+I+A+TK+CPKC++ IEK+GGCNHM C CK Sbjct: 263 MYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQC--SKCKH 320 Query: 370 EFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLR 429 +FCW+CLG W+ HGS +Y C+RY E+ + Q ++R AL++YLFY R+ NH +SL+ Sbjct: 321 DFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQ 380 Query: 430 FEHKLYAQVKQKMEEMQQHNM-SWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQS 488 E + Y ++ +K++E +N+ +WI+ Q+L+ A +L +CR TL YTY +A+Y++ + Sbjct: 381 LEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRK 440 Query: 489 IIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHE 545 +FE QA LE E LS +ER S D + ++++ E RRR LL+ H+ Sbjct: 441 KLFEYQQAQLEAEIENLSWKVERADSYD-----RGDLENQMHIAEQRRRTLLKDFHD 492 >gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sapiens] Length = 1089 Score = 196 bits (498), Expect = 5e-50 Identities = 145/518 (27%), Positives = 225/518 (43%), Gaps = 83/518 (16%) Query: 101 YEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAE 160 YE L + + + I E +++Q P LL +WD+EKL+E + N E Sbjct: 225 YEGLRPQDLRRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMS-NPENCCQR 283 Query: 161 CHVINPSKK-----------SRTRQMNTRSSAQDMP-------------CQICYLNYPNS 196 V P+ S TRSS C IC + S Sbjct: 284 SGVQMPTPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSI--S 341 Query: 197 YF---TGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSK 253 F + CGH FC CW +L KI +EG I CPA+ C LV + + +++ Sbjct: 342 VFEDPVDMPCGHDFCRGCWESFLNLKI-QEGEAHNIFCPAYDCFQLVPVDIIESVVSKEM 400 Query: 254 VKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKV-------------QYP--DAKPVRCK 298 K +Y +FVE N +KWCP P C V++ +P A V C Sbjct: 401 DK-RYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCG 459 Query: 299 CGRQFCFNCGENWHDPVKCKWLKKWIKKCDD--------------DSETSNWIAANTKEC 344 G FC+ C H+P C+ K W++K + D+ W+ N+K C Sbjct: 460 KGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPC 519 Query: 345 PKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSA---WYNCNRY------NED 395 C I+K+ GCNHM C CK +FCW+CL W+ H S+ +Y C RY E Sbjct: 520 ANCKSPIQKNEGCNHMQC--AKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQ 577 Query: 396 DAKAARDAQERSR--AALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEE----MQQHN 449 + +A+++ + L R++ Y R+ NH S + E +L K+KME+ +++ Sbjct: 578 SKEMTVEAEKKHKRFQELDRFMHYYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETE 637 Query: 450 MSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLK-KNNQSIIFENNQADLENATEVLSGY 508 + F++ AV VL + R L +Y + F+L+ K+ + IFE Q DLE TE L+ Sbjct: 638 GGCPDTTFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLA-- 695 Query: 509 LERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEG 546 + +++ L+ + K+ + +R+ L V G Sbjct: 696 --QKVNRPYLRTPRHKIIKAACLVQQKRQEFLASVARG 731 >gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo sapiens] Length = 2517 Score = 149 bits (377), Expect = 5e-36 Identities = 117/453 (25%), Positives = 190/453 (41%), Gaps = 43/453 (9%) Query: 104 LTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHV 163 ++ +++ M + +R+V E + + + LL+H +W E+L++ Y + L A Sbjct: 1997 MSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLC 2056 Query: 164 INPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEE 223 ++ ++ R + + C + L C H C CW+EYLTT+I E+ Sbjct: 2057 VHQAQAVPVRPDHCPVCVSPLGC--------DDDLPSLCCMHYCCKSCWNEYLTTRI-EQ 2107 Query: 224 GMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPD-CH 282 + +CP C + +++ +V KY+ + +VE L WC P C Sbjct: 2108 NLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCD 2167 Query: 283 HVVKVQYPDAKPVRCKCGRQFCFNCG-ENWHDPVKCKWLKKWIKKCDD---------DSE 332 ++ Q KCG CFNC H P C + +W+ DD +++ Sbjct: 2168 RILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWV---DDGGYYDGMSVEAQ 2224 Query: 333 TSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRY 392 + + +K CP C IEK+ GC HM C C FCW CL W+P+ +YNC+ Sbjct: 2225 SKHLAKLISKRCPSCQAPIEKNEGCLHMTCAK--CNHGFCWRCLKSWKPNHKDYYNCSAM 2282 Query: 393 NEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSW 452 +KAAR QE+ R+ Y R H Q+ F L +V E + + Sbjct: 2283 ---VSKAAR--QEK------RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFT- 2330 Query: 453 IEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERD 512 FL A L Q R L Y V++FY + + E +LE T L LE Sbjct: 2331 ----FLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEET 2386 Query: 513 ISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHE 545 + + +D+ ++ C S LL+ + E Sbjct: 2387 LLR--CRDLASSLRLLRADCLSTGMELLRRIQE 2417 Score = 30.0 bits (66), Expect = 5.8 Identities = 14/34 (41%), Positives = 21/34 (61%) Query: 13 EDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVE 46 E+EE +ED E ++DE D+E D+D+ E E Sbjct: 2463 EEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESE 2496 >gi|35493801 ring finger protein 19 [Homo sapiens] Length = 838 Score = 101 bits (251), Expect = 2e-21 Identities = 61/208 (29%), Positives = 93/208 (44%), Gaps = 23/208 (11%) Query: 186 CQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNT 244 C +C L + F + C H+ C+ C +YL +I E + ISCP C + + Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN--ISCPE--CTERFNPHD 187 Query: 245 VMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVV----KVQYPDAKPVRCKCG 300 + +++D + KY+ + ++ + +WCPAPDC + V P R CG Sbjct: 188 IRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCG 247 Query: 301 RQFCFNCGENWHDPVKCK----------WLKKWIKKCDDDSETSNWIAANTKECPKCHVT 350 +FC++C + WH C L+ S+ S A + K CP+C Sbjct: 248 TEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAY 307 Query: 351 IEK--DGGCNHMVCRNQNCKAEFCWVCL 376 I K DG CNHM C C EFCW+C+ Sbjct: 308 IIKMNDGSCNHMTC--AVCGCEFCWLCM 333 >gi|35493782 ring finger protein 19 [Homo sapiens] Length = 838 Score = 101 bits (251), Expect = 2e-21 Identities = 61/208 (29%), Positives = 93/208 (44%), Gaps = 23/208 (11%) Query: 186 CQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNT 244 C +C L + F + C H+ C+ C +YL +I E + ISCP C + + Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN--ISCPE--CTERFNPHD 187 Query: 245 VMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVV----KVQYPDAKPVRCKCG 300 + +++D + KY+ + ++ + +WCPAPDC + V P R CG Sbjct: 188 IRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCG 247 Query: 301 RQFCFNCGENWHDPVKCK----------WLKKWIKKCDDDSETSNWIAANTKECPKCHVT 350 +FC++C + WH C L+ S+ S A + K CP+C Sbjct: 248 TEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAY 307 Query: 351 IEK--DGGCNHMVCRNQNCKAEFCWVCL 376 I K DG CNHM C C EFCW+C+ Sbjct: 308 IIKMNDGSCNHMTC--AVCGCEFCWLCM 333 >gi|188219579 ring finger protein 19B isoform b [Homo sapiens] Length = 587 Score = 99.0 bits (245), Expect = 1e-20 Identities = 62/212 (29%), Positives = 95/212 (44%), Gaps = 23/212 (10%) Query: 181 AQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDIL 239 A+++ C +C + P L C H+ C C YL +I E + ISCP C Sbjct: 114 AEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV--PISCPE--CSER 169 Query: 240 VDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKC 299 ++ + + L+ D + KY+ + ++ + +WCPAPDC + V + Y A + C Sbjct: 170 LNPHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAV-IAYGCASCPKLTC 228 Query: 300 GR-----QFCFNCGENWHDPVKC--------KWLKKWIKKCDDDSETSNWIAANTKECPK 346 R +FC++C + WH C + L+ K S + K CP+ Sbjct: 229 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPR 288 Query: 347 CHVTIEK--DGGCNHMVCRNQNCKAEFCWVCL 376 C I K DG CNHM C C EFCW+C+ Sbjct: 289 CSAYIIKMNDGSCNHMTC--AVCGCEFCWLCM 318 Score = 33.5 bits (75), Expect = 0.53 Identities = 30/129 (23%), Positives = 50/129 (38%), Gaps = 30/129 (23%) Query: 271 RLLKWCPAPDCH----HVVKVQYPDAK-PVRCKCGRQFCFNCGE--NWHD--------PV 315 RLL CP C H ++++ +++ P+ C C E N HD P+ Sbjct: 133 RLLS-CPHRSCRDCLRHYLRLEISESRVPISCP-------ECSERLNPHDIRLLLADPPL 184 Query: 316 KCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDG--GCNHMVCRNQNCKAEFCW 373 K+ + +++ W A P C + G C + C + C+ EFC+ Sbjct: 185 MHKYEEFMLRRYLASDPDCRWCPA-----PDCGYAVIAYGCASCPKLTCEREGCQTEFCY 239 Query: 374 VCLGPWEPH 382 C W P+ Sbjct: 240 HCKQIWHPN 248 >gi|188219577 ring finger protein 19B isoform a [Homo sapiens] Length = 732 Score = 97.8 bits (242), Expect = 2e-20 Identities = 63/213 (29%), Positives = 97/213 (45%), Gaps = 24/213 (11%) Query: 181 AQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDIL 239 A+++ C +C + P L C H+ C C YL +I E + ISCP C Sbjct: 114 AEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV--PISCPE--CSER 169 Query: 240 VDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKC 299 ++ + + L+ D + KY+ + ++ + +WCPAPDC + V + Y A + C Sbjct: 170 LNPHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAV-IAYGCASCPKLTC 228 Query: 300 GR-----QFCFNCGENWHDPVKC--------KWLKKWIKKCDDDS-ETSNWIAANTKECP 345 R +FC++C + WH C + L+ K S + A + K CP Sbjct: 229 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCP 288 Query: 346 KCHVTIEK--DGGCNHMVCRNQNCKAEFCWVCL 376 +C I K DG CNHM C C EFCW+C+ Sbjct: 289 RCSAYIIKMNDGSCNHMTC--AVCGCEFCWLCM 319 Score = 33.5 bits (75), Expect = 0.53 Identities = 30/129 (23%), Positives = 50/129 (38%), Gaps = 30/129 (23%) Query: 271 RLLKWCPAPDCH----HVVKVQYPDAK-PVRCKCGRQFCFNCGE--NWHD--------PV 315 RLL CP C H ++++ +++ P+ C C E N HD P+ Sbjct: 133 RLLS-CPHRSCRDCLRHYLRLEISESRVPISCP-------ECSERLNPHDIRLLLADPPL 184 Query: 316 KCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDG--GCNHMVCRNQNCKAEFCW 373 K+ + +++ W A P C + G C + C + C+ EFC+ Sbjct: 185 MHKYEEFMLRRYLASDPDCRWCPA-----PDCGYAVIAYGCASCPKLTCEREGCQTEFCY 239 Query: 374 VCLGPWEPH 382 C W P+ Sbjct: 240 HCKQIWHPN 248 >gi|38045938 ring finger protein 144 [Homo sapiens] Length = 292 Score = 97.8 bits (242), Expect = 2e-20 Identities = 69/224 (30%), Positives = 101/224 (45%), Gaps = 31/224 (13%) Query: 172 TRQMNTRSSAQD--MPCQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQT 228 TR T A D + C++C YP T + +C FC C +Y+ +++EG+ Sbjct: 4 TRYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVEL-LIKEGLETA 62 Query: 229 ISCPAHGCDIL--VDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVK 286 ISCP C + +N + ++ +++ +Y+ L V + WCPA C V + Sbjct: 63 ISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQ 121 Query: 287 VQ---YPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWL----------KKWIKKCDDDSE 332 +Q +PV+CK C +FC C +WH C K +DD Sbjct: 122 LQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGETSAAFKMEEDD-- 179 Query: 333 TSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCL 376 A K CPKC V IE+D GC M+C+ NCK FCW CL Sbjct: 180 ------APIKRCPKCKVYIERDEGCAQMMCK--NCKHAFCWYCL 215 >gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 96.3 bits (238), Expect = 7e-20 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 36/222 (16%) Query: 186 CQICYLNYPNS---YFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDD 242 C IC+ S YF LEC H +C C +Y +I +G Q ++CP C + Sbjct: 220 CSICFCEKLGSECMYF--LECRHVYCKACLKDYFEIQI-RDGQVQCLNCPEPKCPSVATP 276 Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302 V L+ ++++ +Y L+ S ++ + +CP P C V + + C Sbjct: 277 GQVKELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFA 335 Query: 303 FCFNCGENWHDPVKCK---------------------------WLKKWIKKCDDDSETSN 335 FC C +H CK + K+ I+K ++ E+ Sbjct: 336 FCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395 Query: 336 WIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLG 377 W+ N+K CP C IEK GCN M C C FCW+C+G Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMG 435 >gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 96.3 bits (238), Expect = 7e-20 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 36/222 (16%) Query: 186 CQICYLNYPNS---YFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDD 242 C IC+ S YF LEC H +C C +Y +I +G Q ++CP C + Sbjct: 220 CSICFCEKLGSECMYF--LECRHVYCKACLKDYFEIQI-RDGQVQCLNCPEPKCPSVATP 276 Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302 V L+ ++++ +Y L+ S ++ + +CP P C V + + C Sbjct: 277 GQVKELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFA 335 Query: 303 FCFNCGENWHDPVKCK---------------------------WLKKWIKKCDDDSETSN 335 FC C +H CK + K+ I+K ++ E+ Sbjct: 336 FCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395 Query: 336 WIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLG 377 W+ N+K CP C IEK GCN M C C FCW+C+G Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMG 435 >gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 96.3 bits (238), Expect = 7e-20 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 36/222 (16%) Query: 186 CQICYLNYPNS---YFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDD 242 C IC+ S YF LEC H +C C +Y +I +G Q ++CP C + Sbjct: 220 CSICFCEKLGSECMYF--LECRHVYCKACLKDYFEIQI-RDGQVQCLNCPEPKCPSVATP 276 Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302 V L+ ++++ +Y L+ S ++ + +CP P C V + + C Sbjct: 277 GQVKELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFA 335 Query: 303 FCFNCGENWHDPVKCK---------------------------WLKKWIKKCDDDSETSN 335 FC C +H CK + K+ I+K ++ E+ Sbjct: 336 FCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395 Query: 336 WIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLG 377 W+ N+K CP C IEK GCN M C C FCW+C+G Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMG 435 >gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] Length = 348 Score = 96.3 bits (238), Expect = 7e-20 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 36/222 (16%) Query: 186 CQICYLNYPNS---YFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDD 242 C IC+ S YF LEC H +C C +Y +I +G Q ++CP C + Sbjct: 94 CSICFCEKLGSECMYF--LECRHVYCKACLKDYFEIQI-RDGQVQCLNCPEPKCPSVATP 150 Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302 V L+ ++++ +Y L+ S ++ + +CP P C V + + C Sbjct: 151 GQVKELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFA 209 Query: 303 FCFNCGENWHDPVKCK---------------------------WLKKWIKKCDDDSETSN 335 FC C +H CK + K+ I+K ++ E+ Sbjct: 210 FCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 269 Query: 336 WIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLG 377 W+ N+K CP C IEK GCN M C C FCW+C+G Sbjct: 270 WLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMG 309 >gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 96.3 bits (238), Expect = 7e-20 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 36/222 (16%) Query: 186 CQICYLNYPNS---YFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDD 242 C IC+ S YF LEC H +C C +Y +I +G Q ++CP C + Sbjct: 220 CSICFCEKLGSECMYF--LECRHVYCKACLKDYFEIQI-RDGQVQCLNCPEPKCPSVATP 276 Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302 V L+ ++++ +Y L+ S ++ + +CP P C V + + C Sbjct: 277 GQVKELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFA 335 Query: 303 FCFNCGENWHDPVKCK---------------------------WLKKWIKKCDDDSETSN 335 FC C +H CK + K+ I+K ++ E+ Sbjct: 336 FCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395 Query: 336 WIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLG 377 W+ N+K CP C IEK GCN M C C FCW+C+G Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMG 435 >gi|50284696 IBR domain containing 2 [Homo sapiens] Length = 303 Score = 94.0 bits (232), Expect = 3e-19 Identities = 62/198 (31%), Positives = 88/198 (44%), Gaps = 11/198 (5%) Query: 186 CQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGC--DILVDD 242 C++C T L EC FC C +Y+ I EG G I+CP C + + Sbjct: 30 CKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAI-REGCGSPITCPDMVCLNHGTLQE 88 Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD-AKPVRCKCGR 301 + L+ + +L YQ L V + WCP DC V V D +PV +C Sbjct: 89 AEIACLVPVDQFQL-YQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPS 147 Query: 302 ---QFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCN 358 +FC C + WH V C+ + + + + A K+CP C V IE++ GC Sbjct: 148 CHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVCRVYIERNEGCA 207 Query: 359 HMVCRNQNCKAEFCWVCL 376 M+C+ NCK FCW CL Sbjct: 208 QMMCK--NCKHTFCWYCL 223 >gi|169790973 parkin isoform 3 [Homo sapiens] Length = 316 Score = 84.3 bits (207), Expect = 3e-16 Identities = 65/270 (24%), Positives = 120/270 (44%), Gaps = 39/270 (14%) Query: 151 DGNLEKLFAECHVINPSKKSRTRQMNT-RSSAQDMPCQICY-LNYPNSYFTGLECG--HK 206 D +++ F +C S K + ++ ++++++ C C + P F +C H Sbjct: 53 DWTVQEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVF---QCNSRHV 109 Query: 207 FCMQCWSEYLTTKIMEEG------MGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQH 260 C+ C+ Y T++ + +G ++ C A + L+ + R++ + + Q+ Sbjct: 110 ICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQY 169 Query: 261 LITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCK------CGRQFCFNCGENWHDP 314 ++ +L CP P C + + PD + V C+ CG FC C E +H+ Sbjct: 170 GAEECVLQMGGVL--CPRPGCGAGLLPE-PDQRKVTCEGGNGLGCGFAFCRECKEAYHEG 226 Query: 315 VKCKWL-------KKWIKKCDDDSETSNWIAAN-------TKECPKCHVTIEKDGGCNHM 360 +C + + + + +E + W AA+ TK CP+CHV +EK+GGC HM Sbjct: 227 -ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHM 285 Query: 361 VCRNQNCKAEFCWVCLGPWEP--HGSAWYN 388 C C+ E+CW C W G W++ Sbjct: 286 KCPQPQCRLEWCWNCGCEWNRVCMGDHWFD 315 >gi|169790971 parkin isoform 2 [Homo sapiens] Length = 437 Score = 83.6 bits (205), Expect = 4e-16 Identities = 55/212 (25%), Positives = 95/212 (44%), Gaps = 32/212 (15%) Query: 205 HKFCMQCWSEYLTTKIMEEG------MGQTISCPAHGCDILVDDNTVMRLITDSKVKLKY 258 H C+ C+ Y T++ + +G ++ C A + L+ + R++ + + Sbjct: 229 HVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQ 288 Query: 259 QHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCK------CGRQFCFNCGENWH 312 Q+ ++ +L CP P C + + PD + V C+ CG FC C E +H Sbjct: 289 QYGAEECVLQMGGVL--CPRPGCGAGLLPE-PDQRKVTCEGGNGLGCGFAFCRECKEAYH 345 Query: 313 DPVKCKWL-------KKWIKKCDDDSETSNWIAAN-------TKECPKCHVTIEKDGGCN 358 + +C + + + + +E + W AA+ TK CP+CHV +EK+GGC Sbjct: 346 EG-ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCM 404 Query: 359 HMVCRNQNCKAEFCWVCLGPWEP--HGSAWYN 388 HM C C+ E+CW C W G W++ Sbjct: 405 HMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFD 436 >gi|169790969 parkin isoform 1 [Homo sapiens] Length = 465 Score = 83.6 bits (205), Expect = 4e-16 Identities = 55/212 (25%), Positives = 95/212 (44%), Gaps = 32/212 (15%) Query: 205 HKFCMQCWSEYLTTKIMEEG------MGQTISCPAHGCDILVDDNTVMRLITDSKVKLKY 258 H C+ C+ Y T++ + +G ++ C A + L+ + R++ + + Sbjct: 257 HVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQ 316 Query: 259 QHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCK------CGRQFCFNCGENWH 312 Q+ ++ +L CP P C + + PD + V C+ CG FC C E +H Sbjct: 317 QYGAEECVLQMGGVL--CPRPGCGAGLLPE-PDQRKVTCEGGNGLGCGFAFCRECKEAYH 373 Query: 313 DPVKCKWL-------KKWIKKCDDDSETSNWIAAN-------TKECPKCHVTIEKDGGCN 358 + +C + + + + +E + W AA+ TK CP+CHV +EK+GGC Sbjct: 374 EG-ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCM 432 Query: 359 HMVCRNQNCKAEFCWVCLGPWEP--HGSAWYN 388 HM C C+ E+CW C W G W++ Sbjct: 433 HMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFD 464 >gi|22749145 ring finger protein 217 [Homo sapiens] Length = 275 Score = 73.6 bits (179), Expect = 5e-13 Identities = 49/169 (28%), Positives = 73/169 (43%), Gaps = 23/169 (13%) Query: 221 MEEGMGQT-ISCPAHGCDILVDDNTVMRLIT-DSKVKLKYQHLITNSFVECNRL-LKWCP 277 M+ +GQ I CP C +++ TV+ +T + +K KY F+E R+ P Sbjct: 1 MKVQLGQVEIKCPITECFEFLEETTVVYNLTHEDSIKYKY-------FLELGRIDSSTKP 53 Query: 278 APDCHHVVKVQYPDAKP----------VRCK-CGRQFCFNCGENWHDPVKCKWLKKWIKK 326 P C H + P ++C C +CF C WH+ V CK KK K Sbjct: 54 CPQCKHFTTFKKKGHIPTPSRSESKYKIQCPTCQFVWCFKCHSPWHEGVNCKEYKKGDKL 113 Query: 327 CDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVC 375 + N ++CPKC + I++ GC+HM C C FC+ C Sbjct: 114 LRHWASEIEHGQRNAQKCPKCKIHIQRTEGCDHMTC--SQCNTNFCYRC 160 >gi|46370057 ring finger protein 216 isoform b [Homo sapiens] Length = 866 Score = 62.4 bits (150), Expect = 1e-09 Identities = 64/268 (23%), Positives = 100/268 (37%), Gaps = 38/268 (14%) Query: 174 QMNTRSSAQD---MPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTIS 230 QMN +D + C+ CY +P T H FC +C Y + G + +S Sbjct: 500 QMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLE-LS 558 Query: 231 CPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYP 290 C C + + +++ + + KY V + P C + Sbjct: 559 CMEGSCTCSFPTSELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD-S 616 Query: 291 DAKPVRCK---CGRQFCFNCGENW--HDPVKCKWLKKWIKKCDDDSETS---NWIAANTK 342 D K C C ++ C C W H+ + C+ L + K D TS AA + Sbjct: 617 DVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAE---KDDIKYRTSIEEKMTAARIR 673 Query: 343 ECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWV-----------CLGPWEPHGSAWYNCNR 391 +C KC + K GCN M CR C A+ C++ C P P G+ C+R Sbjct: 674 KCHKCGTGLIKSEGCNRMSCR---CGAQMCYLCRVSINGYDHFCQHPRSP-GAPCQECSR 729 Query: 392 YN------EDDAKAARDAQERSRAALQR 413 + EDD K + Q+ + +R Sbjct: 730 CSLWTDPTEDDEKLIEEIQKEAEEEQKR 757 Score = 40.0 bits (92), Expect = 0.006 Identities = 25/90 (27%), Positives = 32/90 (35%), Gaps = 3/90 (3%) Query: 330 DSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNC 389 + E + A CP C D C N +C+ E C C G W+ H C Sbjct: 591 EEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNG--LTC 648 Query: 390 NRYNE-DDAKAARDAQERSRAALQRYLFYC 418 E DD K +E+ AA R C Sbjct: 649 EELAEKDDIKYRTSIEEKMTAARIRKCHKC 678 >gi|46358403 ring finger protein 216 isoform a [Homo sapiens] Length = 923 Score = 62.4 bits (150), Expect = 1e-09 Identities = 64/268 (23%), Positives = 100/268 (37%), Gaps = 38/268 (14%) Query: 174 QMNTRSSAQD---MPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTIS 230 QMN +D + C+ CY +P T H FC +C Y + G + +S Sbjct: 557 QMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLE-LS 615 Query: 231 CPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYP 290 C C + + +++ + + KY V + P C + Sbjct: 616 CMEGSCTCSFPTSELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD-S 673 Query: 291 DAKPVRCK---CGRQFCFNCGENW--HDPVKCKWLKKWIKKCDDDSETS---NWIAANTK 342 D K C C ++ C C W H+ + C+ L + K D TS AA + Sbjct: 674 DVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAE---KDDIKYRTSIEEKMTAARIR 730 Query: 343 ECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWV-----------CLGPWEPHGSAWYNCNR 391 +C KC + K GCN M CR C A+ C++ C P P G+ C+R Sbjct: 731 KCHKCGTGLIKSEGCNRMSCR---CGAQMCYLCRVSINGYDHFCQHPRSP-GAPCQECSR 786 Query: 392 YN------EDDAKAARDAQERSRAALQR 413 + EDD K + Q+ + +R Sbjct: 787 CSLWTDPTEDDEKLIEEIQKEAEEEQKR 814 Score = 40.0 bits (92), Expect = 0.006 Identities = 25/90 (27%), Positives = 32/90 (35%), Gaps = 3/90 (3%) Query: 330 DSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNC 389 + E + A CP C D C N +C+ E C C G W+ H C Sbjct: 648 EEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNG--LTC 705 Query: 390 NRYNE-DDAKAARDAQERSRAALQRYLFYC 418 E DD K +E+ AA R C Sbjct: 706 EELAEKDDIKYRTSIEEKMTAARIRKCHKC 735 >gi|109150431 ring finger protein 31 [Homo sapiens] Length = 1072 Score = 62.0 bits (149), Expect = 1e-09 Identities = 54/257 (21%), Positives = 99/257 (38%), Gaps = 32/257 (12%) Query: 163 VINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIM 221 V+ + S+ R R AQ+ C +C P++ L C C C+ ++ T + Sbjct: 678 VVEAVRHSQDRAFLRRLLAQE--CAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALK 735 Query: 222 EEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLK----------YQHLITNSFVECNR 271 E+ + + CPA G L DD ++ + ++L+ + +T + + Sbjct: 736 EKHITDMV-CPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDP 794 Query: 272 LLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCFNCGENW---HDPVKCKWLKKWIKKCD 328 WC C + + +C + FC C W H C+ + W + D Sbjct: 795 KFLWCA--QCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMND 852 Query: 329 DDSETSN---WIAANTKECPKCHVTIE-KDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGS 384 + + ++ N +CPKC + GGC H C C+ +FC C + Sbjct: 853 PEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHC--TQCRHQFCSGCY-------N 903 Query: 385 AWYNCNRYNEDDAKAAR 401 A+Y N+ E + + + Sbjct: 904 AFYAKNKCPEPNCRVKK 920 >gi|110347449 POU domain, class 4, transcription factor 1 [Homo sapiens] Length = 419 Score = 56.2 bits (134), Expect = 8e-08 Identities = 28/41 (68%), Positives = 28/41 (68%), Gaps = 1/41 (2%) Query: 53 GVGGERDGLLCGE-TGGGGGSALGPGGGGGGGGGGGGGGPG 92 G GG DG G GGGGG GPGGGGGGG GGGGGGPG Sbjct: 139 GGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPG 179 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/41 (60%), Positives = 26/41 (63%), Gaps = 7/41 (17%) Query: 53 GVGGERDGLLCGETGGGGGSALGPGGGGG-GGGGGGGGGPG 92 G GG G GGGG+ GPGGGGG GGGGG GGGPG Sbjct: 130 GAGG------AGAAAGGGGAHDGPGGGGGPGGGGGPGGGPG 164 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/44 (56%), Positives = 25/44 (56%), Gaps = 2/44 (4%) Query: 50 PGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGGGGPGH 93 PG G G G G GGGGG GPGGGGGG GGG GG H Sbjct: 147 PGGGGGPGGGGGPGGGPGGGGGG--GPGGGGGGPGGGLLGGSAH 188 >gi|119220564 one cut domain, family member 2 [Homo sapiens] Length = 504 Score = 55.5 bits (132), Expect = 1e-07 Identities = 26/37 (70%), Positives = 26/37 (70%), Gaps = 6/37 (16%) Query: 60 GLLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQE 96 G L G GGG G GGGGGGGGGGGGGPGHEQE Sbjct: 30 GTLHGPAGGGSG------GGGGGGGGGGGGGPGHEQE 60 >gi|229577180 MPN domain containing isoform 2 [Homo sapiens] Length = 451 Score = 55.1 bits (131), Expect = 2e-07 Identities = 31/78 (39%), Positives = 38/78 (48%), Gaps = 15/78 (19%) Query: 15 EECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSAL 74 E S EE +ED+DE + + + P G GG R G GGGS++ Sbjct: 5 EPLSPAGGAGEEAPEEDEDEAEAEDPE-------RPNAGAGGGRSG--------GGGSSV 49 Query: 75 GPGGGGGGGGGGGGGGPG 92 GGGGGG G GG GGPG Sbjct: 50 SGGGGGGGAGAGGCGGPG 67 >gi|31542699 MPN domain containing isoform 1 [Homo sapiens] Length = 471 Score = 55.1 bits (131), Expect = 2e-07 Identities = 31/78 (39%), Positives = 38/78 (48%), Gaps = 15/78 (19%) Query: 15 EECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSAL 74 E S EE +ED+DE + + + P G GG R G GGGS++ Sbjct: 5 EPLSPAGGAGEEAPEEDEDEAEAEDPE-------RPNAGAGGGRSG--------GGGSSV 49 Query: 75 GPGGGGGGGGGGGGGGPG 92 GGGGGG G GG GGPG Sbjct: 50 SGGGGGGGAGAGGCGGPG 67 >gi|22748877 basic helix-loop-helix domain containing, class B, 5 [Homo sapiens] Length = 381 Score = 53.1 bits (126), Expect = 6e-07 Identities = 32/81 (39%), Positives = 40/81 (49%), Gaps = 8/81 (9%) Query: 20 EDSGAEEEEDEDDDEPDDDTLDLGEVE-LVEPGLGVGGERDGLLCGETGGGGGSALGPGG 78 E SG E+ D+D D + L G + PG G GG + C GG+++ PGG Sbjct: 140 ESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGG 199 Query: 79 GGGGGGG-------GGGGGPG 92 GGGGGG GGGGG G Sbjct: 200 LGGGGGGGSSSGSSGGGGGSG 220 Score = 39.7 bits (91), Expect = 0.007 Identities = 19/32 (59%), Positives = 20/32 (62%) Query: 57 ERDGLLCGETGGGGGSALGPGGGGGGGGGGGG 88 E GLL GGGGG + G GGGGGGG G G Sbjct: 71 EGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPG 102 Score = 36.6 bits (83), Expect = 0.062 Identities = 18/28 (64%), Positives = 18/28 (64%), Gaps = 4/28 (14%) Query: 69 GGGSALGPGGGGGGG----GGGGGGGPG 92 G G L P GGGGGG GGGGGGG G Sbjct: 72 GAGLLLPPPGGGGGGSAGSGGGGGGGVG 99 >gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 isoform 1 [Homo sapiens] Length = 468 Score = 52.4 bits (124), Expect = 1e-06 Identities = 55/232 (23%), Positives = 91/232 (39%), Gaps = 35/232 (15%) Query: 174 QMNTRS---SAQDMPCQICY-LNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTI 229 Q++ RS + + C +CY + P EC H FC +C + E + Sbjct: 225 QLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAE-----V 279 Query: 230 SCP----AHGCDILVDDNTVMRLITDSKVKLKYQHLITN--SFVECNRLLKW-CPAPDCH 282 SCP + C + + + L+T YQ + S E + C PDC Sbjct: 280 SCPFIDNTYSCSGKLLEREIKALLTPED----YQRFLDLGISIAENRSAFSYHCKTPDCK 335 Query: 283 HVVKVQYPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIK-KCDDD---SETSNWI 337 + D C C C C + H+ + CK ++ + + +D +T+ + Sbjct: 336 GWCFFE-DDVNEFTCPVCFHVNCLLC-KAIHEQMNCKEYQEDLALRAQNDVAARQTTEML 393 Query: 338 AANTKE-----CPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGP-WEPHG 383 ++ CP+C + ++K GC+ + C C E CWV GP W P G Sbjct: 394 KVMLQQGEAMRCPQCQIVVQKKDGCDWIRC--TVCHTEICWVTKGPRWGPGG 443 >gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 isoform 2 [Homo sapiens] Length = 510 Score = 52.4 bits (124), Expect = 1e-06 Identities = 55/232 (23%), Positives = 91/232 (39%), Gaps = 35/232 (15%) Query: 174 QMNTRS---SAQDMPCQICY-LNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTI 229 Q++ RS + + C +CY + P EC H FC +C + E + Sbjct: 267 QLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAE-----V 321 Query: 230 SCP----AHGCDILVDDNTVMRLITDSKVKLKYQHLITN--SFVECNRLLKW-CPAPDCH 282 SCP + C + + + L+T YQ + S E + C PDC Sbjct: 322 SCPFIDNTYSCSGKLLEREIKALLTPED----YQRFLDLGISIAENRSAFSYHCKTPDCK 377 Query: 283 HVVKVQYPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIK-KCDDD---SETSNWI 337 + D C C C C + H+ + CK ++ + + +D +T+ + Sbjct: 378 GWCFFE-DDVNEFTCPVCFHVNCLLC-KAIHEQMNCKEYQEDLALRAQNDVAARQTTEML 435 Query: 338 AANTKE-----CPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGP-WEPHG 383 ++ CP+C + ++K GC+ + C C E CWV GP W P G Sbjct: 436 KVMLQQGEAMRCPQCQIVVQKKDGCDWIRC--TVCHTEICWVTKGPRWGPGG 485 >gi|21322252 androgen receptor isoform 1 [Homo sapiens] Length = 920 Score = 52.0 bits (123), Expect = 1e-06 Identities = 23/34 (67%), Positives = 24/34 (70%) Query: 59 DGLLCGETGGGGGSALGPGGGGGGGGGGGGGGPG 92 +G L G GGGGG G GGGGGGGGGGGGG G Sbjct: 443 EGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAG 476 Score = 40.0 bits (92), Expect = 0.006 Identities = 19/33 (57%), Positives = 20/33 (60%) Query: 56 GERDGLLCGETGGGGGSALGPGGGGGGGGGGGG 88 G+ G G GGGGG G GGGGGGGGG G Sbjct: 444 GQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAG 476 Score = 38.5 bits (88), Expect = 0.016 Identities = 17/28 (60%), Positives = 17/28 (60%) Query: 64 GETGGGGGSALGPGGGGGGGGGGGGGGP 91 G GGGGG G GGGGGGGG G P Sbjct: 453 GGGGGGGGGGGGGGGGGGGGGEAGAVAP 480 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.136 0.441 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,128,540 Number of Sequences: 37866 Number of extensions: 1379229 Number of successful extensions: 38314 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 759 Number of HSP's successfully gapped in prelim test: 263 Number of HSP's that attempted gapping in prelim test: 16753 Number of HSP's gapped (non-prelim): 10353 length of query: 557 length of database: 18,247,518 effective HSP length: 107 effective length of query: 450 effective length of database: 14,195,856 effective search space: 6388135200 effective search space used: 6388135200 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.