Guide to the Human Genome
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Search of human proteins with 187761373

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
         (557 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro...  1203   0.0  
gi|5453557 ariadne homolog 2 [Homo sapiens]                           329   4e-90
gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa...   196   5e-50
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo...   149   5e-36
gi|35493801 ring finger protein 19 [Homo sapiens]                     101   2e-21
gi|35493782 ring finger protein 19 [Homo sapiens]                     101   2e-21
gi|188219579 ring finger protein 19B isoform b [Homo sapiens]          99   1e-20
gi|188219577 ring finger protein 19B isoform a [Homo sapiens]          98   2e-20
gi|38045938 ring finger protein 144 [Homo sapiens]                     98   2e-20
gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]            96   7e-20
gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]            96   7e-20
gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]            96   7e-20
gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]            96   7e-20
gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]             96   7e-20
gi|50284696 IBR domain containing 2 [Homo sapiens]                     94   3e-19
gi|169790973 parkin isoform 3 [Homo sapiens]                           84   3e-16
gi|169790971 parkin isoform 2 [Homo sapiens]                           84   4e-16
gi|169790969 parkin isoform 1 [Homo sapiens]                           84   4e-16
gi|22749145 ring finger protein 217 [Homo sapiens]                     74   5e-13
gi|46370057 ring finger protein 216 isoform b [Homo sapiens]           62   1e-09
gi|46358403 ring finger protein 216 isoform a [Homo sapiens]           62   1e-09
gi|109150431 ring finger protein 31 [Homo sapiens]                     62   1e-09
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    56   8e-08
gi|119220564 one cut domain, family member 2 [Homo sapiens]            55   1e-07
gi|229577180 MPN domain containing isoform 2 [Homo sapiens]            55   2e-07
gi|31542699 MPN domain containing isoform 1 [Homo sapiens]             55   2e-07
gi|22748877 basic helix-loop-helix domain containing, class B, 5...    53   6e-07
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is...    52   1e-06
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ...    52   1e-06
gi|21322252 androgen receptor isoform 1 [Homo sapiens]                 52   1e-06

>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
           protein homolog 1 [Homo sapiens]
          Length = 557

 Score = 1203 bits (3113), Expect = 0.0
 Identities = 557/557 (100%), Positives = 557/557 (100%)

Query: 1   MDSDEGYNYEFDEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDG 60
           MDSDEGYNYEFDEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDG
Sbjct: 1   MDSDEGYNYEFDEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDG 60

Query: 61  LLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREV 120
           LLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREV
Sbjct: 61  LLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREV 120

Query: 121 NEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSS 180
           NEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSS
Sbjct: 121 NEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSS 180

Query: 181 AQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILV 240
           AQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILV
Sbjct: 181 AQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILV 240

Query: 241 DDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCG 300
           DDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCG
Sbjct: 241 DDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCG 300

Query: 301 RQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHM 360
           RQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHM
Sbjct: 301 RQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHM 360

Query: 361 VCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNR 420
           VCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNR
Sbjct: 361 VCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNR 420

Query: 421 YMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRATLMYTYVFAF 480
           YMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRATLMYTYVFAF
Sbjct: 421 YMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRATLMYTYVFAF 480

Query: 481 YLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLL 540
           YLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLL
Sbjct: 481 YLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLL 540

Query: 541 QHVHEGYEKDLWEYIED 557
           QHVHEGYEKDLWEYIED
Sbjct: 541 QHVHEGYEKDLWEYIED 557


>gi|5453557 ariadne homolog 2 [Homo sapiens]
          Length = 493

 Score =  329 bits (844), Expect = 4e-90
 Identities = 178/537 (33%), Positives = 294/537 (54%), Gaps = 58/537 (10%)

Query: 12  DEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDGLLCGETGGGGG 71
           D +EE  + D   EEEE+E++D+P       G++E    G+    E+ G           
Sbjct: 11  DSNEE--DYDPNCEEEEEEEEDDP-------GDIEDYYVGVASDVEQQG----------A 51

Query: 72  SALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATIT 131
            A  P                    E+Y++  LT ++    + E +  +  V++   ++ 
Sbjct: 52  DAFDP--------------------EEYQFTCLTYKESEGALNEHMTSLASVLKVSHSVA 91

Query: 132 RILLSHFNWDKEKLMERYFDGNLEKLFAECHVI-NPSKKSRTRQMNTRSSAQDMPCQICY 190
           +++L +F+W   ++++RY   N  +L  E  V  NPSK   T       S     C +C 
Sbjct: 92  KLILVNFHWQVSEILDRY-KSNSAQLLVEARVQPNPSKHVPT-------SHPPHHCAVCM 143

Query: 191 LNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLIT 250
                     L C H+FC  CW ++ +  ++++G+G  +SC A  C +   ++ V  L+ 
Sbjct: 144 QFVRKENLLSLACQHQFCRSCWEQHCSV-LVKDGVGVGVSCMAQDCPLRTPEDFVFPLLP 202

Query: 251 DSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRC-KCGRQFCFNCGE 309
           + +++ KY+  +   +VE +  L+ CP  DC  V++VQ P A+ V+C +C   FCF C +
Sbjct: 203 NEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQ 262

Query: 310 NWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKA 369
            +H P  C  ++KW+ KC DDSET+N+I+A+TK+CPKC++ IEK+GGCNHM C    CK 
Sbjct: 263 MYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQC--SKCKH 320

Query: 370 EFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLR 429
           +FCW+CLG W+ HGS +Y C+RY E+     +  Q ++R AL++YLFY  R+ NH +SL+
Sbjct: 321 DFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQ 380

Query: 430 FEHKLYAQVKQKMEEMQQHNM-SWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQS 488
            E + Y ++ +K++E   +N+ +WI+ Q+L+ A  +L +CR TL YTY +A+Y++   + 
Sbjct: 381 LEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRK 440

Query: 489 IIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHE 545
            +FE  QA LE   E LS  +ER  S D     +  ++++    E RRR LL+  H+
Sbjct: 441 KLFEYQQAQLEAEIENLSWKVERADSYD-----RGDLENQMHIAEQRRRTLLKDFHD 492


>gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo
           sapiens]
          Length = 1089

 Score =  196 bits (498), Expect = 5e-50
 Identities = 145/518 (27%), Positives = 225/518 (43%), Gaps = 83/518 (16%)

Query: 101 YEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAE 160
           YE L  + + +     I E  +++Q P      LL   +WD+EKL+E +   N E     
Sbjct: 225 YEGLRPQDLRRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMS-NPENCCQR 283

Query: 161 CHVINPSKK-----------SRTRQMNTRSSAQDMP-------------CQICYLNYPNS 196
             V  P+             S      TRSS                  C IC  +   S
Sbjct: 284 SGVQMPTPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSI--S 341

Query: 197 YF---TGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSK 253
            F     + CGH FC  CW  +L  KI +EG    I CPA+ C  LV  + +  +++   
Sbjct: 342 VFEDPVDMPCGHDFCRGCWESFLNLKI-QEGEAHNIFCPAYDCFQLVPVDIIESVVSKEM 400

Query: 254 VKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKV-------------QYP--DAKPVRCK 298
            K +Y      +FVE N  +KWCP P C   V++              +P   A  V C 
Sbjct: 401 DK-RYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCG 459

Query: 299 CGRQFCFNCGENWHDPVKCKWLKKWIKKCDD--------------DSETSNWIAANTKEC 344
            G  FC+ C    H+P  C+  K W++K  +              D+    W+  N+K C
Sbjct: 460 KGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPC 519

Query: 345 PKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSA---WYNCNRY------NED 395
             C   I+K+ GCNHM C    CK +FCW+CL  W+ H S+   +Y C RY       E 
Sbjct: 520 ANCKSPIQKNEGCNHMQC--AKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQ 577

Query: 396 DAKAARDAQERSR--AALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEE----MQQHN 449
             +   +A+++ +    L R++ Y  R+ NH  S + E +L    K+KME+    +++  
Sbjct: 578 SKEMTVEAEKKHKRFQELDRFMHYYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETE 637

Query: 450 MSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLK-KNNQSIIFENNQADLENATEVLSGY 508
               +  F++ AV VL + R  L  +Y + F+L+ K+ +  IFE  Q DLE  TE L+  
Sbjct: 638 GGCPDTTFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLA-- 695

Query: 509 LERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEG 546
             + +++  L+  + K+       + +R+  L  V  G
Sbjct: 696 --QKVNRPYLRTPRHKIIKAACLVQQKRQEFLASVARG 731


>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
            sapiens]
          Length = 2517

 Score =  149 bits (377), Expect = 5e-36
 Identities = 117/453 (25%), Positives = 190/453 (41%), Gaps = 43/453 (9%)

Query: 104  LTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHV 163
            ++ +++   M + +R+V E +     + + LL+H +W  E+L++ Y +     L A    
Sbjct: 1997 MSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLC 2056

Query: 164  INPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEE 223
            ++ ++    R  +       + C        +     L C H  C  CW+EYLTT+I E+
Sbjct: 2057 VHQAQAVPVRPDHCPVCVSPLGC--------DDDLPSLCCMHYCCKSCWNEYLTTRI-EQ 2107

Query: 224  GMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPD-CH 282
             +    +CP   C        +  +++  +V  KY+  +   +VE    L WC  P  C 
Sbjct: 2108 NLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCD 2167

Query: 283  HVVKVQYPDAKPVRCKCGRQFCFNCG-ENWHDPVKCKWLKKWIKKCDD---------DSE 332
             ++  Q         KCG   CFNC     H P  C  + +W+   DD         +++
Sbjct: 2168 RILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWV---DDGGYYDGMSVEAQ 2224

Query: 333  TSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRY 392
            + +     +K CP C   IEK+ GC HM C    C   FCW CL  W+P+   +YNC+  
Sbjct: 2225 SKHLAKLISKRCPSCQAPIEKNEGCLHMTCAK--CNHGFCWRCLKSWKPNHKDYYNCSAM 2282

Query: 393  NEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSW 452
                +KAAR  QE+      R+  Y  R   H Q+  F   L  +V    E     + + 
Sbjct: 2283 ---VSKAAR--QEK------RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFT- 2330

Query: 453  IEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERD 512
                FL  A   L Q R  L Y  V++FY +      + E    +LE  T  L   LE  
Sbjct: 2331 ----FLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEET 2386

Query: 513  ISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHE 545
            + +   +D+   ++     C S    LL+ + E
Sbjct: 2387 LLR--CRDLASSLRLLRADCLSTGMELLRRIQE 2417



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 14/34 (41%), Positives = 21/34 (61%)

Query: 13   EDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVE 46
            E+EE  +ED   E ++DE D+E D+D+    E E
Sbjct: 2463 EEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESE 2496


>gi|35493801 ring finger protein 19 [Homo sapiens]
          Length = 838

 Score =  101 bits (251), Expect = 2e-21
 Identities = 61/208 (29%), Positives = 93/208 (44%), Gaps = 23/208 (11%)

Query: 186 CQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNT 244
           C +C L +    F  +  C H+ C+ C  +YL  +I E  +   ISCP   C    + + 
Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN--ISCPE--CTERFNPHD 187

Query: 245 VMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVV----KVQYPDAKPVRCKCG 300
           +  +++D  +  KY+  +   ++  +   +WCPAPDC + V        P     R  CG
Sbjct: 188 IRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCG 247

Query: 301 RQFCFNCGENWHDPVKCK----------WLKKWIKKCDDDSETSNWIAANTKECPKCHVT 350
            +FC++C + WH    C            L+         S+ S   A + K CP+C   
Sbjct: 248 TEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAY 307

Query: 351 IEK--DGGCNHMVCRNQNCKAEFCWVCL 376
           I K  DG CNHM C    C  EFCW+C+
Sbjct: 308 IIKMNDGSCNHMTC--AVCGCEFCWLCM 333


>gi|35493782 ring finger protein 19 [Homo sapiens]
          Length = 838

 Score =  101 bits (251), Expect = 2e-21
 Identities = 61/208 (29%), Positives = 93/208 (44%), Gaps = 23/208 (11%)

Query: 186 CQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNT 244
           C +C L +    F  +  C H+ C+ C  +YL  +I E  +   ISCP   C    + + 
Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN--ISCPE--CTERFNPHD 187

Query: 245 VMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVV----KVQYPDAKPVRCKCG 300
           +  +++D  +  KY+  +   ++  +   +WCPAPDC + V        P     R  CG
Sbjct: 188 IRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCG 247

Query: 301 RQFCFNCGENWHDPVKCK----------WLKKWIKKCDDDSETSNWIAANTKECPKCHVT 350
            +FC++C + WH    C            L+         S+ S   A + K CP+C   
Sbjct: 248 TEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAY 307

Query: 351 IEK--DGGCNHMVCRNQNCKAEFCWVCL 376
           I K  DG CNHM C    C  EFCW+C+
Sbjct: 308 IIKMNDGSCNHMTC--AVCGCEFCWLCM 333


>gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
          Length = 587

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 62/212 (29%), Positives = 95/212 (44%), Gaps = 23/212 (10%)

Query: 181 AQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDIL 239
           A+++ C +C +  P      L  C H+ C  C   YL  +I E  +   ISCP   C   
Sbjct: 114 AEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV--PISCPE--CSER 169

Query: 240 VDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKC 299
           ++ + +  L+ D  +  KY+  +   ++  +   +WCPAPDC + V + Y  A   +  C
Sbjct: 170 LNPHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAV-IAYGCASCPKLTC 228

Query: 300 GR-----QFCFNCGENWHDPVKC--------KWLKKWIKKCDDDSETSNWIAANTKECPK 346
            R     +FC++C + WH    C        + L+   K     S        + K CP+
Sbjct: 229 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPR 288

Query: 347 CHVTIEK--DGGCNHMVCRNQNCKAEFCWVCL 376
           C   I K  DG CNHM C    C  EFCW+C+
Sbjct: 289 CSAYIIKMNDGSCNHMTC--AVCGCEFCWLCM 318



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 30/129 (23%), Positives = 50/129 (38%), Gaps = 30/129 (23%)

Query: 271 RLLKWCPAPDCH----HVVKVQYPDAK-PVRCKCGRQFCFNCGE--NWHD--------PV 315
           RLL  CP   C     H ++++  +++ P+ C         C E  N HD        P+
Sbjct: 133 RLLS-CPHRSCRDCLRHYLRLEISESRVPISCP-------ECSERLNPHDIRLLLADPPL 184

Query: 316 KCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDG--GCNHMVCRNQNCKAEFCW 373
             K+ +  +++         W  A     P C   +   G   C  + C  + C+ EFC+
Sbjct: 185 MHKYEEFMLRRYLASDPDCRWCPA-----PDCGYAVIAYGCASCPKLTCEREGCQTEFCY 239

Query: 374 VCLGPWEPH 382
            C   W P+
Sbjct: 240 HCKQIWHPN 248


>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
          Length = 732

 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 63/213 (29%), Positives = 97/213 (45%), Gaps = 24/213 (11%)

Query: 181 AQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDIL 239
           A+++ C +C +  P      L  C H+ C  C   YL  +I E  +   ISCP   C   
Sbjct: 114 AEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV--PISCPE--CSER 169

Query: 240 VDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKC 299
           ++ + +  L+ D  +  KY+  +   ++  +   +WCPAPDC + V + Y  A   +  C
Sbjct: 170 LNPHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAV-IAYGCASCPKLTC 228

Query: 300 GR-----QFCFNCGENWHDPVKC--------KWLKKWIKKCDDDS-ETSNWIAANTKECP 345
            R     +FC++C + WH    C        + L+   K     S    +  A + K CP
Sbjct: 229 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCP 288

Query: 346 KCHVTIEK--DGGCNHMVCRNQNCKAEFCWVCL 376
           +C   I K  DG CNHM C    C  EFCW+C+
Sbjct: 289 RCSAYIIKMNDGSCNHMTC--AVCGCEFCWLCM 319



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 30/129 (23%), Positives = 50/129 (38%), Gaps = 30/129 (23%)

Query: 271 RLLKWCPAPDCH----HVVKVQYPDAK-PVRCKCGRQFCFNCGE--NWHD--------PV 315
           RLL  CP   C     H ++++  +++ P+ C         C E  N HD        P+
Sbjct: 133 RLLS-CPHRSCRDCLRHYLRLEISESRVPISCP-------ECSERLNPHDIRLLLADPPL 184

Query: 316 KCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDG--GCNHMVCRNQNCKAEFCW 373
             K+ +  +++         W  A     P C   +   G   C  + C  + C+ EFC+
Sbjct: 185 MHKYEEFMLRRYLASDPDCRWCPA-----PDCGYAVIAYGCASCPKLTCEREGCQTEFCY 239

Query: 374 VCLGPWEPH 382
            C   W P+
Sbjct: 240 HCKQIWHPN 248


>gi|38045938 ring finger protein 144 [Homo sapiens]
          Length = 292

 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 69/224 (30%), Positives = 101/224 (45%), Gaps = 31/224 (13%)

Query: 172 TRQMNTRSSAQD--MPCQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQT 228
           TR   T   A D  + C++C   YP    T + +C   FC  C  +Y+   +++EG+   
Sbjct: 4   TRYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVEL-LIKEGLETA 62

Query: 229 ISCPAHGCDIL--VDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVK 286
           ISCP   C     + +N +  ++  +++  +Y+ L     V  +    WCPA  C  V +
Sbjct: 63  ISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQ 121

Query: 287 VQ---YPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWL----------KKWIKKCDDDSE 332
           +Q       +PV+CK C  +FC  C  +WH    C                 K  +DD  
Sbjct: 122 LQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGETSAAFKMEEDD-- 179

Query: 333 TSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCL 376
                 A  K CPKC V IE+D GC  M+C+  NCK  FCW CL
Sbjct: 180 ------APIKRCPKCKVYIERDEGCAQMMCK--NCKHAFCWYCL 215


>gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 36/222 (16%)

Query: 186 CQICYLNYPNS---YFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDD 242
           C IC+     S   YF  LEC H +C  C  +Y   +I  +G  Q ++CP   C  +   
Sbjct: 220 CSICFCEKLGSECMYF--LECRHVYCKACLKDYFEIQI-RDGQVQCLNCPEPKCPSVATP 276

Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302
             V  L+ ++++  +Y  L+  S ++    + +CP P C   V  +      +   C   
Sbjct: 277 GQVKELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFA 335

Query: 303 FCFNCGENWHDPVKCK---------------------------WLKKWIKKCDDDSETSN 335
           FC  C   +H    CK                           + K+ I+K  ++ E+  
Sbjct: 336 FCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395

Query: 336 WIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLG 377
           W+  N+K CP C   IEK  GCN M C    C   FCW+C+G
Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMG 435


>gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 36/222 (16%)

Query: 186 CQICYLNYPNS---YFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDD 242
           C IC+     S   YF  LEC H +C  C  +Y   +I  +G  Q ++CP   C  +   
Sbjct: 220 CSICFCEKLGSECMYF--LECRHVYCKACLKDYFEIQI-RDGQVQCLNCPEPKCPSVATP 276

Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302
             V  L+ ++++  +Y  L+  S ++    + +CP P C   V  +      +   C   
Sbjct: 277 GQVKELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFA 335

Query: 303 FCFNCGENWHDPVKCK---------------------------WLKKWIKKCDDDSETSN 335
           FC  C   +H    CK                           + K+ I+K  ++ E+  
Sbjct: 336 FCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395

Query: 336 WIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLG 377
           W+  N+K CP C   IEK  GCN M C    C   FCW+C+G
Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMG 435


>gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 36/222 (16%)

Query: 186 CQICYLNYPNS---YFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDD 242
           C IC+     S   YF  LEC H +C  C  +Y   +I  +G  Q ++CP   C  +   
Sbjct: 220 CSICFCEKLGSECMYF--LECRHVYCKACLKDYFEIQI-RDGQVQCLNCPEPKCPSVATP 276

Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302
             V  L+ ++++  +Y  L+  S ++    + +CP P C   V  +      +   C   
Sbjct: 277 GQVKELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFA 335

Query: 303 FCFNCGENWHDPVKCK---------------------------WLKKWIKKCDDDSETSN 335
           FC  C   +H    CK                           + K+ I+K  ++ E+  
Sbjct: 336 FCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395

Query: 336 WIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLG 377
           W+  N+K CP C   IEK  GCN M C    C   FCW+C+G
Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMG 435


>gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
          Length = 348

 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 36/222 (16%)

Query: 186 CQICYLNYPNS---YFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDD 242
           C IC+     S   YF  LEC H +C  C  +Y   +I  +G  Q ++CP   C  +   
Sbjct: 94  CSICFCEKLGSECMYF--LECRHVYCKACLKDYFEIQI-RDGQVQCLNCPEPKCPSVATP 150

Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302
             V  L+ ++++  +Y  L+  S ++    + +CP P C   V  +      +   C   
Sbjct: 151 GQVKELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFA 209

Query: 303 FCFNCGENWHDPVKCK---------------------------WLKKWIKKCDDDSETSN 335
           FC  C   +H    CK                           + K+ I+K  ++ E+  
Sbjct: 210 FCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 269

Query: 336 WIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLG 377
           W+  N+K CP C   IEK  GCN M C    C   FCW+C+G
Sbjct: 270 WLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMG 309


>gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 36/222 (16%)

Query: 186 CQICYLNYPNS---YFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDD 242
           C IC+     S   YF  LEC H +C  C  +Y   +I  +G  Q ++CP   C  +   
Sbjct: 220 CSICFCEKLGSECMYF--LECRHVYCKACLKDYFEIQI-RDGQVQCLNCPEPKCPSVATP 276

Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302
             V  L+ ++++  +Y  L+  S ++    + +CP P C   V  +      +   C   
Sbjct: 277 GQVKELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFA 335

Query: 303 FCFNCGENWHDPVKCK---------------------------WLKKWIKKCDDDSETSN 335
           FC  C   +H    CK                           + K+ I+K  ++ E+  
Sbjct: 336 FCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395

Query: 336 WIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLG 377
           W+  N+K CP C   IEK  GCN M C    C   FCW+C+G
Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMG 435


>gi|50284696 IBR domain containing 2 [Homo sapiens]
          Length = 303

 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 62/198 (31%), Positives = 88/198 (44%), Gaps = 11/198 (5%)

Query: 186 CQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGC--DILVDD 242
           C++C         T L EC   FC  C  +Y+   I  EG G  I+CP   C     + +
Sbjct: 30  CKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAI-REGCGSPITCPDMVCLNHGTLQE 88

Query: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD-AKPVRCKCGR 301
             +  L+   + +L YQ L     V  +    WCP  DC  V  V   D  +PV  +C  
Sbjct: 89  AEIACLVPVDQFQL-YQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPS 147

Query: 302 ---QFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCN 358
              +FC  C + WH  V C+  +  +   +  +       A  K+CP C V IE++ GC 
Sbjct: 148 CHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVCRVYIERNEGCA 207

Query: 359 HMVCRNQNCKAEFCWVCL 376
            M+C+  NCK  FCW CL
Sbjct: 208 QMMCK--NCKHTFCWYCL 223


>gi|169790973 parkin isoform 3 [Homo sapiens]
          Length = 316

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 65/270 (24%), Positives = 120/270 (44%), Gaps = 39/270 (14%)

Query: 151 DGNLEKLFAECHVINPSKKSRTRQMNT-RSSAQDMPCQICY-LNYPNSYFTGLECG--HK 206
           D  +++ F +C     S K  +  ++   ++++++ C  C  +  P   F   +C   H 
Sbjct: 53  DWTVQEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVF---QCNSRHV 109

Query: 207 FCMQCWSEYLTTKIMEEG------MGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQH 260
            C+ C+  Y  T++ +        +G ++ C A   + L+ +    R++ + +     Q+
Sbjct: 110 ICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQY 169

Query: 261 LITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCK------CGRQFCFNCGENWHDP 314
                 ++   +L  CP P C   +  + PD + V C+      CG  FC  C E +H+ 
Sbjct: 170 GAEECVLQMGGVL--CPRPGCGAGLLPE-PDQRKVTCEGGNGLGCGFAFCRECKEAYHEG 226

Query: 315 VKCKWL-------KKWIKKCDDDSETSNWIAAN-------TKECPKCHVTIEKDGGCNHM 360
            +C  +        +  +  +  +E + W AA+       TK CP+CHV +EK+GGC HM
Sbjct: 227 -ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHM 285

Query: 361 VCRNQNCKAEFCWVCLGPWEP--HGSAWYN 388
            C    C+ E+CW C   W     G  W++
Sbjct: 286 KCPQPQCRLEWCWNCGCEWNRVCMGDHWFD 315


>gi|169790971 parkin isoform 2 [Homo sapiens]
          Length = 437

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 55/212 (25%), Positives = 95/212 (44%), Gaps = 32/212 (15%)

Query: 205 HKFCMQCWSEYLTTKIMEEG------MGQTISCPAHGCDILVDDNTVMRLITDSKVKLKY 258
           H  C+ C+  Y  T++ +        +G ++ C A   + L+ +    R++ + +     
Sbjct: 229 HVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQ 288

Query: 259 QHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCK------CGRQFCFNCGENWH 312
           Q+      ++   +L  CP P C   +  + PD + V C+      CG  FC  C E +H
Sbjct: 289 QYGAEECVLQMGGVL--CPRPGCGAGLLPE-PDQRKVTCEGGNGLGCGFAFCRECKEAYH 345

Query: 313 DPVKCKWL-------KKWIKKCDDDSETSNWIAAN-------TKECPKCHVTIEKDGGCN 358
           +  +C  +        +  +  +  +E + W AA+       TK CP+CHV +EK+GGC 
Sbjct: 346 EG-ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCM 404

Query: 359 HMVCRNQNCKAEFCWVCLGPWEP--HGSAWYN 388
           HM C    C+ E+CW C   W     G  W++
Sbjct: 405 HMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFD 436


>gi|169790969 parkin isoform 1 [Homo sapiens]
          Length = 465

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 55/212 (25%), Positives = 95/212 (44%), Gaps = 32/212 (15%)

Query: 205 HKFCMQCWSEYLTTKIMEEG------MGQTISCPAHGCDILVDDNTVMRLITDSKVKLKY 258
           H  C+ C+  Y  T++ +        +G ++ C A   + L+ +    R++ + +     
Sbjct: 257 HVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQ 316

Query: 259 QHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCK------CGRQFCFNCGENWH 312
           Q+      ++   +L  CP P C   +  + PD + V C+      CG  FC  C E +H
Sbjct: 317 QYGAEECVLQMGGVL--CPRPGCGAGLLPE-PDQRKVTCEGGNGLGCGFAFCRECKEAYH 373

Query: 313 DPVKCKWL-------KKWIKKCDDDSETSNWIAAN-------TKECPKCHVTIEKDGGCN 358
           +  +C  +        +  +  +  +E + W AA+       TK CP+CHV +EK+GGC 
Sbjct: 374 EG-ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCM 432

Query: 359 HMVCRNQNCKAEFCWVCLGPWEP--HGSAWYN 388
           HM C    C+ E+CW C   W     G  W++
Sbjct: 433 HMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFD 464


>gi|22749145 ring finger protein 217 [Homo sapiens]
          Length = 275

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 49/169 (28%), Positives = 73/169 (43%), Gaps = 23/169 (13%)

Query: 221 MEEGMGQT-ISCPAHGCDILVDDNTVMRLIT-DSKVKLKYQHLITNSFVECNRL-LKWCP 277
           M+  +GQ  I CP   C   +++ TV+  +T +  +K KY       F+E  R+     P
Sbjct: 1   MKVQLGQVEIKCPITECFEFLEETTVVYNLTHEDSIKYKY-------FLELGRIDSSTKP 53

Query: 278 APDCHHVVKVQYPDAKP----------VRCK-CGRQFCFNCGENWHDPVKCKWLKKWIKK 326
            P C H    +     P          ++C  C   +CF C   WH+ V CK  KK  K 
Sbjct: 54  CPQCKHFTTFKKKGHIPTPSRSESKYKIQCPTCQFVWCFKCHSPWHEGVNCKEYKKGDKL 113

Query: 327 CDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVC 375
               +        N ++CPKC + I++  GC+HM C    C   FC+ C
Sbjct: 114 LRHWASEIEHGQRNAQKCPKCKIHIQRTEGCDHMTC--SQCNTNFCYRC 160


>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
          Length = 866

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 64/268 (23%), Positives = 100/268 (37%), Gaps = 38/268 (14%)

Query: 174 QMNTRSSAQD---MPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTIS 230
           QMN     +D   + C+ CY  +P    T     H FC +C   Y    +   G  + +S
Sbjct: 500 QMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLE-LS 558

Query: 231 CPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYP 290
           C    C      + + +++  + +  KY        V      +    P C     +   
Sbjct: 559 CMEGSCTCSFPTSELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD-S 616

Query: 291 DAKPVRCK---CGRQFCFNCGENW--HDPVKCKWLKKWIKKCDDDSETS---NWIAANTK 342
           D K   C    C ++ C  C   W  H+ + C+ L +   K D    TS      AA  +
Sbjct: 617 DVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAE---KDDIKYRTSIEEKMTAARIR 673

Query: 343 ECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWV-----------CLGPWEPHGSAWYNCNR 391
           +C KC   + K  GCN M CR   C A+ C++           C  P  P G+    C+R
Sbjct: 674 KCHKCGTGLIKSEGCNRMSCR---CGAQMCYLCRVSINGYDHFCQHPRSP-GAPCQECSR 729

Query: 392 YN------EDDAKAARDAQERSRAALQR 413
            +      EDD K   + Q+ +    +R
Sbjct: 730 CSLWTDPTEDDEKLIEEIQKEAEEEQKR 757



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 25/90 (27%), Positives = 32/90 (35%), Gaps = 3/90 (3%)

Query: 330 DSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNC 389
           + E +   A     CP C      D       C N +C+ E C  C G W+ H      C
Sbjct: 591 EEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNG--LTC 648

Query: 390 NRYNE-DDAKAARDAQERSRAALQRYLFYC 418
               E DD K     +E+  AA  R    C
Sbjct: 649 EELAEKDDIKYRTSIEEKMTAARIRKCHKC 678


>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
          Length = 923

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 64/268 (23%), Positives = 100/268 (37%), Gaps = 38/268 (14%)

Query: 174 QMNTRSSAQD---MPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTIS 230
           QMN     +D   + C+ CY  +P    T     H FC +C   Y    +   G  + +S
Sbjct: 557 QMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLE-LS 615

Query: 231 CPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYP 290
           C    C      + + +++  + +  KY        V      +    P C     +   
Sbjct: 616 CMEGSCTCSFPTSELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD-S 673

Query: 291 DAKPVRCK---CGRQFCFNCGENW--HDPVKCKWLKKWIKKCDDDSETS---NWIAANTK 342
           D K   C    C ++ C  C   W  H+ + C+ L +   K D    TS      AA  +
Sbjct: 674 DVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAE---KDDIKYRTSIEEKMTAARIR 730

Query: 343 ECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWV-----------CLGPWEPHGSAWYNCNR 391
           +C KC   + K  GCN M CR   C A+ C++           C  P  P G+    C+R
Sbjct: 731 KCHKCGTGLIKSEGCNRMSCR---CGAQMCYLCRVSINGYDHFCQHPRSP-GAPCQECSR 786

Query: 392 YN------EDDAKAARDAQERSRAALQR 413
            +      EDD K   + Q+ +    +R
Sbjct: 787 CSLWTDPTEDDEKLIEEIQKEAEEEQKR 814



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 25/90 (27%), Positives = 32/90 (35%), Gaps = 3/90 (3%)

Query: 330 DSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNC 389
           + E +   A     CP C      D       C N +C+ E C  C G W+ H      C
Sbjct: 648 EEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNG--LTC 705

Query: 390 NRYNE-DDAKAARDAQERSRAALQRYLFYC 418
               E DD K     +E+  AA  R    C
Sbjct: 706 EELAEKDDIKYRTSIEEKMTAARIRKCHKC 735


>gi|109150431 ring finger protein 31 [Homo sapiens]
          Length = 1072

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 54/257 (21%), Positives = 99/257 (38%), Gaps = 32/257 (12%)

Query: 163 VINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIM 221
           V+   + S+ R    R  AQ+  C +C    P++    L  C    C  C+ ++ T  + 
Sbjct: 678 VVEAVRHSQDRAFLRRLLAQE--CAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALK 735

Query: 222 EEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLK----------YQHLITNSFVECNR 271
           E+ +   + CPA G   L DD  ++   +   ++L+          +   +T   +  + 
Sbjct: 736 EKHITDMV-CPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDP 794

Query: 272 LLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCFNCGENW---HDPVKCKWLKKWIKKCD 328
              WC    C      +    +    +C + FC  C   W   H    C+  + W +  D
Sbjct: 795 KFLWCA--QCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMND 852

Query: 329 DDSETSN---WIAANTKECPKCHVTIE-KDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGS 384
            + +      ++  N  +CPKC  +     GGC H  C    C+ +FC  C        +
Sbjct: 853 PEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHC--TQCRHQFCSGCY-------N 903

Query: 385 AWYNCNRYNEDDAKAAR 401
           A+Y  N+  E + +  +
Sbjct: 904 AFYAKNKCPEPNCRVKK 920


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 28/41 (68%), Positives = 28/41 (68%), Gaps = 1/41 (2%)

Query: 53  GVGGERDGLLCGE-TGGGGGSALGPGGGGGGGGGGGGGGPG 92
           G GG  DG   G   GGGGG   GPGGGGGGG GGGGGGPG
Sbjct: 139 GGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPG 179



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 25/41 (60%), Positives = 26/41 (63%), Gaps = 7/41 (17%)

Query: 53  GVGGERDGLLCGETGGGGGSALGPGGGGG-GGGGGGGGGPG 92
           G GG       G   GGGG+  GPGGGGG GGGGG GGGPG
Sbjct: 130 GAGG------AGAAAGGGGAHDGPGGGGGPGGGGGPGGGPG 164



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 25/44 (56%), Positives = 25/44 (56%), Gaps = 2/44 (4%)

Query: 50  PGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGGGGPGH 93
           PG G G    G   G  GGGGG   GPGGGGGG GGG  GG  H
Sbjct: 147 PGGGGGPGGGGGPGGGPGGGGGG--GPGGGGGGPGGGLLGGSAH 188


>gi|119220564 one cut domain, family member 2 [Homo sapiens]
          Length = 504

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 26/37 (70%), Positives = 26/37 (70%), Gaps = 6/37 (16%)

Query: 60 GLLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQE 96
          G L G  GGG G      GGGGGGGGGGGGGPGHEQE
Sbjct: 30 GTLHGPAGGGSG------GGGGGGGGGGGGGPGHEQE 60


>gi|229577180 MPN domain containing isoform 2 [Homo sapiens]
          Length = 451

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 31/78 (39%), Positives = 38/78 (48%), Gaps = 15/78 (19%)

Query: 15 EECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSAL 74
          E  S      EE  +ED+DE + +  +        P  G GG R G        GGGS++
Sbjct: 5  EPLSPAGGAGEEAPEEDEDEAEAEDPE-------RPNAGAGGGRSG--------GGGSSV 49

Query: 75 GPGGGGGGGGGGGGGGPG 92
            GGGGGG G GG GGPG
Sbjct: 50 SGGGGGGGAGAGGCGGPG 67


>gi|31542699 MPN domain containing isoform 1 [Homo sapiens]
          Length = 471

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 31/78 (39%), Positives = 38/78 (48%), Gaps = 15/78 (19%)

Query: 15 EECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSAL 74
          E  S      EE  +ED+DE + +  +        P  G GG R G        GGGS++
Sbjct: 5  EPLSPAGGAGEEAPEEDEDEAEAEDPE-------RPNAGAGGGRSG--------GGGSSV 49

Query: 75 GPGGGGGGGGGGGGGGPG 92
            GGGGGG G GG GGPG
Sbjct: 50 SGGGGGGGAGAGGCGGPG 67


>gi|22748877 basic helix-loop-helix domain containing, class B, 5
           [Homo sapiens]
          Length = 381

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 32/81 (39%), Positives = 40/81 (49%), Gaps = 8/81 (9%)

Query: 20  EDSGAEEEEDEDDDEPDDDTLDLGEVE-LVEPGLGVGGERDGLLCGETGGGGGSALGPGG 78
           E SG E+  D+D D   +  L  G  +    PG G GG +    C      GG+++ PGG
Sbjct: 140 ESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGG 199

Query: 79  GGGGGGG-------GGGGGPG 92
            GGGGGG       GGGGG G
Sbjct: 200 LGGGGGGGSSSGSSGGGGGSG 220



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 19/32 (59%), Positives = 20/32 (62%)

Query: 57  ERDGLLCGETGGGGGSALGPGGGGGGGGGGGG 88
           E  GLL    GGGGG + G GGGGGGG G  G
Sbjct: 71  EGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPG 102



 Score = 36.6 bits (83), Expect = 0.062
 Identities = 18/28 (64%), Positives = 18/28 (64%), Gaps = 4/28 (14%)

Query: 69 GGGSALGPGGGGGGG----GGGGGGGPG 92
          G G  L P GGGGGG    GGGGGGG G
Sbjct: 72 GAGLLLPPPGGGGGGSAGSGGGGGGGVG 99


>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1
           isoform 1 [Homo sapiens]
          Length = 468

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 55/232 (23%), Positives = 91/232 (39%), Gaps = 35/232 (15%)

Query: 174 QMNTRS---SAQDMPCQICY-LNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTI 229
           Q++ RS   + +   C +CY +  P       EC H FC +C    +      E     +
Sbjct: 225 QLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAE-----V 279

Query: 230 SCP----AHGCDILVDDNTVMRLITDSKVKLKYQHLITN--SFVECNRLLKW-CPAPDCH 282
           SCP     + C   + +  +  L+T       YQ  +    S  E      + C  PDC 
Sbjct: 280 SCPFIDNTYSCSGKLLEREIKALLTPED----YQRFLDLGISIAENRSAFSYHCKTPDCK 335

Query: 283 HVVKVQYPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIK-KCDDD---SETSNWI 337
                +  D     C  C    C  C +  H+ + CK  ++ +  +  +D    +T+  +
Sbjct: 336 GWCFFE-DDVNEFTCPVCFHVNCLLC-KAIHEQMNCKEYQEDLALRAQNDVAARQTTEML 393

Query: 338 AANTKE-----CPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGP-WEPHG 383
               ++     CP+C + ++K  GC+ + C    C  E CWV  GP W P G
Sbjct: 394 KVMLQQGEAMRCPQCQIVVQKKDGCDWIRC--TVCHTEICWVTKGPRWGPGG 443


>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
           isoform 2 [Homo sapiens]
          Length = 510

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 55/232 (23%), Positives = 91/232 (39%), Gaps = 35/232 (15%)

Query: 174 QMNTRS---SAQDMPCQICY-LNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTI 229
           Q++ RS   + +   C +CY +  P       EC H FC +C    +      E     +
Sbjct: 267 QLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAE-----V 321

Query: 230 SCP----AHGCDILVDDNTVMRLITDSKVKLKYQHLITN--SFVECNRLLKW-CPAPDCH 282
           SCP     + C   + +  +  L+T       YQ  +    S  E      + C  PDC 
Sbjct: 322 SCPFIDNTYSCSGKLLEREIKALLTPED----YQRFLDLGISIAENRSAFSYHCKTPDCK 377

Query: 283 HVVKVQYPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIK-KCDDD---SETSNWI 337
                +  D     C  C    C  C +  H+ + CK  ++ +  +  +D    +T+  +
Sbjct: 378 GWCFFE-DDVNEFTCPVCFHVNCLLC-KAIHEQMNCKEYQEDLALRAQNDVAARQTTEML 435

Query: 338 AANTKE-----CPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGP-WEPHG 383
               ++     CP+C + ++K  GC+ + C    C  E CWV  GP W P G
Sbjct: 436 KVMLQQGEAMRCPQCQIVVQKKDGCDWIRC--TVCHTEICWVTKGPRWGPGG 485


>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
          Length = 920

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 23/34 (67%), Positives = 24/34 (70%)

Query: 59  DGLLCGETGGGGGSALGPGGGGGGGGGGGGGGPG 92
           +G L G  GGGGG   G GGGGGGGGGGGGG  G
Sbjct: 443 EGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAG 476



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 19/33 (57%), Positives = 20/33 (60%)

Query: 56  GERDGLLCGETGGGGGSALGPGGGGGGGGGGGG 88
           G+  G   G  GGGGG   G GGGGGGGGG  G
Sbjct: 444 GQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAG 476



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 17/28 (60%), Positives = 17/28 (60%)

Query: 64  GETGGGGGSALGPGGGGGGGGGGGGGGP 91
           G  GGGGG   G GGGGGGGG  G   P
Sbjct: 453 GGGGGGGGGGGGGGGGGGGGGEAGAVAP 480


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,128,540
Number of Sequences: 37866
Number of extensions: 1379229
Number of successful extensions: 38314
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 759
Number of HSP's successfully gapped in prelim test: 263
Number of HSP's that attempted gapping in prelim test: 16753
Number of HSP's gapped (non-prelim): 10353
length of query: 557
length of database: 18,247,518
effective HSP length: 107
effective length of query: 450
effective length of database: 14,195,856
effective search space: 6388135200
effective search space used: 6388135200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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