Search of human proteins with 187761337

Search of human proteins with 187761337

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
         (416 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187761337 transmembrane protease, serine 11B [Homo sapiens]        857   0.0  
gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo ...   322   5e-88
gi|194018492 transmembrane protease, serine 11F [Homo sapiens]        320   1e-87
gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo ...   318   7e-87
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]       315   6e-86
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          315   6e-86
gi|40254871 transmembrane protease, serine 11E [Homo sapiens]         314   8e-86
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   202   5e-52
gi|4506153 prostasin preproprotein [Homo sapiens]                     199   3e-51
gi|148613878 acrosin precursor [Homo sapiens]                         192   5e-49
gi|33695155 hepsin [Homo sapiens]                                     191   1e-48
gi|4504481 hepsin [Homo sapiens]                                      191   1e-48
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...   191   1e-48
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...   191   1e-48
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]          191   1e-48
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa...   187   2e-47
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap...   187   2e-47
gi|222831592 transmembrane protease, serine 7 [Homo sapiens]          185   6e-47
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         185   8e-47
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             182   4e-46
gi|223942069 enterokinase precursor [Homo sapiens]                    182   6e-46
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]           182   6e-46
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      180   2e-45
gi|13994276 marapsin [Homo sapiens]                                   180   2e-45
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           180   2e-45
gi|110815798 ovochymase 1 [Homo sapiens]                              180   2e-45
gi|11415040 matriptase [Homo sapiens]                                 177   1e-44
gi|5803197 testisin isoform 1 [Homo sapiens]                          176   5e-44
gi|21614531 testisin isoform 2 [Homo sapiens]                         174   1e-43
gi|29244926 corin [Homo sapiens]                                      174   1e-43

>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
          Length = 416

 Score =  857 bits (2213), Expect = 0.0
 Identities = 416/416 (100%), Positives = 416/416 (100%)

Query: 1   MYRHGISSQRSWPLWTTIFIFLGVAAILGVTIGLLVHFLAVEKTYYYQGDFHISGVTYND 60
           MYRHGISSQRSWPLWTTIFIFLGVAAILGVTIGLLVHFLAVEKTYYYQGDFHISGVTYND
Sbjct: 1   MYRHGISSQRSWPLWTTIFIFLGVAAILGVTIGLLVHFLAVEKTYYYQGDFHISGVTYND 60

Query: 61  NCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKFKFP 120
           NCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKFKFP
Sbjct: 61  NCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKFKFP 120

Query: 121 PAEGVSMRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVANSII 180
           PAEGVSMRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVANSII
Sbjct: 121 PAEGVSMRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVANSII 180

Query: 181 TGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNF 240
           TGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNF
Sbjct: 181 TGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNF 240

Query: 241 GIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSE 300
           GIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSE
Sbjct: 241 GIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSE 300

Query: 301 NDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEAD 360
           NDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEAD
Sbjct: 301 NDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEAD 360

Query: 361 ACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTGL 416
           ACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTGL
Sbjct: 361 ACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTGL 416


>gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo
           sapiens]
          Length = 418

 Score =  322 bits (824), Expect = 5e-88
 Identities = 171/423 (40%), Positives = 248/423 (58%), Gaps = 13/423 (3%)

Query: 1   MYR---HGISSQRSWPLWTTIFIFLGVAAILGVTIGLLVHFLAVE-KTYYYQGDFHISGV 56
           MYR    G  S+   P    + I L +  ++ VTIGLLVHFL  + K  YY G F I   
Sbjct: 2   MYRTVGFGTRSRNLKPWMIAVLIVLSLT-VVAVTIGLLVHFLVFDQKKEYYHGSFKILDP 60

Query: 57  TYNDNCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLK 116
             N+N   + +    +L +  E  +   F +S+  K Y+K++V++L P  +G  V + + 
Sbjct: 61  QINNNFGQSNTYQLKDLRETTENLVDEIFIDSAWKKNYIKNQVVRLTPEEDGVKVDVIMV 120

Query: 117 FKFPPAEGVSMRTKIKAKLHQMLKNNMASWNAVP---ASIKLMEISKAASEMLTNNCCGR 173
           F+FP  E  ++R K   K+  +L   + +  A+P   +S+++  +S +  E+     CG+
Sbjct: 121 FQFPSTEQRAVREK---KIQSILNQKIRNLRALPINASSVQVNAMSSSTGELTVQASCGK 177

Query: 174 QVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNS 233
           +V    +  N+I +G  + + AWPWQAS+Q+   H CGA+LIS+ WL++AAHCF K  N 
Sbjct: 178 RVVP--LNVNRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQKYKNP 235

Query: 234 KDWTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPE 293
             WTV+FG  +N P M R V+  I HE Y S     DIA+VQ++  V+F++ IR+ICLPE
Sbjct: 236 HQWTVSFGTKINPPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPE 295

Query: 294 AKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAG 353
           A      N  V +TG+G LY  G     L+E  +KII + +C     Y   +   M CAG
Sbjct: 296 ASASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMFCAG 355

Query: 354 FMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSK 413
           +M G  DAC+ DSGGPL   D ++ W+L+GIVSWGD CG+K+KPGVYT+VT YRNWI SK
Sbjct: 356 YMEGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWIASK 415

Query: 414 TGL 416
           TG+
Sbjct: 416 TGI 418


>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
          Length = 438

 Score =  320 bits (821), Expect = 1e-87
 Identities = 166/421 (39%), Positives = 247/421 (58%), Gaps = 14/421 (3%)

Query: 9   QRSWPLWTTI---FIFLGVAAILGVTIGLLVHFLAVE-KTYYYQGDFHISGVTYNDNCEN 64
           QR    W ++      L + AI+G+ IG++ HF+  + K++YY   F ++ + Y +N   
Sbjct: 19  QRKQQFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFYYLASFKVTNIKYKENYGI 78

Query: 65  AASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKFKFPPAEG 124
            +S+     S  IE  M   F++SS+   ++KS VIKL P+  G ++ + L F++P  + 
Sbjct: 79  RSSREFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDEQGVDILIVLIFRYPSTDS 138

Query: 125 VS-MRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVANSII--- 180
              ++ KI+  L+Q LK    S      S +L  I       L N+ CG ++ +S +   
Sbjct: 139 AEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLP 198

Query: 181 ---TGNKIVNGK-SSLEGAWPWQASMQWKGR-HYCGASLISSRWLLSAAHCFAKKNNSKD 235
              +  +IV G+ +++EG WPWQAS+Q  G  H CGASLIS+ WLL+AAHCF K  +   
Sbjct: 199 ASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQ 258

Query: 236 WTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAK 295
           W   FG  +  P + R V+ II HENY      +DIALVQL+  V F+  ++++CLP++ 
Sbjct: 259 WIATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSS 318

Query: 296 MKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFM 355
           +KL    +V VTG+G++  +G     L++  ++ I   +CN    Y G +T  MLCAGFM
Sbjct: 319 IKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFM 378

Query: 356 SGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTG 415
            G+ DAC+ DSGGPL Y D+ +IW++VGIVSWG  C    KPGVYTRVT YR+WI SKTG
Sbjct: 379 EGKIDACKGDSGGPLVY-DNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWIASKTG 437

Query: 416 L 416
           +
Sbjct: 438 M 438


>gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo
           sapiens]
          Length = 421

 Score =  318 bits (814), Expect = 7e-87
 Identities = 171/426 (40%), Positives = 250/426 (58%), Gaps = 16/426 (3%)

Query: 1   MYR---HGISSQRSWPLWTTIFIFLGVAAILGVTIGLLVHFLAVE-KTYYYQGDFHISGV 56
           MYR    G  S+   P    + I L +  ++ VTIGLLVHFL  + K  YY G F I   
Sbjct: 2   MYRTVGFGTRSRNLKPWMIAVLIVLSLT-VVAVTIGLLVHFLVFDQKKEYYHGSFKILDP 60

Query: 57  TYNDNCENAASQASTNLSKDIE---TKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQL 113
             N+N   + +    +L +  E   +++   F +S+  K Y+K++V++L P  +G  V +
Sbjct: 61  QINNNFGQSNTYQLKDLRETTENLVSQVDEIFIDSAWKKNYIKNQVVRLTPEEDGVKVDV 120

Query: 114 QLKFKFPPAEGVSMRTKIKAKLHQMLKNNMASWNAVP---ASIKLMEISKAASEMLTNNC 170
            + F+FP  E  ++R K   K+  +L   + +  A+P   +S+++  +S +  E+     
Sbjct: 121 IMVFQFPSTEQRAVREK---KIQSILNQKIRNLRALPINASSVQVNAMSSSTGELTVQAS 177

Query: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK 230
           CG++V    +  N+I +G  + + AWPWQAS+Q+   H CGA+LIS+ WL++AAHCF K 
Sbjct: 178 CGKRVVP--LNVNRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQKY 235

Query: 231 NNSKDWTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKIC 290
            N   WTV+FG  +N P M R V+  I HE Y S     DIA+VQ++  V+F++ IR+IC
Sbjct: 236 KNPHQWTVSFGTKINPPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQIC 295

Query: 291 LPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTML 350
           LPEA      N  V +TG+G LY  G     L+E  +KII + +C     Y   +   M 
Sbjct: 296 LPEASASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMF 355

Query: 351 CAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410
           CAG+M G  DAC+ DSGGPL   D ++ W+L+GIVSWGD CG+K+KPGVYT+VT YRNWI
Sbjct: 356 CAGYMEGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWI 415

Query: 411 TSKTGL 416
            SKTG+
Sbjct: 416 ASKTGI 421


>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
          Length = 423

 Score =  315 bits (806), Expect = 6e-86
 Identities = 165/422 (39%), Positives = 237/422 (56%), Gaps = 6/422 (1%)

Query: 1   MYRHGISSQRS---WPLWTTIFIFLGVAAILGVTIGLLVHFLAV--EKTYYYQGDFHISG 55
           MYR  +   R    W  W    +      +L V IGL VH++    +KTY Y      + 
Sbjct: 2   MYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTT 61

Query: 56  VTYNDNCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQL 115
                     AS   T +S+ +E+ + NAF  S + +E+VKS+VIK     +G    + L
Sbjct: 62  DKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLL 121

Query: 116 KFKFPPAEGVSMRTKI-KAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQ 174
             +F   E      KI +  LH+ L++ +      P S+K+ +I+K  ++   N+CCG +
Sbjct: 122 ICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPQSVKIKKINKTETDSYLNHCCGTR 181

Query: 175 VANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSK 234
            + ++    +IV G    EG WPWQAS+QW G H CGA+LI++ WL+SAAHCF    N  
Sbjct: 182 RSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPA 241

Query: 235 DWTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEA 294
            WT +FG+ +    M R ++ II HE Y  P    DI+L +L+  V +T  + ++CLP+A
Sbjct: 242 RWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDA 301

Query: 295 KMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGF 354
             +    D + VTG+G L  +G     L++  + +ID   CN   AY+  +T  MLCAG 
Sbjct: 302 SYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGS 361

Query: 355 MSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKT 414
           + G+ DACQ DSGGPL   D+R+IW+L GIVSWGD C K NKPGVYTRVT+ R+WITSKT
Sbjct: 362 LEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKT 421

Query: 415 GL 416
           G+
Sbjct: 422 GI 423


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  315 bits (806), Expect = 6e-86
 Identities = 165/420 (39%), Positives = 242/420 (57%), Gaps = 6/420 (1%)

Query: 1   MYRHG--ISSQRSWPLWTTIFIFLGVAAILGVTIGLLVHFLAVE-KTYYYQGDFHISGVT 57
           MYR     S+ R    +   FI +    IL VTI LLV+FLA + K+Y+Y+  F +  V 
Sbjct: 1   MYRPARVTSTSRFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVE 60

Query: 58  YNDNCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKF 117
           YN    + A+Q    LS  IE+ +   F+ S++  +++++ V KL  + +G    + +KF
Sbjct: 61  YNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKF 120

Query: 118 KFPPAE-GVSMRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVA 176
           +F     G SM+++I++ L QML NN  +    P++       +AA+  L N C G    
Sbjct: 121 QFTRNNNGASMKSRIESVLRQML-NNSGNLEINPSTEITSLTDQAAANWLINEC-GAGPD 178

Query: 177 NSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDW 236
              ++  +I+ G  + EG+WPWQ S++    H+CG SLI++ W+L+AAHCF   +N +DW
Sbjct: 179 LITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDW 238

Query: 237 TVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKM 296
               GI    P +  +V+NI+ H NY S    +DIALV+L   V+FT+ I  +CLP A  
Sbjct: 239 IATSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQ 298

Query: 297 KLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMS 356
            +       VTGWG     G     L++  ++II N +CNA ++Y+G +   MLCAG   
Sbjct: 299 NIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQ 358

Query: 357 GEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTGL 416
           G  DACQ DSGGPL   DSR +W +VGIVSWGD CG  +KPGVYTRVT+Y +WI  +TG+
Sbjct: 359 GGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTGI 418


>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
          Length = 423

 Score =  314 bits (805), Expect = 8e-86
 Identities = 165/422 (39%), Positives = 237/422 (56%), Gaps = 6/422 (1%)

Query: 1   MYRHGISSQRS---WPLWTTIFIFLGVAAILGVTIGLLVHFLAV--EKTYYYQGDFHISG 55
           MYR  +   R    W  W    +      +L V IGL VH++    +KTY Y      + 
Sbjct: 2   MYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTT 61

Query: 56  VTYNDNCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQL 115
                     AS   T +S+ +E+ + NAF  S + +E+VKS+VIK     +G    + L
Sbjct: 62  DKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLL 121

Query: 116 KFKFPPAEGVSMRTKI-KAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQ 174
             +F   E      KI +  LH+ L++ +      P S+K+ +I+K  ++   N+CCG +
Sbjct: 122 ICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGTR 181

Query: 175 VANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSK 234
            + ++    +IV G    EG WPWQAS+QW G H CGA+LI++ WL+SAAHCF    N  
Sbjct: 182 RSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPA 241

Query: 235 DWTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEA 294
            WT +FG+ +    M R ++ II HE Y  P    DI+L +L+  V +T  + ++CLP+A
Sbjct: 242 RWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDA 301

Query: 295 KMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGF 354
             +    D + VTG+G L  +G     L++  + +ID   CN   AY+  +T  MLCAG 
Sbjct: 302 SYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGS 361

Query: 355 MSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKT 414
           + G+ DACQ DSGGPL   D+R+IW+L GIVSWGD C K NKPGVYTRVT+ R+WITSKT
Sbjct: 362 LEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKT 421

Query: 415 GL 416
           G+
Sbjct: 422 GI 423


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  202 bits (514), Expect = 5e-52
 Identities = 103/255 (40%), Positives = 152/255 (59%), Gaps = 10/255 (3%)

Query: 161 AASEMLTNNC--CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSR 218
           A+  ++T  C  CG +   S    ++IV G  SL   WPWQAS+Q++G H CG S+I+  
Sbjct: 195 ASGHVVTLQCTACGHRRGYS----SRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPL 250

Query: 219 WLLSAAHCFAKKNNSKDWTVNFGIV--VNKPYMTRKVQNIIFHENYSSPGLHDDIALVQL 276
           W+++AAHC       K WT+  G+V  ++ P  +  V+ I++H  Y    L +DIAL++L
Sbjct: 251 WIITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKL 310

Query: 277 AEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWG-TLYMNGSFPVILQEDFLKIIDNKIC 335
           A  ++F E I+ +CLP ++    +      +GWG T    G    +L    + +I NKIC
Sbjct: 311 AGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKIC 370

Query: 336 NASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKN 395
           N    Y G ++ +MLCAG+++G  D+CQ DSGGPL   + R +W LVG  S+G GC + N
Sbjct: 371 NHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQE-RRLWKLVGATSFGIGCAEVN 429

Query: 396 KPGVYTRVTSYRNWI 410
           KPGVYTRVTS+ +WI
Sbjct: 430 KPGVYTRVTSFLDWI 444


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  199 bits (507), Expect = 3e-51
 Identities = 101/242 (41%), Positives = 142/242 (58%), Gaps = 13/242 (5%)

Query: 184 KIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIV 243
           +I  G S++ G WPWQ S+ ++G H CG SL+S +W+LSAAHCF  +++ + + V  G  
Sbjct: 44  RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAH 103

Query: 244 VNKPY----MTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLS 299
               Y        +++II H +Y   G   DIAL+QL+  ++F+ YIR ICLP A     
Sbjct: 104 QLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFP 163

Query: 300 ENDNVVVTGWGTLYMNGSF--PVILQEDFLKIIDNKICNASYAYSG------FVTDTMLC 351
              +  VTGWG +  + S   P  LQ+  + +I  + CN  Y          FV + M+C
Sbjct: 164 NGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVC 223

Query: 352 AGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWIT 411
           AG++ G  DACQ DSGGPL+ P    +W+L GIVSWGD CG +N+PGVYT  +SY +WI 
Sbjct: 224 AGYVEGGKDACQGDSGGPLSCP-VEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQ 282

Query: 412 SK 413
           SK
Sbjct: 283 SK 284


>gi|148613878 acrosin precursor [Homo sapiens]
          Length = 421

 Score =  192 bits (488), Expect = 5e-49
 Identities = 111/283 (39%), Positives = 154/283 (54%), Gaps = 18/283 (6%)

Query: 151 ASIKLMEISKAASEMLT-NNCCGRQVANSIITGNKIVNGKSSLEGAWPWQASMQW----- 204
           A + ++ +S  A +  T +  CG +   +   G +IV GK++  GAWPW  S+Q      
Sbjct: 8   AILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNS 67

Query: 205 KGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIV---------VNKPYMTRKVQN 255
              H CG SL++SRW+L+AAHCF  KNN  DW + FG           V  P   R V+ 
Sbjct: 68  HRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEK 127

Query: 256 IIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSE-NDNVVVTGWGTLYM 314
           II HE Y+S    +DIALV++   +S   +I   CLP  K  L   + +  V GWG +  
Sbjct: 128 IIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEE 187

Query: 315 NGSFPV-ILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYP 373
               P  IL E  + +ID  +CN++  Y+G V  T +CAG+  G+ D CQ DSGGPL   
Sbjct: 188 KAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCK 247

Query: 374 DSR-NIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTG 415
           DS+ + + +VGI SWG GC +  +PG+YT    Y NWI SK G
Sbjct: 248 DSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 290


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  191 bits (485), Expect = 1e-48
 Identities = 103/252 (40%), Positives = 139/252 (55%), Gaps = 16/252 (6%)

Query: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK 230
           CGR+     +  ++IV G+ +  G WPWQ S+++ G H CG SL+S  W+L+AAHCF ++
Sbjct: 153 CGRRK----LPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPER 208

Query: 231 NNSKD-WTVNFGIVVN-KPY-MTRKVQNIIFHENY------SSPGLHDDIALVQLAEEVS 281
           N     W V  G V    P+ +   VQ +++H  Y      +S    +DIALV L+  + 
Sbjct: 209 NRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLP 268

Query: 282 FTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAY 341
            TEYI+ +CLP A   L +     VTGWG     G    +LQE  + II N +CN +  Y
Sbjct: 269 LTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFY 328

Query: 342 SGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRN---IWHLVGIVSWGDGCGKKNKPG 398
              +   M CAG+  G  DACQ DSGGP    DS +    W L GIVSWG GC    KPG
Sbjct: 329 GNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPG 388

Query: 399 VYTRVTSYRNWI 410
           VYT+V+ +R WI
Sbjct: 389 VYTKVSDFREWI 400


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  191 bits (485), Expect = 1e-48
 Identities = 103/252 (40%), Positives = 139/252 (55%), Gaps = 16/252 (6%)

Query: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK 230
           CGR+     +  ++IV G+ +  G WPWQ S+++ G H CG SL+S  W+L+AAHCF ++
Sbjct: 153 CGRRK----LPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPER 208

Query: 231 NNSKD-WTVNFGIVVN-KPY-MTRKVQNIIFHENY------SSPGLHDDIALVQLAEEVS 281
           N     W V  G V    P+ +   VQ +++H  Y      +S    +DIALV L+  + 
Sbjct: 209 NRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLP 268

Query: 282 FTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAY 341
            TEYI+ +CLP A   L +     VTGWG     G    +LQE  + II N +CN +  Y
Sbjct: 269 LTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFY 328

Query: 342 SGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRN---IWHLVGIVSWGDGCGKKNKPG 398
              +   M CAG+  G  DACQ DSGGP    DS +    W L GIVSWG GC    KPG
Sbjct: 329 GNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPG 388

Query: 399 VYTRVTSYRNWI 410
           VYT+V+ +R WI
Sbjct: 389 VYTKVSDFREWI 400


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score =  191 bits (484), Expect = 1e-48
 Identities = 91/233 (39%), Positives = 135/233 (57%), Gaps = 7/233 (3%)

Query: 183 NKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK-NNSKDWTVNFG 241
           ++IV G+S+L GAWPWQ S+  +  H CG S+I+  W+++AAHC  K  NN   WT   G
Sbjct: 291 SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAG 350

Query: 242 IVVNKPYMTR----KVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMK 297
           I+  + +M      +V+ +I H NY S   ++DIAL++L + ++F + ++ +CLP   M 
Sbjct: 351 IL-RQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMM 409

Query: 298 LSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSG 357
           L       ++GWG     G    +L    + +I+ + CN+ Y Y   +T  M+CAGF+ G
Sbjct: 410 LQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQG 469

Query: 358 EADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410
             D+CQ DSGGPL      NIW L+G  SWG GC K  +PGVY  V  + +WI
Sbjct: 470 NVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score =  191 bits (484), Expect = 1e-48
 Identities = 91/233 (39%), Positives = 135/233 (57%), Gaps = 7/233 (3%)

Query: 183 NKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK-NNSKDWTVNFG 241
           ++IV G+S+L GAWPWQ S+  +  H CG S+I+  W+++AAHC  K  NN   WT   G
Sbjct: 254 SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAG 313

Query: 242 IVVNKPYMTR----KVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMK 297
           I+  + +M      +V+ +I H NY S   ++DIAL++L + ++F + ++ +CLP   M 
Sbjct: 314 IL-RQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMM 372

Query: 298 LSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSG 357
           L       ++GWG     G    +L    + +I+ + CN+ Y Y   +T  M+CAGF+ G
Sbjct: 373 LQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQG 432

Query: 358 EADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410
             D+CQ DSGGPL      NIW L+G  SWG GC K  +PGVY  V  + +WI
Sbjct: 433 NVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score =  191 bits (484), Expect = 1e-48
 Identities = 96/256 (37%), Positives = 149/256 (58%), Gaps = 14/256 (5%)

Query: 168 NNCCGRQVANSIIT-------GNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWL 220
           NNC   QV +   +        ++IV G+S   G WPWQAS+    RH CG S+++ RW+
Sbjct: 194 NNCTSGQVVSLRCSECGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWV 253

Query: 221 LSAAHCFAKKNNSK--DWTVNFGIVVN---KPYMTRKVQNIIFHENYSSPGLHDDIALVQ 275
           ++AAHC      ++   W V+ G+V +   +P+    V+ II H  YS+     D+AL++
Sbjct: 254 VTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLR 313

Query: 276 LAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPV-ILQEDFLKIIDNKI 334
           L   ++F++ +  +CLP  +    +     V+GWG  + + ++   +LQ+  + +   ++
Sbjct: 314 LQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQL 373

Query: 335 CNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKK 394
           CN+S  YSG +T  MLCAG++ G ADACQ DSGGPL  PD  + W LVG+VSWG GC + 
Sbjct: 374 CNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDG-DTWRLVGVVSWGRGCAEP 432

Query: 395 NKPGVYTRVTSYRNWI 410
           N PGVY +V  + +WI
Sbjct: 433 NHPGVYAKVAEFLDWI 448


>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
           sapiens]
          Length = 432

 Score =  187 bits (474), Expect = 2e-47
 Identities = 99/270 (36%), Positives = 152/270 (56%), Gaps = 14/270 (5%)

Query: 153 IKLMEISKAASEMLTNNCCGRQVANSIITGN-----------KIVNGKSSLEGAWPWQAS 201
           + ++EI++ + E+   N  G  ++ S+++ +           ++V G+ +   +WPWQ S
Sbjct: 157 LDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVS 216

Query: 202 MQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIVVNKPYMTRKVQNIIFHEN 261
           +Q+  +H CG S++   W+L+AAHCF K  +  +W V  G      + +  V  II  E 
Sbjct: 217 IQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEF 276

Query: 262 YSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMN-GSFPV 320
                  +DIAL++L   ++F+  +R ICLP    +L+    + + GWG    N G    
Sbjct: 277 NPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSD 336

Query: 321 ILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWH 380
           IL +  +++ID+  CNA  AY G VT+ M+CAG   G  D CQ DSGGPL Y   +  WH
Sbjct: 337 ILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQ--WH 394

Query: 381 LVGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410
           +VGIVSWG GCG  + PGVYT+V++Y NWI
Sbjct: 395 VVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 424


>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
           sapiens]
          Length = 437

 Score =  187 bits (474), Expect = 2e-47
 Identities = 99/270 (36%), Positives = 152/270 (56%), Gaps = 14/270 (5%)

Query: 153 IKLMEISKAASEMLTNNCCGRQVANSIITGN-----------KIVNGKSSLEGAWPWQAS 201
           + ++EI++ + E+   N  G  ++ S+++ +           ++V G+ +   +WPWQ S
Sbjct: 162 LDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVS 221

Query: 202 MQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIVVNKPYMTRKVQNIIFHEN 261
           +Q+  +H CG S++   W+L+AAHCF K  +  +W V  G      + +  V  II  E 
Sbjct: 222 IQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEF 281

Query: 262 YSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMN-GSFPV 320
                  +DIAL++L   ++F+  +R ICLP    +L+    + + GWG    N G    
Sbjct: 282 NPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSD 341

Query: 321 ILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWH 380
           IL +  +++ID+  CNA  AY G VT+ M+CAG   G  D CQ DSGGPL Y   +  WH
Sbjct: 342 ILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQ--WH 399

Query: 381 LVGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410
           +VGIVSWG GCG  + PGVYT+V++Y NWI
Sbjct: 400 VVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 429


>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
          Length = 717

 Score =  185 bits (470), Expect = 6e-47
 Identities = 99/235 (42%), Positives = 141/235 (60%), Gaps = 10/235 (4%)

Query: 183 NKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCF--AKKNNSKDWTVNF 240
           ++I+ G  +LEG WPWQ S+ + G  YCGAS+IS  WLLSAAHCF   + ++   WT + 
Sbjct: 478 HRIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHL 537

Query: 241 GIVV-NKPYMTRKVQNIIFHENYSSPGLHDDIALVQL--AEEVSFTEYIRKICLPEAKMK 297
           G+ V         V+ I+ HE Y+S     DIAL+QL  A   +  + I+ IC+P    +
Sbjct: 538 GMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPTGQR 597

Query: 298 LSENDNVVVTGWGTLY-MNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMS 356
           +   +   VTGWG  +  +    ++LQ+  +++ID  +C ++Y   G +T  MLCAG MS
Sbjct: 598 VRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTY---GIITSRMLCAGIMS 654

Query: 357 GEADACQNDSGGPLA-YPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410
           G+ DAC+ DSGGPL+    S   W L GIVSWG G G+ N PGVYTRV+++  WI
Sbjct: 655 GKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWI 709


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  185 bits (469), Expect = 8e-47
 Identities = 100/254 (39%), Positives = 147/254 (57%), Gaps = 21/254 (8%)

Query: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK 230
           CG +  ++++ G     G  S  G WPWQAS++ + RH CG SL+S RW+LSAAHCF K 
Sbjct: 46  CGHREIHALVAG-----GVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKH 100

Query: 231 NNSKDWTVNFGIVVNKP-------YMTR-KVQNIIFHENYSSPGLHDDIALVQLAEEVSF 282
               +WTV  G + ++P       Y +R KVQ+II + + +   L +DIAL++LA  V++
Sbjct: 101 YYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPD-ALGVLRNDIALLRLASSVTY 159

Query: 283 TEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGS---FPVILQEDFLKIIDNKICNASY 339
             YI+ IC+  +        +  VTGWG +  +G+    P  L+E  + I++N  CN  +
Sbjct: 160 NAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLF 219

Query: 340 ---AYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNK 396
              +    + D+M CAG   G  D C+ DSGGPL   D   +W+ VGIVSWG  CG+ N+
Sbjct: 220 EQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVC-DKDGLWYQVGIVSWGMDCGQPNR 278

Query: 397 PGVYTRVTSYRNWI 410
           PGVYT ++ Y +WI
Sbjct: 279 PGVYTNISVYFHWI 292


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  182 bits (463), Expect = 4e-46
 Identities = 96/241 (39%), Positives = 135/241 (56%), Gaps = 9/241 (3%)

Query: 181 TGNKIVNGKSSLEGAWPWQASMQWK---GRHYCGASLISSRWLLSAAHCFAKKNNSKDWT 237
           T  +IV G +S  G WPWQ S+Q K    RH CG SLI  +W+L+AAHCF        W 
Sbjct: 387 TSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 446

Query: 238 VNFGIV----VNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPE 293
           +  GI+    + K     +++ II H+NY     + DIAL++L   +++TE+ + ICLP 
Sbjct: 447 IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPS 506

Query: 294 AKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAG 353
                +   N  VTGWG     G    ILQ+  + ++ N+ C   Y     +T  M+CAG
Sbjct: 507 KGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQ-DYKITQRMVCAG 565

Query: 354 FMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSK 413
           +  G  DAC+ DSGGPL    +  +W LVGI SWG+GC ++ +PGVYT+V  Y +WI  K
Sbjct: 566 YKEGGKDACKGDSGGPLVCKHN-GMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEK 624

Query: 414 T 414
           T
Sbjct: 625 T 625


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score =  182 bits (461), Expect = 6e-46
 Identities = 95/248 (38%), Positives = 141/248 (56%), Gaps = 9/248 (3%)

Query: 171  CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK 230
            CG+++A   IT  KIV G ++ EGAWPW   + + GR  CGASL+SS WL+SAAHC   +
Sbjct: 772  CGKKLAAQDITP-KIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGR 830

Query: 231  N-NSKDWTVNFGI-----VVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTE 284
            N     WT   G+     + +   + R +  I+ + +Y+     +DIA++ L  +V++T+
Sbjct: 831  NLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTD 890

Query: 285  YIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGF 344
            YI+ ICLPE         N  + GWGT+   G+   ILQE  + ++ N+ C         
Sbjct: 891  YIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYN- 949

Query: 345  VTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVT 404
            +T+ M+CAG+  G  D+CQ DSGGPL   ++ N W L G+ S+G  C   N+PGVY RV+
Sbjct: 950  ITENMICAGYEEGGIDSCQGDSGGPLMCQEN-NRWFLAGVTSFGYKCALPNRPGVYARVS 1008

Query: 405  SYRNWITS 412
             +  WI S
Sbjct: 1009 RFTEWIQS 1016



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 36/129 (27%), Positives = 64/129 (49%), Gaps = 8/129 (6%)

Query: 18  IFIFLGVAAILGVTIGLLVHFLAVEKTYYYQGDFHI-SGVTYNDNCENAASQASTNLSKD 76
           + +  G+ A+  +TI       A+ +++  +  F I SGVTYN N ++  S     L+ D
Sbjct: 29  VVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFD 88

Query: 77  IETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKFKFPPAEGVSMRTKIKAKLH 136
           ++  +   F +S++  EY  S V++     NGS +   + F    A+ VS    +K +L 
Sbjct: 89  LQQMIDEIFLSSNLKNEYKNSRVLQF---ENGSII---VVFDLFFAQWVS-DENVKEELI 141

Query: 137 QMLKNNMAS 145
           Q L+ N +S
Sbjct: 142 QGLEANKSS 150


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score =  182 bits (461), Expect = 6e-46
 Identities = 98/248 (39%), Positives = 150/248 (60%), Gaps = 16/248 (6%)

Query: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK 230
           CG + A    T  ++V G  +  G  PWQ S++   RH+CGA+++  RWLLSAAHCF   
Sbjct: 492 CGARPAMEKPT--RVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCF--- 546

Query: 231 NNSKDWTVNFGIV------VNKPYMTRKVQNIIFHENYSSPGLHD-DIALVQLAEEVSFT 283
           N++K   V   +       +    +   ++ ++ H  Y+ PG+ D D+A+++LA  ++F 
Sbjct: 547 NHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYN-PGILDFDLAVLELASPLAFN 605

Query: 284 EYIRKICLPEAKMKLSENDNVVVTGWG-TLYMNGSFPVILQEDFLKIIDNKICNASYAYS 342
           +YI+ +CLP A  K       +++GWG T   N + P +LQ+  + IID K C+  Y +S
Sbjct: 606 KYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFS 665

Query: 343 GFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTR 402
             +TD M+CAGF+ G+ D+CQ DSGGPLA  ++  +++L GIVSWG GC +  KPGVYTR
Sbjct: 666 --LTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTR 723

Query: 403 VTSYRNWI 410
           +T  + WI
Sbjct: 724 ITRLKGWI 731



 Score =  176 bits (447), Expect = 3e-44
 Identities = 90/251 (35%), Positives = 142/251 (56%), Gaps = 13/251 (5%)

Query: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK 230
           CG Q A  +    +IV G  +  G +PWQAS++    H+CGA++I++RWL+SAAHCF + 
Sbjct: 191 CGLQPAWRM--AGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEF 248

Query: 231 NNSKDWTVNFGIVV----NKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYI 286
            +   W    G           +  +V  I+ H  Y++     D+A+++L   + F  +I
Sbjct: 249 QDPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHI 308

Query: 287 RKICLPEAKMKLSENDNVVVTGWGTLYMNGSF---PVILQEDFLKIIDNKICNASYAYSG 343
           + +CLP A      +   +++GWG  Y+   F   P +LQ+  ++++D  +C + Y +S 
Sbjct: 309 QPVCLPAATHIFPPSKKCLISGWG--YLKEDFLVKPEVLQKATVELLDQALCASLYGHS- 365

Query: 344 FVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRV 403
            +TD M+CAG++ G+ D+CQ DSGGPL   +    + L GIVSWG GC +  +PGVY RV
Sbjct: 366 -LTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARV 424

Query: 404 TSYRNWITSKT 414
           T  R+WI   T
Sbjct: 425 TRLRDWILEAT 435



 Score =  174 bits (442), Expect = 1e-43
 Identities = 91/234 (38%), Positives = 129/234 (55%), Gaps = 13/234 (5%)

Query: 184  KIVNGKSSLEGAWPWQASMQWKGR-HYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGI 242
            +IV G ++  G WPWQ S+  + R H CGA L++ RWLLSAAHCF    + K W    G 
Sbjct: 826  RIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGT 885

Query: 243  VVNKPYMT------RKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKM 296
                P+++       +V  I  H  Y+   L  D+AL++LA  V  +  +R ICLPE   
Sbjct: 886  ----PFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAP 941

Query: 297  KLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMS 356
            +  +    V+TGWG++   GS    LQ+  ++++  + C   Y     ++  MLCAGF  
Sbjct: 942  RPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQ--ISSRMLCAGFPQ 999

Query: 357  GEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410
            G  D+C  D+GGPLA  +    W L G+ SWG GCG+ + PGVYTRV + R WI
Sbjct: 1000 GGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWI 1053


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  180 bits (457), Expect = 2e-45
 Identities = 106/249 (42%), Positives = 143/249 (57%), Gaps = 18/249 (7%)

Query: 171 CGR-QVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAK 229
           CGR QV+++   G +IV G ++  GAWPWQAS++ +  H CG SL+S +W+L+AAHCF+ 
Sbjct: 26  CGRPQVSDA---GGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSG 82

Query: 230 KNNSKDWTVNFG---IVVNKPYMTRKVQNIIFHENYS-SPGLHDDIALVQLAEEVSFTEY 285
             NS D+ V+ G   I ++  + T  V+ II H + S  PG   DIALV+L+  V+ +  
Sbjct: 83  SLNSSDYQVHLGELEITLSPHFST--VRQIILHSSPSGQPGTSGDIALVELSVPVTLSSR 140

Query: 286 IRKICLPEAKMKLSENDNVVVTGWGTLYMNGSF--PVILQEDFLKIIDNKICNASYAYSG 343
           I  +CLPEA           VTGWG          P  L+E  + ++D + C   Y   G
Sbjct: 141 ILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPG 200

Query: 344 --FVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYT 401
              +   MLCA    G  DACQ+DSGGPL        W   GIVSWG+GCG+ N+PGVYT
Sbjct: 201 GSILQPDMLCA---RGPGDACQDDSGGPLVC-QVNGAWVQAGIVSWGEGCGRPNRPGVYT 256

Query: 402 RVTSYRNWI 410
           RV +Y NWI
Sbjct: 257 RVPAYVNWI 265


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  180 bits (456), Expect = 2e-45
 Identities = 103/269 (38%), Positives = 148/269 (55%), Gaps = 20/269 (7%)

Query: 161 AASEMLTNNCCGRQVANSIITG------NKIVNGKSSLEGAWPWQASMQWKGRHYCGASL 214
           AA  +L   C G Q A +          N++V G+ + EG WPWQ S+Q  G H+CG SL
Sbjct: 5   AAVPLLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSL 64

Query: 215 ISSRWLLSAAHCFAKKNNSKDWTVNFG---IVVNKPY-MTRKVQNIIFHENYSSPGLHDD 270
           I+ +W+L+AAHCF   + +  + V  G   +V   P+ M  +V+ +  +  Y       D
Sbjct: 65  IAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSAD 124

Query: 271 IALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPV--ILQEDFLK 328
           +ALV+L   V FT YI  +CLP+  +      N  VTGWG+       P   ILQ+  + 
Sbjct: 125 VALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVP 184

Query: 329 IIDNKICNASYAYS---GF----VTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHL 381
           IID   CN  Y+     G+    + + MLCAGF  G+ DAC+ DSGGPL     ++ W  
Sbjct: 185 IIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS-WLQ 243

Query: 382 VGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410
            G++SWG+GC ++N+PGVY RVT++ NWI
Sbjct: 244 AGVISWGEGCARQNRPGVYIRVTAHHNWI 272


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  180 bits (456), Expect = 2e-45
 Identities = 98/246 (39%), Positives = 134/246 (54%), Gaps = 13/246 (5%)

Query: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK 230
           CG Q  +S     +IV G  S EG WPWQAS+Q +GRH CG +LI+ RW+++AAHCF + 
Sbjct: 568 CGLQGPSS-----RIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQED 622

Query: 231 NNSKD--WTVNFGIVVNKPY----MTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTE 284
           + +    WTV  G V         ++ KV  ++ H  +       D+AL+QL   V  + 
Sbjct: 623 SMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSA 682

Query: 285 YIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGF 344
            +R +CLP          +  +TGWG L   G     LQ+  +++I   +C+  Y Y   
Sbjct: 683 AVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQ-- 740

Query: 345 VTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVT 404
           VT  MLCAG+  G+ DACQ DSGGPL        W L G+VSWG GCG+ N  GVYTR+T
Sbjct: 741 VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRIT 800

Query: 405 SYRNWI 410
              +WI
Sbjct: 801 GVISWI 806


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score =  180 bits (456), Expect = 2e-45
 Identities = 89/255 (34%), Positives = 143/255 (56%), Gaps = 7/255 (2%)

Query: 166 LTNNCCGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAH 225
           + ++ CG    +      +I  G+ +    WPWQ  +++ G + CG ++I+  W+L+AAH
Sbjct: 556 ILHDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAH 615

Query: 226 CFAKKNNSKDWTVNFGI----VVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVS 281
           C   KNN   WT+  G     +       R+ ++II HE++++     DIAL+QL+  + 
Sbjct: 616 CVQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLE 675

Query: 282 FTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASY-- 339
           +   +R +CLP +   L  ++   VTGWG++  +G     LQ+  + +++ ++C  +Y  
Sbjct: 676 YNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYS 735

Query: 340 AYSGFVTDTMLCAGF-MSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPG 398
           A+ G +T+ M+CAGF  SGE D CQ DSGGPL        + L GIVSWG GC +  KPG
Sbjct: 736 AHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPG 795

Query: 399 VYTRVTSYRNWITSK 413
           V+ RV  + +WI SK
Sbjct: 796 VFARVMIFLDWIQSK 810



 Score =  127 bits (318), Expect = 2e-29
 Identities = 84/255 (32%), Positives = 124/255 (48%), Gaps = 21/255 (8%)

Query: 183 NKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCF--AKKNNSKDWTVNF 240
           ++I + ++S     PWQ S++    H+CG SLI    +++AAHC     +   K+ TV  
Sbjct: 45  SRISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTS 104

Query: 241 G----IVVNKPYMTRKVQNIIFHENYSSPG-LHDDIALVQLAEEVSFTEYIRKICLPEAK 295
           G       +K      V  II H  Y+S   +  DIAL+ L  +V F   ++ ICLP++ 
Sbjct: 105 GEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSD 164

Query: 296 MKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGF--VTDTMLCAG 353
            K+      + +GWG +     +  +LQE  L I+D++ CN          +  TMLCAG
Sbjct: 165 DKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAG 224

Query: 354 FMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKP----------GVYTRV 403
           F     DACQ DSGGPL       IW L GI SW  GC   + P          G++++V
Sbjct: 225 FPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKV 284

Query: 404 TSYRNWITSK--TGL 416
           +   ++IT    TGL
Sbjct: 285 SELMDFITQNLFTGL 299


>gi|11415040 matriptase [Homo sapiens]
          Length = 855

 Score =  177 bits (450), Expect = 1e-44
 Identities = 91/244 (37%), Positives = 136/244 (55%), Gaps = 13/244 (5%)

Query: 184 KIVNGKSSLEGAWPWQASMQWKGR-HYCGASLISSRWLLSAAHCFA-----KKNNSKDWT 237
           ++V G  + EG WPWQ S+   G+ H CGASLIS  WL+SAAHC+      + ++   WT
Sbjct: 614 RVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWT 673

Query: 238 VNFGIVVNKP-----YMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLP 292
              G+             R+++ II H  ++      DIAL++L +   ++  +R ICLP
Sbjct: 674 AFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLP 733

Query: 293 EAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCA 352
           +A         + VTGWG     G+  +ILQ+  +++I+   C         +T  M+C 
Sbjct: 734 DASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLLPQQ--ITPRMMCV 791

Query: 353 GFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITS 412
           GF+SG  D+CQ DSGGPL+  ++       G+VSWGDGC ++NKPGVYTR+  +R+WI  
Sbjct: 792 GFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIKE 851

Query: 413 KTGL 416
            TG+
Sbjct: 852 NTGV 855


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  176 bits (445), Expect = 5e-44
 Identities = 100/256 (39%), Positives = 143/256 (55%), Gaps = 23/256 (8%)

Query: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK 230
           CGR+V  S     +IV G+ +  G WPWQ S++    H CG SL+S RW L+AAHCF   
Sbjct: 33  CGRRVITS-----RIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETY 87

Query: 231 NNSKD---WTVNFGIVVNKP-------YMTRK-VQNIIFHENYSSPGLHDDIALVQLAEE 279
           ++  D   W V FG + + P       Y TR  V NI     Y     + DIALV+L+  
Sbjct: 88  SDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPY-DIALVKLSAP 146

Query: 280 VSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPV--ILQEDFLKIIDNKICN- 336
           V++T++I+ ICL  +  +     +  VTGWG +  + + P    LQE  + II+N +CN 
Sbjct: 147 VTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNH 206

Query: 337 --ASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKK 394
               Y++   +   M+CAG   G  DAC  DSGGPLA  +   +W+ +G+VSWG GCG+ 
Sbjct: 207 LFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLAC-NKNGLWYQIGVVSWGVGCGRP 265

Query: 395 NKPGVYTRVTSYRNWI 410
           N+PGVYT ++ +  WI
Sbjct: 266 NRPGVYTNISHHFEWI 281


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  174 bits (442), Expect = 1e-43
 Identities = 99/254 (38%), Positives = 142/254 (55%), Gaps = 21/254 (8%)

Query: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCF-AK 229
           CGR+V  S     +IV G+ +  G WPWQ S++    H CG SL+S RW L+AAHCF   
Sbjct: 33  CGRRVITS-----RIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETD 87

Query: 230 KNNSKDWTVNFGIVVNKP-------YMTRK-VQNIIFHENYSSPGLHDDIALVQLAEEVS 281
            ++   W V FG + + P       Y TR  V NI     Y     + DIALV+L+  V+
Sbjct: 88  LSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPY-DIALVKLSAPVT 146

Query: 282 FTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPV--ILQEDFLKIIDNKICN--- 336
           +T++I+ ICL  +  +     +  VTGWG +  + + P    LQE  + II+N +CN   
Sbjct: 147 YTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLF 206

Query: 337 ASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNK 396
             Y++   +   M+CAG   G  DAC  DSGGPLA  +   +W+ +G+VSWG GCG+ N+
Sbjct: 207 LKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLAC-NKNGLWYQIGVVSWGVGCGRPNR 265

Query: 397 PGVYTRVTSYRNWI 410
           PGVYT ++ +  WI
Sbjct: 266 PGVYTNISHHFEWI 279


>gi|29244926 corin [Homo sapiens]
          Length = 1042

 Score =  174 bits (441), Expect = 1e-43
 Identities = 103/282 (36%), Positives = 149/282 (52%), Gaps = 22/282 (7%)

Query: 135  LHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVANSIITGNKIVNGKSSLEG 194
            LH++L N  +            E     S + T   CGR+ A  +    +I+ G++S  G
Sbjct: 765  LHELLVNGQSC-----------ESRSKISLLCTKQDCGRRPAARM--NKRILGGRTSRPG 811

Query: 195  AWPWQASMQWK-GRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIV-VNKPYM--- 249
             WPWQ S+Q +   H CG  LI+ +W+L+ AHCF  + N+  W V  GI  ++ P +   
Sbjct: 812  RWPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKVVLGINNLDHPSVFMQ 871

Query: 250  TRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGW 309
            TR V+ II H  YS   +  DI++V+L+E++S T Y+R +CLP  +  L  +    +TGW
Sbjct: 872  TRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVRPVCLPNPEQWLEPDTYCYITGW 931

Query: 310  GTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGP 369
            G  +M    P  LQE  ++II  + C  SY     +T  M+CAG+ SG  D+C  DSGGP
Sbjct: 932  G--HMGNKMPFKLQEGEVRIISLEHCQ-SYFDMKTITTRMICAGYESGTVDSCMGDSGGP 988

Query: 370  LAYPDSRNIWHLVGIVSWGDGC-GKKNKPGVYTRVTSYRNWI 410
            L        W L G+ SWG  C  K   PGVY+ V+ +  WI
Sbjct: 989  LVCEKPGGRWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVEWI 1030


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,031,499
Number of Sequences: 37866
Number of extensions: 600521
Number of successful extensions: 1945
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 159
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1284
Number of HSP's gapped (non-prelim): 194
length of query: 416
length of database: 18,247,518
effective HSP length: 105
effective length of query: 311
effective length of database: 14,271,588
effective search space: 4438463868
effective search space used: 4438463868
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.