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Search of human proteins with 113204622
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|113204622 stromal membrane-associated GTPase-activating
protein 1 isoform A [Homo sapiens]
(467 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|113204622 stromal membrane-associated GTPase-activating prote... 941 0.0
gi|21264558 stromal membrane-associated GTPase-activating protei... 877 0.0
gi|23943872 small ArfGAP2 [Homo sapiens] 362 e-100
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 103 4e-22
gi|187608516 centaurin, beta 2 [Homo sapiens] 102 7e-22
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 102 7e-22
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 102 7e-22
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 100 5e-21
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 99 8e-21
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 99 8e-21
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 99 1e-20
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 98 1e-20
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 98 2e-20
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 97 2e-20
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 97 4e-20
gi|6806913 centaurin, alpha 1 [Homo sapiens] 96 7e-20
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do... 94 3e-19
gi|8923763 centaurin-alpha 2 protein [Homo sapiens] 93 5e-19
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 92 1e-18
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 92 1e-18
gi|7661880 centaurin beta1 [Homo sapiens] 91 2e-18
gi|46094081 development and differentiation enhancing factor 1 [... 88 2e-17
gi|31543983 ADP-ribosylation factor GTPase activating protein 2 ... 82 8e-16
gi|214829714 ADP-ribosylation factor GTPase activating protein 3... 81 2e-15
gi|214829673 ADP-ribosylation factor GTPase activating protein 3... 80 4e-15
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 79 7e-15
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ... 79 7e-15
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 77 3e-14
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain... 77 3e-14
gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 75 1e-13
>gi|113204622 stromal membrane-associated GTPase-activating protein
1 isoform A [Homo sapiens]
Length = 467
Score = 941 bits (2433), Expect = 0.0
Identities = 467/467 (100%), Positives = 467/467 (100%)
Query: 1 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 60
MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH
Sbjct: 1 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 60
Query: 61 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 120
RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR
Sbjct: 61 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 120
Query: 121 DKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKE 180
DKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKE
Sbjct: 121 DKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKE 180
Query: 181 PEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLN 240
PEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLN
Sbjct: 181 PEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLN 240
Query: 241 DDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQL 300
DDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQL
Sbjct: 241 DDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQL 300
Query: 301 SKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVM 360
SKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVM
Sbjct: 301 SKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVM 360
Query: 361 GQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWS 420
GQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWS
Sbjct: 361 GQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWS 420
Query: 421 LSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK 467
LSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK
Sbjct: 421 LSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK 467
>gi|21264558 stromal membrane-associated GTPase-activating protein 1
isoform B [Homo sapiens]
Length = 440
Score = 877 bits (2267), Expect = 0.0
Identities = 440/467 (94%), Positives = 440/467 (94%), Gaps = 27/467 (5%)
Query: 1 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 60
MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH
Sbjct: 1 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 60
Query: 61 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 120
RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR
Sbjct: 61 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 120
Query: 121 DKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKE 180
DKYEKKKYYDKNAIAITN KEKEKKKEEKKREKE
Sbjct: 121 DKYEKKKYYDKNAIAITN---------------------------KEKEKKKEEKKREKE 153
Query: 181 PEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLN 240
PEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLN
Sbjct: 154 PEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLN 213
Query: 241 DDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQL 300
DDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQL
Sbjct: 214 DDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQL 273
Query: 301 SKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVM 360
SKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVM
Sbjct: 274 SKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVM 333
Query: 361 GQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWS 420
GQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWS
Sbjct: 334 GQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWS 393
Query: 421 LSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK 467
LSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK
Sbjct: 394 LSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK 440
>gi|23943872 small ArfGAP2 [Homo sapiens]
Length = 429
Score = 362 bits (928), Expect = e-100
Identities = 220/471 (46%), Positives = 281/471 (59%), Gaps = 57/471 (12%)
Query: 9 KAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHIS 68
K+ K +++Q +L+ LL EEDNK+CADC++KGPRWASWNIGVFICIRCAGIHRNLGVHIS
Sbjct: 4 KSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHIS 63
Query: 69 RVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKY 128
RVKSVNLDQWT EQIQCMQ+MGN KA LYEA LPE FRRPQ D AVE FIRDKYEKKKY
Sbjct: 64 RVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKY 123
Query: 129 YDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKEPEKPAKPL 188
D+ ++D N KEK+ K ++ E PEK +P+
Sbjct: 124 MDR--------------------------SLDINAFRKEKD-DKWKRGSEPVPEKKLEPV 156
Query: 189 TAEKL---QKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDI 245
EK+ QKK+ P+KS SPK A P +DLLGLD P + N T+ L DLD+
Sbjct: 157 VFEKVKMPQKKEDPQLPRKS-SPKSTA-PVMDLLGLDAPVACSIANSKTS-NTLEKDLDL 213
Query: 246 FGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSI 305
+ S P P++ + S P A + +V +L+LF E +KSEE+ KKQLSKDSI
Sbjct: 214 ---LASVPSPSS-SGSRKVVGSMPTAGSAGSVPE-NLNLFPEPGSKSEEIGKKQLSKDSI 268
Query: 306 LSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPS-------MGVPVPAAPGLIGN 358
LSLYG+ T Q T +FM P + + P A+ FP MG +P G++
Sbjct: 269 LSLYGSQT-PQMPTQAMFMAPAQMAY----PTAYPSFPGVTPPNSIMGSMMPPPVGMV-- 321
Query: 359 VMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQ--GGMVGQMGAPQSKFGLPQAQQ 416
+ M+ M MP G+MG Q +M +P ++ Q G M G PQ+ +G+ AQQ
Sbjct: 322 AQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQ 381
Query: 417 PQWSLSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK 467
QW+L+QM QQMAGM+ A +GQ S G +G ++ QTLS Q+WK
Sbjct: 382 LQWNLTQMTQQMAGMNFYGANGMMNYGQSMS---GGNGQAANQTLSPQMWK 429
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 103 bits (256), Expect = 4e-22
Identities = 55/146 (37%), Positives = 82/146 (56%), Gaps = 11/146 (7%)
Query: 4 RSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNL 63
RS ++K + N+ L + + N +C DC+A P WAS N+G +CI C+GIHR+L
Sbjct: 648 RSAKDKTRLGNQNAALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHL 707
Query: 64 GVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTD---QAVEFFIR 120
G H+SRV+S++LD W E + M MGN A ++E L + +P D + E +IR
Sbjct: 708 GAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGAL-GGYSKPGPDACREEKERWIR 766
Query: 121 DKYEKKKYYDKNAIAITNISSSDAPL 146
KYE+K + + + SSD PL
Sbjct: 767 AKYEQKLF-------LAPLPSSDVPL 785
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 102 bits (254), Expect = 7e-22
Identities = 48/111 (43%), Positives = 73/111 (65%), Gaps = 3/111 (2%)
Query: 30 NKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDM 89
N C DC PRWAS N+G+ +CI C+GIHR+LGVH S+V+S+ LD W E ++ M ++
Sbjct: 411 NASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCEL 470
Query: 90 GNTKARLLYEANLPE-NFRRPQTD--QAVEFFIRDKYEKKKYYDKNAIAIT 137
GN +YEAN+ + ++PQ Q E +IR KY ++K+ DK +I+++
Sbjct: 471 GNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLS 521
>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
Length = 804
Score = 102 bits (254), Expect = 7e-22
Identities = 48/127 (37%), Positives = 75/127 (59%), Gaps = 4/127 (3%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K++ ++ + L + N +C DCE + P WAS N+G +CI C+GIHRNLG
Sbjct: 543 SSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLG 602
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTD---QAVEFFIRD 121
H+SRV+S++LD W E I+ M +GN A ++E + + +P D + E +IR
Sbjct: 603 THLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEES-SQGRTKPSVDSTREEKERWIRA 661
Query: 122 KYEKKKY 128
KYE+K +
Sbjct: 662 KYEQKLF 668
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 102 bits (254), Expect = 7e-22
Identities = 48/127 (37%), Positives = 75/127 (59%), Gaps = 4/127 (3%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K++ ++ + L + N +C DCE + P WAS N+G +CI C+GIHRNLG
Sbjct: 596 SSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLG 655
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTD---QAVEFFIRD 121
H+SRV+S++LD W E I+ M +GN A ++E + + +P D + E +IR
Sbjct: 656 THLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEES-SQGRTKPSVDSTREEKERWIRA 714
Query: 122 KYEKKKY 128
KYE+K +
Sbjct: 715 KYEQKLF 721
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 99.8 bits (247), Expect = 5e-21
Identities = 52/138 (37%), Positives = 77/138 (55%), Gaps = 16/138 (11%)
Query: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
+L ++ N C DC PRWAS N+GV +CI C+GIHR+LGVH S+V+S+ LD W
Sbjct: 405 VLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDSWE 464
Query: 80 AEQIQCMQDMGNTKARLLYEANLP-ENFRRP---QTDQAVEFFIRDKYEKKKYYDKNAIA 135
E ++ M ++GN+ +YEA R+P + Q E +I+DKY +KK+ K
Sbjct: 465 PELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKDKYVEKKFLRK---- 520
Query: 136 ITNISSSDAPLQPLVSSP 153
AP+ P + +P
Sbjct: 521 --------APMAPALEAP 530
>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 9 [Homo sapiens]
Length = 684
Score = 99.0 bits (245), Expect = 8e-21
Identities = 46/128 (35%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 4 RSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNL 63
+S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+
Sbjct: 450 KSSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSF 509
Query: 64 GVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRP---QTDQAVEFFIR 120
G +SRV+S+ LD W E + M +GN A ++E + + +P T + E++IR
Sbjct: 510 GTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGS-SQGQTKPSIKSTREEKEWWIR 568
Query: 121 DKYEKKKY 128
KYE+K +
Sbjct: 569 SKYEEKLF 576
>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 10 [Homo sapiens]
Length = 684
Score = 99.0 bits (245), Expect = 8e-21
Identities = 46/128 (35%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 4 RSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNL 63
+S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+
Sbjct: 450 KSSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSF 509
Query: 64 GVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRP---QTDQAVEFFIR 120
G +SRV+S+ LD W E + M +GN A ++E + + +P T + E++IR
Sbjct: 510 GTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGS-SQGQTKPSIKSTREEKEWWIR 568
Query: 121 DKYEKKKY 128
KYE+K +
Sbjct: 569 SKYEEKLF 576
>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
Length = 663
Score = 98.6 bits (244), Expect = 1e-20
Identities = 46/126 (36%), Positives = 72/126 (57%), Gaps = 2/126 (1%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+LG
Sbjct: 428 SSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLG 487
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQAVEFFIRDK 122
+SRV+S+ LD W E + M +GN A ++E + + T + E +IR K
Sbjct: 488 TRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSK 547
Query: 123 YEKKKY 128
YE+K +
Sbjct: 548 YEEKLF 553
>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 4 [Homo sapiens]
Length = 663
Score = 98.2 bits (243), Expect = 1e-20
Identities = 46/126 (36%), Positives = 72/126 (57%), Gaps = 2/126 (1%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+LG
Sbjct: 428 SSKSKSQLTSQSKAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLG 487
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQAVEFFIRDK 122
+SRV+S+ LD W E + M +GN A ++E + + T + E +IR K
Sbjct: 488 TRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSK 547
Query: 123 YEKKKY 128
YE+K +
Sbjct: 548 YEEKLF 553
>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
protein 11 [Homo sapiens]
Length = 550
Score = 97.8 bits (242), Expect = 2e-20
Identities = 47/127 (37%), Positives = 73/127 (57%), Gaps = 4/127 (3%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+LG
Sbjct: 315 SSKSKSQLTSQSEAMALQSIQNMRGNSHCVDCETQNPKWASLNLGVLMCIECSGIHRSLG 374
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRP---QTDQAVEFFIRD 121
+SRV+S+ LD W E + M +GN A ++E + + +P T + E +IR
Sbjct: 375 TRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGS-SQGQTKPSIESTREEKERWIRS 433
Query: 122 KYEKKKY 128
KYE K +
Sbjct: 434 KYEHKLF 440
>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
Length = 686
Score = 97.4 bits (241), Expect = 2e-20
Identities = 46/126 (36%), Positives = 72/126 (57%), Gaps = 2/126 (1%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+LG
Sbjct: 451 SSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLG 510
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQAVEFFIRDK 122
H+SRV+S+ LD W E + M + N A ++E + + T + E +IR K
Sbjct: 511 PHLSRVRSLELDDWPVELRKVMSSIVNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSK 570
Query: 123 YEKKKY 128
YE+K +
Sbjct: 571 YEEKLF 576
>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 8 [Homo sapiens]
Length = 663
Score = 96.7 bits (239), Expect = 4e-20
Identities = 45/126 (35%), Positives = 71/126 (56%), Gaps = 2/126 (1%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIH +LG
Sbjct: 428 SSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHHSLG 487
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQAVEFFIRDK 122
+SRV+S+ LD W E + M +GN A ++E + + T + E +IR K
Sbjct: 488 TRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSK 547
Query: 123 YEKKKY 128
YE+K +
Sbjct: 548 YEEKLF 553
>gi|6806913 centaurin, alpha 1 [Homo sapiens]
Length = 374
Score = 95.9 bits (237), Expect = 7e-20
Identities = 49/117 (41%), Positives = 72/117 (61%), Gaps = 5/117 (4%)
Query: 15 EQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVN 74
E+ + +L +LL+ N CADC A P WAS+ +GVFIC+ C+GIHRN+ +S+VKSV
Sbjct: 4 ERRRAVL-ELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVR 61
Query: 75 LDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAV---EFFIRDKYEKKKY 128
LD W Q++ M GN AR +E+ +P + RP E +IR KYE++++
Sbjct: 62 LDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEF 118
>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 5 [Homo sapiens]
Length = 686
Score = 94.0 bits (232), Expect = 3e-19
Identities = 46/127 (36%), Positives = 73/127 (57%), Gaps = 4/127 (3%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C D E + P+WAS N+GV +CI C+GIHR+LG
Sbjct: 451 SSKSKSQLTSQSEAMALQSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLG 510
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRP---QTDQAVEFFIRD 121
+SRV+S+ LD W E + M +GN A ++E + + +P T + E +IR
Sbjct: 511 TRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGS-SQGQTKPSVKSTREEKERWIRS 569
Query: 122 KYEKKKY 128
KYE+K +
Sbjct: 570 KYEEKLF 576
>gi|8923763 centaurin-alpha 2 protein [Homo sapiens]
Length = 381
Score = 93.2 bits (230), Expect = 5e-19
Identities = 49/119 (41%), Positives = 73/119 (61%), Gaps = 6/119 (5%)
Query: 15 EQHQLILSKLLREED--NKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72
E+++ L +LLR D N +CADC A P WAS+ +G+FIC+ C G+HRN ISRVKS
Sbjct: 5 ERNKKRLLELLRAPDTGNAHCADCGAADPDWASYKLGIFICLNCCGVHRNF-PDISRVKS 63
Query: 73 VNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAV---EFFIRDKYEKKKY 128
V LD W ++ M GN + + +EA +P + PQ + + E +IR KYE++++
Sbjct: 64 VRLDFWDDSIVEFMIHNGNLRVKAKFEARVPAFYYIPQANDCLVLKEQWIRAKYERREF 122
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 91.7 bits (226), Expect = 1e-18
Identities = 51/152 (33%), Positives = 84/152 (55%), Gaps = 13/152 (8%)
Query: 1 MATRSCREKAQ---KLNEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRC 56
+A+ C E ++ + + Q + + + +R + N C DC A P WAS N+G ICI C
Sbjct: 910 LASLQCCESSKVKLRTDSQSEAVAIQAIRNAKGNSICVDCGAPNPTWASLNLGALICIEC 969
Query: 57 AGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQA 114
+GIHRNLG H+SRV+S++LD W E + +GN A ++E++ + R + +
Sbjct: 970 SGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESDTRGRAKPSRDSSREE 1029
Query: 115 VEFFIRDKYEKKKYYDKNAIAITNISSSDAPL 146
E +IR KYE+ + + +S+S+ PL
Sbjct: 1030 RESWIRAKYEQ-------LLFLAPLSTSEEPL 1054
>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
Length = 836
Score = 91.7 bits (226), Expect = 1e-18
Identities = 51/152 (33%), Positives = 84/152 (55%), Gaps = 13/152 (8%)
Query: 1 MATRSCREKAQ---KLNEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRC 56
+A+ C E ++ + + Q + + + +R + N C DC A P WAS N+G ICI C
Sbjct: 554 LASLQCCESSKVKLRTDSQSEAVAIQAIRNAKGNSICVDCGAPNPTWASLNLGALICIEC 613
Query: 57 AGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQA 114
+GIHRNLG H+SRV+S++LD W E + +GN A ++E++ + R + +
Sbjct: 614 SGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESDTRGRAKPSRDSSREE 673
Query: 115 VEFFIRDKYEKKKYYDKNAIAITNISSSDAPL 146
E +IR KYE+ + + +S+S+ PL
Sbjct: 674 RESWIRAKYEQ-------LLFLAPLSTSEEPL 698
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 91.3 bits (225), Expect = 2e-18
Identities = 44/116 (37%), Positives = 70/116 (60%), Gaps = 4/116 (3%)
Query: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
+++++ + N C DC P WAS N+GV +CI+C+GIHR+LGVH S+V+S+ LD W
Sbjct: 407 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWE 466
Query: 80 AEQIQCMQDMGNTKARLLYEANLPE-NFRRPQ---TDQAVEFFIRDKYEKKKYYDK 131
E ++ M ++GN +YEA + ++P + Q E +I KY +KK+ K
Sbjct: 467 PELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTK 522
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 87.8 bits (216), Expect = 2e-17
Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 3/140 (2%)
Query: 13 LNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72
L + + I+ + R N C DC + P W S N+G+ CI C+GIHR +GVHISR++S
Sbjct: 434 LEDLTKAIIEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQS 493
Query: 73 VNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYDKN 132
+ LD+ ++ +++GN + EANLP P+ + + +R +Y KY D +
Sbjct: 494 LELDKLGTSELLLAKNVGNNSFNDIMEANLPS--PSPKPTPSSDMTVRKEYITAKYVD-H 550
Query: 133 AIAITNISSSDAPLQPLVSS 152
+ S+S A L L+ +
Sbjct: 551 RFSRKTCSTSSAKLNELLEA 570
>gi|31543983 ADP-ribosylation factor GTPase activating protein 2
[Homo sapiens]
Length = 521
Score = 82.4 bits (202), Expect = 8e-16
Identities = 43/102 (42%), Positives = 56/102 (54%), Gaps = 9/102 (8%)
Query: 18 QLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLD- 76
Q + +L NK C DC AK P WAS GVF+CI C+G+HR+LGVH+S ++S LD
Sbjct: 11 QTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDS 70
Query: 77 QWTAEQIQCMQDMGNTKARLLY--------EANLPENFRRPQ 110
W Q++CMQ GN A + +AN N R Q
Sbjct: 71 NWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQ 112
>gi|214829714 ADP-ribosylation factor GTPase activating protein 3
isoform 2 [Homo sapiens]
Length = 472
Score = 80.9 bits (198), Expect = 2e-15
Identities = 43/92 (46%), Positives = 56/92 (60%), Gaps = 2/92 (2%)
Query: 14 NEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72
++Q L + K LR NK C DC AK P WAS GVF+CI C+G HR+LGVH+S ++S
Sbjct: 5 SKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRS 64
Query: 73 VNLD-QWTAEQIQCMQDMGNTKARLLYEANLP 103
LD W+ Q++CMQ GN A L +P
Sbjct: 65 TELDSNWSWFQLRCMQVGGNASALWLDSCVVP 96
>gi|214829673 ADP-ribosylation factor GTPase activating protein 3
isoform 1 [Homo sapiens]
Length = 516
Score = 80.1 bits (196), Expect = 4e-15
Identities = 41/83 (49%), Positives = 53/83 (63%), Gaps = 2/83 (2%)
Query: 14 NEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72
++Q L + K LR NK C DC AK P WAS GVF+CI C+G HR+LGVH+S ++S
Sbjct: 5 SKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRS 64
Query: 73 VNLD-QWTAEQIQCMQDMGNTKA 94
LD W+ Q++CMQ GN A
Sbjct: 65 TELDSNWSWFQLRCMQVGGNASA 87
>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform b [Homo sapiens]
Length = 961
Score = 79.3 bits (194), Expect = 7e-15
Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 9/123 (7%)
Query: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
I+S++ R N C DC A P W S N+G+ CI C+GIHR LGVH SR++S+ LD
Sbjct: 423 IISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLG 482
Query: 80 AEQIQCMQDMGNTKARLLYEANLP-ENFRRP--------QTDQAVEFFIRDKYEKKKYYD 130
++ +++GN + E LP E+ +P + D +I +Y +KK+ D
Sbjct: 483 TSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHAD 542
Query: 131 KNA 133
A
Sbjct: 543 NAA 545
>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform a [Homo sapiens]
Length = 1006
Score = 79.3 bits (194), Expect = 7e-15
Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 9/123 (7%)
Query: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
I+S++ R N C DC A P W S N+G+ CI C+GIHR LGVH SR++S+ LD
Sbjct: 423 IISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLG 482
Query: 80 AEQIQCMQDMGNTKARLLYEANLP-ENFRRP--------QTDQAVEFFIRDKYEKKKYYD 130
++ +++GN + E LP E+ +P + D +I +Y +KK+ D
Sbjct: 483 TSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHAD 542
Query: 131 KNA 133
A
Sbjct: 543 NAA 545
>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform b [Homo sapiens]
Length = 894
Score = 77.4 bits (189), Expect = 3e-14
Identities = 39/113 (34%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Query: 18 QLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQ 77
+L+++++ N C DC A P W S N+GV CI+C+G+HR LGV SR++S+ LD
Sbjct: 417 KLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDL 476
Query: 78 WTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYD 130
++ +MGNT + EA LP + P+ + R Y KY +
Sbjct: 477 LGPSELLLALNMGNTSFNEVMEAQLPSH-GGPKPSAESDMGTRRDYIMAKYVE 528
>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform a [Homo sapiens]
Length = 903
Score = 77.4 bits (189), Expect = 3e-14
Identities = 39/113 (34%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Query: 18 QLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQ 77
+L+++++ N C DC A P W S N+GV CI+C+G+HR LGV SR++S+ LD
Sbjct: 426 KLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDL 485
Query: 78 WTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYD 130
++ +MGNT + EA LP + P+ + R Y KY +
Sbjct: 486 LGPSELLLALNMGNTSFNEVMEAQLPSH-GGPKPSAESDMGTRRDYIMAKYVE 537
>gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform a [Homo sapiens]
Length = 1205
Score = 75.1 bits (183), Expect = 1e-13
Identities = 39/103 (37%), Positives = 56/103 (54%), Gaps = 4/103 (3%)
Query: 30 NKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQ--WTAEQIQCMQ 87
N++CADC A P WAS N+ V IC RCAG HR LG +S+V+S+ +D+ WT I+
Sbjct: 302 NRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFL 361
Query: 88 DMGNTKARLLYEANLP--ENFRRPQTDQAVEFFIRDKYEKKKY 128
+GN + AN+P E + + + KY + KY
Sbjct: 362 QLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKY 404
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,420,806
Number of Sequences: 37866
Number of extensions: 1153601
Number of successful extensions: 15272
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 302
Number of HSP's successfully gapped in prelim test: 599
Number of HSP's that attempted gapping in prelim test: 9339
Number of HSP's gapped (non-prelim): 4152
length of query: 467
length of database: 18,247,518
effective HSP length: 106
effective length of query: 361
effective length of database: 14,233,722
effective search space: 5138373642
effective search space used: 5138373642
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.