BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo sapiens] (1724 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo... 3455 0.0 gi|194306644 BCSC-1 isoform 1 [Homo sapiens] 161 4e-39 gi|38195080 BCSC-1 isoform 1 [Homo sapiens] 161 4e-39 gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo... 114 6e-25 gi|38195082 BCSC-1 isoform 2 [Homo sapiens] 114 6e-25 gi|210147462 von Willebrand factor A domain containing 5B1 [Homo... 105 3e-22 gi|110825963 poly (ADP-ribose) polymerase family, member 2 isofo... 103 1e-21 gi|110825961 poly (ADP-ribose) polymerase family, member 2 isofo... 103 1e-21 gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo... 79 4e-14 gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo... 79 4e-14 gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens] 70 2e-11 gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [... 52 7e-06 gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 48 9e-05 gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 47 1e-04 gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 47 2e-04 gi|222352129 von Willebrand factor A domain containing 5B2 [Homo... 47 2e-04 gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens] 44 0.002 gi|228008410 BEN domain containing 4 isoform b [Homo sapiens] 42 0.005 gi|148762950 BEN domain containing 4 isoform a [Homo sapiens] 42 0.005 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 42 0.007 gi|118498362 kinectin 1 isoform b [Homo sapiens] 41 0.009 gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens] 40 0.015 gi|55750053 atrophin-1 [Homo sapiens] 40 0.015 gi|55750041 atrophin-1 [Homo sapiens] 40 0.015 gi|150417989 cyclin K isoform 1 [Homo sapiens] 40 0.020 gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 40 0.026 gi|18959210 WIRE protein [Homo sapiens] 39 0.057 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 38 0.097 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 38 0.097 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 38 0.097 >gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo sapiens] Length = 1724 Score = 3455 bits (8959), Expect = 0.0 Identities = 1724/1724 (100%), Positives = 1724/1724 (100%) Query: 1 MVMGIFANCIFCLKVKYLPQQQKKKLQTDIKENGGKFSFSLNPQCTHIILDNADVLSQYQ 60 MVMGIFANCIFCLKVKYLPQQQKKKLQTDIKENGGKFSFSLNPQCTHIILDNADVLSQYQ Sbjct: 1 MVMGIFANCIFCLKVKYLPQQQKKKLQTDIKENGGKFSFSLNPQCTHIILDNADVLSQYQ 60 Query: 61 LNSIQKNHVHIANPDFIWKSIREKRLLDVKNYDPYKPLDITPPPDQKASSSEVKTEGLCP 120 LNSIQKNHVHIANPDFIWKSIREKRLLDVKNYDPYKPLDITPPPDQKASSSEVKTEGLCP Sbjct: 61 LNSIQKNHVHIANPDFIWKSIREKRLLDVKNYDPYKPLDITPPPDQKASSSEVKTEGLCP 120 Query: 121 DSATEEEDTVELTEFGMQNVEIPHLPQDFEVAKYNTLEKVGMEGGQEAVVVELQCSRDSR 180 DSATEEEDTVELTEFGMQNVEIPHLPQDFEVAKYNTLEKVGMEGGQEAVVVELQCSRDSR Sbjct: 121 DSATEEEDTVELTEFGMQNVEIPHLPQDFEVAKYNTLEKVGMEGGQEAVVVELQCSRDSR 180 Query: 181 DCPFLISSHFLLDDGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLREHFTPEATQL 240 DCPFLISSHFLLDDGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLREHFTPEATQL Sbjct: 181 DCPFLISSHFLLDDGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLREHFTPEATQL 240 Query: 241 ASEQLQALLLEEVMNSSTLSQEVSDLVEMIWAEALGHLEHMLLKPVNRISLNDVSKAEGI 300 ASEQLQALLLEEVMNSSTLSQEVSDLVEMIWAEALGHLEHMLLKPVNRISLNDVSKAEGI Sbjct: 241 ASEQLQALLLEEVMNSSTLSQEVSDLVEMIWAEALGHLEHMLLKPVNRISLNDVSKAEGI 300 Query: 301 LLLVKAALKNGETAEQLQKMMTEFYRLIPHKGTMPKEVNLGLLAKKADLCQLIRDMVNVC 360 LLLVKAALKNGETAEQLQKMMTEFYRLIPHKGTMPKEVNLGLLAKKADLCQLIRDMVNVC Sbjct: 301 LLLVKAALKNGETAEQLQKMMTEFYRLIPHKGTMPKEVNLGLLAKKADLCQLIRDMVNVC 360 Query: 361 ETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQIFRVGRV 420 ETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQIFRVGRV Sbjct: 361 ETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQIFRVGRV 420 Query: 421 NETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSD 480 NETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSD Sbjct: 421 NETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSD 480 Query: 481 SLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTASVT 540 SLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTASVT Sbjct: 481 SLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTASVT 540 Query: 541 TDFEDDEFVVYKTNQVKMKYIIKFSMPGDQIKDFHPSDHTELEEYRPEFSNFSKVEDYQL 600 TDFEDDEFVVYKTNQVKMKYIIKFSMPGDQIKDFHPSDHTELEEYRPEFSNFSKVEDYQL Sbjct: 541 TDFEDDEFVVYKTNQVKMKYIIKFSMPGDQIKDFHPSDHTELEEYRPEFSNFSKVEDYQL 600 Query: 601 PDAKTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFP 660 PDAKTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFP Sbjct: 601 PDAKTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFP 660 Query: 661 LDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQDAPDVFTVSVGN 720 LDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQDAPDVFTVSVGN Sbjct: 661 LDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQDAPDVFTVSVGN 720 Query: 721 LPPKAKVLIKITYITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTK 780 LPPKAKVLIKITYITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTK Sbjct: 721 LPPKAKVLIKITYITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTK 780 Query: 781 QSFSLTMSIEMPYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYL 840 QSFSLTMSIEMPYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYL Sbjct: 781 QSFSLTMSIEMPYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYL 840 Query: 841 PRMWVEKHPEKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIAL 900 PRMWVEKHPEKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIAL Sbjct: 841 PRMWVEKHPEKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIAL 900 Query: 901 HALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTMAAEFIMSATPTMGNTDFWKTLRYL 960 HALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTMAAEFIMSATPTMGNTDFWKTLRYL Sbjct: 901 HALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTMAAEFIMSATPTMGNTDFWKTLRYL 960 Query: 961 SLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCG 1020 SLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCG Sbjct: 961 SLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCG 1020 Query: 1021 AGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFL 1080 AGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFL Sbjct: 1021 AGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFL 1080 Query: 1081 NDRLLVYGFIPHCTQATLCALIQEKEFRTMVSTTELQKTTGTMIHKLAARALIRDYEDGI 1140 NDRLLVYGFIPHCTQATLCALIQEKEFRTMVSTTELQKTTGTMIHKLAARALIRDYEDGI Sbjct: 1081 NDRLLVYGFIPHCTQATLCALIQEKEFRTMVSTTELQKTTGTMIHKLAARALIRDYEDGI 1140 Query: 1141 LHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDENESPFPDIPKVSELIAK 1200 LHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDENESPFPDIPKVSELIAK Sbjct: 1141 LHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDENESPFPDIPKVSELIAK 1200 Query: 1201 EDVDFLPYMSWQGEPQEAVRNQSLLASSEWPELRLSKRKHRKIPFSKRKMELSQPEVSED 1260 EDVDFLPYMSWQGEPQEAVRNQSLLASSEWPELRLSKRKHRKIPFSKRKMELSQPEVSED Sbjct: 1201 EDVDFLPYMSWQGEPQEAVRNQSLLASSEWPELRLSKRKHRKIPFSKRKMELSQPEVSED 1260 Query: 1261 FEEDGLGVLPAFTSNLERGGVEKLLDLSWTESCKPTATEPLFKKVSPWETSTSSFFPILA 1320 FEEDGLGVLPAFTSNLERGGVEKLLDLSWTESCKPTATEPLFKKVSPWETSTSSFFPILA Sbjct: 1261 FEEDGLGVLPAFTSNLERGGVEKLLDLSWTESCKPTATEPLFKKVSPWETSTSSFFPILA 1320 Query: 1321 PAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIPQS 1380 PAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIPQS Sbjct: 1321 PAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIPQS 1380 Query: 1381 ASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQLHFS 1440 ASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQLHFS Sbjct: 1381 ASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQLHFS 1440 Query: 1441 LPTDPDPIRGFGSYHPSASSPFHFQPSAASLTANLRLPMASALPEALCSQSRTTPVDLCL 1500 LPTDPDPIRGFGSYHPSASSPFHFQPSAASLTANLRLPMASALPEALCSQSRTTPVDLCL Sbjct: 1441 LPTDPDPIRGFGSYHPSASSPFHFQPSAASLTANLRLPMASALPEALCSQSRTTPVDLCL 1500 Query: 1501 LEESVGSLEGSRCPVFAFQSSDTESDELSEVLQDSCFLQIKCDTKDDSILCFLEVKEEDE 1560 LEESVGSLEGSRCPVFAFQSSDTESDELSEVLQDSCFLQIKCDTKDDSILCFLEVKEEDE Sbjct: 1501 LEESVGSLEGSRCPVFAFQSSDTESDELSEVLQDSCFLQIKCDTKDDSILCFLEVKEEDE 1560 Query: 1561 IVCIQHWQDAVPWTELLSLQTEDGFWKLTPELGLILNLNTNGLHSFLKQKGIQSLGVKGR 1620 IVCIQHWQDAVPWTELLSLQTEDGFWKLTPELGLILNLNTNGLHSFLKQKGIQSLGVKGR Sbjct: 1561 IVCIQHWQDAVPWTELLSLQTEDGFWKLTPELGLILNLNTNGLHSFLKQKGIQSLGVKGR 1620 Query: 1621 ECLLDLIATMLVLQFIRTRLEKEGIVFKSLMKMDDASISRNIPWAFEAIKQASEWVRRTE 1680 ECLLDLIATMLVLQFIRTRLEKEGIVFKSLMKMDDASISRNIPWAFEAIKQASEWVRRTE Sbjct: 1621 ECLLDLIATMLVLQFIRTRLEKEGIVFKSLMKMDDASISRNIPWAFEAIKQASEWVRRTE 1680 Query: 1681 GQYPSICPRLELGNDWDSATKQLLGLQPISTVSPLHRVLHYSQG 1724 GQYPSICPRLELGNDWDSATKQLLGLQPISTVSPLHRVLHYSQG Sbjct: 1681 GQYPSICPRLELGNDWDSATKQLLGLQPISTVSPLHRVLHYSQG 1724 >gi|194306644 BCSC-1 isoform 1 [Homo sapiens] Length = 786 Score = 161 bits (408), Expect = 4e-39 Identities = 156/596 (26%), Positives = 270/596 (45%), Gaps = 53/596 (8%) Query: 621 VPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIV 680 VPL+ + + I + VA V Y N+ VP+EA ++FP+D+ +AV FEA ++GK IV Sbjct: 15 VPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIV 74 Query: 681 GEIKEKEEAQQEYLEAVTQGHGAYLMSQDAP--DVFTVSVGNLPPKAKVLIKITYITELS 738 E+++K +A+ Y +A++QGH A+L+ D+ DVF+ +VGNL P +K + + Y+ EL Sbjct: 75 AELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELP 134 Query: 739 ILGTVGV-FFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTMSIEMPYVIEF 797 + + F +PA + P Q +++ V+ + + S+ +I+ + IE Sbjct: 135 LEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEK 194 Query: 798 I-----FSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEK-HPEK 851 + S T L + +T A +S G D L I + + P + +E P Sbjct: 195 VQSNCPLSPTEYLGEDKT--SAQVSLAAGHKFDRD-VELLIYYNEVHTPSVVLEMGMPNM 251 Query: 852 E------SEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQ---------AK 896 + + M+ F P++ D P E I +D S SM+ Q AK Sbjct: 252 KPGHLMGDPSAMVSFYPNIPEDQPSNTC-GEFIFLMDRSGSMQSPMSSQDTSQLRIQAAK 310 Query: 897 QIALHALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTM--AAEFIMSATPTMGNTDFW 954 + + L + NI FG+ Y+ F T TM A + +G T+ Sbjct: 311 ETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEIL 370 Query: 955 KTLR--YLSLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHV 1012 L+ Y P + + +DG + D ++ V+ +R R F+ GIG + + Sbjct: 371 APLQNIYRGPSIPGH-PLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSL 429 Query: 1013 LRILSQCGAGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAP 1072 ++ +++ G E+ K + + + + R P VS+ W L P + + +P Sbjct: 430 IKGIARASGGTSEFITGKDR--MQSKALRTLKRSLQPVVEDVSLSW-HLPPGLSAKMLSP 486 Query: 1073 AQVPSLFLNDRLLVY----GFIPHC-TQATLCA--LIQEKEFRTMVS-TTELQKTTGTMI 1124 Q +F RL+ Y G +P T +C +Q K F V+ + + I Sbjct: 487 EQT-VIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTI 545 Query: 1125 HKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEK 1180 H+LAA++L++ + G+ ET KK L LS E+ +I+ FT+F+A+ K Sbjct: 546 HRLAAKSLLQTKDMGL---RETPASDKKDAL-----NLSLESGVISSFTAFIAINK 593 >gi|38195080 BCSC-1 isoform 1 [Homo sapiens] Length = 786 Score = 161 bits (408), Expect = 4e-39 Identities = 156/596 (26%), Positives = 270/596 (45%), Gaps = 53/596 (8%) Query: 621 VPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIV 680 VPL+ + + I + VA V Y N+ VP+EA ++FP+D+ +AV FEA ++GK IV Sbjct: 15 VPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIV 74 Query: 681 GEIKEKEEAQQEYLEAVTQGHGAYLMSQDAP--DVFTVSVGNLPPKAKVLIKITYITELS 738 E+++K +A+ Y +A++QGH A+L+ D+ DVF+ +VGNL P +K + + Y+ EL Sbjct: 75 AELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELP 134 Query: 739 ILGTVGV-FFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTMSIEMPYVIEF 797 + + F +PA + P Q +++ V+ + + S+ +I+ + IE Sbjct: 135 LEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEK 194 Query: 798 I-----FSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEK-HPEK 851 + S T L + +T A +S G D L I + + P + +E P Sbjct: 195 VQSNCPLSPTEYLGEDKT--SAQVSLAAGHKFDRD-VELLIYYNEVHTPSVVLEMGMPNM 251 Query: 852 E------SEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQ---------AK 896 + + M+ F P++ D P E I +D S SM+ Q AK Sbjct: 252 KPGHLMGDPSAMVSFYPNIPEDQPSNTC-GEFIFLMDRSGSMQSPMSSQDTSQLRIQAAK 310 Query: 897 QIALHALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTM--AAEFIMSATPTMGNTDFW 954 + + L + NI FG+ Y+ F T TM A + +G T+ Sbjct: 311 ETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEIL 370 Query: 955 KTLR--YLSLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHV 1012 L+ Y P + + +DG + D ++ V+ +R R F+ GIG + + Sbjct: 371 APLQNIYRGPSIPGH-PLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSL 429 Query: 1013 LRILSQCGAGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAP 1072 ++ +++ G E+ K + + + + R P VS+ W L P + + +P Sbjct: 430 IKGIARASGGTSEFITGKDR--MQSKALRTLKRSLQPVVEDVSLSW-HLPPGLSAKMLSP 486 Query: 1073 AQVPSLFLNDRLLVY----GFIPHC-TQATLCA--LIQEKEFRTMVS-TTELQKTTGTMI 1124 Q +F RL+ Y G +P T +C +Q K F V+ + + I Sbjct: 487 EQT-VIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTI 545 Query: 1125 HKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEK 1180 H+LAA++L++ + G+ ET KK L LS E+ +I+ FT+F+A+ K Sbjct: 546 HRLAAKSLLQTKDMGL---RETPASDKKDAL-----NLSLESGVISSFTAFIAINK 593 >gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo sapiens] Length = 1014 Score = 114 bits (286), Expect = 6e-25 Identities = 150/624 (24%), Positives = 258/624 (41%), Gaps = 103/624 (16%) Query: 21 QQKKKLQTDIKENGGKFSFSLNPQCTHIILDNADVLSQYQLNSIQKNHVHIANPDFIW-- 78 + K +++ I++ GGK + + N I ++ +++ ++ + + DF+ Sbjct: 403 RNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDV 462 Query: 79 ----KSIREKRLLDVKNYDPY------KPLDITPPPDQ------KASSSEVKTEGLCPDS 122 KS++E L + + P+ +P+++ P + K S +VK EG+ Sbjct: 463 SASTKSLQELFLAHILS--PWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGI---- 516 Query: 123 ATEEEDTVELTEFGMQNVEIPHLPQDFEVAKYNTLEKVGMEGGQEAVVVE---------- 172 + E ++LT G V+ P + LEK G +V+ Sbjct: 517 -NKSEKRMKLTLKGGAAVD----PDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYK 571 Query: 173 LQCSRDSRDCPFLISSHFLLDDGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLR-- 230 LQ D ++ + I + + + + EDA E+F EE + + Sbjct: 572 LQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNF 631 Query: 231 ----EHFTP-EATQLASEQLQALLLEEVMNSSTLSQEVSDLVEMIW-----AEALGHLEH 280 + F P E E+ L S L + V DL++MI+ +A+ E Sbjct: 632 TKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEI 691 Query: 281 MLLK-PVNRISLNDVSKAEGILLLVKAALKNGETAEQLQKMMTEFYRLIPHKGTMPKEVN 339 L K P+ ++S + A IL V+ A+ G + Q+ + FY LIPH M K Sbjct: 692 DLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPP- 750 Query: 340 LGLLAKKADLCQLIRDMV-NVCETNLS----------KPNPPSLAKYRALRCKIEHVEQN 388 L AD Q +M+ N+ + ++ P Y L+ I+ V+++ Sbjct: 751 ---LLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRD 807 Query: 389 TEEFLRVRKEVLQNH---HSKSPVDVLQIFRVGRVNETTEF--LSKLGNVRPLLHGSPVQ 443 +EE +RK V H H+ ++V+ IF++ R E + +L N R L HGS Sbjct: 808 SEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTT 867 Query: 444 NIVGILCRGL-LLPKVVEDRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLI 502 N GIL +GL + P G G GIYF+D +S S Y H + D L+L+ Sbjct: 868 NFAGILSQGLRIAPPEAPVTGYM------FGKGIYFADMVSKSANYCHTSQGDPIGLILL 921 Query: 503 CDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQT-----ASVTTDFED------------ 545 +VALG +L +++ P G SV G+ +T A+++ D D Sbjct: 922 GEVALGNMYELKHAS-HISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVN 980 Query: 546 ------DEFVVYKTNQVKMKYIIK 563 +E++VY QV +KY++K Sbjct: 981 DTSLLYNEYIVYDIAQVNLKYLLK 1004 >gi|38195082 BCSC-1 isoform 2 [Homo sapiens] Length = 415 Score = 114 bits (286), Expect = 6e-25 Identities = 107/406 (26%), Positives = 183/406 (45%), Gaps = 33/406 (8%) Query: 621 VPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIV 680 VPL+ + + I + VA V Y N+ VP+EA ++FP+D+ +AV FEA ++GK IV Sbjct: 15 VPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIV 74 Query: 681 GEIKEKEEAQQEYLEAVTQGHGAYLMSQDAP--DVFTVSVGNLPPKAKVLIKITYITELS 738 E+++K +A+ Y +A++QGH A+L+ D+ DVF+ +VGNL P +K + + Y+ EL Sbjct: 75 AELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELP 134 Query: 739 ILGTVGV-FFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTMSIEMPYVIEF 797 + + F +PA + P Q +++ V+ + + S+ +I+ + IE Sbjct: 135 LEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEK 194 Query: 798 I-----FSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEK-HPEK 851 + S T L + +T A +S G D L I + + P + +E P Sbjct: 195 VQSNCPLSPTEYLGEDKT--SAQVSLAAGHKFDRD-VELLIYYNEVHTPSVVLEMGMPNM 251 Query: 852 E------SEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQ---------AK 896 + + M+ F P++ D P E I +D S SM+ Q AK Sbjct: 252 KPGHLMGDPSAMVSFYPNIPEDQPSNTC-GEFIFLMDRSGSMQSPMSSQDTSQLRIQAAK 310 Query: 897 QIALHALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTM--AAEFIMSATPTMGNTDFW 954 + + L + NI FG+ Y+ F T TM A + +G T+ Sbjct: 311 ETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEIL 370 Query: 955 KTLR--YLSLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTR 998 L+ Y P + + +DG + D ++ V+ +R R Sbjct: 371 APLQNIYRGPSIPGH-PLQLFVFTDGEVTDTFSVIKEVRINRQKHR 415 >gi|210147462 von Willebrand factor A domain containing 5B1 [Homo sapiens] Length = 1215 Score = 105 bits (263), Expect = 3e-22 Identities = 121/543 (22%), Positives = 216/543 (39%), Gaps = 100/543 (18%) Query: 644 TYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEA------V 697 TY N P + +++PLD+ V GFEA I + + +IK+K + + + +A Sbjct: 36 TYGNLEAQPFQGLFVYPLDECTTVIGFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPT 95 Query: 698 TQGH---------------GAYLMSQDAPDV-FTVSVGNLPPKAKVLIKITYITELSILG 741 G+ G + +D + F ++G + P V I I+ +EL L Sbjct: 96 VTGNILQDGVSIAPHSCTPGKVTLDEDLERILFVANLGTIAPMENVTIFISTSSELPTLP 155 Query: 742 TVGV-FFMPATVAPW------QQDKALNENLQD------------TVEKICIKEIGTKQ- 781 + V +PA AP + N+ Q + K+C+ + + Sbjct: 156 SGAVRVLLPAVCAPTVPQFCTKSTGTSNQQAQGKDRHCFGAWAPGSWNKLCLATLLNTEV 215 Query: 782 ------SFSLTMSIEMPYVIEFIFSDTHELKQKRT----DCKAVISTMEGSSLDSSGFSL 831 F+ + I P ++ + S THE++ K++I T+ + Sbjct: 216 SNPMEYEFNFQLEIRGPCLLAGVESPTHEIRADAAPSARSAKSIIITLANKHTFDRPVEI 275 Query: 832 HIGLSAAYLPRMWVEK--------------------------HPEKESE----------- 854 I S ++P + +EK E+++E Sbjct: 276 LIHPSEPHMPHVLIEKGDMTLGEFDQHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDIP 335 Query: 855 ---ACMLVFQPDLDVDLPDLA-SESEVIICLDCSSSMEGVTFLQAKQIALHALSLVGEKQ 910 ML F PDL P L + E I +D SSSM G++ + K L AL + Sbjct: 336 HHSVIMLNFCPDLQSVQPCLRKAHGEFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPAC 395 Query: 911 KVNIIQFGTGYKELFSYPKHITSNT--MAAEFIMSATPTMGNTDFWKTLRYLSLLYPARG 968 NII FG+ +K LF + + ++ MA + I MG T+ L+++ RG Sbjct: 396 LFNIIGFGSTFKSLFPSSQTYSEDSLAMACDDIQRMKADMGGTNILSPLKWVIRQPVHRG 455 Query: 969 -SRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCGAGVFEYF 1027 R + +++DG + + L+LV+ TR ++ GIG +++ L+ G E Sbjct: 456 HPRLLFVITDGAVNNTGKVLELVRNHAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELL 515 Query: 1028 NAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFLNDRLLVY 1087 + + ++ + + +P V+V+W + P+ E L +P SLF +RL+ Y Sbjct: 516 MEGER--LQPKMVKSLKKAMAPVLSDVTVEW--IFPETTEVLVSPVSASSLFPGERLVGY 571 Query: 1088 GFI 1090 G + Sbjct: 572 GIV 574 Score = 35.0 bits (79), Expect = 0.63 Identities = 28/111 (25%), Positives = 48/111 (43%), Gaps = 9/111 (8%) Query: 1125 HKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDEN 1184 H LAARA+IRD+E E E ++ S + SK ++I+++T+FV V+ Sbjct: 852 HHLAARAIIRDFEQLAEREGEIEQGSNRRYQVS-ALHTSKACNIISKYTAFVPVDVSKSR 910 Query: 1185 ESP----FPDIPKVSELIAKEDVDFLPYMSWQGEPQEAVRNQSLLASSEWP 1231 P +P+ ++ + W+G R Q++L P Sbjct: 911 YLPTVVEYPNSGAALRMLGSRAL----AQQWRGTSSGFGRPQTMLGEDSAP 957 >gi|110825963 poly (ADP-ribose) polymerase family, member 2 isoform 2 [Homo sapiens] Length = 570 Score = 103 bits (258), Expect = 1e-21 Identities = 90/351 (25%), Positives = 148/351 (42%), Gaps = 52/351 (14%) Query: 257 STLSQEVSDLVEMIWAEALGHLEHMLLK--------PVNRISLNDVSKAEGILLLVKAAL 308 S L V +L+++I + +E M+++ P+ ++++ + L ++ + Sbjct: 219 SQLDLRVQELIKLICN--VQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCI 276 Query: 309 KNGETAEQLQKMMTEFYRLIPHK---GTMPKEVNLGLLAKKADLCQLIRDM---VNVCET 362 + G+ L + EFY IPH T P L++K L + + D+ + + +T Sbjct: 277 RAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKT 336 Query: 363 NLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNH---HSKSPVDVLQIFRVGR 419 L P P YR L C + ++ + EF + + + H HS + +L +F V + Sbjct: 337 ELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEK 396 Query: 420 VNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGL-LLPKVVEDRGVQRTDVGNLGSGIYF 478 E F L N L HGS + N VGIL GL + P G G GIYF Sbjct: 397 DGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYM------FGKGIYF 450 Query: 479 SDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTAS 538 +D S S Y T LLL+ +VALG+C +L E + G S G+ + A Sbjct: 451 ADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAP 510 Query: 539 VTTDF--------------------------EDDEFVVYKTNQVKMKYIIK 563 + F +E++VY NQV+M+Y++K Sbjct: 511 SSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLK 561 >gi|110825961 poly (ADP-ribose) polymerase family, member 2 isoform 1 [Homo sapiens] Length = 583 Score = 103 bits (258), Expect = 1e-21 Identities = 90/351 (25%), Positives = 148/351 (42%), Gaps = 52/351 (14%) Query: 257 STLSQEVSDLVEMIWAEALGHLEHMLLK--------PVNRISLNDVSKAEGILLLVKAAL 308 S L V +L+++I + +E M+++ P+ ++++ + L ++ + Sbjct: 232 SQLDLRVQELIKLICN--VQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCI 289 Query: 309 KNGETAEQLQKMMTEFYRLIPHK---GTMPKEVNLGLLAKKADLCQLIRDM---VNVCET 362 + G+ L + EFY IPH T P L++K L + + D+ + + +T Sbjct: 290 RAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKT 349 Query: 363 NLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNH---HSKSPVDVLQIFRVGR 419 L P P YR L C + ++ + EF + + + H HS + +L +F V + Sbjct: 350 ELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEK 409 Query: 420 VNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGL-LLPKVVEDRGVQRTDVGNLGSGIYF 478 E F L N L HGS + N VGIL GL + P G G GIYF Sbjct: 410 DGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYM------FGKGIYF 463 Query: 479 SDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTAS 538 +D S S Y T LLL+ +VALG+C +L E + G S G+ + A Sbjct: 464 ADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAP 523 Query: 539 VTTDF--------------------------EDDEFVVYKTNQVKMKYIIK 563 + F +E++VY NQV+M+Y++K Sbjct: 524 SSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLK 574 >gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform b [Homo sapiens] Length = 533 Score = 79.0 bits (193), Expect = 4e-14 Identities = 88/421 (20%), Positives = 174/421 (41%), Gaps = 75/421 (17%) Query: 209 EDASEYFENYIEELKKQGFLLREHFTPEATQLASEQLQA----------------LLLEE 252 EDA + FE E K + R+HF + ++QA + + Sbjct: 119 EDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTK 178 Query: 253 VMNSSTLSQEVSDLVEMIWAEALGHLEHMLLK------PVNRISLNDVSKAEGILLLVKA 306 + +L L+ I+++ + L+ P+ ++S +++ L ++ Sbjct: 179 RVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEE 238 Query: 307 ALKNG-ETAEQLQKMMTEFYRLIPHK--GTMPKEVNLG-LLAKKADLCQLIRDM------ 356 ALK + + L+++ + FY +IPH + P +N LL K D+ ++ D+ Sbjct: 239 ALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQAL 298 Query: 357 --VNVCETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQI 414 V+ E + + P Y+ L+C+++ ++ E+ ++ + Q + + I Sbjct: 299 QAVSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHI 358 Query: 415 FRVGRVNETTEFL--SKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNL 472 ++V + E F SKLGN + L HG+ + + IL GL +++ G G + Sbjct: 359 WKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGL---RIMPHSG------GRV 409 Query: 473 GSGIYFSDSLSTSIKYSHPGETDGTRL--LLICDVALGKCMDLHEKDFSLTEAPPGYDSV 530 G GIYF+ S S Y + + + + +VALG+ ++ + SL PPG+DSV Sbjct: 410 GKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSV 469 Query: 531 HGVSQTASVTTD----------------------------FEDDEFVVYKTNQVKMKYII 562 T T F E+++Y+ +Q +++Y++ Sbjct: 470 IARGHTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLL 529 Query: 563 K 563 + Sbjct: 530 E 530 >gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform a [Homo sapiens] Length = 540 Score = 79.0 bits (193), Expect = 4e-14 Identities = 88/421 (20%), Positives = 174/421 (41%), Gaps = 75/421 (17%) Query: 209 EDASEYFENYIEELKKQGFLLREHFTPEATQLASEQLQA----------------LLLEE 252 EDA + FE E K + R+HF + ++QA + + Sbjct: 126 EDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTK 185 Query: 253 VMNSSTLSQEVSDLVEMIWAEALGHLEHMLLK------PVNRISLNDVSKAEGILLLVKA 306 + +L L+ I+++ + L+ P+ ++S +++ L ++ Sbjct: 186 RVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEE 245 Query: 307 ALKNG-ETAEQLQKMMTEFYRLIPHK--GTMPKEVNLG-LLAKKADLCQLIRDM------ 356 ALK + + L+++ + FY +IPH + P +N LL K D+ ++ D+ Sbjct: 246 ALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQAL 305 Query: 357 --VNVCETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQI 414 V+ E + + P Y+ L+C+++ ++ E+ ++ + Q + + I Sbjct: 306 QAVSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHI 365 Query: 415 FRVGRVNETTEFL--SKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNL 472 ++V + E F SKLGN + L HG+ + + IL GL +++ G G + Sbjct: 366 WKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGL---RIMPHSG------GRV 416 Query: 473 GSGIYFSDSLSTSIKYSHPGETDGTRL--LLICDVALGKCMDLHEKDFSLTEAPPGYDSV 530 G GIYF+ S S Y + + + + +VALG+ ++ + SL PPG+DSV Sbjct: 417 GKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSV 476 Query: 531 HGVSQTASVTTD----------------------------FEDDEFVVYKTNQVKMKYII 562 T T F E+++Y+ +Q +++Y++ Sbjct: 477 IARGHTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLL 536 Query: 563 K 563 + Sbjct: 537 E 537 >gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens] Length = 930 Score = 69.7 bits (169), Expect = 2e-11 Identities = 127/613 (20%), Positives = 237/613 (38%), Gaps = 60/613 (9%) Query: 616 ASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFIN 675 A N + + + + R+ A +V N+++ EA + L KA + F I+ Sbjct: 28 AEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRANTVQEATFQMELPKKAFITNFSMIID 87 Query: 676 GKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQDAPDV--FTVSVGNLPPKAKVLIKITY 733 G G IKEK EAQ +Y AV +G A L+ ++ F VSV ++ P AK+ ++ Y Sbjct: 88 GMTYPGIIKEKAEAQAQYSAAVAKGKSAGLVKATGRNMEQFQVSV-SVAPNAKITFELVY 146 Query: 734 ITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTMSIEM-- 791 E + +GV+ + V P Q K L ++ E I + T+ +F ++ Sbjct: 147 --EELLKRRLGVYELLLKVRPQQLVKHLQMDIH-IFEPQGISFLETESTFMTNQLVDALT 203 Query: 792 ----PYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEK 847 F T +QK + + + ++G+ + + + +S + Sbjct: 204 TWQNKTKAHIRFKPTLSQQQKSPEQQETV--LDGNLI--IRYDVDRAISGGSI------- 252 Query: 848 HPEKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIALHALSLVG 907 + E+ + F P+ +P V+ +D S SM G Q ++ + L + Sbjct: 253 --QIENGYFVHYFAPEGLTTMP-----KNVVFVIDKSGSMSGRKIQQTREALIKILDDLS 305 Query: 908 EKQKVNIIQFGTGYKELF-SYPKHITSNTMAAEFIMSATPTMGNTDFWKT-LRYLSLL-- 963 + + N+I F T + S N A + +G T+ L + LL Sbjct: 306 PRDQFNLIVFSTEATQWRPSLVPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDS 365 Query: 964 ------YPARGSRNILLVSD-----GHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHV 1012 P I+L++D G S+ + + LF G G + Sbjct: 366 SNQEERLPEGSVSLIILLTDGDPTVGETNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAF 425 Query: 1013 LRILSQCGAGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAP 1072 L L+ G+ + S + Q++D + +P +V+ ++ + V E Q Sbjct: 426 LEKLALDNGGLARRIHEDSDSA--LQLQDFYQEVANPLLTAVTFEYP--SNAVEEVTQNN 481 Query: 1073 AQVPSLFLNDRLLVYGFI----PHCTQATLCALI--QEKEFRTMVSTTELQ---KTTGTM 1123 ++ LF ++V G + P AT+ + Q F+T S E + ++ + Sbjct: 482 FRL--LFKGSEMVVAGKLQDRGPDVLTATVSGKLPTQNITFQTESSVAEQEAEFQSPKYI 539 Query: 1124 IHKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDE 1183 H R +L + ++ + +Q L++ + LS S +T TS V + D+ Sbjct: 540 FHNFMERLWAYLTIQQLLEQTVSASDADQQALRNQALNLSLAYSFVTPLTSMVVTKPDDQ 599 Query: 1184 NESPFPDIPKVSE 1196 +S + P E Sbjct: 600 EQSQVAEKPMEGE 612 >gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [Homo sapiens] Length = 890 Score = 51.6 bits (122), Expect = 7e-06 Identities = 127/620 (20%), Positives = 231/620 (37%), Gaps = 69/620 (11%) Query: 610 KAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCG 669 K L + N + + I ++ A +V N++ E + L A + Sbjct: 32 KRSLPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELPKTAFITN 91 Query: 670 FEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQDAP--DVFTVSVGNLPPKAKV 727 F I+G G +KEKE A+++Y +AV+QG A L+ + FTVSV N+ +KV Sbjct: 92 FTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSV-NVAAGSKV 150 Query: 728 LIKITYITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTM 787 ++TY E + G + M V P Q K + D E I + + SF Sbjct: 151 TFELTY--EELLKRHKGKYEMYLKVQPKQLVKHFEIEV-DIFEPQGISMLDAEASFITND 207 Query: 788 SIEMPYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEK 847 + F H + D + T S L+ + Y Sbjct: 208 LLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGD-------FTITYDVNRESPG 260 Query: 848 HPEKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIALHALSLVG 907 + + + + F P LP V +D S SM G Q K+ L L + Sbjct: 261 NVQIVNGYFVHFFAPQ---GLP--VVPKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQ 315 Query: 908 EKQKVNIIQFGTGYKELFSYPKHIT----SNTMAAEFIMSATPTMGNTDFWK-TLRYLSL 962 E+ +N I F ++ ++ +H+ N A + + G T+ LR +S+ Sbjct: 316 EEDYLNFILFS---GDVSTWKEHLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGISM 372 Query: 963 L--------YPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTR--------LFACGIGS 1006 L P R + +++++DG D ++ ++ + + R L+ G G+ Sbjct: 373 LNKAREEHRIPERSTSIVIMLTDG---DANVGESRPEKIQENVRNAIGGKFPLYNLGFGN 429 Query: 1007 TANRHVLRILSQCGAGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVP 1066 N + L ++ G S Q++ + +P V +++ + + Sbjct: 430 NLNYNFLENMALENHGFARRIYEDSDAD--LQLQGFYEEVANPLLTGVEMEYPE--NAIL 485 Query: 1067 EALQAPAQVPSLFLNDRLLVYGFIPHCTQATLCALIQ------EKEFRTMVSTTELQKTT 1120 + Q Q + ++V G + + A ++ + F V E++K Sbjct: 486 DLTQNTYQ--HFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEVDMKEMEKAL 543 Query: 1121 -------GTMIHKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFT 1173 G I +L A I + +L + + +H +K+ L + + LS + +T T Sbjct: 544 QERDYIFGNYIERLWAYLTI----EQLLEKRKNAHGEEKENLTARALDLSLKYHFVTPLT 599 Query: 1174 SFVAVEKRD-ENESPFPDIP 1192 S V + D E+E D P Sbjct: 600 SMVVTKPEDNEDERAIADKP 619 >gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 [Homo sapiens] Length = 1166 Score = 47.8 bits (112), Expect = 9e-05 Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 30/162 (18%) Query: 419 RVNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLGSGIYF 478 R E +E N R L HGSP N + + K ++R G G+GIYF Sbjct: 1012 RRKEVSEENHNHANERMLFHGSPFVNAI--------IHKGFDERHAYIG--GMFGAGIYF 1061 Query: 479 SDSLSTSIKYSHPGETDGT--------------RLLLICDVALGKCMDLHEKDFSLTEAP 524 +++ S S +Y + G GT R LL C V LGK L + +P Sbjct: 1062 AENSSKSNQYVY-GIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSF-LQFSAMKMAHSP 1119 Query: 525 PGYDSVHGVSQTASVTTDFEDDEFVVYKTNQVKMKYIIKFSM 566 PG+ SV G + E+V+Y+ Q +Y+I + + Sbjct: 1120 PGHHSVTGRPSVNGLAL----AEYVIYRGEQAYPEYLITYQI 1157 >gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] Length = 1970 Score = 47.4 bits (111), Expect = 1e-04 Identities = 54/195 (27%), Positives = 76/195 (38%), Gaps = 32/195 (16%) Query: 1305 VSPWETSTSSFFPILAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQF 1364 ++PW + + +P+VGS + P A SP++ S DAS F Sbjct: 1517 MTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAAS-------------------DASGF 1557 Query: 1365 SQGPVPGTCADWIPQSASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPL---QHPGGFT 1421 S PG W P P P PSSPY S S + ++P + PGG+T Sbjct: 1558 S----PGYSPAWSP----TPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYT 1609 Query: 1422 TR-PSAGTFPELDSPQLHFSLPTDPDPIRGFGSYHPSASSPFHFQPSAASLTANLRLPMA 1480 + PS SP PT P+ SY P++ S PS S T+ P + Sbjct: 1610 PQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPS-YSPTSPSYSPTS 1668 Query: 1481 SALPEALCSQSRTTP 1495 + S S T+P Sbjct: 1669 PSYSPTSPSYSPTSP 1683 >gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase [Homo sapiens] Length = 1327 Score = 47.0 bits (110), Expect = 2e-04 Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 30/162 (18%) Query: 419 RVNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLGSGIYF 478 R E +E N R L HGSP N + + K ++R G G+GIYF Sbjct: 1165 RQKEVSEENHNHHNERMLFHGSPFINAI--------IHKGFDERHAYIG--GMFGAGIYF 1214 Query: 479 SDSLSTSIKYSHPGETDGT--------------RLLLICDVALGKCMDLHEKDFSLTEAP 524 +++ S S +Y + G GT R +L C V LGK L + AP Sbjct: 1215 AENSSKSNQYVY-GIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSF-LQFSTMKMAHAP 1272 Query: 525 PGYDSVHGVSQTASVTTDFEDDEFVVYKTNQVKMKYIIKFSM 566 PG+ SV G + E+V+Y+ Q +Y+I + + Sbjct: 1273 PGHHSVIGRPSVNGLAY----AEYVIYRGEQAYPEYLITYQI 1310 Score = 33.5 bits (75), Expect = 1.8 Identities = 36/133 (27%), Positives = 52/133 (39%), Gaps = 13/133 (9%) Query: 1295 PTATEPLFKKVSPWETSTSSFFPILAPAVGSYLP-------PTARAHSPASL---SFASY 1344 P + L +P + S P +P G LP P R SP + S S Sbjct: 33 PPLSPGLAPGTTPASPTASGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDGTSCCST 92 Query: 1345 RQVASFGSAAP--PRQFDASQFSQGPVP-GTCADWIPQSASCPTGPPQNPPSSPYCGIVF 1401 +AAP P +S P P G+ ++ P S+S PT + PSSP + Sbjct: 93 TSTICTVAAAPVVPAVSTSSAAGVAPNPAGSGSNNSPSSSSSPTSSSSSSPSSPGSSLAE 152 Query: 1402 SGSSLSSAQSAPL 1414 S + + +APL Sbjct: 153 SPEAAGVSSTAPL 165 >gi|222352129 von Willebrand factor A domain containing 5B2 [Homo sapiens] Length = 1242 Score = 46.6 bits (109), Expect = 2e-04 Identities = 58/240 (24%), Positives = 102/240 (42%), Gaps = 26/240 (10%) Query: 858 LVFQPDLDVDLPDLASES-EVIICLDCSSSMEGVTFLQAKQIALHALSLVGEKQKVNIIQ 916 L F PDL L + + E++ LD SS + K + A+ + + +N+ Sbjct: 335 LSFCPDLSSKPGHLGTATRELLFLLDSSS-------VAHKDAIVLAVKSLPPQTLINLAV 387 Query: 917 FGTGYKELFSYPKHITSNTMAAEFIMSATPTM----GNTDF-----WKTLRYLSLLYPAR 967 FGT + LF P+ + A + I + T+ G D W + YP + Sbjct: 388 FGTLVQPLF--PESRPCSDDAVQLICESIETLQVPSGPPDVLAALDWAVGQPQHRAYPRQ 445 Query: 968 GSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCGAGVFEYF 1027 +L + TL+L++ R R F+ G+G T ++ +L+ LS G + + Sbjct: 446 --LFLLTAASPMAATTHRTLELMRWHRGTARCFSFGLGPTCHQ-LLQGLSALSRG--QAY 500 Query: 1028 NAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFLNDRLLVY 1087 + + + + + P+ +SV W PD EAL P ++P+L+ D+LL Y Sbjct: 501 FLRPGQRLQPMLVQALRKALEPALSDISVDW--FVPDTVEALLTPREIPALYPGDQLLGY 558 Score = 37.7 bits (86), Expect = 0.097 Identities = 20/82 (24%), Positives = 37/82 (45%) Query: 621 VPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIV 680 +PL D ++ V TY N P++ +++PL + V GFEA G+ + Sbjct: 13 LPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVSGFEAEAAGRRVS 72 Query: 681 GEIKEKEEAQQEYLEAVTQGHG 702 +++ + +Q A+ G G Sbjct: 73 FQLQSRRRSQAACCRALGPGLG 94 >gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens] Length = 911 Score = 43.5 bits (101), Expect = 0.002 Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 3/132 (2%) Query: 604 KTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDD 663 ++ SS K D + + V + + + ++ A +V N ++ E + + Sbjct: 34 RSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPK 93 Query: 664 KAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLM--SQDAPDVFTVSVGNL 721 A + F +G +G+IK+K A ++Y +A G A L+ S + FT+ + + Sbjct: 94 TAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHL-TV 152 Query: 722 PPKAKVLIKITY 733 P++KV ++TY Sbjct: 153 NPQSKVTFQLTY 164 >gi|228008410 BEN domain containing 4 isoform b [Homo sapiens] Length = 441 Score = 42.0 bits (97), Expect = 0.005 Identities = 48/153 (31%), Positives = 63/153 (41%), Gaps = 25/153 (16%) Query: 1301 LFKKVSPWETSTSSFFPILAPAVGS-YLPPT------ARAHSPASLSFASYRQVASFGSA 1353 ++K+ SP+ S FP PA+ Y PT RA P FA + V+ S Sbjct: 17 IYKQRSPY--SVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSE 74 Query: 1354 APPRQFDASQFSQGPVPGTCADWIPQSA-SCPTG--------PPQNPPSSPYCGIVFSGS 1404 PP+QF A Q S P PG A S+ SC P Q PP+SP + S Sbjct: 75 PPPQQFQA-QSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASP------AAS 127 Query: 1405 SLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQL 1437 S SS + PG + GT + S +L Sbjct: 128 SSSSFAAVVRYGPGAAAAAGTGGTGSDSASLEL 160 >gi|148762950 BEN domain containing 4 isoform a [Homo sapiens] Length = 534 Score = 42.0 bits (97), Expect = 0.005 Identities = 48/153 (31%), Positives = 63/153 (41%), Gaps = 25/153 (16%) Query: 1301 LFKKVSPWETSTSSFFPILAPAVGS-YLPPT------ARAHSPASLSFASYRQVASFGSA 1353 ++K+ SP+ S FP PA+ Y PT RA P FA + V+ S Sbjct: 17 IYKQRSPY--SVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSE 74 Query: 1354 APPRQFDASQFSQGPVPGTCADWIPQSA-SCPTG--------PPQNPPSSPYCGIVFSGS 1404 PP+QF A Q S P PG A S+ SC P Q PP+SP + S Sbjct: 75 PPPQQFQA-QSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASP------AAS 127 Query: 1405 SLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQL 1437 S SS + PG + GT + S +L Sbjct: 128 SSSSFAAVVRYGPGAAAAAGTGGTGSDSASLEL 160 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 41.6 bits (96), Expect = 0.007 Identities = 44/153 (28%), Positives = 58/153 (37%), Gaps = 15/153 (9%) Query: 1315 FFPILAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCA 1374 F P +P V P ++A P SL+ A QV A+PP A+ Q P P Sbjct: 677 FSPPASPPVSPSATPPSQA--PPSLA-APPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733 Query: 1375 DWIPQSASCPTGPPQNPPSSPYC------GIVFSGSSLSSAQSAPLQHPGGFTTRPSAGT 1428 P PP +PP SP + + L S P P +P Sbjct: 734 P-----LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788 Query: 1429 FPELDSPQLHFSLPTDPDPIRGFGSYHPSASSP 1461 P L +P L +LP+ P G + PSAS P Sbjct: 789 PPALATPPLQ-ALPSPPASFPGQAPFSPSASLP 820 Score = 34.3 bits (77), Expect = 1.1 Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 6/213 (2%) Query: 1292 SCKPTAT-EPLFKKVSPWETSTSSFFPILAPAVGSYLPPTARAHSPASLSFASYRQVASF 1350 S P AT P K P ++ P+ A S T +P S S Q Sbjct: 300 SSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359 Query: 1351 GSAAPPRQFDASQFSQGPVPGTCADWIP--QSASCPTGPPQNPPSSPYCGIVFSGSSLSS 1408 A PP Q S + IP Q T P P SP + S + +S Sbjct: 360 PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA--LSSLQATTS 417 Query: 1409 AQSAPLQHPGGFTTRPSAGTFPELDSPQLHFSLPTDPDPIRGFGSYHPSASSPFHFQPSA 1468 S LQ F T T L SP S P D P++ S S P+ Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477 Query: 1469 ASLTANLRLPMASALPEALCSQSRTTPVDLCLL 1501 + L++ L + AL +L S S P+ ++ Sbjct: 478 SPLSSPLTIHPLQAL-SSLASHSPQAPLSSLIM 509 >gi|118498362 kinectin 1 isoform b [Homo sapiens] Length = 1306 Score = 41.2 bits (95), Expect = 0.009 Identities = 56/252 (22%), Positives = 98/252 (38%), Gaps = 32/252 (12%) Query: 79 KSIREKRLLDVKNYDPYKPLDITPPPDQKASSSEVKTEGLCPDSATEEEDTVELTEFGMQ 138 + + E LL V N + L IT + + + K E + A EE +L G Sbjct: 814 EELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKW 873 Query: 139 NVEIPHLPQDF-----EVAKYNTLEKVGMEGGQEAVVVELQCSRDSRDCPFLISSHFLLD 193 ++ + EVA++N E +E +V + + + ++ + Sbjct: 874 LQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKER---E 930 Query: 194 DGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLREHFTPEATQLASEQLQALLLEEV 253 + ++ Q + + +D ++ F++ IE+LK+Q + F P E+L ++ E Sbjct: 931 SDLSSKTQ--LLQDVQDENKLFKSQIEQLKQQNYQQASSFPPH------EELLKVISERE 982 Query: 254 MNSSTLSQEV--------------SDLVEMIW--AEALGHLEHMLLKPVNRISLNDVSKA 297 S L E+ +DL E W EAL E ML VN+ S + Sbjct: 983 KEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQV 1042 Query: 298 EGILLLVKAALK 309 E + L K LK Sbjct: 1043 EAVELEAKEVLK 1054 >gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens] Length = 1313 Score = 40.4 bits (93), Expect = 0.015 Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 10/106 (9%) Query: 598 YQLPDAKTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKY 657 YQ P SSSTK + S ++ ++ A +V N EA + Sbjct: 22 YQGPPVPASSSTKLLMTSYS----------MRSTVVSRYAHTLVTSVLFNPHAEAHEAIF 71 Query: 658 IFPLDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGA 703 L A + F IN K + E+KEK +A++ Y EA QG A Sbjct: 72 DLDLPHLAFISNFTMTINNKVYIAEVKEKHQAKKIYEEAHQQGKTA 117 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 40.4 bits (93), Expect = 0.015 Identities = 33/113 (29%), Positives = 46/113 (40%), Gaps = 7/113 (6%) Query: 1319 LAPAVGSYLP-PTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWI 1377 ++P++GS P P AH P S SY Q G +S SQG P C+ Sbjct: 532 MSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP--CSH-- 587 Query: 1378 PQSASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFP 1430 P + P G P P P + S ++LS+ + P G+ T G P Sbjct: 588 PSPSQGPQGAPY--PFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 40.4 bits (93), Expect = 0.015 Identities = 33/113 (29%), Positives = 46/113 (40%), Gaps = 7/113 (6%) Query: 1319 LAPAVGSYLP-PTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWI 1377 ++P++GS P P AH P S SY Q G +S SQG P C+ Sbjct: 532 MSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP--CSH-- 587 Query: 1378 PQSASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFP 1430 P + P G P P P + S ++LS+ + P G+ T G P Sbjct: 588 PSPSQGPQGAPY--PFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638 >gi|150417989 cyclin K isoform 1 [Homo sapiens] Length = 580 Score = 40.0 bits (92), Expect = 0.020 Identities = 43/153 (28%), Positives = 53/153 (34%), Gaps = 7/153 (4%) Query: 1317 PILAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADW 1376 P P + + PP AH P A+ G A PP DA+ + +P Sbjct: 352 PPKIPKIETTHPPLPPAHPPPD---RKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPA 408 Query: 1377 -IPQSASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSP 1435 + Q P PP PPSS G+ + S +S LQ T PS G P P Sbjct: 409 PVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMK-TEGPSYGALPPAYGP 467 Query: 1436 QLHFSLPTDPDPIRGFGSYHPSASSPFHFQPSA 1468 H LP P P P F P A Sbjct: 468 PAH--LPYHPHVYPPNPPPPPVPPPPASFPPPA 498 >gi|58530876 melanoma antigen family C, 1 [Homo sapiens] Length = 1142 Score = 39.7 bits (91), Expect = 0.026 Identities = 63/240 (26%), Positives = 92/240 (38%), Gaps = 32/240 (13%) Query: 1308 WETSTSSF-FPILAPA----VGSYLPPTARAHSPASLS----FASYRQVASFGSAAPPRQ 1358 WE S S FP P S P + S SLS F Q G A P Q Sbjct: 717 WEDSLSPLHFPQFPPQGEDFQSSLQSPVSICSSSTSLSLPQSFPESPQSPPEGPAQSPLQ 776 Query: 1359 FDASQFSQGPVPGTCADWIPQSASCPTGPPQNPPSSPYCGIVF---SGSSLSSAQSAPLQ 1415 S F T A + S P PP+ P SP V S +S S +QS+P+ Sbjct: 777 RPVSSFFSY----TLASLLQSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQSSPVS 832 Query: 1416 HPGGFTTRPSAGTFPE--LDSPQLHFSLPTDPDPIRGFGSYHPSASSPF-HFQPSAASLT 1472 T+ + + PE L SP + FS T P + +SSP + S+ +L Sbjct: 833 SFPSSTSSSLSKSSPESPLQSPVISFSSSTSLSP------FSEESSSPVDEYTSSSDTLL 886 Query: 1473 ANLRLPMASALPEALCSQSRTTPVDLCLLEESVGSLEGSRCPVFAFQSSDTESDELSEVL 1532 + L + +L E + P+ L+E V L + + T+++ L+ V+ Sbjct: 887 ESDSLTDSESLIE-------SEPLFTYTLDEKVDELARFLLLKYQVKQPITKAEMLTNVI 939 >gi|18959210 WIRE protein [Homo sapiens] Length = 440 Score = 38.5 bits (88), Expect = 0.057 Identities = 44/140 (31%), Positives = 58/140 (41%), Gaps = 22/140 (15%) Query: 1328 PPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWI-PQSASCPTG 1386 PP RA++P + + S AP + P+P T + P P Sbjct: 181 PPGRRANAPPT-------PLPMHSSKAPAYN------REKPLPPTPGQRLHPGREGPPAP 227 Query: 1387 PPQNPPSSPY-CGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGT---FPELDSPQLHFSLP 1442 PP PP SP SG SL+ P + P G PS+ T PEL PQ H SL Sbjct: 228 PPVKPPPSPVNIRTGPSGQSLAPPPP-PYRQPPGVPNGPSSPTNESAPEL--PQRHNSLH 284 Query: 1443 TD-PDPIRGFGSYHPSASSP 1461 P P+RG P+++SP Sbjct: 285 RKTPGPVRGLAPPPPTSASP 304 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 37.7 bits (86), Expect = 0.097 Identities = 48/168 (28%), Positives = 61/168 (36%), Gaps = 22/168 (13%) Query: 1319 LAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIP 1378 + PA S P T + +P A+ V GS + + Q PVP T P Sbjct: 193 VTPAPSSAPPGTPQLPTPGPTPSAT--AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 250 Query: 1379 QSASCPTGPPQ-NPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQL 1437 A P PP +PP P + PLQ G +PSA P P L Sbjct: 251 --ALHPQRPPSPHPPPHP-------------SPHPPLQPLTGSAGQPSA---PSHAQPPL 292 Query: 1438 HFSLPTDPDPIR-GFGSYHPSASSPFHFQPSAASLTANLRLPMASALP 1484 H P P ++ G HP PF P A+ A L A+A P Sbjct: 293 HGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 37.7 bits (86), Expect = 0.097 Identities = 48/168 (28%), Positives = 61/168 (36%), Gaps = 22/168 (13%) Query: 1319 LAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIP 1378 + PA S P T + +P A+ V GS + + Q PVP T P Sbjct: 747 VTPAPSSAPPGTPQLPTPGPTPSAT--AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 804 Query: 1379 QSASCPTGPPQ-NPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQL 1437 A P PP +PP P + PLQ G +PSA P P L Sbjct: 805 --ALHPQRPPSPHPPPHP-------------SPHPPLQPLTGSAGQPSA---PSHAQPPL 846 Query: 1438 HFSLPTDPDPIR-GFGSYHPSASSPFHFQPSAASLTANLRLPMASALP 1484 H P P ++ G HP PF P A+ A L A+A P Sbjct: 847 HGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 37.7 bits (86), Expect = 0.097 Identities = 48/168 (28%), Positives = 61/168 (36%), Gaps = 22/168 (13%) Query: 1319 LAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIP 1378 + PA S P T + +P A+ V GS + + Q PVP T P Sbjct: 747 VTPAPSSAPPGTPQLPTPGPTPSAT--AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 804 Query: 1379 QSASCPTGPPQ-NPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQL 1437 A P PP +PP P + PLQ G +PSA P P L Sbjct: 805 --ALHPQRPPSPHPPPHP-------------SPHPPLQPLTGSAGQPSA---PSHAQPPL 846 Query: 1438 HFSLPTDPDPIR-GFGSYHPSASSPFHFQPSAASLTANLRLPMASALP 1484 H P P ++ G HP PF P A+ A L A+A P Sbjct: 847 HGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 67,099,268 Number of Sequences: 37866 Number of extensions: 3192081 Number of successful extensions: 10521 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 20 Number of HSP's successfully gapped in prelim test: 142 Number of HSP's that attempted gapping in prelim test: 10215 Number of HSP's gapped (non-prelim): 390 length of query: 1724 length of database: 18,247,518 effective HSP length: 116 effective length of query: 1608 effective length of database: 13,855,062 effective search space: 22278939696 effective search space used: 22278939696 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.