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Search of human proteins with 112789550
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|112789550 poly (ADP-ribose) polymerase family, member 4
[Homo sapiens]
(1724 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo... 3455 0.0
gi|194306644 BCSC-1 isoform 1 [Homo sapiens] 161 4e-39
gi|38195080 BCSC-1 isoform 1 [Homo sapiens] 161 4e-39
gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo... 114 6e-25
gi|38195082 BCSC-1 isoform 2 [Homo sapiens] 114 6e-25
gi|210147462 von Willebrand factor A domain containing 5B1 [Homo... 105 3e-22
gi|110825963 poly (ADP-ribose) polymerase family, member 2 isofo... 103 1e-21
gi|110825961 poly (ADP-ribose) polymerase family, member 2 isofo... 103 1e-21
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo... 79 4e-14
gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo... 79 4e-14
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens] 70 2e-11
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [... 52 7e-06
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 48 9e-05
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 47 1e-04
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 47 2e-04
gi|222352129 von Willebrand factor A domain containing 5B2 [Homo... 47 2e-04
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens] 44 0.002
gi|228008410 BEN domain containing 4 isoform b [Homo sapiens] 42 0.005
gi|148762950 BEN domain containing 4 isoform a [Homo sapiens] 42 0.005
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 42 0.007
gi|118498362 kinectin 1 isoform b [Homo sapiens] 41 0.009
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens] 40 0.015
gi|55750053 atrophin-1 [Homo sapiens] 40 0.015
gi|55750041 atrophin-1 [Homo sapiens] 40 0.015
gi|150417989 cyclin K isoform 1 [Homo sapiens] 40 0.020
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 40 0.026
gi|18959210 WIRE protein [Homo sapiens] 39 0.057
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 38 0.097
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 38 0.097
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 38 0.097
>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
sapiens]
Length = 1724
Score = 3455 bits (8959), Expect = 0.0
Identities = 1724/1724 (100%), Positives = 1724/1724 (100%)
Query: 1 MVMGIFANCIFCLKVKYLPQQQKKKLQTDIKENGGKFSFSLNPQCTHIILDNADVLSQYQ 60
MVMGIFANCIFCLKVKYLPQQQKKKLQTDIKENGGKFSFSLNPQCTHIILDNADVLSQYQ
Sbjct: 1 MVMGIFANCIFCLKVKYLPQQQKKKLQTDIKENGGKFSFSLNPQCTHIILDNADVLSQYQ 60
Query: 61 LNSIQKNHVHIANPDFIWKSIREKRLLDVKNYDPYKPLDITPPPDQKASSSEVKTEGLCP 120
LNSIQKNHVHIANPDFIWKSIREKRLLDVKNYDPYKPLDITPPPDQKASSSEVKTEGLCP
Sbjct: 61 LNSIQKNHVHIANPDFIWKSIREKRLLDVKNYDPYKPLDITPPPDQKASSSEVKTEGLCP 120
Query: 121 DSATEEEDTVELTEFGMQNVEIPHLPQDFEVAKYNTLEKVGMEGGQEAVVVELQCSRDSR 180
DSATEEEDTVELTEFGMQNVEIPHLPQDFEVAKYNTLEKVGMEGGQEAVVVELQCSRDSR
Sbjct: 121 DSATEEEDTVELTEFGMQNVEIPHLPQDFEVAKYNTLEKVGMEGGQEAVVVELQCSRDSR 180
Query: 181 DCPFLISSHFLLDDGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLREHFTPEATQL 240
DCPFLISSHFLLDDGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLREHFTPEATQL
Sbjct: 181 DCPFLISSHFLLDDGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLREHFTPEATQL 240
Query: 241 ASEQLQALLLEEVMNSSTLSQEVSDLVEMIWAEALGHLEHMLLKPVNRISLNDVSKAEGI 300
ASEQLQALLLEEVMNSSTLSQEVSDLVEMIWAEALGHLEHMLLKPVNRISLNDVSKAEGI
Sbjct: 241 ASEQLQALLLEEVMNSSTLSQEVSDLVEMIWAEALGHLEHMLLKPVNRISLNDVSKAEGI 300
Query: 301 LLLVKAALKNGETAEQLQKMMTEFYRLIPHKGTMPKEVNLGLLAKKADLCQLIRDMVNVC 360
LLLVKAALKNGETAEQLQKMMTEFYRLIPHKGTMPKEVNLGLLAKKADLCQLIRDMVNVC
Sbjct: 301 LLLVKAALKNGETAEQLQKMMTEFYRLIPHKGTMPKEVNLGLLAKKADLCQLIRDMVNVC 360
Query: 361 ETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQIFRVGRV 420
ETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQIFRVGRV
Sbjct: 361 ETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQIFRVGRV 420
Query: 421 NETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSD 480
NETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSD
Sbjct: 421 NETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSD 480
Query: 481 SLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTASVT 540
SLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTASVT
Sbjct: 481 SLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTASVT 540
Query: 541 TDFEDDEFVVYKTNQVKMKYIIKFSMPGDQIKDFHPSDHTELEEYRPEFSNFSKVEDYQL 600
TDFEDDEFVVYKTNQVKMKYIIKFSMPGDQIKDFHPSDHTELEEYRPEFSNFSKVEDYQL
Sbjct: 541 TDFEDDEFVVYKTNQVKMKYIIKFSMPGDQIKDFHPSDHTELEEYRPEFSNFSKVEDYQL 600
Query: 601 PDAKTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFP 660
PDAKTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFP
Sbjct: 601 PDAKTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFP 660
Query: 661 LDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQDAPDVFTVSVGN 720
LDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQDAPDVFTVSVGN
Sbjct: 661 LDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQDAPDVFTVSVGN 720
Query: 721 LPPKAKVLIKITYITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTK 780
LPPKAKVLIKITYITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTK
Sbjct: 721 LPPKAKVLIKITYITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTK 780
Query: 781 QSFSLTMSIEMPYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYL 840
QSFSLTMSIEMPYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYL
Sbjct: 781 QSFSLTMSIEMPYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYL 840
Query: 841 PRMWVEKHPEKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIAL 900
PRMWVEKHPEKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIAL
Sbjct: 841 PRMWVEKHPEKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIAL 900
Query: 901 HALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTMAAEFIMSATPTMGNTDFWKTLRYL 960
HALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTMAAEFIMSATPTMGNTDFWKTLRYL
Sbjct: 901 HALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTMAAEFIMSATPTMGNTDFWKTLRYL 960
Query: 961 SLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCG 1020
SLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCG
Sbjct: 961 SLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCG 1020
Query: 1021 AGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFL 1080
AGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFL
Sbjct: 1021 AGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFL 1080
Query: 1081 NDRLLVYGFIPHCTQATLCALIQEKEFRTMVSTTELQKTTGTMIHKLAARALIRDYEDGI 1140
NDRLLVYGFIPHCTQATLCALIQEKEFRTMVSTTELQKTTGTMIHKLAARALIRDYEDGI
Sbjct: 1081 NDRLLVYGFIPHCTQATLCALIQEKEFRTMVSTTELQKTTGTMIHKLAARALIRDYEDGI 1140
Query: 1141 LHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDENESPFPDIPKVSELIAK 1200
LHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDENESPFPDIPKVSELIAK
Sbjct: 1141 LHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDENESPFPDIPKVSELIAK 1200
Query: 1201 EDVDFLPYMSWQGEPQEAVRNQSLLASSEWPELRLSKRKHRKIPFSKRKMELSQPEVSED 1260
EDVDFLPYMSWQGEPQEAVRNQSLLASSEWPELRLSKRKHRKIPFSKRKMELSQPEVSED
Sbjct: 1201 EDVDFLPYMSWQGEPQEAVRNQSLLASSEWPELRLSKRKHRKIPFSKRKMELSQPEVSED 1260
Query: 1261 FEEDGLGVLPAFTSNLERGGVEKLLDLSWTESCKPTATEPLFKKVSPWETSTSSFFPILA 1320
FEEDGLGVLPAFTSNLERGGVEKLLDLSWTESCKPTATEPLFKKVSPWETSTSSFFPILA
Sbjct: 1261 FEEDGLGVLPAFTSNLERGGVEKLLDLSWTESCKPTATEPLFKKVSPWETSTSSFFPILA 1320
Query: 1321 PAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIPQS 1380
PAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIPQS
Sbjct: 1321 PAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIPQS 1380
Query: 1381 ASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQLHFS 1440
ASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQLHFS
Sbjct: 1381 ASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQLHFS 1440
Query: 1441 LPTDPDPIRGFGSYHPSASSPFHFQPSAASLTANLRLPMASALPEALCSQSRTTPVDLCL 1500
LPTDPDPIRGFGSYHPSASSPFHFQPSAASLTANLRLPMASALPEALCSQSRTTPVDLCL
Sbjct: 1441 LPTDPDPIRGFGSYHPSASSPFHFQPSAASLTANLRLPMASALPEALCSQSRTTPVDLCL 1500
Query: 1501 LEESVGSLEGSRCPVFAFQSSDTESDELSEVLQDSCFLQIKCDTKDDSILCFLEVKEEDE 1560
LEESVGSLEGSRCPVFAFQSSDTESDELSEVLQDSCFLQIKCDTKDDSILCFLEVKEEDE
Sbjct: 1501 LEESVGSLEGSRCPVFAFQSSDTESDELSEVLQDSCFLQIKCDTKDDSILCFLEVKEEDE 1560
Query: 1561 IVCIQHWQDAVPWTELLSLQTEDGFWKLTPELGLILNLNTNGLHSFLKQKGIQSLGVKGR 1620
IVCIQHWQDAVPWTELLSLQTEDGFWKLTPELGLILNLNTNGLHSFLKQKGIQSLGVKGR
Sbjct: 1561 IVCIQHWQDAVPWTELLSLQTEDGFWKLTPELGLILNLNTNGLHSFLKQKGIQSLGVKGR 1620
Query: 1621 ECLLDLIATMLVLQFIRTRLEKEGIVFKSLMKMDDASISRNIPWAFEAIKQASEWVRRTE 1680
ECLLDLIATMLVLQFIRTRLEKEGIVFKSLMKMDDASISRNIPWAFEAIKQASEWVRRTE
Sbjct: 1621 ECLLDLIATMLVLQFIRTRLEKEGIVFKSLMKMDDASISRNIPWAFEAIKQASEWVRRTE 1680
Query: 1681 GQYPSICPRLELGNDWDSATKQLLGLQPISTVSPLHRVLHYSQG 1724
GQYPSICPRLELGNDWDSATKQLLGLQPISTVSPLHRVLHYSQG
Sbjct: 1681 GQYPSICPRLELGNDWDSATKQLLGLQPISTVSPLHRVLHYSQG 1724
>gi|194306644 BCSC-1 isoform 1 [Homo sapiens]
Length = 786
Score = 161 bits (408), Expect = 4e-39
Identities = 156/596 (26%), Positives = 270/596 (45%), Gaps = 53/596 (8%)
Query: 621 VPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIV 680
VPL+ + + I + VA V Y N+ VP+EA ++FP+D+ +AV FEA ++GK IV
Sbjct: 15 VPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIV 74
Query: 681 GEIKEKEEAQQEYLEAVTQGHGAYLMSQDAP--DVFTVSVGNLPPKAKVLIKITYITELS 738
E+++K +A+ Y +A++QGH A+L+ D+ DVF+ +VGNL P +K + + Y+ EL
Sbjct: 75 AELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELP 134
Query: 739 ILGTVGV-FFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTMSIEMPYVIEF 797
+ + F +PA + P Q +++ V+ + + S+ +I+ + IE
Sbjct: 135 LEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEK 194
Query: 798 I-----FSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEK-HPEK 851
+ S T L + +T A +S G D L I + + P + +E P
Sbjct: 195 VQSNCPLSPTEYLGEDKT--SAQVSLAAGHKFDRD-VELLIYYNEVHTPSVVLEMGMPNM 251
Query: 852 E------SEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQ---------AK 896
+ + M+ F P++ D P E I +D S SM+ Q AK
Sbjct: 252 KPGHLMGDPSAMVSFYPNIPEDQPSNTC-GEFIFLMDRSGSMQSPMSSQDTSQLRIQAAK 310
Query: 897 QIALHALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTM--AAEFIMSATPTMGNTDFW 954
+ + L + NI FG+ Y+ F T TM A + +G T+
Sbjct: 311 ETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEIL 370
Query: 955 KTLR--YLSLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHV 1012
L+ Y P + + +DG + D ++ V+ +R R F+ GIG + +
Sbjct: 371 APLQNIYRGPSIPGH-PLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSL 429
Query: 1013 LRILSQCGAGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAP 1072
++ +++ G E+ K + + + + R P VS+ W L P + + +P
Sbjct: 430 IKGIARASGGTSEFITGKDR--MQSKALRTLKRSLQPVVEDVSLSW-HLPPGLSAKMLSP 486
Query: 1073 AQVPSLFLNDRLLVY----GFIPHC-TQATLCA--LIQEKEFRTMVS-TTELQKTTGTMI 1124
Q +F RL+ Y G +P T +C +Q K F V+ + + I
Sbjct: 487 EQT-VIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTI 545
Query: 1125 HKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEK 1180
H+LAA++L++ + G+ ET KK L LS E+ +I+ FT+F+A+ K
Sbjct: 546 HRLAAKSLLQTKDMGL---RETPASDKKDAL-----NLSLESGVISSFTAFIAINK 593
>gi|38195080 BCSC-1 isoform 1 [Homo sapiens]
Length = 786
Score = 161 bits (408), Expect = 4e-39
Identities = 156/596 (26%), Positives = 270/596 (45%), Gaps = 53/596 (8%)
Query: 621 VPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIV 680
VPL+ + + I + VA V Y N+ VP+EA ++FP+D+ +AV FEA ++GK IV
Sbjct: 15 VPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIV 74
Query: 681 GEIKEKEEAQQEYLEAVTQGHGAYLMSQDAP--DVFTVSVGNLPPKAKVLIKITYITELS 738
E+++K +A+ Y +A++QGH A+L+ D+ DVF+ +VGNL P +K + + Y+ EL
Sbjct: 75 AELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELP 134
Query: 739 ILGTVGV-FFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTMSIEMPYVIEF 797
+ + F +PA + P Q +++ V+ + + S+ +I+ + IE
Sbjct: 135 LEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEK 194
Query: 798 I-----FSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEK-HPEK 851
+ S T L + +T A +S G D L I + + P + +E P
Sbjct: 195 VQSNCPLSPTEYLGEDKT--SAQVSLAAGHKFDRD-VELLIYYNEVHTPSVVLEMGMPNM 251
Query: 852 E------SEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQ---------AK 896
+ + M+ F P++ D P E I +D S SM+ Q AK
Sbjct: 252 KPGHLMGDPSAMVSFYPNIPEDQPSNTC-GEFIFLMDRSGSMQSPMSSQDTSQLRIQAAK 310
Query: 897 QIALHALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTM--AAEFIMSATPTMGNTDFW 954
+ + L + NI FG+ Y+ F T TM A + +G T+
Sbjct: 311 ETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEIL 370
Query: 955 KTLR--YLSLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHV 1012
L+ Y P + + +DG + D ++ V+ +R R F+ GIG + +
Sbjct: 371 APLQNIYRGPSIPGH-PLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSL 429
Query: 1013 LRILSQCGAGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAP 1072
++ +++ G E+ K + + + + R P VS+ W L P + + +P
Sbjct: 430 IKGIARASGGTSEFITGKDR--MQSKALRTLKRSLQPVVEDVSLSW-HLPPGLSAKMLSP 486
Query: 1073 AQVPSLFLNDRLLVY----GFIPHC-TQATLCA--LIQEKEFRTMVS-TTELQKTTGTMI 1124
Q +F RL+ Y G +P T +C +Q K F V+ + + I
Sbjct: 487 EQT-VIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTI 545
Query: 1125 HKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEK 1180
H+LAA++L++ + G+ ET KK L LS E+ +I+ FT+F+A+ K
Sbjct: 546 HRLAAKSLLQTKDMGL---RETPASDKKDAL-----NLSLESGVISSFTAFIAINK 593
>gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo
sapiens]
Length = 1014
Score = 114 bits (286), Expect = 6e-25
Identities = 150/624 (24%), Positives = 258/624 (41%), Gaps = 103/624 (16%)
Query: 21 QQKKKLQTDIKENGGKFSFSLNPQCTHIILDNADVLSQYQLNSIQKNHVHIANPDFIW-- 78
+ K +++ I++ GGK + + N I ++ +++ ++ + + DF+
Sbjct: 403 RNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDV 462
Query: 79 ----KSIREKRLLDVKNYDPY------KPLDITPPPDQ------KASSSEVKTEGLCPDS 122
KS++E L + + P+ +P+++ P + K S +VK EG+
Sbjct: 463 SASTKSLQELFLAHILS--PWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGI---- 516
Query: 123 ATEEEDTVELTEFGMQNVEIPHLPQDFEVAKYNTLEKVGMEGGQEAVVVE---------- 172
+ E ++LT G V+ P + LEK G +V+
Sbjct: 517 -NKSEKRMKLTLKGGAAVD----PDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYK 571
Query: 173 LQCSRDSRDCPFLISSHFLLDDGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLR-- 230
LQ D ++ + I + + + + EDA E+F EE + +
Sbjct: 572 LQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNF 631
Query: 231 ----EHFTP-EATQLASEQLQALLLEEVMNSSTLSQEVSDLVEMIW-----AEALGHLEH 280
+ F P E E+ L S L + V DL++MI+ +A+ E
Sbjct: 632 TKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEI 691
Query: 281 MLLK-PVNRISLNDVSKAEGILLLVKAALKNGETAEQLQKMMTEFYRLIPHKGTMPKEVN 339
L K P+ ++S + A IL V+ A+ G + Q+ + FY LIPH M K
Sbjct: 692 DLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPP- 750
Query: 340 LGLLAKKADLCQLIRDMV-NVCETNLS----------KPNPPSLAKYRALRCKIEHVEQN 388
L AD Q +M+ N+ + ++ P Y L+ I+ V+++
Sbjct: 751 ---LLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRD 807
Query: 389 TEEFLRVRKEVLQNH---HSKSPVDVLQIFRVGRVNETTEF--LSKLGNVRPLLHGSPVQ 443
+EE +RK V H H+ ++V+ IF++ R E + +L N R L HGS
Sbjct: 808 SEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTT 867
Query: 444 NIVGILCRGL-LLPKVVEDRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLI 502
N GIL +GL + P G G GIYF+D +S S Y H + D L+L+
Sbjct: 868 NFAGILSQGLRIAPPEAPVTGYM------FGKGIYFADMVSKSANYCHTSQGDPIGLILL 921
Query: 503 CDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQT-----ASVTTDFED------------ 545
+VALG +L +++ P G SV G+ +T A+++ D D
Sbjct: 922 GEVALGNMYELKHAS-HISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVN 980
Query: 546 ------DEFVVYKTNQVKMKYIIK 563
+E++VY QV +KY++K
Sbjct: 981 DTSLLYNEYIVYDIAQVNLKYLLK 1004
>gi|38195082 BCSC-1 isoform 2 [Homo sapiens]
Length = 415
Score = 114 bits (286), Expect = 6e-25
Identities = 107/406 (26%), Positives = 183/406 (45%), Gaps = 33/406 (8%)
Query: 621 VPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIV 680
VPL+ + + I + VA V Y N+ VP+EA ++FP+D+ +AV FEA ++GK IV
Sbjct: 15 VPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIV 74
Query: 681 GEIKEKEEAQQEYLEAVTQGHGAYLMSQDAP--DVFTVSVGNLPPKAKVLIKITYITELS 738
E+++K +A+ Y +A++QGH A+L+ D+ DVF+ +VGNL P +K + + Y+ EL
Sbjct: 75 AELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELP 134
Query: 739 ILGTVGV-FFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTMSIEMPYVIEF 797
+ + F +PA + P Q +++ V+ + + S+ +I+ + IE
Sbjct: 135 LEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEK 194
Query: 798 I-----FSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEK-HPEK 851
+ S T L + +T A +S G D L I + + P + +E P
Sbjct: 195 VQSNCPLSPTEYLGEDKT--SAQVSLAAGHKFDRD-VELLIYYNEVHTPSVVLEMGMPNM 251
Query: 852 E------SEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQ---------AK 896
+ + M+ F P++ D P E I +D S SM+ Q AK
Sbjct: 252 KPGHLMGDPSAMVSFYPNIPEDQPSNTC-GEFIFLMDRSGSMQSPMSSQDTSQLRIQAAK 310
Query: 897 QIALHALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTM--AAEFIMSATPTMGNTDFW 954
+ + L + NI FG+ Y+ F T TM A + +G T+
Sbjct: 311 ETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEIL 370
Query: 955 KTLR--YLSLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTR 998
L+ Y P + + +DG + D ++ V+ +R R
Sbjct: 371 APLQNIYRGPSIPGH-PLQLFVFTDGEVTDTFSVIKEVRINRQKHR 415
>gi|210147462 von Willebrand factor A domain containing 5B1 [Homo
sapiens]
Length = 1215
Score = 105 bits (263), Expect = 3e-22
Identities = 121/543 (22%), Positives = 216/543 (39%), Gaps = 100/543 (18%)
Query: 644 TYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEA------V 697
TY N P + +++PLD+ V GFEA I + + +IK+K + + + +A
Sbjct: 36 TYGNLEAQPFQGLFVYPLDECTTVIGFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPT 95
Query: 698 TQGH---------------GAYLMSQDAPDV-FTVSVGNLPPKAKVLIKITYITELSILG 741
G+ G + +D + F ++G + P V I I+ +EL L
Sbjct: 96 VTGNILQDGVSIAPHSCTPGKVTLDEDLERILFVANLGTIAPMENVTIFISTSSELPTLP 155
Query: 742 TVGV-FFMPATVAPW------QQDKALNENLQD------------TVEKICIKEIGTKQ- 781
+ V +PA AP + N+ Q + K+C+ + +
Sbjct: 156 SGAVRVLLPAVCAPTVPQFCTKSTGTSNQQAQGKDRHCFGAWAPGSWNKLCLATLLNTEV 215
Query: 782 ------SFSLTMSIEMPYVIEFIFSDTHELKQKRT----DCKAVISTMEGSSLDSSGFSL 831
F+ + I P ++ + S THE++ K++I T+ +
Sbjct: 216 SNPMEYEFNFQLEIRGPCLLAGVESPTHEIRADAAPSARSAKSIIITLANKHTFDRPVEI 275
Query: 832 HIGLSAAYLPRMWVEK--------------------------HPEKESE----------- 854
I S ++P + +EK E+++E
Sbjct: 276 LIHPSEPHMPHVLIEKGDMTLGEFDQHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDIP 335
Query: 855 ---ACMLVFQPDLDVDLPDLA-SESEVIICLDCSSSMEGVTFLQAKQIALHALSLVGEKQ 910
ML F PDL P L + E I +D SSSM G++ + K L AL +
Sbjct: 336 HHSVIMLNFCPDLQSVQPCLRKAHGEFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPAC 395
Query: 911 KVNIIQFGTGYKELFSYPKHITSNT--MAAEFIMSATPTMGNTDFWKTLRYLSLLYPARG 968
NII FG+ +K LF + + ++ MA + I MG T+ L+++ RG
Sbjct: 396 LFNIIGFGSTFKSLFPSSQTYSEDSLAMACDDIQRMKADMGGTNILSPLKWVIRQPVHRG 455
Query: 969 -SRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCGAGVFEYF 1027
R + +++DG + + L+LV+ TR ++ GIG +++ L+ G E
Sbjct: 456 HPRLLFVITDGAVNNTGKVLELVRNHAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELL 515
Query: 1028 NAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFLNDRLLVY 1087
+ + ++ + + +P V+V+W + P+ E L +P SLF +RL+ Y
Sbjct: 516 MEGER--LQPKMVKSLKKAMAPVLSDVTVEW--IFPETTEVLVSPVSASSLFPGERLVGY 571
Query: 1088 GFI 1090
G +
Sbjct: 572 GIV 574
Score = 35.0 bits (79), Expect = 0.63
Identities = 28/111 (25%), Positives = 48/111 (43%), Gaps = 9/111 (8%)
Query: 1125 HKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDEN 1184
H LAARA+IRD+E E E ++ S + SK ++I+++T+FV V+
Sbjct: 852 HHLAARAIIRDFEQLAEREGEIEQGSNRRYQVS-ALHTSKACNIISKYTAFVPVDVSKSR 910
Query: 1185 ESP----FPDIPKVSELIAKEDVDFLPYMSWQGEPQEAVRNQSLLASSEWP 1231
P +P+ ++ + W+G R Q++L P
Sbjct: 911 YLPTVVEYPNSGAALRMLGSRAL----AQQWRGTSSGFGRPQTMLGEDSAP 957
>gi|110825963 poly (ADP-ribose) polymerase family, member 2 isoform
2 [Homo sapiens]
Length = 570
Score = 103 bits (258), Expect = 1e-21
Identities = 90/351 (25%), Positives = 148/351 (42%), Gaps = 52/351 (14%)
Query: 257 STLSQEVSDLVEMIWAEALGHLEHMLLK--------PVNRISLNDVSKAEGILLLVKAAL 308
S L V +L+++I + +E M+++ P+ ++++ + L ++ +
Sbjct: 219 SQLDLRVQELIKLICN--VQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCI 276
Query: 309 KNGETAEQLQKMMTEFYRLIPHK---GTMPKEVNLGLLAKKADLCQLIRDM---VNVCET 362
+ G+ L + EFY IPH T P L++K L + + D+ + + +T
Sbjct: 277 RAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKT 336
Query: 363 NLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNH---HSKSPVDVLQIFRVGR 419
L P P YR L C + ++ + EF + + + H HS + +L +F V +
Sbjct: 337 ELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEK 396
Query: 420 VNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGL-LLPKVVEDRGVQRTDVGNLGSGIYF 478
E F L N L HGS + N VGIL GL + P G G GIYF
Sbjct: 397 DGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYM------FGKGIYF 450
Query: 479 SDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTAS 538
+D S S Y T LLL+ +VALG+C +L E + G S G+ + A
Sbjct: 451 ADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAP 510
Query: 539 VTTDF--------------------------EDDEFVVYKTNQVKMKYIIK 563
+ F +E++VY NQV+M+Y++K
Sbjct: 511 SSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLK 561
>gi|110825961 poly (ADP-ribose) polymerase family, member 2 isoform
1 [Homo sapiens]
Length = 583
Score = 103 bits (258), Expect = 1e-21
Identities = 90/351 (25%), Positives = 148/351 (42%), Gaps = 52/351 (14%)
Query: 257 STLSQEVSDLVEMIWAEALGHLEHMLLK--------PVNRISLNDVSKAEGILLLVKAAL 308
S L V +L+++I + +E M+++ P+ ++++ + L ++ +
Sbjct: 232 SQLDLRVQELIKLICN--VQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCI 289
Query: 309 KNGETAEQLQKMMTEFYRLIPHK---GTMPKEVNLGLLAKKADLCQLIRDM---VNVCET 362
+ G+ L + EFY IPH T P L++K L + + D+ + + +T
Sbjct: 290 RAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKT 349
Query: 363 NLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNH---HSKSPVDVLQIFRVGR 419
L P P YR L C + ++ + EF + + + H HS + +L +F V +
Sbjct: 350 ELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEK 409
Query: 420 VNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGL-LLPKVVEDRGVQRTDVGNLGSGIYF 478
E F L N L HGS + N VGIL GL + P G G GIYF
Sbjct: 410 DGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYM------FGKGIYF 463
Query: 479 SDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTAS 538
+D S S Y T LLL+ +VALG+C +L E + G S G+ + A
Sbjct: 464 ADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAP 523
Query: 539 VTTDF--------------------------EDDEFVVYKTNQVKMKYIIK 563
+ F +E++VY NQV+M+Y++K
Sbjct: 524 SSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLK 574
>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform
b [Homo sapiens]
Length = 533
Score = 79.0 bits (193), Expect = 4e-14
Identities = 88/421 (20%), Positives = 174/421 (41%), Gaps = 75/421 (17%)
Query: 209 EDASEYFENYIEELKKQGFLLREHFTPEATQLASEQLQA----------------LLLEE 252
EDA + FE E K + R+HF + ++QA + +
Sbjct: 119 EDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTK 178
Query: 253 VMNSSTLSQEVSDLVEMIWAEALGHLEHMLLK------PVNRISLNDVSKAEGILLLVKA 306
+ +L L+ I+++ + L+ P+ ++S +++ L ++
Sbjct: 179 RVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEE 238
Query: 307 ALKNG-ETAEQLQKMMTEFYRLIPHK--GTMPKEVNLG-LLAKKADLCQLIRDM------ 356
ALK + + L+++ + FY +IPH + P +N LL K D+ ++ D+
Sbjct: 239 ALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQAL 298
Query: 357 --VNVCETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQI 414
V+ E + + P Y+ L+C+++ ++ E+ ++ + Q + + I
Sbjct: 299 QAVSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHI 358
Query: 415 FRVGRVNETTEFL--SKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNL 472
++V + E F SKLGN + L HG+ + + IL GL +++ G G +
Sbjct: 359 WKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGL---RIMPHSG------GRV 409
Query: 473 GSGIYFSDSLSTSIKYSHPGETDGTRL--LLICDVALGKCMDLHEKDFSLTEAPPGYDSV 530
G GIYF+ S S Y + + + + +VALG+ ++ + SL PPG+DSV
Sbjct: 410 GKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSV 469
Query: 531 HGVSQTASVTTD----------------------------FEDDEFVVYKTNQVKMKYII 562
T T F E+++Y+ +Q +++Y++
Sbjct: 470 IARGHTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLL 529
Query: 563 K 563
+
Sbjct: 530 E 530
>gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform
a [Homo sapiens]
Length = 540
Score = 79.0 bits (193), Expect = 4e-14
Identities = 88/421 (20%), Positives = 174/421 (41%), Gaps = 75/421 (17%)
Query: 209 EDASEYFENYIEELKKQGFLLREHFTPEATQLASEQLQA----------------LLLEE 252
EDA + FE E K + R+HF + ++QA + +
Sbjct: 126 EDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTK 185
Query: 253 VMNSSTLSQEVSDLVEMIWAEALGHLEHMLLK------PVNRISLNDVSKAEGILLLVKA 306
+ +L L+ I+++ + L+ P+ ++S +++ L ++
Sbjct: 186 RVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEE 245
Query: 307 ALKNG-ETAEQLQKMMTEFYRLIPHK--GTMPKEVNLG-LLAKKADLCQLIRDM------ 356
ALK + + L+++ + FY +IPH + P +N LL K D+ ++ D+
Sbjct: 246 ALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQAL 305
Query: 357 --VNVCETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQI 414
V+ E + + P Y+ L+C+++ ++ E+ ++ + Q + + I
Sbjct: 306 QAVSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHI 365
Query: 415 FRVGRVNETTEFL--SKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNL 472
++V + E F SKLGN + L HG+ + + IL GL +++ G G +
Sbjct: 366 WKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGL---RIMPHSG------GRV 416
Query: 473 GSGIYFSDSLSTSIKYSHPGETDGTRL--LLICDVALGKCMDLHEKDFSLTEAPPGYDSV 530
G GIYF+ S S Y + + + + +VALG+ ++ + SL PPG+DSV
Sbjct: 417 GKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSV 476
Query: 531 HGVSQTASVTTD----------------------------FEDDEFVVYKTNQVKMKYII 562
T T F E+++Y+ +Q +++Y++
Sbjct: 477 IARGHTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLL 536
Query: 563 K 563
+
Sbjct: 537 E 537
>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
Length = 930
Score = 69.7 bits (169), Expect = 2e-11
Identities = 127/613 (20%), Positives = 237/613 (38%), Gaps = 60/613 (9%)
Query: 616 ASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFIN 675
A N + + + + R+ A +V N+++ EA + L KA + F I+
Sbjct: 28 AEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRANTVQEATFQMELPKKAFITNFSMIID 87
Query: 676 GKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQDAPDV--FTVSVGNLPPKAKVLIKITY 733
G G IKEK EAQ +Y AV +G A L+ ++ F VSV ++ P AK+ ++ Y
Sbjct: 88 GMTYPGIIKEKAEAQAQYSAAVAKGKSAGLVKATGRNMEQFQVSV-SVAPNAKITFELVY 146
Query: 734 ITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTMSIEM-- 791
E + +GV+ + V P Q K L ++ E I + T+ +F ++
Sbjct: 147 --EELLKRRLGVYELLLKVRPQQLVKHLQMDIH-IFEPQGISFLETESTFMTNQLVDALT 203
Query: 792 ----PYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEK 847
F T +QK + + + ++G+ + + + +S +
Sbjct: 204 TWQNKTKAHIRFKPTLSQQQKSPEQQETV--LDGNLI--IRYDVDRAISGGSI------- 252
Query: 848 HPEKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIALHALSLVG 907
+ E+ + F P+ +P V+ +D S SM G Q ++ + L +
Sbjct: 253 --QIENGYFVHYFAPEGLTTMP-----KNVVFVIDKSGSMSGRKIQQTREALIKILDDLS 305
Query: 908 EKQKVNIIQFGTGYKELF-SYPKHITSNTMAAEFIMSATPTMGNTDFWKT-LRYLSLL-- 963
+ + N+I F T + S N A + +G T+ L + LL
Sbjct: 306 PRDQFNLIVFSTEATQWRPSLVPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDS 365
Query: 964 ------YPARGSRNILLVSD-----GHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHV 1012
P I+L++D G S+ + + LF G G +
Sbjct: 366 SNQEERLPEGSVSLIILLTDGDPTVGETNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAF 425
Query: 1013 LRILSQCGAGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAP 1072
L L+ G+ + S + Q++D + +P +V+ ++ + V E Q
Sbjct: 426 LEKLALDNGGLARRIHEDSDSA--LQLQDFYQEVANPLLTAVTFEYP--SNAVEEVTQNN 481
Query: 1073 AQVPSLFLNDRLLVYGFI----PHCTQATLCALI--QEKEFRTMVSTTELQ---KTTGTM 1123
++ LF ++V G + P AT+ + Q F+T S E + ++ +
Sbjct: 482 FRL--LFKGSEMVVAGKLQDRGPDVLTATVSGKLPTQNITFQTESSVAEQEAEFQSPKYI 539
Query: 1124 IHKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDE 1183
H R +L + ++ + +Q L++ + LS S +T TS V + D+
Sbjct: 540 FHNFMERLWAYLTIQQLLEQTVSASDADQQALRNQALNLSLAYSFVTPLTSMVVTKPDDQ 599
Query: 1184 NESPFPDIPKVSE 1196
+S + P E
Sbjct: 600 EQSQVAEKPMEGE 612
>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [Homo
sapiens]
Length = 890
Score = 51.6 bits (122), Expect = 7e-06
Identities = 127/620 (20%), Positives = 231/620 (37%), Gaps = 69/620 (11%)
Query: 610 KAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCG 669
K L + N + + I ++ A +V N++ E + L A +
Sbjct: 32 KRSLPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELPKTAFITN 91
Query: 670 FEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQDAP--DVFTVSVGNLPPKAKV 727
F I+G G +KEKE A+++Y +AV+QG A L+ + FTVSV N+ +KV
Sbjct: 92 FTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSV-NVAAGSKV 150
Query: 728 LIKITYITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTM 787
++TY E + G + M V P Q K + D E I + + SF
Sbjct: 151 TFELTY--EELLKRHKGKYEMYLKVQPKQLVKHFEIEV-DIFEPQGISMLDAEASFITND 207
Query: 788 SIEMPYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEK 847
+ F H + D + T S L+ + Y
Sbjct: 208 LLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGD-------FTITYDVNRESPG 260
Query: 848 HPEKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIALHALSLVG 907
+ + + + F P LP V +D S SM G Q K+ L L +
Sbjct: 261 NVQIVNGYFVHFFAPQ---GLP--VVPKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQ 315
Query: 908 EKQKVNIIQFGTGYKELFSYPKHIT----SNTMAAEFIMSATPTMGNTDFWK-TLRYLSL 962
E+ +N I F ++ ++ +H+ N A + + G T+ LR +S+
Sbjct: 316 EEDYLNFILFS---GDVSTWKEHLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGISM 372
Query: 963 L--------YPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTR--------LFACGIGS 1006
L P R + +++++DG D ++ ++ + + R L+ G G+
Sbjct: 373 LNKAREEHRIPERSTSIVIMLTDG---DANVGESRPEKIQENVRNAIGGKFPLYNLGFGN 429
Query: 1007 TANRHVLRILSQCGAGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVP 1066
N + L ++ G S Q++ + +P V +++ + +
Sbjct: 430 NLNYNFLENMALENHGFARRIYEDSDAD--LQLQGFYEEVANPLLTGVEMEYPE--NAIL 485
Query: 1067 EALQAPAQVPSLFLNDRLLVYGFIPHCTQATLCALIQ------EKEFRTMVSTTELQKTT 1120
+ Q Q + ++V G + + A ++ + F V E++K
Sbjct: 486 DLTQNTYQ--HFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEVDMKEMEKAL 543
Query: 1121 -------GTMIHKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFT 1173
G I +L A I + +L + + +H +K+ L + + LS + +T T
Sbjct: 544 QERDYIFGNYIERLWAYLTI----EQLLEKRKNAHGEEKENLTARALDLSLKYHFVTPLT 599
Query: 1174 SFVAVEKRD-ENESPFPDIP 1192
S V + D E+E D P
Sbjct: 600 SMVVTKPEDNEDERAIADKP 619
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 47.8 bits (112), Expect = 9e-05
Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 30/162 (18%)
Query: 419 RVNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLGSGIYF 478
R E +E N R L HGSP N + + K ++R G G+GIYF
Sbjct: 1012 RRKEVSEENHNHANERMLFHGSPFVNAI--------IHKGFDERHAYIG--GMFGAGIYF 1061
Query: 479 SDSLSTSIKYSHPGETDGT--------------RLLLICDVALGKCMDLHEKDFSLTEAP 524
+++ S S +Y + G GT R LL C V LGK L + +P
Sbjct: 1062 AENSSKSNQYVY-GIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSF-LQFSAMKMAHSP 1119
Query: 525 PGYDSVHGVSQTASVTTDFEDDEFVVYKTNQVKMKYIIKFSM 566
PG+ SV G + E+V+Y+ Q +Y+I + +
Sbjct: 1120 PGHHSVTGRPSVNGLAL----AEYVIYRGEQAYPEYLITYQI 1157
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 47.4 bits (111), Expect = 1e-04
Identities = 54/195 (27%), Positives = 76/195 (38%), Gaps = 32/195 (16%)
Query: 1305 VSPWETSTSSFFPILAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQF 1364
++PW + + +P+VGS + P A SP++ S DAS F
Sbjct: 1517 MTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAAS-------------------DASGF 1557
Query: 1365 SQGPVPGTCADWIPQSASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPL---QHPGGFT 1421
S PG W P P P PSSPY S S + ++P + PGG+T
Sbjct: 1558 S----PGYSPAWSP----TPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYT 1609
Query: 1422 TR-PSAGTFPELDSPQLHFSLPTDPDPIRGFGSYHPSASSPFHFQPSAASLTANLRLPMA 1480
+ PS SP PT P+ SY P++ S PS S T+ P +
Sbjct: 1610 PQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPS-YSPTSPSYSPTS 1668
Query: 1481 SALPEALCSQSRTTP 1495
+ S S T+P
Sbjct: 1669 PSYSPTSPSYSPTSP 1683
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 47.0 bits (110), Expect = 2e-04
Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 30/162 (18%)
Query: 419 RVNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLGSGIYF 478
R E +E N R L HGSP N + + K ++R G G+GIYF
Sbjct: 1165 RQKEVSEENHNHHNERMLFHGSPFINAI--------IHKGFDERHAYIG--GMFGAGIYF 1214
Query: 479 SDSLSTSIKYSHPGETDGT--------------RLLLICDVALGKCMDLHEKDFSLTEAP 524
+++ S S +Y + G GT R +L C V LGK L + AP
Sbjct: 1215 AENSSKSNQYVY-GIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSF-LQFSTMKMAHAP 1272
Query: 525 PGYDSVHGVSQTASVTTDFEDDEFVVYKTNQVKMKYIIKFSM 566
PG+ SV G + E+V+Y+ Q +Y+I + +
Sbjct: 1273 PGHHSVIGRPSVNGLAY----AEYVIYRGEQAYPEYLITYQI 1310
Score = 33.5 bits (75), Expect = 1.8
Identities = 36/133 (27%), Positives = 52/133 (39%), Gaps = 13/133 (9%)
Query: 1295 PTATEPLFKKVSPWETSTSSFFPILAPAVGSYLP-------PTARAHSPASL---SFASY 1344
P + L +P + S P +P G LP P R SP + S S
Sbjct: 33 PPLSPGLAPGTTPASPTASGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDGTSCCST 92
Query: 1345 RQVASFGSAAP--PRQFDASQFSQGPVP-GTCADWIPQSASCPTGPPQNPPSSPYCGIVF 1401
+AAP P +S P P G+ ++ P S+S PT + PSSP +
Sbjct: 93 TSTICTVAAAPVVPAVSTSSAAGVAPNPAGSGSNNSPSSSSSPTSSSSSSPSSPGSSLAE 152
Query: 1402 SGSSLSSAQSAPL 1414
S + + +APL
Sbjct: 153 SPEAAGVSSTAPL 165
>gi|222352129 von Willebrand factor A domain containing 5B2 [Homo
sapiens]
Length = 1242
Score = 46.6 bits (109), Expect = 2e-04
Identities = 58/240 (24%), Positives = 102/240 (42%), Gaps = 26/240 (10%)
Query: 858 LVFQPDLDVDLPDLASES-EVIICLDCSSSMEGVTFLQAKQIALHALSLVGEKQKVNIIQ 916
L F PDL L + + E++ LD SS + K + A+ + + +N+
Sbjct: 335 LSFCPDLSSKPGHLGTATRELLFLLDSSS-------VAHKDAIVLAVKSLPPQTLINLAV 387
Query: 917 FGTGYKELFSYPKHITSNTMAAEFIMSATPTM----GNTDF-----WKTLRYLSLLYPAR 967
FGT + LF P+ + A + I + T+ G D W + YP +
Sbjct: 388 FGTLVQPLF--PESRPCSDDAVQLICESIETLQVPSGPPDVLAALDWAVGQPQHRAYPRQ 445
Query: 968 GSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCGAGVFEYF 1027
+L + TL+L++ R R F+ G+G T ++ +L+ LS G + +
Sbjct: 446 --LFLLTAASPMAATTHRTLELMRWHRGTARCFSFGLGPTCHQ-LLQGLSALSRG--QAY 500
Query: 1028 NAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFLNDRLLVY 1087
+ + + + + P+ +SV W PD EAL P ++P+L+ D+LL Y
Sbjct: 501 FLRPGQRLQPMLVQALRKALEPALSDISVDW--FVPDTVEALLTPREIPALYPGDQLLGY 558
Score = 37.7 bits (86), Expect = 0.097
Identities = 20/82 (24%), Positives = 37/82 (45%)
Query: 621 VPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIV 680
+PL D ++ V TY N P++ +++PL + V GFEA G+ +
Sbjct: 13 LPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVSGFEAEAAGRRVS 72
Query: 681 GEIKEKEEAQQEYLEAVTQGHG 702
+++ + +Q A+ G G
Sbjct: 73 FQLQSRRRSQAACCRALGPGLG 94
>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
Length = 911
Score = 43.5 bits (101), Expect = 0.002
Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Query: 604 KTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDD 663
++ SS K D + + V + + + ++ A +V N ++ E + +
Sbjct: 34 RSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPK 93
Query: 664 KAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLM--SQDAPDVFTVSVGNL 721
A + F +G +G+IK+K A ++Y +A G A L+ S + FT+ + +
Sbjct: 94 TAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHL-TV 152
Query: 722 PPKAKVLIKITY 733
P++KV ++TY
Sbjct: 153 NPQSKVTFQLTY 164
>gi|228008410 BEN domain containing 4 isoform b [Homo sapiens]
Length = 441
Score = 42.0 bits (97), Expect = 0.005
Identities = 48/153 (31%), Positives = 63/153 (41%), Gaps = 25/153 (16%)
Query: 1301 LFKKVSPWETSTSSFFPILAPAVGS-YLPPT------ARAHSPASLSFASYRQVASFGSA 1353
++K+ SP+ S FP PA+ Y PT RA P FA + V+ S
Sbjct: 17 IYKQRSPY--SVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSE 74
Query: 1354 APPRQFDASQFSQGPVPGTCADWIPQSA-SCPTG--------PPQNPPSSPYCGIVFSGS 1404
PP+QF A Q S P PG A S+ SC P Q PP+SP + S
Sbjct: 75 PPPQQFQA-QSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASP------AAS 127
Query: 1405 SLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQL 1437
S SS + PG + GT + S +L
Sbjct: 128 SSSSFAAVVRYGPGAAAAAGTGGTGSDSASLEL 160
>gi|148762950 BEN domain containing 4 isoform a [Homo sapiens]
Length = 534
Score = 42.0 bits (97), Expect = 0.005
Identities = 48/153 (31%), Positives = 63/153 (41%), Gaps = 25/153 (16%)
Query: 1301 LFKKVSPWETSTSSFFPILAPAVGS-YLPPT------ARAHSPASLSFASYRQVASFGSA 1353
++K+ SP+ S FP PA+ Y PT RA P FA + V+ S
Sbjct: 17 IYKQRSPY--SVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSE 74
Query: 1354 APPRQFDASQFSQGPVPGTCADWIPQSA-SCPTG--------PPQNPPSSPYCGIVFSGS 1404
PP+QF A Q S P PG A S+ SC P Q PP+SP + S
Sbjct: 75 PPPQQFQA-QSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASP------AAS 127
Query: 1405 SLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQL 1437
S SS + PG + GT + S +L
Sbjct: 128 SSSSFAAVVRYGPGAAAAAGTGGTGSDSASLEL 160
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 41.6 bits (96), Expect = 0.007
Identities = 44/153 (28%), Positives = 58/153 (37%), Gaps = 15/153 (9%)
Query: 1315 FFPILAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCA 1374
F P +P V P ++A P SL+ A QV A+PP A+ Q P P
Sbjct: 677 FSPPASPPVSPSATPPSQA--PPSLA-APPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733
Query: 1375 DWIPQSASCPTGPPQNPPSSPYC------GIVFSGSSLSSAQSAPLQHPGGFTTRPSAGT 1428
P PP +PP SP + + L S P P +P
Sbjct: 734 P-----LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788
Query: 1429 FPELDSPQLHFSLPTDPDPIRGFGSYHPSASSP 1461
P L +P L +LP+ P G + PSAS P
Sbjct: 789 PPALATPPLQ-ALPSPPASFPGQAPFSPSASLP 820
Score = 34.3 bits (77), Expect = 1.1
Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 6/213 (2%)
Query: 1292 SCKPTAT-EPLFKKVSPWETSTSSFFPILAPAVGSYLPPTARAHSPASLSFASYRQVASF 1350
S P AT P K P ++ P+ A S T +P S S Q
Sbjct: 300 SSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359
Query: 1351 GSAAPPRQFDASQFSQGPVPGTCADWIP--QSASCPTGPPQNPPSSPYCGIVFSGSSLSS 1408
A PP Q S + IP Q T P P SP + S + +S
Sbjct: 360 PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA--LSSLQATTS 417
Query: 1409 AQSAPLQHPGGFTTRPSAGTFPELDSPQLHFSLPTDPDPIRGFGSYHPSASSPFHFQPSA 1468
S LQ F T T L SP S P D P++ S S P+
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
Query: 1469 ASLTANLRLPMASALPEALCSQSRTTPVDLCLL 1501
+ L++ L + AL +L S S P+ ++
Sbjct: 478 SPLSSPLTIHPLQAL-SSLASHSPQAPLSSLIM 509
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 41.2 bits (95), Expect = 0.009
Identities = 56/252 (22%), Positives = 98/252 (38%), Gaps = 32/252 (12%)
Query: 79 KSIREKRLLDVKNYDPYKPLDITPPPDQKASSSEVKTEGLCPDSATEEEDTVELTEFGMQ 138
+ + E LL V N + L IT + + + K E + A EE +L G
Sbjct: 814 EELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKW 873
Query: 139 NVEIPHLPQDF-----EVAKYNTLEKVGMEGGQEAVVVELQCSRDSRDCPFLISSHFLLD 193
++ + EVA++N E +E +V + + + ++ +
Sbjct: 874 LQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKER---E 930
Query: 194 DGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLREHFTPEATQLASEQLQALLLEEV 253
+ ++ Q + + +D ++ F++ IE+LK+Q + F P E+L ++ E
Sbjct: 931 SDLSSKTQ--LLQDVQDENKLFKSQIEQLKQQNYQQASSFPPH------EELLKVISERE 982
Query: 254 MNSSTLSQEV--------------SDLVEMIW--AEALGHLEHMLLKPVNRISLNDVSKA 297
S L E+ +DL E W EAL E ML VN+ S +
Sbjct: 983 KEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQV 1042
Query: 298 EGILLLVKAALK 309
E + L K LK
Sbjct: 1043 EAVELEAKEVLK 1054
>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
Length = 1313
Score = 40.4 bits (93), Expect = 0.015
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 10/106 (9%)
Query: 598 YQLPDAKTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKY 657
YQ P SSSTK + S ++ ++ A +V N EA +
Sbjct: 22 YQGPPVPASSSTKLLMTSYS----------MRSTVVSRYAHTLVTSVLFNPHAEAHEAIF 71
Query: 658 IFPLDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGA 703
L A + F IN K + E+KEK +A++ Y EA QG A
Sbjct: 72 DLDLPHLAFISNFTMTINNKVYIAEVKEKHQAKKIYEEAHQQGKTA 117
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 40.4 bits (93), Expect = 0.015
Identities = 33/113 (29%), Positives = 46/113 (40%), Gaps = 7/113 (6%)
Query: 1319 LAPAVGSYLP-PTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWI 1377
++P++GS P P AH P S SY Q G +S SQG P C+
Sbjct: 532 MSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP--CSH-- 587
Query: 1378 PQSASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFP 1430
P + P G P P P + S ++LS+ + P G+ T G P
Sbjct: 588 PSPSQGPQGAPY--PFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 40.4 bits (93), Expect = 0.015
Identities = 33/113 (29%), Positives = 46/113 (40%), Gaps = 7/113 (6%)
Query: 1319 LAPAVGSYLP-PTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWI 1377
++P++GS P P AH P S SY Q G +S SQG P C+
Sbjct: 532 MSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP--CSH-- 587
Query: 1378 PQSASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFP 1430
P + P G P P P + S ++LS+ + P G+ T G P
Sbjct: 588 PSPSQGPQGAPY--PFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 40.0 bits (92), Expect = 0.020
Identities = 43/153 (28%), Positives = 53/153 (34%), Gaps = 7/153 (4%)
Query: 1317 PILAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADW 1376
P P + + PP AH P A+ G A PP DA+ + +P
Sbjct: 352 PPKIPKIETTHPPLPPAHPPPD---RKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPA 408
Query: 1377 -IPQSASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSP 1435
+ Q P PP PPSS G+ + S +S LQ T PS G P P
Sbjct: 409 PVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMK-TEGPSYGALPPAYGP 467
Query: 1436 QLHFSLPTDPDPIRGFGSYHPSASSPFHFQPSA 1468
H LP P P P F P A
Sbjct: 468 PAH--LPYHPHVYPPNPPPPPVPPPPASFPPPA 498
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 39.7 bits (91), Expect = 0.026
Identities = 63/240 (26%), Positives = 92/240 (38%), Gaps = 32/240 (13%)
Query: 1308 WETSTSSF-FPILAPA----VGSYLPPTARAHSPASLS----FASYRQVASFGSAAPPRQ 1358
WE S S FP P S P + S SLS F Q G A P Q
Sbjct: 717 WEDSLSPLHFPQFPPQGEDFQSSLQSPVSICSSSTSLSLPQSFPESPQSPPEGPAQSPLQ 776
Query: 1359 FDASQFSQGPVPGTCADWIPQSASCPTGPPQNPPSSPYCGIVF---SGSSLSSAQSAPLQ 1415
S F T A + S P PP+ P SP V S +S S +QS+P+
Sbjct: 777 RPVSSFFSY----TLASLLQSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQSSPVS 832
Query: 1416 HPGGFTTRPSAGTFPE--LDSPQLHFSLPTDPDPIRGFGSYHPSASSPF-HFQPSAASLT 1472
T+ + + PE L SP + FS T P + +SSP + S+ +L
Sbjct: 833 SFPSSTSSSLSKSSPESPLQSPVISFSSSTSLSP------FSEESSSPVDEYTSSSDTLL 886
Query: 1473 ANLRLPMASALPEALCSQSRTTPVDLCLLEESVGSLEGSRCPVFAFQSSDTESDELSEVL 1532
+ L + +L E + P+ L+E V L + + T+++ L+ V+
Sbjct: 887 ESDSLTDSESLIE-------SEPLFTYTLDEKVDELARFLLLKYQVKQPITKAEMLTNVI 939
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 38.5 bits (88), Expect = 0.057
Identities = 44/140 (31%), Positives = 58/140 (41%), Gaps = 22/140 (15%)
Query: 1328 PPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWI-PQSASCPTG 1386
PP RA++P + + S AP + P+P T + P P
Sbjct: 181 PPGRRANAPPT-------PLPMHSSKAPAYN------REKPLPPTPGQRLHPGREGPPAP 227
Query: 1387 PPQNPPSSPY-CGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGT---FPELDSPQLHFSLP 1442
PP PP SP SG SL+ P + P G PS+ T PEL PQ H SL
Sbjct: 228 PPVKPPPSPVNIRTGPSGQSLAPPPP-PYRQPPGVPNGPSSPTNESAPEL--PQRHNSLH 284
Query: 1443 TD-PDPIRGFGSYHPSASSP 1461
P P+RG P+++SP
Sbjct: 285 RKTPGPVRGLAPPPPTSASP 304
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 37.7 bits (86), Expect = 0.097
Identities = 48/168 (28%), Positives = 61/168 (36%), Gaps = 22/168 (13%)
Query: 1319 LAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIP 1378
+ PA S P T + +P A+ V GS + + Q PVP T P
Sbjct: 193 VTPAPSSAPPGTPQLPTPGPTPSAT--AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 250
Query: 1379 QSASCPTGPPQ-NPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQL 1437
A P PP +PP P + PLQ G +PSA P P L
Sbjct: 251 --ALHPQRPPSPHPPPHP-------------SPHPPLQPLTGSAGQPSA---PSHAQPPL 292
Query: 1438 HFSLPTDPDPIR-GFGSYHPSASSPFHFQPSAASLTANLRLPMASALP 1484
H P P ++ G HP PF P A+ A L A+A P
Sbjct: 293 HGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 37.7 bits (86), Expect = 0.097
Identities = 48/168 (28%), Positives = 61/168 (36%), Gaps = 22/168 (13%)
Query: 1319 LAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIP 1378
+ PA S P T + +P A+ V GS + + Q PVP T P
Sbjct: 747 VTPAPSSAPPGTPQLPTPGPTPSAT--AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 804
Query: 1379 QSASCPTGPPQ-NPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQL 1437
A P PP +PP P + PLQ G +PSA P P L
Sbjct: 805 --ALHPQRPPSPHPPPHP-------------SPHPPLQPLTGSAGQPSA---PSHAQPPL 846
Query: 1438 HFSLPTDPDPIR-GFGSYHPSASSPFHFQPSAASLTANLRLPMASALP 1484
H P P ++ G HP PF P A+ A L A+A P
Sbjct: 847 HGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 37.7 bits (86), Expect = 0.097
Identities = 48/168 (28%), Positives = 61/168 (36%), Gaps = 22/168 (13%)
Query: 1319 LAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIP 1378
+ PA S P T + +P A+ V GS + + Q PVP T P
Sbjct: 747 VTPAPSSAPPGTPQLPTPGPTPSAT--AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 804
Query: 1379 QSASCPTGPPQ-NPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQL 1437
A P PP +PP P + PLQ G +PSA P P L
Sbjct: 805 --ALHPQRPPSPHPPPHP-------------SPHPPLQPLTGSAGQPSA---PSHAQPPL 846
Query: 1438 HFSLPTDPDPIR-GFGSYHPSASSPFHFQPSAASLTANLRLPMASALP 1484
H P P ++ G HP PF P A+ A L A+A P
Sbjct: 847 HGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,099,268
Number of Sequences: 37866
Number of extensions: 3192081
Number of successful extensions: 10521
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 142
Number of HSP's that attempted gapping in prelim test: 10215
Number of HSP's gapped (non-prelim): 390
length of query: 1724
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1608
effective length of database: 13,855,062
effective search space: 22278939696
effective search space used: 22278939696
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.