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Search of human proteins with 112789541
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo
sapiens]
(250 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 490 e-139
gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] 483 e-137
gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens] 478 e-135
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 471 e-133
gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens] 325 2e-89
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens] 321 3e-88
gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens] 311 4e-85
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 300 6e-82
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 300 6e-82
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 297 7e-81
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 295 2e-80
gi|148746195 trichohyalin [Homo sapiens] 77 1e-14
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 69 5e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 67 1e-11
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 66 2e-11
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 66 3e-11
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 65 4e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 64 1e-10
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 63 2e-10
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 63 2e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 63 2e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 4e-10
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 62 6e-10
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 62 6e-10
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 61 8e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 61 8e-10
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 60 1e-09
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 60 2e-09
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 59 3e-09
gi|4506467 radixin [Homo sapiens] 59 4e-09
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 490 bits (1262), Expect = e-139
Identities = 250/250 (100%), Positives = 250/250 (100%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
Query: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARR 120
MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARR
Sbjct: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARR 120
Query: 121 EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNI 180
EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNI
Sbjct: 121 EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNI 180
Query: 181 DHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGTP 240
DHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGTP
Sbjct: 181 DHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGTP 240
Query: 241 AKGKVGGRWK 250
AKGKVGGRWK
Sbjct: 241 AKGKVGGRWK 250
>gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
Length = 258
Score = 483 bits (1243), Expect = e-137
Identities = 250/258 (96%), Positives = 250/258 (96%), Gaps = 8/258 (3%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQE--------EEKPRPKLTAPKIPEGEKVDFDDIQ 52
MSDEEVEQVEEQYEEEEEAQEEEEVQE EEKPRPKLTAPKIPEGEKVDFDDIQ
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
Query: 53 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 112
KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR
Sbjct: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 120
Query: 113 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 172
LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA
Sbjct: 121 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
Query: 173 ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 232
ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK
Sbjct: 181 ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 240
Query: 233 HSKKAGTPAKGKVGGRWK 250
HSKKAGTPAKGKVGGRWK
Sbjct: 241 HSKKAGTPAKGKVGGRWK 258
>gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens]
Length = 256
Score = 478 bits (1229), Expect = e-135
Identities = 249/256 (97%), Positives = 249/256 (97%), Gaps = 6/256 (2%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEE-----EEVQE-EEKPRPKLTAPKIPEGEKVDFDDIQKK 54
MSDEEVEQVEEQYEEEEEAQEE EEV E EEKPRPKLTAPKIPEGEKVDFDDIQKK
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK 60
Query: 55 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 114
RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA
Sbjct: 61 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 120
Query: 115 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 174
EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER
Sbjct: 121 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
Query: 175 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 234
RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS
Sbjct: 181 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 240
Query: 235 KKAGTPAKGKVGGRWK 250
KKAGTPAKGKVGGRWK
Sbjct: 241 KKAGTPAKGKVGGRWK 256
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 471 bits (1213), Expect = e-133
Identities = 240/250 (96%), Positives = 243/250 (97%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
Query: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARR 120
MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARR
Sbjct: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARR 120
Query: 121 EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNI 180
EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNI
Sbjct: 121 EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNI 180
Query: 181 DHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGTP 240
DHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDI +R+R+ K SKKAGTP
Sbjct: 181 DHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIMNVRARVQMLAKFSKKAGTP 240
Query: 241 AKGKVGGRWK 250
AKGKVGGRWK
Sbjct: 241 AKGKVGGRWK 250
>gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens]
Length = 251
Score = 325 bits (833), Expect = 2e-89
Identities = 166/254 (65%), Positives = 203/254 (79%), Gaps = 7/254 (2%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPR----PKLTAPKIPEGEKVDFDDIQKKRQ 56
MSD E ++ EE+ EEE A+EEEE +E KP P L PKIPEGE+VDFDDI +KR
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRM 60
Query: 57 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EKERERQ +LAEE
Sbjct: 61 EKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEE 120
Query: 117 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 176
K R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT REMK +IL+ER+K
Sbjct: 121 KMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKK 180
Query: 177 PLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
PL+ID++GE++LR+KA+EL + +HQLE +KF+ KLK+QKY+I L +RI AQK K
Sbjct: 181 PLDIDYMGEEQLREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKG 240
Query: 237 AGTPAKGKVGGRWK 250
AG KG+VGGRWK
Sbjct: 241 AG---KGRVGGRWK 251
>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
Length = 262
Score = 321 bits (823), Expect = 3e-88
Identities = 168/265 (63%), Positives = 205/265 (77%), Gaps = 18/265 (6%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKP-------RPK--------LTAPKIPEGEK 45
MSD E ++ EE+ EEE A+EEEE EE +P RPK L PKIPEGE+
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
Query: 46 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 105
VDFDDI +KR KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EK
Sbjct: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
Query: 106 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 165
ERERQ +LAEEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT RE
Sbjct: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
Query: 166 MKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRS 225
MK +IL+ER+KPL+ID++GE++LR+KA+EL + +HQLE +KF+ KLK+QKY+I L +
Sbjct: 181 MKVRILSERKKPLDIDYMGEEQLREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYN 240
Query: 226 RIDQAQKHSKKAGTPAKGKVGGRWK 250
RI AQK K AG KG+VGGRWK
Sbjct: 241 RISHAQKFRKGAG---KGRVGGRWK 262
>gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]
Length = 278
Score = 311 bits (796), Expect = 4e-85
Identities = 168/281 (59%), Positives = 205/281 (72%), Gaps = 34/281 (12%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKP-------RPK--------LTAPKIPEGEK 45
MSD E ++ EE+ EEE A+EEEE EE +P RPK L PKIPEGE+
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
Query: 46 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 105
VDFDDI +KR KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EK
Sbjct: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
Query: 106 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 165
ERERQ +LAEEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT RE
Sbjct: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
Query: 166 MKKKILAERRKPLNIDHLGEDKL----------------RDKAKELWETLHQLEIDKFEF 209
MK +IL+ER+KPL+ID++GE++L R+KA+EL + +HQLE +KF+
Sbjct: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
Query: 210 GEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 250
KLK+QKY+I L +RI AQK K AG KG+VGGRWK
Sbjct: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAG---KGRVGGRWK 278
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 300 bits (769), Expect = 6e-82
Identities = 155/254 (61%), Positives = 197/254 (77%), Gaps = 9/254 (3%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPK-----LTAPKIPEGEKVDFDDIQKKRQ 56
++ E + EE EEEE + E+ EE KP+P+ L PKIP+GE+VDFDDI +KR
Sbjct: 36 AETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRM 95
Query: 57 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR E+E+ERQNRLAEE
Sbjct: 96 EKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEE 155
Query: 117 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 176
+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ K ++K GK+QT RE KKKILAERRK
Sbjct: 156 RARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKTERKSGKRQTEREKKKKILAERRK 214
Query: 177 PLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I LR+RI+ QK SK
Sbjct: 215 VLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKT 274
Query: 237 AGTPAKGKVGGRWK 250
G K KV GRWK
Sbjct: 275 RG---KAKVTGRWK 285
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 300 bits (769), Expect = 6e-82
Identities = 155/254 (61%), Positives = 197/254 (77%), Gaps = 9/254 (3%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPK-----LTAPKIPEGEKVDFDDIQKKRQ 56
++ E + EE EEEE + E+ EE KP+P+ L PKIP+GE+VDFDDI +KR
Sbjct: 46 AETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRM 105
Query: 57 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR E+E+ERQNRLAEE
Sbjct: 106 EKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEE 165
Query: 117 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 176
+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ K ++K GK+QT RE KKKILAERRK
Sbjct: 166 RARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKTERKSGKRQTEREKKKKILAERRK 224
Query: 177 PLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I LR+RI+ QK SK
Sbjct: 225 VLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKT 284
Query: 237 AGTPAKGKVGGRWK 250
G K KV GRWK
Sbjct: 285 RG---KAKVTGRWK 295
Score = 32.7 bits (73), Expect = 0.30
Identities = 17/71 (23%), Positives = 35/71 (49%)
Query: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAK 126
I+ E ++EE+E A++E + R E +++ + E E + + EEE+AK
Sbjct: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAK 63
Query: 127 RRAEDDLKKKK 137
+ +++ K
Sbjct: 64 EAEDGPMEESK 74
Score = 32.0 bits (71), Expect = 0.52
Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
Query: 84 LKERIEKRRAERAEQQRIRAEKE----RERQNRLAEEKARREEEDAKRRAEDDLKKKKA 138
++E +E+ E E+ + E++ + Q AEE A E E + RAE+D ++++A
Sbjct: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 297 bits (760), Expect = 7e-81
Identities = 156/256 (60%), Positives = 198/256 (77%), Gaps = 11/256 (4%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPK-----LTAPKIPEGEKVDFDDIQKKRQ 56
++ E + EE EEEE + E+ EE KP+P+ L PKIP+GE+VDFDDI +KR
Sbjct: 31 AETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRM 90
Query: 57 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR E+E+ERQNRLAEE
Sbjct: 91 EKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEE 150
Query: 117 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKA--DQKRGKKQTAREMKKKILAER 174
+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ KA ++K GK+QT RE KKKILAER
Sbjct: 151 RARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKAQTERKSGKRQTEREKKKKILAER 209
Query: 175 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 234
RK L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I LR+RI+ QK S
Sbjct: 210 RKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVS 269
Query: 235 KKAGTPAKGKVGGRWK 250
K G K KV GRWK
Sbjct: 270 KTRG---KAKVTGRWK 282
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 295 bits (756), Expect = 2e-80
Identities = 155/257 (60%), Positives = 198/257 (77%), Gaps = 12/257 (4%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPK-----LTAPKIPEGEKVDFDDIQKKRQ 56
++ E + EE EEEE + E+ EE KP+P+ L PKIP+GE+VDFDDI +KR
Sbjct: 36 AETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRM 95
Query: 57 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR E+E+ERQNRLAEE
Sbjct: 96 EKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEE 155
Query: 117 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYL---AKADQKRGKKQTAREMKKKILAE 173
+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ A+ ++K GK+QT RE KKKILAE
Sbjct: 156 RARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKQAQTERKSGKRQTEREKKKKILAE 214
Query: 174 RRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKH 233
RRK L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I LR+RI+ QK
Sbjct: 215 RRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKV 274
Query: 234 SKKAGTPAKGKVGGRWK 250
SK G K KV GRWK
Sbjct: 275 SKTRG---KAKVTGRWK 288
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 77.0 bits (188), Expect = 1e-14
Identities = 59/233 (25%), Positives = 120/233 (51%), Gaps = 12/233 (5%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
E V + EE+ +EEE Q + E+QEEE+ KL E +++ + ++++Q + L
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL------ERQELRRERQEEEQQQQRLRRE 303
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEE 123
Q L E R++++EE +ER E++ R +Q R E+ RE+Q R +E+ RRE++
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 124 DAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHL 183
+R E++ ++++ L + Q R ++Q RE + + + R+ +
Sbjct: 364 -LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR- 421
Query: 184 GEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
E +LR +E E H+ + ++ ++LKR++ + R ++ ++H ++
Sbjct: 422 -EQQLR---REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470
Score = 72.8 bits (177), Expect = 3e-13
Identities = 67/251 (26%), Positives = 122/251 (48%), Gaps = 31/251 (12%)
Query: 7 EQVEEQYEEEEEAQEEEEV---QEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
+++E QY +EEE Q+EEE +E EK R + + E E++ ++ Q R+ ++
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERERQNRLAEE-KARRE 121
Q L + E + ++EE L+E EKRR + E+Q R E ++E + L EE + RR+
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
Query: 122 EEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQK------------------RGKK-QT 162
E + + R E++L+++K Y ++D K +G++ +
Sbjct: 1194 ERERQYREEEELQRQKRKQ----RYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQ 1249
Query: 163 AREMKKKILAERRKPLNIDH-LGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIT 221
R+++ L +R+ ++ H LGE + RD+ +E Q F E+L+R++
Sbjct: 1250 FRQLEDSQLRDRQSQQDLQHLLGEQQERDREQE--RRRWQQRDRHFPEEEQLEREEQKEA 1307
Query: 222 TLRSRIDQAQK 232
R R Q +K
Sbjct: 1308 KRRDRKSQEEK 1318
Score = 65.5 bits (158), Expect = 4e-11
Identities = 56/226 (24%), Positives = 116/226 (51%), Gaps = 15/226 (6%)
Query: 7 EQVEEQYEEEEEAQEEEEV---QEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
++ E++Y EEEE Q+EEE +E EK R + + + +++ ++ Q R+ ++ L
Sbjct: 984 QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL 1043
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERERQNRLAE--EKARR 120
Q + E + ++EE L E E RR + E+Q R E ++E + L E EK RR
Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR 1103
Query: 121 EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE-----RR 175
+E + + R E++L++++ + +++ +++ ++ ++++L E RR
Sbjct: 1104 QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR 1163
Query: 176 KPLNIDHLGEDKLRDKAKEL----WETLHQLEIDKFEFGEKLKRQK 217
+ L + E++L+ + ++L E Q ++ E+L+RQK
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Score = 58.9 bits (141), Expect = 4e-09
Identities = 56/223 (25%), Positives = 115/223 (51%), Gaps = 16/223 (7%)
Query: 7 EQVEEQYEE--EEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQ 64
EQ EE++E+ E+E +E+ +E+E+ R L + E + + Q KR ++ +
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 65 ALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEED 124
L E R+++E L+ E+RR +R ++Q E+ER +Q +E++ RRE+E+
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQE---EEERLQQRLRSEQQLRREQEE 544
Query: 125 -----AKRRAEDDL---KKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 176
KR E L ++++ L L K +++R +++ RE +++ L +R K
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEER-LEQRLK 603
Query: 177 PLNIDHLGEDKLRDK--AKELWETLHQLEIDKFEFGEKLKRQK 217
++ L +++ R++ +E E + ++ K E E+ ++Q+
Sbjct: 604 REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Score = 58.2 bits (139), Expect = 7e-09
Identities = 45/197 (22%), Positives = 104/197 (52%), Gaps = 8/197 (4%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
EQ+ ++ + +E +EE + +E EK R + + E E++ ++ Q R+ ++ Q
Sbjct: 897 EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER 956
Query: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERERQNRLAE--EKARREEE 123
+ + +K +++E L E EKRR + E++ R E ++E + L E EK RR+E
Sbjct: 957 ERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW 1016
Query: 124 DAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE-----RRKPL 178
+ + R +D+L++++ L + +++ +++ ++ ++++L E RR+ L
Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076
Query: 179 NIDHLGEDKLRDKAKEL 195
+ E++L+ + ++L
Sbjct: 1077 ERQYRKEEELQQEEEQL 1093
Score = 57.8 bits (138), Expect = 9e-09
Identities = 51/242 (21%), Positives = 116/242 (47%), Gaps = 19/242 (7%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME---- 62
E+ E++E+E Q+ + QEEE+ L + E+ + + Q +R+ ++ E
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK 520
Query: 63 -------LQALIDSHFEARKKEEEELVALKERIEKRRAER-AEQQRIRAEKERERQNRLA 114
LQ + S + R+++EE L +R E++R E+ +QR++ E+E R L
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580
Query: 115 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 174
E+ RR++ KR E+ L+++ L + +Q+ +++ E ++++L
Sbjct: 581 REEERRQQR-LKREQEERLEQR--LKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
Query: 175 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 234
+ + + +LR + +E E + E ++ ++LKR+ + + ++ Q+ +
Sbjct: 638 EQ----EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693
Query: 235 KK 236
++
Sbjct: 694 RE 695
Score = 57.8 bits (138), Expect = 9e-09
Identities = 42/196 (21%), Positives = 101/196 (51%), Gaps = 7/196 (3%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEV---QEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
E+ E+ E+Q E+E + E+ + +EEE+ + +L + + E+ + + KR+ +
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
Query: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARR 120
+E + +++ ++L+ +E ++R +R +++R+ +RE RL +E+ R
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEE--R 615
Query: 121 EEEDAKRRAEDDLKKKKALSS--MGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPL 178
E+ KR ++ ++++ L S L + Q+R +++ RE +++ L +R K
Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Query: 179 NIDHLGEDKLRDKAKE 194
+ + E +L ++ +E
Sbjct: 676 HEEERREQELAEEEQE 691
Score = 57.0 bits (136), Expect = 2e-08
Identities = 50/238 (21%), Positives = 115/238 (48%), Gaps = 17/238 (7%)
Query: 7 EQVEEQYEEEEEAQEEEEV---QEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
++ E QY EEE+ Q+EEE +E EK R + + + +K+ + Q + +
Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERERQNRLAEEKARR-- 120
Q + E + ++EE L+E EKRR + E+Q R + E ++E + L EE+ +R
Sbjct: 984 QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL 1043
Query: 121 EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNI 180
+E + + R E++L++++ L + + R +++ R+ +K+ ++ + +
Sbjct: 1044 QERERQYREEEELQQEE---------EQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094
Query: 181 DHLGEDKLRDKAKELWETLHQLEIDKFEF--GEKLKRQKYDITTLRSRIDQAQKHSKK 236
E + R + + +L+ ++ + E+ KR++ ++ ++ Q+ ++
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ 1152
Score = 56.6 bits (135), Expect = 2e-08
Identities = 52/217 (23%), Positives = 112/217 (51%), Gaps = 19/217 (8%)
Query: 7 EQVEEQYEEEEEAQEEEEV---QEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
++ E QY ++++ Q++EE +E EK R + K E E++ ++ Q R+ ++
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERERQNRLAEEK--ARR 120
Q + + + ++EE L+E EKRR + E+Q R E ++E + L EE+ RR
Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Query: 121 EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNI 180
+E + + R E++L++++ L + +KR +++ R+ +++ E +
Sbjct: 1074 QELERQYRKEEELQQEE---------EQLLREEPEKRRRQERERQCREE---EELQQEEE 1121
Query: 181 DHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 217
L E++ + + +EL E ++ E + + E+L R++
Sbjct: 1122 QLLREEREKRRRQEL-ERQYREEEEVQQEEEQLLREE 1157
Score = 55.8 bits (133), Expect = 3e-08
Identities = 51/209 (24%), Positives = 100/209 (47%), Gaps = 31/209 (14%)
Query: 7 EQVEEQYEEEEEAQEEEEV---QEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
++ E QY +++E Q+EEE +E EK R + + E E++ ++ Q + ++
Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAE-------------RAEQQRIRAEKERERQ 110
Q L + + + ++EE L+E EKRR + + E+Q +R E+E+ R+
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
Query: 111 NRLA-----EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 165
L EE+ ++EEE R E + ++++ L Y + + ++ ++Q RE
Sbjct: 1134 QELERQYREEEEVQQEEEQLLRE-EPEKRRRQELE------RQYREEEELQQEEEQLLRE 1186
Query: 166 MKKKILAERRKPLNIDHLGEDKLRDKAKE 194
++K ER + + E+ R K K+
Sbjct: 1187 EQEKRRQERERQYREE---EELQRQKRKQ 1212
Score = 55.5 bits (132), Expect = 4e-08
Identities = 53/235 (22%), Positives = 112/235 (47%), Gaps = 35/235 (14%)
Query: 10 EEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK---------DL 60
E+Q E++ + E++++ E++ R + + E E+ + Q++R+ + D
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Query: 61 MELQALIDSHFEARKKEE----------EELVALKERIEKRRAERAEQQRIRAEKERERQ 110
++ + + H + R+K++ E + L+E + + ER EQQ +R E+E R+
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ-LRREQEERRE 516
Query: 111 NRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 170
RL R+EEE+ R + L+ ++ L L K ++++ +Q RE + K
Sbjct: 517 QRL----KRQEEEE---RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 171 LAERRKPLNIDHLGEDK----LRDKAKELWETLHQLEIDKFEFGE----KLKRQK 217
E R+ + E + R++ + L + L + E+++ E E +LKR++
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
Score = 54.7 bits (130), Expect = 7e-08
Identities = 49/236 (20%), Positives = 120/236 (50%), Gaps = 17/236 (7%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
+Q EE+ E++EE +E++E +E+++ R + + E + + Q +R+ ++ Q L
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERR----EQQLRREQEEERREQQL 364
Query: 67 IDSHFEARKKEE---EELVALKERIEKRRAERAEQQ-----RIRAEKE--RERQNRLAEE 116
E R++++ E+ + ++++ + + R EQQ ++R E++ RE+Q R ++
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424
Query: 117 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 176
R +EE+ + + ++++ L +L + ++ +Q R+ + K E +
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER 484
Query: 177 PLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 232
L E++ R++ + + L + + ++ E ++LKRQ+ + L+ R+ Q+
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERRE--QRLKRQEEE-ERLQQRLRSEQQ 537
Score = 53.5 bits (127), Expect = 2e-07
Identities = 52/228 (22%), Positives = 110/228 (48%), Gaps = 16/228 (7%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRP-KLTAPKIPEGEKVDFDDIQK----KR 55
+ + E +Q+ Q + + +EE++++ +E+ R + + E E+ ++ Q+ +R
Sbjct: 1470 LQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQR 1529
Query: 56 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE 115
Q K L E Q L +++++ + +E E+ R ER EQQ R +ER+R+ RL E
Sbjct: 1530 QRKFLQEEQQLRRQERGQQRRQDRDRKFREE--EQLRQEREEQQLSR--QERDRKFRLEE 1585
Query: 116 EKARREEEDAK-RRAEDDLKKKKALSSMGANYSSYLAKAD---QKRGKKQTAREMKKKIL 171
+K RR+E++ K E L++++ + + + Q+R ++Q R+ + +
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
Query: 172 AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYD 219
E L + D+ ++ E L+ + ++L+RQ+ D
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE---EQQLRRQERD 1690
Score = 53.1 bits (126), Expect = 2e-07
Identities = 48/209 (22%), Positives = 105/209 (50%), Gaps = 22/209 (10%)
Query: 3 DEEVEQVEEQYEEEEEAQ-EEEEVQ-------EEEKPRPKLTAPKIPEGEKVDFDDIQKK 54
DEE+ + ++++E EE + EEE++Q EE +L ++ E + ++ Q++
Sbjct: 170 DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ 229
Query: 55 RQNKDLMELQALIDSHFEAR----KKEEEELV--------ALKERIEK-RRAERAEQQRI 101
R+ + Q + + R +KEEE+L L+E E+ R+ ER E +R
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 102 RAEKERERQNRLAEEKARREEEDAKRRAEDDLK-KKKALSSMGANYSSYLAKADQKRGKK 160
R E+E+++Q E++ RR++E+ +R +++ + +++ L + ++R ++
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
Query: 161 QTAREMKKKILAERRKPLNIDHLGEDKLR 189
Q RE +++ ++ + + E +LR
Sbjct: 350 QLRREQEEERREQQLRREQEEERREQQLR 378
Score = 53.1 bits (126), Expect = 2e-07
Identities = 51/262 (19%), Positives = 130/262 (49%), Gaps = 30/262 (11%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQ---------EEEKPRPKLTA---PKIPEGEKVDFDDI 51
+++++ E+ +E++E + +E + EEE+ R + T P + E + + +
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
Query: 52 QKKRQNKDLMELQALIDSHFEARKKEEEEL-----VALKERIEKRRAERAEQQRIRAEKE 106
Q++ + E + E + +EEE+L L+E EKRR + E+Q + +K
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 107 RERQNRL---AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA 163
++++ +L EK RR+E + K R E++L++++ + +++ KK
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 164 REMKKKILAERRKPLNI-----DHLGEDKLRDKAKELW----ETLHQLEIDKFEFGEKLK 214
++ ++++L E R+ + + E++L+ + ++L ET + E+++ ++ ++ +
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER-QYRKEEE 1085
Query: 215 RQKYDITTLRSRIDQAQKHSKK 236
Q+ + LR ++ ++ ++
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERE 1107
Score = 52.8 bits (125), Expect = 3e-07
Identities = 60/260 (23%), Positives = 121/260 (46%), Gaps = 49/260 (18%)
Query: 3 DEEVEQVEEQYEEEEEAQEE---------EEVQEEEKPRPKLTAPKIPEGEKVDFDDIQ- 52
+E+ Q+E+ + ++Q++ E +E+E+ R + PE E+++ ++ +
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
Query: 53 -KKRQNKDLMELQALIDSHFEARKK--------EEEELVALKERIEKRRAER-------- 95
K+R K E Q L + E R++ EEE+L+ +E RR ER
Sbjct: 1307 AKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366
Query: 96 -----------AEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGA 144
E+QR+R + ERER+ E++ R +E + + R + D K ++ +
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQ-ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
Query: 145 NYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDH---LGEDKLRDKAKELWETLHQ 201
+ ++++ ++Q E ++K L E ++ H E++L + +E + LH+
Sbjct: 1426 QERDRKFREEEQQVRRQ---ERERKFLEEEQQLRQERHRKFREEEQLLQEREE--QQLHR 1480
Query: 202 LEIDK--FEFGEKLKRQKYD 219
E D+ E ++L+RQ+ D
Sbjct: 1481 QERDRKFLEEEQQLRRQERD 1500
Score = 52.4 bits (124), Expect = 4e-07
Identities = 60/236 (25%), Positives = 111/236 (47%), Gaps = 23/236 (9%)
Query: 10 EEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDS 69
EEQ +E E Q+ + + K R + + E E+ +D Q+ R+ + +L+ D
Sbjct: 1560 EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619
Query: 70 HFE-----ARKKEEEEL-------VALKERIEKRRAERAEQQR-IRAEKERERQNRL--- 113
F +++EE++L L+E + RR ER +Q R R K RE + L
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG 1679
Query: 114 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQK---RGKKQTAREMKKKI 170
E++ RR+E D K R E+ +++ L + + + R ++Q +E +++
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739
Query: 171 LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSR 226
L + + I L E++LR + +E + L + E D+ E+ RQ+ + LRS+
Sbjct: 1740 LRRQERYRKI--LEEEQLRPEREE--QQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Score = 50.8 bits (120), Expect = 1e-06
Identities = 38/183 (20%), Positives = 88/183 (48%), Gaps = 7/183 (3%)
Query: 15 EEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEAR 74
EEE Q+ + ++EE+ +L ++ E+ + + + KR+ + Q L+ S +
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Query: 75 KKEEEELVALKERIEKRRAERAEQQRIRAEKERE-RQNRLAEEKARREEEDAKRRAEDDL 133
+++++ +ER E+R E++R+ +RE + R +E A E+E A+ R + +
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Query: 134 KK--KKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDK 191
K + S A S ++ ++ G+++ + +K+ RR+ + E++ +
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR----RRRESELQWQEEERAHRQ 757
Query: 192 AKE 194
+E
Sbjct: 758 QQE 760
Score = 50.4 bits (119), Expect = 1e-06
Identities = 43/175 (24%), Positives = 86/175 (49%), Gaps = 13/175 (7%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLM 61
S++++ + +E+ E+ +EEE+ E+E+ +L K + E+ D + K+ + +
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRL---KREQEER--RDQLLKREEERRQQ 588
Query: 62 ELQALIDSHFEAR-KKEEEELVALKERIEKR------RAERAEQQRIRAEKERERQNRLA 114
L+ + E R K+EE E + +ER E+R ER +Q E+E RQ +L
Sbjct: 589 RLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLR 648
Query: 115 EEKARREEEDAKRRAEDD-LKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKK 168
E+ R E+ KR E++ L+++ LA+ +Q++ +++ + K
Sbjct: 649 REQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPK 703
Score = 50.1 bits (118), Expect = 2e-06
Identities = 46/156 (29%), Positives = 84/156 (53%), Gaps = 23/156 (14%)
Query: 5 EVEQVEEQYEEEEEAQEEE--EVQEEEKPRPKLTAPKIPEGEK-VDFDDIQKKRQNKDLM 61
E EQ+ ++ E+E+ ++E ++ EEE+ RP+ ++ E+ F + ++ RQ ++
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Query: 62 ELQAL-IDSHF----EARKKEEEELVALKERIEKRRAE----RAEQQRIRAEKERERQNR 112
+L++ D F + R++ EE+ + ++R K R E + E+Q R +ER+RQ R
Sbjct: 1787 QLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR 1846
Query: 113 LAE-----EKARRE------EEDAKRRAEDDLKKKK 137
E EK+RRE EE+ KRR E + K ++
Sbjct: 1847 AEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Score = 49.7 bits (117), Expect = 2e-06
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 16/204 (7%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
E +EQ + Q +EE ++ +E QE E+ R + + +G + + +++ + ++L+EL
Sbjct: 159 ERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLEL 218
Query: 64 QALIDSHFEARKKEEEELVALKE------------RIEKRRAERAEQQRIRAEKERERQN 111
+ + +++E ++ V +E R E+ + + E QR R +E E Q
Sbjct: 219 RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 112 RLAE----EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMK 167
R E + R+EEE ++R + + ++ + ++R +++ RE +
Sbjct: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ 338
Query: 168 KKILAERRKPLNIDHLGEDKLRDK 191
+ E R+ + E++ R++
Sbjct: 339 LRREQEERREQQLRREQEEERREQ 362
Score = 49.7 bits (117), Expect = 2e-06
Identities = 52/235 (22%), Positives = 111/235 (47%), Gaps = 31/235 (13%)
Query: 7 EQVEEQYEEEEEAQEEEE-VQEEEKPRPKLTAPKIPEGE---KVDFDDIQKKRQNKDLME 62
EQ E Q EE Q E+ + EEE+ + + E E + + +Q++ + + L E
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851
Query: 63 LQALIDSHFEARKKEEEE-----LVALKERIEKRR----AERAEQQRIRAE-----KERE 108
+ + E R+ +E+ L+E ++RR A+ A Q+++R E +E E
Sbjct: 852 EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
Query: 109 RQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKK 168
R EK RR+E++ + R E+ L++++ L + +KR +++ R+ +K
Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEE---------EQLLREEREKRRRQERERQYRK 962
Query: 169 KILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDK----FEFGEKLKRQKYD 219
++++ + E + R + ++ + +L+ ++ E EK +RQ+++
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE 1017
Score = 49.3 bits (116), Expect = 3e-06
Identities = 39/202 (19%), Positives = 97/202 (48%), Gaps = 11/202 (5%)
Query: 4 EEVEQVEEQYEEEEEAQEE----EEVQEEEKPRPKLTA-PKIPEGEKVDFDDIQKKRQNK 58
+E E+ Q +EEE+ ++ + ++ E+ R +L+A P + E + +++++ +
Sbjct: 749 QEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQ 808
Query: 59 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKA 118
+ + + R++ E+EL L+E + +R ERA+Q + + +E Q R ++
Sbjct: 809 RFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868
Query: 119 RREE------EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 172
RR++ E+ ++R L K AL L + +++ +++ + +++
Sbjct: 869 RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER 928
Query: 173 ERRKPLNIDHLGEDKLRDKAKE 194
+ R+ + E LR++ ++
Sbjct: 929 QYREEEQLQQEEEQLLREEREK 950
Score = 48.9 bits (115), Expect = 4e-06
Identities = 63/248 (25%), Positives = 107/248 (43%), Gaps = 46/248 (18%)
Query: 7 EQVEEQYEEEEEAQEEEEVQE--EEKPRPKLTAPKIPEGEKVDFDD-------------- 50
++ E QY EEEE Q ++ Q +E R L PE E D+
Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 51 -----IQKKRQNKDLMEL---QALIDSHFEARK--------KEEEELVALKERIEKRRAE 94
++ ++ +DL L Q D E R+ EEE+L +++ KRR
Sbjct: 1253 LEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR 1312
Query: 95 RA--EQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAK 152
++ E+Q +R E+E +R+ + + K R EE+ + R E L++++ +
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH--- 1369
Query: 153 ADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKF-EFGE 211
Q++G+K E + + RK L E +LR + +E + L Q KF E +
Sbjct: 1370 --QEQGRKFLEEEQRLRRQERERKFLK----EEQQLRCQERE--QQLRQDRDRKFREEEQ 1421
Query: 212 KLKRQKYD 219
+L RQ+ D
Sbjct: 1422 QLSRQERD 1429
Score = 46.2 bits (108), Expect = 3e-05
Identities = 45/201 (22%), Positives = 93/201 (46%), Gaps = 31/201 (15%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQ---------EEEKPRPKLTAPKIPEGEKVDFDDIQKK 54
EE +Q+ Q E + QEE++++ EEE+ R + ++ E+ + I ++
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER--YRKILEE 1752
Query: 55 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER----AEQQRIRAEKE---- 106
Q + E Q L + + +EEE+L +E + R E E++++R E+E
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQL 1812
Query: 107 ----RERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQT 162
R+ + R EE+ + EE++ + R E D + + + + +R +++
Sbjct: 1813 RPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE--------EQFATQEKSRREEQEL 1864
Query: 163 AREMKKKILAERRKPLNIDHL 183
+E ++K ER + L +H+
Sbjct: 1865 WQEEEQKRRQERERKLREEHI 1885
Score = 46.2 bits (108), Expect = 3e-05
Identities = 41/143 (28%), Positives = 73/143 (51%), Gaps = 13/143 (9%)
Query: 5 EVEQVEEQYEEEEEAQEEEE--VQEEEKPRPKLTAPKIPEGEKV-DFDDIQKKRQNKDLM 61
E EQ+ + EE++ ++E + +EEE+ R + ++ E F + ++ RQ +
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER--- 1807
Query: 62 ELQALIDSHFEARKKEEEELVALKERIEKRRAER-----AEQQRIRAEKERERQNRL--A 114
E Q L + + + EEE + L+E+ ++ R ER AE+Q EK R + L
Sbjct: 1808 EEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQE 1867
Query: 115 EEKARREEEDAKRRAEDDLKKKK 137
EE+ RR+E + K R E +++K
Sbjct: 1868 EEQKRRQERERKLREEHIRRQQK 1890
Score = 45.4 bits (106), Expect = 5e-05
Identities = 46/224 (20%), Positives = 102/224 (45%), Gaps = 21/224 (9%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
E++ Q + + +EE+ ++ +E+ R L + ++ + +++ R K E Q L
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQERE-QQLRQDRDRKFREEEQQL 1423
Query: 67 IDSHFEARKKEEEELVALKERIEK-----------RRAERAEQQRIRAEKERERQNRLAE 115
+ + +EEE+ V +ER K R + E++++ E+E ++ +R
Sbjct: 1424 SRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQER 1483
Query: 116 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERR 175
++ EEE RR E D K ++ +L + ++Q R+ +++ +
Sbjct: 1484 DRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE------EQQLHRQQRQRKFLQEE 1537
Query: 176 KPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYD 219
+ L G+ + +D+ ++ E QL ++ E ++L RQ+ D
Sbjct: 1538 QQLRRQERGQQRRQDRDRKFREE-EQLRQEREE--QQLSRQERD 1578
Score = 44.3 bits (103), Expect = 1e-04
Identities = 50/266 (18%), Positives = 115/266 (43%), Gaps = 49/266 (18%)
Query: 3 DEEVEQVEEQYEEE-EEAQEEEEVQEEEKPRPK-------------------------LT 36
+EE E++E++ + E EE + E+E+ EEE+ + + +
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Query: 37 APKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKE-----------EEELVALK 85
P+ EG++ + +K+R+ + ++ Q +H + +++E EE+ +
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 86 ERIEKR-----------RAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLK 134
+R+ R RAE +Q+ R E E + + ++ RE+E E+ L+
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 135 KKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKE 194
+++ + +++R ++Q + + L E RK + L+++ ++
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901
Query: 195 LWETLHQLEID-KFEFGEKLKRQKYD 219
+ L + E + + E EK +RQ+ +
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQE 927
Score = 43.1 bits (100), Expect = 2e-04
Identities = 39/205 (19%), Positives = 91/205 (44%), Gaps = 28/205 (13%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
+ D E+ + ++E + EEE Q + R + ++ EGE+ + Q++ + +D
Sbjct: 110 LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQER-ELAEGEEQS--EKQERLEQRD- 165
Query: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARR 120
R++ +EEL ++ ++R RAE++++++ K E + EE+ RR
Sbjct: 166 -------------RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRR 212
Query: 121 -----------EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 169
EE+ +RR D ++ + L K ++K +++ R+ + +
Sbjct: 213 RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272
Query: 170 ILAERRKPLNIDHLGEDKLRDKAKE 194
E+ + L L ++ ++ ++
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQ 297
Score = 42.7 bits (99), Expect = 3e-04
Identities = 58/249 (23%), Positives = 109/249 (43%), Gaps = 44/249 (17%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
EEVE++E+ EE +E+ +EE + + K E E+ +++++Q + L
Sbjct: 605 EEVERLEQ-----EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRL 659
Query: 64 ----------QALIDSHFEARKKE---EEELVALKERIEKR------------------- 91
Q L H E R+++ EEE +ERI+ R
Sbjct: 660 KREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKV 719
Query: 92 --RAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSY 149
R + E QR R E+E +R+ R E +EEE A R+ +++ +++ A S
Sbjct: 720 YSRPRKQEGQRRRQEQEEKRRRR-ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKS- 777
Query: 150 LAKADQKRGKKQTAREMKKKIL-AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFE 208
+ Q+ + RE +++ L AE R+ L E++ +++ + + E+ E
Sbjct: 778 -ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR-QRREREKELQFLE 835
Query: 209 FGEKLKRQK 217
E+L+R++
Sbjct: 836 EEEQLQRRE 844
Score = 42.7 bits (99), Expect = 3e-04
Identities = 33/140 (23%), Positives = 72/140 (51%), Gaps = 13/140 (9%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQ---EEEKPRPKLTAPKIPEGEKV--DFDDIQKKRQNK 58
E EQ + E + + +EEE+++ EE++ R + + K E E++ + ++ Q + Q +
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Query: 59 D----LMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER----ERQ 110
D E Q ++ + ++E + +E+ + R E+Q + E+E+ ER+
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE 1877
Query: 111 NRLAEEKARREEEDAKRRAE 130
+L EE RR++++ +R +
Sbjct: 1878 RKLREEHIRRQQKEEQRHRQ 1897
Score = 42.0 bits (97), Expect = 5e-04
Identities = 56/228 (24%), Positives = 107/228 (46%), Gaps = 23/228 (10%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEV--QEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLM 61
EE +++ Q E + +EE+++ QE E+ + K E E+ + ++ +++
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ----QLSRQERDRKFR 1433
Query: 62 ELQALIDSHFEARKKEEEELVALKERIEKRRAE------RAEQQRIRAEKERERQNRLAE 115
E + + RK EEE +ER K R E R EQQ R E++R + E
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR----KFLE 1489
Query: 116 E--KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 173
E + RR+E D K R E +L+ ++ + Q++ ++ + +++ +
Sbjct: 1490 EEQQLRRQERDRKFR-EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
Query: 174 RRKPLNIDHLGEDKLRDKAKELWETLHQLEID-KFEFGE-KLKRQKYD 219
RR+ + E++LR + +E + L + E D KF E K++RQ+ +
Sbjct: 1549 RRQDRDRKFREEEQLRQEREE--QQLSRQERDRKFRLEEQKVRRQEQE 1594
Score = 38.5 bits (88), Expect = 0.006
Identities = 35/128 (27%), Positives = 66/128 (51%), Gaps = 11/128 (8%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQ---EEEKPRPKLTAPKIP-EGEKVDFDDIQKK-R 55
+ E EQ E + + +EEE+++ EE++ RP+ K E E++ ++ +++ R
Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Query: 56 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER----AEQQRIRAEKERERQN 111
Q +D + E ++EE+EL +E +KRR ER E+ R +KE +R
Sbjct: 1839 QERDRQYRAEEQFATQEKSRREEQEL--WQEEEQKRRQERERKLREEHIRRQQKEEQRHR 1896
Query: 112 RLAEEKAR 119
++ E K++
Sbjct: 1897 QVGEIKSQ 1904
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 68.6 bits (166), Expect = 5e-12
Identities = 56/234 (23%), Positives = 117/234 (50%), Gaps = 15/234 (6%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
+S EE +Q EE+ + +E E+++EE+K R + ++ E+ + K Q+K +
Sbjct: 233 ISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEER----ERIKAEQDKKI 288
Query: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER--ERQNRLAEEKA 118
+ +A I++ +A +E E + E+R R E++R E++R E + R AEE+
Sbjct: 289 ADERARIEAEEKAAAQERE-----RREAEERERMREEEKRAAEERQRIKEEEKRAAEERQ 343
Query: 119 RREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPL 178
R +EE+ KR AE+ + K+ A A+A+++ K + + + K L E++ +
Sbjct: 344 RIKEEE-KRAAEERQRIKE--EEKRAAEERQRARAEEEE-KAKVEEQKRNKQLEEKKHAM 399
Query: 179 NIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 232
+ +K+ K + W + + DK + K+ + T ++++ ++ Q+
Sbjct: 400 QETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQE 453
Score = 54.7 bits (130), Expect = 7e-08
Identities = 62/246 (25%), Positives = 106/246 (43%), Gaps = 26/246 (10%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQK-KRQNKDLME 62
E E+ Q E EA+E E ++EEEK R +I E EK ++ Q+ K + K E
Sbjct: 296 EAEEKAAAQERERREAEERERMREEEK-RAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 354
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREE 122
E ++ +EEE K E+R+ RAE++ +E++R +L E+K +E
Sbjct: 355 ---------ERQRIKEEE----KRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE 401
Query: 123 EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDH 182
K + + K ++ A +K+G+ E K+ A+R K
Sbjct: 402 TKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGE-----EKGTKVQAKREK------ 450
Query: 183 LGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAK 242
L EDK K +E+ + + + + E + +K T ++S+ + H K
Sbjct: 451 LQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTF 510
Query: 243 GKVGGR 248
+ GGR
Sbjct: 511 SRPGGR 516
Score = 50.1 bits (118), Expect = 2e-06
Identities = 32/101 (31%), Positives = 60/101 (59%), Gaps = 6/101 (5%)
Query: 37 APKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERA 96
AP++ G++++ +++++R + E + L EA + EE LK++ E+RR
Sbjct: 527 APQVEAGKRLE--ELRRRRGETESEEFEKLKQKQQEAALELEE----LKKKREERRKVLE 580
Query: 97 EQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKK 137
E+++ R ++E +R+ R EEK R +EE +RRAE K++K
Sbjct: 581 EEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 621
Score = 45.1 bits (105), Expect = 6e-05
Identities = 46/257 (17%), Positives = 113/257 (43%), Gaps = 30/257 (11%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
+ +EE EE+ E +E+ +V+E+++ + + K+ + +++K + K +
Sbjct: 359 IKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWV 418
Query: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARR 120
E +A D A K++ E EK +A++++++ +K ++ + +EK ++
Sbjct: 419 NEKKAQEDKLQTAVLKKQGE--------EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 470
Query: 121 EEEDAKRRAEDDLKKKKALSSMGANYSSYL-----------------AKADQKRGKKQTA 163
++E K + + +KK + + + ++ A D K +
Sbjct: 471 DKE-PKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQ 529
Query: 164 REMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFE----FGEKLKRQKYD 219
E K++ RR+ + +KL+ K +E L +L+ + E E+ +R+K +
Sbjct: 530 VEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE 589
Query: 220 ITTLRSRIDQAQKHSKK 236
+ R ++ ++ K+
Sbjct: 590 EADRKLREEEEKRRLKE 606
Score = 44.7 bits (104), Expect = 8e-05
Identities = 47/254 (18%), Positives = 109/254 (42%), Gaps = 27/254 (10%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLM 61
+D + E+ E+ E QE E++E E + E+ +D +K+ + ++
Sbjct: 139 NDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKP 198
Query: 62 ELQALIDSHFEA-------RKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 114
+ ++ ++ E +EE +++LK + E++R + E ++
Sbjct: 199 KRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKME 258
Query: 115 EE-KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 173
EE K R E E A+ AE+ + K A+ D+K ++ E ++K A+
Sbjct: 259 EEDKERAEAERARLEAEERERIK--------------AEQDKKIADERARIEAEEKAAAQ 304
Query: 174 RRKPLNIDHLGEDKLRDKAKELWETLHQLEIDK---FEFGEKLKRQKYDITTLRSRIDQA 230
R+ + +++R++ K E +++ ++ E +++K ++ R RI +
Sbjct: 305 ERERREAEE--RERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEE 362
Query: 231 QKHSKKAGTPAKGK 244
+K + + A+ +
Sbjct: 363 EKRAAEERQRARAE 376
Score = 44.7 bits (104), Expect = 8e-05
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 25/134 (18%)
Query: 42 EGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRI 101
E E +F+ +++K+Q L EL+ E +KK EE L+E ++R+ E A++ ++
Sbjct: 545 ETESEEFEKLKQKQQEAAL-ELE-------ELKKKREERRKVLEEEEQRRKQEEADR-KL 595
Query: 102 RAEKERERQNRLAEEKARREEEDAKRRAE-------DDLKKKKALSSMGANY-----SSY 149
R E+E+ RL EE RR E A++R + DD K K + G++ + +
Sbjct: 596 REEEEK---RRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEF 652
Query: 150 LAKADQK-RGKKQT 162
L K+ QK G K T
Sbjct: 653 LNKSVQKSSGVKST 666
Score = 37.0 bits (84), Expect = 0.016
Identities = 41/199 (20%), Positives = 85/199 (42%), Gaps = 27/199 (13%)
Query: 72 EARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARRE--------EE 123
E R+++ EE+ ERI +R + E++ R + R RQ RL +++ E
Sbjct: 9 ELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEV 68
Query: 124 DAKRRAEDDLKKKKALSSM-----GANYSSYLAKADQKRGKK-QTAREMKKKI------- 170
+A+ D+ K ++ A + LA+ +++R K+ Q A E +K+
Sbjct: 69 NAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDA 128
Query: 171 ---LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRI 227
L RR + E++ +K ++ + EI++ E K ++ ++
Sbjct: 129 SLSLPSRRMQ---NDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKK 185
Query: 228 DQAQKHSKKAGTPAKGKVG 246
+ +K ++ P +G +G
Sbjct: 186 EDKEKEEEEEEKPKRGSIG 204
Score = 32.0 bits (71), Expect = 0.52
Identities = 18/58 (31%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Query: 86 ERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMG 143
ER + R ++ E+ R+ AE+ ++N EE+A RE +R ++ L++K+ S+G
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERR--RRARQERLRQKQEEESLG 60
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 67.0 bits (162), Expect = 1e-11
Identities = 48/233 (20%), Positives = 122/233 (52%), Gaps = 8/233 (3%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
EQ +E E+E+E +E++E++E+E+ + + EK+ + + RQ + L E +
Sbjct: 325 EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384
Query: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRI--RAEKERERQNRLAEEKARREEED 124
+ + + +EE + ER+ ++ EQ+++ + EK RE + +EK R++E+
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444
Query: 125 AKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLG 184
K + E+ +++++ M + + ++ + +++ E ++K ++R P + L
Sbjct: 445 -KMQEEERIRERE--KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 501
Query: 185 E-DKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
E +K++++ +++WE ++ + +G++ K + + +R + DQ + +K
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE--KMREQEDQMWEQEEK 552
Score = 63.2 bits (152), Expect = 2e-10
Identities = 47/237 (19%), Positives = 120/237 (50%), Gaps = 24/237 (10%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
DE + + EE+ E+E+ E+ E EEK K+ E EK D +K ++ + + E
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMREEK--------KMQEQEKKTRDQEEKMQEEERIRE 454
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER-ERQNRLAEEKARRE 121
+ + E +++EE++ +E + ++ + +QQR+ +KE+ Q ++ E++ +
Sbjct: 455 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514
Query: 122 EEDAKRRAEDDL--KKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLN 179
E++ K R ++++ ++KK + + ++ R ++ E ++K+ + +K +
Sbjct: 515 EQEEKIRDQEEMWGQEKK------------MWRQEKMREQEDQMWEQEEKMRDQEQKMWD 562
Query: 180 IDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
+ E K +++ K+ W+ ++ ++ E+ K+ + + +R + ++ Q+ +K
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMR-EEERMREREKKMREEEEMMREQEEKMQEQEEK 618
Score = 62.4 bits (150), Expect = 4e-10
Identities = 45/220 (20%), Positives = 119/220 (54%), Gaps = 15/220 (6%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
M + EQ ++ +++EE+ +EEE ++E EK K+ E E++ + +K ++ ++
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREK--------KMREEEEMMREQEEKMQEQEEK 618
Query: 61 M-ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKAR 119
M E + + E +++EE++ +E++ ++ + EQQR+ +KE+ ++ +E+ +
Sbjct: 619 MQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 678
Query: 120 REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLN 179
+E++ K ++ ++KK + + + R +++ RE +++++ E+ + +
Sbjct: 679 MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMRE-EEEMMREQEEKMQ 737
Query: 180 IDHLGEDKLRDKAKELWETLHQL--EIDKFEFGEKLKRQK 217
E+K++++ +E+WE ++ + +K ++L QK
Sbjct: 738 EQ---EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Score = 58.5 bits (140), Expect = 5e-09
Identities = 46/222 (20%), Positives = 115/222 (51%), Gaps = 6/222 (2%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKK-RQNKDLM- 61
E++++ E+ E+EE+ E+E+++++ + + K T + E+ + +KK R+ +++M
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 62 ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARRE 121
E + + E +++EEE+ +E++ ++ + EQQR+ +KE+ ++ +E+ +
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 122 EEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNID 181
E++ K R +++ K + M + ++ G+++ ++K+ + K +
Sbjct: 791 EQEEKMRDQEE-KMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQE 849
Query: 182 HLGEDKLR---DKAKELWETLHQLEIDKFEFGEKLKRQKYDI 220
E+K++ +K +E E + E E EK++ Q+ I
Sbjct: 850 EKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 58.2 bits (139), Expect = 7e-09
Identities = 46/216 (21%), Positives = 107/216 (49%), Gaps = 15/216 (6%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
E++ + E+ E+E+ ++EE++ E+EK K E EK +D +K R+ + + E
Sbjct: 665 EKLWEHEKMQEQEKMQEQEEKIWEQEK-----MEKKTQEQEKKTWDQ-EKMREEESMRER 718
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERE--RQNRLAEEKARRE 121
+ + E +++EE++ +E+++++ E EQ+ E+E + Q RL E+K +
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 778
Query: 122 EEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNID 181
E + + E ++++ M + ++ RG+++ R ++K+ + K
Sbjct: 779 EHEKMQEQEKIWEQEE---KMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWG-- 833
Query: 182 HLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 217
E+K+ + +++W ++E EK++ Q+
Sbjct: 834 --QEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQE 867
Score = 57.8 bits (138), Expect = 9e-09
Identities = 45/198 (22%), Positives = 99/198 (50%), Gaps = 12/198 (6%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
+Q E+ + +EE +E+E E++ + ++ E EK + ++ R+ K+L E +
Sbjct: 290 KQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQ 349
Query: 67 IDSHFEARKKEEEELVALKERI---EKRRAERAEQQRIRAEKERERQNRLAEEKAR-REE 122
+ E ++EE++ +E++ E+R E+ +Q R + +K R+++ R+ E+ R RE+
Sbjct: 350 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409
Query: 123 EDAKRRAE---DDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLN 179
E+ R E + ++K + M ++K +++ RE +KK+ E
Sbjct: 410 EERMREQEKMWEQVEKMREEKKM-QEQEKKTRDQEEKMQEEERIREREKKMREEEETMRE 468
Query: 180 IDHLGEDKLRDKAKELWE 197
E+K++ + + +WE
Sbjct: 469 ----QEEKMQKQEENMWE 482
Score = 57.8 bits (138), Expect = 9e-09
Identities = 44/230 (19%), Positives = 115/230 (50%), Gaps = 28/230 (12%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
EQ ++ +E+EE+ +++E+ +++ R + K E EK +D +K R+ + + E +
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERME---KKTQEQEKKTWDQEEKMREEERMREREKK 597
Query: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAK 126
+ E +++EE++ +E+++++ + EQ+ EK +E++ ++ E++ + E++ K
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE----EKMQEQEEKMWEQEEKMWEQEEK 653
Query: 127 RRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGED 186
+ L ++K +K +++ +E ++KI + + E
Sbjct: 654 MWEQQRLPEQKE-----------KLWEHEKMQEQEKMQEQEEKIWEQEKM--------EK 694
Query: 187 KLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
K +++ K+ W+ E + EK R++ ++ +R + ++ Q+ +K
Sbjct: 695 KTQEQEKKTWDQEKMREEESMREREKKMREEEEM--MREQEEKMQEQEEK 742
Score = 56.6 bits (135), Expect = 2e-08
Identities = 47/204 (23%), Positives = 104/204 (50%), Gaps = 22/204 (10%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQE------EEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 57
EE E + EQ EE+ ++EE++QE E++ + + K+ E E+ ++ +K +
Sbjct: 600 EEEEMMREQ--EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 58 KDLMELQALIDSH----FEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 113
+ L E + + H + + +E+EE + +E++EK+ E+ E++ EK RE ++
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ-EKKTWDQEKMREEESMR 716
Query: 114 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 173
EK REEE+ R E+ +++++ + ++ +++ E ++K+ +
Sbjct: 717 EREKKMREEEEMMREQEEKMQEQE---------EKMQEQEEEMWEQEEKMWEQEEKMWEQ 767
Query: 174 RRKPLNIDHLGEDKLRDKAKELWE 197
+R P + L E + + +++WE
Sbjct: 768 QRLPEQKEKLWEHEKMQEQEKIWE 791
Score = 53.5 bits (127), Expect = 2e-07
Identities = 44/205 (21%), Positives = 107/205 (52%), Gaps = 25/205 (12%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
EQ E+ +E+E+ ++EE++ E+E+ KI + E++ + + RQ K + E +
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEE--------KIRDQEEMWGQEKKMWRQEK-MREQEDQ 545
Query: 67 IDSHFEARKKEEEELVALKERIEKRRAERA------EQQRIRAEKERERQNRLAEEKAR- 119
+ E + +E+++ +ER+EK+ E+ E++ E+ RER+ ++ EE+
Sbjct: 546 MWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605
Query: 120 REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLN 179
RE+E+ + E+ +++++ M + ++ +++ E ++K+ ++R P
Sbjct: 606 REQEEKMQEQEEKMQEQE--EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663
Query: 180 IDHLGE-------DKLRDKAKELWE 197
+ L E +K++++ +++WE
Sbjct: 664 KEKLWEHEKMQEQEKMQEQEEKIWE 688
Score = 52.4 bits (124), Expect = 4e-07
Identities = 52/237 (21%), Positives = 112/237 (47%), Gaps = 19/237 (8%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGE-KVDFDDIQKKRQNKD 59
+ +E Q EE E+E++ +++EE ++ R + K+ E E K+ + + + Q K+
Sbjct: 270 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKE 329
Query: 60 LMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER----ERQNRLAE 115
L E + + E R++EE+ ++ E+ R +++++ ++ER E+Q R E
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389
Query: 116 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERR 175
+K R +EE R E D + ++ M + + KK +E K + E+
Sbjct: 390 QKMRDQEE---RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM 446
Query: 176 KPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 232
+ E+++R++ K++ E + E EK+++Q+ ++ + Q Q+
Sbjct: 447 QE-------EERIREREKKMREEEETMR----EQEEKMQKQEENMWEQEEKEWQQQR 492
Score = 49.7 bits (117), Expect = 2e-06
Identities = 49/215 (22%), Positives = 101/215 (46%), Gaps = 25/215 (11%)
Query: 10 EEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDS 69
EE ++ E QE+ + E EK +L ++++K + + Q ++
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVK-----------ELKRKLERAKFLLPQVQTNT 269
Query: 70 HFEARKKEEEELVALKERIEKRRAER-AEQQRIRAE--KERERQNRL-AEEKARREEEDA 125
E ++EEEL +++I K+ + +++R+R + K RE++ ++ +EK RE+E
Sbjct: 270 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKE 329
Query: 126 KRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE---MKKKILAERRKPLNIDH 182
R E +L+++K L K ++ K + E +++ L E+ K +
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ- 388
Query: 183 LGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 217
E K+RD+ + +WE +L E E+++ Q+
Sbjct: 389 --EQKMRDQEERMWEQDERLR----EKEERMREQE 417
Score = 49.7 bits (117), Expect = 2e-06
Identities = 51/229 (22%), Positives = 114/229 (49%), Gaps = 15/229 (6%)
Query: 8 QVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKV-DFDDIQKKRQNKDLMELQAL 66
QV+ +EE ++EEE++E+EK K + E++ + + ++++ K + + L
Sbjct: 264 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRL 323
Query: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAK 126
+ E R++E+E L+E+ E R E Q++ E+E + R EEK R+EE
Sbjct: 324 REQEKELREQEKE----LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE--- 376
Query: 127 RRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGED 186
R E + + ++ M + ++ R K++ RE +K + E+ + + E
Sbjct: 377 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK--MWEQVEKMR----EEK 430
Query: 187 KLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSK 235
K++++ K+ + +++ ++ E+ K+ + + T+R + ++ QK +
Sbjct: 431 KMQEQEKKTRDQEEKMQ-EEERIREREKKMREEEETMREQEEKMQKQEE 478
Score = 42.4 bits (98), Expect = 4e-04
Identities = 29/149 (19%), Positives = 78/149 (52%), Gaps = 14/149 (9%)
Query: 3 DEEVEQVEEQYEEEEE---AQEEEEVQEEEKPRPKLTAP----------KIPEGEKVDFD 49
+E++++ EE+ +E+EE QEE+ ++EEK + P K+ E EK+
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQ 792
Query: 50 DIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER-AEQQRIRAEKERE 108
+ + + Q + + + + E + +EE++ +E++ + + +++++ ++E+
Sbjct: 793 EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM 852
Query: 109 RQNRLAEEKARREEEDAKRRAEDDLKKKK 137
+ +E+ RE+E+ R E+ +++++
Sbjct: 853 EEKMQGQEEKMREQEEKMRGQEEKMREQE 881
Score = 42.4 bits (98), Expect = 4e-04
Identities = 34/150 (22%), Positives = 73/150 (48%), Gaps = 9/150 (6%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAP-----KIPEGEKVDFDDIQKKRQNKDLM 61
EQ EE +E+EE+ E+EE E++ P+ K+ E EK+ + + + Q + +
Sbjct: 745 EQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMR 804
Query: 62 ELQALIDSHFEARKKEEEELVALKERI--EKRRAERAEQQRIRAEKERERQNRLAEEKAR 119
+ + E + +EE++ +E++ ++ + E++ E++ E + + EEK R
Sbjct: 805 GQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMR 864
Query: 120 REEEDAKRRAEDDLKKKKALSSMGANYSSY 149
+EE K R +++ +++ G Y
Sbjct: 865 EQEE--KMRGQEEKMREQEEKMRGQEEKIY 892
Score = 40.8 bits (94), Expect = 0.001
Identities = 31/177 (17%), Positives = 86/177 (48%), Gaps = 14/177 (7%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+EE+ + +E+ +E+E + +E+ +E + K+ + E+ + ++K + M+
Sbjct: 725 EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 784
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER---ERQNRLAEEKAR 119
Q I E + +EE++ +E++ R +++++R ++E+ + + +E+
Sbjct: 785 EQEKIWEQEEKMRDQEEKMRGQEEKM------RGQEEKMRGQEEKMWGQEEKMWGQEEKM 838
Query: 120 REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 176
+E+ E+ +++K M + ++ RG+++ RE ++K+ + K
Sbjct: 839 WGQEEKMWGQEEKMEEK-----MQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 35.0 bits (79), Expect = 0.061
Identities = 39/199 (19%), Positives = 88/199 (44%), Gaps = 23/199 (11%)
Query: 54 KRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 113
K++N +L E L +S E+ + L + KR+ ERA+ + + ++
Sbjct: 224 KKKNAELQEKLPLAES--------EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMW 275
Query: 114 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 173
+E+ RE+E R+ E+ + +++ L + + K +++ ++K L E
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQE----------ERLREQEGKMREQEEKMWRQEKRLRE 325
Query: 174 RRKPLNIDHLGEDKLRD--KAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 231
+ K L E +LR+ + +E E + + E +E EK++ Q+ + R+ + +
Sbjct: 326 QEKELREQ---EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 382
Query: 232 KHSKKAGTPAKGKVGGRWK 250
K ++ + + W+
Sbjct: 383 KQMREQEQKMRDQEERMWE 401
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 66.2 bits (160), Expect = 2e-11
Identities = 52/237 (21%), Positives = 116/237 (48%), Gaps = 12/237 (5%)
Query: 7 EQVEEQYEEEEEAQ-EEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQA 65
EQ E+ E+EE+ Q +EE++ E+E+ K + E+V + Q ++Q + + + +
Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE 262
Query: 66 LIDSHFEARKKEEEELVALKERI--EKRRAERAEQQRIRAE--KERERQNRLAEEKARRE 121
+ E +++EE+++ KE+ E++ E+ EQ R + E +E+E Q R EE+ R +
Sbjct: 263 QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQ 322
Query: 122 EEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNID 181
EE ++ E ++K+ + + ++ + Q E +K + RK
Sbjct: 323 EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ---- 378
Query: 182 HLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAG 238
E+++R + +++ + Q+ K + GE+ ++ + + + +Q +K + G
Sbjct: 379 ---EEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMG 432
Score = 60.8 bits (146), Expect = 1e-09
Identities = 45/197 (22%), Positives = 95/197 (48%), Gaps = 20/197 (10%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPE--------GEKVDFDDIQKK 54
+E+V++ EEQ ++EE E+E Q E+ L + E E++ + Q +
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 55 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 114
Q + + E + + E K+EE++ KE++ +++ + +Q+ E+E + Q +
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ-- 364
Query: 115 EEKARREEEDAKRRAEDDLKK----KKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 170
EE+ R++EE +++ E K+ +K MG + +Q R +++ E K+++
Sbjct: 365 EEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQM 424
Query: 171 LAERRKPLNIDHLGEDK 187
+ +H+GE K
Sbjct: 425 RKQE------EHMGEQK 435
Score = 57.0 bits (136), Expect = 2e-08
Identities = 48/241 (19%), Positives = 117/241 (48%), Gaps = 21/241 (8%)
Query: 4 EEVEQVEEQY----EEEEEAQEEEEVQEEEKPRPKLTAPKIPEGE-KVDFDDIQKKRQNK 58
E+ QV EQ E+E + +E+E E++ + + ++ E E ++ + Q Q +
Sbjct: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213
Query: 59 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKA 118
+ + + + E +K+EE++ +E+++K+ + +Q E Q R EE+
Sbjct: 214 QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQ---------EEQMRKQEEQM 264
Query: 119 RREEEDAKRRAEDDLKKKKAL---SSMGANYSSYLAKADQKRGKKQTAREMKKKILAERR 175
R +EE + + E LK+K+ G + +Q R +++ RE +++ + E+
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ-MREQE 323
Query: 176 KPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSK 235
+ + E+++ ++ +++WE Q+ + + GE+ ++ + +R + +Q +K +
Sbjct: 324 EQMGKQ---EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEE 380
Query: 236 K 236
+
Sbjct: 381 Q 381
Score = 42.0 bits (97), Expect = 5e-04
Identities = 30/126 (23%), Positives = 66/126 (52%), Gaps = 12/126 (9%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
EQ E+ ++EE+ E++E E+K + ++ E E+ Q ++Q + + + +
Sbjct: 321 EQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEE------QMQKQEEQVRKQEEQ 374
Query: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEK--ARREEED 124
+ E +K+EE++ + E++ E+ EQ + E+ RE++ ++ E+K R++EE
Sbjct: 375 MRKQEEQMRKQEEQM----RKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
Query: 125 AKRRAE 130
+ E
Sbjct: 431 MGEQKE 436
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 65.9 bits (159), Expect = 3e-11
Identities = 54/213 (25%), Positives = 101/213 (47%), Gaps = 21/213 (9%)
Query: 5 EVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQ 64
E++ V + + Q E E ++E + R K + E ++ +KKR+ ++ + +
Sbjct: 16 ELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKER 75
Query: 65 ALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEED 124
E ++KE E K + EK++ ER ++ R +K++ER+ R E K RRE +
Sbjct: 76 ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
Query: 125 AKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLG 184
KRR + K++ K +++RGK++ R+ +KK E+++ N
Sbjct: 136 KKRRKKKRRKER---------------KREKERGKRERKRKKRKKEEREKKRERN----- 175
Query: 185 EDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 217
K R K +E E + + K E +K +R+K
Sbjct: 176 -RKERKKERERKERRERKKERKKERRKKKERKK 207
Score = 57.4 bits (137), Expect = 1e-08
Identities = 44/174 (25%), Positives = 87/174 (50%), Gaps = 11/174 (6%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
+E + E++ E E+ ++ E ++E+K R K K E ++ + + +K+R+ K+ +
Sbjct: 38 KERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKR 97
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKAR-REE 122
+ E +K+E ++ + + +K R ER + + R E++R+++ + K R RE+
Sbjct: 98 KK------EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
Query: 123 EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 176
E KR + K+KK K +K +++ RE KK+ ERRK
Sbjct: 152 ERGKR----ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Score = 52.4 bits (124), Expect = 4e-07
Identities = 47/163 (28%), Positives = 80/163 (49%), Gaps = 23/163 (14%)
Query: 74 RKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDL 133
++K E E +ER +K + +R +++R + E+ER+R+ R + K RRE+E KR+ E
Sbjct: 45 KRKREREKERKRERGKKEKKKRKKRERGK-ERERKRKEREKQRKERREKERRKRKKE--- 100
Query: 134 KKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAK 193
KKK+ G + ++K+ K++ RE + K ER++ K R K K
Sbjct: 101 KKKRERKQRG--------RRERKKKKERKERERENKQRRERKR----------KKRRKKK 142
Query: 194 ELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
E + E K E K KR+K + R R + +K ++
Sbjct: 143 RRKERKREKERGKRERKRK-KRKKEEREKKRERNRKERKKERE 184
Score = 52.4 bits (124), Expect = 4e-07
Identities = 36/136 (26%), Positives = 70/136 (51%), Gaps = 9/136 (6%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
E +Q +E+ E+E +++E+ + E K R + K E + +++R+NK E
Sbjct: 81 EREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK-------ERERENKQRRER 133
Query: 64 QALIDSHFEARK--KEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARRE 121
+ + RK K E+E + + +KR+ E E++R R KER+++ E + R++
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193
Query: 122 EEDAKRRAEDDLKKKK 137
E +RR + + KK +
Sbjct: 194 ERKKERRKKKERKKDR 209
Score = 37.4 bits (85), Expect = 0.012
Identities = 27/103 (26%), Positives = 56/103 (54%), Gaps = 7/103 (6%)
Query: 10 EEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFD--DIQKKRQNKDLMELQALI 67
E + ++E + +E E Q E+ R K K + K + + ++KR+ + E +
Sbjct: 113 ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR 172
Query: 68 DSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQ 110
+ + + RKKE E KER E+++ ER +++R + E++++R+
Sbjct: 173 ERNRKERKKERER----KERRERKK-ERKKERRKKKERKKDRK 210
Score = 36.6 bits (83), Expect = 0.021
Identities = 26/133 (19%), Positives = 60/133 (45%)
Query: 104 EKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA 163
E ER+++ R E++ R E++ KR KKK+ G + +++R +++
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 164 REMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTL 223
K+K ++R+ K +++ + E + E + + +K +R++
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
Query: 224 RSRIDQAQKHSKK 236
R + ++ +K KK
Sbjct: 153 RGKRERKRKKRKK 165
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 65.5 bits (158), Expect = 4e-11
Identities = 50/223 (22%), Positives = 111/223 (49%), Gaps = 22/223 (9%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
EQ +E E+E+E +E+++++E+E+ + + EK+ + + RQ + L E +
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRI--RAEKERERQNRLAEEKARREEED 124
+ + + +EE + ER+ ++ EQ+++ + EK +E + EK REEE+
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406
Query: 125 AKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHL- 183
R E+ ++K++ + + ++K ++Q E K+K+ + + + +
Sbjct: 407 TMREQEEKMQKQE----------ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 184 -GEDKLRD------KAKELW--ETLHQLEIDKFEFGEKLKRQK 217
E+K+RD + K++W E + + E +E EK++ Q+
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
Score = 63.9 bits (154), Expect = 1e-10
Identities = 47/245 (19%), Positives = 125/245 (51%), Gaps = 17/245 (6%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
+Q E+ + +EE +E+E E++ + + ++ E EK + ++ R+ K L E +
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQ 311
Query: 67 IDSHFEARKKEEEELVALKERI--------EKRRAERAEQQRIRAEKER--ERQNRLAEE 116
+ E ++EE++ +E++ E+ + R ++Q++R ++ER E+ RL E+
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 371
Query: 117 KARREEEDAKRRAEDDLKKKKAL----SSMGANYSSYLAKADQKRGKKQTAREMKKKILA 172
+ R E++ E+ +++++ + M + + ++ + +++ E ++K
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 431
Query: 173 ERRKPLNIDHLGE-DKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 231
++R P + L E +K++++ +++WE ++ + +G++ K + + +R + DQ
Sbjct: 432 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE--KMREQEDQMW 489
Query: 232 KHSKK 236
+ +K
Sbjct: 490 EQEEK 494
Score = 59.7 bits (143), Expect = 2e-09
Identities = 46/236 (19%), Positives = 116/236 (49%), Gaps = 16/236 (6%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
EQ E+ +E+EE+ +++EE+ +EK K+ EK+ + Q Q + + + +
Sbjct: 450 EQEEKIWEQEEKIRDQEEMWGQEK--------KMWRQEKMREQEDQMWEQEEKMRDQEQK 501
Query: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA---EEKARREE- 122
+ E +++E L +ER+ +++ +++++R EK+ + Q + EEK R EE
Sbjct: 502 MWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER 561
Query: 123 --EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNI 180
E K+ E++ ++ M + ++ +++ +E ++K+ + K
Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 621
Query: 181 DHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
+ EDK++++ + +WE +++ + + E+ ++ + +R + ++ Q +K
Sbjct: 622 EE--EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675
Score = 57.4 bits (137), Expect = 1e-08
Identities = 40/205 (19%), Positives = 102/205 (49%), Gaps = 10/205 (4%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
EQ ++ +++EE+ +EEE ++E EK + + EK+ + + + Q + + E +
Sbjct: 544 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603
Query: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAK 126
+ E ++EE++ +E E + E+ E + EK +E++ ++ E++ + E++ K
Sbjct: 604 MQEQEEKMWEQEEKMWEQEE--EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 661
Query: 127 RRAEDDL------KKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNI 180
R +++ K ++ M + ++ RG+++ ++K+ + K
Sbjct: 662 MREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQ 721
Query: 181 DHL--GEDKLRDKAKELWETLHQLE 203
+ + E+++RD+ +++ E L + E
Sbjct: 722 EEMREKEERIRDQKEKMQERLPEHE 746
Score = 56.6 bits (135), Expect = 2e-08
Identities = 50/242 (20%), Positives = 117/242 (48%), Gaps = 32/242 (13%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+E + + E+ +E+EE+ QEEE ++E EK K+ E E+ + +K ++ ++ M
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIREREK--------KMREEEETMREQEEKMQKQEENMW 423
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRI--RAEKERERQNRLAEEK--- 117
Q E ++ +++ L KE++ ++ + ++++I + EK R+++ +EK
Sbjct: 424 EQ-------EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 476
Query: 118 ---ARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 174
RE+ED E+ ++ ++ M + ++ R K++ RE KK E
Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQE--QKMWDQEERMWEQDERLREKEERMREQKKMWQQEE 534
Query: 175 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 234
+ E K +++ K+ W+ ++ ++ E+ K+ + + +R + ++ Q+
Sbjct: 535 KM------REEKKTQEQEKKTWDQEEKMR-EEERMREREKKMREEEEMMREQEEKMQEQE 587
Query: 235 KK 236
+K
Sbjct: 588 EK 589
Score = 53.5 bits (127), Expect = 2e-07
Identities = 49/262 (18%), Positives = 128/262 (48%), Gaps = 32/262 (12%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEV---------QEEEKPRPKLTAPKIPEGEKVDFDDIQK 53
++++ EE+ E++E E+E Q+EEK R + K E EK +D +K
Sbjct: 499 EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREE---KKTQEQEKKTWDQEEK 555
Query: 54 KRQNKDLMELQALIDSHFEARKKEEEELVALKERI---EKRRAERAEQQRIRAEK----- 105
R+ + + E + + E +++EE++ +E++ E++ E+ E+ + + EK
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 106 ----ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQ 161
E+E ++++ E++ E++ K + +++ K + M + ++ +G+++
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE-KMWEQEEKMREQEEKMREQEEKMQGQEE 674
Query: 162 TAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQL--EIDKFEFGEKLKRQKYD 219
RE ++K+ + K E+K+R + +++W ++ + +K E+++ ++
Sbjct: 675 KMREQEEKMQGQEEKMRE----QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEER 730
Query: 220 ITTLRSRI-DQAQKHSKKAGTP 240
I + ++ ++ +H ++ P
Sbjct: 731 IRDQKEKMQERLPEHEERCSEP 752
Score = 52.8 bits (125), Expect = 3e-07
Identities = 47/228 (20%), Positives = 111/228 (48%), Gaps = 33/228 (14%)
Query: 8 QVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALI 67
QV+ +EE ++EEE++E+EK K+ + + RQ + L E + +
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEK--------------KIRKQEEKMWRQEERLREQEGKM 271
Query: 68 DSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKR 127
E +++E+ L ++ + ++ E EQ+++R E+E Q + EEK +EE +
Sbjct: 272 REQEEKMRRQEKRLREQEKELREQEKELREQKKLR---EQEEQMQEQEEKMWEQEEKMRE 328
Query: 128 RAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDK 187
+ E ++++ L + Q R ++Q R+ ++++ + + E++
Sbjct: 329 QEEKMWRQEERL----------WEQEKQMREQEQKMRDQEERMWEQDERLRE----KEER 374
Query: 188 LRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSK 235
+R++ K +WE +++ ++ E+ K+ + + T+R + ++ QK +
Sbjct: 375 MREQEK-MWEQEEKMQ-EEERIREREKKMREEEETMREQEEKMQKQEE 420
Score = 51.2 bits (121), Expect = 8e-07
Identities = 50/217 (23%), Positives = 97/217 (44%), Gaps = 29/217 (13%)
Query: 10 EEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDS 69
EE ++ E QE+ + E EK +L ++++K + + Q ++
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVK-----------ELKRKLERAKFLLPQVQTNT 231
Query: 70 HFEARKKEEEELVALKERIEK------RRAERAEQQRIRAEKERERQNRLAEEKARREEE 123
E ++EEEL +++I K R+ ER +Q + ++ E+ R +EK RE+E
Sbjct: 232 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR--QEKRLREQE 289
Query: 124 DAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE---MKKKILAERRKPLNI 180
R E +L+++K L K ++ K + E +++ L E+ K +
Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 349
Query: 181 DHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 217
E K+RD+ + +WE +L E E+++ Q+
Sbjct: 350 Q---EQKMRDQEERMWEQDERLR----EKEERMREQE 379
Score = 49.7 bits (117), Expect = 2e-06
Identities = 42/174 (24%), Positives = 90/174 (51%), Gaps = 14/174 (8%)
Query: 1 MSDEEVEQVEEQ----YEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 56
M E+ E+++EQ E+EE+ E+EE +E++ + K+ E E+ D K ++
Sbjct: 575 MMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED-----KMQE 629
Query: 57 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
+++M Q E + E+EE ++E+ EK R E+ E+ + + EK RE++ ++ +
Sbjct: 630 QEEMMWEQEEKMQEQEEKMWEQEE--KMREQEEKMR-EQEEKMQGQEEKMREQEEKMQGQ 686
Query: 117 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 170
+ + E++ K R +++ + G + ++ R K++ R+ K+K+
Sbjct: 687 EEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMW--GQEEMREKEERIRDQKEKM 738
Score = 37.7 bits (86), Expect = 0.009
Identities = 40/199 (20%), Positives = 88/199 (44%), Gaps = 23/199 (11%)
Query: 54 KRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 113
K++N +L E L +S E+ + L + KR+ ERA+ + + ++
Sbjct: 186 KKKNAELQEKLRLAES--------EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMW 237
Query: 114 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 173
+E+ RE+E R+ E+ + +++ L + + K +++ ++K L E
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQE----------ERLREQEGKMREQEEKMRRQEKRLRE 287
Query: 174 RRKPLNIDHLGEDKLRD--KAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 231
+ K L E +LR+ K +E E + + E +E EK++ Q+ + R+ + +
Sbjct: 288 QEKELREQ---EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
Query: 232 KHSKKAGTPAKGKVGGRWK 250
K ++ + + W+
Sbjct: 345 KQMREQEQKMRDQEERMWE 363
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 63.9 bits (154), Expect = 1e-10
Identities = 54/246 (21%), Positives = 134/246 (54%), Gaps = 26/246 (10%)
Query: 3 DEEVEQVEEQYEEEEEA--QEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
+E++ + EE+ E+EE ++EE+++E+E+ + K+ E EK+ + +K+++ +D
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE--EEKMHEQEKI--WEEEKRQEQEDK 571
Query: 61 MELQALIDSHFEARKKEEEELVALKERI---EKRRAERAEQQRIRAEKERERQNRLAEEK 117
M Q E +++EE++ +E+I E++R E+ E+ + EK RE++ ++ E++
Sbjct: 572 MWRQE------EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625
Query: 118 ARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKP 177
+ E++ K R ++++ +++ MG + ++ + +++T ++KI + +K
Sbjct: 626 EKIREQEEKIREQEEMTQEQE-EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKI 684
Query: 178 LNIDHL---GEDKLRDKAKELWETLHQL---EIDKFEFGEKLKRQKYDI----TTLRSRI 227
+ E+ ++++ +++WE ++ E E EK++RQ+ + LR +
Sbjct: 685 REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 744
Query: 228 DQAQKH 233
++ Q+H
Sbjct: 745 EKMQEH 750
Score = 61.2 bits (147), Expect = 8e-10
Identities = 55/236 (23%), Positives = 119/236 (50%), Gaps = 35/236 (14%)
Query: 7 EQVEEQYEEEEEAQE-EEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQA 65
+Q E+ + +EE+ QE EE++QE+E+ KI E E+ + +K R+ +++M +
Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEE--------KIREQEEKIREQEEKMRRQEEMMWEK- 347
Query: 66 LIDSHFEARKKEEEELVALKERIEKRRAE-----------RAEQQRIRAEKERERQNRLA 114
E + + +EE++ KE +R+ E + E + EK RE + ++
Sbjct: 348 ------EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 401
Query: 115 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 174
E++ RE+E+ KR+ E+ +++++ A + ++ R +++ RE +KK+ +
Sbjct: 402 EQEKIREQEE-KRQEEEKIREQEKRQEQEA---KMWRQEEKIREQEEKIREQEKKMWRQE 457
Query: 175 RKPLNIDHLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDITTLRSRI 227
K + + E++ R + +E+W E +H+ E + + EK+ Q+ I ++
Sbjct: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE-EIWRQKEKMHEQEEKIRKQEEKV 512
Score = 61.2 bits (147), Expect = 8e-10
Identities = 52/243 (21%), Positives = 117/243 (48%), Gaps = 27/243 (11%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
EE +E+ E+EE ++EEE E++ R + A + EK+ + + + Q K +
Sbjct: 397 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 456
Query: 64 QALIDS----HFEARKKEEEELVALKERIEK-----RRAERAEQQRIRAEKERERQNRLA 114
+ I E +++E+EE+ +E+I + R+ E+ +Q + K+ E+ R
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR-Q 515
Query: 115 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 174
EEK R +EE + + E ++++ + + ++ +++ ++KI E
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKI------------REQEEMWREEEKMHEQEKIWEEE 563
Query: 175 RKPLNIDHL--GEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQ 229
++ D + E+K+R++ +++W E + + E + E EK+ +Q+ I +I +
Sbjct: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQE 623
Query: 230 AQK 232
++
Sbjct: 624 QEE 626
Score = 60.5 bits (145), Expect = 1e-09
Identities = 55/259 (21%), Positives = 127/259 (49%), Gaps = 28/259 (10%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+E++ + E+ E+EE+ QEEE+++E+EK R + A + EK+ + + + Q K +
Sbjct: 397 EEKMHEQEKIREQEEKRQEEEKIREQEK-RQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Query: 63 LQALIDSHF----EARKKEEEELVALKERIEK-----RRAERAEQQ--RIRAEKER---- 107
+ I E +++E+EE+ +E+I + R+ E+ +Q +IR ++E+
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
Query: 108 ERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA---- 163
E + R EEK R +EE R+ E ++++ + ++KR +++
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ 575
Query: 164 ----REMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYD 219
RE ++K+ + K E+K +++ +++W+ ++ + + E+ ++ +
Sbjct: 576 EEKIREQEEKVWRQEEKIRE----QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ 631
Query: 220 ITTLRSRIDQAQKHSKKAG 238
+R + + Q+ +K G
Sbjct: 632 EEKIREQEEMTQEQEEKMG 650
Score = 51.2 bits (121), Expect = 8e-07
Identities = 49/237 (20%), Positives = 115/237 (48%), Gaps = 35/237 (14%)
Query: 3 DEEVEQVEEQYEEEEEA---QEEEEVQEEEKPRPKLTA-----PKIPEGEKVDFDDIQKK 54
+E++ + EE+ E+EE QEE ++EEK R + K+ E++ ++ +K
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 379
Query: 55 RQNKDLM--------ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKE 106
R+ +++M EL+ + + R++EE+ K R +++R E+ + + EK
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 439
Query: 107 RERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREM 166
RE++ ++ E++ + ++ K ++ +++++ + + ++K +++
Sbjct: 440 REQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE-----QEEMWRQEEKIHEQEEIWRQ 494
Query: 167 KKKILAERRKPLNIDHLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDI 220
K+K+ H E+K+R + +++W E + + E E EK+ RQ+ I
Sbjct: 495 KEKM-----------HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Score = 51.2 bits (121), Expect = 8e-07
Identities = 47/224 (20%), Positives = 108/224 (48%), Gaps = 13/224 (5%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+E Q E+ +E+EE +++E++ E+E+ K + EK+ + + + Q + +
Sbjct: 476 EEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR 535
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL--AEEKARR 120
+ I E ++EE+ K E++R E+ ++ + EK RE++ ++ EEK R
Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE 595
Query: 121 EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQK----RGKKQTAREMKKKILAERRK 176
+EE + + E K+++ + K ++ R +++ +E ++K+ + K
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 177 PLNIDHLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQK 217
E+K++++ + +W E + + E E EK++ Q+
Sbjct: 656 MCE----QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE 695
Score = 43.5 bits (101), Expect = 2e-04
Identities = 58/250 (23%), Positives = 124/250 (49%), Gaps = 30/250 (12%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEE--EVQEEEKP------RPKLTAPKIPEGEKVDFDDIQ 52
++DEE+++ + +E+ + E E E+Q K R KL P+ + + + D +
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 271
Query: 53 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERE 108
K+ Q+ +LQA ++ + +++EE++ +E+I++ + EQ+ +IR ++E+
Sbjct: 272 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 109 RQNRLAEEKARREEE-----DAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA 163
R+ EEK RR+EE + K R ++++ +K M K ++ R +++
Sbjct: 331 REQ---EEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKMRRQEEMM 386
Query: 164 REMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGE-KLKRQKYDITT 222
E ++KI + L ++K+R++ ++ E E +K + E K+ RQ+ I
Sbjct: 387 WEKEEKI-----RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 441
Query: 223 LRSRIDQAQK 232
+I + +K
Sbjct: 442 QEEKIREQEK 451
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 63.2 bits (152), Expect = 2e-10
Identities = 52/252 (20%), Positives = 125/252 (49%), Gaps = 26/252 (10%)
Query: 7 EQVEEQYEEEEEAQEEEE--------VQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 58
+Q E+ + +EE+ QE+EE ++E+E+ + + EK+ + + RQ +
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
Query: 59 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAER-AEQQRIRAEKERERQNRLAEEK 117
+ E + I E ++EE++ E+I+++ E ++++IR ++E+ ++ +EK
Sbjct: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413
Query: 118 ARREEEDAKRRAEDDL----KKKKALSSMGANYSSYLAKADQK--------RGKKQTARE 165
RE+++ R E+++ +K + L M + L + ++K + +++ +
Sbjct: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 166 MKKKILAERRKPLNIDHL--GEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDI 220
++KI + K + L E+K+ ++ +++W E + + E E EK++RQ+ +
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM 533
Query: 221 TTLRSRIDQAQK 232
R+ Q ++
Sbjct: 534 REQEVRLWQQEE 545
Score = 52.0 bits (123), Expect = 5e-07
Identities = 47/215 (21%), Positives = 105/215 (48%), Gaps = 37/215 (17%)
Query: 3 DEEV-EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLM 61
DE++ EQ EE + +EE+ +E+EE ++E+ R + + + EK+ + + RQ + +
Sbjct: 380 DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE--QDEKIREQEEEMWRQEEKIR 437
Query: 62 ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARRE 121
EL+ E + +EE+L ++E++++ + EQ EEK +R+
Sbjct: 438 ELE-------EMMQDQEEKLREVEEKMQEEEEKMQEQ----------------EEKIQRQ 474
Query: 122 EEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNID 181
EE + + E +++K L + + ++K +++ +++ + E+ + +
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQ-----EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
Query: 182 HLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKL 213
E+K+R++ LW E + + E+ E E+L
Sbjct: 530 ---EEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 43.5 bits (101), Expect = 2e-04
Identities = 26/116 (22%), Positives = 68/116 (58%), Gaps = 4/116 (3%)
Query: 3 DEEVEQVEEQYEEEEE--AQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
+E++++ EE+ +E+EE ++EE++QE+E+ + + + EK+ + + RQ + +
Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQEEKIQEQEE-KTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512
Query: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
E + + E +++EE++ + R+ ++ E+ ++Q +R ++ ER +L ++
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE-EKMQEQEVRLQELEERLGKLGQK 567
Score = 29.6 bits (65), Expect = 2.6
Identities = 42/231 (18%), Positives = 93/231 (40%), Gaps = 33/231 (14%)
Query: 15 EEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEAR 74
+E++ EE E ++ K K +P+ E ++ + ++N D ++ S + +
Sbjct: 85 DEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVK-----SSFKKRQ 139
Query: 75 KKEEEELVALKERI----------EKRRAERAEQQRIRAEKERERQNRLAE--EKARREE 122
+K E+ ++R+ E +R E + + R+ EK +E
Sbjct: 140 EKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKER 199
Query: 123 EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQ-TAREMKKK------ILAERR 175
+ + + L A L + ++ + Q +++K+K +L +++
Sbjct: 200 DAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQ 259
Query: 176 KPLNIDHLGEDKLRDKAK--------ELWETLHQLEIDK-FEFGEKLKRQK 217
+ D LG++ AK ELW L+Q + +K + EK++ Q+
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 63.2 bits (152), Expect = 2e-10
Identities = 52/252 (20%), Positives = 125/252 (49%), Gaps = 26/252 (10%)
Query: 7 EQVEEQYEEEEEAQEEEE--------VQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 58
+Q E+ + +EE+ QE+EE ++E+E+ + + EK+ + + RQ +
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
Query: 59 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAER-AEQQRIRAEKERERQNRLAEEK 117
+ E + I E ++EE++ E+I+++ E ++++IR ++E+ ++ +EK
Sbjct: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413
Query: 118 ARREEEDAKRRAEDDL----KKKKALSSMGANYSSYLAKADQK--------RGKKQTARE 165
RE+++ R E+++ +K + L M + L + ++K + +++ +
Sbjct: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 166 MKKKILAERRKPLNIDHL--GEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDI 220
++KI + K + L E+K+ ++ +++W E + + E E EK++RQ+ +
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM 533
Query: 221 TTLRSRIDQAQK 232
R+ Q ++
Sbjct: 534 REQEVRLWQQEE 545
Score = 52.0 bits (123), Expect = 5e-07
Identities = 47/215 (21%), Positives = 105/215 (48%), Gaps = 37/215 (17%)
Query: 3 DEEV-EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLM 61
DE++ EQ EE + +EE+ +E+EE ++E+ R + + + EK+ + + RQ + +
Sbjct: 380 DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE--QDEKIREQEEEMWRQEEKIR 437
Query: 62 ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARRE 121
EL+ E + +EE+L ++E++++ + EQ EEK +R+
Sbjct: 438 ELE-------EMMQDQEEKLREVEEKMQEEEEKMQEQ----------------EEKIQRQ 474
Query: 122 EEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNID 181
EE + + E +++K L + + ++K +++ +++ + E+ + +
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQ-----EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
Query: 182 HLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKL 213
E+K+R++ LW E + + E+ E E+L
Sbjct: 530 ---EEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 43.5 bits (101), Expect = 2e-04
Identities = 26/116 (22%), Positives = 68/116 (58%), Gaps = 4/116 (3%)
Query: 3 DEEVEQVEEQYEEEEE--AQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
+E++++ EE+ +E+EE ++EE++QE+E+ + + + EK+ + + RQ + +
Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQEEKIQEQEE-KTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512
Query: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
E + + E +++EE++ + R+ ++ E+ ++Q +R ++ ER +L ++
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE-EKMQEQEVRLQELEERLGKLGQK 567
Score = 29.6 bits (65), Expect = 2.6
Identities = 42/231 (18%), Positives = 93/231 (40%), Gaps = 33/231 (14%)
Query: 15 EEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEAR 74
+E++ EE E ++ K K +P+ E ++ + ++N D ++ S + +
Sbjct: 85 DEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVK-----SSFKKRQ 139
Query: 75 KKEEEELVALKERI----------EKRRAERAEQQRIRAEKERERQNRLAE--EKARREE 122
+K E+ ++R+ E +R E + + R+ EK +E
Sbjct: 140 EKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKER 199
Query: 123 EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQ-TAREMKKK------ILAERR 175
+ + + L A L + ++ + Q +++K+K +L +++
Sbjct: 200 DALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQ 259
Query: 176 KPLNIDHLGEDKLRDKAK--------ELWETLHQLEIDK-FEFGEKLKRQK 217
+ D LG++ AK ELW L+Q + +K + EK++ Q+
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 63.2 bits (152), Expect = 2e-10
Identities = 49/230 (21%), Positives = 115/230 (50%), Gaps = 11/230 (4%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+E++ ++EE+ E+E+ +E+EE ++EE+ KI E EK + + RQ + + E
Sbjct: 437 EEKIRELEEKMHEQEKIREQEEKRQEEE--------KIREQEKRQEQEAKMWRQEEKIRE 488
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREE 122
+ I E ++EE++ ++ E+ + + E+ + EK RE++ +++ E+
Sbjct: 489 QEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ 548
Query: 123 EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDH 182
E+ R+ E+ + +++ M + ++ +++ RE ++KI + K +
Sbjct: 549 EEKIRKQEEKMWRQE--EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606
Query: 183 LGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 232
+ +++ +K E E + + E E EK++RQ+ I +I + ++
Sbjct: 607 MTQEQ-EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Score = 62.4 bits (150), Expect = 4e-10
Identities = 53/227 (23%), Positives = 118/227 (51%), Gaps = 28/227 (12%)
Query: 7 EQVEEQYEEEEEAQE-EEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQA 65
+Q E+ + +EE+ QE EE++QE+E+ KI E E+ + +K R+ +++M +
Sbjct: 358 QQEEKMWRQEEKIQEWEEKIQEQEE--------KIREQEEKIREQEEKMRRQEEMMWEK- 408
Query: 66 LIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDA 125
E + + +EE++ KE +R+ E + + EK RE + ++ E++ RE+E+
Sbjct: 409 ------EEKMRRQEEMMWEKEEKMRRQEEMMWE---KEEKIRELEEKMHEQEKIREQEE- 458
Query: 126 KRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGE 185
KR+ E+ +++++ A + ++ R +++ RE ++K+ + K + + E
Sbjct: 459 KRQEEEKIREQEKRQEQEA---KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515
Query: 186 DKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 232
++ R + +E+W + +K E++ RQK I +I + ++
Sbjct: 516 EEKRQEQEEMWR-----QEEKIREQEEIWRQKEKIHEQEEKIRKQEE 557
Score = 60.8 bits (146), Expect = 1e-09
Identities = 57/257 (22%), Positives = 127/257 (49%), Gaps = 28/257 (10%)
Query: 3 DEEVEQVEEQYEEEEEA---QEEEEVQEEEKPRPKLTA-----PKIPEGEKVDFDDIQKK 54
+E++++ EE+ +E+EE QEE+ ++EEK R + K+ E++ ++ +K
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
Query: 55 RQNKDLM--------ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKE 106
R+ +++M EL+ + + R++EE+ K R +++R E+ + + EK
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486
Query: 107 RERQNRL--AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAR 164
RE++ ++ EEK R+EE + + ++K+ + + ++ +K+
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIH 546
Query: 165 EMKKKILAERRKPLNID---HLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIT 221
E ++KI + K + H E+K+R++ +++W ++ E EK++ Q+ I
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR----EQEEKIREQEEKI- 601
Query: 222 TLRSRIDQAQKHSKKAG 238
R + + Q+ +K G
Sbjct: 602 --REQEEMTQEQEEKMG 616
Score = 56.6 bits (135), Expect = 2e-08
Identities = 57/275 (20%), Positives = 132/275 (48%), Gaps = 43/275 (15%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPE-GEKVDFDDIQKKRQNKD 59
M ++E + +E+ +EEE E+E ++E++ + KI E EK+ + + RQ +
Sbjct: 447 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEK 506
Query: 60 LMELQALIDSHFEARKKEEEELVALKERIEK-----RRAERAEQQRIRAEKERERQNRL- 113
+ E + + + E +++E+EE+ +E+I + R+ E+ +Q + K+ E+ R
Sbjct: 507 IHEQEKIRE---EEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQE 563
Query: 114 -----AEEKAR-------------REEEDAKRRAEDDLKKKKALS-----SMGANYSSYL 150
EEK R RE+E+ R E+ +++++ ++ MG
Sbjct: 564 EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 623
Query: 151 AKADQKRGKKQTAREMKKKILAERRKPLNIDHL---GEDKLRDKAKELWETLHQL---EI 204
+ ++ + +++ R ++KI + +K + E+ ++++ +++WE ++ E
Sbjct: 624 EQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 683
Query: 205 DKFEFGEKLKRQKYDI----TTLRSRIDQAQKHSK 235
E EK++RQ+ + LR + ++ Q+H +
Sbjct: 684 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 44.7 bits (104), Expect = 8e-05
Identities = 56/259 (21%), Positives = 130/259 (50%), Gaps = 50/259 (19%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEE--EVQEEEKP------RPKLTAPKIPEGEKVDFDDIQ 52
++DEE+++ + +E+ + E E E+Q K R KL P+ + + + D +
Sbjct: 275 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 332
Query: 53 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERE 108
K+ Q+ +LQA ++ + +++EE++ +E+I++ + EQ+ +IR ++E+
Sbjct: 333 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 391
Query: 109 RQNRLAEEKARREEE-----DAKRRAEDDL----------------KKKKALSSM--GAN 145
R+ EEK RR+EE + K R ++++ +K++ + + +
Sbjct: 392 REQ---EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 146 YSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHL--GEDKLRDKAKELW---ETLH 200
+ + ++KR +++ RE +K+ E + + + E+K+R++ +++W E +H
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 201 QLEIDKFEFGEKLKRQKYD 219
+ E + E+ KRQ+ +
Sbjct: 509 EQE----KIREEEKRQEQE 523
Score = 33.9 bits (76), Expect = 0.14
Identities = 19/83 (22%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
Query: 3 DEEVEQVEEQYEEEEEA--QEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
+E++ + E++ E+EE ++EE +QE+E+ + + EK+ + + +RQ + +
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699
Query: 61 MELQALIDSHFEARKKEEEELVA 83
E + + E ++ +E L A
Sbjct: 700 WEQEVRLRQQEEKMQEHQEHLEA 722
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 62.4 bits (150), Expect = 4e-10
Identities = 56/236 (23%), Positives = 122/236 (51%), Gaps = 32/236 (13%)
Query: 7 EQVEEQYEEEEEAQE-EEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQA 65
+Q E+ + +EE+ QE EE++QE+E+ KI E E+ + +K R+ +++M +
Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEE--------KIREQEEKIREQEEKMRRQEEMMWEK- 347
Query: 66 LIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDA 125
E + + +EE++ KE + RR E E + EK RE + ++ E++ RE+E+
Sbjct: 348 ------EEKMRRQEEMMWEKEE-KMRRLE--EMMWEKEEKIRELEEKMHEQEKIREQEE- 397
Query: 126 KRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGE 185
KR+ E+ +++++ A + ++ R +++ RE +KK+ + K + + E
Sbjct: 398 KRQEEEKIREQEKRQEQEAKM---WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 454
Query: 186 DKLRDKAKELWETLHQL--------EIDKFEFGEKLKRQKYDITTLRSRI-DQAQK 232
++ R + +E+W ++ + +K EK+++Q+ + ++ DQ +K
Sbjct: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK 510
Score = 61.2 bits (147), Expect = 8e-10
Identities = 46/202 (22%), Positives = 103/202 (50%), Gaps = 21/202 (10%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
++ EQ + + +EE+ +E+EE E++ + KI E EK+ ++ KRQ ++ M
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE---KRQEQEEMW 465
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER----ERQNRLAEEKA 118
Q E + +E+EE+ KE++ ++ R +++++ ++E+ E + R EEK
Sbjct: 466 RQ-------EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518
Query: 119 RREEEDAKRRAE---DDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERR 175
R+EE + + E + +K + M + + ++K +++ R ++KI +
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578
Query: 176 KPLNIDHLGEDKLRDKAKELWE 197
K ++K+R++ +++WE
Sbjct: 579 KIRE----QKEKIREQEEKIWE 596
Score = 60.1 bits (144), Expect = 2e-09
Identities = 54/248 (21%), Positives = 132/248 (53%), Gaps = 34/248 (13%)
Query: 3 DEEVEQVEEQYEEEEEA--QEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
+E++++ EE+ +E+EE ++EE+++E+E+ K+ E++ ++ +K R+ +++
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEE--------KMRRQEEMMWEKEEKMRRQEEM 357
Query: 61 M-----ELQALIDSHFEARKK--EEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 113
M +++ L + +E +K E EE + +E+I ++ +R E+++IR ++ +RQ +
Sbjct: 358 MWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR--EQEKRQEQE 415
Query: 114 A-----EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKK 168
A EEK R +EE + + + ++++ + + + ++KR +++ ++
Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKI------HEQEKIREEEKRQEQEEMWRQEE 469
Query: 169 KILAERRKPLNIDHLGE-DKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDITTLR 224
KI + + + E +K+R + +++W E +H E E EK+ RQ+ I
Sbjct: 470 KIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQE 529
Query: 225 SRIDQAQK 232
+I + ++
Sbjct: 530 EKIREQEE 537
Score = 59.3 bits (142), Expect = 3e-09
Identities = 53/237 (22%), Positives = 120/237 (50%), Gaps = 34/237 (14%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+E++ ++EE+ E+E+ +E+EE ++EE+ KI E EK + + RQ
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEE--------KIREQEKRQEQEAKMWRQ------ 421
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERA-EQQRIRAEKERERQNRL-AEEKARR 120
E + +E+EE + +E+ R+ E+ EQ++IR E++R+ Q + +E+ R
Sbjct: 422 ---------EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 472
Query: 121 EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNI 180
E+E+ R+ E +++K + + ++ +++ RE ++K+ + K
Sbjct: 473 EQEEIWRQKEKMHEQEK----IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ 528
Query: 181 DHL---GEDKLRDKAKELWETLHQL--EIDKFEFGEKLKRQKYDITTLRSRIDQAQK 232
+ E+K+R++ + + E ++ + +K + EK++RQ+ I +I + ++
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKE 585
Score = 56.6 bits (135), Expect = 2e-08
Identities = 60/239 (25%), Positives = 121/239 (50%), Gaps = 49/239 (20%)
Query: 3 DEEVEQVEEQYEEEEE--AQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
+E++ ++EE E+EE + EE++ E+EK R + K E EK+ Q+KRQ ++
Sbjct: 362 EEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ--EEKRQEEEKI---REQEKRQEQEA 416
Query: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERA-EQQRIRAEKERERQNRLAEEKAR 119
+ E + +E+EE + +E+ R+ E+ EQ++IR E++R+ Q EE R
Sbjct: 417 KMWRQ------EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ----EEMWR 466
Query: 120 REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLN 179
+EE K R ++++ ++K +K +++ R+ ++K+ + K
Sbjct: 467 QEE---KIREQEEIWRQK-----------------EKMHEQEKIRKQEEKVWRQEEKM-- 504
Query: 180 IDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAG 238
H E+K+R++ +++W ++ E EK++ Q+ I R + + Q+ +K G
Sbjct: 505 --HDQEEKIREQEEKMWRQEEKIR----EQEEKIREQEEKI---REQEEMMQEQEEKMG 554
Score = 56.6 bits (135), Expect = 2e-08
Identities = 39/198 (19%), Positives = 106/198 (53%), Gaps = 23/198 (11%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+E++ + EE + ++E+ E+E+++++E+ + + EK+ + + RQ + + E
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKE--RERQNRLAEEKAR- 119
+ I E +++EE + +E++ ++ + EQ+++R ++E RE++ ++ E+K +
Sbjct: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
Query: 120 REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLN 179
RE+E+ E+ +++++ + Q++ +K +E K + E+ + +
Sbjct: 588 REQEEKIWEQEEKIREQEEMM--------------QEQEEKMWEQEEK---MCEQEEKMQ 630
Query: 180 IDHLGEDKLRDKAKELWE 197
E+K+R + +++WE
Sbjct: 631 EQ---EEKMRRQEEKMWE 645
Score = 48.1 bits (113), Expect = 7e-06
Identities = 59/259 (22%), Positives = 129/259 (49%), Gaps = 50/259 (19%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEE--EVQEEEKP------RPKLTAPKIPEGEKVDFDDIQ 52
++DEE+++ + +E+ + E E E+Q K R KL P+ + + + D +
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 271
Query: 53 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERE 108
K+ Q+ +LQA ++ + +++EE++ +E+I++ + EQ+ +IR ++E+
Sbjct: 272 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 109 RQNRLAEEKARREEE-----DAKRRAEDDL-----KKKKALSSM-------------GAN 145
R+ EEK RR+EE + K R ++++ +K + L M +
Sbjct: 331 REQ---EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
Query: 146 YSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHL--GEDKLRDKAKELW---ETLH 200
+ + ++KR +++ RE +K+ E + + + E+K+R++ K++W E +H
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 201 QLEIDKFEFGEKLKRQKYD 219
+ E + E+ KRQ+ +
Sbjct: 448 EQE----KIREEEKRQEQE 462
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/120 (24%), Positives = 70/120 (58%), Gaps = 10/120 (8%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+E++ + EE+ +E+E+ + +EE E++ + + KI E E+ ++ +K R+ +++M+
Sbjct: 550 EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ 609
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREE 122
Q E ++EE++ +E+++ E+ E+ R + EK E++ RL +++ + +E
Sbjct: 610 EQE------EKMWEQEEKMCEQEEKMQ----EQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
Score = 46.2 bits (108), Expect = 3e-05
Identities = 41/166 (24%), Positives = 81/166 (48%), Gaps = 7/166 (4%)
Query: 3 DEEVEQVEEQYEEEEEA---QEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKD 59
+E++ EE+ E+EE QEE+ ++EEK R + KI E E++ + +K + ++
Sbjct: 501 EEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ--EEKIREQEEMMQEQEEKMGEQEE 558
Query: 60 LMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKAR 119
M+ Q + E +++EE++ KE+I ++ + EQ+ E+E Q + EEK
Sbjct: 559 KMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQ--EEKMW 616
Query: 120 REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 165
+EE + E ++++ + + Q+ K Q +E
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 35.4 bits (80), Expect = 0.047
Identities = 21/78 (26%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Query: 7 EQVEEQYEEEEEAQEEEEV-QEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQA 65
EQ E+ +E+EE+ +E+EE+ QE+E+ + + EK+ + + +RQ + + E +
Sbjct: 589 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 648
Query: 66 LIDSHFEARKKEEEELVA 83
+ E ++ +E L A
Sbjct: 649 RLRQQEEKMQEHQEHLEA 666
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 61.6 bits (148), Expect = 6e-10
Identities = 56/199 (28%), Positives = 103/199 (51%), Gaps = 34/199 (17%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEE--EEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 58
M +E+ +Q+E+++ + +E E+ EE EEK + K A K+ E E +++Q +
Sbjct: 591 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA-------RRKQEE 643
Query: 59 DLMELQALIDSHFEAR------KKEEEELVALKERIE-KRRAERAEQQRI---------- 101
+ L+ L E R KK+EEE L++ E KR AE+ EQ+R
Sbjct: 644 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 703
Query: 102 ---RAEKERERQNR-LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKR 157
R E+ER Q R LAE++ RRE+E + +AE +L++++ ++ + ++K+
Sbjct: 704 EQERREQERREQERQLAEQERRREQE--RLQAERELQERE--KALRLQKEQLQRELEEKK 759
Query: 158 GKKQTAREMKKKILAERRK 176
K++ R ++++ E+ K
Sbjct: 760 KKEEQQRLAERQLQEEQEK 778
Score = 58.5 bits (140), Expect = 5e-09
Identities = 66/261 (25%), Positives = 124/261 (47%), Gaps = 43/261 (16%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQ--EEEKPRPKLTAPKIPEGEKVD-----------FDD 50
EE EQ+ Q EE++ + EEV+ EE+ R L A + E K + D+
Sbjct: 549 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 608
Query: 51 IQKKRQNKDLMELQALIDS------HFEARKKEEEE---LVALKERIEKRRAERAEQQRI 101
+K + + L E +A + EAR+K+EEE L L++ E+RR + Q+
Sbjct: 609 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK-- 666
Query: 102 RAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQ 161
+ E+E+ER + AE K E+ + +RR ++ +++ + +Q+R ++Q
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQERREQE---------------RREQER-REQ 710
Query: 162 TAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIT 221
RE ++++ + R+ E +L+++ K L QL+ E EK K+++
Sbjct: 711 ERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ---RELEEKKKKEEQQRL 767
Query: 222 TLRSRIDQAQKHSKKAGTPAK 242
R ++ +K +K+A +K
Sbjct: 768 AERQLQEEQEKKAKEAAGASK 788
Score = 58.5 bits (140), Expect = 5e-09
Identities = 53/211 (25%), Positives = 107/211 (50%), Gaps = 22/211 (10%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+E + +V + E E+ +EE++ Q E+K + + E++ + +KK K + E
Sbjct: 575 EERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 634
Query: 63 LQALIDSHFEARK-----KEEEE------LVALKERIEKRRAERAEQQRIRAEKERERQN 111
++A EAR+ +EEEE L KE ++R + AE +R+ ++E+ER+
Sbjct: 635 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 694
Query: 112 RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA----REMK 167
+ E+ RRE+E RR ++ ++++ L+ +A+++ +++ A +E
Sbjct: 695 QERREQERREQE---RREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQL 751
Query: 168 KKILAERRKPLNIDHLGEDKLRD----KAKE 194
++ L E++K L E +L++ KAKE
Sbjct: 752 QRELEEKKKKEEQQRLAERQLQEEQEKKAKE 782
Score = 57.0 bits (136), Expect = 2e-08
Identities = 45/179 (25%), Positives = 87/179 (48%), Gaps = 14/179 (7%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
+++E+VE + ++EEEA+ +Q+EE+ R + + ++ + + ++K + K L E
Sbjct: 630 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL--LQKKKEEEQERLRKAAEAKRLAEQ 687
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER-QNRLAEEKARREE 122
+ E ++E+E + E+R ER EQ+R AE+ER R Q RL E+ +E
Sbjct: 688 R-------EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQER 740
Query: 123 EDA----KRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKP 177
E A K + + +L++KK L + +K+ K+ + + + P
Sbjct: 741 EKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSP 799
Score = 51.2 bits (121), Expect = 8e-07
Identities = 46/229 (20%), Positives = 112/229 (48%), Gaps = 12/229 (5%)
Query: 16 EEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL--IDSHFEA 73
E+E Q E ++ +E+ +L K+ E ++ ++++ KR+ + LQA ++ E
Sbjct: 536 EKERQRLENLRRKEEAE-QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 594
Query: 74 RKKE-EEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRR---- 128
+KK+ E++ + E+ EK + ER +++ + + ++ + E + ++EEE + R
Sbjct: 595 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV-EARRKQEEEARRLRWLQQ 653
Query: 129 AEDDLKKKKALSSMGANYSSYLAK-ADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDK 187
E++ + ++ L L K A+ KR +Q RE +++ R + E +
Sbjct: 654 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQ--REQERREQERREQERREQERREQE 711
Query: 188 LRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
R++ ++L E + E ++ + +L+ ++ + + ++ + + KK
Sbjct: 712 RREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKK 760
Score = 47.8 bits (112), Expect = 9e-06
Identities = 36/142 (25%), Positives = 76/142 (53%), Gaps = 9/142 (6%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+EE E +++EE QE E K + + E E+ + + +++R+ ++ E
Sbjct: 655 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 714
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAE----KERERQNRLAEEKA 118
+ + + R++E+E L A +E E+ +A R ++++++ E K++E Q RLAE +
Sbjct: 715 QERQLAE--QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQL 772
Query: 119 RREEEDAKRRAEDDLKKKKALS 140
+ E+E ++A++ KAL+
Sbjct: 773 QEEQE---KKAKEAAGASKALN 791
Score = 42.7 bits (99), Expect = 3e-04
Identities = 61/223 (27%), Positives = 101/223 (45%), Gaps = 29/223 (13%)
Query: 18 EAQEEEEVQEEEKPRPKLTAPKIP-EGEKVD---FDDIQKKRQNKDLME--------LQA 65
E EE+ +++EE P+ P P KV + ++N+ LM +++
Sbjct: 459 ELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKS 518
Query: 66 LIDSHFEARKKEEEELVAL-KERIEK-RRAERAEQQRIRAEKERERQNRLAEEKARREEE 123
I + R + V ++R+E RR E AEQ R R + E +++ RL E K +REE
Sbjct: 519 FIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLR-RQKVEEDKRRRLEEVKLKREER 577
Query: 124 -----DAKRRAED-DLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKP 177
A+ R E +KKK + A KA ++R ++ A KKK A++ +
Sbjct: 578 LRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKA---KKKAAAKKMEE 634
Query: 178 LNIDHLGED---KLRDKAKELWETLHQ--LEIDKFEFGEKLKR 215
+ E+ +LR +E E HQ L+ K E E+L++
Sbjct: 635 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK 677
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 61.6 bits (148), Expect = 6e-10
Identities = 56/199 (28%), Positives = 103/199 (51%), Gaps = 34/199 (17%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEE--EEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 58
M +E+ +Q+E+++ + +E E+ EE EEK + K A K+ E E +++Q +
Sbjct: 587 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA-------RRKQEE 639
Query: 59 DLMELQALIDSHFEAR------KKEEEELVALKERIE-KRRAERAEQQRI--------RA 103
+ L+ L E R KK+EEE L++ E KR AE+ EQ+R R
Sbjct: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
Query: 104 EKERERQNR------LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKR 157
E+ER Q R LAE++ RRE+E + +AE +L++++ ++ + ++K+
Sbjct: 700 EQERREQERREQERQLAEQERRREQE--RLQAERELQERE--KALRLQKEQLQRELEEKK 755
Query: 158 GKKQTAREMKKKILAERRK 176
K++ R ++++ E+ K
Sbjct: 756 KKEEQQRLAERQLQEEQEK 774
Score = 58.5 bits (140), Expect = 5e-09
Identities = 66/261 (25%), Positives = 124/261 (47%), Gaps = 43/261 (16%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQ--EEEKPRPKLTAPKIPEGEKVD-----------FDD 50
EE EQ+ Q EE++ + EEV+ EE+ R L A + E K + D+
Sbjct: 545 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 604
Query: 51 IQKKRQNKDLMELQALIDS------HFEARKKEEEE---LVALKERIEKRRAERAEQQRI 101
+K + + L E +A + EAR+K+EEE L L++ E+RR + Q+
Sbjct: 605 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK-- 662
Query: 102 RAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQ 161
+ E+E+ER + AE K E+ + +RR ++ +++ + +Q+R ++Q
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQERREQE---------------RREQER-REQ 706
Query: 162 TAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIT 221
RE ++++ + R+ E +L+++ K L QL+ E EK K+++
Sbjct: 707 ERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ---RELEEKKKKEEQQRL 763
Query: 222 TLRSRIDQAQKHSKKAGTPAK 242
R ++ +K +K+A +K
Sbjct: 764 AERQLQEEQEKKAKEAAGASK 784
Score = 58.5 bits (140), Expect = 5e-09
Identities = 53/211 (25%), Positives = 107/211 (50%), Gaps = 22/211 (10%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+E + +V + E E+ +EE++ Q E+K + + E++ + +KK K + E
Sbjct: 571 EERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 630
Query: 63 LQALIDSHFEARK-----KEEEE------LVALKERIEKRRAERAEQQRIRAEKERERQN 111
++A EAR+ +EEEE L KE ++R + AE +R+ ++E+ER+
Sbjct: 631 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 690
Query: 112 RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA----REMK 167
+ E+ RRE+E RR ++ ++++ L+ +A+++ +++ A +E
Sbjct: 691 QERREQERREQE---RREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQL 747
Query: 168 KKILAERRKPLNIDHLGEDKLRD----KAKE 194
++ L E++K L E +L++ KAKE
Sbjct: 748 QRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
Score = 57.0 bits (136), Expect = 2e-08
Identities = 45/179 (25%), Positives = 87/179 (48%), Gaps = 14/179 (7%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
+++E+VE + ++EEEA+ +Q+EE+ R + + ++ + + ++K + K L E
Sbjct: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL--LQKKKEEEQERLRKAAEAKRLAEQ 683
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER-QNRLAEEKARREE 122
+ E ++E+E + E+R ER EQ+R AE+ER R Q RL E+ +E
Sbjct: 684 R-------EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQER 736
Query: 123 EDA----KRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKP 177
E A K + + +L++KK L + +K+ K+ + + + P
Sbjct: 737 EKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSP 795
Score = 51.6 bits (122), Expect = 6e-07
Identities = 46/230 (20%), Positives = 113/230 (49%), Gaps = 12/230 (5%)
Query: 15 EEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL--IDSHFE 72
+E+E Q E ++ +E+ +L K+ E ++ ++++ KR+ + LQA ++ E
Sbjct: 531 KEKERQRLENLRRKEEAE-QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKE 589
Query: 73 ARKKE-EEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRR--- 128
+KK+ E++ + E+ EK + ER +++ + + ++ + E + ++EEE + R
Sbjct: 590 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV-EARRKQEEEARRLRWLQ 648
Query: 129 -AEDDLKKKKALSSMGANYSSYLAK-ADQKRGKKQTAREMKKKILAERRKPLNIDHLGED 186
E++ + ++ L L K A+ KR +Q RE +++ R + E
Sbjct: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQ--REQERREQERREQERREQERREQ 706
Query: 187 KLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
+ R++ ++L E + E ++ + +L+ ++ + + ++ + + KK
Sbjct: 707 ERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKK 756
Score = 47.8 bits (112), Expect = 9e-06
Identities = 36/142 (25%), Positives = 76/142 (53%), Gaps = 9/142 (6%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+EE E +++EE QE E K + + E E+ + + +++R+ ++ E
Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 710
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAE----KERERQNRLAEEKA 118
+ + + R++E+E L A +E E+ +A R ++++++ E K++E Q RLAE +
Sbjct: 711 QERQLAE--QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQL 768
Query: 119 RREEEDAKRRAEDDLKKKKALS 140
+ E+E ++A++ KAL+
Sbjct: 769 QEEQE---KKAKEAAGASKALN 787
Score = 38.1 bits (87), Expect = 0.007
Identities = 42/183 (22%), Positives = 80/183 (43%), Gaps = 26/183 (14%)
Query: 18 EAQEEEEVQEEEKPRPKLTAPKIP-EGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKK 76
E EE+ +++EE P+ P P KV ++ R ++ ++ + A +
Sbjct: 459 ELDEEQHLEDEELQPPRSKTPSSPCPASKV----VRPLRTFLHTVQRNQMLMTPTSAPRS 514
Query: 77 EEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKK 136
+ + +R R + E++R R E R ++ AE+ R++ E+ KRR +++K K
Sbjct: 515 VMKSFI---KRNTPLRMDPKEKERQRLENLRRKEE--AEQLRRQKVEEDKRRRLEEVKLK 569
Query: 137 KALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA-------ERRKPLNIDHLGEDKLR 189
+ L K Q R + + +E KKK + E+ + + L E+K +
Sbjct: 570 R---------EERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 620
Query: 190 DKA 192
KA
Sbjct: 621 KKA 623
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 61.2 bits (147), Expect = 8e-10
Identities = 52/203 (25%), Positives = 106/203 (52%), Gaps = 17/203 (8%)
Query: 14 EEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEA 73
+EE ++EE ++E+E+ + + E++ + + + Q + L E + + H E
Sbjct: 197 QEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEER 256
Query: 74 RKKEEEELVALKERI---EKRRAERAE-----QQRIRAEKER--ERQNRLAEEKARR-EE 122
++EE L +ER+ E+R E+ E ++R+R ++ER E++ RL E++ R E+
Sbjct: 257 LCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ 316
Query: 123 EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDH 182
E+ R E+ L +++ L +Q+R +++ R ++++ L E + L
Sbjct: 317 EERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEEL---- 372
Query: 183 LGEDKLRDKAKELW--ETLHQLE 203
L +++LR + + LW ETL +LE
Sbjct: 373 LEQERLRQQDERLWQQETLQELE 395
Score = 48.1 bits (113), Expect = 7e-06
Identities = 35/116 (30%), Positives = 61/116 (52%), Gaps = 10/116 (8%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQAL 66
EQ E E+EE +E+EE E++ R + ++ E EK+ Q + L E++ L
Sbjct: 294 EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLP-------GQERLLEEVEKL 346
Query: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREE 122
++ + R++EE+E + +ER+ + E EQ+R+R + ER Q +E R E
Sbjct: 347 LE---QERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRE 399
Score = 45.1 bits (105), Expect = 6e-05
Identities = 47/217 (21%), Positives = 104/217 (47%), Gaps = 24/217 (11%)
Query: 5 EVEQVEEQYEEEEEAQEE--EEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+VEQ++++ + E ++Q E + L+ + E++ + + + Q + L E
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLRE 217
Query: 63 LQALIDSHFEARKKEEEELVALKERI----------EKRRAERAE-----QQRIRAEKER 107
+ + E +++EE L +ER+ E+R E+ E ++R+R ++ER
Sbjct: 218 QEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEER 277
Query: 108 --ERQNRLAEEKAR-REEEDAKRRAEDDLKKKK----ALSSMGANYSSYLAKADQKRGKK 160
E++ RL E++ R RE+E+ E+ L++++ L + ++ G++
Sbjct: 278 LHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQE 337
Query: 161 QTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWE 197
+ E++K + ERR+ L ++L ++ +EL E
Sbjct: 338 RLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLE 374
Score = 42.7 bits (99), Expect = 3e-04
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 16/198 (8%)
Query: 37 APKIPEG-EKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER 95
AP+ P G KV+ Q + + L + + +A + + L L R E+R E+
Sbjct: 149 APEPPAGPSKVE----QLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQ 204
Query: 96 AEQQRIRAEKERERQNRLAEEKAR-REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKAD 154
E+ R + E+ RE++ RL E++ R RE+E+ R E+ L +++ + L + +
Sbjct: 205 EERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQE---ERLREHEERLCEQE 261
Query: 155 QKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLK 214
++ +++ +++ L E+ + L E++LR++ + L E +L E E+L
Sbjct: 262 ERLCEQEERLREQEERLHEQEERLCEQ---EERLREQEERLCEQEERLR----EQEERLC 314
Query: 215 RQKYDITTLRSRIDQAQK 232
Q+ + R+ + +K
Sbjct: 315 EQEERLREQEERLCEQEK 332
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 61.2 bits (147), Expect = 8e-10
Identities = 53/239 (22%), Positives = 120/239 (50%), Gaps = 25/239 (10%)
Query: 3 DEEVEQVEEQYEEEEEA--QEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
+E++ + EE+ +E EE ++EE+++E+E+ K+ E++ ++ +K R+ +++
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEE--------KMRRQEEMMWEKEEKMRRQEEM 338
Query: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR---LAEEK 117
M + E + +E EE + +E+I ++ +R E+++IR +++R+ Q EEK
Sbjct: 339 MWEK-------EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 391
Query: 118 ARREEEDAKRR----AEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 173
R +EE + + E + K + M + ++ R +++ RE +KKI +
Sbjct: 392 IREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ 451
Query: 174 RRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 232
K + + +++ +K E + + E E EK++RQ+ I +I + ++
Sbjct: 452 EEKIREQEEMMQEQ-EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Score = 61.2 bits (147), Expect = 8e-10
Identities = 54/241 (22%), Positives = 124/241 (51%), Gaps = 31/241 (12%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 60
M ++E + +E+ +EEE E+E ++E++ + KI E E +K R+ +++
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE-------EKIREQEEM 405
Query: 61 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKAR- 119
M+ Q E ++EE++ +E ++ E+ E+ R + EK RE++ ++ E++ +
Sbjct: 406 MQEQE------EKMGEQEEKMWEQEEEMQ----EQEEKMRRQEEKIREQEKKIREQEEKI 455
Query: 120 REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLN 179
RE+E+ + E+ + +++ M + + ++ R +++ RE +KKI + K
Sbjct: 456 REQEEMMQEQEEKMGEQE--GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 513
Query: 180 IDHLGEDKLRDKAKELWETLHQL---EIDKFEFGEKLKRQKYDI----TTLRSRIDQAQK 232
E+ ++++ +++WE ++ E E EK++RQ+ + LR + ++ Q+
Sbjct: 514 ----QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Query: 233 H 233
H
Sbjct: 570 H 570
Score = 48.9 bits (115), Expect = 4e-06
Identities = 55/261 (21%), Positives = 127/261 (48%), Gaps = 38/261 (14%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEE--EVQEEEKP------RPKLTAPKIPEGEKVDFDDIQ 52
++DEE+++ + +E+ + E E E+Q K R KL P+ + + + D +
Sbjct: 202 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 259
Query: 53 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER 109
K+ Q+ +LQA ++ + +++EE++ +E+I++R + EQ+ +E+E
Sbjct: 260 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEE--KIREQEE 316
Query: 110 QNRLAEEKARREEEDAKRRAEDDLKKKKALSSM--GANYSSYLAKADQKRGKKQTAREMK 167
+ R EE +EE +R+ E +K++ + + + + + ++KR +++ RE +
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376
Query: 168 K-------------KILAERRKPLNIDHL---GEDKLRDKAKELWETLHQLEIDKFEFGE 211
K KI + K + + E+K+ ++ +++WE +++ E E
Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ----EQEE 432
Query: 212 KLKRQKYDITTLRSRIDQAQK 232
K++RQ+ I +I + ++
Sbjct: 433 KMRRQEEKIREQEKKIREQEE 453
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 60.5 bits (145), Expect = 1e-09
Identities = 66/273 (24%), Positives = 128/273 (46%), Gaps = 50/273 (18%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
E+ EQ +EQ E E +EE++++ E+ + + K+ ++ + + ++Q +L+
Sbjct: 277 EQREQEKEQMLEYMEQLQEEDLKDMERRQQQ----KLKMQAEIKRINDENQKQKAELLAQ 332
Query: 64 QALID--------------SHFEA-----RKKEEEELVALKERIEKRRAERAEQQRIRAE 104
+ L D + FEA R+++E+E+ L+ EK + +AEQ +RA+
Sbjct: 333 EKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAK 392
Query: 105 KERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAR 164
+ +E +R E R+E+E+A+++ E + + +K+ A LA + Q R
Sbjct: 393 RNQEVADR---EWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAV------QVQRDR 443
Query: 165 EMKKKILAERRKPLNIDHLGEDK-----------LRDKAKELWETLHQLEIDKFEFGEKL 213
+ ++IL +R+ + + L E+K LR + +E + Q I FE G +L
Sbjct: 444 DEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRL 503
Query: 214 KRQKYDITTLRSRIDQAQKHS----KKAGTPAK 242
K + R RID+ ++ + G P K
Sbjct: 504 KE---EAQKRRERIDEIKRKKLEELRATGLPEK 533
Score = 47.0 bits (110), Expect = 2e-05
Identities = 46/171 (26%), Positives = 80/171 (46%), Gaps = 24/171 (14%)
Query: 6 VEQVEEQYEEEEEA----QEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLM 61
+++ + Y+ E++A + +E E + + K A K E E +++K R +
Sbjct: 375 MQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEA----ELRKSRLEQVAF 430
Query: 62 ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQ------------QRIRAEKERER 109
+ AL R + E L A +E+IEK R E ++ +++R +++E
Sbjct: 431 KEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEV 490
Query: 110 QNRLA--EEKARREEEDAKRRAEDDLKKKKALSSMGAN--YSSYLAKADQK 156
QNR+A EE R +EE KRR D K+K L + A Y +A++K
Sbjct: 491 QNRIATFEEGRRLKEEAQKRRERIDEIKRKKLEELRATGLPEKYCIEAERK 541
Score = 41.6 bits (96), Expect = 7e-04
Identities = 52/239 (21%), Positives = 114/239 (47%), Gaps = 16/239 (6%)
Query: 6 VEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQA 65
++Q E + ++ + EEV +E A K+ ++ + D+ K N + A
Sbjct: 149 MKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIILNA---KCHA 205
Query: 66 LIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARRE--EE 123
+ D+ +++ ++EL ++R+++ E Q+ I+ ++E ER+ R + RR+ E+
Sbjct: 206 IRDAQILEKQQIQKELDTEEKRLDQMM-EVERQKSIQRQEELERKRREERIRGRRQIVEQ 264
Query: 124 DAKRRAEDDL--KKKKALSSMGANYSSYLAKADQKRGKKQTAREMK-----KKILAERRK 176
K + E L ++++ Y L + D K +++ +++K K+I E +K
Sbjct: 265 MEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQK 324
Query: 177 PLNIDHLGEDKLRDKAKELWETLHQLEIDKFEF-GEKLKRQK-YDITTLRSRIDQAQKH 233
+ L ++KL D+ + +FE E+++R+K +I LR+ ++AQ +
Sbjct: 325 Q-KAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDY 382
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 60.1 bits (144), Expect = 2e-09
Identities = 51/215 (23%), Positives = 111/215 (51%), Gaps = 21/215 (9%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL--- 63
E+ E +YE +EEEEV E+E + +P + D ++ +++NK+ E
Sbjct: 315 EKDETEYEYSGSEEEEEEVPEQEGEPSSIV--NVPGESTLRRDFLRLQQENKERSEALRR 372
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKA--RRE 121
Q L+ + R++EE + L ER ++ ++ +++R+ ++ RER+ R +E+ RRE
Sbjct: 373 QQLLQEQ-QLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRRE 431
Query: 122 EEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNID 181
+E+ +R E + ++K+ +A++++ + + +E ++ L E ++ L +
Sbjct: 432 QEEKRRLEELERRRKE---------EEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEV- 481
Query: 182 HLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQ 216
L + L+++A L E+++ E+L+RQ
Sbjct: 482 -LQQQLLQEQAMLL--ECRWREMEEHRQAERLQRQ 513
Score = 34.7 bits (78), Expect = 0.080
Identities = 44/143 (30%), Positives = 62/143 (43%), Gaps = 54/143 (37%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEV-----QEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 58
E+ ++EEQ E EA+ ++E ++EEK R
Sbjct: 404 EQRRRLEEQQRREREARRQQEREQRRREQEEKRR-------------------------- 437
Query: 59 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER------QNR 112
L EL E R+KEEEE +E EKRR ER EQ+ IR + E E+ Q +
Sbjct: 438 -LEEL--------ERRRKEEEERRRAEE--EKRRVER-EQEYIRRQLEEEQRHLEVLQQQ 485
Query: 113 LAEEKA-----RREEEDAKRRAE 130
L +E+A R E + R+AE
Sbjct: 486 LLQEQAMLLECRWREMEEHRQAE 508
Score = 34.3 bits (77), Expect = 0.10
Identities = 44/180 (24%), Positives = 80/180 (44%), Gaps = 26/180 (14%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIP---EGEKVDFDDIQKKRQNKD 59
++E ++ E+ E + +EE EEEK R + I E E+ + +Q++ +
Sbjct: 431 EQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQ 490
Query: 60 LMELQAL---IDSHFEA----RKKEEEELVALKERIEKRRAE-RAEQQRIRAEKERERQN 111
M L+ ++ H +A R+ ++E+ L + + RR + QQ ++ER + +
Sbjct: 491 AMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPS 550
Query: 112 -RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 170
E KA E D R ED +K N+SS A++ KQT R ++ +
Sbjct: 551 FHAPEPKAHYEPADRAREVEDRFRK--------TNHSSPEAQS------KQTGRVLEPPV 596
Score = 30.0 bits (66), Expect = 2.0
Identities = 29/159 (18%), Positives = 64/159 (40%), Gaps = 3/159 (1%)
Query: 77 EEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKK 136
E + + LK+ I++ R +R E+ E + + E + ++
Sbjct: 295 ERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRR 354
Query: 137 KALSSMGANYSSYLAKADQKRGKKQTAREM---KKKILAERRKPLNIDHLGEDKLRDKAK 193
L N A Q+ ++Q RE K+++LAER+K + +L ++ +
Sbjct: 355 DFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQR 414
Query: 194 ELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 232
E Q E ++ ++ KR+ ++ R ++ ++
Sbjct: 415 REREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 59.3 bits (142), Expect = 3e-09
Identities = 51/215 (23%), Positives = 102/215 (47%), Gaps = 13/215 (6%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+ E+E +E +E E +++E + E++ R + K G+K +KK + K
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK------EKKGERKKEER 95
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREE 122
+ E ++ EE+E KE+ E+ R + ++R R E ER+R+ R E+ + E
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE-ERKREERKERERKKEER 154
Query: 123 EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDH 182
E + R E +KK+ +G K ++R K++ R+ +KK ER + +
Sbjct: 155 EKERERKE---RKKRERKQVGEKEEERKEKERKERKKRERNRKERKK---ERERKERRER 208
Query: 183 LGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 217
E K +++ K+ + Q + E G++ ++++
Sbjct: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
Score = 57.4 bits (137), Expect = 1e-08
Identities = 47/211 (22%), Positives = 97/211 (45%), Gaps = 14/211 (6%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 63
+E ++ E ++E + E+ +E EK R + K +GE+ + +KKR+ E
Sbjct: 49 KEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRR----EK 104
Query: 64 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEE 123
+ E RKK+E++ + R K ER ++ + E+ +ER+ + E + RE +
Sbjct: 105 ENKEGEEKEKRKKKEKKE---RGRTSKEGKERERKEERKREERKERERKKEEREKERERK 161
Query: 124 DAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHL 183
+ K+R + +K+ + ++K KK+ R+ +++ ER+K
Sbjct: 162 ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK------ 215
Query: 184 GEDKLRDKAKELWETLHQLEIDKFEFGEKLK 214
E++ +++ K+ + E K E E+ K
Sbjct: 216 -EERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 56.6 bits (135), Expect = 2e-08
Identities = 34/162 (20%), Positives = 85/162 (52%), Gaps = 2/162 (1%)
Query: 75 KKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLK 134
++ E E+ KE ++R +ER +++R R +++RER+ E+ ++E++ +++ E + K
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 135 KKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKE 194
K++ K +K+ + +T++E K++ E RK + ++ +++ ++
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK--REERKERERKKEEREK 156
Query: 195 LWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
E + + ++ + GEK + +K R + ++ +K KK
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198
Score = 50.1 bits (118), Expect = 2e-06
Identities = 35/130 (26%), Positives = 66/130 (50%), Gaps = 23/130 (17%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+ + E+ E+ +E E +EE E + E K R K ++ GEK ++ +K+++ K
Sbjct: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQV--GEK---EEERKEKERK---- 184
Query: 63 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQ-----NRLAEEK 117
E +K+E KER K R ER ++++ + E+++ERQ N +E+
Sbjct: 185 ---------ERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER 235
Query: 118 ARREEEDAKR 127
+RE ++ K+
Sbjct: 236 GKRERKERKK 245
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 58.9 bits (141), Expect = 4e-09
Identities = 50/173 (28%), Positives = 91/173 (52%), Gaps = 27/173 (15%)
Query: 5 EVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQ 64
EV+Q++ Q EE+ ++ E Q E + + + A K E E+++ R+ ++LME
Sbjct: 301 EVQQMKAQAREEKHQKQLERAQLENEKKKREIAEK--EKERIE-------REKEELMERL 351
Query: 65 ALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEED 124
I+ +KE EE + R+A +Q+R RA++E ER EK RR E+
Sbjct: 352 KQIEEQTIKAQKELEE--------QTRKALELDQERKRAKEEAERL-----EKERRAAEE 398
Query: 125 AK----RRAEDDLKKKKALSSMGANYSSYLAKADQ-KRGKKQTAREMKKKILA 172
AK ++A D +K ++ L++ A +++ +A ++ K+ K++ A E + K A
Sbjct: 399 AKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFA 451
Score = 50.4 bits (119), Expect = 1e-06
Identities = 51/183 (27%), Positives = 88/183 (48%), Gaps = 27/183 (14%)
Query: 52 QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAE------RAEQQRIRAEK 105
Q K Q ++ + L + E KK+ E KERIE+ + E + E+Q I+A+K
Sbjct: 304 QMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQK 363
Query: 106 ERERQNRLA---EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQT 162
E E Q R A +++ +R +E+A+R ++ ++A S++ ADQ + ++Q
Sbjct: 364 ELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQ------AADQMKNQEQL 417
Query: 163 AREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITT 222
A E LAE + L E+ + K +E E H+ F E L++ K ++ T
Sbjct: 418 AAE-----LAEFTAKI---ALLEEAKKKKEEEATEWQHK----AFAAQEDLEKTKEELKT 465
Query: 223 LRS 225
+ S
Sbjct: 466 VMS 468
Score = 33.9 bits (76), Expect = 0.14
Identities = 44/202 (21%), Positives = 80/202 (39%), Gaps = 17/202 (8%)
Query: 4 EEVEQVEEQYEEEEEAQEE--EEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLM 61
EE E++E++ EEA+ ++ ++ K + +L A K+ + KK++ ++
Sbjct: 384 EEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEAT 443
Query: 62 ELQALIDSHFEARKKEEEELVALKER---------IEKRRAERAEQQRIRAEKERERQNR 112
E Q + E +K +EEL + I E E AE E N
Sbjct: 444 EWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSNE 503
Query: 113 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 172
R EE+ + + + KK L ++ SS LA+A + K Q + + A
Sbjct: 504 GVMN--HRSEEERVTETQKNERVKKQLQAL----SSELAQARDETKKTQNDVLHAENVKA 557
Query: 173 ERRKPLNIDHLGEDKLRDKAKE 194
R K + + + + + E
Sbjct: 558 GRDKYKTLRQIRQGNTKQRIDE 579
Score = 32.7 bits (73), Expect = 0.30
Identities = 27/124 (21%), Positives = 60/124 (48%), Gaps = 12/124 (9%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 62
+ E E++ E+ ++ EE + + + EE+ R L + + K + + ++K+R+ + E
Sbjct: 341 EREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAE--E 398
Query: 63 LQALIDSHFEARKKEEEEL----------VALKERIEKRRAERAEQQRIRAEKERERQNR 112
++ I + K +E+L +AL E +K++ E A + + +A +E +
Sbjct: 399 AKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEK 458
Query: 113 LAEE 116
EE
Sbjct: 459 TKEE 462
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.125 0.329
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,931,556
Number of Sequences: 37866
Number of extensions: 541385
Number of successful extensions: 27785
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 951
Number of HSP's successfully gapped in prelim test: 985
Number of HSP's that attempted gapping in prelim test: 5894
Number of HSP's gapped (non-prelim): 9064
length of query: 250
length of database: 18,247,518
effective HSP length: 100
effective length of query: 150
effective length of database: 14,460,918
effective search space: 2169137700
effective search space used: 2169137700
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.