Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 112789538
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo
sapiens]
(256 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens] 504 e-143
gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] 478 e-135
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 478 e-135
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 459 e-129
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens] 322 2e-88
gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens] 320 8e-88
gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens] 312 2e-85
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 301 5e-82
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 300 8e-82
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 296 9e-81
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 295 3e-80
gi|148746195 trichohyalin [Homo sapiens] 70 2e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 69 3e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 67 1e-11
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 65 8e-11
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 64 2e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 63 2e-10
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 63 2e-10
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 63 3e-10
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 5e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 62 5e-10
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 62 6e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 61 8e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 59 5e-09
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 58 7e-09
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 58 7e-09
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 58 7e-09
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 58 7e-09
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 58 7e-09
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 58 7e-09
>gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens]
Length = 256
Score = 504 bits (1297), Expect = e-143
Identities = 256/256 (100%), Positives = 256/256 (100%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK 60
MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK 60
Query: 61 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 120
RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA
Sbjct: 61 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 120
Query: 121 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER
Sbjct: 121 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
Query: 181 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 240
RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS
Sbjct: 181 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 240
Query: 241 KKAGTPAKGKVGGRWK 256
KKAGTPAKGKVGGRWK
Sbjct: 241 KKAGTPAKGKVGGRWK 256
>gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
Length = 258
Score = 478 bits (1229), Expect = e-135
Identities = 249/259 (96%), Positives = 250/259 (96%), Gaps = 4/259 (1%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEP---EEKPRPKLTAPKIPEGEKVDFDDI 57
MSDEEVEQVEEQYEEEEEAQEE EV E+ E EEKPRPKLTAPKIPEGEKVDFDDI
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEE-EVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDI 59
Query: 58 QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN 117
QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN
Sbjct: 60 QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN 119
Query: 118 RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL 177
RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL
Sbjct: 120 RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL 179
Query: 178 AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 237
AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ
Sbjct: 180 AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 239
Query: 238 KHSKKAGTPAKGKVGGRWK 256
KHSKKAGTPAKGKVGGRWK
Sbjct: 240 KHSKKAGTPAKGKVGGRWK 258
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 478 bits (1229), Expect = e-135
Identities = 249/256 (97%), Positives = 249/256 (97%), Gaps = 6/256 (2%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK 60
MSDEEVEQVEEQYEEEEEAQEE EEV E EEKPRPKLTAPKIPEGEKVDFDDIQKK
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEE-----EEVQE-EEKPRPKLTAPKIPEGEKVDFDDIQKK 54
Query: 61 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 120
RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA
Sbjct: 55 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 114
Query: 121 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER
Sbjct: 115 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 174
Query: 181 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 240
RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS
Sbjct: 175 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 234
Query: 241 KKAGTPAKGKVGGRWK 256
KKAGTPAKGKVGGRWK
Sbjct: 235 KKAGTPAKGKVGGRWK 250
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 459 bits (1180), Expect = e-129
Identities = 239/256 (93%), Positives = 242/256 (94%), Gaps = 6/256 (2%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK 60
MSDEEVEQVEEQYEEEEEAQEE EEV E EEKPRPKLTAPKIPEGEKVDFDDIQKK
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEE-----EEVQE-EEKPRPKLTAPKIPEGEKVDFDDIQKK 54
Query: 61 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 120
RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA
Sbjct: 55 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 114
Query: 121 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER
Sbjct: 115 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 174
Query: 181 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 240
RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDI +R+R+ K S
Sbjct: 175 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIMNVRARVQMLAKFS 234
Query: 241 KKAGTPAKGKVGGRWK 256
KKAGTPAKGKVGGRWK
Sbjct: 235 KKAGTPAKGKVGGRWK 250
>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
Length = 262
Score = 322 bits (826), Expect = 2e-88
Identities = 170/265 (64%), Positives = 208/265 (78%), Gaps = 12/265 (4%)
Query: 1 MSDEEVEQVEEQYEEEE--EAQEEAAEVHEEVHEPEE-KPRPK------LTAPKIPEGEK 51
MSD E ++ EE+ EEE E +EEA E E V EPEE +P+P L PKIPEGE+
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
Query: 52 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 111
VDFDDI +KR KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EK
Sbjct: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
Query: 112 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 171
ERERQ +LAEEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT RE
Sbjct: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
Query: 172 MKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRS 231
MK +IL+ER+KPL+ID++GE++LR+KA+EL + +HQLE +KF+ KLK+QKY+I L +
Sbjct: 181 MKVRILSERKKPLDIDYMGEEQLREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYN 240
Query: 232 RIDQAQKHSKKAGTPAKGKVGGRWK 256
RI AQK K AG KG+VGGRWK
Sbjct: 241 RISHAQKFRKGAG---KGRVGGRWK 262
>gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens]
Length = 251
Score = 320 bits (820), Expect = 8e-88
Identities = 165/256 (64%), Positives = 202/256 (78%), Gaps = 5/256 (1%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK 60
MSD E ++ EE+ EEE A+EE E EE +P P L PKIPEGE+VDFDDI +K
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEE--EERPKPSRPVVPPLIPPKIPEGERVDFDDIHRK 58
Query: 61 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 120
R KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EKERERQ +LA
Sbjct: 59 RMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLA 118
Query: 121 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
EEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT REMK +IL+ER
Sbjct: 119 EEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSER 178
Query: 181 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 240
+KPL+ID++GE++LR+KA+EL + +HQLE +KF+ KLK+QKY+I L +RI AQK
Sbjct: 179 KKPLDIDYMGEEQLREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFR 238
Query: 241 KKAGTPAKGKVGGRWK 256
K AG KG+VGGRWK
Sbjct: 239 KGAG---KGRVGGRWK 251
>gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]
Length = 278
Score = 312 bits (799), Expect = 2e-85
Identities = 170/281 (60%), Positives = 208/281 (74%), Gaps = 28/281 (9%)
Query: 1 MSDEEVEQVEEQYEEEE--EAQEEAAEVHEEVHEPEE-KPRPK------LTAPKIPEGEK 51
MSD E ++ EE+ EEE E +EEA E E V EPEE +P+P L PKIPEGE+
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
Query: 52 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 111
VDFDDI +KR KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EK
Sbjct: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
Query: 112 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 171
ERERQ +LAEEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT RE
Sbjct: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
Query: 172 MKKKILAERRKPLNIDHLGEDKL----------------RDKAKELWETLHQLEIDKFEF 215
MK +IL+ER+KPL+ID++GE++L R+KA+EL + +HQLE +KF+
Sbjct: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
Query: 216 GEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 256
KLK+QKY+I L +RI AQK K AG KG+VGGRWK
Sbjct: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAG---KGRVGGRWK 278
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 301 bits (770), Expect = 5e-82
Identities = 161/268 (60%), Positives = 199/268 (74%), Gaps = 18/268 (6%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEE-----------KPR---PKLTAPKIPE 48
DE+ E EE E E E +E AE EE E +E KPR P L PKIP+
Sbjct: 32 DEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPD 91
Query: 49 GEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIR 108
GE+VDFDDI +KR KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR
Sbjct: 92 GERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIR 151
Query: 109 AEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQT 168
E+E+ERQNRLAEE+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ K ++K GK+QT
Sbjct: 152 NEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKTERKSGKRQT 210
Query: 169 AREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITT 228
RE KKKILAERRK L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I
Sbjct: 211 EREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINV 270
Query: 229 LRSRIDQAQKHSKKAGTPAKGKVGGRWK 256
LR+RI+ QK SK G K KV GRWK
Sbjct: 271 LRNRINDNQKVSKTRG---KAKVTGRWK 295
Score = 32.7 bits (73), Expect = 0.32
Identities = 17/71 (23%), Positives = 35/71 (49%)
Query: 73 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAK 132
I+ E ++EE+E A++E + R E +++ + E E + + EEE+AK
Sbjct: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAK 63
Query: 133 RRAEDDLKKKK 143
+ +++ K
Sbjct: 64 EAEDGPMEESK 74
Score = 32.0 bits (71), Expect = 0.54
Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
Query: 90 LKERIEKRRAERAEQQRIRAEKE----RERQNRLAEEKARREEEDAKRRAEDDLKKKKA 144
++E +E+ E E+ + E++ + Q AEE A E E + RAE+D ++++A
Sbjct: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 300 bits (768), Expect = 8e-82
Identities = 159/259 (61%), Positives = 200/259 (77%), Gaps = 9/259 (3%)
Query: 3 DEEVE-QVEEQYEEEEEAQEEAAEVHE-EVHEPEEKPR---PKLTAPKIPEGEKVDFDDI 57
D E E + EE EE+E +EEA E + + E + KPR P L PKIP+GE+VDFDDI
Sbjct: 31 DAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDI 90
Query: 58 QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN 117
+KR KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR E+E+ERQN
Sbjct: 91 HRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQN 150
Query: 118 RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL 177
RLAEE+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ K ++K GK+QT RE KKKIL
Sbjct: 151 RLAEERARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKTERKSGKRQTEREKKKKIL 209
Query: 178 AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 237
AERRK L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I LR+RI+ Q
Sbjct: 210 AERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQ 269
Query: 238 KHSKKAGTPAKGKVGGRWK 256
K SK G K KV GRWK
Sbjct: 270 KVSKTRG---KAKVTGRWK 285
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 296 bits (759), Expect = 9e-81
Identities = 162/274 (59%), Positives = 201/274 (73%), Gaps = 24/274 (8%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEE---------------KPR---PKLTAP 44
+EE E+ EE EE+ EA+ E E E E EE KPR P L P
Sbjct: 13 EEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPP 72
Query: 45 KIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQ 104
KIP+GE+VDFDDI +KR KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQ
Sbjct: 73 KIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQ 132
Query: 105 QRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKA--DQK 162
QRIR E+E+ERQNRLAEE+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ KA ++K
Sbjct: 133 QRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKAQTERK 191
Query: 163 RGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQ 222
GK+QT RE KKKILAERRK L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+Q
Sbjct: 192 SGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQ 251
Query: 223 KYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 256
KY+I LR+RI+ QK SK G K KV GRWK
Sbjct: 252 KYEINVLRNRINDNQKVSKTRG---KAKVTGRWK 282
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 295 bits (755), Expect = 3e-80
Identities = 159/262 (60%), Positives = 201/262 (76%), Gaps = 12/262 (4%)
Query: 3 DEEVE-QVEEQYEEEEEAQEEAAEVHE-EVHEPEEKPR---PKLTAPKIPEGEKVDFDDI 57
D E E + EE EE+E +EEA E + + E + KPR P L PKIP+GE+VDFDDI
Sbjct: 31 DAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDI 90
Query: 58 QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN 117
+KR KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR E+E+ERQN
Sbjct: 91 HRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQN 150
Query: 118 RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYL---AKADQKRGKKQTAREMKK 174
RLAEE+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ A+ ++K GK+QT RE KK
Sbjct: 151 RLAEERARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKQAQTERKSGKRQTEREKKK 209
Query: 175 KILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRID 234
KILAERRK L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I LR+RI+
Sbjct: 210 KILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRIN 269
Query: 235 QAQKHSKKAGTPAKGKVGGRWK 256
QK SK G K KV GRWK
Sbjct: 270 DNQKVSKTRG---KAKVTGRWK 288
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 69.7 bits (169), Expect = 2e-12
Identities = 66/254 (25%), Positives = 124/254 (48%), Gaps = 31/254 (12%)
Query: 7 EQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 66
+++E QY +EEE Q+E ++ E EPE++ R + + E E++ ++ Q R+ ++
Sbjct: 1074 QELERQYRKEEELQQEEEQLLRE--EPEKRRRQERER-QCREEEELQQEEEQLLREEREK 1130
Query: 67 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERERQNRLAEE-KA 124
Q L + E + ++EE L+E EKRR + E+Q R E ++E + L EE +
Sbjct: 1131 RRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK 1190
Query: 125 RREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQK------------------RGKK 166
RR+E + + R E++L+++K Y ++D K +G++
Sbjct: 1191 RRQERERQYREEEELQRQKRKQ----RYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 167 -QTAREMKKKILAERRKPLNIDH-LGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKY 224
+ R+++ L +R+ ++ H LGE + RD+ +E Q F E+L+R++
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQE--RRRWQQRDRHFPEEEQLEREEQ 1304
Query: 225 DITTLRSRIDQAQK 238
R R Q +K
Sbjct: 1305 KEAKRRDRKSQEEK 1318
Score = 67.0 bits (162), Expect = 2e-11
Identities = 57/234 (24%), Positives = 113/234 (48%), Gaps = 23/234 (9%)
Query: 14 EEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALI 73
+EEE+ QEE + E+ E EE+ R KL ++ + + Q+ R+ + L Q
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLR-KLERQELRRERQEEEQQQQRLRREQQLRRKQE-- 311
Query: 74 DSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARRE-----E 128
E R++++EE +ER E++ R +Q R E+ RE+Q R +E+ RRE E
Sbjct: 312 ----EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
Query: 129 EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDH 188
++ +RR + ++++ L + Q R ++Q RE + + + R+
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR------ 421
Query: 189 LGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 242
E +LR +E E H+ + ++ ++LKR++ + R ++ ++H ++
Sbjct: 422 --EQQLR---REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470
Score = 63.2 bits (152), Expect = 2e-10
Identities = 54/228 (23%), Positives = 116/228 (50%), Gaps = 13/228 (5%)
Query: 7 EQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 66
++ E++Y EEEE Q+E ++ E E + + K E ++ + ++++R+ + L
Sbjct: 984 QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL 1043
Query: 67 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE--EKA 124
E + E ++EEE+L+ +ER +RR E Q R E ++E + L E EK
Sbjct: 1044 QERERQYREE-EELQQEEEQLLG-EERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
Query: 125 RREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE----- 179
RR+E + + R E++L++++ + +++ +++ ++ ++++L E
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 180 RRKPLNIDHLGEDKLRDKAKEL----WETLHQLEIDKFEFGEKLKRQK 223
RR+ L + E++L+ + ++L E Q ++ E+L+RQK
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Score = 57.8 bits (138), Expect = 9e-09
Identities = 59/242 (24%), Positives = 125/242 (51%), Gaps = 26/242 (10%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDF--DDIQKK 60
++++ + ++ E++ +E+ E HE+ HE E + + K + E+ D+ + + +
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL----KREQEERRDWLKREEETE 465
Query: 61 RQNKDLMELQALIDSHFEARKK----EEEELVALKERIE---KRRAERAEQQRIRAEKER 113
R ++ + Q D E R++ EEEE +ER E +R E +QR++ ++E
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525
Query: 114 ER-QNRL-AEEKARREEED-----AKRRAEDDL---KKKKALSSMGANYSSYLAKADQKR 163
ER Q RL +E++ RRE+E+ KR E L ++++ L L K +++R
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
Query: 164 GKKQTAREMKKKILAERRKPLNIDHLGEDKLRDK--AKELWETLHQLEIDKFEFGEKLKR 221
+++ RE +++ L +R K ++ L +++ R++ +E E + ++ K E E+ ++
Sbjct: 586 RQQRLKREQEER-LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Query: 222 QK 223
Q+
Sbjct: 645 QQ 646
Score = 57.4 bits (137), Expect = 1e-08
Identities = 43/200 (21%), Positives = 99/200 (49%), Gaps = 4/200 (2%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
+E EQ E + ++ QEE E + E EE+ + +L + + E+ + + KR+
Sbjct: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 122
+ +E + +++ ++L+ +E ++R +R +++R+ +RE RL +E
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQE 613
Query: 123 KARREEEDAKRRAEDDLKKKKALSS--MGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
+ R E+ KR ++ ++++ L S L + Q+R +++ RE +++ L +R
Sbjct: 614 E--RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR 671
Query: 181 RKPLNIDHLGEDKLRDKAKE 200
K + + E +L ++ +E
Sbjct: 672 LKREHEEERREQELAEEEQE 691
Score = 56.6 bits (135), Expect = 2e-08
Identities = 48/236 (20%), Positives = 118/236 (50%), Gaps = 9/236 (3%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
+EE + +E+ E++E +E+ E E+ E++ R + + E E+ + +++ +
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 122
+ +L+ E + + E++L ++ +++ R +Q R + RE+Q R +E
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 123 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 182
+ R E++ + R E LK+++ + +Q+R K+Q R+ +++ R +
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE---RRER 487
Query: 183 PLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 238
L ++ E++ R++ + + L + + ++ E ++LKRQ+ + L+ R+ Q+
Sbjct: 488 WLKLE---EEERREQQERREQQLRREQEERRE--QRLKRQEEE-ERLQQRLRSEQQ 537
Score = 56.6 bits (135), Expect = 2e-08
Identities = 48/205 (23%), Positives = 96/205 (46%), Gaps = 17/205 (8%)
Query: 7 EQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 66
++ E QY +++E Q+E ++ + E EK R + + E E++ ++ Q + ++
Sbjct: 1014 QEWERQYRKKDELQQEEEQL---LREEREKRRLQERERQYREEEELQQEEEQLLGEERET 1070
Query: 67 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAE-----------KERER 115
Q L + + + ++EE L+E EKRR + E+Q E +ERE+
Sbjct: 1071 RRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREK 1130
Query: 116 QNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 175
+ R E+ REEE+ ++ E L+++ Y + + ++ ++Q RE ++K
Sbjct: 1131 RRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK 1190
Query: 176 ILAERRKPLNIDHLGEDKLRDKAKE 200
ER + + E+ R K K+
Sbjct: 1191 RRQERERQYREE---EELQRQKRKQ 1212
Score = 53.5 bits (127), Expect = 2e-07
Identities = 51/242 (21%), Positives = 119/242 (49%), Gaps = 17/242 (7%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHE-PEEKPRPKLTAPKIPEGEKVDFDDIQKKR 61
++E++ +EE EE+ + +E A ++ EE E++ R + + + + ++ +K+R
Sbjct: 828 EKELQFLEE--EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
Query: 62 QNKDLME--LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 119
++ + LQ + + ++EEEEL +ER ++RR E+ Q R + ++E + L
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEEL-QREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 120 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 179
EE+ +R ++ +R+ D K ++ + L + +KR + +E +KK E
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQL-------LGEEPEKRRR----QEREKKYREE 993
Query: 180 RRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKH 239
+ L ++ + ++ WE ++ + + + E+L R++ + L+ R Q ++
Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 240 SK 241
+
Sbjct: 1054 EE 1055
Score = 53.5 bits (127), Expect = 2e-07
Identities = 59/272 (21%), Positives = 120/272 (44%), Gaps = 28/272 (10%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK-RQ 62
EE Q+ Q E++ + + EE +E +L + + + ++++ R+
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER----AEQQRIRAEKERERQNR 118
K L E Q L E + +EEE+L E+ + RR ER E++++R E+E ++ R
Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766
Query: 119 -------LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGK------ 165
EE+ R+E E+ + R+++ +K + + + Q+ GK
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 166 KQTAREMKKKILAERRKPLNIDH--LGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 223
+ E ++++ ER + + ++K R + +ELW+ Q + E KL+ +
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE--RKLREEH 1884
Query: 224 YDITTLRSRIDQAQKHSKKAGTPA-KGKVGGR 254
+R + + Q+H + + +GK GR
Sbjct: 1885 -----IRRQQKEEQRHRQVGEIKSQEGKGHGR 1911
Score = 52.8 bits (125), Expect = 3e-07
Identities = 51/220 (23%), Positives = 114/220 (51%), Gaps = 19/220 (8%)
Query: 7 EQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 66
++ E QY ++++ Q++ ++ E EPE++ R + K E E++ ++ Q R+ ++
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGE--EPEKRRRQE-REKKYREEEELQQEEEQLLREEREK 1010
Query: 67 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERERQNRLAEEK-- 123
Q + + + ++EE L+E EKRR + E+Q R E ++E + L EE+
Sbjct: 1011 RRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERET 1070
Query: 124 ARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKP 183
RR+E + + R E++L++++ L + +KR +++ R+ +++ E +
Sbjct: 1071 RRRQELERQYRKEEELQQEE---------EQLLREEPEKRRRQERERQCREE---EELQQ 1118
Query: 184 LNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 223
L E++ + + +EL E ++ E + + E+L R++
Sbjct: 1119 EEEQLLREEREKRRRQEL-ERQYREEEEVQQEEEQLLREE 1157
Score = 52.0 bits (123), Expect = 5e-07
Identities = 60/242 (24%), Positives = 114/242 (47%), Gaps = 23/242 (9%)
Query: 10 EEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 69
+ ++ EEE+ ++E E E + K R + + E E+ +D Q+ R+ + +L
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Query: 70 QALIDSHFE-----ARKKEEEEL-------VALKERIEKRRAERAEQQR-IRAEKERERQ 116
+ D F +++EE++L L+E + RR ER +Q R R K RE +
Sbjct: 1614 RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEE 1673
Query: 117 NRL---AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQK---RGKKQTAR 170
L E++ RR+E D K R E+ +++ L + + + R ++Q +
Sbjct: 1674 QLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQ 1733
Query: 171 EMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLR 230
E +++ L + + I L E++LR + +E + L + E D+ E+ RQ+ + LR
Sbjct: 1734 ETEQEQLRRQERYRKI--LEEEQLRPEREE--QQLRRQERDRKFREEEQLRQEREEQQLR 1789
Query: 231 SR 232
S+
Sbjct: 1790 SQ 1791
Score = 51.2 bits (121), Expect = 9e-07
Identities = 49/249 (19%), Positives = 121/249 (48%), Gaps = 23/249 (9%)
Query: 3 DEEVEQVEEQY-------EEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFD 55
+EE E+ E++ ++EEE +E ++ EE +++ R + + E +
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERRE---- 516
Query: 56 DIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAE--RAEQQRIRAEKER 113
Q+ ++ ++ LQ + S + R+++EE L +R E++R E R EQ+ R ++
Sbjct: 517 --QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR--EQE 572
Query: 114 ERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMK 173
ER+++L + + R ++ KR E+ L+++ L + +Q+ +++ E +
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQR--LKREEVERLEQEERREQRLKREEPEEERR 630
Query: 174 KKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRI 233
+++L + + + +LR + +E E + E ++ ++LKR+ + +
Sbjct: 631 QQLLKSEEQ----EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686
Query: 234 DQAQKHSKK 242
++ Q+ +++
Sbjct: 687 EEEQEQARE 695
Score = 50.8 bits (120), Expect = 1e-06
Identities = 41/204 (20%), Positives = 97/204 (47%), Gaps = 9/204 (4%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTA-PKIPEGEKVDFDDIQKKRQ 62
+E E+ Q +EEE+ ++ + E E E+ R +L+A P + E + +++++
Sbjct: 749 QEEERAHRQQQEEEQRRDFTWQWQAE--EKSERGRQRLSARPPLREQRERQLRAEERQQR 806
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 122
+ + + + R++ E+EL L+E + +R ERA+Q + + +E Q R +
Sbjct: 807 EQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQ 866
Query: 123 KARREE------EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 176
+ RR++ E+ ++R L K AL L + +++ +++ + +++
Sbjct: 867 EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ 926
Query: 177 LAERRKPLNIDHLGEDKLRDKAKE 200
+ R+ + E LR++ ++
Sbjct: 927 ERQYREEEQLQQEEEQLLREEREK 950
Score = 50.1 bits (118), Expect = 2e-06
Identities = 48/215 (22%), Positives = 101/215 (46%), Gaps = 35/215 (16%)
Query: 7 EQVEEQYEEEEEAQEEAAEVHEEVHEP---EEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
++ E QY EEE+ Q+E ++ E E +E+ R K+ + E+ + +KR+
Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAE-------------RAEQQRIRAE 110
++ + + E + ++EE L+E EKRR + + E+Q +R E
Sbjct: 984 QEREK------KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 111 KER----ERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKK 166
+E+ ER+ + EE+ ++EE+ E + ++++ L Y + + ++ ++
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE------RQYRKEEELQQEEE 1091
Query: 167 QTAREMKKKILAERRKPLNIDHLGEDKLRDKAKEL 201
Q RE +K RR+ E++L+ + ++L
Sbjct: 1092 QLLREEPEK---RRRQERERQCREEEELQQEEEQL 1123
Score = 49.7 bits (117), Expect = 3e-06
Identities = 51/261 (19%), Positives = 119/261 (45%), Gaps = 33/261 (12%)
Query: 1 MSDEEVEQV------------EEQYEEEEEAQEEAAEVHEEVHEP---EEKPRPKLTAPK 45
+ +EE E E QY EEE+ Q+E ++ E E +E+ R K
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
Query: 46 IPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQ 105
+ + E+ + +KR+ ++ + E ++EEE + +ER ++RR E Q
Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREK-----KYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 106 RIRAEKERERQNRLAEEKARR--EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKR 163
R + E ++E + L EE+ +R +E + + R E++L++++ L + + R
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE---------EQLLGEERETR 1071
Query: 164 GKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEF--GEKLKR 221
+++ R+ +K+ ++ + + E + R + + +L+ ++ + E+ KR
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 222 QKYDITTLRSRIDQAQKHSKK 242
++ ++ ++ Q+ ++
Sbjct: 1132 RRQELERQYREEEEVQQEEEQ 1152
Score = 49.3 bits (116), Expect = 3e-06
Identities = 40/200 (20%), Positives = 95/200 (47%), Gaps = 12/200 (6%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
E+ E+ ++ + EEE +++ + E EE+ +L ++ E+ + + + KR+
Sbjct: 570 EQEERRDQLLKREEERRQQRLK-----REQEERLEQRLKREEVERLEQEERREQRLKREE 624
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERE-RQNRLAEE 122
+ Q L+ S + +++++ +ER E+R E++R+ +RE + R +E
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Query: 123 KARREEEDAKRRAEDDLKK--KKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
A E+E A+ R + + K + S A S ++ ++ G+++ + +K+ R
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR----R 740
Query: 181 RKPLNIDHLGEDKLRDKAKE 200
R+ + E++ + +E
Sbjct: 741 RRESELQWQEEERAHRQQQE 760
Score = 49.3 bits (116), Expect = 3e-06
Identities = 55/232 (23%), Positives = 107/232 (46%), Gaps = 48/232 (20%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
+EEV+Q EEQ EE + E+ + E EE + E E++ ++ +K+RQ
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ---------EEEQLLREEQEKRRQ 1193
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQR--IRAEKERERQNRLA 120
+ E + +EEEEL +R ++++ R E QR ++ + E E++N +
Sbjct: 1194 ER-------------ERQYREEEEL----QRQKRKQRYRDEDQRSDLKWQWEPEKENAVR 1236
Query: 121 EEKA---RREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL 177
+ K RE E ++ + L+ +++ + +L Q+R ++Q R +++
Sbjct: 1237 DNKVYCKGRENEQFRQLEDSQLRDRQSQQDL-----QHLLGEQQERDREQERRRWQQR-- 1289
Query: 178 AERRKP----LNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYD 225
+R P L + E K RD+ + + ++ + E EK +RQ+ D
Sbjct: 1290 -DRHFPEEEQLEREEQKEAKRRDRKSQ-----EEKQLLREEREEKRRRQETD 1335
Score = 49.3 bits (116), Expect = 3e-06
Identities = 53/248 (21%), Positives = 112/248 (45%), Gaps = 34/248 (13%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKR 61
S ++++ + + +E + QE + H PEE+ + + ++ ++ Q R
Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
Query: 62 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER-------------------A 102
+ ++ + D F +EEE+L+ +E RR ER
Sbjct: 1323 EEREEKRRRQETDRKF----REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
Query: 103 EQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQK 162
E+QR+R +ERER+ E++ R +E + + R + D K ++ + + +++
Sbjct: 1379 EEQRLR-RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437
Query: 163 RGKKQTAREMKKKILAERRKPLNIDH---LGEDKLRDKAKELWETLHQLEIDK--FEFGE 217
+ ++Q E ++K L E ++ H E++L + +E + LH+ E D+ E +
Sbjct: 1438 QVRRQ---ERERKFLEEEQQLRQERHRKFREEEQLLQEREE--QQLHRQERDRKFLEEEQ 1492
Query: 218 KLKRQKYD 225
+L+RQ+ D
Sbjct: 1493 QLRRQERD 1500
Score = 47.0 bits (110), Expect = 2e-05
Identities = 53/266 (19%), Positives = 114/266 (42%), Gaps = 43/266 (16%)
Query: 3 DEEVEQVEE----QYEEEEEAQEEAAEVHEEVHEPEEKPRPK----------------LT 42
+EE E++E+ ++EEE QE A E E+ E + PK +
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Query: 43 APKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKE-----------EEELVALK 91
P+ EG++ + +K+R+ + ++ Q +H + +++E EE+ +
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 92 ERIEKR-----------RAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLK 140
+R+ R RAE +Q+ R E E + + ++ RE+E E+ L+
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 141 KKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKE 200
+++ + +++R ++Q + + L E RK + L+++ ++
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901
Query: 201 LWETLHQLEID-KFEFGEKLKRQKYD 225
+ L + E + + E EK +RQ+ +
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQE 927
Score = 45.8 bits (107), Expect = 4e-05
Identities = 66/268 (24%), Positives = 114/268 (42%), Gaps = 56/268 (20%)
Query: 3 DEEVEQVEEQY--EEEEEAQEEAAEVHEEVHE----------PEEKPRPKLTAPKIPEGE 50
+EE++Q EEQ EE+E+ ++E + E E +E R L PE E
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232
Query: 51 KVDFDD-------------------IQKKRQNKDLMEL---QALIDSHFEARK------- 81
D+ ++ ++ +DL L Q D E R+
Sbjct: 1233 NAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRH 1292
Query: 82 -KEEEELVALKERIEKRRAERA--EQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDD 138
EEE+L +++ KRR ++ E+Q +R E+E +R+ + + K R EE+ + R E
Sbjct: 1293 FPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352
Query: 139 LKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKA 198
L++++ + Q++G+K E + + RK L E +LR +
Sbjct: 1353 LRRQERDRKFREEELRH-----QEQGRKFLEEEQRLRRQERERKFLK----EEQQLRCQE 1403
Query: 199 KELWETLHQLEIDKF-EFGEKLKRQKYD 225
+E + L Q KF E ++L RQ+ D
Sbjct: 1404 RE--QQLRQDRDRKFREEEQQLSRQERD 1429
Score = 42.7 bits (99), Expect = 3e-04
Identities = 60/241 (24%), Positives = 103/241 (42%), Gaps = 39/241 (16%)
Query: 4 EEVEQVEEQYEEE---EEAQEEAAEVHEEVHEPEE--KPRPKLTAPKIPEGEKVDFDDIQ 58
EE +QV Q E EE Q+ E H + E E+ + R + + K ++ Q
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ 1493
Query: 59 KKRQNKDLMELQALIDSHFEARKKEEEELVA---------LKERIEKRRAERAEQQRIRA 109
+RQ +D + + S RK EEE L+E + RR ER +Q+R
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR 1553
Query: 110 -----EKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRG 164
E+E+ RQ R E++ R+E D K R E+ +++ L + + G
Sbjct: 1554 DRKFREEEQLRQER-EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRR---QEG 1609
Query: 165 KKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDK--FEFGEKLKRQ 222
++Q +E +K + E L+++ + + LH+ E D+ E +L+RQ
Sbjct: 1610 QQQLRQERDRKFRED-----------EQLLQEREE---QQLHRQERDRKFLEEEPQLRRQ 1655
Query: 223 K 223
+
Sbjct: 1656 E 1656
Score = 42.4 bits (98), Expect = 4e-04
Identities = 61/267 (22%), Positives = 116/267 (43%), Gaps = 58/267 (21%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEG--------EKVDF 54
+E +EQ ++ E E QEE E + EPEE+ R +L + E E+ +
Sbjct: 595 EERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654
Query: 55 DDIQKKRQNKDLMELQALIDSHFEARKKEE---EELVALKERIEKR-------------- 97
+ + KR+ ++ Q L H E R+++E EE +ERI+ R
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Query: 98 -------RAERAEQQRIRAEKERERQNRLAE---------------EKARRE---EEDAK 132
R + E QR R E+E +R+ R +E E+ RR+ + A+
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAE 774
Query: 133 RRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQ------TAREMKKKILAERRKPLN- 185
++E ++ A + L +A++++ ++Q +E +++ ER K L
Sbjct: 775 EKSERGRQRLSARPPLREQRERQL-RAEERQQREQRFLPEEEEKEQRRRQRREREKELQF 833
Query: 186 IDHLGEDKLRDKAKELWETLHQLEIDK 212
++ + + R++A++L E L+ D+
Sbjct: 834 LEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Score = 41.2 bits (95), Expect = 9e-04
Identities = 52/248 (20%), Positives = 110/248 (44%), Gaps = 35/248 (14%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPK-----------IPEGEKV 52
EE + ++E+ E+ QE + EE +E+ R L + + E +++
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
Query: 53 DFDDIQKK-RQNKDLM---ELQALIDSHFEARKKEEEELVALKERIEK-----------R 97
+ +++ RQ++D E Q L + + +EEE+ V +ER K R
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
Query: 98 RAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLA 157
+ E++++ E+E ++ +R ++ EEE RR E D K ++ +L
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
Query: 158 KADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGE 217
+ ++Q R+ +++ + + L G+ + +D+ ++ E QL ++ E +
Sbjct: 1520 E------EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE-EQLRQEREE--Q 1570
Query: 218 KLKRQKYD 225
+L RQ+ D
Sbjct: 1571 QLSRQERD 1578
Score = 41.2 bits (95), Expect = 9e-04
Identities = 52/223 (23%), Positives = 101/223 (45%), Gaps = 30/223 (13%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKV--DFDDIQKKR 61
EE +Q+ Q + + QEE +E + + R + K E E++ + ++ Q R
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR----KFREEEQLRQEREEQQLSR 1574
Query: 62 QNKDL---MELQALIDSHFEARKKEEEELVALKERIEKRRAER----AEQQRIRAEKERE 114
Q +D +E Q + E + E+E+ + +E ++ R ER E +++ E+E +
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Query: 115 RQNRLAEEKARREEEDAKRRAEDD----------LKKKKALSSMGANYSSYLAKADQK-R 163
+ +R ++ EEE RR E + ++++ L G + D+K R
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR 1694
Query: 164 GKKQTAR--EMKKKILAE----RRKPLNIDHLGEDKLRDKAKE 200
++Q R E ++K L E RR+ L E++LR + ++
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
Score = 40.0 bits (92), Expect = 0.002
Identities = 38/209 (18%), Positives = 93/209 (44%), Gaps = 26/209 (12%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
D + ++++ +EE++ + E + E EP ++ R K + E + + Q++ +
Sbjct: 104 DGKESLLQDRRQEEDQRRFEPRDRQLE-EEPGQRRRQKRQEQERELAEGEEQSEKQERLE 162
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 122
+D R++ +EEL ++ ++R RAE++++++ K E + EE
Sbjct: 163 QRD--------------RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEE 208
Query: 123 KAR-----------REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 171
+ R REE+ +RR D ++ + L K ++K +++ R+
Sbjct: 209 QLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268
Query: 172 MKKKILAERRKPLNIDHLGEDKLRDKAKE 200
+ + E+ + L L ++ ++ ++
Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQ 297
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 69.3 bits (168), Expect = 3e-12
Identities = 57/248 (22%), Positives = 124/248 (50%), Gaps = 17/248 (6%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
+E++ + EE E+EE E E E + E+ + KI E EK + + RQ
Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 388
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERI---EKRRAERAEQQRIRAEKERERQNRL 119
+ + E + I E +++EE++ +E++ E+ E+ E+ R + EK RE++ ++
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 120 AEEKAR-REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 178
E++ + RE+E+ + E+ + +++ M + + ++ R +++ RE +KKI
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQE--GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE 506
Query: 179 ERRKPLNIDHLGEDKLRDKAKELWETLHQL---EIDKFEFGEKLKRQKYDI----TTLRS 231
+ K E+ ++++ +++WE ++ E E EK++RQ+ + LR
Sbjct: 507 QEEKIRE----QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQ 562
Query: 232 RIDQAQKH 239
+ ++ Q+H
Sbjct: 563 QEEKMQEH 570
Score = 60.8 bits (146), Expect = 1e-09
Identities = 54/243 (22%), Positives = 121/243 (49%), Gaps = 20/243 (8%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTA-----PKIPEGEKVDFD 55
++ ++ E++ Q E+ +E +E+ E E++ E EEK R + K+ E++ ++
Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341
Query: 56 DIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER 115
+K R+ ++ M Q I E R++EE+ ++E+ EKR+ + A+ R + EK RE+
Sbjct: 342 KEEKIRELEEKMHEQEKIREQEEKRQEEEK----IREQ-EKRQEQEAKMWR-QEEKIREQ 395
Query: 116 QNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 175
+ ++ E++ +E++ K +++ M + ++ R +++ RE +KK
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEE--------KMWEQEEEMQEQEEKMRRQEEKIREQEKK 447
Query: 176 ILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQ 235
I + K + + +++ +K E + + E E EK++RQ+ I +I +
Sbjct: 448 IREQEEKIREQEEMMQEQ-EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE 506
Query: 236 AQK 238
++
Sbjct: 507 QEE 509
Score = 54.3 bits (129), Expect = 1e-07
Identities = 36/152 (23%), Positives = 81/152 (53%), Gaps = 9/152 (5%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRP-----KLTAPKIPEGEKVDFD 55
M E+ E++ EQ E+ E +EE E E++ EEK R + KI E E++ +
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 464
Query: 56 DIQKK-RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER- 113
+K Q + E +A + E +++EE++ +++I ++ + EQ+ + E+E
Sbjct: 465 QEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 524
Query: 114 --ERQNRLAEEKARREEEDAKRRAEDDLKKKK 143
E++ ++ E++ + +E++ K R +++ +++
Sbjct: 525 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQ 556
Score = 52.4 bits (124), Expect = 4e-07
Identities = 56/261 (21%), Positives = 130/261 (49%), Gaps = 32/261 (12%)
Query: 1 MSDEEVEQVEEQYEEEEEAQE-EAAEVHEEVHEPEEK-PRPKLTAPKIPEGEKVDFDDIQ 58
++DEE+++ + +E+ + E E +E+ V E + K R KL P+ + + + D +
Sbjct: 202 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 259
Query: 59 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER 115
K+ Q+ +LQA ++ + +++EE++ +E+I++R + EQ+ +E+E
Sbjct: 260 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEE--KIREQEE 316
Query: 116 QNRLAEEKARREEEDAKRRAEDDLKKKKALSSM--GANYSSYLAKADQKRGKKQTAREMK 173
+ R EE +EE +R+ E +K++ + + + + + ++KR +++ RE +
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376
Query: 174 K-------------KILAERRKPLNIDHL---GEDKLRDKAKELWETLHQLEIDKFEFGE 217
K KI + K + + E+K+ ++ +++WE +++ E E
Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ----EQEE 432
Query: 218 KLKRQKYDITTLRSRIDQAQK 238
K++RQ+ I +I + ++
Sbjct: 433 KMRRQEEKIREQEKKIREQEE 453
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 67.4 bits (163), Expect = 1e-11
Identities = 61/251 (24%), Positives = 120/251 (47%), Gaps = 31/251 (12%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
E+ EQ++EQ E+ E +E+ E E++ EE ++ E EK + QK R
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE---------RLWEQEKQMREQEQKMRDQ 395
Query: 64 KDLMELQALIDSHFEARKKEEEEL--VALKERIEKRRAERAEQQRIRAEKERERQNRLAE 121
++ M Q E R +E+E++ K R EK+ E+ ++ R + EK +E +
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER 455
Query: 122 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERR 181
EK REEE+ R E+ ++K++ + + ++K ++Q E K+K+ + +
Sbjct: 456 EKKMREEEETMREQEEKMQKQE----------ENMWEQEEKEWQQQRLPEQKEKLWEQEK 505
Query: 182 KPLNIDHL--GEDKLRD------KAKELW--ETLHQLEIDKFEFGEKLKRQKYDITTLRS 231
+ + E+K+RD + K++W E + + E +E EK++ Q+ +
Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 565
Query: 232 RIDQAQKHSKK 242
R+++ + +K
Sbjct: 566 RMEKKTQEQEK 576
Score = 60.5 bits (145), Expect = 1e-09
Identities = 49/247 (19%), Positives = 126/247 (51%), Gaps = 16/247 (6%)
Query: 7 EQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 66
EQ E+ + +E+ +E+ E+ E+ E E+ + ++ E E+ ++ +K R+ ++
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370
Query: 67 M--ELQALIDSHFEARKKE------EEELVALKERIEKRRAERAEQQRIR--AEKERERQ 116
M + + L + + R++E EE + ER+ ++ EQ+++ EK RE +
Sbjct: 371 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEK 430
Query: 117 NRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 176
+EK R++E+ K + E+ +++++ M + + ++ + +++ E ++K
Sbjct: 431 KMQEQEKKTRDQEE-KMQEEERIRERE--KKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Query: 177 LAERRKPLNIDHLGE-DKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQ 235
++R P + L E +K++++ +++WE ++ + +G++ K + + +R + DQ
Sbjct: 488 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE--KMREQEDQ 545
Query: 236 AQKHSKK 242
+ +K
Sbjct: 546 MWEQEEK 552
Score = 60.5 bits (145), Expect = 1e-09
Identities = 42/226 (18%), Positives = 120/226 (53%), Gaps = 7/226 (3%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK 60
M D+E + +++ E++ QE+ + ++ + E+ R + K+ E E++ + +K
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 612
Query: 61 RQNKDLM-ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 119
++ ++ M E + + E +++EE++ +E++ ++ + EQQR+ +KE+ ++
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 672
Query: 120 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 179
+E+ + +E++ K ++ ++KK + + + R +++ RE +++++ E
Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMRE-EEEMMRE 731
Query: 180 RRKPLNIDHLGEDKLRDKAKELWETLHQL--EIDKFEFGEKLKRQK 223
+ + + E+K++++ +E+WE ++ + +K ++L QK
Sbjct: 732 QEEKMQEQ---EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Score = 59.7 bits (143), Expect = 2e-09
Identities = 45/243 (18%), Positives = 123/243 (50%), Gaps = 23/243 (9%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
+E + + +E+ E+EE E ++ E+V + E+ K+ E EK D +K ++
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEK-------KMQEQEKKTRDQEEKMQE 448
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER-ERQNRLAE 121
+ + E + + E +++EE++ +E + ++ + +QQR+ +KE+ Q ++ E
Sbjct: 449 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 508
Query: 122 EKARREEEDAKRRAEDDL--KKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 179
++ + E++ K R ++++ ++KK + + ++ R ++ E ++K+ +
Sbjct: 509 QEEKIWEQEEKIRDQEEMWGQEKK------------MWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 180 RRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKH 239
+K + + E K +++ K+ W+ ++ ++ E+ K+ + + +R + ++ Q+
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMR-EEERMREREKKMREEEEMMREQEEKMQEQ 615
Query: 240 SKK 242
+K
Sbjct: 616 EEK 618
Score = 55.8 bits (133), Expect = 3e-08
Identities = 49/251 (19%), Positives = 119/251 (47%), Gaps = 36/251 (14%)
Query: 3 DEEVEQVEEQYEEEEEA--QEEAAEVHEEVHEPEEKPRPK---------LTAPKIPEGEK 51
+E++ EE + +E++ QE+ E +++ E EEK R + K E EK
Sbjct: 517 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK 576
Query: 52 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 111
+D +K R+ + + E + + E +++EE++ +E+++++ + EQ+ EK
Sbjct: 577 KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE----EK 632
Query: 112 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 171
+E++ ++ E++ + E++ K + L ++K +K +++ +E
Sbjct: 633 MQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKE-----------KLWEHEKMQEQEKMQE 681
Query: 172 MKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRS 231
++KI + + E K +++ K+ W+ E + EK R++ ++ +R
Sbjct: 682 QEEKIWEQEKM--------EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM--MRE 731
Query: 232 RIDQAQKHSKK 242
+ ++ Q+ +K
Sbjct: 732 QEEKMQEQEEK 742
Score = 55.5 bits (132), Expect = 5e-08
Identities = 50/214 (23%), Positives = 106/214 (49%), Gaps = 23/214 (10%)
Query: 3 DEEVEQVEEQYEEEEEA---QEEAAEVHEE-VHEPEEK-----PRPKLTAPKIPEGEKVD 53
+E + + E++ EEEE QEE + EE + E EEK + + K+ E E+
Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647
Query: 54 FDDIQKKRQNKDLMELQALIDSH----FEARKKEEEELVALKERIEKRRAERAEQQRIRA 109
++ +K + + L E + + H + + +E+EE + +E++EK+ E+ E++
Sbjct: 648 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ-EKKTWDQ 706
Query: 110 EKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA 169
EK RE ++ EK REEE+ R E+ +++++ + ++ +++
Sbjct: 707 EKMREEESMREREKKMREEEEMMREQEEKMQEQE---------EKMQEQEEEMWEQEEKM 757
Query: 170 REMKKKILAERRKPLNIDHLGEDKLRDKAKELWE 203
E ++K+ ++R P + L E + + +++WE
Sbjct: 758 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWE 791
Score = 53.5 bits (127), Expect = 2e-07
Identities = 45/227 (19%), Positives = 110/227 (48%), Gaps = 7/227 (3%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
+ E Q +E+ +E+EE E ++ ++ E E+K + K+ E E + + + + +
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ---EKMREEESMREREKKMREE 725
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 122
+ + E + + E +++EEE+ +E++ ++ + EQQR+ +KE+ ++ +E
Sbjct: 726 EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE 785
Query: 123 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 182
+ + E++ K R +++ K + M + ++ G+++ ++K+ + K
Sbjct: 786 QEKIWEQEEKMRDQEE-KMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEK 844
Query: 183 PLNIDHLGEDKLR---DKAKELWETLHQLEIDKFEFGEKLKRQKYDI 226
+ E+K++ +K +E E + E E EK++ Q+ I
Sbjct: 845 MWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 50.8 bits (120), Expect = 1e-06
Identities = 52/236 (22%), Positives = 111/236 (47%), Gaps = 22/236 (9%)
Query: 10 EEQYEEEEEAQEEAAEVH---EEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 66
EE + +EEE +E+ ++ E++ EE+ R + + E EK+ + + + Q K+L
Sbjct: 272 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE-EKMWRQEKRLREQEKEL 330
Query: 67 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER----ERQNRLAEE 122
E + + E R++EE+ ++ E+ R +++++ ++ER E+Q R E+
Sbjct: 331 REQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 390
Query: 123 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 182
K R +EE R E D + ++ M + + KK +E K + E+ +
Sbjct: 391 KMRDQEE---RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Query: 183 PLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 238
E+++R++ K++ E + E EK+++Q+ ++ + Q Q+
Sbjct: 448 E-------EERIREREKKMREEEETMR----EQEEKMQKQEENMWEQEEKEWQQQR 492
Score = 48.5 bits (114), Expect = 6e-06
Identities = 49/229 (21%), Positives = 111/229 (48%), Gaps = 23/229 (10%)
Query: 11 EQYEEEEEAQEEAAEV--------HEEVHEPEEKPRPKLTAPKIPEGE-KVDFDDIQKKR 61
++Y EE + +A + +EE+ + + + KL + + E +++ ++++K
Sbjct: 196 DRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKL 255
Query: 62 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER-AEQQRIRAE--KERERQNR 118
+ + Q ++ E ++EEEL +++I K+ + +++R+R + K RE++ +
Sbjct: 256 ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEK 315
Query: 119 L-AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE---MKK 174
+ +EK RE+E R E +L+++K L K ++ K + E ++
Sbjct: 316 MWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 375
Query: 175 KILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 223
+ L E+ K + E K+RD+ + +WE +L E E+++ Q+
Sbjct: 376 ERLWEQEKQMREQ---EQKMRDQEERMWEQDERLR----EKEERMREQE 417
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 64.7 bits (156), Expect = 8e-11
Identities = 51/245 (20%), Positives = 118/245 (48%), Gaps = 19/245 (7%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
E+ EQ+ EQ E+ ++ +E+ E E++ + EE+ + E+V + Q ++Q
Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE--------QEEQVQKQEEQVQKQE 254
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERI--EKRRAERAEQQRIRAE--KERERQNRL 119
+ + + + + E +++EE+++ KE+ E++ E+ EQ R + E +E+E Q R
Sbjct: 255 EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMRE 314
Query: 120 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 179
EE+ R +EE ++ E ++K+ + + ++ + Q E +K +
Sbjct: 315 QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQ 374
Query: 180 RRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKH 239
RK E+++R + +++ + Q+ K + GE+ ++ + + + +Q +K
Sbjct: 375 MRKQ-------EEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQ 427
Query: 240 SKKAG 244
+ G
Sbjct: 428 EEHMG 432
Score = 60.5 bits (145), Expect = 1e-09
Identities = 46/204 (22%), Positives = 101/204 (49%), Gaps = 21/204 (10%)
Query: 3 DEEVEQVEEQYEEEEE----AQEEAAEVHEEVHEPEE-----KPRPKLTAPKIPEGEKVD 53
+E+V++ EEQ +++EE +E+ E E++ E EE K + + + E++
Sbjct: 240 EEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299
Query: 54 FDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER 113
+ Q + Q + + E + + E K+EE++ KE++ +++ + +Q+ E+E
Sbjct: 300 EQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEE 359
Query: 114 ERQNRLAEEKARREEEDAKRRAEDDLKK----KKALSSMGANYSSYLAKADQKRGKKQTA 169
+ Q + EE+ R++EE +++ E K+ +K MG + +Q R +++
Sbjct: 360 QMQKQ--EEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQM 417
Query: 170 REMKKKILAERRKPLNIDHLGEDK 193
E K+++ + +H+GE K
Sbjct: 418 GEQKEQMRKQE------EHMGEQK 435
Score = 55.8 bits (133), Expect = 3e-08
Identities = 47/242 (19%), Positives = 116/242 (47%), Gaps = 17/242 (7%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
E+ QV EQ + E + + E +V E E + R + EG+ + ++ +++
Sbjct: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEK 123
+ + + + + + R K+EE++ +E+++K+ + +Q E Q R EE+
Sbjct: 214 QMQKQEEQMGEQEEQMR-KQEEQMGEQEEQVQKQEEQVQKQ---------EEQMRKQEEQ 263
Query: 124 ARREEEDAKRRAEDDLKKKKAL---SSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
R +EE + + E LK+K+ G + +Q R +++ RE +++ + E+
Sbjct: 264 MREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ-MREQ 322
Query: 181 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 240
+ + E+++ ++ +++WE Q+ + + GE+ ++ + +R + +Q +K
Sbjct: 323 EEQMGKQ---EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379
Query: 241 KK 242
++
Sbjct: 380 EQ 381
Score = 42.7 bits (99), Expect = 3e-04
Identities = 31/136 (22%), Positives = 69/136 (50%), Gaps = 10/136 (7%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
+E++ + EEQ E+EE + E E E + + ++ + GE+ + Q ++Q
Sbjct: 309 EEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEE----QMQKQ 364
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 122
+ + + + + E +K+EE++ + E++ E+ EQ + E+ RE++ ++ E+
Sbjct: 365 EEQVRKQEEQMRKQEEQMRKQEEQM----RKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ 420
Query: 123 K--ARREEEDAKRRAE 136
K R++EE + E
Sbjct: 421 KEQMRKQEEHMGEQKE 436
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 63.5 bits (153), Expect = 2e-10
Identities = 57/222 (25%), Positives = 101/222 (45%), Gaps = 44/222 (19%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKR 61
+ E E+ +E+ E E+ +E E E + E+K R K K +++R
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGK------------ERER 77
Query: 62 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE 121
+ K+ E ++KE E K + EK++ ER ++ R +K++ER+ R E
Sbjct: 78 KRKER-----------EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERE 126
Query: 122 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERR 181
K RRE + KRR + K++ K +++RGK++ R+ +KK E++
Sbjct: 127 NKQRRERKRKKRRKKKRRKER---------------KREKERGKRERKRKKRKKEEREKK 171
Query: 182 KPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 223
+ N K R K +E E + + K E +K +R+K
Sbjct: 172 RERN------RKERKKERERKERRERKKERKKERRKKKERKK 207
Score = 52.4 bits (124), Expect = 4e-07
Identities = 47/163 (28%), Positives = 80/163 (49%), Gaps = 23/163 (14%)
Query: 80 RKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDL 139
++K E E +ER +K + +R +++R + E+ER+R+ R + K RRE+E KR+ E
Sbjct: 45 KRKREREKERKRERGKKEKKKRKKRERGK-ERERKRKEREKQRKERREKERRKRKKE--- 100
Query: 140 KKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAK 199
KKK+ G + ++K+ K++ RE + K ER++ K R K K
Sbjct: 101 KKKRERKQRG--------RRERKKKKERKERERENKQRRERKR----------KKRRKKK 142
Query: 200 ELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 242
E + E K E K KR+K + R R + +K ++
Sbjct: 143 RRKERKREKERGKRERKRK-KRKKEEREKKRERNRKERKKERE 184
Score = 49.7 bits (117), Expect = 3e-06
Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 4/142 (2%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
E ++ E + +E E+ ++E E + E+K R + + +K + + ++R+N
Sbjct: 70 ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE--REREN 127
Query: 64 KDLMELQALIDSHFEARK--KEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE 121
K E + + RK K E+E + + +KR+ E E++R R KER+++ E
Sbjct: 128 KQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKE 187
Query: 122 EKARREEEDAKRRAEDDLKKKK 143
+ R++E +RR + + KK +
Sbjct: 188 RRERKKERKKERRKKKERKKDR 209
Score = 41.6 bits (96), Expect = 7e-04
Identities = 34/152 (22%), Positives = 71/152 (46%), Gaps = 15/152 (9%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQ---- 58
+ E ++ E + + +E ++E + +E + E K R + K E ++ + ++ Q
Sbjct: 74 ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRER 133
Query: 59 ---KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER 115
K+R+ K E + + RK+++ + +++ E+ R ER +KERER
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKER--------KKERER 185
Query: 116 QNRLAEEKARREEEDAKRRAEDDLKKKKALSS 147
+ R +K R++E K+ + D K + S
Sbjct: 186 KERRERKKERKKERRKKKERKKDRKTDRQTDS 217
Score = 36.6 bits (83), Expect = 0.022
Identities = 26/133 (19%), Positives = 60/133 (45%)
Query: 110 EKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA 169
E ER+++ R E++ R E++ KR KKK+ G + +++R +++
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 170 REMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTL 229
K+K ++R+ K +++ + E + E + + +K +R++
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
Query: 230 RSRIDQAQKHSKK 242
R + ++ +K KK
Sbjct: 153 RGKRERKRKKRKK 165
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 63.2 bits (152), Expect = 2e-10
Identities = 49/247 (19%), Positives = 121/247 (48%), Gaps = 39/247 (15%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK 60
++ ++ E++ Q E+ +E +E+ E E++ E EEK R + K+ E++ ++ +K
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ--EEKMRRQEEMMWEKEEKM 351
Query: 61 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 120
R+ +++M + E ++ EE + +E+I + + EQ++IR ++E+ ++
Sbjct: 352 RRQEEMMWEKE------EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 405
Query: 121 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
E+ +R+E++AK +++ + R +++ RE +KK+ +
Sbjct: 406 REQEKRQEQEAKMWRQEE----------------------KIREQEEKIREQEKKMWRQE 443
Query: 181 RKPLNIDHLGEDKLRDKAKELWETLHQL--------EIDKFEFGEKLKRQKYDITTLRSR 232
K + + E++ R + +E+W ++ + +K EK+++Q+ + +
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503
Query: 233 I-DQAQK 238
+ DQ +K
Sbjct: 504 MHDQEEK 510
Score = 61.6 bits (148), Expect = 6e-10
Identities = 47/225 (20%), Positives = 108/225 (48%), Gaps = 28/225 (12%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
+E++ ++EE+ E+E+ +E+ + EE E++ R + A + EK+ + + + Q
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 435
Query: 63 NKDLMELQALIDSHFEARKKE----------EEELVALKERIEKRRAERAEQQRIRAEKE 112
K + + I + R++E +EE + +E I +++ + EQ++IR ++E
Sbjct: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEE 495
Query: 113 R-----------ERQNRLAEEKARREEEDAKRRAE---DDLKKKKALSSMGANYSSYLAK 158
+ E + R EEK R+EE + + E + +K + M + +
Sbjct: 496 KVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555
Query: 159 ADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWE 203
++K +++ R ++KI + K ++K+R++ +++WE
Sbjct: 556 QEEKMQEQEKMRRQEEKIREQEEKIRE----QKEKIREQEEKIWE 596
Score = 57.4 bits (137), Expect = 1e-08
Identities = 55/248 (22%), Positives = 124/248 (50%), Gaps = 40/248 (16%)
Query: 3 DEEVEQVEEQYEEEE----EAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQ 58
+E + + EE+ +E E +E+ + E + E EEK R K+ E EK+ + +
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRE--LEEKMHEQEKI--REQE 396
Query: 59 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQR--IRAEKERERQ 116
+KRQ ++ + Q E R+++E ++ +E+I ++ + EQ++ R E++ Q
Sbjct: 397 EKRQEEEKIREQ-------EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 449
Query: 117 NRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 176
++ EE+ R+E+E+ R+ E ++++ + + +K +++ R+ ++K+
Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEE------------IWRQKEKMHEQEKIRKQEEKV 497
Query: 177 LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQA 236
+ K H E+K+R++ +++W ++ E EK++ Q+ I R + +
Sbjct: 498 WRQEEKM----HDQEEKIREQEEKMWRQEEKIR----EQEEKIREQEEKI---REQEEMM 546
Query: 237 QKHSKKAG 244
Q+ +K G
Sbjct: 547 QEQEEKMG 554
Score = 52.8 bits (125), Expect = 3e-07
Identities = 42/204 (20%), Positives = 106/204 (51%), Gaps = 24/204 (11%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKI-PEGEKVDFDDIQKKRQ 62
EE+ + EE+ E+EE + ++HE+ +++ + K+ + EK+ + + RQ
Sbjct: 462 EEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQ 521
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKE--RERQNRLA 120
+ + E + I E +++EE + +E++ ++ + EQ+++R ++E RE++ ++
Sbjct: 522 EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIR 581
Query: 121 EEKAR-REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 179
E+K + RE+E+ E+ +++++ + Q++ +K +E K + E
Sbjct: 582 EQKEKIREQEEKIWEQEEKIREQEEMM--------------QEQEEKMWEQEEK---MCE 624
Query: 180 RRKPLNIDHLGEDKLRDKAKELWE 203
+ + + E+K+R + +++WE
Sbjct: 625 QEEKMQEQ---EEKMRRQEEKMWE 645
Score = 51.6 bits (122), Expect = 7e-07
Identities = 60/259 (23%), Positives = 132/259 (50%), Gaps = 44/259 (16%)
Query: 1 MSDEEVEQVEEQYEEEEEAQE-EAAEVHEEVHEPEEK-PRPKLTAPKIPEGEKVDFDDIQ 58
++DEE+++ + +E+ + E E +E+ V E + K R KL P+ + + + D +
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 271
Query: 59 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERE 114
K+ Q+ +LQA ++ + +++EE++ +E+I++ + EQ+ +IR ++E+
Sbjct: 272 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 115 RQNRLAEEKARREEE-----DAKRRAEDDL-----KKKKALSSM-------------GAN 151
R+ EEK RR+EE + K R ++++ +K + L M +
Sbjct: 331 REQ---EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
Query: 152 YSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHL--GEDKLRDKAKELW---ETLH 206
+ + ++KR +++ RE +K+ E + + + E+K+R++ K++W E +H
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 207 QLEIDKFEFGEKLKRQKYD 225
+ E + E+ KRQ+ +
Sbjct: 448 EQE----KIREEEKRQEQE 462
Score = 48.1 bits (113), Expect = 7e-06
Identities = 36/128 (28%), Positives = 72/128 (56%), Gaps = 13/128 (10%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK 60
M E+ E++ EQ EE+ + QE+ E++ E EEK R + KI E E+ ++ +K
Sbjct: 545 MMQEQEEKMGEQ-EEKMQEQEKMRRQEEKIREQEEKIREQ--KEKIREQEEKIWEQEEKI 601
Query: 61 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 120
R+ +++M+ Q E ++EE++ +E+++ E+ E+ R + EK E++ RL
Sbjct: 602 REQEEMMQEQE------EKMWEQEEKMCEQEEKMQ----EQEEKMRRQEEKMWEQEVRLR 651
Query: 121 EEKARREE 128
+++ + +E
Sbjct: 652 QQEEKMQE 659
Score = 43.1 bits (100), Expect = 2e-04
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
Query: 7 EQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 66
EQ E+ E+E+ ++E E++ E EEK R + KI E E+ ++ +K R+ +++
Sbjct: 555 EQEEKMQEQEKMRRQE-----EKIREQEEKIREQ--KEKIREQEEKIWEQEEKIREQEEM 607
Query: 67 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE 121
M+ Q E + E+EE + +E +R+ E+ +Q +R ++ E+ E
Sbjct: 608 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 32.7 bits (73), Expect = 0.32
Identities = 20/90 (22%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Query: 3 DEEVEQVEEQYEEEEEA---QEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQK 59
+E++ + +E+ E+EE QEE EE+ + +E+ + + EK+ + +
Sbjct: 577 EEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636
Query: 60 KRQNKDLMELQALIDSHFEARKKEEEELVA 89
+RQ + + E + + E ++ +E L A
Sbjct: 637 RRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 63.2 bits (152), Expect = 2e-10
Identities = 68/284 (23%), Positives = 129/284 (45%), Gaps = 53/284 (18%)
Query: 6 VEQVEEQYEEE-------EEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQ 58
VEQ+E+ EE E+ +E+ E E++ E + K + K+ ++ + +
Sbjct: 262 VEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDE 321
Query: 59 KKRQNKDLMELQALID--------------SHFEA-----RKKEEEELVALKERIEKRRA 99
++Q +L+ + L D + FEA R+++E+E+ L+ EK +
Sbjct: 322 NQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQD 381
Query: 100 ERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKA 159
+AEQ +RA++ +E +R E R+E+E+A+++ E + + +K+ A LA
Sbjct: 382 YQAEQDALRAKRNQEVADR---EWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAV- 437
Query: 160 DQKRGKKQTAREMKKKILAERRKPLNIDHLGEDK-----------LRDKAKELWETLHQL 208
+ Q R+ ++IL +R+ + + L E+K LR + +E + Q
Sbjct: 438 -----QVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQN 492
Query: 209 EIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS----KKAGTPAK 248
I FE G +LK + R RID+ ++ + G P K
Sbjct: 493 RIATFEEGRRLKE---EAQKRRERIDEIKRKKLEELRATGLPEK 533
Score = 40.8 bits (94), Expect = 0.001
Identities = 51/250 (20%), Positives = 116/250 (46%), Gaps = 51/250 (20%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEE---KPRPKLTAPKIPEGEKVDFDDI 57
++ EE+E ++ +++E+EA +A +++ + +E KL+ D +++
Sbjct: 119 LTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLS----------DLEEV 168
Query: 58 QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEK------RRAERAEQQRIRAEK 111
K+R Q L+ + R ++EEEL + + I R A+ E+Q+I+ E
Sbjct: 169 AKERA-------QNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKEL 221
Query: 112 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 171
+ E + RL + ++ +R+ E + K+++ ++ RG++Q +
Sbjct: 222 DTE-EKRLDQMMEVERQKSIQRQEELERKRRE----------------ERIRGRRQIVEQ 264
Query: 172 MKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRS 231
M+K + + L L E + ++K +++ E + QL+ + + E+ ++QK +
Sbjct: 265 MEKN---QEERSL----LAEQREQEK-EQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIK 316
Query: 232 RIDQAQKHSK 241
RI+ + K
Sbjct: 317 RINDENQKQK 326
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 62.8 bits (151), Expect = 3e-10
Identities = 56/231 (24%), Positives = 110/231 (47%), Gaps = 15/231 (6%)
Query: 10 EEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMEL 69
EE +EEE Q H E E E+K R + ++ E+ + K Q+K + +
Sbjct: 236 EEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEER----ERIKAEQDKKIADE 291
Query: 70 QALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER--ERQNRLAEEKARRE 127
+A I++ +A +E E + E+R R E++R E++R E + R AEE+ R +
Sbjct: 292 RARIEAEEKAAAQERE-----RREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIK 346
Query: 128 EEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNID 187
EE+ KR AE+ + K+ A A+A+++ K + + + K L E++ +
Sbjct: 347 EEE-KRAAEERQRIKE--EEKRAAEERQRARAEEEE-KAKVEEQKRNKQLEEKKHAMQET 402
Query: 188 HLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 238
+ +K+ K + W + + DK + K+ + T ++++ ++ Q+
Sbjct: 403 KIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQE 453
Score = 50.1 bits (118), Expect = 2e-06
Identities = 32/101 (31%), Positives = 60/101 (59%), Gaps = 6/101 (5%)
Query: 43 APKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERA 102
AP++ G++++ +++++R + E + L EA + EE LK++ E+RR
Sbjct: 527 APQVEAGKRLE--ELRRRRGETESEEFEKLKQKQQEAALELEE----LKKKREERRKVLE 580
Query: 103 EQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKK 143
E+++ R ++E +R+ R EEK R +EE +RRAE K++K
Sbjct: 581 EEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 621
Score = 49.7 bits (117), Expect = 3e-06
Identities = 59/240 (24%), Positives = 104/240 (43%), Gaps = 22/240 (9%)
Query: 18 EAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQK-KRQNKDLMELQALIDSH 76
EA+E+AA E E EE+ R + E EK ++ Q+ K + K E + I
Sbjct: 296 EAEEKAAAQERERREAEERERMR-------EEEKRAAEERQRIKEEEKRAAEERQRIKEE 348
Query: 77 FEARKKEEEELVALKER--IEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRR 134
E R EE + + +E+ E+R+ RAE++ +E++R +L E+K +E K
Sbjct: 349 -EKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGE 407
Query: 135 AEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKL 194
+ + K ++ A +K+G+ E K+ A+R K L EDK
Sbjct: 408 KVEQKIEGKWVNEKKAQEDKLQTAVLKKQGE-----EKGTKVQAKREK------LQEDKP 456
Query: 195 RDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGR 254
K +E+ + + + + E + +K T ++S+ + H K + GGR
Sbjct: 457 TFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGR 516
Score = 44.7 bits (104), Expect = 8e-05
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 25/134 (18%)
Query: 48 EGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRI 107
E E +F+ +++K+Q L EL+ E +KK EE L+E ++R+ E A++ ++
Sbjct: 545 ETESEEFEKLKQKQQEAAL-ELE-------ELKKKREERRKVLEEEEQRRKQEEADR-KL 595
Query: 108 RAEKERERQNRLAEEKARREEEDAKRRAE-------DDLKKKKALSSMGANY-----SSY 155
R E+E+ RL EE RR E A++R + DD K K + G++ + +
Sbjct: 596 REEEEK---RRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEF 652
Query: 156 LAKADQK-RGKKQT 168
L K+ QK G K T
Sbjct: 653 LNKSVQKSSGVKST 666
Score = 43.9 bits (102), Expect = 1e-04
Identities = 56/271 (20%), Positives = 118/271 (43%), Gaps = 38/271 (14%)
Query: 1 MSDEEVEQVEEQY---EEEEEAQEE----AAEVHEEVHEPEEKPRPKLTAPKIPEGE-KV 52
+ +EE EE+ EEE+ A EE AE E+ E+K +L K E K+
Sbjct: 345 IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKI 404
Query: 53 DFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKE 112
+ +++K + K + E +A D A K++ E EK +A++++++ +K
Sbjct: 405 KGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGE--------EKGTKVQAKREKLQEDKP 456
Query: 113 RERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYL---------------- 156
++ + +EK ++++E K + + +KK + + + ++
Sbjct: 457 TFKKEEIKDEKIKKDKE-PKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGG 515
Query: 157 -AKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFE- 214
A D K + E K++ RR+ + +KL+ K +E L +L+ + E
Sbjct: 516 RASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER 575
Query: 215 ---FGEKLKRQKYDITTLRSRIDQAQKHSKK 242
E+ +R+K + + R ++ ++ K+
Sbjct: 576 RKVLEEEEQRRKQEEADRKLREEEEKRRLKE 606
Score = 42.7 bits (99), Expect = 3e-04
Identities = 50/253 (19%), Positives = 107/253 (42%), Gaps = 45/253 (17%)
Query: 4 EEVEQVEEQYEEEE--EAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKR 61
EE E V + Y++ + +A+E E E+ E EEKP KR
Sbjct: 163 EETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKP----------------------KR 200
Query: 62 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE 121
+ +++ +++ +EE +++LK + E++R + E ++ E
Sbjct: 201 GSIGENQVEVMVEEK-TTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEE 259
Query: 122 E-KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
E K R E E A+ AE+ + K A+ D+K ++ E ++K A+
Sbjct: 260 EDKERAEAERARLEAEERERIK--------------AEQDKKIADERARIEAEEKAAAQE 305
Query: 181 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDK---FEFGEKLKRQKYDITTLRSRIDQAQ 237
R+ + +++R++ K E +++ ++ E +++K ++ R RI + +
Sbjct: 306 RERREAEE--RERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEE 363
Query: 238 KHSKKAGTPAKGK 250
K + + A+ +
Sbjct: 364 KRAAEERQRARAE 376
Score = 42.7 bits (99), Expect = 3e-04
Identities = 47/207 (22%), Positives = 89/207 (42%), Gaps = 37/207 (17%)
Query: 11 EQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQK-----KRQNKD 65
E+ + +A+ E + + + EE K+ K P+ E F D +K K QN +
Sbjct: 438 EEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGE 497
Query: 66 LMELQALIDSH----------FEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER 115
M + + + ++ E V +R+E+ R R E + EK +++
Sbjct: 498 FMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQK 557
Query: 116 QNRLA---EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREM 172
Q A EE ++ EE K E++ ++K+ +AD+K +++ R +
Sbjct: 558 QQEAALELEELKKKREERRKVLEEEEQRRKQ-------------EEADRKLREEEEKRRL 604
Query: 173 KKKI------LAERRKPLNIDHLGEDK 193
K++I AE+R+ + D L +DK
Sbjct: 605 KEEIERRRAEAAEKRQKMPEDGLSDDK 631
Score = 40.0 bits (92), Expect = 0.002
Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 24/100 (24%)
Query: 7 EQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 66
E E++E+ ++ Q+EAA EE+ + E+ R KV ++ Q+++Q +
Sbjct: 545 ETESEEFEKLKQKQQEAALELEELKKKREERR------------KVLEEEEQRRKQEE-- 590
Query: 67 MELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQR 106
+ + +EEEE LKE IE+RRAE AE+++
Sbjct: 591 ----------ADRKLREEEEKRRLKEEIERRRAEAAEKRQ 620
Score = 37.0 bits (84), Expect = 0.017
Identities = 41/199 (20%), Positives = 85/199 (42%), Gaps = 27/199 (13%)
Query: 78 EARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARRE--------EE 129
E R+++ EE+ ERI +R + E++ R + R RQ RL +++ E
Sbjct: 9 ELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEV 68
Query: 130 DAKRRAEDDLKKKKALSSM-----GANYSSYLAKADQKRGKK-QTAREMKKKI------- 176
+A+ D+ K ++ A + LA+ +++R K+ Q A E +K+
Sbjct: 69 NAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDA 128
Query: 177 ---LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRI 233
L RR + E++ +K ++ + EI++ E K ++ ++
Sbjct: 129 SLSLPSRRMQ---NDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKK 185
Query: 234 DQAQKHSKKAGTPAKGKVG 252
+ +K ++ P +G +G
Sbjct: 186 EDKEKEEEEEEKPKRGSIG 204
Score = 32.0 bits (71), Expect = 0.54
Identities = 18/58 (31%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Query: 92 ERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMG 149
ER + R ++ E+ R+ AE+ ++N EE+A RE +R ++ L++K+ S+G
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERR--RRARQERLRQKQEEESLG 60
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 62.0 bits (149), Expect = 5e-10
Identities = 51/250 (20%), Positives = 122/250 (48%), Gaps = 27/250 (10%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
+E++ ++EE+ E+E+ +E+ + EE E++ R + A + EK+ + + + Q
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
Query: 63 NKDLMELQALIDS----HFEARKKEEEELVALKERIEK-----RRAERAEQQRIRAEKER 113
K + + I E +++E+EE+ +E+I + R+ E+ +Q + K+
Sbjct: 450 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQE 509
Query: 114 ERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMK 173
E+ R EEK R +EE + + E ++++ + + ++ +++ +
Sbjct: 510 EKVWR-QEEKIREQEEKIREQEEKMWRQEEKI------------REQEEMWREEEKMHEQ 556
Query: 174 KKILAERRKPLNIDHL--GEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDITT 228
+KI E ++ D + E+K+R++ +++W E + + E + E EK+ +Q+ I
Sbjct: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE 616
Query: 229 LRSRIDQAQK 238
+I + ++
Sbjct: 617 QEEKIQEQEE 626
Score = 60.1 bits (144), Expect = 2e-09
Identities = 53/244 (21%), Positives = 121/244 (49%), Gaps = 30/244 (12%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
+E++ + EE+ E+EE E ++HE+ EE+ R + + EK+ + + RQ
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQ 589
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 122
+ + E + E R+++EE++ +E+I ++ + EQ+ EK RE++ ++ E+
Sbjct: 590 EEKIREQE-------EKRQEQEEKMWKQEEKIREQEEKIQEQE----EKIREQEEKIREQ 638
Query: 123 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 182
+ +E++ K E + K + M + + ++ R +++ RE ++KI +
Sbjct: 639 EEMTQEQEEK-MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ--- 694
Query: 183 PLNIDHLGEDKLRDKAKELWETLHQL---EIDKFEFGEKLKRQKYDI----TTLRSRIDQ 235
E+ ++++ +++WE ++ E E EK++RQ+ + LR + ++
Sbjct: 695 --------EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Query: 236 AQKH 239
Q+H
Sbjct: 747 MQEH 750
Score = 58.9 bits (141), Expect = 4e-09
Identities = 57/258 (22%), Positives = 125/258 (48%), Gaps = 34/258 (13%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEV---HEEVHEPEEKPRPK-----LTAPKIPEGEKVDFD 55
EE Q EE+ E+E+ QE+ A++ E++ E EEK R + KI E EK+ +
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 469
Query: 56 DIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAE-RAEQQRIRAEKERE 114
+ KRQ ++ M Q E + E+EE+ KE++ ++ + R +++++ ++E+
Sbjct: 470 E---KRQEQEEMWRQ-------EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI 519
Query: 115 RQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA----- 169
R+ EEK R +EE R+ E ++++ + ++KR +++
Sbjct: 520 REQ---EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 170 ---REMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDI 226
RE ++K+ + K E+K +++ +++W+ ++ + + E+ ++ +
Sbjct: 577 EKIREQEEKVWRQEEKIRE----QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 227 TTLRSRIDQAQKHSKKAG 244
+R + + Q+ +K G
Sbjct: 633 EKIREQEEMTQEQEEKMG 650
Score = 53.1 bits (126), Expect = 2e-07
Identities = 49/239 (20%), Positives = 114/239 (47%), Gaps = 32/239 (13%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTA-----PKIPEGEKVDFDDIQ 58
E+ E++ EQ E+ E +E+ E + E EEK R + K+ E++ ++ +
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 377
Query: 59 KKRQNKDLM--------ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAE 110
K R+ +++M EL+ + + R++EE+ K R +++R E+ + + E
Sbjct: 378 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 437
Query: 111 KERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAR 170
K RE++ ++ E++ + ++ K ++ +++++ + + ++K +++
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE-----QEEMWRQEEKIHEQEEIW 492
Query: 171 EMKKKILAERRKPLNIDHLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDI 226
K+K+ H E+K+R + +++W E + + E E EK+ RQ+ I
Sbjct: 493 RQKEKM-----------HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Score = 45.1 bits (105), Expect = 6e-05
Identities = 53/243 (21%), Positives = 119/243 (48%), Gaps = 30/243 (12%)
Query: 1 MSDEEVEQVEEQYEEEEEAQE-EAAEVHEEVHEPEEK-PRPKLTAPKIPEGEKVDFDDIQ 58
++DEE+++ + +E+ + E E +E+ V E + K R KL P+ + + + D +
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 271
Query: 59 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER 115
K+ Q+ +LQA ++ + +++EE++ +E+I++ + EQ+ EK RE+
Sbjct: 272 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE----EKIREQ 326
Query: 116 QNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 175
EEK R +EE +R+ E +K++ + + ++ +K+ +++
Sbjct: 327 -----EEKIREQEEKMRRQEEMMWEKEEK-----------MRRQEEMMWEKEEKMRRQEE 370
Query: 176 ILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQ 235
++ E+ + + + +K +EL E +H+ E K E+ ++++ I R +Q
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE--KIREQEEKRQEEEKIREQEKRQEQ 428
Query: 236 AQK 238
K
Sbjct: 429 EAK 431
Score = 45.1 bits (105), Expect = 6e-05
Identities = 44/211 (20%), Positives = 98/211 (46%), Gaps = 36/211 (17%)
Query: 1 MSDEEVEQVEEQYEEEEE----AQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDD 56
M ++E EE+ +E+E+ +E+ E E+V EEK R + EK +
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR--------EQEEKRQEQE 604
Query: 57 IQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQ 116
+ +Q + + E + I E +++EE++ +E +++ + EQ+ E+E + Q
Sbjct: 605 EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
Query: 117 NR----LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREM 172
+ +E+ RE+E R E+ +++++ + Q++ +K +E
Sbjct: 665 EQEETMWRQEEKIREQEKKIREQEEKIREQEEMM--------------QEQEEKMWEQEE 710
Query: 173 KKKILAERRKPLNIDHLGEDKLRDKAKELWE 203
K + E+ + + E+K+R + +++WE
Sbjct: 711 K---MCEQEEKMQEQ---EEKMRRQEEKMWE 735
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 62.0 bits (149), Expect = 5e-10
Identities = 56/256 (21%), Positives = 124/256 (48%), Gaps = 25/256 (9%)
Query: 7 EQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTA-----PKIPEGEKVDFDDIQKKR 61
E+++E E+ +E +E+ E E++ E EEK R + K+ E++ ++ +K R
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 427
Query: 62 QNKDLM--------ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER 113
+ +++M EL+ + + R++EE+ K R +++R E+ + + EK R
Sbjct: 428 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 487
Query: 114 ERQNRL--AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 171
E++ ++ EEK R+EE + + ++K+ + + ++ +K+ E
Sbjct: 488 EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE 547
Query: 172 MKKKILAERRKPLNID---HLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITT 228
++KI + K + H E+K+R++ +++W ++ E EK++ Q+ I
Sbjct: 548 QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR----EQEEKIREQEEKI-- 601
Query: 229 LRSRIDQAQKHSKKAG 244
R + + Q+ +K G
Sbjct: 602 -REQEEMTQEQEEKMG 616
Score = 60.1 bits (144), Expect = 2e-09
Identities = 51/238 (21%), Positives = 114/238 (47%), Gaps = 6/238 (2%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPE---EKPRPKLTAPKIPEGEKVDFDDIQKK 60
E+ E++ Q E E +E+ E+ E++HE E E+ + KI E EK + +
Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 480
Query: 61 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 120
RQ + + E + I E ++EE++ ++ E+ + + E+ + EK RE++
Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 121 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 180
+++ E+E+ R+ E+ + +++ M + ++ +++ RE ++KI +
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQE--EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Query: 181 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 238
K + + +++ +K E E + + E E EK++RQ+ I +I + ++
Sbjct: 599 EKIREQEEMTQEQ-EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/282 (19%), Positives = 132/282 (46%), Gaps = 43/282 (15%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
+E++ ++EE+ E+E+ +E+ + EE E++ R + A + EK+ + + + Q
Sbjct: 437 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 496
Query: 63 NKDLMELQALIDS----HFEARKKEEEELVALKERIEK-----RRAERAEQQRIRAEKER 113
+ + + I E +++E+EE+ +E+I + R+ E+ +Q + K+
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE 556
Query: 114 ERQNRL------AEEKAR-------------REEEDAKRRAEDDLKKKKALS-----SMG 149
E+ R EEK R RE+E+ R E+ +++++ ++ MG
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616
Query: 150 ANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHL---GEDKLRDKAKELWETLH 206
+ ++ + +++ R ++KI + +K + E+ ++++ +++WE
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 676
Query: 207 QL---EIDKFEFGEKLKRQKYDI----TTLRSRIDQAQKHSK 241
++ E E EK++RQ+ + LR + ++ Q+H +
Sbjct: 677 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 44.3 bits (103), Expect = 1e-04
Identities = 56/254 (22%), Positives = 122/254 (48%), Gaps = 32/254 (12%)
Query: 1 MSDEEVEQVEEQYEEEEEAQE-EAAEVHEEVHEPEEK-PRPKLTAPKIPEGEKVDFDDIQ 58
++DEE+++ + +E+ + E E +E+ V E + K R KL P+ + + + D +
Sbjct: 275 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 332
Query: 59 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER 115
K+ Q+ +LQA ++ + +++EE++ +E+I++ + EQ+ EK RE+
Sbjct: 333 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE----EKIREQ 387
Query: 116 QNRLAEEKARREEEDAKRRA----EDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 171
EEK R +EE +R+ E + K ++ M + + K++ RE
Sbjct: 388 -----EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 442
Query: 172 MKKKI-LAERRKPLNIDHLGEDKLRDKAK------ELWETLHQLEIDKFEFGEKLKRQKY 224
+++K+ E+ + E+K+R++ K ++W ++ E EK++ Q+
Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR----EQEEKIREQEE 498
Query: 225 DITTLRSRIDQAQK 238
+ +I + +K
Sbjct: 499 KMWRQEEKIHEQEK 512
Score = 31.6 bits (70), Expect = 0.71
Identities = 20/90 (22%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Query: 3 DEEVEQVEEQYEEEEEA---QEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQK 59
+E++ + EE+ E+E+ QEE EE+ + +E+ + + EK+ + +
Sbjct: 633 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 692
Query: 60 KRQNKDLMELQALIDSHFEARKKEEEELVA 89
+RQ + + E + + E ++ +E L A
Sbjct: 693 RRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 61.6 bits (148), Expect = 6e-10
Identities = 58/219 (26%), Positives = 104/219 (47%), Gaps = 39/219 (17%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
E+ E++ EQ E E +E E E + E EE+ R Q
Sbjct: 203 EQEERLREQEERLREQEERLCEQEERLREQEERLR----------------------EQE 240
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERI---EKRRAERAE-----QQRIRAEKER-- 113
+ L E + + H E ++EE L +ER+ E+R E+ E ++R+R ++ER
Sbjct: 241 ERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLC 300
Query: 114 ERQNRLAEEKARR-EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREM 172
E++ RL E++ R E+E+ R E+ L +++ L +Q+R +++ R +
Sbjct: 301 EQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLL 360
Query: 173 KKKILAERRKPLNIDHLGEDKLRDKAKELW--ETLHQLE 209
+++ L E + L L +++LR + + LW ETL +LE
Sbjct: 361 ERERLLEEVEEL----LEQERLRQQDERLWQQETLQELE 395
Score = 47.0 bits (110), Expect = 2e-05
Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 12/125 (9%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
E+ E++ EQ E E +E E E + E EE+ R + ++ E EK+ Q
Sbjct: 287 EQEERLREQEERLCEQEERLREQEERLCEQEERLREQ--EERLCEQEKLP-------GQE 337
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEK 123
+ L E++ L++ + R++EE+E + +ER+ + E EQ+R+R + ER Q +E
Sbjct: 338 RLLEEVEKLLE---QERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQEL 394
Query: 124 ARREE 128
R E
Sbjct: 395 ERLRE 399
Score = 42.7 bits (99), Expect = 3e-04
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 16/198 (8%)
Query: 43 APKIPEG-EKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER 101
AP+ P G KV+ Q + + L + + +A + + L L R E+R E+
Sbjct: 149 APEPPAGPSKVE----QLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQ 204
Query: 102 AEQQRIRAEKERERQNRLAEEKAR-REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKAD 160
E+ R + E+ RE++ RL E++ R RE+E+ R E+ L +++ + L + +
Sbjct: 205 EERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQE---ERLREHEERLCEQE 261
Query: 161 QKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLK 220
++ +++ +++ L E+ + L E++LR++ + L E +L E E+L
Sbjct: 262 ERLCEQEERLREQEERLHEQEERLCEQ---EERLREQEERLCEQEERLR----EQEERLC 314
Query: 221 RQKYDITTLRSRIDQAQK 238
Q+ + R+ + +K
Sbjct: 315 EQEERLREQEERLCEQEK 332
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 61.2 bits (147), Expect = 8e-10
Identities = 52/237 (21%), Positives = 119/237 (50%), Gaps = 30/237 (12%)
Query: 7 EQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDL 66
EQ E+ +E+ +E+ E+ E+ E E+ + + ++ E E+ ++ +K R+ ++
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Query: 67 M--ELQALIDSHFEARKKE------EEELVALKERIEKRRAERAEQQRIRAEKER-ERQN 117
M + + L + + R++E EE + ER+ ++ EQ+++ ++E+ + +
Sbjct: 333 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEE 392
Query: 118 RLAE-EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 176
R+ E EK REEE+ R E+ ++K++ + + ++K ++Q E K+K+
Sbjct: 393 RIREREKKMREEEETMREQEEKMQKQE----------ENMWEQEEKEWQQQRLPEQKEKL 442
Query: 177 LAERRKPLNIDHL--GEDKLRD------KAKELW--ETLHQLEIDKFEFGEKLKRQK 223
+ + + + E+K+RD + K++W E + + E +E EK++ Q+
Sbjct: 443 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
Score = 57.8 bits (138), Expect = 9e-09
Identities = 51/266 (19%), Positives = 132/266 (49%), Gaps = 28/266 (10%)
Query: 1 MSDEEV---EQVEEQYEEEEEAQEEAAEVHEE--VHEPEEKPRPKLTAPKIPEGEKVDFD 55
M D+E +Q E +E++E +E+ + E+ + + EEK R + K E EK +D
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREE---KKTQEQEKKTWD 551
Query: 56 DIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERI---EKRRAERAEQQRIRAEK- 111
+K R+ + + E + + E +++EE++ +E++ E++ E+ E+ + + EK
Sbjct: 552 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM 611
Query: 112 --------ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKR 163
E+E ++++ E++ E++ K + +++ K + M + ++ +
Sbjct: 612 WEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE-KMWEQEEKMREQEEKMREQEEKMQ 670
Query: 164 GKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQL--EIDKFEFGEKLKR 221
G+++ RE ++K+ + K E+K+R + +++W ++ + +K E+++
Sbjct: 671 GQEEKMREQEEKMQGQEEKMRE----QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMRE 726
Query: 222 QKYDITTLRSRI-DQAQKHSKKAGTP 246
++ I + ++ ++ +H ++ P
Sbjct: 727 KEERIRDQKEKMQERLPEHEERCSEP 752
Score = 57.4 bits (137), Expect = 1e-08
Identities = 50/259 (19%), Positives = 127/259 (49%), Gaps = 23/259 (8%)
Query: 3 DEEVEQVEEQYEEEEEA----QEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQ 58
+EE+ + E++ ++EE +E E ++ E EEK R + ++ E EK + +
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQ--EKRLREQEKELREQEK 297
Query: 59 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER----- 113
+ R+ K L E + + E ++EE++ +E++ ++ EQ++ E+E+
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 357
Query: 114 -----ERQNRLAEEKARREEEDAKRRAEDDLKKKKAL----SSMGANYSSYLAKADQKRG 164
E+ RL E++ R E++ E+ +++++ + M + + ++ +
Sbjct: 358 EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQK 417
Query: 165 KKQTAREMKKKILAERRKPLNIDHLGE-DKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 223
+++ E ++K ++R P + L E +K++++ +++WE ++ + +G++ K +
Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477
Query: 224 YDITTLRSRIDQAQKHSKK 242
+ +R + DQ + +K
Sbjct: 478 QE--KMREQEDQMWEQEEK 494
Score = 54.7 bits (130), Expect = 8e-08
Identities = 42/245 (17%), Positives = 117/245 (47%), Gaps = 8/245 (3%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
+ + + +E+ E+E+ QE+ ++ E+ + ++ K+ EK+ + Q Q
Sbjct: 433 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA--- 120
+ + + + + E +++E L +ER+ +++ +++++R EK+ + Q +
Sbjct: 493 EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Query: 121 EEKARREE---EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL 177
EEK R EE E K+ E++ ++ M + ++ +++ +E ++K+
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 612
Query: 178 AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 237
+ K + EDK++++ + +WE +++ + + E+ ++ + +R + ++ Q
Sbjct: 613 EQEEKMWEQEE--EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
Query: 238 KHSKK 242
+K
Sbjct: 671 GQEEK 675
Score = 53.9 bits (128), Expect = 1e-07
Identities = 50/251 (19%), Positives = 121/251 (48%), Gaps = 20/251 (7%)
Query: 1 MSDEEVEQVEEQYEEEEE-AQEEAAEVHEEVHEPEEK-PRPKLTAPKIPEGEKVDFDDIQ 58
+++EE+++ + +E+ A+ E +E+ V E + K R K P++ + +
Sbjct: 180 ITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQE----E 235
Query: 59 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKE---RER 115
RQ ++L E + I E ++EE L + ++ ++ + Q++ E+E RE+
Sbjct: 236 MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQ 295
Query: 116 QNRLAEEKARREEEDAKRRAEDDL-----KKKKALSSMGANYSSYLAKADQKRGKKQTAR 170
+ L E+K RE+E+ + E+ + K ++ M + Q R ++Q R
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 171 EMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLR 230
+ ++++ + + E+++R++ K +WE +++ ++ E+ K+ + + T+R
Sbjct: 356 DQEERMWEQDERLRE----KEERMREQEK-MWEQEEKMQ-EEERIREREKKMREEEETMR 409
Query: 231 SRIDQAQKHSK 241
+ ++ QK +
Sbjct: 410 EQEEKMQKQEE 420
Score = 49.3 bits (116), Expect = 3e-06
Identities = 46/249 (18%), Positives = 122/249 (48%), Gaps = 18/249 (7%)
Query: 1 MSDEEV--EQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQ 58
M +EE E+ ++ EEEE +E+ ++ ++ E+ + ++PE ++ ++ +
Sbjct: 388 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 447
Query: 59 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERI--EKRRAERAEQQRIRAEKERERQ 116
+ Q + + E E + +++EE+ ++++ +++ E+ +Q + EK R+++
Sbjct: 448 MQEQEEKIWEQ--------EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
Query: 117 NRLAEEKARREEEDAK-RRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMK-- 173
++ +++ R E+D + R E+ ++++K + K Q++ KK +E K
Sbjct: 500 QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE--EKKTQEQEKKTWDQEEKMR 557
Query: 174 -KKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSR 232
++ + ER K + + + +K +E E + + E +E EK++ Q+ + +
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
Query: 233 IDQAQKHSK 241
+ + ++ K
Sbjct: 618 MWEQEEEDK 626
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 58.5 bits (140), Expect = 5e-09
Identities = 59/241 (24%), Positives = 105/241 (43%), Gaps = 26/241 (10%)
Query: 6 VEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKP---RPKLTAPKIPEG--EKVDFDDIQKK 60
+E + +Y E A + ++ H + E+K R AP IP K D + I+ +
Sbjct: 211 IEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEME 270
Query: 61 RQNKDLM--ELQALIDSHF----EARKKEEEELVALKERIEKRRAERAEQQRIRAEKERE 114
+DL+ E+ D+H E KKE+E KER E+ R E++R E+ERE
Sbjct: 271 EDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERE 330
Query: 115 RQNRLAEEKARREEEDAKR-------------RAEDDLKKKKALSSMGANYSSYLAKADQ 161
R+ +EK R E + R R D + ++ S + S K+
Sbjct: 331 REREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRD 390
Query: 162 KRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKR 221
+ +++ RE +++ ER + + ++ R++ K+ + E D +E KL+R
Sbjct: 391 RERERERERERERERERERERERERER-EREREREREKDKKRDREEDEEDAYE-RRKLER 448
Query: 222 Q 222
+
Sbjct: 449 K 449
Score = 52.0 bits (123), Expect = 5e-07
Identities = 56/233 (24%), Positives = 96/233 (41%), Gaps = 17/233 (7%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 62
++E +++E++ E E +E E E E E + + + E E+ D K+R
Sbjct: 299 EKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERD 358
Query: 63 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 122
E D + + ++ K R +R ER ++ E+ERER+ E
Sbjct: 359 RDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERE 418
Query: 123 KAR-REEEDAKRR-----AEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 176
+ R RE E K+R ED +++K + ++Y Q+R K RE KK
Sbjct: 419 REREREREKDKKRDREEDEEDAYERRKLERKLREKEAAY-----QERLKNWEIRERKK-- 471
Query: 177 LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEID----KFEFGEKLKRQKYD 225
E K + ++ +AK L E L + D K+ G L+++ D
Sbjct: 472 TREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRD 524
Score = 50.1 bits (118), Expect = 2e-06
Identities = 37/136 (27%), Positives = 65/136 (47%), Gaps = 12/136 (8%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
++ + E++ E EEE + E A+ + + E E PK G +
Sbjct: 470 KKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQ---------- 519
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERI--EKRRAERAEQQRIRAEKERERQNRLAE 121
K L + + +++ RK+E+EEL +++R+ E AE QR+ E ER RQ ++ +
Sbjct: 520 KRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQ 579
Query: 122 EKARREEEDAKRRAED 137
E EEE+ K+ E+
Sbjct: 580 EPESEEEEEEKQEKEE 595
Score = 43.9 bits (102), Expect = 1e-04
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKP---RPKLTAPKIPEGEK-VDFDDIQ 58
++E E+ EE+ E + + E E+ + + P R ++ + EK ++ D+
Sbjct: 476 EKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERD 535
Query: 59 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 118
+KR+ ++L E++ + + E + EL +++ E+RR Q +I+ E E E +
Sbjct: 536 RKREKEELEEIRQRLLA--EGHPDPDAELQRMEQEAERRR-----QPQIKQEPESEEEEE 588
Query: 119 LAEEKARREEEDAKRRAEDDLK 140
+EK + EE + E + K
Sbjct: 589 EKQEKEEKREEPMEEEEEPEQK 610
Score = 34.7 bits (78), Expect = 0.083
Identities = 18/43 (41%), Positives = 26/43 (60%), Gaps = 6/43 (13%)
Query: 10 EEQYEEEEEAQEEAAEVHEEVHEPEEKP------RPKLTAPKI 46
EE+ EE++E +E+ E EE EPE+KP RP +AP +
Sbjct: 584 EEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSV 626
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 58.2 bits (139), Expect = 7e-09
Identities = 61/266 (22%), Positives = 120/266 (45%), Gaps = 20/266 (7%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPR--PKLTAPKIPEGEKVDFDD--- 56
++ ++ EE+ + +EE + + E+ E E K R +L K E + +
Sbjct: 738 AEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIA 797
Query: 57 IQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQ 116
++++R+ ++ + + + E R++EEEE +E + K+ E A+ A +E E Q
Sbjct: 798 LRRQREEEERQQQEEAL-RRLEERRREEEERRKQEELLRKQEEEAAKW----AREEEEAQ 852
Query: 117 NRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 176
RL E + R EEE A+ R E++ +K+K L + + Q+ ++ ++ +++
Sbjct: 853 RRLEENRLRMEEEAARLRHEEEERKRKEL-EVQRQKELMRQRQQQQEALRRLQQQQQQQQ 911
Query: 177 LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFE------FGEKLKRQKYDITTLR 230
LA+ + P + + A + TL EI K E E+ +RQ+ ++
Sbjct: 912 LAQMKLPSS--STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 969
Query: 231 SRIDQAQKHSKKAGTPAKGKVGGRWK 256
+ Q Q+ K +G K G K
Sbjct: 970 QQ-QQQQQQQKLSGWGNVSKPSGTTK 994
Score = 53.5 bits (127), Expect = 2e-07
Identities = 39/184 (21%), Positives = 96/184 (52%), Gaps = 11/184 (5%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
E+++Q+E+ + E + AE+ + E E K + +L + E + ++ +K+R+
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ-EEILRRQQEEERKRREE 776
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER--ERQNRLAE 121
++L + EA +++ E+ +AL+ + E+ ++ E+ R E+ R E + R E
Sbjct: 777 EELARRK-----QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 831
Query: 122 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAK---ADQKRGKKQTAREMKKKILA 178
E R++EE+A + A ++ + ++ L A+ +++R +K+ + +K+++
Sbjct: 832 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 891
Query: 179 ERRK 182
+R++
Sbjct: 892 QRQQ 895
Score = 52.8 bits (125), Expect = 3e-07
Identities = 49/195 (25%), Positives = 91/195 (46%), Gaps = 18/195 (9%)
Query: 38 RPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKR 97
+P + P + EG V + L +LQ L + +A K E+E R +
Sbjct: 689 QPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKA--KAAKLEQER------REAEM 740
Query: 98 RAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLA 157
RA+R E++R R E+ R +Q + R++EE+ KRR E++L ++K ++ +A
Sbjct: 741 RAKREEEERKRQEELRRQQEEILR---RQQEEERKRREEEELARRKQEEALRRQREQEIA 797
Query: 158 KADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDK-------AKELWETLHQLEI 210
Q+ +++ +E + L ERR+ E+ LR + A+E E +LE
Sbjct: 798 LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE 857
Query: 211 DKFEFGEKLKRQKYD 225
++ E+ R +++
Sbjct: 858 NRLRMEEEAARLRHE 872
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/208 (22%), Positives = 98/208 (47%), Gaps = 17/208 (8%)
Query: 44 PKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKE----EEELVALKERIEKRRA 99
P + + ++++ K Q + E++A + R++E +EE++ ++ E++R
Sbjct: 715 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 774
Query: 100 ERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDD----LKKKKALSSMGANYSSY 155
E E R R ++E R+ R E RR+ E+ +R+ +++ L++++
Sbjct: 775 EEEELAR-RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 833
Query: 156 LAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEF 215
L K +++ K ARE ++ A+RR N + E+ R + +E +LE+ +
Sbjct: 834 LRKQEEEAAK--WAREEEE---AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR--- 885
Query: 216 GEKLKRQKYDITTLRSRIDQAQKHSKKA 243
++L RQ+ R+ Q Q+ + A
Sbjct: 886 QKELMRQRQQQQEALRRLQQQQQQQQLA 913
Score = 39.7 bits (91), Expect = 0.003
Identities = 46/218 (21%), Positives = 92/218 (42%), Gaps = 45/218 (20%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDF----DDIQ 58
++E+ ++ EEE + QEEA EE EE+ R + + E E + ++ Q
Sbjct: 793 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 852
Query: 59 KK-RQNKDLMELQALIDSHFEA-RKKEEEELVALKERIEKRRAERAEQQRIRAEK----- 111
++ +N+ ME +A H E RK++E E+ KE + +R+ ++ +R++ ++
Sbjct: 853 RRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQL 912
Query: 112 ----------------------------------ERERQNRLAEEKARREEEDAKRRAED 137
E ER+ +L EE+ R++ E K +
Sbjct: 913 AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ 972
Query: 138 DLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 175
++++ LS G +++ AR+M+K+
Sbjct: 973 QQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
Score = 30.8 bits (68), Expect = 1.2
Identities = 27/126 (21%), Positives = 49/126 (38%), Gaps = 16/126 (12%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
EE E +E EE + +EE EP++ + EGEK D ++ +
Sbjct: 313 EEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNK--------KEGEKTDRVGVEASEET 364
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEK 123
A + + + +E + +R+ E +Q +AE+E +N L +
Sbjct: 365 PQTSSSSARPGTPSDHQSQEASQF--------ERKDEPKTEQTEKAEEETRMENSLPAKV 416
Query: 124 ARREEE 129
R +E
Sbjct: 417 PSRGDE 422
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 58.2 bits (139), Expect = 7e-09
Identities = 61/266 (22%), Positives = 120/266 (45%), Gaps = 20/266 (7%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPR--PKLTAPKIPEGEKVDFDD--- 56
++ ++ EE+ + +EE + + E+ E E K R +L K E + +
Sbjct: 765 AEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIA 824
Query: 57 IQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQ 116
++++R+ ++ + + + E R++EEEE +E + K+ E A+ A +E E Q
Sbjct: 825 LRRQREEEERQQQEEAL-RRLEERRREEEERRKQEELLRKQEEEAAKW----AREEEEAQ 879
Query: 117 NRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 176
RL E + R EEE A+ R E++ +K+K L + + Q+ ++ ++ +++
Sbjct: 880 RRLEENRLRMEEEAARLRHEEEERKRKEL-EVQRQKELMRQRQQQQEALRRLQQQQQQQQ 938
Query: 177 LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFE------FGEKLKRQKYDITTLR 230
LA+ + P + + A + TL EI K E E+ +RQ+ ++
Sbjct: 939 LAQMKLPSS--STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 996
Query: 231 SRIDQAQKHSKKAGTPAKGKVGGRWK 256
+ Q Q+ K +G K G K
Sbjct: 997 QQ-QQQQQQQKLSGWGNVSKPSGTTK 1021
Score = 53.5 bits (127), Expect = 2e-07
Identities = 39/184 (21%), Positives = 96/184 (52%), Gaps = 11/184 (5%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
E+++Q+E+ + E + AE+ + E E K + +L + E + ++ +K+R+
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ-EEILRRQQEEERKRREE 803
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER--ERQNRLAE 121
++L + EA +++ E+ +AL+ + E+ ++ E+ R E+ R E + R E
Sbjct: 804 EELARRK-----QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 858
Query: 122 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAK---ADQKRGKKQTAREMKKKILA 178
E R++EE+A + A ++ + ++ L A+ +++R +K+ + +K+++
Sbjct: 859 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 918
Query: 179 ERRK 182
+R++
Sbjct: 919 QRQQ 922
Score = 52.8 bits (125), Expect = 3e-07
Identities = 49/195 (25%), Positives = 91/195 (46%), Gaps = 18/195 (9%)
Query: 38 RPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKR 97
+P + P + EG V + L +LQ L + +A K E+E R +
Sbjct: 716 QPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKA--KAAKLEQER------REAEM 767
Query: 98 RAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLA 157
RA+R E++R R E+ R +Q + R++EE+ KRR E++L ++K ++ +A
Sbjct: 768 RAKREEEERKRQEELRRQQEEILR---RQQEEERKRREEEELARRKQEEALRRQREQEIA 824
Query: 158 KADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDK-------AKELWETLHQLEI 210
Q+ +++ +E + L ERR+ E+ LR + A+E E +LE
Sbjct: 825 LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE 884
Query: 211 DKFEFGEKLKRQKYD 225
++ E+ R +++
Sbjct: 885 NRLRMEEEAARLRHE 899
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/208 (22%), Positives = 98/208 (47%), Gaps = 17/208 (8%)
Query: 44 PKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKE----EEELVALKERIEKRRA 99
P + + ++++ K Q + E++A + R++E +EE++ ++ E++R
Sbjct: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
Query: 100 ERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDD----LKKKKALSSMGANYSSY 155
E E R R ++E R+ R E RR+ E+ +R+ +++ L++++
Sbjct: 802 EEEELAR-RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 860
Query: 156 LAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEF 215
L K +++ K ARE ++ A+RR N + E+ R + +E +LE+ +
Sbjct: 861 LRKQEEEAAK--WAREEEE---AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR--- 912
Query: 216 GEKLKRQKYDITTLRSRIDQAQKHSKKA 243
++L RQ+ R+ Q Q+ + A
Sbjct: 913 QKELMRQRQQQQEALRRLQQQQQQQQLA 940
Score = 39.7 bits (91), Expect = 0.003
Identities = 46/218 (21%), Positives = 92/218 (42%), Gaps = 45/218 (20%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDF----DDIQ 58
++E+ ++ EEE + QEEA EE EE+ R + + E E + ++ Q
Sbjct: 820 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 879
Query: 59 KK-RQNKDLMELQALIDSHFEA-RKKEEEELVALKERIEKRRAERAEQQRIRAEK----- 111
++ +N+ ME +A H E RK++E E+ KE + +R+ ++ +R++ ++
Sbjct: 880 RRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQL 939
Query: 112 ----------------------------------ERERQNRLAEEKARREEEDAKRRAED 137
E ER+ +L EE+ R++ E K +
Sbjct: 940 AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ 999
Query: 138 DLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 175
++++ LS G +++ AR+M+K+
Sbjct: 1000 QQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1037
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 58.2 bits (139), Expect = 7e-09
Identities = 61/266 (22%), Positives = 120/266 (45%), Gaps = 20/266 (7%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPR--PKLTAPKIPEGEKVDFDD--- 56
++ ++ EE+ + +EE + + E+ E E K R +L K E + +
Sbjct: 744 AEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIA 803
Query: 57 IQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQ 116
++++R+ ++ + + + E R++EEEE +E + K+ E A+ A +E E Q
Sbjct: 804 LRRQREEEERQQQEEAL-RRLEERRREEEERRKQEELLRKQEEEAAKW----AREEEEAQ 858
Query: 117 NRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 176
RL E + R EEE A+ R E++ +K+K L + + Q+ ++ ++ +++
Sbjct: 859 RRLEENRLRMEEEAARLRHEEEERKRKEL-EVQRQKELMRQRQQQQEALRRLQQQQQQQQ 917
Query: 177 LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFE------FGEKLKRQKYDITTLR 230
LA+ + P + + A + TL EI K E E+ +RQ+ ++
Sbjct: 918 LAQMKLPSS--STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 975
Query: 231 SRIDQAQKHSKKAGTPAKGKVGGRWK 256
+ Q Q+ K +G K G K
Sbjct: 976 QQ-QQQQQQQKLSGWGNVSKPSGTTK 1000
Score = 53.5 bits (127), Expect = 2e-07
Identities = 39/184 (21%), Positives = 96/184 (52%), Gaps = 11/184 (5%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
E+++Q+E+ + E + AE+ + E E K + +L + E + ++ +K+R+
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ-EEILRRQQEEERKRREE 782
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER--ERQNRLAE 121
++L + EA +++ E+ +AL+ + E+ ++ E+ R E+ R E + R E
Sbjct: 783 EELARRK-----QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 837
Query: 122 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAK---ADQKRGKKQTAREMKKKILA 178
E R++EE+A + A ++ + ++ L A+ +++R +K+ + +K+++
Sbjct: 838 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897
Query: 179 ERRK 182
+R++
Sbjct: 898 QRQQ 901
Score = 52.8 bits (125), Expect = 3e-07
Identities = 49/195 (25%), Positives = 91/195 (46%), Gaps = 18/195 (9%)
Query: 38 RPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKR 97
+P + P + EG V + L +LQ L + +A K E+E R +
Sbjct: 695 QPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKA--KAAKLEQER------REAEM 746
Query: 98 RAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLA 157
RA+R E++R R E+ R +Q + R++EE+ KRR E++L ++K ++ +A
Sbjct: 747 RAKREEEERKRQEELRRQQEEILR---RQQEEERKRREEEELARRKQEEALRRQREQEIA 803
Query: 158 KADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDK-------AKELWETLHQLEI 210
Q+ +++ +E + L ERR+ E+ LR + A+E E +LE
Sbjct: 804 LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE 863
Query: 211 DKFEFGEKLKRQKYD 225
++ E+ R +++
Sbjct: 864 NRLRMEEEAARLRHE 878
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/208 (22%), Positives = 98/208 (47%), Gaps = 17/208 (8%)
Query: 44 PKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKE----EEELVALKERIEKRRA 99
P + + ++++ K Q + E++A + R++E +EE++ ++ E++R
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
Query: 100 ERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDD----LKKKKALSSMGANYSSY 155
E E R R ++E R+ R E RR+ E+ +R+ +++ L++++
Sbjct: 781 EEEELAR-RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839
Query: 156 LAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEF 215
L K +++ K ARE ++ A+RR N + E+ R + +E +LE+ +
Sbjct: 840 LRKQEEEAAK--WAREEEE---AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR--- 891
Query: 216 GEKLKRQKYDITTLRSRIDQAQKHSKKA 243
++L RQ+ R+ Q Q+ + A
Sbjct: 892 QKELMRQRQQQQEALRRLQQQQQQQQLA 919
Score = 39.7 bits (91), Expect = 0.003
Identities = 46/218 (21%), Positives = 92/218 (42%), Gaps = 45/218 (20%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDF----DDIQ 58
++E+ ++ EEE + QEEA EE EE+ R + + E E + ++ Q
Sbjct: 799 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 858
Query: 59 KK-RQNKDLMELQALIDSHFEA-RKKEEEELVALKERIEKRRAERAEQQRIRAEK----- 111
++ +N+ ME +A H E RK++E E+ KE + +R+ ++ +R++ ++
Sbjct: 859 RRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQL 918
Query: 112 ----------------------------------ERERQNRLAEEKARREEEDAKRRAED 137
E ER+ +L EE+ R++ E K +
Sbjct: 919 AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ 978
Query: 138 DLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 175
++++ LS G +++ AR+M+K+
Sbjct: 979 QQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
Score = 30.8 bits (68), Expect = 1.2
Identities = 27/126 (21%), Positives = 49/126 (38%), Gaps = 16/126 (12%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
EE E +E EE + +EE EP++ + EGEK D ++ +
Sbjct: 319 EEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNK--------KEGEKTDRVGVEASEET 370
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEK 123
A + + + +E + +R+ E +Q +AE+E +N L +
Sbjct: 371 PQTSSSSARPGTPSDHQSQEASQF--------ERKDEPKTEQTEKAEEETRMENSLPAKV 422
Query: 124 ARREEE 129
R +E
Sbjct: 423 PSRGDE 428
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 58.2 bits (139), Expect = 7e-09
Identities = 61/266 (22%), Positives = 120/266 (45%), Gaps = 20/266 (7%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPR--PKLTAPKIPEGEKVDFDD--- 56
++ ++ EE+ + +EE + + E+ E E K R +L K E + +
Sbjct: 744 AEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIA 803
Query: 57 IQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQ 116
++++R+ ++ + + + E R++EEEE +E + K+ E A+ A +E E Q
Sbjct: 804 LRRQREEEERQQQEEAL-RRLEERRREEEERRKQEELLRKQEEEAAKW----AREEEEAQ 858
Query: 117 NRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 176
RL E + R EEE A+ R E++ +K+K L + + Q+ ++ ++ +++
Sbjct: 859 RRLEENRLRMEEEAARLRHEEEERKRKEL-EVQRQKELMRQRQQQQEALRRLQQQQQQQQ 917
Query: 177 LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFE------FGEKLKRQKYDITTLR 230
LA+ + P + + A + TL EI K E E+ +RQ+ ++
Sbjct: 918 LAQMKLPSS--STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 975
Query: 231 SRIDQAQKHSKKAGTPAKGKVGGRWK 256
+ Q Q+ K +G K G K
Sbjct: 976 QQ-QQQQQQQKLSGWGNVSKPSGTTK 1000
Score = 53.5 bits (127), Expect = 2e-07
Identities = 39/184 (21%), Positives = 96/184 (52%), Gaps = 11/184 (5%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
E+++Q+E+ + E + AE+ + E E K + +L + E + ++ +K+R+
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ-EEILRRQQEEERKRREE 782
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER--ERQNRLAE 121
++L + EA +++ E+ +AL+ + E+ ++ E+ R E+ R E + R E
Sbjct: 783 EELARRK-----QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 837
Query: 122 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAK---ADQKRGKKQTAREMKKKILA 178
E R++EE+A + A ++ + ++ L A+ +++R +K+ + +K+++
Sbjct: 838 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897
Query: 179 ERRK 182
+R++
Sbjct: 898 QRQQ 901
Score = 52.8 bits (125), Expect = 3e-07
Identities = 49/195 (25%), Positives = 91/195 (46%), Gaps = 18/195 (9%)
Query: 38 RPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKR 97
+P + P + EG V + L +LQ L + +A K E+E R +
Sbjct: 695 QPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKA--KAAKLEQER------REAEM 746
Query: 98 RAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLA 157
RA+R E++R R E+ R +Q + R++EE+ KRR E++L ++K ++ +A
Sbjct: 747 RAKREEEERKRQEELRRQQEEILR---RQQEEERKRREEEELARRKQEEALRRQREQEIA 803
Query: 158 KADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDK-------AKELWETLHQLEI 210
Q+ +++ +E + L ERR+ E+ LR + A+E E +LE
Sbjct: 804 LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE 863
Query: 211 DKFEFGEKLKRQKYD 225
++ E+ R +++
Sbjct: 864 NRLRMEEEAARLRHE 878
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/208 (22%), Positives = 98/208 (47%), Gaps = 17/208 (8%)
Query: 44 PKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKE----EEELVALKERIEKRRA 99
P + + ++++ K Q + E++A + R++E +EE++ ++ E++R
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
Query: 100 ERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDD----LKKKKALSSMGANYSSY 155
E E R R ++E R+ R E RR+ E+ +R+ +++ L++++
Sbjct: 781 EEEELAR-RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839
Query: 156 LAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEF 215
L K +++ K ARE ++ A+RR N + E+ R + +E +LE+ +
Sbjct: 840 LRKQEEEAAK--WAREEEE---AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR--- 891
Query: 216 GEKLKRQKYDITTLRSRIDQAQKHSKKA 243
++L RQ+ R+ Q Q+ + A
Sbjct: 892 QKELMRQRQQQQEALRRLQQQQQQQQLA 919
Score = 39.7 bits (91), Expect = 0.003
Identities = 46/218 (21%), Positives = 92/218 (42%), Gaps = 45/218 (20%)
Query: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDF----DDIQ 58
++E+ ++ EEE + QEEA EE EE+ R + + E E + ++ Q
Sbjct: 799 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 858
Query: 59 KK-RQNKDLMELQALIDSHFEA-RKKEEEELVALKERIEKRRAERAEQQRIRAEK----- 111
++ +N+ ME +A H E RK++E E+ KE + +R+ ++ +R++ ++
Sbjct: 859 RRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQL 918
Query: 112 ----------------------------------ERERQNRLAEEKARREEEDAKRRAED 137
E ER+ +L EE+ R++ E K +
Sbjct: 919 AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ 978
Query: 138 DLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 175
++++ LS G +++ AR+M+K+
Sbjct: 979 QQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
Score = 30.8 bits (68), Expect = 1.2
Identities = 27/126 (21%), Positives = 49/126 (38%), Gaps = 16/126 (12%)
Query: 4 EEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 63
EE E +E EE + +EE EP++ + EGEK D ++ +
Sbjct: 319 EEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNK--------KEGEKTDRVGVEASEET 370
Query: 64 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEK 123
A + + + +E + +R+ E +Q +AE+E +N L +
Sbjct: 371 PQTSSSSARPGTPSDHQSQEASQF--------ERKDEPKTEQTEKAEEETRMENSLPAKV 422
Query: 124 ARREEE 129
R +E
Sbjct: 423 PSRGDE 428
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 58.2 bits (139), Expect = 7e-09
Identities = 55/251 (21%), Positives = 119/251 (47%), Gaps = 24/251 (9%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK 60
+ +++ ++EE + EE + + E V + +E+ + ++ EK + ++
Sbjct: 559 VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERL 618
Query: 61 RQNKDLMELQALIDSHFEARKKEEEE---LVALKERIEKRRAERAEQQRIRAEKERERQN 117
+ K + A EAR+K+EEE L L++ E+RR + Q+ + E+E+ER
Sbjct: 619 AEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK--KKEEEQERLR 676
Query: 118 RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL 177
+ AE K E+ + +RR ++ +++ + +Q+R ++Q RE ++++
Sbjct: 677 KAAEAKRLAEQREQERREQERREQE---------------RREQER-REQERREQERQLA 720
Query: 178 AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 237
+ R+ E +L+++ K L QL+ E EK K+++ R ++ +
Sbjct: 721 EQERRREQERLQAERELQEREKALRLQKEQLQ---RELEEKKKKEEQQRLAERQLQEEQE 777
Query: 238 KHSKKAGTPAK 248
K +K+A +K
Sbjct: 778 KKAKEAAGASK 788
Score = 42.4 bits (98), Expect = 4e-04
Identities = 45/143 (31%), Positives = 71/143 (49%), Gaps = 16/143 (11%)
Query: 91 KERIEK-RRAERAEQQRIRAEKERERQNRLAEEKARREEE-----DAKRRAED-DLKKKK 143
++R+E RR E AEQ R R + E +++ RL E K +REE A+ R E +KKK
Sbjct: 539 RQRLENLRRKEEAEQLR-RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKK 597
Query: 144 ALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGED---KLRDKAKE 200
+ A KA ++R ++ A KKK A++ + + E+ +LR +E
Sbjct: 598 QIEQKFAQIDEKTEKAKEERLAEEKA---KKKAAAKKMEEVEARRKQEEEARRLRWLQQE 654
Query: 201 LWETLHQ--LEIDKFEFGEKLKR 221
E HQ L+ K E E+L++
Sbjct: 655 EEERRHQELLQKKKEEEQERLRK 677
Score = 37.4 bits (85), Expect = 0.013
Identities = 52/229 (22%), Positives = 98/229 (42%), Gaps = 29/229 (12%)
Query: 20 QEEAAEVHEEVH-EPEEKPRPKLTAPKIP-EGEKVDFDDIQKKRQNKDLMELQALIDSHF 77
++ +E+ EE H E EE P+ P P KV ++ R ++ ++ +
Sbjct: 454 KQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV----VRPLRTFLHTVQRNQMLMTPT 509
Query: 78 EARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAED 137
A + +K I++ R + + EKER+R L R+EE + RR +
Sbjct: 510 SAPRS------VMKSFIKRNTPLRMDPKCSFVEKERQRLENLR----RKEEAEQLRRQKV 559
Query: 138 DLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDK 197
+ K++ L + L K Q R + + +E KKK + ++ + D+ +K
Sbjct: 560 EEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQI-------DEKTEK 612
Query: 198 AKELWETLHQLEIDKFEFGEKLK----RQKYDITTLRSRIDQAQKHSKK 242
AKE E L + + K +K++ R+K + R R Q ++ ++
Sbjct: 613 AKE--ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 659
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 58.2 bits (139), Expect = 7e-09
Identities = 55/251 (21%), Positives = 119/251 (47%), Gaps = 24/251 (9%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEKPRPKLTAPKIPEGEKVDFDDIQKK 60
+ +++ ++EE + EE + + E V + +E+ + ++ EK + ++
Sbjct: 555 VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERL 614
Query: 61 RQNKDLMELQALIDSHFEARKKEEEE---LVALKERIEKRRAERAEQQRIRAEKERERQN 117
+ K + A EAR+K+EEE L L++ E+RR + Q+ + E+E+ER
Sbjct: 615 AEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK--KKEEEQERLR 672
Query: 118 RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL 177
+ AE K E+ + +RR ++ +++ + +Q+R ++Q RE ++++
Sbjct: 673 KAAEAKRLAEQREQERREQERREQE---------------RREQER-REQERREQERQLA 716
Query: 178 AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 237
+ R+ E +L+++ K L QL+ E EK K+++ R ++ +
Sbjct: 717 EQERRREQERLQAERELQEREKALRLQKEQLQ---RELEEKKKKEEQQRLAERQLQEEQE 773
Query: 238 KHSKKAGTPAK 248
K +K+A +K
Sbjct: 774 KKAKEAAGASK 784
Score = 43.5 bits (101), Expect = 2e-04
Identities = 61/224 (27%), Positives = 95/224 (42%), Gaps = 29/224 (12%)
Query: 18 EAQEEAAEVHEEVHEPEEK-PRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSH 76
E EE EE+ P K P A K+ + +Q+ + +
Sbjct: 459 ELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKS 518
Query: 77 FEARK-------KEEEELVALKERIEK-RRAERAEQQRIRAEKERERQNRLAEEKARREE 128
F R KE+E ++R+E RR E AEQ R R + E +++ RL E K +REE
Sbjct: 519 FIKRNTPLRMDPKEKE-----RQRLENLRRKEEAEQLR-RQKVEEDKRRRLEEVKLKREE 572
Query: 129 E-----DAKRRAED-DLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 182
A+ R E +KKK + A KA ++R ++ A KKK A++ +
Sbjct: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKA---KKKAAAKKME 629
Query: 183 PLNIDHLGED---KLRDKAKELWETLHQ--LEIDKFEFGEKLKR 221
+ E+ +LR +E E HQ L+ K E E+L++
Sbjct: 630 EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK 673
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.126 0.331
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,114,101
Number of Sequences: 37866
Number of extensions: 538354
Number of successful extensions: 24055
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 758
Number of HSP's successfully gapped in prelim test: 1003
Number of HSP's that attempted gapping in prelim test: 6014
Number of HSP's gapped (non-prelim): 7730
length of query: 256
length of database: 18,247,518
effective HSP length: 100
effective length of query: 156
effective length of database: 14,460,918
effective search space: 2255903208
effective search space used: 2255903208
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.