Search of human proteins with 10190670

Search of human proteins with 10190670

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10190670 growth differentiation factor 3 precursor [Homo
sapiens]
         (364 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10190670 growth differentiation factor 3 precursor [Homo sapi...   755   0.0  
gi|110349792 growth differentiation factor 1 [Homo sapiens]           192   3e-49
gi|4557369 bone morphogenetic protein 2 preproprotein [Homo sapi...   155   5e-38
gi|157276597 bone morphogenetic protein 4 preproprotein [Homo sa...   150   1e-36
gi|157276595 bone morphogenetic protein 4 preproprotein [Homo sa...   150   1e-36
gi|157276593 bone morphogenetic protein 4 preproprotein [Homo sa...   150   1e-36
gi|4502425 bone morphogenetic protein 6 preproprotein [Homo sapi...   140   1e-33
gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]      128   9e-30
gi|10835091 bone morphogenetic protein 5 preproprotein [Homo sap...   126   3e-29
gi|29571106 bone morphogenetic protein 8B preproprotein [Homo sa...   125   6e-29
gi|145611428 bone morphogenetic protein 8A [Homo sapiens]             125   6e-29
gi|4503969 growth differentiation factor 5 preproprotein [Homo s...   119   6e-27
gi|48475062 growth differentiation factor 6 precursor [Homo sapi...   112   5e-25
gi|4504699 inhibin beta A precursor [Homo sapiens]                    109   4e-24
gi|61835232 growth differentiation factor 7 preproprotein [Homo ...   105   6e-23
gi|126507087 bone morphogenetic protein 3 preproprotein [Homo sa...   103   2e-22
gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]      100   3e-21
gi|4826740 growth differentiation factor 10 precursor [Homo sapi...    99   6e-21
gi|7705308 growth differentiation factor 2 [Homo sapiens]              96   5e-20
gi|7656928 bone morphogenetic protein 10 preproprotein [Homo sap...    95   9e-20
gi|222352098 nodal precursor [Homo sapiens]                            95   1e-19
gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens]      92   9e-19
gi|13899338 activin beta E [Homo sapiens]                              89   8e-18
gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]           86   5e-17
gi|4885259 myostatin [Homo sapiens]                                    85   9e-17
gi|5031613 growth differentiation factor 11 precursor [Homo sapi...    79   8e-15
gi|4885261 growth differentiation factor 9 precursor [Homo sapiens]    78   1e-14
gi|4507465 transforming growth factor, beta 3 [Homo sapiens]           71   2e-12
gi|63025222 transforming growth factor, beta 1 [Homo sapiens]          63   4e-10
gi|153792495 growth differentiation factor 15 [Homo sapiens]           63   5e-10

>gi|10190670 growth differentiation factor 3 precursor [Homo
           sapiens]
          Length = 364

 Score =  755 bits (1949), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 1   MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIFQDREA 60
           MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIFQDREA
Sbjct: 1   MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIFQDREA 60

Query: 61  AATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAIKERE 120
           AATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAIKERE
Sbjct: 61  AATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAIKERE 120

Query: 121 QLTLAQLGLDLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFVLRSVPWPQGAVH 180
           QLTLAQLGLDLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFVLRSVPWPQGAVH
Sbjct: 121 QLTLAQLGLDLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFVLRSVPWPQGAVH 180

Query: 181 FNLLDVAKDWNDNPRKNFGLFLEILVKEDRDSGVNFQPEDTCARLRCSLHASLLVVTLNP 240
           FNLLDVAKDWNDNPRKNFGLFLEILVKEDRDSGVNFQPEDTCARLRCSLHASLLVVTLNP
Sbjct: 181 FNLLDVAKDWNDNPRKNFGLFLEILVKEDRDSGVNFQPEDTCARLRCSLHASLLVVTLNP 240

Query: 241 DQCHPSRKRRAAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFS 300
           DQCHPSRKRRAAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFS
Sbjct: 241 DQCHPSRKRRAAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFS 300

Query: 301 LTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDE 360
           LTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDE
Sbjct: 301 LTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDE 360

Query: 361 CGCG 364
           CGCG
Sbjct: 361 CGCG 364


>gi|110349792 growth differentiation factor 1 [Homo sapiens]
          Length = 372

 Score =  192 bits (489), Expect = 3e-49
 Identities = 133/357 (37%), Positives = 198/357 (55%), Gaps = 48/357 (13%)

Query: 30  LQFLGL-DKAPSPQKFQPVPYILKKIFQDREAAATT--------GVSRDLCYVKELGVRG 80
           LQ LGL D+     + +PVP ++ ++F+ R+   T         GV+   C+V+ELGV G
Sbjct: 40  LQALGLRDEPQGAPRLRPVPPVMWRLFRRRDPQETRSGSRRTSPGVTLQPCHVEELGVAG 99

Query: 81  NVLRFLPDQGFFLYPKKISQASS----CLQKLLYFNLSAIKEREQLTLAQLGLDLGPNSY 136
           N++R +PD+G    P + S+ +S    C +  + F+LSA++  E+ + A+L L     + 
Sbjct: 100 NIVRHIPDRGA---PTRASEPASAAGHCPEWTVVFDLSAVEPAERPSRARLELRFAAAAA 156

Query: 137 YNLGPELELALFLVQEPHVWGQTTPKPGKMFVLRSVPWPQGAVHFNLLDVAKDWNDNPRK 196
               PE    L + Q     G     PG + + + VP     V   LL  A  W  N   
Sbjct: 157 --AAPEGGWELSVAQAGQGAGAD---PGPVLLRQLVPALGPPVRAELLGAA--WARNASW 209

Query: 197 NFGLFLEILVKEDRDSGVNFQPEDTCARLRCSLHASLLVVTLNPDQCHP-SRKRRAAIPV 255
              L L + ++    +         CARL     ASLL+VTL+P  CHP +R RR A PV
Sbjct: 210 PRSLRLALALRPRAPAA--------CARLA---EASLLLVTLDPRLCHPLARPRRDAEPV 258

Query: 256 PKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSS------N 309
                   C   +L+++FR++GWH+W+IAP+GF+ANYC G+C  +L ++L+ S      N
Sbjct: 259 LGGGPGGACRARRLYVSFREVGWHRWVIAPRGFLANYCQGQC--ALPVALSGSGGPPALN 316

Query: 310 YAFMQALMHAVDP---EIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
           +A ++ALMHA  P   ++P   C+P +LSPIS+L+ DN+DNV+LR YEDMVVDECGC
Sbjct: 317 HAVLRALMHAAAPGAADLP--CCVPARLSPISVLFFDNSDNVVLRQYEDMVVDECGC 371


>gi|4557369 bone morphogenetic protein 2 preproprotein [Homo
           sapiens]
          Length = 396

 Score =  155 bits (392), Expect = 5e-38
 Identities = 112/359 (31%), Positives = 178/359 (49%), Gaps = 38/359 (10%)

Query: 26  EYVFLQFLGLDKAPSPQKFQPVPYILKKIFQDREAAATTGVSRDLCYVKELGVRGNVLRF 85
           E   L   GL + P+P +   VP  +  ++  R  +   G       ++    R N +R 
Sbjct: 54  ELRLLSMFGLKQRPTPSRDAVVPPYMLDLY--RRHSGQPGSPAPDHRLERAASRANTVRS 111

Query: 86  LPDQGFFLYPKKISQASSCLQKLLYFNLSAIKEREQLTLAQLGL-------DLGPNSYYN 138
              +      +++ + S    +  +FNLS+I   E +T A+L +        LG NS ++
Sbjct: 112 FHHEESL---EELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFH 168

Query: 139 LGPELELALFLVQEPHVWGQTTPKPGKMFVLRSVPWPQGAVHFNLLDVAKD---WNDNPR 195
                 + ++ + +P       P   ++   R V   Q A  +   DV      W     
Sbjct: 169 H----RINIYEIIKPATANSKFPVT-RLLDTRLVN--QNASRWESFDVTPAVMRWTAQGH 221

Query: 196 KNFGLFLEILVKEDRDSGVNFQPEDTCARLRCSLHAS---------LLVVTLNPDQCHPS 246
            N G  +E+   E++  GV+ +      R+  SLH           LLV   +  + HP 
Sbjct: 222 ANHGFVVEVAHLEEKQ-GVSKRH----VRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPL 276

Query: 247 RKR--RAAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTIS 304
            KR  R A    +   K+ C RH L+++F D+GW+ WI+AP G+ A YCHGECPF L   
Sbjct: 277 HKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADH 336

Query: 305 LNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
           LNS+N+A +Q L+++V+ +IP+A C+PT+LS ISMLY D N+ V+L++Y+DMVV+ CGC
Sbjct: 337 LNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGC 395


>gi|157276597 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score =  150 bits (380), Expect = 1e-36
 Identities = 111/369 (30%), Positives = 175/369 (47%), Gaps = 50/369 (13%)

Query: 26  EYVFLQFLGLDKAPSPQKFQPVPYILKKIF------QDREAAATTGVSRDLCYVKELGVR 79
           E   LQ  GL + P P K   +P  ++ ++      ++ E   +TG+     Y +    R
Sbjct: 58  EATLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLE----YPERPASR 113

Query: 80  GNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAIKEREQLTLAQLGLDLGPNSYYNL 139
            N +R    +      + I   S        FNLS+I E E ++ A+L L        + 
Sbjct: 114 ANTVRSFHHEEHL---ENIPGTSENSAFRFLFNLSSIPENEVISSAELRLF---REQVDQ 167

Query: 140 GPELE-----LALFLVQEPHVWGQTTPKPGKMF--VLRSVPWPQGAVHFNLLDVAKD--- 189
           GP+ E     + ++ V +P         PG +   +L +         +   DV+     
Sbjct: 168 GPDWERGFHRINIYEVMKP----PAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLR 223

Query: 190 WNDNPRKNFGLFLEIL----VKEDRDSGVNF-----QPEDTCARLRCSLHASLLVVTLNP 240
           W    + N+GL +E+      +  +   V       Q     A+LR      LLV   + 
Sbjct: 224 WTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLR-----PLLVTFGHD 278

Query: 241 DQCHPSRKRRAAIPVPKLSCKNL------CHRHQLFINFRDLGWHKWIIAPKGFMANYCH 294
            + H   +RR A   PK   +        C RH L+++F D+GW+ WI+AP G+ A YCH
Sbjct: 279 GRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCH 338

Query: 295 GECPFSLTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYE 354
           G+CPF L   LNS+N+A +Q L+++V+  IP+A C+PT+LS ISMLY D  D V+L++Y+
Sbjct: 339 GDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQ 398

Query: 355 DMVVDECGC 363
           +MVV+ CGC
Sbjct: 399 EMVVEGCGC 407


>gi|157276595 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score =  150 bits (380), Expect = 1e-36
 Identities = 111/369 (30%), Positives = 175/369 (47%), Gaps = 50/369 (13%)

Query: 26  EYVFLQFLGLDKAPSPQKFQPVPYILKKIF------QDREAAATTGVSRDLCYVKELGVR 79
           E   LQ  GL + P P K   +P  ++ ++      ++ E   +TG+     Y +    R
Sbjct: 58  EATLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLE----YPERPASR 113

Query: 80  GNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAIKEREQLTLAQLGLDLGPNSYYNL 139
            N +R    +      + I   S        FNLS+I E E ++ A+L L        + 
Sbjct: 114 ANTVRSFHHEEHL---ENIPGTSENSAFRFLFNLSSIPENEVISSAELRLF---REQVDQ 167

Query: 140 GPELE-----LALFLVQEPHVWGQTTPKPGKMF--VLRSVPWPQGAVHFNLLDVAKD--- 189
           GP+ E     + ++ V +P         PG +   +L +         +   DV+     
Sbjct: 168 GPDWERGFHRINIYEVMKP----PAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLR 223

Query: 190 WNDNPRKNFGLFLEIL----VKEDRDSGVNF-----QPEDTCARLRCSLHASLLVVTLNP 240
           W    + N+GL +E+      +  +   V       Q     A+LR      LLV   + 
Sbjct: 224 WTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLR-----PLLVTFGHD 278

Query: 241 DQCHPSRKRRAAIPVPKLSCKNL------CHRHQLFINFRDLGWHKWIIAPKGFMANYCH 294
            + H   +RR A   PK   +        C RH L+++F D+GW+ WI+AP G+ A YCH
Sbjct: 279 GRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCH 338

Query: 295 GECPFSLTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYE 354
           G+CPF L   LNS+N+A +Q L+++V+  IP+A C+PT+LS ISMLY D  D V+L++Y+
Sbjct: 339 GDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQ 398

Query: 355 DMVVDECGC 363
           +MVV+ CGC
Sbjct: 399 EMVVEGCGC 407


>gi|157276593 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score =  150 bits (380), Expect = 1e-36
 Identities = 111/369 (30%), Positives = 175/369 (47%), Gaps = 50/369 (13%)

Query: 26  EYVFLQFLGLDKAPSPQKFQPVPYILKKIF------QDREAAATTGVSRDLCYVKELGVR 79
           E   LQ  GL + P P K   +P  ++ ++      ++ E   +TG+     Y +    R
Sbjct: 58  EATLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLE----YPERPASR 113

Query: 80  GNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAIKEREQLTLAQLGLDLGPNSYYNL 139
            N +R    +      + I   S        FNLS+I E E ++ A+L L        + 
Sbjct: 114 ANTVRSFHHEEHL---ENIPGTSENSAFRFLFNLSSIPENEVISSAELRLF---REQVDQ 167

Query: 140 GPELE-----LALFLVQEPHVWGQTTPKPGKMF--VLRSVPWPQGAVHFNLLDVAKD--- 189
           GP+ E     + ++ V +P         PG +   +L +         +   DV+     
Sbjct: 168 GPDWERGFHRINIYEVMKP----PAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLR 223

Query: 190 WNDNPRKNFGLFLEIL----VKEDRDSGVNF-----QPEDTCARLRCSLHASLLVVTLNP 240
           W    + N+GL +E+      +  +   V       Q     A+LR      LLV   + 
Sbjct: 224 WTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLR-----PLLVTFGHD 278

Query: 241 DQCHPSRKRRAAIPVPKLSCKNL------CHRHQLFINFRDLGWHKWIIAPKGFMANYCH 294
            + H   +RR A   PK   +        C RH L+++F D+GW+ WI+AP G+ A YCH
Sbjct: 279 GRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCH 338

Query: 295 GECPFSLTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYE 354
           G+CPF L   LNS+N+A +Q L+++V+  IP+A C+PT+LS ISMLY D  D V+L++Y+
Sbjct: 339 GDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQ 398

Query: 355 DMVVDECGC 363
           +MVV+ CGC
Sbjct: 399 EMVVEGCGC 407


>gi|4502425 bone morphogenetic protein 6 preproprotein [Homo
           sapiens]
          Length = 513

 Score =  140 bits (354), Expect = 1e-33
 Identities = 90/280 (32%), Positives = 140/280 (50%), Gaps = 34/280 (12%)

Query: 111 FNLSAIKEREQLTLAQLGL--DLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFV 168
           FNLS I E E +T A+  +  D    S+ N         FL+    V  +   +   +F+
Sbjct: 240 FNLSQIPEGEVVTAAEFRIYKDCVMGSFKN-------QTFLISIYQVLQEHQHRDSDLFL 292

Query: 169 LRS-VPWP--QGAVHFNLLDVAKDWNDNPRKNFGLFLEILVKED------------RDSG 213
           L + V W   +G + F++   +  W   P+ N GL L ++ ++             RD  
Sbjct: 293 LDTRVVWASEEGWLEFDITATSNLWVVTPQHNMGLQLSVVTRDGVHVHPRAAGLVGRDGP 352

Query: 214 VNFQPEDTCARLRCSLHASLLVVTLNPDQCHPSRKRRAAIPVPKLSC---------KNLC 264
            + QP          +H        +  +     +   +  V ++S          K  C
Sbjct: 353 YDKQPFMVAFFKVSEVHVRTTRSASSRRRQQSRNRSTQSQDVARVSSASDYNSSELKTAC 412

Query: 265 HRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPE- 323
            +H+L+++F+DLGW  WIIAPKG+ ANYC GEC F L   +N++N+A +Q L+H ++PE 
Sbjct: 413 RKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPEY 472

Query: 324 IPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
           +P+  C PTKL+ IS+LY D+N NVIL+ Y +MVV  CGC
Sbjct: 473 VPKPCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGC 512


>gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]
          Length = 431

 Score =  128 bits (321), Expect = 9e-30
 Identities = 86/280 (30%), Positives = 143/280 (51%), Gaps = 34/280 (12%)

Query: 111 FNLSAIKEREQLTLAQLGL--DLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFV 168
           F+LS I E E +T A+  +  D     + N      ++++ V + H+  ++      +F+
Sbjct: 158 FDLSKIPEGEAVTAAEFRIYKDYIRERFDN--ETFRISVYQVLQEHLGRESD-----LFL 210

Query: 169 LRS-VPWP--QGAVHFNLLDVAKDWNDNPRKNFGLFLEILVKED------------RDSG 213
           L S   W   +G + F++   +  W  NPR N GL L +   +             R   
Sbjct: 211 LDSRTLWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLDGQSINPKLAGLIGRHGP 270

Query: 214 VNFQPEDTCARLRCSLHASLLVVTLNPDQCH---PSRKRRAAIPVPKLS------CKNLC 264
            N QP          +H   +  T +  +      + K + A+ +  ++       +  C
Sbjct: 271 QNKQPFMVAFFKATEVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQAC 330

Query: 265 HRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPE- 323
            +H+L+++FRDLGW  WIIAP+G+ A YC GEC F L   +N++N+A +Q L+H ++PE 
Sbjct: 331 KKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPET 390

Query: 324 IPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
           +P+  C PT+L+ IS+LY D++ NVIL+ Y +MVV  CGC
Sbjct: 391 VPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGC 430


>gi|10835091 bone morphogenetic protein 5 preproprotein [Homo
           sapiens]
          Length = 454

 Score =  126 bits (316), Expect = 3e-29
 Identities = 83/279 (29%), Positives = 140/279 (50%), Gaps = 33/279 (11%)

Query: 111 FNLSAIKEREQLTLAQLGL--DLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFV 168
           F+L+ I   E +T A+  +  D   N + N    ++++++ + + +     T +   +F+
Sbjct: 182 FDLTQIPHGEAVTAAEFRIYKDRSNNRFEN--ETIKISIYQIIKEY-----TNRDADLFL 234

Query: 169 L---RSVPWPQGAVHFNLLDVAKDWNDNPRKNFGLFLEILVKEDRDSGVNFQ-------P 218
           L   ++     G + F++   +  W  NP+ N GL L     + R   V          P
Sbjct: 235 LDTRKAQALDVGWLVFDITVTSNHWVINPQNNLGLQLCAETGDGRSINVKSAGLVGRQGP 294

Query: 219 EDTCARLRCSLHASLLVV------------TLNPDQCHPSRKRRAAIPVPKLS-CKNLCH 265
           +     +     AS +++              N    H    R +++     S  K  C 
Sbjct: 295 QSKQPFMVAFFKASEVLLRSVRAANKRKNQNRNKSSSHQDSSRMSSVGDYNTSEQKQACK 354

Query: 266 RHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPE-I 324
           +H+L+++FRDLGW  WIIAP+G+ A YC GEC F L   +N++N+A +Q L+H + P+ +
Sbjct: 355 KHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHV 414

Query: 325 PQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
           P+  C PTKL+ IS+LY D++ NVIL+ Y +MVV  CGC
Sbjct: 415 PKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGC 453


>gi|29571106 bone morphogenetic protein 8B preproprotein [Homo
           sapiens]
          Length = 402

 Score =  125 bits (314), Expect = 6e-29
 Identities = 52/104 (50%), Positives = 79/104 (75%), Gaps = 1/104 (0%)

Query: 261 KNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAV 320
           + +C RH+L+++F+DLGW  W+IAP+G+ A YC GEC F L   +N++N+A +Q+L+H +
Sbjct: 298 RQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLM 357

Query: 321 DPE-IPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
            P+ +P+A C PTKLS  S+LY D+++NVILR + +MVV  CGC
Sbjct: 358 MPDAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401


>gi|145611428 bone morphogenetic protein 8A [Homo sapiens]
          Length = 402

 Score =  125 bits (314), Expect = 6e-29
 Identities = 52/104 (50%), Positives = 78/104 (75%), Gaps = 1/104 (0%)

Query: 261 KNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAV 320
           + +C RH+L+++F+DLGW  W+IAP+G+ A YC GEC F L   +N++N+A +Q+L+H +
Sbjct: 298 RQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLM 357

Query: 321 DPE-IPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
            P  +P+A C PTKLS  S+LY D+++NVILR + +MVV  CGC
Sbjct: 358 KPNAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401


>gi|4503969 growth differentiation factor 5 preproprotein [Homo
           sapiens]
          Length = 501

 Score =  119 bits (297), Expect = 6e-27
 Identities = 57/123 (46%), Positives = 79/123 (64%), Gaps = 6/123 (4%)

Query: 247 RKRRAAIPV-----PKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSL 301
           RKRRA +       P  + K  C R  L +NF+D+GW  WIIAP  + A +C G C F L
Sbjct: 378 RKRRAPLATRQGKRPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPL 437

Query: 302 TISLNSSNYAFMQALMHAVDPE-IPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDE 360
              L  +N+A +Q LM+++DPE  P   C+PT+LSPIS+L+ D+ +NV+ + YEDMVV+ 
Sbjct: 438 RSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVES 497

Query: 361 CGC 363
           CGC
Sbjct: 498 CGC 500


>gi|48475062 growth differentiation factor 6 precursor [Homo
           sapiens]
          Length = 455

 Score =  112 bits (280), Expect = 5e-25
 Identities = 49/101 (48%), Positives = 69/101 (68%), Gaps = 1/101 (0%)

Query: 264 CHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDP- 322
           C +  L +NF++LGW  WIIAP  + A +C G C F L   L  +N+A +Q LM+++DP 
Sbjct: 354 CSKKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRSHLEPTNHAIIQTLMNSMDPG 413

Query: 323 EIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
             P + C+PTKL+PIS+LY D  +NV+ + YEDMVV+ CGC
Sbjct: 414 STPPSCCVPTKLTPISILYIDAGNNVVYKQYEDMVVESCGC 454


>gi|4504699 inhibin beta A precursor [Homo sapiens]
          Length = 426

 Score =  109 bits (272), Expect = 4e-24
 Identities = 53/143 (37%), Positives = 84/143 (58%), Gaps = 15/143 (10%)

Query: 230 HASLLVVTLNPDQCHPSRKRRAAIPVPKLSCK---NLCHRHQLFINFRDLGWHKWIIAPK 286
           H   L++     + HP R+RR       L C    N+C + Q F++F+D+GW+ WIIAP 
Sbjct: 289 HRPFLMLQARQSEDHPHRRRRRG-----LECDGKVNICCKKQFFVSFKDIGWNDWIIAPS 343

Query: 287 GFMANYCHGECPFSL------TISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISML 340
           G+ ANYC GECP  +      ++S +S+     +   H+    + ++ C+PTKL P+SML
Sbjct: 344 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANL-KSCCVPTKLRPMSML 402

Query: 341 YQDNNDNVILRHYEDMVVDECGC 363
           Y D+  N+I +  ++M+V+ECGC
Sbjct: 403 YYDDGQNIIKKDIQNMIVEECGC 425


>gi|61835232 growth differentiation factor 7 preproprotein [Homo
           sapiens]
          Length = 450

 Score =  105 bits (262), Expect = 6e-23
 Identities = 46/104 (44%), Positives = 70/104 (67%), Gaps = 1/104 (0%)

Query: 261 KNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAV 320
           ++ C R  L ++F++LGW  WIIAP  + A +C G C F L   L  +N+A +Q L++++
Sbjct: 346 RSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSM 405

Query: 321 DPE-IPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
            P+  P + C+P +LSPIS+LY D  +NV+ + YEDMVV+ CGC
Sbjct: 406 APDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449


>gi|126507087 bone morphogenetic protein 3 preproprotein [Homo
           sapiens]
          Length = 472

 Score =  103 bits (257), Expect = 2e-22
 Identities = 46/102 (45%), Positives = 67/102 (65%), Gaps = 2/102 (1%)

Query: 264 CHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVD-- 321
           C R  L ++F D+GW +WII+PK F A YC G C F +  SL  SN+A +Q+++ AV   
Sbjct: 370 CARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGVV 429

Query: 322 PEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
           P IP+  C+P K+S +S+L+ D N NV+L+ Y +M V+ C C
Sbjct: 430 PGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVESCAC 471


>gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]
          Length = 407

 Score =  100 bits (248), Expect = 3e-21
 Identities = 48/106 (45%), Positives = 67/106 (63%), Gaps = 4/106 (3%)

Query: 262 NLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLT-ISLNSSNY---AFMQALM 317
           NLC R Q FI+FR +GW+ WIIAP G+  NYC G CP  L  +  ++S++      Q  M
Sbjct: 301 NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM 360

Query: 318 HAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
             ++P    + CIPTKLS +SMLY D+  N++ R   +M+V+ECGC
Sbjct: 361 RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406


>gi|4826740 growth differentiation factor 10 precursor [Homo
           sapiens]
          Length = 478

 Score = 99.0 bits (245), Expect = 6e-21
 Identities = 43/103 (41%), Positives = 67/103 (65%), Gaps = 2/103 (1%)

Query: 263 LCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVD- 321
           +C R  L ++F D+GW++WII+PK F A YC G C F +   +  SN+A +Q+++ AV  
Sbjct: 375 VCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGI 434

Query: 322 -PEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
            P IP+  C+P K++ + +L+ D N NV+L+ Y +M VD C C
Sbjct: 435 IPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCAC 477


>gi|7705308 growth differentiation factor 2 [Homo sapiens]
          Length = 429

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 47/102 (46%), Positives = 64/102 (62%), Gaps = 2/102 (1%)

Query: 264 CHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDP- 322
           C +  L +NF D+GW  WIIAPK + A  C G C F L   +  + +A +Q L+H   P 
Sbjct: 327 CQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPT 386

Query: 323 EIPQAVCIPTKLSPISMLYQDNNDNVILR-HYEDMVVDECGC 363
           ++ +A C+PTKLSPIS+LY+D+     L+ HYE M V ECGC
Sbjct: 387 KVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGC 428


>gi|7656928 bone morphogenetic protein 10 preproprotein [Homo
           sapiens]
          Length = 424

 Score = 95.1 bits (235), Expect = 9e-20
 Identities = 45/103 (43%), Positives = 61/103 (59%), Gaps = 1/103 (0%)

Query: 262 NLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVD 321
           N C R  L+I+F+++GW  WIIAP G+ A  C G C + L   L  + +A +QAL+H  +
Sbjct: 321 NYCKRTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPLAEHLTPTKHAIIQALVHLKN 380

Query: 322 PE-IPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
            +   +A C+PTKL PIS+LY D         YE M V ECGC
Sbjct: 381 SQKASKACCVPTKLEPISILYLDKGVVTYKFKYEGMAVSECGC 423


>gi|222352098 nodal precursor [Homo sapiens]
          Length = 347

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 46/118 (38%), Positives = 68/118 (57%), Gaps = 6/118 (5%)

Query: 247 RKRRAAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLN 306
           R RR  +P        LC + +  ++F  +GW  WII PK + A  C GECP  +    +
Sbjct: 234 RHRRHHLP----DRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFH 289

Query: 307 SSNYAFMQALMHAVDP-EIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
            +N+A++Q+L+    P  +P   C P K  P+SMLY DN   V+L H++DM+V+ECGC
Sbjct: 290 PTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVDNG-RVLLDHHKDMIVEECGC 346


>gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens]
          Length = 392

 Score = 91.7 bits (226), Expect = 9e-19
 Identities = 43/103 (41%), Positives = 60/103 (58%), Gaps = 1/103 (0%)

Query: 262 NLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMH-AV 320
           N C  H   I+FR LGW  WIIAP  +  NYC G C   L   LNS N+A +Q L++  V
Sbjct: 289 NQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLV 348

Query: 321 DPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
           D  +P+  C+P K  PIS+L  + N +++ + YE M+ + C C
Sbjct: 349 DQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTC 391


>gi|13899338 activin beta E [Homo sapiens]
          Length = 350

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 41/104 (39%), Positives = 65/104 (62%), Gaps = 3/104 (2%)

Query: 263 LCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTIS--LNSSNYAFMQALMHAV 320
           LC R   +++F++LGW  WI+ P+G+  NYC G+CP  L  S  + +S ++ + +L+ A 
Sbjct: 246 LCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKAN 305

Query: 321 DP-EIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
           +P     + C+PT   P+S+LY D+N NV+     DMVV+ CGC
Sbjct: 306 NPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349


>gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]
          Length = 352

 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 36/107 (33%), Positives = 61/107 (57%), Gaps = 7/107 (6%)

Query: 263 LCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDP 322
           +C R + F++FR++GWH WII P+G+  N+C G+CP  +   +     +F  A+++ +  
Sbjct: 246 MCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIA-GMPGIAASFHTAVLNLLKA 304

Query: 323 EIPQ------AVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
                     + C+PT   P+S+LY D + N++     DMVV+ CGC
Sbjct: 305 NTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351


>gi|4885259 myostatin [Homo sapiens]
          Length = 375

 Score = 85.1 bits (209), Expect = 9e-17
 Identities = 60/182 (32%), Positives = 85/182 (46%), Gaps = 22/182 (12%)

Query: 186 VAKDWNDNPRKNFGLFLEILVKEDRDSGVNFQP--EDTCARLRCSLHASLLVVTLNPDQC 243
           V ++W   P  N G+ ++ L +   D  V F    ED        L+  L V   +    
Sbjct: 211 VLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGED-------GLNPFLEVKVTDT--- 260

Query: 244 HPSRKRRA-AIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLT 302
            P R RR   +   + S ++ C R+ L ++F   GW  WIIAPK + ANYC GEC F   
Sbjct: 261 -PKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGECEFVFL 318

Query: 303 ISLNSSNYAFMQALMHAVDPEIPQA-VCIPTKLSPISMLYQDNNDNVILRHYEDMVVDEC 361
                ++      L+H  +P       C PTK+SPI+MLY +  + +I      MVVD C
Sbjct: 319 QKYPHTH------LVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRC 372

Query: 362 GC 363
           GC
Sbjct: 373 GC 374


>gi|5031613 growth differentiation factor 11 precursor [Homo
           sapiens]
          Length = 407

 Score = 78.6 bits (192), Expect = 8e-15
 Identities = 45/122 (36%), Positives = 61/122 (50%), Gaps = 18/122 (14%)

Query: 248 KRRAAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNS 307
           +R   +   + S ++ C R+ L ++F   GW  WIIAPK + ANYC G+C          
Sbjct: 297 RRNLGLDCDEHSSESRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGQC---------- 345

Query: 308 SNYAFMQALMHA--VDPEIPQA----VCIPTKLSPISMLYQDNNDNVILRHYEDMVVDEC 361
             Y FMQ   H   V    P+      C PTK+SPI+MLY ++   +I      MVVD C
Sbjct: 346 -EYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRC 404

Query: 362 GC 363
           GC
Sbjct: 405 GC 406


>gi|4885261 growth differentiation factor 9 precursor [Homo sapiens]
          Length = 454

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 32/104 (30%), Positives = 58/104 (55%), Gaps = 1/104 (0%)

Query: 261 KNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMH-A 319
           +N C  H   ++F  L W  WI+AP  +   YC G+CP ++     S  +  +Q +++  
Sbjct: 350 QNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEK 409

Query: 320 VDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
           +D  +P+  C+P K SP+S+L  + + ++  + YEDM+  +C C
Sbjct: 410 LDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453


>gi|4507465 transforming growth factor, beta 3 [Homo sapiens]
          Length = 412

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 90/386 (23%), Positives = 150/386 (38%), Gaps = 74/386 (19%)

Query: 30  LQFLGLDKAPSPQKFQPVPY-----------ILKKIFQDREAAATTGVSRDLCYVKELGV 78
           L  L L   P P     VPY           +L+++  +RE   T   +    Y KE+  
Sbjct: 48  LSKLRLTSPPEPTVMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHK 107

Query: 79  RGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAI-KEREQLTLAQLGLDLGPNSYY 137
              +          + PK I+       K+  FN+S++ K R  L  A+  +   PN   
Sbjct: 108 FDMIQGLAEHNELAVCPKGITS------KVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSS 161

Query: 138 NLGPELELALFLVQEP--------HVWGQTTPKPGKMFVLRSVPWPQGAVHFNLLDVAKD 189
               E  + LF +  P        ++ G+  P  G      +  W    + F++ D  ++
Sbjct: 162 KRN-EQRIELFQILRPDEHIAKQRYIGGKNLPTRG------TAEW----LSFDVTDTVRE 210

Query: 190 WNDNPRKNFGLFLEIL------------------VKEDRDSGVNFQPED---TCARLRCS 228
           W      N GL + I                   V E +  GV+ + +       RL+  
Sbjct: 211 WLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLKKQ 270

Query: 229 L-----HASLLVVTL----NPDQCHPSRKRRAAIPVPKLSCKNLCHRHQLFINFR-DLGW 278
                 H  L+++      NP Q    +KR         + +  C    L+I+FR DLGW
Sbjct: 271 KDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGW 330

Query: 279 HKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQA-VCIPTKLSPI 337
            KW+  PKG+ AN+C G CP+   +    + ++ +  L + ++PE   +  C+P  L P+
Sbjct: 331 -KWVHEPKGYYANFCSGPCPY---LRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPL 386

Query: 338 SMLYQDNNDNVILRHYEDMVVDECGC 363
           ++LY       +     +MVV  C C
Sbjct: 387 TILYYVGRTPKV-EQLSNMVVKSCKC 411


>gi|63025222 transforming growth factor, beta 1 [Homo sapiens]
          Length = 390

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 39/105 (37%), Positives = 58/105 (55%), Gaps = 8/105 (7%)

Query: 261 KNLCHRHQLFINFR-DLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHA 319
           KN C R QL+I+FR DLGW KWI  PKG+ AN+C G CP+  ++    + Y+ + AL + 
Sbjct: 291 KNCCVR-QLYIDFRKDLGW-KWIHEPKGYHANFCLGPCPYIWSL---DTQYSKVLALYNQ 345

Query: 320 VDPEIPQA-VCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363
            +P    A  C+P  L P+ ++Y       +     +M+V  C C
Sbjct: 346 HNPGASAAPCCVPQALEPLPIVYYVGRKPKV-EQLSNMIVRSCKC 389


>gi|153792495 growth differentiation factor 15 [Homo sapiens]
          Length = 308

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 39/150 (26%), Positives = 68/150 (45%), Gaps = 19/150 (12%)

Query: 219 EDTCARLRCSLHASLLVVTLNPDQCHPSRKRRAA----IPVPKLSCKNLCHRHQLFINFR 274
           E + AR +  LH       L P      R+ RA      P+    C   C  H +  +  
Sbjct: 172 ESSSARPQLELH-------LRPQAARGRRRARARNGDHCPLGPGRC---CRLHTVRASLE 221

Query: 275 DLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPE-IPQAVCIPTK 333
           DLGW  W+++P+      C G CP        ++ +A ++  +H + P+ +P   C+P  
Sbjct: 222 DLGWADWVLSPREVQVTMCIGACPSQFRA---ANMHAQIKTSLHRLKPDTVPAPCCVPAS 278

Query: 334 LSPISMLYQDNNDNVILRHYEDMVVDECGC 363
            +P+ +L Q  +  V L+ Y+D++  +C C
Sbjct: 279 YNPM-VLIQKTDTGVSLQTYDDLLAKDCHC 307


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.141    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,811,154
Number of Sequences: 37866
Number of extensions: 700877
Number of successful extensions: 1714
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1640
Number of HSP's gapped (non-prelim): 43
length of query: 364
length of database: 18,247,518
effective HSP length: 104
effective length of query: 260
effective length of database: 14,309,454
effective search space: 3720458040
effective search space used: 3720458040
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.