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Search of human proteins with 100816392
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|100816392 far upstream element (FUSE) binding protein 3
[Homo sapiens]
(572 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 1159 0.0
gi|17402900 far upstream element-binding protein [Homo sapiens] 608 e-174
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 535 e-152
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 88 2e-17
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 86 9e-17
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 86 9e-17
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 84 3e-16
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 82 1e-15
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 82 2e-15
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 81 3e-15
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 80 5e-15
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 79 1e-14
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 78 2e-14
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 77 3e-14
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 76 1e-13
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 75 2e-13
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 75 2e-13
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 74 5e-13
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 74 5e-13
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 74 5e-13
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 73 6e-13
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 73 6e-13
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 71 2e-12
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 69 9e-12
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 67 3e-11
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 63 6e-10
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 63 6e-10
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 63 6e-10
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 61 2e-09
gi|4885409 high density lipoprotein binding protein [Homo sapiens] 57 6e-08
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 1159 bits (2998), Expect = 0.0
Identities = 572/572 (100%), Positives = 572/572 (100%)
Query: 1 MAELVQGQSAPVGMKAEGFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPL 60
MAELVQGQSAPVGMKAEGFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPL
Sbjct: 1 MAELVQGQSAPVGMKAEGFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPL 60
Query: 61 DDGVGNQLGALVHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI 120
DDGVGNQLGALVHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI
Sbjct: 61 DDGVGNQLGALVHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI 120
Query: 121 PERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGR 180
PERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGR
Sbjct: 121 PERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGR 180
Query: 181 GGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADF 240
GGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADF
Sbjct: 181 GGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADF 240
Query: 241 RGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERA 300
RGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERA
Sbjct: 241 RGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERA 300
Query: 301 AQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYT 360
AQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYT
Sbjct: 301 AQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYT 360
Query: 361 VPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQL 420
VPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQL
Sbjct: 361 VPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQL 420
Query: 421 IDEKVGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGP 480
IDEKVGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGP
Sbjct: 421 IDEKVGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGP 480
Query: 481 PAFLTQGWGSTYQAWQQPTQQVPSQQSQPQSSQPNYSKAWEDYYKKQSHAASAAPQASSP 540
PAFLTQGWGSTYQAWQQPTQQVPSQQSQPQSSQPNYSKAWEDYYKKQSHAASAAPQASSP
Sbjct: 481 PAFLTQGWGSTYQAWQQPTQQVPSQQSQPQSSQPNYSKAWEDYYKKQSHAASAAPQASSP 540
Query: 541 PDYTMAWAEYYRQQVAFYGQTLGQAQAHSQEQ 572
PDYTMAWAEYYRQQVAFYGQTLGQAQAHSQEQ
Sbjct: 541 PDYTMAWAEYYRQQVAFYGQTLGQAQAHSQEQ 572
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 608 bits (1567), Expect = e-174
Identities = 340/617 (55%), Positives = 403/617 (65%), Gaps = 82/617 (13%)
Query: 17 EGFVDALHRVRQIAAKI--DSIPHLNNSTPLVDPSVYGYGVQKRPLDDG----------- 63
+ F DAL R RQIAAKI D+ LN++ YGYG QKRPL+DG
Sbjct: 29 DAFKDALQRARQIAAKIGGDAGTSLNSND-------YGYGGQKRPLEDGDQPDAKKVAPQ 81
Query: 64 ---VGNQLGALVHQ--RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESS 118
G QL + Q R+V+TEE+KVPD MVGFIIGRGGEQISRIQ ESGCKIQIA +S
Sbjct: 82 NDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSG 141
Query: 119 GIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVI 178
G+PER C+LTGTPES++ AKRLL QIV++ R PGFH+ + +QEI+IPASK GLVI
Sbjct: 142 GLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVI 201
Query: 179 GRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQA 238
G+GGETIKQLQER GVKMVMIQDGP TGADKPLRITGD +KVQQA+EMVLE+IR DQ
Sbjct: 202 GKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIR--DQG 259
Query: 239 DFRGVRGDFNSRMGGGS-IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP 297
FR VR ++ SR+GG I+V +PRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDG +P
Sbjct: 260 GFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP 319
Query: 298 ERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEI 357
ER AQ+ GPPDRCQHAA II++L+ + Q + G RGRGRG+G+W++G PGG+QE
Sbjct: 320 ERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEF 379
Query: 358 TYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVA 417
+ VP K GL+IGKGGE IKSI+QQSGA +ELQRNPPPN+DPN++ FTIRG PQQI+ A
Sbjct: 380 NFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYA 439
Query: 418 RQLIDEKVGG--TNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHST 475
RQLI+EK+GG LG P G P PP P + P A N P
Sbjct: 440 RQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGP---PGPGTPMGPYNPAPYNPGPPGP 496
Query: 476 PVSGPPA-FLTQGWGSTYQAWQQPTQQVPS--------------------QQSQPQSSQP 514
GPPA + QGWG+ Y WQQ P+ QQ+QP + P
Sbjct: 497 APHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAP 556
Query: 515 ------------------------NYSKAWEDYYKKQSHAASAAPQASSP---PDYTMAW 547
+Y+KAWE+YYKK A AP + P PDY+ AW
Sbjct: 557 AGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAV-PAPTGAPPGGQPDYSAAW 615
Query: 548 AEYYRQQVAFYGQTLGQ 564
AEYYRQQ A+Y QT Q
Sbjct: 616 AEYYRQQAAYYAQTSPQ 632
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 535 bits (1378), Expect = e-152
Identities = 310/638 (48%), Positives = 403/638 (63%), Gaps = 98/638 (15%)
Query: 13 GMKAEGFVDALHRVRQIAAKI--DSIPHLNNSTPLVDPSVYGYGVQKRPLDDG------- 63
G++ + F DA+ R RQIAAKI D+ +NNSTP +G+G QKR L+DG
Sbjct: 68 GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTP-----DFGFGGQKRQLEDGDQPESKK 122
Query: 64 -------VGNQLGAL-VHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIAS 115
+ +QLG + RT +TEE++VPD MVG IIGRGGEQI++IQ +SGCK+QI+
Sbjct: 123 LASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISP 182
Query: 116 ESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPG--FHNDIDS--NSTIQEILIPA 171
+S G+PER LTG PES+++AK +L IV R R GP FH++ + N T+QEI+IPA
Sbjct: 183 DSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPA 242
Query: 172 SKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEI 231
K GLVIG+GGETIKQLQER GVKM++IQDG T DKPLRI GD +KVQQA EMV++I
Sbjct: 243 GKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDI 302
Query: 232 IREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKP 291
+RE+DQ F G R ++ SR+GGG I+V VPR +VG+VIGR+GEMIKKIQNDAGVRIQFK
Sbjct: 303 LRERDQGGF-GDRNEYGSRIGGG-IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360
Query: 292 DDGISPERAAQVMGPPDRCQHAAHIISELILTAQE-----RDGFGGLAAARGRGRGRGDW 346
DDG PE+ A +MGPPDRC+HAA II++L+ + + G G RGRGRG+G+W
Sbjct: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420
Query: 347 SVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFT 406
G PGG E+T+++P KCGLVIG+GGEN+K+INQQ+GA VE+ R PPN DPN + F
Sbjct: 421 --GPPGG--EMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFI 476
Query: 407 IRGVPQQIEVARQLIDEKV-----------GGTNLGAP-GAFGQSPFSQ--PPAPPH--- 449
IRG PQQI+ A+QLI+EK+ GG P G F PF+Q P APPH
Sbjct: 477 IRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGG 536
Query: 450 --QNTFPPRSSGCF-----------PNMAAKVNGNPHST--------------PVSG--- 479
+ +PP+ G P+ AA +P++ PV G
Sbjct: 537 PPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAP 596
Query: 480 ----------PPAFLTQGWGSTYQAWQQPTQQVPSQQSQPQS-SQPNYSKAWEDYYKKQS 528
PP G +AW++ +++ Q QP + Q +Y+KAWE+YYKKQ+
Sbjct: 597 APAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQA 656
Query: 529 HAASAAPQASSP---PDYTMAWAEYYRQQVAFYGQTLG 563
A+ + P PDY+ AWAEYYRQQ A+YGQT G
Sbjct: 657 QVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPG 694
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 87.8 bits (216), Expect = 2e-17
Identities = 82/348 (23%), Positives = 150/348 (43%), Gaps = 50/348 (14%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLG---- 142
K VG IIG+ GE + +++ ESG +I I+ PER +TG ++I +A ++
Sbjct: 55 KEVGSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFE 112
Query: 143 -QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQD 201
I++ N P +++PAS+ G +IG+GG IK+++E TG + V +
Sbjct: 113 EDIINSMSNSPA----TSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQ-VQVAG 167
Query: 202 GPLPTGADKPLRITGDAFKVQQAREMVLEIIREKD----QADFRGVRGDFNSRMGGGSIE 257
LP ++ + I+G + Q + + ++ E +R GG
Sbjct: 168 DMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAY 227
Query: 258 VSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHII 317
++A+ + + + K+ A + F P +P + + P + A +++
Sbjct: 228 TIQGQYAI-----PHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKL-PLHSSEEAQNLM 281
Query: 318 SELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENI 377
+ GL A+ P E+ T+P D G +IG+ G I
Sbjct: 282 GQ----------SSGLDAS-------------PPASTHEL--TIPNDLIGCIIGRQGTKI 316
Query: 378 KSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425
I Q SGA +++ +S+ R+ TI G P I +A+ LI+ ++
Sbjct: 317 NEIRQMSGAQIKIANATEGSSE---RQITITGTPANISLAQYLINARL 361
Score = 69.3 bits (168), Expect = 9e-12
Identities = 53/181 (29%), Positives = 81/181 (44%), Gaps = 20/181 (11%)
Query: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTA 324
VG +IG+ GE +KK++ ++G RI +G PER + GP D A +I+
Sbjct: 57 VGSIIGKKGETVKKMREESGARINIS--EGNCPERIVTITGPTDAIFKAFAMIAYKF--- 111
Query: 325 QERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQS 384
E D ++ + + + VPA +CG +IGKGG IK I + +
Sbjct: 112 -EEDIINSMSNSPATSKPP-----------VTLRLVVPASQCGSLIGKGGSKIKEIREST 159
Query: 385 GAHVELQRNPPPNSDPNLRRFTIRGVPQQ-IEVARQLIDEKVGGTNLGAPGAFGQSPFSQ 443
GA V++ + PNS R TI G P I+ +Q+ + GA + P S
Sbjct: 160 GAQVQVAGDMLPNSTE--RAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPAST 217
Query: 444 P 444
P
Sbjct: 218 P 218
Score = 65.9 bits (159), Expect = 1e-10
Identities = 65/280 (23%), Positives = 116/280 (41%), Gaps = 28/280 (10%)
Query: 61 DDGVGNQLGALVHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SG 119
+D + + + + +T VP G +IG+GG +I I+ +G ++Q+A +
Sbjct: 113 EDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN 172
Query: 120 IPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIG 179
ER ++GTP++I Q + QI P +TI PAS + G
Sbjct: 173 STERAVTISGTPDAIIQCVK---QICVVMLESP------PKGATIPYRPKPASTPVIFAG 223
Query: 180 ------RGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIR 233
+G I + T + + +Q P P PL T AF ++ L +
Sbjct: 224 GQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFP-----PLGQTNPAFPGEK-----LPLHS 273
Query: 234 EKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDD 293
++ + G ++ + E+++P +G +IGR G I +I+ +G +I+
Sbjct: 274 SEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANAT 333
Query: 294 GISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGL 333
S ER + G P A ++I+ + E G G L
Sbjct: 334 EGSSERQITITGTPANISLAQYLINARL--TSEVTGMGTL 371
Score = 57.4 bits (137), Expect = 4e-08
Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 12/126 (9%)
Query: 21 DALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDG-----VGNQLGALVHQR 75
D L ++ Q+A + P L + P + +K PL + Q L
Sbjct: 239 DQLTKLHQLAMQQTPFPPLGQTNP-------AFPGEKLPLHSSEEAQNLMGQSSGLDASP 291
Query: 76 TVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIE 135
T E +P+ ++G IIGR G +I+ I+ SG +I+IA+ + G ER +TGTP +I
Sbjct: 292 PASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANIS 351
Query: 136 QAKRLL 141
A+ L+
Sbjct: 352 LAQYLI 357
Score = 52.8 bits (125), Expect = 9e-07
Identities = 39/143 (27%), Positives = 72/143 (50%), Gaps = 8/143 (5%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+ +VG +IG+ GET+K+++E +G + + I +G P ++ + ITG + +A
Sbjct: 50 LLMHGKEVGSIIGKKGETVKKMREESGAR-INISEGNCP---ERIVTITGPTDAIFKAFA 105
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M I + ++ + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 106 M---IAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQ 162
Query: 287 IQFKPDD-GISPERAAQVMGPPD 308
+Q D S ERA + G PD
Sbjct: 163 VQVAGDMLPNSTERAVTISGTPD 185
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 85.9 bits (211), Expect = 9e-17
Identities = 82/339 (24%), Positives = 146/339 (43%), Gaps = 50/339 (14%)
Query: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQI-ASESSGIPERPCVLTGTPESIEQAKRLLG 142
VP + VG IIG+ G I I ++ ++ I E+SG E+P + TPE +A R++
Sbjct: 200 VPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL 259
Query: 143 QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVM--IQ 200
+I+ + + +I +IL VG +IG+ G +K+++ TG K+ + +Q
Sbjct: 260 EIMQKEADETKLAEEIPL-----KILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQ 314
Query: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVR---GDFNSRMGGGS-- 255
D + ++ + + G A +++ +RE + D V G F+S
Sbjct: 315 DLSI-YNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFG 373
Query: 256 -------------IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGIS-PERAA 301
+ + +P AVG +IG+ G IK++ AG I+ P +G ER
Sbjct: 374 PFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMV 433
Query: 302 QVMGPPD-RCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYT 360
+ GPP+ + + I +L +E + F + E
Sbjct: 434 IITGPPEAQFKAQGRIFGKL----KEENFFNPKEEVK-----------------LEAHIR 472
Query: 361 VPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSD 399
VP+ G VIGKGG+ + + + A V + R+ P+ +
Sbjct: 473 VPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN 511
Score = 79.0 bits (193), Expect = 1e-14
Identities = 53/190 (27%), Positives = 97/190 (51%), Gaps = 10/190 (5%)
Query: 66 NQLGALVHQRTVITEEFK---VPDKMVGFIIGRGGEQISRIQAESGCKIQIA-SESSGIP 121
+Q G H + +E +P + VG IIG+ G I ++ +G I+IA +E +
Sbjct: 370 HQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS 429
Query: 122 ERPCVLTGTPESIEQAK-RLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGR 180
ER ++TG PE+ +A+ R+ G++ + F N + I +P+S G VIG+
Sbjct: 430 ERMVIITGPPEAQFKAQGRIFGKLKEE-----NFFNPKEEVKLEAHIRVPSSTAGRVIGK 484
Query: 181 GGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADF 240
GG+T+ +LQ T ++++ +D + +RI G F Q A+ + EI+++ Q +
Sbjct: 485 GGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544
Query: 241 RGVRGDFNSR 250
+ +G + R
Sbjct: 545 KYPQGVASQR 554
Score = 67.8 bits (164), Expect = 3e-11
Identities = 68/255 (26%), Positives = 113/255 (44%), Gaps = 21/255 (8%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
IL+P VG +IG+ G TIK + ++T + V I A+KP+ I +A
Sbjct: 198 ILVPTQFVGAIIGKEGLTIKNITKQTQSR-VDIHRKENSGAAEKPVTIHATPEGTSEACR 256
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M+LEI+++ +AD + + +++ VG +IG+ G +KKI+++ G +
Sbjct: 257 MILEIMQK--EADETKLAEEI-------PLKILAHNGLVGRLIGKEGRNLKKIEHETGTK 307
Query: 287 IQFKPDDGIS---PERAAQVMGPPDRCQHAAHIISELILTAQERDGFG-----GLAAARG 338
I +S PER V G + C A I + + A E D G ++
Sbjct: 308 ITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLY 367
Query: 339 RGRGRGDWSVGAPGGVQEITYT-VPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPN 397
G + QEI +P G +IGK G +IK + + +GA +++ P
Sbjct: 368 PHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA--PAEG 425
Query: 398 SDPNLRRFTIRGVPQ 412
D + R I G P+
Sbjct: 426 PDVSERMVIITGPPE 440
Score = 57.4 bits (137), Expect = 4e-08
Identities = 69/283 (24%), Positives = 119/283 (42%), Gaps = 42/283 (14%)
Query: 88 MVGFIIGRGGEQISRIQAESGCKIQIASE---SSGIPERPCVLTGTPES-----IEQAKR 139
+VG +IG+ G + +I+ E+G KI I+S S PER + GT E+ IE K+
Sbjct: 285 LVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKK 344
Query: 140 L-----------------LGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGG 182
L + + GP H+ I + IP VG +IG+ G
Sbjct: 345 LREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKG 404
Query: 183 ETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRG 242
IKQL G + I P +++ + ITG +A+ + ++E++ F
Sbjct: 405 AHIKQLARFAGAS-IKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEEN---FFN 460
Query: 243 VRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRI----QFKPDDGISPE 298
+ + + VP G VIG+ G+ + ++QN + PD+ + E
Sbjct: 461 PKEEVKLEA-----HIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDE--NEE 513
Query: 299 RAAQVMGPPDRCQHAAHIISELI--LTAQERDGFGGLAAARGR 339
+++G Q A I E++ + QE+ G+A+ R +
Sbjct: 514 VIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 556
Score = 35.4 bits (80), Expect = 0.14
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 9/81 (11%)
Query: 350 APGGVQE-------ITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNL 402
APGG + + VP G +IGK G IK+I +Q+ + V++ R NS
Sbjct: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRK--ENSGAAE 239
Query: 403 RRFTIRGVPQQIEVARQLIDE 423
+ TI P+ A ++I E
Sbjct: 240 KPVTIHATPEGTSEACRMILE 260
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 85.9 bits (211), Expect = 9e-17
Identities = 89/368 (24%), Positives = 154/368 (41%), Gaps = 52/368 (14%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
K VG IIG+ GE + +++ ESG +I I+ PER L G +I +A I+D
Sbjct: 23 KEVGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKA---FAMIID 77
Query: 147 RCRNGPGFHNDIDSNSTIQ----------EILIPASKVGLVIGRGGETIKQLQERTGVKM 196
+ DI S+ T +++PAS+ G +IG+GG IK+++E TG +
Sbjct: 78 K------LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ- 130
Query: 197 VMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREK-DQADFRGVRGDFNSRMGGGS 255
V + LP ++ + I G + + + + ++ E Q+ +GV +
Sbjct: 131 VQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYR------- 183
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPE------RAAQVMG---- 305
P+ + VI G+ +D+ P ++P+ A + G
Sbjct: 184 -----PKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAI 238
Query: 306 -PPDRCQ-HAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPA 363
PD + H + GF G+ ++ +G W + A T+P
Sbjct: 239 PQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGY--WGLDASAQTTSHELTIPN 296
Query: 364 DKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDE 423
D G +IG+ G I I Q SGA +++ ++D R+ TI G I +A+ LI+
Sbjct: 297 DLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINV 353
Query: 424 KVGGTNLG 431
++ G
Sbjct: 354 RLSSETGG 361
Score = 72.0 bits (175), Expect = 1e-12
Identities = 73/253 (28%), Positives = 106/253 (41%), Gaps = 33/253 (13%)
Query: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323
VG +IG+ GE +KK++ ++G RI +G PER + GP + A A II +L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKL--- 79
Query: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
E D + S A + VPA +CG +IGKGG IK I +
Sbjct: 80 --EEDISSSMTN-----------STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQI-----EVARQLIDEKVGGTNLGAPGAFGQ 438
+GA V++ + PNS R TI G+PQ I ++ +++ G +
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRP 184
Query: 439 SPFSQPP--APPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPP--AFLTQGWGSTYQA 494
P S P A S FP+ + NP + GPP A+ QG + Q
Sbjct: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNP---DLEGPPLEAYTIQGQYAIPQP 241
Query: 495 WQQPTQQVPSQQS 507
Q+ QQS
Sbjct: 242 DLTKLHQLAMQQS 254
Score = 49.7 bits (117), Expect = 7e-06
Identities = 74/324 (22%), Positives = 127/324 (39%), Gaps = 51/324 (15%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+ +VG +IG+ GE++K+++E +G + + I +G P ++ + + G + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEGNCP---ERIITLAGPTNAIFKAFA 73
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M+++ + E + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 74 MIIDKLEEDISSSMTNSTAASRPPV---TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 287 IQFKPDD-GISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGD 345
+Q D S ERA + G P Q + ++ + E
Sbjct: 131 VQVAGDMLPNSTERAITIAGIP---QSIIECVKQICVVMLE------------------T 169
Query: 346 WSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSD---PNL 402
S P GV I Y P VI GG++ S S + + N D P L
Sbjct: 170 LSQSPPKGV-TIPYR-PKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPL 227
Query: 403 RRFTIRG---VPQQ-----IEVARQLIDEKVGGTNLGAPGAFGQSP--------FSQPPA 446
+TI+G +PQ ++A Q + N G G SP +
Sbjct: 228 EAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQT 287
Query: 447 PPHQNTFPPRSSGC-FPNMAAKVN 469
H+ T P GC AK+N
Sbjct: 288 TSHELTIPNDLIGCIIGRQGAKIN 311
Score = 47.4 bits (111), Expect = 4e-05
Identities = 23/63 (36%), Positives = 39/63 (61%)
Query: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
+ E +P+ ++G IIGR G +I+ I+ SG +I+IA+ G +R +TG+ SI A+
Sbjct: 289 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 348
Query: 139 RLL 141
L+
Sbjct: 349 YLI 351
Score = 40.8 bits (94), Expect = 0.003
Identities = 63/280 (22%), Positives = 104/280 (37%), Gaps = 34/280 (12%)
Query: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 95 RPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
Query: 134 -IEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGE----TIKQL 188
IE K++ +++ P TI P+S VI GG+ T
Sbjct: 155 IIECVKQICVVMLETLSQSP------PKGVTIPYRPKPSSSP--VIFAGGQDRYSTGSDS 206
Query: 189 QERTGVKMVMIQDGPLPTGADKPLRITG-------DAFKVQQAREMVLEIIREKDQADFR 241
M + L + I G D K+ Q F
Sbjct: 207 ASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS 266
Query: 242 GVRGDFNSRMGGGSIEVS---------VPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KP 291
G+ G ++ S +P +G +IGR G I +I+ +G +I+ P
Sbjct: 267 GIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP 326
Query: 292 DDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFG 331
+G S +R + G A ++I+ + + E G G
Sbjct: 327 VEG-STDRQVTITGSAASISLAQYLIN--VRLSSETGGMG 363
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 84.3 bits (207), Expect = 3e-16
Identities = 88/367 (23%), Positives = 152/367 (41%), Gaps = 54/367 (14%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
K VG IIG+ GE + +++ ESG +I I+ PER L G +I +A I+D
Sbjct: 23 KEVGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKA---FAMIID 77
Query: 147 RCRNGPGFHNDIDSNSTIQ----------EILIPASKVGLVIGRGGETIKQLQERTGVKM 196
+ DI S+ T +++PAS+ G +IG+GG IK+++E TG +
Sbjct: 78 K------LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ- 130
Query: 197 VMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSI 256
V + LP ++ + I G + + + + ++ E +GV +
Sbjct: 131 VQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPP---KGVTIPYR-------- 179
Query: 257 EVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPE------RAAQVMG----- 305
P+ + VI G+ +D+ P ++P+ A + G
Sbjct: 180 ----PKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 235
Query: 306 PPDRCQ-HAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPAD 364
PD + H + GF G+ ++ +G W + A T+P D
Sbjct: 236 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGY--WGLDASAQTTSHELTIPND 293
Query: 365 KCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEK 424
G +IG+ G I I Q SGA +++ ++D R+ TI G I +A+ LI+ +
Sbjct: 294 LIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVR 350
Query: 425 VGGTNLG 431
+ G
Sbjct: 351 LSSETGG 357
Score = 75.9 bits (185), Expect = 1e-13
Identities = 75/249 (30%), Positives = 106/249 (42%), Gaps = 29/249 (11%)
Query: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323
VG +IG+ GE +KK++ ++G RI +G PER + GP + A A II +L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKL--- 79
Query: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
E D + S A + VPA +CG +IGKGG IK I +
Sbjct: 80 --EEDISSSMTN-----------STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQ-IEVARQLIDEKVGGTNLGAPGAFGQSPFS 442
+GA V++ + PNS R TI G+PQ IE +Q+ + G + P S
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184
Query: 443 QPP--APPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPP--AFLTQGWGSTYQAWQQP 498
P A S FP+ + NP + GPP A+ QG + Q
Sbjct: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNP---DLEGPPLEAYTIQGQYAIPQPDLTK 241
Query: 499 TQQVPSQQS 507
Q+ QQS
Sbjct: 242 LHQLAMQQS 250
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 8/142 (5%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+ +VG +IG+ GE++K+++E +G + + I +G P ++ + + G + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEGNCP---ERIITLAGPTNAIFKAFA 73
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M+++ + E + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 74 MIIDKLEEDISSSMTNSTAASRPPV---TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 287 IQFKPDD-GISPERAAQVMGPP 307
+Q D S ERA + G P
Sbjct: 131 VQVAGDMLPNSTERAITIAGIP 152
Score = 47.4 bits (111), Expect = 4e-05
Identities = 23/63 (36%), Positives = 39/63 (61%)
Query: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
+ E +P+ ++G IIGR G +I+ I+ SG +I+IA+ G +R +TG+ SI A+
Sbjct: 285 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 344
Query: 139 RLL 141
L+
Sbjct: 345 YLI 347
Score = 38.5 bits (88), Expect = 0.017
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 95 RPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
Query: 134 I 134
I
Sbjct: 155 I 155
Score = 33.1 bits (74), Expect = 0.71
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 255 SIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGISPERAAQVMGPPDRCQHA 313
S E+++P +G +IGR G I +I+ +G +I+ P +G S +R + G A
Sbjct: 285 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG-STDRQVTITGSAASISLA 343
Query: 314 AHIISELILTAQERDGFG 331
++I+ + + E G G
Sbjct: 344 QYLIN--VRLSSETGGMG 359
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 82.4 bits (202), Expect = 1e-15
Identities = 89/370 (24%), Positives = 156/370 (42%), Gaps = 55/370 (14%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
K VG IIG+ GE + +++ ESG +I I+ PER L G +I +A I+D
Sbjct: 23 KEVGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKA---FAMIID 77
Query: 147 RCRNGPGFHNDIDSNSTIQ----------EILIPASKVGLVIGRGGETIKQLQERTGVKM 196
+ DI S+ T +++PAS+ G +IG+GG IK+++E TG +
Sbjct: 78 K------LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ- 130
Query: 197 VMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREK-DQADFRGVRGDFNSRMGGGS 255
V + LP ++ + I G + + + + ++ E Q+ +GV +
Sbjct: 131 VQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYR------- 183
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPE------RAAQVMG---- 305
P+ + VI G+ +D+ P ++P+ A + G
Sbjct: 184 -----PKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAI 238
Query: 306 -PPDRCQ-HAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITY--TV 361
PD + H + GF G+ ++ +G + G Q ++ T+
Sbjct: 239 PQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKG---YWAGLDASAQTTSHELTI 295
Query: 362 PADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLI 421
P D G +IG+ G I I Q SGA +++ ++D R+ TI G I +A+ LI
Sbjct: 296 PNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLI 352
Query: 422 DEKVGGTNLG 431
+ ++ G
Sbjct: 353 NVRLSSETGG 362
Score = 72.0 bits (175), Expect = 1e-12
Identities = 73/253 (28%), Positives = 106/253 (41%), Gaps = 33/253 (13%)
Query: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323
VG +IG+ GE +KK++ ++G RI +G PER + GP + A A II +L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKL--- 79
Query: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
E D + S A + VPA +CG +IGKGG IK I +
Sbjct: 80 --EEDISSSMTN-----------STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQI-----EVARQLIDEKVGGTNLGAPGAFGQ 438
+GA V++ + PNS R TI G+PQ I ++ +++ G +
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRP 184
Query: 439 SPFSQPP--APPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPP--AFLTQGWGSTYQA 494
P S P A S FP+ + NP + GPP A+ QG + Q
Sbjct: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNP---DLEGPPLEAYTIQGQYAIPQP 241
Query: 495 WQQPTQQVPSQQS 507
Q+ QQS
Sbjct: 242 DLTKLHQLAMQQS 254
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 8/142 (5%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+ +VG +IG+ GE++K+++E +G + + I +G P ++ + + G + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEGNCP---ERIITLAGPTNAIFKAFA 73
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M+++ + E + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 74 MIIDKLEEDISSSMTNSTAASRPPV---TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 287 IQFKPDD-GISPERAAQVMGPP 307
+Q D S ERA + G P
Sbjct: 131 VQVAGDMLPNSTERAITIAGIP 152
Score = 47.4 bits (111), Expect = 4e-05
Identities = 23/63 (36%), Positives = 39/63 (61%)
Query: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
+ E +P+ ++G IIGR G +I+ I+ SG +I+IA+ G +R +TG+ SI A+
Sbjct: 290 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 349
Query: 139 RLL 141
L+
Sbjct: 350 YLI 352
Score = 38.5 bits (88), Expect = 0.017
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 95 RPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
Query: 134 I 134
I
Sbjct: 155 I 155
Score = 33.9 bits (76), Expect = 0.41
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 234 EKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPD 292
E + +G ++ S E+++P +G +IGR G I +I+ +G +I+ P
Sbjct: 269 ESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPV 328
Query: 293 DGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFG 331
+G S +R + G A ++I+ + + E G G
Sbjct: 329 EG-STDRQVTITGSAASISLAQYLIN--VRLSSETGGMG 364
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 81.6 bits (200), Expect = 2e-15
Identities = 91/354 (25%), Positives = 144/354 (40%), Gaps = 44/354 (12%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
K VG IIG+ GE + RI+ ESG +I I+ PER LTG +I +A ++ ++
Sbjct: 23 KEVGSIIGKKGESVKRIREESGARINISE--GNCPERIITLTGPTNAIFKAFAMIIDKLE 80
Query: 147 RCRNGPGFHNDIDSNSTIQ-EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLP 205
N ++ S + +++PA++ G +IG+GG IK+++E TG + V + LP
Sbjct: 81 EDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQ-VQVAGDMLP 139
Query: 206 TGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAV 265
++ + I G V + + + ++ E S G P A
Sbjct: 140 NSTERAITIAGVPQSVTECVKQICLVMLETLS----------QSPQGRVMTIPYQPMPAS 189
Query: 266 GIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQ--HAAHIISELILT 323
VI G+ + + AG P + GPP H IS L L
Sbjct: 190 SPVICAGGQ--DRCSDAAGY-----------PHATHDLEGPPLDAYSIQGQHTISPLDLA 236
Query: 324 ------------AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIG 371
A G G +G W+ T+P + G +IG
Sbjct: 237 KLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIG 296
Query: 372 KGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425
+ G NI I Q SGA +++ NP S R+ TI G I +A+ LI+ ++
Sbjct: 297 RQGANINEIRQMSGAQIKI-ANPVEGSSG--RQVTITGSAASISLAQYLINARL 347
Score = 73.9 bits (180), Expect = 4e-13
Identities = 74/248 (29%), Positives = 106/248 (42%), Gaps = 31/248 (12%)
Query: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323
VG +IG+ GE +K+I+ ++G RI +G PER + GP + A A II +L
Sbjct: 25 VGSIIGKKGESVKRIREESGARINIS--EGNCPERIITLTGPTNAIFKAFAMIIDKL--- 79
Query: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
E D + S A + VPA +CG +IGKGG IK I +
Sbjct: 80 --EEDINSSMTN-----------STAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRES 126
Query: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQI-EVARQLIDEKVGGTNLGAPGAFGQSPFS 442
+GA V++ + PNS R TI GVPQ + E +Q+ + + G P+
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQ 184
Query: 443 QPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHST-PVSGPP--AFLTQGWGSTYQAWQQPT 499
PA P + + G PH+T + GPP A+ QG +
Sbjct: 185 PMPAS------SPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKL 238
Query: 500 QQVPSQQS 507
QV QQS
Sbjct: 239 NQVARQQS 246
Score = 53.5 bits (127), Expect = 5e-07
Identities = 43/169 (25%), Positives = 80/169 (47%), Gaps = 27/169 (15%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+ +VG +IG+ GE++K+++E +G + + I +G P ++ + +TG + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKRIREESGAR-INISEGNCP---ERIITLTGPTNAIFKAFA 73
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGG--------SIEVSVPRFAVGIVIGRNGEMIKK 278
M+++ + E D NS M ++ + VP G +IG+ G IK+
Sbjct: 74 MIIDKLEE-----------DINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKE 122
Query: 279 IQNDAGVRIQFKPDD-GISPERAAQVMGPPDRCQHAAHIISELILTAQE 326
I+ G ++Q D S ERA + G P Q + ++ L E
Sbjct: 123 IRESTGAQVQVAGDMLPNSTERAITIAGVP---QSVTECVKQICLVMLE 168
Score = 48.1 bits (113), Expect = 2e-05
Identities = 25/66 (37%), Positives = 38/66 (57%)
Query: 76 TVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIE 135
T T E +P+ ++G IIGR G I+ I+ SG +I+IA+ G R +TG+ SI
Sbjct: 278 TQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASIS 337
Query: 136 QAKRLL 141
A+ L+
Sbjct: 338 LAQYLI 343
Score = 40.4 bits (93), Expect = 0.004
Identities = 58/260 (22%), Positives = 102/260 (39%), Gaps = 26/260 (10%)
Query: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 95 RPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQS 154
Query: 134 I-EQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERT 192
+ E K++ +++ P TI +PAS VI GG+ + +
Sbjct: 155 VTECVKQICLVMLETLSQSPQ-----GRVMTIPYQPMPASSP--VICAGGQ--DRCSDAA 205
Query: 193 GVKMVM--IQDGPLPTGADKPLRITG--DAFKVQQAREMVLEIIREKDQADFRGVRGDFN 248
G ++ PL + + D K+ Q F G+
Sbjct: 206 GYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSP 265
Query: 249 SRMG---------GGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGISPE 298
G + E+++P +G +IGR G I +I+ +G +I+ P +G S
Sbjct: 266 EVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEG-SSG 324
Query: 299 RAAQVMGPPDRCQHAAHIIS 318
R + G A ++I+
Sbjct: 325 RQVTITGSAASISLAQYLIN 344
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 80.9 bits (198), Expect = 3e-15
Identities = 88/369 (23%), Positives = 154/369 (41%), Gaps = 57/369 (15%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
K VG IIG+ GE + +++ ESG +I I+ PER L G +I +A I+D
Sbjct: 23 KEVGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKA---FAMIID 77
Query: 147 RCRNGPGFHNDIDSNSTIQ----------EILIPASKVGLVIGRGGETIKQLQERTGVKM 196
+ DI S+ T +++PAS+ G +IG+GG IK+++E TG +
Sbjct: 78 K------LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ- 130
Query: 197 VMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSI 256
V + LP ++ + I G + + + + ++ E +GV +
Sbjct: 131 VQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPP---KGVTIPYR-------- 179
Query: 257 EVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPE------RAAQVMG----- 305
P+ + VI G+ +D+ P ++P+ A + G
Sbjct: 180 ----PKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 235
Query: 306 PPDRCQ-HAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITY--TVP 362
PD + H + GF G+ ++ +G + G Q ++ T+P
Sbjct: 236 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKG---YWAGLDASAQTTSHELTIP 292
Query: 363 ADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLID 422
D G +IG+ G I I Q SGA +++ ++D R+ TI G I +A+ LI+
Sbjct: 293 NDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLIN 349
Query: 423 EKVGGTNLG 431
++ G
Sbjct: 350 VRLSSETGG 358
Score = 75.9 bits (185), Expect = 1e-13
Identities = 75/249 (30%), Positives = 106/249 (42%), Gaps = 29/249 (11%)
Query: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323
VG +IG+ GE +KK++ ++G RI +G PER + GP + A A II +L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKL--- 79
Query: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
E D + S A + VPA +CG +IGKGG IK I +
Sbjct: 80 --EEDISSSMTN-----------STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQ-IEVARQLIDEKVGGTNLGAPGAFGQSPFS 442
+GA V++ + PNS R TI G+PQ IE +Q+ + G + P S
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184
Query: 443 QPP--APPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPP--AFLTQGWGSTYQAWQQP 498
P A S FP+ + NP + GPP A+ QG + Q
Sbjct: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNP---DLEGPPLEAYTIQGQYAIPQPDLTK 241
Query: 499 TQQVPSQQS 507
Q+ QQS
Sbjct: 242 LHQLAMQQS 250
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 8/142 (5%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+ +VG +IG+ GE++K+++E +G + + I +G P ++ + + G + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEGNCP---ERIITLAGPTNAIFKAFA 73
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M+++ + E + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 74 MIIDKLEEDISSSMTNSTAASRPPV---TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 287 IQFKPDD-GISPERAAQVMGPP 307
+Q D S ERA + G P
Sbjct: 131 VQVAGDMLPNSTERAITIAGIP 152
Score = 47.4 bits (111), Expect = 4e-05
Identities = 23/63 (36%), Positives = 39/63 (61%)
Query: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
+ E +P+ ++G IIGR G +I+ I+ SG +I+IA+ G +R +TG+ SI A+
Sbjct: 286 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 345
Query: 139 RLL 141
L+
Sbjct: 346 YLI 348
Score = 38.5 bits (88), Expect = 0.017
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 95 RPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
Query: 134 I 134
I
Sbjct: 155 I 155
Score = 33.9 bits (76), Expect = 0.41
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 234 EKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPD 292
E + +G ++ S E+++P +G +IGR G I +I+ +G +I+ P
Sbjct: 265 ESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPV 324
Query: 293 DGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFG 331
+G S +R + G A ++I+ + + E G G
Sbjct: 325 EG-STDRQVTITGSAASISLAQYLIN--VRLSSETGGMG 360
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 80.1 bits (196), Expect = 5e-15
Identities = 87/368 (23%), Positives = 149/368 (40%), Gaps = 82/368 (22%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
K VG IIG+ GE + +++ ESG +I I+ PER L G +I +A I+D
Sbjct: 23 KEVGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKA---FAMIID 77
Query: 147 RCRNGPGFHNDIDSNSTIQ----------EILIPASKVGLVIGRGGETIKQLQERTGVKM 196
+ DI S+ T +++PAS+ G +IG+GG IK+++E TG +
Sbjct: 78 K------LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ- 130
Query: 197 VMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSI 256
V + LP ++ + I G + + + + ++ E ++
Sbjct: 131 VQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE--------------------TL 170
Query: 257 EVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP-----ERAAQVMG-----P 306
S P+ GV I ++P SP +A + G
Sbjct: 171 SQSPPK---------------------GVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQ 209
Query: 307 PDRCQ-HAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITY--TVPA 363
PD + H + GF G+ ++ +G + G Q ++ T+P
Sbjct: 210 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKG---YWAGLDASAQTTSHELTIPN 266
Query: 364 DKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDE 423
D G +IG+ G I I Q SGA +++ ++D R+ TI G I +A+ LI+
Sbjct: 267 DLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINV 323
Query: 424 KVGGTNLG 431
++ G
Sbjct: 324 RLSSETGG 331
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 8/142 (5%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+ +VG +IG+ GE++K+++E +G + + I +G P ++ + + G + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEGNCP---ERIITLAGPTNAIFKAFA 73
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M+++ + E + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 74 MIIDKLEEDISSSMTNSTAASRPPV---TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 287 IQFKPDD-GISPERAAQVMGPP 307
+Q D S ERA + G P
Sbjct: 131 VQVAGDMLPNSTERAITIAGIP 152
Score = 47.4 bits (111), Expect = 4e-05
Identities = 57/260 (21%), Positives = 103/260 (39%), Gaps = 24/260 (9%)
Query: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 95 RPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
Query: 134 -IEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERT 192
IE K++ +++ P TI P+S + G TI+
Sbjct: 155 IIECVKQICVVMLETLSQSP------PKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIP 208
Query: 193 GVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMG 252
+ + L + F + I E + +G ++
Sbjct: 209 QPDLTKLHQ----------LAMQQSHFPMTHGNTGFSGI--ESSSPEVKGYWAGLDASAQ 256
Query: 253 GGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGISPERAAQVMGPPDRCQ 311
S E+++P +G +IGR G I +I+ +G +I+ P +G S +R + G
Sbjct: 257 TTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG-STDRQVTITGSAASIS 315
Query: 312 HAAHIISELILTAQERDGFG 331
A ++I+ + + E G G
Sbjct: 316 LAQYLIN--VRLSSETGGMG 333
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 79.0 bits (193), Expect = 1e-14
Identities = 53/190 (27%), Positives = 97/190 (51%), Gaps = 10/190 (5%)
Query: 66 NQLGALVHQRTVITEEFK---VPDKMVGFIIGRGGEQISRIQAESGCKIQIA-SESSGIP 121
+Q G H + +E +P + VG IIG+ G I ++ +G I+IA +E +
Sbjct: 413 HQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS 472
Query: 122 ERPCVLTGTPESIEQAK-RLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGR 180
ER ++TG PE+ +A+ R+ G++ + F N + I +P+S G VIG+
Sbjct: 473 ERMVIITGPPEAQFKAQGRIFGKLKEE-----NFFNPKEEVKLEAHIRVPSSTAGRVIGK 527
Query: 181 GGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADF 240
GG+T+ +LQ T ++++ +D + +RI G F Q A+ + EI+++ Q +
Sbjct: 528 GGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587
Query: 241 RGVRGDFNSR 250
+ +G + R
Sbjct: 588 KYPQGVASQR 597
Score = 57.4 bits (137), Expect = 4e-08
Identities = 43/168 (25%), Positives = 80/168 (47%), Gaps = 9/168 (5%)
Query: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQI-ASESSGIPERPCVLTGTPESIEQAKRLLG 142
VP + VG IIG+ G I I ++ ++ I E+SG E+P + TPE +A R++
Sbjct: 200 VPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL 259
Query: 143 QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVM--IQ 200
+I+ + + +I +IL VG +IG+ G +K+++ TG K+ + +Q
Sbjct: 260 EIMQKEADETKLAEEIP-----LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQ 314
Query: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFN 248
D + ++ + + G A +++ +RE + D V N
Sbjct: 315 DLSI-YNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQAN 361
Score = 56.6 bits (135), Expect = 6e-08
Identities = 47/165 (28%), Positives = 78/165 (47%), Gaps = 13/165 (7%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
IL+P VG +IG+ G TIK + ++T + V I A+KP+ I +A
Sbjct: 198 ILVPTQFVGAIIGKEGLTIKNITKQTQSR-VDIHRKENSGAAEKPVTIHATPEGTSEACR 256
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M+LEI+++ +AD + + +++ VG +IG+ G +KKI+++ G +
Sbjct: 257 MILEIMQK--EADETKLAEEI-------PLKILAHNGLVGRLIGKEGRNLKKIEHETGTK 307
Query: 287 IQFKPDDGIS---PERAAQVMGPPDRCQHAAHIISELILTAQERD 328
I +S PER V G + C A I + + A E D
Sbjct: 308 ITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFEND 352
Score = 54.7 bits (130), Expect = 2e-07
Identities = 75/317 (23%), Positives = 123/317 (38%), Gaps = 52/317 (16%)
Query: 88 MVGFIIGRGGEQISRIQAESGCKIQIASE---SSGIPERPCVLTGTPESIEQAKRLLGQI 144
+VG +IG+ G + +I+ E+G KI I+S S PER + GT E+ A+ +I
Sbjct: 285 LVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEI---EI 341
Query: 145 VDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL 204
+ + R F ND+ + + Q LIP + +G + L G + G
Sbjct: 342 MKKLREA--FENDMLAVNQ-QANLIPGLNLS-ALGIFSTGLSVLSPPAGPR------GAP 391
Query: 205 PTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFA 264
P P F G +S + + +P A
Sbjct: 392 PAAPYHPFTTHSGYFSSLYPHHQF-------------GPFPHHHSYPEQEIVNLFIPTQA 438
Query: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGIS-PERAAQVMGPPD-RCQHAAHIISELIL 322
VG +IG+ G IK++ AG I+ P +G ER + GPP+ + + I +L
Sbjct: 439 VGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKL-- 496
Query: 323 TAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQ 382
+E + F + E VP+ G VIGKGG+ + +
Sbjct: 497 --KEENFFNPKEEVK-----------------LEAHIRVPSSTAGRVIGKGGKTVNELQN 537
Query: 383 QSGAHVELQRNPPPNSD 399
+ A V + R+ P+ +
Sbjct: 538 LTSAEVIVPRDQTPDEN 554
Score = 42.4 bits (98), Expect = 0.001
Identities = 46/195 (23%), Positives = 83/195 (42%), Gaps = 17/195 (8%)
Query: 151 GPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADK 210
GP H+ I + IP VG +IG+ G IKQL G + I P +++
Sbjct: 416 GPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGAS-IKIAPAEGPDVSER 474
Query: 211 PLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIG 270
+ ITG +A+ + ++E++ F + + + VP G VIG
Sbjct: 475 MVIITGPPEAQFKAQGRIFGKLKEEN---FFNPKEEVKLEA-----HIRVPSSTAGRVIG 526
Query: 271 RNGEMIKKIQNDAGVRI----QFKPDDGISPERAAQVMGPPDRCQHAAHIISELI--LTA 324
+ G+ + ++QN + PD+ + E +++G Q A I E++ +
Sbjct: 527 KGGKTVNELQNLTSAEVIVPRDQTPDE--NEEVIVRIIGHFFASQTAQRKIREIVQQVKQ 584
Query: 325 QERDGFGGLAAARGR 339
QE+ G+A+ R +
Sbjct: 585 QEQKYPQGVASQRSK 599
Score = 42.0 bits (97), Expect = 0.002
Identities = 60/277 (21%), Positives = 98/277 (35%), Gaps = 78/277 (28%)
Query: 241 RGVRGDFNSRMGGGS-------------IEVSVPRFAVGIVIGRNGEMIKKI--QNDAGV 285
R RGD +SR G + + + VP VG +IG+ G IK I Q + V
Sbjct: 168 RAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRV 227
Query: 286 RIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGD 345
I K + G + E+ + P+ A +I E++ +
Sbjct: 228 DIHRKENSGAA-EKPVTIHATPEGTSEACRMILEIMQKEADETKLA-------------- 272
Query: 346 WSVGAPGGVQEITYTVPADK--CGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLR 403
+EI + A G +IGK G N+K I ++G + + + R
Sbjct: 273 ---------EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPER 323
Query: 404 RFTIRGVPQ-----QIEVARQLID-------------EKVGGTNLGAPGAFG-------- 437
T++G + +IE+ ++L + + G NL A G F
Sbjct: 324 TITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSP 383
Query: 438 -QSPFSQPPAPPH----------QNTFPPRSSGCFPN 463
P PPA P+ + +P G FP+
Sbjct: 384 PAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPH 420
Score = 30.8 bits (68), Expect = 3.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 361 VPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQ 412
+P G +IGK G +IK + + +GA +++ P D + R I G P+
Sbjct: 434 IPTQAVGAIIGKKGAHIKQLARFAGASIKIA--PAEGPDVSERMVIITGPPE 483
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 78.2 bits (191), Expect = 2e-14
Identities = 87/368 (23%), Positives = 147/368 (39%), Gaps = 86/368 (23%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
K VG IIG+ GE + +++ ESG +I I+ PER L G +I +A I+D
Sbjct: 23 KEVGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKA---FAMIID 77
Query: 147 RCRNGPGFHNDIDSNSTIQ----------EILIPASKVGLVIGRGGETIKQLQERTGVKM 196
+ DI S+ T +++PAS+ G +IG+GG IK+++E TG +
Sbjct: 78 K------LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ- 130
Query: 197 VMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSI 256
V + LP ++ + I G + + + + ++ E
Sbjct: 131 VQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE---------------------- 168
Query: 257 EVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP-----ERAAQVMG-----P 306
S P+ GV I ++P SP +A + G
Sbjct: 169 --SPPK---------------------GVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQ 205
Query: 307 PDRCQ-HAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITY--TVPA 363
PD + H + GF G+ ++ +G + G Q ++ T+P
Sbjct: 206 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKG---YWAGLDASAQTTSHELTIPN 262
Query: 364 DKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDE 423
D G +IG+ G I I Q SGA +++ ++D R+ TI G I +A+ LI+
Sbjct: 263 DLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINV 319
Query: 424 KVGGTNLG 431
++ G
Sbjct: 320 RLSSETGG 327
Score = 70.9 bits (172), Expect = 3e-12
Identities = 58/182 (31%), Positives = 83/182 (45%), Gaps = 22/182 (12%)
Query: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323
VG +IG+ GE +KK++ ++G RI +G PER + GP + A A II +L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKL--- 79
Query: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
E D + S A + VPA +CG +IGKGG IK I +
Sbjct: 80 --EEDISSSMTN-----------STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQ-IEVARQLIDEKVGGTNLGAPGAFGQSPFS 442
+GA V++ + PNS R TI G+PQ IE +Q+ + G + P S
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184
Query: 443 QP 444
P
Sbjct: 185 SP 186
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 8/142 (5%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+ +VG +IG+ GE++K+++E +G + + I +G P ++ + + G + +A
Sbjct: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEGNCP---ERIITLAGPTNAIFKAFA 73
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M+++ + E + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 74 MIIDKLEEDISSSMTNSTAASRPPV---TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 287 IQFKPDD-GISPERAAQVMGPP 307
+Q D S ERA + G P
Sbjct: 131 VQVAGDMLPNSTERAITIAGIP 152
Score = 47.4 bits (111), Expect = 4e-05
Identities = 23/63 (36%), Positives = 39/63 (61%)
Query: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
+ E +P+ ++G IIGR G +I+ I+ SG +I+IA+ G +R +TG+ SI A+
Sbjct: 255 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 314
Query: 139 RLL 141
L+
Sbjct: 315 YLI 317
Score = 44.7 bits (104), Expect = 2e-04
Identities = 57/260 (21%), Positives = 103/260 (39%), Gaps = 28/260 (10%)
Query: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 95 RPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
Query: 134 -IEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERT 192
IE K++ +++ G TI P+S + G TI+
Sbjct: 155 IIECVKQICVVMLESPPKG----------VTIPYRPKPSSSPVIFAGGQAYTIQGQYAIP 204
Query: 193 GVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMG 252
+ + L + F + I E + +G ++
Sbjct: 205 QPDLTKLHQ----------LAMQQSHFPMTHGNTGFSGI--ESSSPEVKGYWAGLDASAQ 252
Query: 253 GGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGISPERAAQVMGPPDRCQ 311
S E+++P +G +IGR G I +I+ +G +I+ P +G S +R + G
Sbjct: 253 TTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG-STDRQVTITGSAASIS 311
Query: 312 HAAHIISELILTAQERDGFG 331
A ++I+ + + E G G
Sbjct: 312 LAQYLIN--VRLSSETGGMG 329
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 77.4 bits (189), Expect = 3e-14
Identities = 86/359 (23%), Positives = 145/359 (40%), Gaps = 81/359 (22%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
K VG IIG+ GE + +++ ESG +I I+ PER L G +I +A I+D
Sbjct: 23 KEVGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKA---FAMIID 77
Query: 147 RCRNGPGFHNDIDSNSTIQ----------EILIPASKVGLVIGRGGETIKQLQERTGVKM 196
+ DI S+ T +++PAS+ G +IG+GG IK+++E TG +
Sbjct: 78 K------LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ- 130
Query: 197 VMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSI 256
V + LP ++ + I G + + + + ++ E
Sbjct: 131 VQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE---------------------- 168
Query: 257 EVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA--A 314
S P+ GV I ++P SP A + Q+A
Sbjct: 169 --SPPK---------------------GVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQ 205
Query: 315 HIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITY--TVPADKCGLVIGK 372
+++L A ++ F G +S G Q ++ T+P D G +IG+
Sbjct: 206 PDLTKLHQLAMQQSHF-------PMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGR 258
Query: 373 GGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVGGTNLG 431
G I I Q SGA +++ ++D R+ TI G I +A+ LI+ ++ G
Sbjct: 259 QGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRLSSETGG 314
Score = 70.9 bits (172), Expect = 3e-12
Identities = 58/182 (31%), Positives = 83/182 (45%), Gaps = 22/182 (12%)
Query: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323
VG +IG+ GE +KK++ ++G RI +G PER + GP + A A II +L
Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKL--- 79
Query: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
E D + S A + VPA +CG +IGKGG IK I +
Sbjct: 80 --EEDISSSMTN-----------STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQ-IEVARQLIDEKVGGTNLGAPGAFGQSPFS 442
+GA V++ + PNS R TI G+PQ IE +Q+ + G + P S
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184
Query: 443 QP 444
P
Sbjct: 185 SP 186
Score = 47.4 bits (111), Expect = 4e-05
Identities = 23/63 (36%), Positives = 39/63 (61%)
Query: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
+ E +P+ ++G IIGR G +I+ I+ SG +I+IA+ G +R +TG+ SI A+
Sbjct: 242 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 301
Query: 139 RLL 141
L+
Sbjct: 302 YLI 304
Score = 38.5 bits (88), Expect = 0.017
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 95 RPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
Query: 134 I 134
I
Sbjct: 155 I 155
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 75.9 bits (185), Expect = 1e-13
Identities = 66/300 (22%), Positives = 122/300 (40%), Gaps = 62/300 (20%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLG---- 142
K VG IIG+ GE + +++ ESG +I I+ PER +TG ++I +A ++
Sbjct: 55 KEVGSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFE 112
Query: 143 -QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQD 201
I++ N P +++PAS+ G +IG+GG IK+++E TG + V +
Sbjct: 113 EDIINSMSNSPA----TSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQ-VQVAG 167
Query: 202 GPLPTGADKPLRITGDAFKVQQAREMVLEIIRE--------------------------- 234
LP ++ + I+G + Q + + ++ E
Sbjct: 168 DMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTP 227
Query: 235 ---------------------KDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNG 273
++ + G ++ + E+++P +G +IGR G
Sbjct: 228 FPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQG 287
Query: 274 EMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGL 333
I +I+ +G +I+ S ER + G P A ++I+ + E G G L
Sbjct: 288 TKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARL--TSEVTGMGTL 345
Score = 71.6 bits (174), Expect = 2e-12
Identities = 73/299 (24%), Positives = 124/299 (41%), Gaps = 53/299 (17%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+ +VG +IG+ GET+K+++E +G + + I +G P ++ + ITG + +A
Sbjct: 50 LLMHGKEVGSIIGKKGETVKKMREESGAR-INISEGNCP---ERIVTITGPTDAIFKAFA 105
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M I + ++ + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 106 M---IAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQ 162
Query: 287 IQFKPDD-GISPERAAQVMGPPDRCQHAAHIISELILTA--------------------- 324
+Q D S ERA + G PD I ++L A
Sbjct: 163 VQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLA 222
Query: 325 ----------QERDGFGG--------LAAARGRGRGRGDWSVGAPGGVQEITYTVPADKC 366
Q F G A G+ G P E+ T+P D
Sbjct: 223 MQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSG-LDASPPASTHEL--TIPNDLI 279
Query: 367 GLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425
G +IG+ G I I Q SGA +++ +S+ R+ TI G P I +A+ LI+ ++
Sbjct: 280 GCIIGRQGTKINEIRQMSGAQIKIANATEGSSE---RQITITGTPANISLAQYLINARL 335
Score = 55.5 bits (132), Expect = 1e-07
Identities = 37/124 (29%), Positives = 60/124 (48%), Gaps = 12/124 (9%)
Query: 23 LHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDG-----VGNQLGALVHQRTV 77
L ++ Q+A + P L + P + +K PL + Q L
Sbjct: 215 LTKLHQLAMQQTPFPPLGQTNP-------AFPGEKLPLHSSEEAQNLMGQSSGLDASPPA 267
Query: 78 ITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQA 137
T E +P+ ++G IIGR G +I+ I+ SG +I+IA+ + G ER +TGTP +I A
Sbjct: 268 STHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLA 327
Query: 138 KRLL 141
+ L+
Sbjct: 328 QYLI 331
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 75.1 bits (183), Expect = 2e-13
Identities = 94/423 (22%), Positives = 167/423 (39%), Gaps = 79/423 (18%)
Query: 24 HRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDGVGNQLGALVHQRTV-ITEEF 82
H++ A K+ IP + + G+G + +P G GA Q+ V I
Sbjct: 142 HQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQ-GSPVAAGAPAKQQQVDIPLRL 200
Query: 83 KVPDKMVGFIIGRGGEQISRIQAESGCKIQI-ASESSGIPERPCVLTGTPESIEQAKRLL 141
VP + VG IIG+ G I I ++ KI + E++G E+ + TPE A +++
Sbjct: 201 LVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMI 260
Query: 142 GQIVDRCRNGPGFHNDIDSNSTIQE----ILIPASKVGLVIGRGGETIKQLQERTGVKMV 197
+I+ H + T E IL + VG +IG+ G +K++++ T K+
Sbjct: 261 LEIM---------HKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKIT 311
Query: 198 M--IQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVR----------- 244
+ +QD L ++ + + G +A + +++ +RE + D +
Sbjct: 312 ISSLQDLTL-YNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNL 370
Query: 245 --------------------------GDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKK 278
F ++V +P AVG +IG+ G+ IK+
Sbjct: 371 AAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQ 430
Query: 279 IQNDAGVRIQFKPDDGI-SPERAAQVMGPPD-RCQHAAHIISELILTAQERDGFGGLAAA 336
+ A I+ P + S R + GPP+ + + I +L +E + FG
Sbjct: 431 LSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKL----KEENFFGPKEEV 486
Query: 337 RGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPP 396
+ E VPA G VIGKGG+ + + + A V + R+ P
Sbjct: 487 K-----------------LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTP 529
Query: 397 NSD 399
+ +
Sbjct: 530 DEN 532
Score = 67.4 bits (163), Expect = 3e-11
Identities = 46/169 (27%), Positives = 87/169 (51%), Gaps = 7/169 (4%)
Query: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIAS-ESSGIPERPCVLTGTPESIEQAK-RLL 141
+P + VG IIG+ G+ I ++ + I+IA E+ R ++TG PE+ +A+ R+
Sbjct: 412 IPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIY 471
Query: 142 GQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQD 201
G++ + GP ++++ I +PAS G VIG+GG+T+ +LQ T ++V+ +D
Sbjct: 472 GKLKEENFFGPKEEVKLETH-----IRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRD 526
Query: 202 GPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSR 250
++I G + Q A+ + +I+ + Q +G +R
Sbjct: 527 QTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQAR 575
Score = 63.9 bits (154), Expect = 4e-10
Identities = 69/295 (23%), Positives = 117/295 (39%), Gaps = 40/295 (13%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+P VG +IG+ G TI+ + ++T K + + A+K + + A +
Sbjct: 200 LLVPTQYVGAIIGKEGATIRNITKQTQSK-IDVHRKENAGAAEKAISVHSTPEGCSSACK 258
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M+LEI+ K+ D +++ VG +IG+ G +KK++ D +
Sbjct: 259 MILEIM-HKEAKD--------TKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 309
Query: 287 IQFKPDDGI---SPERAAQVMGPPDRCQHAAHIISELILTAQERD--------------- 328
I + +PER V G + C A I + + A E D
Sbjct: 310 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLN 369
Query: 329 -GFGGLAAARGRG--------RGRGDWSVGAPGGVQEITYT-VPADKCGLVIGKGGENIK 378
GL A G +S QE+ +PA G +IGK G++IK
Sbjct: 370 LAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIK 429
Query: 379 SINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVGGTNLGAP 433
+++ + A +++ PP D +R I G P+ A+ I K+ N P
Sbjct: 430 QLSRFASASIKIA--PPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGP 482
Score = 43.5 bits (101), Expect = 5e-04
Identities = 57/268 (21%), Positives = 103/268 (38%), Gaps = 65/268 (24%)
Query: 86 DKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI---PERPCVLTGTPESIEQAKRLLG 142
+ VG +IG+ G + +++ ++ KI I+S PER + G +IE R
Sbjct: 285 NNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKG---AIENCCRAEQ 341
Query: 143 QIVDRCRNGPGFHNDIDSNST--------------------------------------- 163
+I+ + R + ND+ + S
Sbjct: 342 EIMKKVREA--YENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSF 399
Query: 164 -------IQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITG 216
+ ++ IPA VG +IG+ G+ IKQL R + I P + + ITG
Sbjct: 400 MQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQL-SRFASASIKIAPPETPDSKVRMVIITG 458
Query: 217 DAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMI 276
+A+ + ++E+ +F G + + + VP A G VIG+ G+ +
Sbjct: 459 PPEAQFKAQGRIYGKLKEE---NFFGPKEEVKL-----ETHIRVPASAAGRVIGKGGKTV 510
Query: 277 KKIQNDAGVRIQFKPDDGISPERAAQVM 304
++QN + D +P+ QV+
Sbjct: 511 NELQNLTAAEVVVPRDQ--TPDENDQVI 536
Score = 42.4 bits (98), Expect = 0.001
Identities = 53/225 (23%), Positives = 82/225 (36%), Gaps = 46/225 (20%)
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKI--QNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA 313
+ + VP VG +IG+ G I+ I Q + + + K + G + E+A V P+ C A
Sbjct: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA-EKAISVHSTPEGCSSA 256
Query: 314 AHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADK--CGLVIG 371
+I E I+ + +D E+ + A G +IG
Sbjct: 257 CKMILE-IMHKEAKD----------------------TKTADEVPLKILAHNNFVGRLIG 293
Query: 372 KGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVG----- 426
K G N+K + Q + + + R T++G + A Q I +KV
Sbjct: 294 KEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYEN 353
Query: 427 -------------GTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSS 458
G NL A G F S + PP P P SS
Sbjct: 354 DVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 398
Score = 37.7 bits (86), Expect = 0.029
Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 10/101 (9%)
Query: 327 RDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYT----VPADKCGLVIGKGGENIKSINQ 382
R GFG +RG+ R + GAP Q++ VP G +IGK G I++I +
Sbjct: 168 RGGFG----SRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITK 223
Query: 383 QSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDE 423
Q+ + +++ R N+ + ++ P+ A ++I E
Sbjct: 224 QTQSKIDVHRK--ENAGAAEKAISVHSTPEGCSSACKMILE 262
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 74.7 bits (182), Expect = 2e-13
Identities = 88/382 (23%), Positives = 159/382 (41%), Gaps = 70/382 (18%)
Query: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQI-ASESSGIPERPCVLTGTPESIEQAKRLLG 142
VP + VG IIG+ G I I ++ KI + E++G E+ + TPE A + +
Sbjct: 202 VPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSIL 261
Query: 143 QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVM--IQ 200
+I+ + F +I +IL + VG +IG+ G +K++++ T K+ + +Q
Sbjct: 262 EIMHKEAQDIKFTEEIPL-----KILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQ 316
Query: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVR--------------GD 246
+ L ++ + + G+ +A E +++ IRE + D + G
Sbjct: 317 ELTL-YNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGL 375
Query: 247 FNSRMG-----------------------GGSIEVSVPRFAVGIVIGRNGEMIKKIQNDA 283
F G ++ + +P +VG +IG+ G+ IK++ A
Sbjct: 376 FPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFA 435
Query: 284 GVRIQFKPDDGISPE-RAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRG 342
G I+ P + + R + GPP+ AQ + A R G+
Sbjct: 436 GASIKIAPAEAPDAKVRMVIITGPPE---------------AQFK------AQGRIYGKI 474
Query: 343 RGDWSVGAPGGVQ-EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPN 401
+ + V V+ E VP+ G VIGKGG+ + + S A V + R+ P+ +
Sbjct: 475 KEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQ 534
Query: 402 LRRFTIRGVPQQIEVARQLIDE 423
+ I G +VA++ I E
Sbjct: 535 V-VVKITGHFYACQVAQRKIQE 555
Score = 65.1 bits (157), Expect = 2e-10
Identities = 81/326 (24%), Positives = 133/326 (40%), Gaps = 40/326 (12%)
Query: 136 QAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVK 195
+ +R LGQ + PG + +L+P VG +IG+ G TI+ + ++T K
Sbjct: 169 RGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSK 228
Query: 196 MVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGS 255
+ + A+K + I A + +LEI+ K+ D + F +
Sbjct: 229 -IDVHRKENAGAAEKSITILSTPEGTSAACKSILEIM-HKEAQDIK-----FTEEI---P 278
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGI---SPERAAQVMGPPDRCQH 312
+++ VG +IG+ G +KKI+ D +I P + +PER V G + C
Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338
Query: 313 AAHIISELILTAQERD-GFGGLAAARGRG------------RGRGDWSVGAPGGV----- 354
A I + I + E D L A G G + G P +
Sbjct: 339 AEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYP 398
Query: 355 ---QEITYTV----PADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTI 407
Q T TV PA G +IGK G++IK +++ +GA +++ P D +R I
Sbjct: 399 QFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIA--PAEAPDAKVRMVII 456
Query: 408 RGVPQQIEVARQLIDEKVGGTNLGAP 433
G P+ A+ I K+ N +P
Sbjct: 457 TGPPEAQFKAQGRIYGKIKEENFVSP 482
Score = 65.1 bits (157), Expect = 2e-10
Identities = 44/156 (28%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Query: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIA-SESSGIPERPCVLTGTPESIEQAK-RLL 141
+P VG IIG+ G+ I ++ +G I+IA +E+ R ++TG PE+ +A+ R+
Sbjct: 412 IPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIY 471
Query: 142 GQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQD 201
G+I + P ++++ I +P+ G VIG+GG+T+ +LQ + ++V+ +D
Sbjct: 472 GKIKEENFVSPKEEVKLEAH-----IRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRD 526
Query: 202 GPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQ 237
++ITG + Q A+ + EI+ + Q
Sbjct: 527 QTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQ 562
Score = 49.7 bits (117), Expect = 7e-06
Identities = 66/296 (22%), Positives = 113/296 (38%), Gaps = 73/296 (24%)
Query: 86 DKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI---PERPCVLTGTPESIEQAKRLLG 142
+ VG +IG+ G + +I+ ++ KI I+ PER + G E+ +A+
Sbjct: 285 NNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEE--- 341
Query: 143 QIVDRCRNGPGFHNDI-------------------------------------------- 158
+I+ + R + NDI
Sbjct: 342 EIMKKIRES--YENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQ 399
Query: 159 --DSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITG 216
S + + IPA VG +IG+ G+ IKQL G + I P + + ITG
Sbjct: 400 FEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGAS-IKIAPAEAPDAKVRMVIITG 458
Query: 217 DAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIE--VSVPRFAVGIVIGRNGE 274
+A+ + I+E+ +F S +E + VP FA G VIG+ G+
Sbjct: 459 PPEAQFKAQGRIYGKIKEE----------NFVSPKEEVKLEAHIRVPSFAAGRVIGKGGK 508
Query: 275 MIKKIQNDAGVRIQFKPDDGISPERAAQVM----GPPDRCQHAAHIISELILTAQE 326
+ ++QN + + D +P+ QV+ G CQ A I E++ ++
Sbjct: 509 TVNELQNLSSAEVVVPRDQ--TPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQ 562
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 73.6 bits (179), Expect = 5e-13
Identities = 42/157 (26%), Positives = 84/157 (53%), Gaps = 13/157 (8%)
Query: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRL 140
E +VP + V IIGR G I +++ ++G +I + +E G ER +++G P + +AK
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
Query: 141 LGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQ 200
+ QI+ ++ +++ +P VG +IGRGGETI+ + + +G K+ +
Sbjct: 115 IHQILT------------ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQ 237
+ + ++I+G +V A+ ++LE + E ++
Sbjct: 163 ESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 58.5 bits (140), Expect = 2e-08
Identities = 46/163 (28%), Positives = 80/163 (49%), Gaps = 21/163 (12%)
Query: 166 EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAR 225
E+ +P V L+IGR G IKQL+++TG ++ + + G ++ L I+G +V +A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED---VGDERVLLISGFPVQVCKAK 112
Query: 226 EMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGV 285
+ +I+ E S ++SVP+ +VG +IGR GE I+ I +G
Sbjct: 113 AAIHQILTENTPV----------------SEQLSVPQRSVGRIIGRGGETIRSICKASGA 156
Query: 286 RIQF-KPDDG-ISPERAAQVMGPPDRCQHAAHIISELILTAQE 326
+I K +G + R ++ G A H+I E + +E
Sbjct: 157 KITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 56.2 bits (134), Expect = 8e-08
Identities = 49/173 (28%), Positives = 76/173 (43%), Gaps = 36/173 (20%)
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAH 315
IE+ VP+ AV ++IGR G IK+++ G RI +D + ER + G P + A
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGDERVLLISGFPVQVCKAKA 113
Query: 316 IISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGE 375
I +++ + P Q +VP G +IG+GGE
Sbjct: 114 AIHQIL-------------------------TENTPVSEQ---LSVPQRSVGRIIGRGGE 145
Query: 376 NIKSINQQSGAHVELQRNPPPNSDPNL---RRFTIRGVPQQIEVARQLIDEKV 425
I+SI + SGA + + S+ L R I G +++ A+ LI EKV
Sbjct: 146 TIRSICKASGAKITCDK----ESEGTLLLSRLIKISGTQKEVAAAKHLILEKV 194
Score = 50.1 bits (118), Expect = 6e-06
Identities = 31/78 (39%), Positives = 42/78 (53%), Gaps = 6/78 (7%)
Query: 70 ALVHQ----RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSG--IPER 123
A +HQ T ++E+ VP + VG IIGRGGE I I SG KI ES G + R
Sbjct: 113 AAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSR 172
Query: 124 PCVLTGTPESIEQAKRLL 141
++GT + + AK L+
Sbjct: 173 LIKISGTQKEVAAAKHLI 190
Score = 35.8 bits (81), Expect = 0.11
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Query: 356 EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIE 415
EI VP + L+IG+ G NIK + +Q+GA +++ + R I G P Q+
Sbjct: 54 EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE----RVLLISGFPVQVC 109
Query: 416 VARQLIDE 423
A+ I +
Sbjct: 110 KAKAAIHQ 117
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 73.6 bits (179), Expect = 5e-13
Identities = 42/157 (26%), Positives = 84/157 (53%), Gaps = 13/157 (8%)
Query: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRL 140
E +VP + V IIGR G I +++ ++G +I + +E G ER +++G P + +AK
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
Query: 141 LGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQ 200
+ QI+ ++ +++ +P VG +IGRGGETI+ + + +G K+ +
Sbjct: 115 IHQILT------------ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQ 237
+ + ++I+G +V A+ ++LE + E ++
Sbjct: 163 ESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 58.5 bits (140), Expect = 2e-08
Identities = 46/163 (28%), Positives = 80/163 (49%), Gaps = 21/163 (12%)
Query: 166 EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAR 225
E+ +P V L+IGR G IKQL+++TG ++ + + G ++ L I+G +V +A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED---VGDERVLLISGFPVQVCKAK 112
Query: 226 EMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGV 285
+ +I+ E S ++SVP+ +VG +IGR GE I+ I +G
Sbjct: 113 AAIHQILTENTPV----------------SEQLSVPQRSVGRIIGRGGETIRSICKASGA 156
Query: 286 RIQF-KPDDG-ISPERAAQVMGPPDRCQHAAHIISELILTAQE 326
+I K +G + R ++ G A H+I E + +E
Sbjct: 157 KITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 56.2 bits (134), Expect = 8e-08
Identities = 49/173 (28%), Positives = 76/173 (43%), Gaps = 36/173 (20%)
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAH 315
IE+ VP+ AV ++IGR G IK+++ G RI +D + ER + G P + A
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGDERVLLISGFPVQVCKAKA 113
Query: 316 IISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGE 375
I +++ + P Q +VP G +IG+GGE
Sbjct: 114 AIHQIL-------------------------TENTPVSEQ---LSVPQRSVGRIIGRGGE 145
Query: 376 NIKSINQQSGAHVELQRNPPPNSDPNL---RRFTIRGVPQQIEVARQLIDEKV 425
I+SI + SGA + + S+ L R I G +++ A+ LI EKV
Sbjct: 146 TIRSICKASGAKITCDK----ESEGTLLLSRLIKISGTQKEVAAAKHLILEKV 194
Score = 50.1 bits (118), Expect = 6e-06
Identities = 31/78 (39%), Positives = 42/78 (53%), Gaps = 6/78 (7%)
Query: 70 ALVHQ----RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSG--IPER 123
A +HQ T ++E+ VP + VG IIGRGGE I I SG KI ES G + R
Sbjct: 113 AAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSR 172
Query: 124 PCVLTGTPESIEQAKRLL 141
++GT + + AK L+
Sbjct: 173 LIKISGTQKEVAAAKHLI 190
Score = 35.8 bits (81), Expect = 0.11
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Query: 356 EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIE 415
EI VP + L+IG+ G NIK + +Q+GA +++ + R I G P Q+
Sbjct: 54 EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE----RVLLISGFPVQVC 109
Query: 416 VARQLIDE 423
A+ I +
Sbjct: 110 KAKAAIHQ 117
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 73.6 bits (179), Expect = 5e-13
Identities = 42/157 (26%), Positives = 84/157 (53%), Gaps = 13/157 (8%)
Query: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRL 140
E +VP + V IIGR G I +++ ++G +I + +E G ER +++G P + +AK
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
Query: 141 LGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQ 200
+ QI+ ++ +++ +P VG +IGRGGETI+ + + +G K+ +
Sbjct: 115 IHQILT------------ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQ 237
+ + ++I+G +V A+ ++LE + E ++
Sbjct: 163 ESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 58.5 bits (140), Expect = 2e-08
Identities = 46/163 (28%), Positives = 80/163 (49%), Gaps = 21/163 (12%)
Query: 166 EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAR 225
E+ +P V L+IGR G IKQL+++TG ++ + + G ++ L I+G +V +A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED---VGDERVLLISGFPVQVCKAK 112
Query: 226 EMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGV 285
+ +I+ E S ++SVP+ +VG +IGR GE I+ I +G
Sbjct: 113 AAIHQILTENTPV----------------SEQLSVPQRSVGRIIGRGGETIRSICKASGA 156
Query: 286 RIQF-KPDDG-ISPERAAQVMGPPDRCQHAAHIISELILTAQE 326
+I K +G + R ++ G A H+I E + +E
Sbjct: 157 KITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 56.2 bits (134), Expect = 8e-08
Identities = 49/173 (28%), Positives = 76/173 (43%), Gaps = 36/173 (20%)
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAH 315
IE+ VP+ AV ++IGR G IK+++ G RI +D + ER + G P + A
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGDERVLLISGFPVQVCKAKA 113
Query: 316 IISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGE 375
I +++ + P Q +VP G +IG+GGE
Sbjct: 114 AIHQIL-------------------------TENTPVSEQ---LSVPQRSVGRIIGRGGE 145
Query: 376 NIKSINQQSGAHVELQRNPPPNSDPNL---RRFTIRGVPQQIEVARQLIDEKV 425
I+SI + SGA + + S+ L R I G +++ A+ LI EKV
Sbjct: 146 TIRSICKASGAKITCDK----ESEGTLLLSRLIKISGTQKEVAAAKHLILEKV 194
Score = 50.1 bits (118), Expect = 6e-06
Identities = 31/78 (39%), Positives = 42/78 (53%), Gaps = 6/78 (7%)
Query: 70 ALVHQ----RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSG--IPER 123
A +HQ T ++E+ VP + VG IIGRGGE I I SG KI ES G + R
Sbjct: 113 AAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSR 172
Query: 124 PCVLTGTPESIEQAKRLL 141
++GT + + AK L+
Sbjct: 173 LIKISGTQKEVAAAKHLI 190
Score = 35.8 bits (81), Expect = 0.11
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Query: 356 EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIE 415
EI VP + L+IG+ G NIK + +Q+GA +++ + R I G P Q+
Sbjct: 54 EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE----RVLLISGFPVQVC 109
Query: 416 VARQLIDE 423
A+ I +
Sbjct: 110 KAKAAIHQ 117
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 73.2 bits (178), Expect = 6e-13
Identities = 85/333 (25%), Positives = 132/333 (39%), Gaps = 62/333 (18%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+ +VG +IG+ GET+K+++E++ + + I +G P ++ ITG V A
Sbjct: 22 MLMHGKEVGSIIGKKGETVKRIREQSSAR-ITISEGSCP---ERITTITGSTAAVFHAVS 77
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M I + D+ N ++ + +P G +IG+ G IK+I+ G +
Sbjct: 78 M---IAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQ 134
Query: 287 IQFKPD-DGISPERAAQVMGPPDRCQHAAHIISELILTAQERD---------GFGGLAAA 336
+Q D S ERA V G PD I +IL + + G + +
Sbjct: 135 VQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLS 194
Query: 337 RGRGRG-RGDWSVGAPGGVQEI----------------------------TYTVPADKCG 367
+G +G + P V ++ + VP D G
Sbjct: 195 ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIG 254
Query: 368 LVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLI------ 421
VIG+ G I I Q SGAH+++ + R TI G P I +A+ LI
Sbjct: 255 CVIGRQGSKISEIRQMSGAHIKIGNQAEGAGE---RHVTITGSPVSIALAQYLITACLET 311
Query: 422 -DEKVGGTNLGAPGAFGQSPFSQ-----PPAPP 448
GGT AP +PFS P APP
Sbjct: 312 AKSTSGGTPSSAPADL-PAPFSPPLTALPTAPP 343
Score = 65.1 bits (157), Expect = 2e-10
Identities = 69/297 (23%), Positives = 125/297 (42%), Gaps = 60/297 (20%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
K VG IIG+ GE + RI+ +S +I I+ S PER +TG+ ++ A ++ +D
Sbjct: 27 KEVGSIIGKKGETVKRIREQSSARITISEGSC--PERITTITGSTAAVFHAVSMIAFKLD 84
Query: 147 R--CRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL 204
C P ++ ++IPAS+ G +IG+ G IK+++E TG + V + L
Sbjct: 85 EDLCA-APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQ-VQVAGDLL 142
Query: 205 PTGADKPLRITG--DA--FKVQQAREMVLE------------------IIREKDQADFRG 242
P ++ + ++G DA V+Q ++LE ++ +Q
Sbjct: 143 PNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQG--FS 200
Query: 243 VRGDFNS----------RMGGGSIEVSVPRFAVGI--------------------VIGRN 272
V+G + + ++ ++ + P G+ VIGR
Sbjct: 201 VQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQ 260
Query: 273 GEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDG 329
G I +I+ +G I+ + ER + G P A ++I+ + TA+ G
Sbjct: 261 GSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSG 317
Score = 56.2 bits (134), Expect = 8e-08
Identities = 27/75 (36%), Positives = 47/75 (62%)
Query: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
++EF VP+ ++G +IGR G +IS I+ SG I+I +++ G ER +TG+P SI A+
Sbjct: 243 SQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQ 302
Query: 139 RLLGQIVDRCRNGPG 153
L+ ++ ++ G
Sbjct: 303 YLITACLETAKSTSG 317
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 73.2 bits (178), Expect = 6e-13
Identities = 85/333 (25%), Positives = 132/333 (39%), Gaps = 62/333 (18%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+L+ +VG +IG+ GET+K+++E++ + + I +G P ++ ITG V A
Sbjct: 22 MLMHGKEVGSIIGKKGETVKRIREQSSAR-ITISEGSCP---ERITTITGSTAAVFHAVS 77
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
M I + D+ N ++ + +P G +IG+ G IK+I+ G +
Sbjct: 78 M---IAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQ 134
Query: 287 IQFKPD-DGISPERAAQVMGPPDRCQHAAHIISELILTAQERD---------GFGGLAAA 336
+Q D S ERA V G PD I +IL + + G + +
Sbjct: 135 VQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLS 194
Query: 337 RGRGRG-RGDWSVGAPGGVQEI----------------------------TYTVPADKCG 367
+G +G + P V ++ + VP D G
Sbjct: 195 ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIG 254
Query: 368 LVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLI------ 421
VIG+ G I I Q SGAH+++ + R TI G P I +A+ LI
Sbjct: 255 CVIGRQGSKISEIRQMSGAHIKIGNQAEGAGE---RHVTITGSPVSIALAQYLITACLET 311
Query: 422 -DEKVGGTNLGAPGAFGQSPFSQ-----PPAPP 448
GGT AP +PFS P APP
Sbjct: 312 AKSTSGGTPSSAPADL-PAPFSPPLTALPTAPP 343
Score = 65.1 bits (157), Expect = 2e-10
Identities = 69/297 (23%), Positives = 125/297 (42%), Gaps = 60/297 (20%)
Query: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
K VG IIG+ GE + RI+ +S +I I+ S PER +TG+ ++ A ++ +D
Sbjct: 27 KEVGSIIGKKGETVKRIREQSSARITISEGSC--PERITTITGSTAAVFHAVSMIAFKLD 84
Query: 147 R--CRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL 204
C P ++ ++IPAS+ G +IG+ G IK+++E TG + V + L
Sbjct: 85 EDLCA-APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQ-VQVAGDLL 142
Query: 205 PTGADKPLRITG--DA--FKVQQAREMVLE------------------IIREKDQADFRG 242
P ++ + ++G DA V+Q ++LE ++ +Q
Sbjct: 143 PNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQG--FS 200
Query: 243 VRGDFNS----------RMGGGSIEVSVPRFAVGI--------------------VIGRN 272
V+G + + ++ ++ + P G+ VIGR
Sbjct: 201 VQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQ 260
Query: 273 GEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDG 329
G I +I+ +G I+ + ER + G P A ++I+ + TA+ G
Sbjct: 261 GSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSG 317
Score = 56.2 bits (134), Expect = 8e-08
Identities = 27/75 (36%), Positives = 47/75 (62%)
Query: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
++EF VP+ ++G +IGR G +IS I+ SG I+I +++ G ER +TG+P SI A+
Sbjct: 243 SQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQ 302
Query: 139 RLLGQIVDRCRNGPG 153
L+ ++ ++ G
Sbjct: 303 YLITACLETAKSTSG 317
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 71.2 bits (173), Expect = 2e-12
Identities = 62/240 (25%), Positives = 105/240 (43%), Gaps = 20/240 (8%)
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312
++V +P +A G +IG+ G+ I ++Q + G I+ P ER + G +
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 313 AAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGK 372
I+E I R+ +A + +V P ++++ VP GL+IGK
Sbjct: 112 VHGFIAEKI-----REMPQNVAKTEPVSILQPQTTVN-PDRIKQVKIIVPNSTAGLIIGK 165
Query: 373 GGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV------- 425
GG +K++ +QSGA V+L + P + R T+ G P+Q A +LI +K+
Sbjct: 166 GGATVKAVMEQSGAWVQLSQK-PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
Query: 426 GGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPPAFLT 485
N+ G S P P+ NT + AA + G+ + V+ PA L+
Sbjct: 225 SCLNISYANVTGPVANSNPTGSPYANTAEVLPTAA---AAAGLLGHANLAGVAAFPAVLS 281
Score = 70.1 bits (170), Expect = 5e-12
Identities = 45/171 (26%), Positives = 88/171 (51%), Gaps = 19/171 (11%)
Query: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESS---GIPERPCVLTGTPESIEQAKRL 140
+P G IIG+GG+ I ++Q E+G I+++ G ER C++ GT E++
Sbjct: 56 IPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVH-- 113
Query: 141 LGQIVDRCRNGPGFHNDIDSNSTIQ-------------EILIPASKVGLVIGRGGETIKQ 187
G I ++ R P + S +Q +I++P S GL+IG+GG T+K
Sbjct: 114 -GFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKA 172
Query: 188 LQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQA 238
+ E++G + + Q ++ + ++G+ + ++A E++++ I+E Q+
Sbjct: 173 VMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQS 223
Score = 59.7 bits (143), Expect = 7e-09
Identities = 43/167 (25%), Positives = 78/167 (46%), Gaps = 13/167 (7%)
Query: 166 EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL-PTGADKPLRITG-------- 216
++LIP+ G +IG+GG+TI QLQ+ TG + + + P ++ I G
Sbjct: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
Query: 217 DAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMI 276
F ++ REM + + + + + R+ +++ VP G++IG+ G +
Sbjct: 113 HGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRI--KQVKIIVPNSTAGLIIGKGGATV 170
Query: 277 KKIQNDAGVRIQF--KPDDGISPERAAQVMGPPDRCQHAAHIISELI 321
K + +G +Q KPD ER V G P++ + A +I + I
Sbjct: 171 KAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKI 217
Score = 47.0 bits (110), Expect = 5e-05
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%)
Query: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIP---ERPCVLTGTPESIEQA 137
E VP+ +VG I+G+GG+ + Q +G +IQI+ + +P R +TGTP + + A
Sbjct: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
Query: 138 KRLLGQ 143
+ L+ Q
Sbjct: 461 QYLITQ 466
Score = 46.2 bits (108), Expect = 8e-05
Identities = 23/81 (28%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 153 GFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGP-LPTGADKP 211
G D + + EI +P + VG ++G+GG+T+ + QE TG ++ + + G +P ++
Sbjct: 388 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 447
Query: 212 LRITGDAFKVQQAREMVLEII 232
+ ITG Q A+ ++ + I
Sbjct: 448 VTITGTPAATQAAQYLITQRI 468
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 55 VQKRPLDDGVGNQLGALVHQRTVITEEFK-----VPDKMVGFIIGRGGEQISRIQAESGC 109
+++ P + + L Q TV + K VP+ G IIG+GG + + +SG
Sbjct: 120 IREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGA 179
Query: 110 KIQIASESSGI--PERPCVLTGTPESIEQAKRLLGQ 143
+Q++ + GI ER ++G PE +A L+ Q
Sbjct: 180 WVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQ 215
Score = 40.0 bits (92), Expect = 0.006
Identities = 18/74 (24%), Positives = 36/74 (48%)
Query: 352 GGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVP 411
G + VP + G ++GKGG+ + + +GA +++ + R+ TI G P
Sbjct: 395 GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTP 454
Query: 412 QQIEVARQLIDEKV 425
+ A+ LI +++
Sbjct: 455 AATQAAQYLITQRI 468
Score = 38.1 bits (87), Expect = 0.022
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312
+E++VP VG ++G+ G+ + + Q G RIQ P R + G P Q
Sbjct: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
Query: 313 AAHIISELILTAQ 325
A ++I++ I Q
Sbjct: 460 AQYLITQRITYEQ 472
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 69.3 bits (168), Expect = 9e-12
Identities = 41/168 (24%), Positives = 86/168 (51%), Gaps = 13/168 (7%)
Query: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESS---GIPERPCVLTGTPESIEQAKRL 140
+P G IIG+GG+ I ++Q E+G I+++ G ER C++ GT E++
Sbjct: 39 IPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSF 98
Query: 141 LGQIV---DRCRNGPGFHNDIDSNSTIQ-------EILIPASKVGLVIGRGGETIKQLQE 190
+ + V + P N + +T+ ++++P S GL+IG+GG T+K + E
Sbjct: 99 IAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVME 158
Query: 191 RTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQA 238
++G + + Q ++ + ++G+ +V +A +++ ++E Q+
Sbjct: 159 QSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQS 206
Score = 64.7 bits (156), Expect = 2e-10
Identities = 58/236 (24%), Positives = 95/236 (40%), Gaps = 47/236 (19%)
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312
++V +P +A G +IG+ G+ I ++Q + G I+ P ER V G +
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 313 AAHIISELILT---AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLV 369
I+E + A + + + + P ++ VP GL+
Sbjct: 95 VHSFIAEKVREIPQAMTKPEVVNILQPQ---------TTMNPDRAKQAKLIVPNSTAGLI 145
Query: 370 IGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVGGTN 429
IGKGG +K++ +QSGA V+L + P + R T+ G P+Q+ A I +KV
Sbjct: 146 IGKGGATVKAVMEQSGAWVQLSQK-PEGINLQERVVTVSGEPEQVHKAVSAIVQKV---- 200
Query: 430 LGAPGAFGQSPFSQPPAPPHQNTFPPRSSGC----FPNMAAKV-NGNPHSTPVSGP 480
P+SS C + N+A V N NP +P + P
Sbjct: 201 ----------------------QEDPQSSSCLNISYANVAGPVANSNPTGSPYASP 234
Score = 60.1 bits (144), Expect = 5e-09
Identities = 58/247 (23%), Positives = 100/247 (40%), Gaps = 26/247 (10%)
Query: 131 PESIEQAKRLLG---QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQ 187
PE+ + KR L ++V R+ G + ++LIP+ G +IG+GG+TI Q
Sbjct: 3 PEAPDSRKRPLETPPEVVCTKRSNTG-----EEGEYFLKVLIPSYAAGSIIGKGGQTIVQ 57
Query: 188 LQERTGVKMVMIQDGPL-PTGADKPLRITGDAFKVQQAREMVLEIIREKDQA-------D 239
LQ+ TG + + + P ++ + G A + + E +RE QA +
Sbjct: 58 LQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVN 117
Query: 240 FRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF--KPDDGISP 297
+ N ++ VP G++IG+ G +K + +G +Q KP+
Sbjct: 118 ILQPQTTMNPDR-AKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQ 176
Query: 298 ERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEI 357
ER V G P++ A I + + + ++ A G G+P
Sbjct: 177 ERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSP------ 230
Query: 358 TYTVPAD 364
Y PAD
Sbjct: 231 -YASPAD 236
Score = 58.9 bits (141), Expect = 1e-08
Identities = 76/373 (20%), Positives = 128/373 (34%), Gaps = 63/373 (16%)
Query: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI--PERPCVLTGTPESIEQAKRLL 141
VP+ G IIG+GG + + +SG +Q++ + GI ER ++G PE + +A +
Sbjct: 137 VPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA---V 193
Query: 142 GQIVDRCRNGPGFHNDID------------SNSTIQEILIPASKVGLVIGRGGETIKQLQ 189
IV + + P + ++ SN T PA + L
Sbjct: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASGLL 253
Query: 190 ERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNS 249
G+ V LP + L A + G +
Sbjct: 254 GPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASY-------------------GYNTN 294
Query: 250 RMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDR 309
+G G + + G N A + + + G P A PP
Sbjct: 295 SLGLGLNSAAASGVLAAVAAGANPAAAAA----ANLLASYAGEAGAGPAGGAAPPPPPPP 350
Query: 310 CQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDW-----SVGAPGGV---------- 354
+ + A +G+ G A G G G G + GA GG
Sbjct: 351 GALGSFAL------AAAANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAES 404
Query: 355 --QEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQ 412
+ + VP + G ++GKGG+ + + +GA +++ + RR TI G P
Sbjct: 405 AKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPA 464
Query: 413 QIEVARQLIDEKV 425
+ A+ LI ++V
Sbjct: 465 ATQAAQYLISQRV 477
Score = 45.8 bits (107), Expect = 1e-04
Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 3/68 (4%)
Query: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIP---ERPCVLTGTPESIEQA 137
E VP+ +VG I+G+GG+ + Q +G +IQI+ + +P R +TG+P + + A
Sbjct: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
Query: 138 KRLLGQIV 145
+ L+ Q V
Sbjct: 470 QYLISQRV 477
Score = 44.7 bits (104), Expect = 2e-04
Identities = 26/95 (27%), Positives = 52/95 (54%), Gaps = 6/95 (6%)
Query: 159 DSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGP-LPTGADKPLRITGD 217
+S + EI +P + VG ++G+GG+T+ + QE TG ++ + + G LP ++ + ITG
Sbjct: 403 ESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGS 462
Query: 218 AFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMG 252
Q A+ ++ + + + +GVR ++G
Sbjct: 463 PAATQAAQYLISQRVTYE-----QGVRASNPQKVG 492
Score = 38.9 bits (89), Expect = 0.013
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312
+E++VP VG ++G+ G+ + + Q G RIQ P R + G P Q
Sbjct: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
Query: 313 AAHIISELILTAQ 325
A ++IS+ + Q
Sbjct: 469 AQYLISQRVTYEQ 481
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 67.4 bits (163), Expect = 3e-11
Identities = 46/169 (27%), Positives = 87/169 (51%), Gaps = 7/169 (4%)
Query: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIAS-ESSGIPERPCVLTGTPESIEQAK-RLL 141
+P + VG IIG+ G+ I ++ + I+IA E+ R ++TG PE+ +A+ R+
Sbjct: 273 IPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIY 332
Query: 142 GQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQD 201
G++ + GP ++++ I +PAS G VIG+GG+T+ +LQ T ++V+ +D
Sbjct: 333 GKLKEENFFGPKEEVKLETH-----IRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRD 387
Query: 202 GPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSR 250
++I G + Q A+ + +I+ + Q +G +R
Sbjct: 388 QTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQAR 436
Score = 52.4 bits (124), Expect = 1e-06
Identities = 74/321 (23%), Positives = 123/321 (38%), Gaps = 80/321 (24%)
Query: 86 DKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI---PERPCVLTGTPESIEQAKRLLG 142
+ VG +IG+ G + +++ ++ KI I+S PER + G +IE R
Sbjct: 146 NNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKG---AIENCCRAEQ 202
Query: 143 QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDG 202
+I+ + R + ND+ + S +Q LIP + V G+
Sbjct: 203 EIMKKVREA--YENDVAAMS-LQSHLIPGLNLAAV---------------GLFPASSSAV 244
Query: 203 PLPTGADKPLRITGDA--FKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSV 260
P P P +TG A QA E + ++V +
Sbjct: 245 PPP-----PSSVTGAAPYSSFMQAPEQEM--------------------------VQVFI 273
Query: 261 PRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGI-SPERAAQVMGPPD-RCQHAAHIIS 318
P AVG +IG+ G+ IK++ A I+ P + S R + GPP+ + + I
Sbjct: 274 PAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYG 333
Query: 319 ELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIK 378
+L +E + FG + E VPA G VIGKGG+ +
Sbjct: 334 KL----KEENFFGPKEEVK-----------------LETHIRVPASAAGRVIGKGGKTVN 372
Query: 379 SINQQSGAHVELQRNPPPNSD 399
+ + A V + R+ P+ +
Sbjct: 373 ELQNLTAAEVVVPRDQTPDEN 393
Score = 32.3 bits (72), Expect = 1.2
Identities = 29/110 (26%), Positives = 40/110 (36%), Gaps = 18/110 (16%)
Query: 367 GLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVG 426
G +IGK G N+K + Q + + + R T++G + A Q I +KV
Sbjct: 150 GRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVR 209
Query: 427 ------------------GTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSS 458
G NL A G F S + PP P P SS
Sbjct: 210 EAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 63.2 bits (152), Expect = 6e-10
Identities = 108/451 (23%), Positives = 166/451 (36%), Gaps = 98/451 (21%)
Query: 57 KRPLDDGVGNQLGALVHQRTVITE-EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIAS 115
KRP +D Q + E + K G +IG+GG+ I ++ + + +
Sbjct: 21 KRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP- 79
Query: 116 ESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNG-----PGFHNDIDSNSTIQE---- 166
+SSG PER ++ E+I + +L +I+ G P + + S E
Sbjct: 80 DSSG-PERILSISADIETIGE---ILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNY 135
Query: 167 -------------ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLR 213
+LI S G +IG G IK+L+E T + + Q+ P D+ +
Sbjct: 136 QHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC-CPHSTDRVVL 194
Query: 214 ITGDAFKVQQAREMVLEIIREK---------------DQADFRGVRGDFNSRMGGGSIEV 258
I G +V + +++L++I E + D+ G F+ R G V
Sbjct: 195 IGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGR---PV 251
Query: 259 SVPRFAVG----IVIGRNGEMIKKIQND--------------------AGVRIQFKPDDG 294
P G + GR G + + D G R + P
Sbjct: 252 GFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPP 311
Query: 295 ISPERAAQVMG------PPDRCQ-----HAAHIISELILT--------AQERDGFGGLAA 335
P R +M P DR A I T A E G G
Sbjct: 312 PPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDY 371
Query: 336 ARGRGRGRGDWSVGAPGG-VQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNP 394
+ GRG S G GG + T+P D G +IGKGG+ IK I +SGA +++
Sbjct: 372 SYAGGRG----SYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPL 427
Query: 395 PPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425
+ D R TI G QI+ A+ L+ V
Sbjct: 428 EGSED---RIITITGTQDQIQNAQYLLQNSV 455
Score = 55.1 bits (131), Expect = 2e-07
Identities = 28/78 (35%), Positives = 45/78 (57%)
Query: 77 VITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQ 136
+IT + +P + G IIG+GG++I +I+ ESG I+I G +R +TGT + I+
Sbjct: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQN 446
Query: 137 AKRLLGQIVDRCRNGPGF 154
A+ LL V + + GF
Sbjct: 447 AQYLLQNSVKQYADVEGF 464
Score = 47.8 bits (112), Expect = 3e-05
Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 151 GPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADK 210
G G + D+ ++ IP G +IG+GG+ IKQ++ +G + + D PL D+
Sbjct: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDR 433
Query: 211 PLRITGDAFKVQQAREMVLEIIREKDQADFRG 242
+ ITG ++Q A+ ++ + K AD G
Sbjct: 434 IITITGTQDQIQNAQYLLQNSV--KQYADVEG 463
Score = 46.2 bits (108), Expect = 8e-05
Identities = 27/94 (28%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 240 FRGVRGDFNSRMGGGSI--EVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGIS 296
+ G RG + +GG I +V++P+ G +IG+ G+ IK+I++++G I+ +P +G S
Sbjct: 373 YAGGRGSYGD-LGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG-S 430
Query: 297 PERAAQVMGPPDRCQHAAHIISELILTAQERDGF 330
+R + G D+ Q+A +++ + + +GF
Sbjct: 431 EDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF 464
Score = 35.4 bits (80), Expect = 0.14
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 356 EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQI- 414
E+ + + G VIGKGG+NIK++ A V + P +S P R +I + I
Sbjct: 44 ELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV----PDSSGPE-RILSISADIETIG 98
Query: 415 EVARQLIDEKVGGTNLGAPGAFGQSP 440
E+ +++I G L +P A Q P
Sbjct: 99 EILKKIIPTLEEGLQLPSPTATSQLP 124
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 63.2 bits (152), Expect = 6e-10
Identities = 108/451 (23%), Positives = 166/451 (36%), Gaps = 98/451 (21%)
Query: 57 KRPLDDGVGNQLGALVHQRTVITE-EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIAS 115
KRP +D Q + E + K G +IG+GG+ I ++ + + +
Sbjct: 21 KRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP- 79
Query: 116 ESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNG-----PGFHNDIDSNSTIQE---- 166
+SSG PER ++ E+I + +L +I+ G P + + S E
Sbjct: 80 DSSG-PERILSISADIETIGE---ILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNY 135
Query: 167 -------------ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLR 213
+LI S G +IG G IK+L+E T + + Q+ P D+ +
Sbjct: 136 QHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC-CPHSTDRVVL 194
Query: 214 ITGDAFKVQQAREMVLEIIREK---------------DQADFRGVRGDFNSRMGGGSIEV 258
I G +V + +++L++I E + D+ G F+ R G V
Sbjct: 195 IGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGR---PV 251
Query: 259 SVPRFAVG----IVIGRNGEMIKKIQND--------------------AGVRIQFKPDDG 294
P G + GR G + + D G R + P
Sbjct: 252 GFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPP 311
Query: 295 ISPERAAQVMG------PPDRCQ-----HAAHIISELILT--------AQERDGFGGLAA 335
P R +M P DR A I T A E G G
Sbjct: 312 PPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDY 371
Query: 336 ARGRGRGRGDWSVGAPGG-VQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNP 394
+ GRG S G GG + T+P D G +IGKGG+ IK I +SGA +++
Sbjct: 372 SYAGGRG----SYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPL 427
Query: 395 PPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425
+ D R TI G QI+ A+ L+ V
Sbjct: 428 EGSED---RIITITGTQDQIQNAQYLLQNSV 455
Score = 47.0 bits (110), Expect = 5e-05
Identities = 23/84 (27%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 151 GPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADK 210
G G + D+ ++ IP G +IG+GG+ IKQ++ +G + + D PL D+
Sbjct: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDR 433
Query: 211 PLRITGDAFKVQQAREMVLEIIRE 234
+ ITG ++Q A+ ++ +++
Sbjct: 434 IITITGTQDQIQNAQYLLQNSVKQ 457
Score = 35.4 bits (80), Expect = 0.14
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 356 EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQI- 414
E+ + + G VIGKGG+NIK++ A V + P +S P R +I + I
Sbjct: 44 ELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV----PDSSGPE-RILSISADIETIG 98
Query: 415 EVARQLIDEKVGGTNLGAPGAFGQSP 440
E+ +++I G L +P A Q P
Sbjct: 99 EILKKIIPTLEEGLQLPSPTATSQLP 124
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 63.2 bits (152), Expect = 6e-10
Identities = 108/451 (23%), Positives = 166/451 (36%), Gaps = 98/451 (21%)
Query: 57 KRPLDDGVGNQLGALVHQRTVITE-EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIAS 115
KRP +D Q + E + K G +IG+GG+ I ++ + + +
Sbjct: 21 KRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP- 79
Query: 116 ESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNG-----PGFHNDIDSNSTIQE---- 166
+SSG PER ++ E+I + +L +I+ G P + + S E
Sbjct: 80 DSSG-PERILSISADIETIGE---ILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNY 135
Query: 167 -------------ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLR 213
+LI S G +IG G IK+L+E T + + Q+ P D+ +
Sbjct: 136 QHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC-CPHSTDRVVL 194
Query: 214 ITGDAFKVQQAREMVLEIIREK---------------DQADFRGVRGDFNSRMGGGSIEV 258
I G +V + +++L++I E + D+ G F+ R G V
Sbjct: 195 IGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGR---PV 251
Query: 259 SVPRFAVG----IVIGRNGEMIKKIQND--------------------AGVRIQFKPDDG 294
P G + GR G + + D G R + P
Sbjct: 252 GFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPP 311
Query: 295 ISPERAAQVMG------PPDRCQ-----HAAHIISELILT--------AQERDGFGGLAA 335
P R +M P DR A I T A E G G
Sbjct: 312 PPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDY 371
Query: 336 ARGRGRGRGDWSVGAPGG-VQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNP 394
+ GRG S G GG + T+P D G +IGKGG+ IK I +SGA +++
Sbjct: 372 SYAGGRG----SYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPL 427
Query: 395 PPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425
+ D R TI G QI+ A+ L+ V
Sbjct: 428 EGSED---RIITITGTQDQIQNAQYLLQNSV 455
Score = 55.1 bits (131), Expect = 2e-07
Identities = 28/78 (35%), Positives = 45/78 (57%)
Query: 77 VITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQ 136
+IT + +P + G IIG+GG++I +I+ ESG I+I G +R +TGT + I+
Sbjct: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQN 446
Query: 137 AKRLLGQIVDRCRNGPGF 154
A+ LL V + + GF
Sbjct: 447 AQYLLQNSVKQYADVEGF 464
Score = 47.8 bits (112), Expect = 3e-05
Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 151 GPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADK 210
G G + D+ ++ IP G +IG+GG+ IKQ++ +G + + D PL D+
Sbjct: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDR 433
Query: 211 PLRITGDAFKVQQAREMVLEIIREKDQADFRG 242
+ ITG ++Q A+ ++ + K AD G
Sbjct: 434 IITITGTQDQIQNAQYLLQNSV--KQYADVEG 463
Score = 46.2 bits (108), Expect = 8e-05
Identities = 27/94 (28%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 240 FRGVRGDFNSRMGGGSI--EVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGIS 296
+ G RG + +GG I +V++P+ G +IG+ G+ IK+I++++G I+ +P +G S
Sbjct: 373 YAGGRGSYGD-LGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG-S 430
Query: 297 PERAAQVMGPPDRCQHAAHIISELILTAQERDGF 330
+R + G D+ Q+A +++ + + +GF
Sbjct: 431 EDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF 464
Score = 35.4 bits (80), Expect = 0.14
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 356 EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQI- 414
E+ + + G VIGKGG+NIK++ A V + P +S P R +I + I
Sbjct: 44 ELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV----PDSSGPE-RILSISADIETIG 98
Query: 415 EVARQLIDEKVGGTNLGAPGAFGQSP 440
E+ +++I G L +P A Q P
Sbjct: 99 EILKKIIPTLEEGLQLPSPTATSQLP 124
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 61.2 bits (147), Expect = 2e-09
Identities = 60/258 (23%), Positives = 98/258 (37%), Gaps = 32/258 (12%)
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312
++V +P +A G +IG+ G+ I ++Q + G I+ P ER + G +
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 313 AAHIISELIL------------------TAQERDGFGGLAAARGRGRGRGDWSVGAPGGV 354
I+E I T D +
Sbjct: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
Query: 355 QEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQI 414
++ VP GL+IGKGG +K++ +QSGA V+L + P + R T+ G P+Q
Sbjct: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK-PDGINLQERVVTVSGEPEQN 230
Query: 415 EVARQLIDEKV-------GGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAK 467
A +LI +K+ N+ G S P P+ NT + AA
Sbjct: 231 RKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAA---AAAG 287
Query: 468 VNGNPHSTPVSGPPAFLT 485
+ G+ + V+ PA L+
Sbjct: 288 LLGHANLAGVAAFPAVLS 305
Score = 60.8 bits (146), Expect = 3e-09
Identities = 45/195 (23%), Positives = 88/195 (45%), Gaps = 43/195 (22%)
Query: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESS---GIPERPCVLTGTPESIEQAKRL 140
+P G IIG+GG+ I ++Q E+G I+++ G ER C++ GT E++
Sbjct: 56 IPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVH-- 113
Query: 141 LGQIVDRCRNGPGFHNDIDSNSTIQ----------------------------------- 165
G I ++ R P + S +Q
Sbjct: 114 -GFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRAN 172
Query: 166 --EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQ 223
+I++P S GL+IG+GG T+K + E++G + + Q ++ + ++G+ + ++
Sbjct: 173 QVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRK 232
Query: 224 AREMVLEIIREKDQA 238
A E++++ I+E Q+
Sbjct: 233 AVELIIQKIQEDPQS 247
Score = 57.0 bits (136), Expect = 5e-08
Identities = 44/189 (23%), Positives = 75/189 (39%), Gaps = 33/189 (17%)
Query: 166 EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL-PTGADKPLRITGDAFKVQQA 224
++LIP+ G +IG+GG+TI QLQ+ TG + + + P ++ I G +
Sbjct: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
Query: 225 REMVLEIIREKDQ------------------------------ADFRGVRGDFNSRMGGG 254
+ E IRE Q + D +
Sbjct: 113 HGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRAN 172
Query: 255 SIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF--KPDDGISPERAAQVMGPPDRCQH 312
+++ VP G++IG+ G +K + +G +Q KPD ER V G P++ +
Sbjct: 173 QVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRK 232
Query: 313 AAHIISELI 321
A +I + I
Sbjct: 233 AVELIIQKI 241
Score = 47.0 bits (110), Expect = 5e-05
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%)
Query: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIP---ERPCVLTGTPESIEQA 137
E VP+ +VG I+G+GG+ + Q +G +IQI+ + +P R +TGTP + + A
Sbjct: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 484
Query: 138 KRLLGQ 143
+ L+ Q
Sbjct: 485 QYLITQ 490
Score = 46.2 bits (108), Expect = 8e-05
Identities = 23/81 (28%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 153 GFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGP-LPTGADKP 211
G D + + EI +P + VG ++G+GG+T+ + QE TG ++ + + G +P ++
Sbjct: 412 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 471
Query: 212 LRITGDAFKVQQAREMVLEII 232
+ ITG Q A+ ++ + I
Sbjct: 472 VTITGTPAATQAAQYLITQRI 492
Score = 40.0 bits (92), Expect = 0.006
Identities = 18/74 (24%), Positives = 36/74 (48%)
Query: 352 GGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVP 411
G + VP + G ++GKGG+ + + +GA +++ + R+ TI G P
Sbjct: 419 GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTP 478
Query: 412 QQIEVARQLIDEKV 425
+ A+ LI +++
Sbjct: 479 AATQAAQYLITQRI 492
Score = 38.1 bits (87), Expect = 0.022
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312
+E++VP VG ++G+ G+ + + Q G RIQ P R + G P Q
Sbjct: 424 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 483
Query: 313 AAHIISELILTAQ 325
A ++I++ I Q
Sbjct: 484 AQYLITQRITYEQ 496
>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 56.6 bits (135), Expect = 6e-08
Identities = 53/230 (23%), Positives = 96/230 (41%), Gaps = 31/230 (13%)
Query: 92 IIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNG 151
IIG+GG I +I+ ES KI + +E+S ++TG + E A+ + I
Sbjct: 596 IIGKGGANIKKIREESNTKIDLPAENSN--SETIIITGKRANCEAARSRILSI------- 646
Query: 152 PGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKP 211
D+ +N E+ IPA +IG G I+ + E G + P+
Sbjct: 647 ---QKDL-ANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHF---PVEGSGSDT 699
Query: 212 LRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGR 271
+ I G + V++A++ +L + EK F ++++ +IG+
Sbjct: 700 VVIRGPSSDVEKAKKQLLHLAEEKQTKSF--------------TVDIRAKPEYHKFLIGK 745
Query: 272 NGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELI 321
G I+K+++ G R+ F P + ++G D + A + LI
Sbjct: 746 GGGKIRKVRDSTGARVIF-PAAEDKDQDLITIIGKEDAVREAQKELEALI 794
Score = 55.8 bits (133), Expect = 1e-07
Identities = 69/343 (20%), Positives = 127/343 (37%), Gaps = 72/343 (20%)
Query: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQ 143
+P + F+IG+ GE++ ++ ++ KIQI P +TGT E IE+A+ +
Sbjct: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD--PSNQIKITGTKEGIEKARHEVLL 214
Query: 144 IVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGP 203
I ++ + + + + G + ++ + TG ++ + P
Sbjct: 215 ISAE-----------QDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINI----P 259
Query: 204 LPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRF 263
P+ + TG+ ++ QA + +I EK + +I V V +
Sbjct: 260 PPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTT--------------TIAVEVKKS 305
Query: 264 AVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILT 323
VIG G +++I GV ++ P D IS + G P++ A
Sbjct: 306 QHKYVIGPKGNSLQEILERTGVSVEIPPSDSIS--ETVILRGEPEKLGQA---------- 353
Query: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
L + SV AP + +IGK G+N+ I QQ
Sbjct: 354 ---------LTEVYAKANSFTVSSVAAPSWLHRF-----------IIGKKGQNLAKITQQ 393
Query: 384 -SGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425
H+E + T+ G + + VA++ I+ V
Sbjct: 394 MPKVHIEFTEGED--------KITLEGPTEDVNVAQEQIEGMV 428
Score = 51.6 bits (122), Expect = 2e-06
Identities = 86/406 (21%), Positives = 142/406 (34%), Gaps = 117/406 (28%)
Query: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRL 140
E + K +IG+ G I+RI+ + ++I +S + G P+ ++QAKR
Sbjct: 439 EINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSE--KSNLIRIEGDPQGVQQAKRE 496
Query: 141 LGQIVDRCRN--------GPGFHNDI---------DSNSTIQEILI----PASKVGLV-- 177
L ++ R N FH I + E++I PA K +V
Sbjct: 497 LLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQL 556
Query: 178 ----------------------------------------IGRGGETIKQLQERTGVKMV 197
IG+GG IK+++E + K+
Sbjct: 557 RGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKI- 615
Query: 198 MIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIE 257
D P + + ITG + AR +L I +KD A+ +E
Sbjct: 616 ---DLPAENSNSETIIITGKRANCEAARSRILSI--QKDLANI-------------AEVE 657
Query: 258 VSVPRFAVGIVIGRNGEMIKKIQND-AGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHI 316
VS+P +IG G +I+ I + GV I F P +G S + GP + A
Sbjct: 658 VSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHF-PVEG-SGSDTVVIRGPSSDVEKAK-- 713
Query: 317 ISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGEN 376
+L+ A+E+ R + + +IGKGG
Sbjct: 714 -KQLLHLAEEKQTKSFTVDIRAK-----------------------PEYHKFLIGKGGGK 749
Query: 377 IKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLID 422
I+ + +GA V P D + TI G + A++ ++
Sbjct: 750 IRKVRDSTGARVIF----PAAEDKDQDLITIIGKEDAVREAQKELE 791
Score = 48.5 bits (114), Expect = 2e-05
Identities = 55/244 (22%), Positives = 99/244 (40%), Gaps = 27/244 (11%)
Query: 78 ITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQA 137
+T E +VP + ++IG+ G I ++ E I + + + +TG ++++A
Sbjct: 973 VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPE--LQSDIIAITGLAANLDRA 1030
Query: 138 KRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQ--LQERTGVK 195
K +++R + D S + + +IGR G I Q L+ ++
Sbjct: 1031 K---AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQ 1087
Query: 196 MVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGS 255
DG P + ITG + AR+ +L I+ E +Q S
Sbjct: 1088 FPDKDDGNQP---QDQITITGYEKNTEAARDAILRIVGELEQMV---------------S 1129
Query: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAA- 314
+V + +IG G+ I+KI ++ V I+F P G V G P+ + A
Sbjct: 1130 EDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRF-PQSGAPDPNCVTVTGLPENVEEAID 1188
Query: 315 HIIS 318
HI++
Sbjct: 1189 HILN 1192
Score = 43.1 bits (100), Expect = 7e-04
Identities = 67/299 (22%), Positives = 118/299 (39%), Gaps = 71/299 (23%)
Query: 126 VLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETI 185
+++G E E AK L +V E+ +P VIG+ G I
Sbjct: 952 IISGRKEKCEAAKEALEALVP----------------VTIEVEVPFDLHRYVIGQKGSGI 995
Query: 186 KQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIRE-KDQADFRGVR 244
+++ + V + + P P + ITG A + +A+ +LE ++E + + + R +R
Sbjct: 996 RKMMDEFEVNIHV----PAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALR 1051
Query: 245 GDFNSRMGGGSIEVSV---PRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGISPERA 300
S ++SV P++ I IGR G +I +I+ + V IQF DDG P+
Sbjct: 1052 ----------SFKLSVTVDPKYHPKI-IGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQ 1100
Query: 301 AQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYT 360
+ G + A I ++ + Q ++
Sbjct: 1101 ITITGYEKNTEAARDAILRIVGELE-----------------------------QMVSED 1131
Query: 361 VPADK--CGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVA 417
VP D +IG G+ I+ I + + ++ P DPN T+ G+P+ +E A
Sbjct: 1132 VPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAP--DPNC--VTVTGLPENVEEA 1186
Score = 41.6 bits (96), Expect = 0.002
Identities = 58/293 (19%), Positives = 117/293 (39%), Gaps = 56/293 (19%)
Query: 74 QRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPES 133
Q T + + + F+IG+GG +I +++ +G ++ I + + + G ++
Sbjct: 724 QTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARV-IFPAAEDKDQDLITIIGKEDA 782
Query: 134 IEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTG 193
+ +A++ L ++ N +L+ + R G+ ++++ E G
Sbjct: 783 VREAQKELEALIQNL-----------DNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYG 831
Query: 194 VKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGG 253
VM+ T +DK + + G V+ A++ + EII D +++
Sbjct: 832 --GVMVSFPRSGTQSDK-VTLKGAKDCVEAAKKRIQEIIE------------DLEAQV-- 874
Query: 254 GSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA 313
++E ++P+ V+G G I++I D V+I+F PDR ++A
Sbjct: 875 -TLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKF-----------------PDREENA 916
Query: 314 AHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKC 366
H ++ QE G GR D G+P I + +KC
Sbjct: 917 VHSTEPVV---QEN------GDEAGEGREAKDCDPGSPRRCDIIIISGRKEKC 960
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/249 (21%), Positives = 94/249 (37%), Gaps = 54/249 (21%)
Query: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
+ IP VIG+ GE ++ L+ +T K+ + P P ++ITG +++AR
Sbjct: 155 VAIPKEHHRFVIGKNGEKLQDLELKTATKIQI----PRPDDPSNQIKITGTKEGIEKARH 210
Query: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
VL I E+D+ R V + V + + G ++ +I + G R
Sbjct: 211 EVLLISAEQDK---RAVE------------RLEVEKAFHPFIAGPYNRLVGEIMQETGTR 255
Query: 287 IQFKPDDGISPERAAQVM-GPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGD 345
I P S R V G ++ A I ++ +++
Sbjct: 256 INIPPP---SVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKK------------------ 294
Query: 346 WSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRF 405
I V + VIG G +++ I +++G VE+ P SD
Sbjct: 295 --------TTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEI-----PPSDSISETV 341
Query: 406 TIRGVPQQI 414
+RG P+++
Sbjct: 342 ILRGEPEKL 350
Score = 38.1 bits (87), Expect = 0.022
Identities = 43/230 (18%), Positives = 91/230 (39%), Gaps = 38/230 (16%)
Query: 91 FIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRN 150
++IG G + I +G ++I S +L G PE + QA L ++ +
Sbjct: 309 YVIGPKGNSLQEILERTGVSVEIPPSDS--ISETVILRGEPEKLGQA---LTEVYAKA-- 361
Query: 151 GPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADK 210
++ T+ + P+ +IG+ G+ + ++ ++ + +G +
Sbjct: 362 ---------NSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEG------ED 406
Query: 211 PLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIG 270
+ + G V A+E + G+ D +RM +E+++ +IG
Sbjct: 407 KITLEGPTEDVNVAQEQI------------EGMVKDLINRMD--YVEINIDHKFHRHLIG 452
Query: 271 RNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISEL 320
++G I +I++ V ++ PD ++ G P Q A + EL
Sbjct: 453 KSGANINRIKDQYKVSVRIPPDS--EKSNLIRIEGDPQGVQQAKRELLEL 500
Score = 37.7 bits (86), Expect = 0.029
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 8/143 (5%)
Query: 188 LQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDF 247
L+ER M +G + ++ TG ++ A++ L I+ R D
Sbjct: 84 LEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDI 143
Query: 248 NSRMGG-GSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGISPERAAQVMG 305
+R+ S V++P+ VIG+NGE ++ ++ +IQ +PDD P ++ G
Sbjct: 144 VARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD---PSNQIKITG 200
Query: 306 PPDRCQHAAHIISELILTAQERD 328
+ + A H E++L + E+D
Sbjct: 201 TKEGIEKARH---EVLLISAEQD 220
Score = 30.4 bits (67), Expect = 4.6
Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
Query: 358 TYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVA 417
T +P + VIGK GE ++ + ++ +++ R P++ + I G + IE A
Sbjct: 154 TVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSN-----QIKITGTKEGIEKA 208
Query: 418 R 418
R
Sbjct: 209 R 209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,569,695
Number of Sequences: 37866
Number of extensions: 1354254
Number of successful extensions: 4966
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 118
Number of HSP's that attempted gapping in prelim test: 4221
Number of HSP's gapped (non-prelim): 626
length of query: 572
length of database: 18,247,518
effective HSP length: 108
effective length of query: 464
effective length of database: 14,157,990
effective search space: 6569307360
effective search space used: 6569307360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.