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Search of human proteins with 18491000
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18491000 WNT1 inducible signaling pathway protein 1 isoform
2 precursor [Homo sapiens]
(280 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18491000 WNT1 inducible signaling pathway protein 1 isoform 2... 616 e-177
gi|4507921 WNT1 inducible signaling pathway protein 1 isoform 1 ... 361 e-100
gi|4503123 connective tissue growth factor [Homo sapiens] 165 4e-41
gi|38202241 WNT1 inducible signaling pathway protein 3 isoform 3... 161 7e-40
gi|4507925 WNT1 inducible signaling pathway protein 3 isoform 1 ... 161 7e-40
gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens] 150 2e-36
gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens] 144 1e-34
gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ... 82 4e-16
gi|134031945 SCO-spondin [Homo sapiens] 46 3e-05
gi|239755778 PREDICTED: mucin 19, oligomeric [Homo sapiens] 45 5e-05
gi|239750280 PREDICTED: mucin 19, oligomeric [Homo sapiens] 45 5e-05
gi|239744589 PREDICTED: mucin 19 [Homo sapiens] 45 5e-05
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 42 6e-04
gi|4504615 insulin-like growth factor binding protein 1 precurso... 41 0.001
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 40 0.002
gi|40317628 thrombospondin 2 precursor [Homo sapiens] 40 0.002
gi|51558724 ADAM metallopeptidase with thrombospondin type 1 mot... 40 0.003
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 40 0.003
gi|4759146 slit homolog 2 [Homo sapiens] 39 0.004
gi|4507483 thrombomodulin precursor [Homo sapiens] 38 0.009
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 38 0.011
gi|226442878 ADAMTS-like 5 [Homo sapiens] 37 0.015
gi|38683827 ADAM metallopeptidase with thrombospondin type 1 mot... 37 0.015
gi|33624896 ADAM metallopeptidase with thrombospondin type 1 mot... 37 0.019
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] 37 0.025
gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo s... 37 0.025
gi|223718260 ADAMTS-like 2 precursor [Homo sapiens] 36 0.033
gi|41281450 ADAMTS-like 2 precursor [Homo sapiens] 36 0.033
gi|169174934 PREDICTED: similar to ADAMTS-like 2 [Homo sapiens] 36 0.033
gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens] 36 0.043
>gi|18491000 WNT1 inducible signaling pathway protein 1 isoform 2
precursor [Homo sapiens]
Length = 280
Score = 616 bits (1588), Expect = e-177
Identities = 280/280 (100%), Positives = 280/280 (100%)
Query: 1 MRWFLPWTLAAVTAAAASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPP 60
MRWFLPWTLAAVTAAAASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPP
Sbjct: 1 MRWFLPWTLAAVTAAAASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPP 60
Query: 61 RCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAHAVG 120
RCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAHAVG
Sbjct: 61 RCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAHAVG 120
Query: 121 EVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLI 180
EVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLI
Sbjct: 121 EVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLI 180
Query: 181 KAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDG 240
KAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDG
Sbjct: 181 KAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDG 240
Query: 241 LGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN 280
LGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN
Sbjct: 241 LGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN 280
>gi|4507921 WNT1 inducible signaling pathway protein 1 isoform 1
precursor [Homo sapiens]
Length = 367
Score = 361 bits (926), Expect = e-100
Identities = 177/236 (75%), Positives = 184/236 (77%), Gaps = 12/236 (5%)
Query: 49 CKWPCECPPSPPRC-PLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYSGDR 107
CK+ C C C PL + + C + +C E +C+ R
Sbjct: 140 CKYNCTCIDGAVGCTPLCLRVRPPRLWCPHPRRVSIPGHCCEQWVCED--------DAKR 191
Query: 108 PRYAIGV---CAHAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQES 164
PR AVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQES
Sbjct: 192 PRKTAPRDTGAFDAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQES 251
Query: 165 RLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCI 224
RLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCI
Sbjct: 252 RLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCI 311
Query: 225 PYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN 280
PYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN
Sbjct: 312 PYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN 367
Score = 263 bits (672), Expect = 1e-70
Identities = 118/120 (98%), Positives = 118/120 (98%)
Query: 1 MRWFLPWTLAAVTAAAASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPP 60
MRWFLPWTLAAVTAAAASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPP
Sbjct: 1 MRWFLPWTLAAVTAAAASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPP 60
Query: 61 RCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAHAVG 120
RCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCA VG
Sbjct: 61 RCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAQVVG 120
>gi|4503123 connective tissue growth factor [Homo sapiens]
Length = 349
Score = 165 bits (418), Expect = 4e-41
Identities = 83/226 (36%), Positives = 122/226 (53%), Gaps = 11/226 (4%)
Query: 49 CKWPCECPPSP----PRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYS 104
CK+ C C P C + V L + C + +L C E +CD + D +
Sbjct: 120 CKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRV--KLPGKCCEEWVCDEPK----DQT 173
Query: 105 GDRPRYAIGVCAHAVGEVEAWHR-NCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQE 163
P A G R NC+ T+ WS CS +CG+G+STR++N NA C E++
Sbjct: 174 VVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQ 233
Query: 164 SRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCC 223
SRLC +RPC+ D+ IK GKKC+ + + F L+GC S ++Y+ K+CGVC D RCC
Sbjct: 234 SRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCC 293
Query: 224 IPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADL 269
P+++ T+ V F+CPDG + +++I C C+ +C NDIF L
Sbjct: 294 TPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESL 339
Score = 97.8 bits (242), Expect = 9e-21
Identities = 50/97 (51%), Positives = 59/97 (60%), Gaps = 7/97 (7%)
Query: 23 TALSPAPTTMDFTPAPLEDTSSRP---QFCKWPCECPPSP-PRCPLGVSLITDGCECCKM 78
TA S P + F L SRP Q C PC CP P PRCP GVSL+ DGC CC++
Sbjct: 2 TAASMGPVRVAFVV--LLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRV 59
Query: 79 CAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVC 115
CA+QLG+ CTE CDPH+GL+CD+ G IGVC
Sbjct: 60 CAKQLGELCTERDPCDPHKGLFCDF-GSPANRKIGVC 95
>gi|38202241 WNT1 inducible signaling pathway protein 3 isoform 3
[Homo sapiens]
Length = 372
Score = 161 bits (407), Expect = 7e-40
Identities = 65/148 (43%), Positives = 96/148 (64%), Gaps = 2/148 (1%)
Query: 125 WHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKA-- 182
W + C+ + W+PCS +CG+G+S R++N N+ C +E RLC ++PCD +I IK
Sbjct: 223 WKKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPK 282
Query: 183 GKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLG 242
GK C +Q + F +GC ST+SY+P +CG+C+D RCCIP KSK I + F CP+
Sbjct: 283 GKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGS 342
Query: 243 FSRQVLWINACFCNLSCRNPNDIFADLE 270
F ++LWI +C C +CR P DIF++L+
Sbjct: 343 FKWKMLWITSCVCQRNCREPGDIFSELK 370
Score = 136 bits (343), Expect = 2e-32
Identities = 56/93 (60%), Positives = 66/93 (70%)
Query: 27 PAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCAQQLGDN 86
P TT + P + D R QFC WPC+CP PRCP GVSL+ DGC CCK+CA+Q G+
Sbjct: 44 PLDTTPEGRPGEVSDAPQRKQFCHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEI 103
Query: 87 CTEAAICDPHRGLYCDYSGDRPRYAIGVCAHAV 119
C EA +CDPH+GLYCDYS DRPRY GVCA+ V
Sbjct: 104 CNEADLCDPHKGLYCDYSVDRPRYETGVCAYLV 136
>gi|4507925 WNT1 inducible signaling pathway protein 3 isoform 1
[Homo sapiens]
Length = 354
Score = 161 bits (407), Expect = 7e-40
Identities = 65/148 (43%), Positives = 96/148 (64%), Gaps = 2/148 (1%)
Query: 125 WHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKA-- 182
W + C+ + W+PCS +CG+G+S R++N N+ C +E RLC ++PCD +I IK
Sbjct: 205 WKKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPK 264
Query: 183 GKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLG 242
GK C +Q + F +GC ST+SY+P +CG+C+D RCCIP KSK I + F CP+
Sbjct: 265 GKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGS 324
Query: 243 FSRQVLWINACFCNLSCRNPNDIFADLE 270
F ++LWI +C C +CR P DIF++L+
Sbjct: 325 FKWKMLWITSCVCQRNCREPGDIFSELK 352
Score = 136 bits (343), Expect = 2e-32
Identities = 56/93 (60%), Positives = 66/93 (70%)
Query: 27 PAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCAQQLGDN 86
P TT + P + D R QFC WPC+CP PRCP GVSL+ DGC CCK+CA+Q G+
Sbjct: 26 PLDTTPEGRPGEVSDAPQRKQFCHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEI 85
Query: 87 CTEAAICDPHRGLYCDYSGDRPRYAIGVCAHAV 119
C EA +CDPH+GLYCDYS DRPRY GVCA+ V
Sbjct: 86 CNEADLCDPHKGLYCDYSVDRPRYETGVCAYLV 118
>gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
Length = 381
Score = 150 bits (378), Expect = 2e-36
Identities = 62/155 (40%), Positives = 97/155 (62%), Gaps = 7/155 (4%)
Query: 127 RNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKC 186
+ CI T+ WS CS +CG G+STR++N N +C +E+R+C +RPC +++ +K GKKC
Sbjct: 227 QKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKC 286
Query: 187 LAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQ 246
+ + FT AGC+S + Y+PKYCG C+D RCC P ++T+ + F+C DG FS+
Sbjct: 287 SKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKN 346
Query: 247 VLWINACFCNLSCRNPND-------IFADLESYPD 274
V+ I +C CN +C + N+ +F D+ + D
Sbjct: 347 VMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD 381
Score = 69.3 bits (168), Expect = 3e-12
Identities = 35/98 (35%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 18 STVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCK 77
S+ +A AL+ T + T L C C CP P+C GV L+ DGC CCK
Sbjct: 2 SSRIARALALVVTLLHLTRLALST-------CPAACHCPLEAPKCAPGVGLVRDGCGCCK 54
Query: 78 MCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVC 115
+CA+QL ++C++ CD +GL C++ G G+C
Sbjct: 55 VCAKQLNEDCSKTQPCDHTKGLECNF-GASSTALKGIC 91
>gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]
Length = 357
Score = 144 bits (362), Expect = 1e-34
Identities = 81/228 (35%), Positives = 113/228 (49%), Gaps = 20/228 (8%)
Query: 49 CKWPCECPPSP----PRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHR-----GL 99
CK+ C C PRC L V L C + ++ C E IC P GL
Sbjct: 127 CKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKV--EVPGECCEKWICGPDEEDSLGGL 184
Query: 100 YCDYSGDRPRYAIGVCAHAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCW 159
+ RP +GV EV NCI T+ W+ CS SCG+G STR++N N QC
Sbjct: 185 --TLAAYRPEATLGV------EVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCE 236
Query: 160 PEQESRLCNLRPCDVDIHTLI-KAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCM 218
+++RLC +RPC+ + K GKKCL + +++ C S +Y+P++CGVC
Sbjct: 237 MLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCS 296
Query: 219 DNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIF 266
D RCC P+ +KTI FQC G + V+ I C C+ +C N+ F
Sbjct: 297 DGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAF 344
Score = 77.0 bits (188), Expect = 2e-14
Identities = 53/165 (32%), Positives = 69/165 (41%), Gaps = 29/165 (17%)
Query: 52 PCECPPSPPRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYA 111
P CP +PP C GV + DGC CC +CA+Q G++C++ CD GLYCD S D P
Sbjct: 40 PGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSAD-PSNQ 98
Query: 112 IGVCAHAVGEVEAWHRNC----IAYTS--PWSP--------------CSTSCGLGVSTRI 151
G+C G+ NC + Y S + P C C L V
Sbjct: 99 TGICTAVEGD------NCVFDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPE 152
Query: 152 SNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASM 196
N A E C C D + G LA Y+PEA++
Sbjct: 153 PNCPAPRKVEVPGECCEKWICGPDEEDSL--GGLTLAAYRPEATL 195
>gi|4507923 WNT1 inducible signaling pathway protein 2 precursor
[Homo sapiens]
Length = 250
Score = 82.4 bits (202), Expect = 4e-16
Identities = 31/57 (54%), Positives = 40/57 (70%)
Query: 45 RPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYC 101
R Q C PC CP PPRCPLGV L+ DGC CC++CA++LG+ C + +CD +GL C
Sbjct: 22 RTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVC 78
Score = 57.4 bits (137), Expect = 1e-08
Identities = 23/44 (52%), Positives = 31/44 (70%)
Query: 129 CIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPC 172
C +++ W PCST+CGLG++TR+SN N C E + RLC RPC
Sbjct: 194 CPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPC 237
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 46.2 bits (108), Expect = 3e-05
Identities = 62/280 (22%), Positives = 94/280 (33%), Gaps = 47/280 (16%)
Query: 2 RWFLPWTLAAVTAAAASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPR 61
RW PW+ + ++ + + S P+ P E +R C P
Sbjct: 4009 RWS-PWSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARL------CNPMPCEAG 4061
Query: 62 CPLGVSLITDGCECCKMCAQ-QLGDNCTEAAICD-----PHRGL----------YCDYS- 104
CP G+ ++T C + C+ Q G C + +C P L +CD +
Sbjct: 4062 CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTD 4121
Query: 105 --------GDRPRYAIGVCAHAVGEVEAWHRNCIAYT-------SPWSPCSTSCG-LGVS 148
G + + A C+ G++ + C T S WSPCS SCG G
Sbjct: 4122 AQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQ 4181
Query: 149 TRISNVNAQCW-PEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTR 207
+R + + W PE +PC CL + + L G
Sbjct: 4182 SRFRSSTSGSWAPECREEQSQSQPCPQP-----SCPPLCLQGTRSRTLGDSWLQGECQRC 4236
Query: 208 SYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQV 247
S P+ +C D C +P CP G QV
Sbjct: 4237 SCTPEGV-ICEDTECAVPEAWTLWSSWSDCPVSCGGGNQV 4275
Score = 40.8 bits (94), Expect = 0.001
Identities = 38/170 (22%), Positives = 61/170 (35%), Gaps = 43/170 (25%)
Query: 134 SPWSPCSTSCGLGVSTR------ISNVNAQC-WPEQESRLCNLRPCDVDI--HTLIKAGK 184
+PWS CS C G+ TR ++ + C P ++R CN +PC + L ++ +
Sbjct: 2837 APWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAE 2896
Query: 185 KCLAVYQPEASMNFTLAGCISTRSYQPKYC----GVCMDNRCCIP--------------- 225
+C P + T I + C G+ + N C+P
Sbjct: 2897 QCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYAS 2956
Query: 226 --------------YKSKTIDVSFQCPDGLGFSRQVLW-INACFCNLSCR 260
K S +CP G+S LW + +C CN+ R
Sbjct: 2957 GAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIR 3006
Score = 38.5 bits (88), Expect = 0.007
Identities = 48/188 (25%), Positives = 64/188 (34%), Gaps = 44/188 (23%)
Query: 23 TALSPAPTTMDFTPAPLEDTSSRPQFCKWPC----------ECPPSPPRCPLGVSLITDG 72
++L+P TT + D +++P C C +C CP G
Sbjct: 2858 SSLAPGDTTCPGPHSQTRDCNTQP--CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
Query: 73 CECCKMCAQQLGDNCTEA-----AICDPHRGLYCDYSGDRPRYAIGV---------CAHA 118
EC CA G C A C P C G YA G C
Sbjct: 2916 IECTGFCAP--GCTCPPGLFLHNASCLPRSQCPCQLHGQL--YASGAMARLDSCNNCTCV 2971
Query: 119 VGEVEAWHRNCIAYT--SPW---SPCSTSCGLGVSTRI--------SNVNAQC-WPEQES 164
G++ C SPW S CS SC +G+ R + A+C P E+
Sbjct: 2972 SGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEA 3031
Query: 165 RLCNLRPC 172
C+LRPC
Sbjct: 3032 EFCSLRPC 3039
Score = 37.7 bits (86), Expect = 0.011
Identities = 24/59 (40%), Positives = 28/59 (47%), Gaps = 13/59 (22%)
Query: 128 NCIAYTS--PWSPCSTSCGLGVSTRI-----SNVNAQCWPE-----QESRLCNLRPCDV 174
NC ++TS PW PCS SCG+G R+ P QE R CNLR C V
Sbjct: 3946 NC-SWTSWAPWEPCSRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPV 4003
Score = 36.6 bits (83), Expect = 0.025
Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 135 PWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEA 194
PWSPCS CG G R + E C L+PC + + K+ L Q A
Sbjct: 3048 PWSPCSVPCGGGYRNRTRGSSRSL---MEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPA 3104
Query: 195 SMNFTLAGCISTRSYQPK-YC--GVCMDNRCCIP 225
S A + ++ P +C G+ + N C+P
Sbjct: 3105 SCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVP 3138
Score = 34.7 bits (78), Expect = 0.096
Identities = 36/114 (31%), Positives = 45/114 (39%), Gaps = 20/114 (17%)
Query: 49 CKWPCECPPSPPRCPLGVSLITDGCECCKMC--AQQLGDNCTEAAICDPHRGLYCDY--- 103
C+ C CP + L C C Q+LG A I DP + L
Sbjct: 3730 CEEGCHCPEGTFQHRLAC---VQECPCVLTAWLLQELG-----ATIGDPGQPLGPGDELD 3781
Query: 104 SGDRPRYAIGVCAHAVGEVEAWHRNCIAYT------SPWSPCSTSC-GLGVSTR 150
SG R + G C+ A G++ +C SPW PCS SC GLG TR
Sbjct: 3782 SGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTR 3835
Score = 32.3 bits (72), Expect = 0.47
Identities = 21/50 (42%), Positives = 24/50 (48%), Gaps = 8/50 (16%)
Query: 134 SPWSPCSTSC---GLGVSTRISN----VNAQC-WPEQESRLCNLRPCDVD 175
SPW PCS +C G G S R S V C PE +S+ C C VD
Sbjct: 1701 SPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVD 1750
Score = 32.0 bits (71), Expect = 0.62
Identities = 38/144 (26%), Positives = 48/144 (33%), Gaps = 34/144 (23%)
Query: 54 ECPPSPPRCPLGVSLIT----DGCECCKMCAQQLGDNCTEAA-----------ICDPHRG 98
EC + RC L DGC C + + +C+ + + P G
Sbjct: 2475 ECLSAERRCDLRPDCQDGSDEDGCVDCVLAPWSVWSSCSRSCGLGLTFQRQELLRPPLPG 2534
Query: 99 LYCDYSGDRPRYAIGVC-AHAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTR------- 150
C R R+ C A AW A W PCS SCG G +R
Sbjct: 2535 GSCP----RDRFRSQSCFVQACPVAGAW-----AMWEAWGPCSVSCGGGHQSRQRSCVDP 2585
Query: 151 -ISNVNAQC-WPEQESRLCNLRPC 172
N A C QE C L+PC
Sbjct: 2586 PPKNGGAPCPGASQERAPCGLQPC 2609
Score = 31.2 bits (69), Expect = 1.1
Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 9/59 (15%)
Query: 135 PWSPCSTSCGLGVSTRI--------SNVNAQC-WPEQESRLCNLRPCDVDIHTLIKAGK 184
PWS CS SCG G+ +R + C P + +C PC V T I+ +
Sbjct: 3260 PWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIEGAE 3318
Score = 31.2 bits (69), Expect = 1.1
Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 33/146 (22%)
Query: 52 PCECPPSPPRC-------PLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYS 104
PC P PP C LG S + C+ C + + TE A+ + L+ +S
Sbjct: 4205 PCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPEAWT-LWSSWS 4263
Query: 105 GDRPRYAIG---VCAHAVGEVEAWHRN--CIAYTS-----------------PWSPCSTS 142
D P G V A HR+ C+ + PW PCS S
Sbjct: 4264 -DCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPWGPCSRS 4322
Query: 143 CGLGVSTRISNVNAQCWPEQESRLCN 168
CG G+++R + + C + CN
Sbjct: 4323 CGPGLASR--SGSCPCLMAKADPTCN 4346
Score = 30.0 bits (66), Expect = 2.4
Identities = 17/56 (30%), Positives = 23/56 (41%), Gaps = 9/56 (16%)
Query: 126 HRNC--IAYTSPWSPCSTSCGLGVSTRISNVN-------AQCWPEQESRLCNLRPC 172
H+ C + S WS CS CG G R Q ++ + CNL+PC
Sbjct: 4760 HQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPC 4815
Score = 29.6 bits (65), Expect = 3.1
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 2/40 (5%)
Query: 135 PWSPCSTSCGLGVSTRISN-VNAQC-WPEQESRLCNLRPC 172
PW CS SCG G R C P ++SR C+ + C
Sbjct: 3653 PWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVC 3692
Score = 29.3 bits (64), Expect = 4.0
Identities = 15/45 (33%), Positives = 17/45 (37%), Gaps = 10/45 (22%)
Query: 135 PWSPCSTSCGLGVSTRISNVNAQC-------WPEQESRLCNLRPC 172
PWSPC C G R A C W ++ CN PC
Sbjct: 4623 PWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQES---CNGGPC 4664
Score = 28.1 bits (61), Expect = 8.9
Identities = 10/17 (58%), Positives = 11/17 (64%)
Query: 134 SPWSPCSTSCGLGVSTR 150
S W+PC SCG GV R
Sbjct: 2722 SSWAPCDRSCGSGVRAR 2738
Score = 28.1 bits (61), Expect = 8.9
Identities = 16/45 (35%), Positives = 18/45 (40%), Gaps = 6/45 (13%)
Query: 134 SPWSPCSTSC------GLGVSTRISNVNAQCWPEQESRLCNLRPC 172
S WSPCS SC TR+ N + R CNL C
Sbjct: 3887 SSWSPCSRSCTDPARPAWRSRTRLCLANCTMGDPLQERPCNLPSC 3931
>gi|239755778 PREDICTED: mucin 19, oligomeric [Homo sapiens]
Length = 598
Score = 45.4 bits (106), Expect = 5e-05
Identities = 51/225 (22%), Positives = 76/225 (33%), Gaps = 39/225 (17%)
Query: 42 TSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYC 101
T ++ CK P ECP SPP C G L+ Q D C E C+P L+
Sbjct: 399 TDAKTIDCK-PEECP-SPPTCKTGEKLVKF----------QSNDTCCEIGYCEPRTCLF- 445
Query: 102 DYSGDRPRYAIGVCAHAVGEVEAWHRNCIAYTSPWSPC-STSC-GLGVSTRISNVNAQCW 159
+ Y IG ++ P +PC S SC G + + + Q W
Sbjct: 446 ----NNTDYEIGA----------------SFDDPSNPCVSYSCKDTGFAAVVQDCPKQTW 485
Query: 160 PEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCM- 218
+ +R+ + + C ++ + V +A C KY +
Sbjct: 486 CAEANRIYDSKKCCYTCKNNCRSSLVNVTVIYSGCKKRVQMAKCTGECEKTAKYNYDILL 545
Query: 219 ---DNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCR 260
CC + D+ CPDG Q I C C C+
Sbjct: 546 LEHSCLCCREENYELRDIVLDCPDGSTIPYQYKHITTCSCLDICQ 590
>gi|239750280 PREDICTED: mucin 19, oligomeric [Homo sapiens]
Length = 598
Score = 45.4 bits (106), Expect = 5e-05
Identities = 51/225 (22%), Positives = 76/225 (33%), Gaps = 39/225 (17%)
Query: 42 TSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYC 101
T ++ CK P ECP SPP C G L+ Q D C E C+P L+
Sbjct: 399 TDAKTIDCK-PEECP-SPPTCKTGEKLVKF----------QSNDTCCEIGYCEPRTCLF- 445
Query: 102 DYSGDRPRYAIGVCAHAVGEVEAWHRNCIAYTSPWSPC-STSC-GLGVSTRISNVNAQCW 159
+ Y IG ++ P +PC S SC G + + + Q W
Sbjct: 446 ----NNTDYEIGA----------------SFDDPSNPCVSYSCKDTGFAAVVQDCPKQTW 485
Query: 160 PEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCM- 218
+ +R+ + + C ++ + V +A C KY +
Sbjct: 486 CAEANRIYDSKKCCYTCKNNCRSSLVNVTVIYSGCKKRVQMAKCTGECEKTAKYNYDILL 545
Query: 219 ---DNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCR 260
CC + D+ CPDG Q I C C C+
Sbjct: 546 LEHSCLCCREENYELRDIVLDCPDGSTIPYQYKHITTCSCLDICQ 590
>gi|239744589 PREDICTED: mucin 19 [Homo sapiens]
Length = 598
Score = 45.4 bits (106), Expect = 5e-05
Identities = 51/225 (22%), Positives = 76/225 (33%), Gaps = 39/225 (17%)
Query: 42 TSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYC 101
T ++ CK P ECP SPP C G L+ Q D C E C+P L+
Sbjct: 399 TDAKTIDCK-PEECP-SPPTCKTGEKLVKF----------QSNDTCCEIGYCEPRTCLF- 445
Query: 102 DYSGDRPRYAIGVCAHAVGEVEAWHRNCIAYTSPWSPC-STSC-GLGVSTRISNVNAQCW 159
+ Y IG ++ P +PC S SC G + + + Q W
Sbjct: 446 ----NNTDYEIGA----------------SFDDPSNPCVSYSCKDTGFAAVVQDCPKQTW 485
Query: 160 PEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCM- 218
+ +R+ + + C ++ + V +A C KY +
Sbjct: 486 CAEANRIYDSKKCCYTCKNNCRSSLVNVTVIYSGCKKRVQMAKCTGECEKTAKYNYDILL 545
Query: 219 ---DNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCR 260
CC + D+ CPDG Q I C C C+
Sbjct: 546 LEHSCLCCREENYELRDIVLDCPDGSTIPYQYKHITTCSCLDICQ 590
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 42.0 bits (97), Expect = 6e-04
Identities = 64/256 (25%), Positives = 91/256 (35%), Gaps = 57/256 (22%)
Query: 46 PQFCKWPCECPPSPPRCPLGVSLITDGCE--CCKMC---AQQLGDNCTEAAICDPHRGLY 100
P FC CPPS L+ + CE C + C GD+ +E C P + +
Sbjct: 2196 PDFCAM--SCPPS---------LVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVML 2244
Query: 101 CDYSGDRPRYAIGVCAHAVGE-------VEAW---HRNCIAYTS--------PWSPCSTS 142
P A C +GE +EAW H+ C T PC T+
Sbjct: 2245 --EGSCVPEEA---CTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTA 2299
Query: 143 ----CGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNF 198
CGL R+ QC PE E +C+ CD+ + G + E NF
Sbjct: 2300 KAPTCGLCEVARLRQNADQCCPEYEC-VCDPVSCDLPPVPHCERGLQPTLTNPGECRPNF 2358
Query: 199 TLAGC-------ISTRSYQPKYCGVCMDNRCCIPYK--SKTIDVSFQCPDGLGFSRQVLW 249
T A C +S S P +CC Y+ ++ + CP LG+
Sbjct: 2359 TCA-CRKEECKRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCP--LGYLASTA- 2414
Query: 250 INACFCNLSCRNPNDI 265
N C C + P+ +
Sbjct: 2415 TNDCGCTTTTCLPDKV 2430
Score = 29.3 bits (64), Expect = 4.0
Identities = 23/107 (21%), Positives = 39/107 (36%), Gaps = 6/107 (5%)
Query: 150 RISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSY 209
+I + C E CN DI ++ K + E +++ C S Y
Sbjct: 2707 KIMKIPGTCCDTCEEPECN------DITARLQYVKVGSCKSEVEVDIHYCQGKCASKAMY 2760
Query: 210 QPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFCN 256
V CC P +++ + V+ C +G +VL C C+
Sbjct: 2761 SIDINDVQDQCSCCSPTRTEPMQVALHCTNGSVVYHEVLNAMECKCS 2807
>gi|4504615 insulin-like growth factor binding protein 1 precursor
[Homo sapiens]
Length = 259
Score = 40.8 bits (94), Expect = 0.001
Identities = 60/230 (26%), Positives = 85/230 (36%), Gaps = 53/230 (23%)
Query: 42 TSSRPQFCKWPCE------CPPSPPRCPLGVSLITD--GCECCKMCAQQLGDNCTEA-AI 92
T+ P C PC CPP C S +T GC CC MCA LG C A A
Sbjct: 23 TAGAPWQCA-PCSAEKLALCPPVSASC----SEVTRSAGCGCCPMCALPLGAACGVATAR 77
Query: 93 CDPHRGLYCDY--SGDRPRYAI----GVCAHAVGEVEAWHRNCIAYTSPWSPCSTSCGLG 146
C RGL C +P +A+ G C V E +A + SP SP ST +
Sbjct: 78 C--ARGLSCRALPGEQQPLHALTRGQGAC---VQESDASAPHAAEAGSPESPESTE--IT 130
Query: 147 VSTRISNVNAQCWPEQES----------------RLCNLR----PCDVDIHTLIKAGKKC 186
+ N + E++ + N++ PC ++++ ++++ K
Sbjct: 131 EEELLDNFHLMAPSEEDHSILWDAISTYDGSKALHVTNIKKWKEPCRIELYRVVESLAKA 190
Query: 187 LAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNR-----CCIPYKSKTI 231
E S F L C Y + C MD C P+ K I
Sbjct: 191 QETSGEEIS-KFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRI 239
>gi|4504619 insulin-like growth factor binding protein 7 [Homo
sapiens]
Length = 282
Score = 40.4 bits (93), Expect = 0.002
Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 9/74 (12%)
Query: 52 PCECPPSPPR-CPLGVSLITDGCECCKMCAQQLGDNC----TEAAICDPHRGLYCDYSGD 106
P CPP PP C LG + D C CC MCA+ G+ C C P G+ C S
Sbjct: 37 PASCPPLPPLGCLLGET--RDACGCCPMCARGEGEPCGGGGAGRGYCAP--GMECVKSRK 92
Query: 107 RPRYAIGVCAHAVG 120
R + G A G
Sbjct: 93 RRKGKAGAAAGGPG 106
>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
Length = 1172
Score = 40.4 bits (93), Expect = 0.002
Identities = 46/191 (24%), Positives = 73/191 (38%), Gaps = 45/191 (23%)
Query: 55 CPPSPPRCPLGVSLITDGCECCKMCAQQLGDN--------CTEAAIC----DPHRGLYCD 102
CPP+ P V ECC C + T+ ++ RG CD
Sbjct: 355 CPPATCASPSFVE-----GECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCD 409
Query: 103 YSGDR---PRYAIGVCAHAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCW 159
+ + P C+ + + ++ SPWS CS +CG+G TRI N+
Sbjct: 410 VTSNTCLGPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPV- 468
Query: 160 PE----------QESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTR-- 207
P+ +E++ C PC +D G+ + + P ++ T AG I R
Sbjct: 469 PQMGGKNCKGSGRETKACQGAPCPID-------GR--WSPWSPWSACTVTCAGGIRERTR 519
Query: 208 ---SYQPKYCG 215
S +P+Y G
Sbjct: 520 VCNSPEPQYGG 530
Score = 34.7 bits (78), Expect = 0.096
Identities = 26/90 (28%), Positives = 33/90 (36%), Gaps = 23/90 (25%)
Query: 98 GLYCDYSGDRPRYAIGVCAHAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQ 157
G C SG + G G W SPWS C+ +C G+ R N+
Sbjct: 473 GKNCKGSGRETKACQGAPCPIDGRWSPW--------SPWSACTVTCAGGIRERTRVCNS- 523
Query: 158 CWPE------------QESRLCNLRPCDVD 175
PE QE ++CN R C VD
Sbjct: 524 --PEPQYGGKACVGDVQERQMCNKRSCPVD 551
>gi|51558724 ADAM metallopeptidase with thrombospondin type 1 motif,
12 preproprotein [Homo sapiens]
Length = 1594
Score = 39.7 bits (91), Expect = 0.003
Identities = 38/139 (27%), Positives = 54/139 (38%), Gaps = 33/139 (23%)
Query: 45 RPQFCKWPCECPPSPPRCPLGVSLITDGCECCKM-----CAQQLGDNCTEAAICDPHRGL 99
RP C++ PP PL +S + CE ++ C++ G E + P G
Sbjct: 1401 RPFHCQFLAGIPP-----PLSMSCNPEPCEAWQVEPWSQCSRSCGGGVQERGVFCP--GG 1453
Query: 100 YCDYSGDRPRYAIGVCAHAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCW 159
CD++ RP + H C T W CSTSCG G R QC
Sbjct: 1454 LCDWT-KRPTSTMSCNEHLC---------CHWATGNWDLCSTSCGGGFQKR----TVQCV 1499
Query: 160 P-------EQESRLCNLRP 171
P +Q+ LC+ +P
Sbjct: 1500 PSEGNKTEDQDQCLCDHKP 1518
Score = 35.0 bits (79), Expect = 0.073
Identities = 20/48 (41%), Positives = 26/48 (54%), Gaps = 9/48 (18%)
Query: 134 SPWSPCSTSCGLGVST--RISN------VNAQCWPEQES-RLCNLRPC 172
SPWS CS +CG GV + R+ N C E++ RLCN+ PC
Sbjct: 549 SPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPC 596
Score = 34.7 bits (78), Expect = 0.096
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 7/44 (15%)
Query: 136 WSPCSTSCGLGV-------STRISNVNAQCWPEQESRLCNLRPC 172
WS CST+CGLG ST++ + A ++ C+LRPC
Sbjct: 1322 WSECSTTCGLGAYWRRVECSTQMDSDCAAIQRPDPAKRCHLRPC 1365
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 39.7 bits (91), Expect = 0.003
Identities = 67/262 (25%), Positives = 85/262 (32%), Gaps = 71/262 (27%)
Query: 24 ALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCAQQL 83
A SP + TP L DT CE P CP G T G C + C
Sbjct: 500 ACSPIDGSCSCTPGWLGDT----------CELP-----CPDG----TFGLNCSEHC---- 536
Query: 84 GDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAHAVGEVEAWHRNCIAYTSPWSPCSTSC 143
+C+ A CDP G C +G G+ + W NC S SC
Sbjct: 537 --DCSHADGCDPVTGHCCCLAG-----WTGIRCDSTCPPGRWGPNC--------SVSCSC 581
Query: 144 GLGVSTRISNVNAQCWPEQESRLCN------------LRPCDVDIHTL-----IKAGKKC 186
G S + + +C P LC +PC + +H+ I +C
Sbjct: 582 ENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICEC 641
Query: 187 LAVYQPEASMNFTLAGCISTRSYQPKYC---GVC--MDNRC-CIP-YKSKTIDVSFQCPD 239
L + G Q C G C +D C C P + K D S CP
Sbjct: 642 LPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGK--DCSQACPP 699
Query: 240 GLGFSRQVLWINACFCNLSCRN 261
G W ACF SC N
Sbjct: 700 G-------FWGPACFHACSCHN 714
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 39.3 bits (90), Expect = 0.004
Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 1/56 (1%)
Query: 201 AGCISTRSYQPKYC-GVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFC 255
A C +T+ C G C +CC P +SK SF+C DG F +V + C C
Sbjct: 1469 AACQTTKKVSRLECRGGCAGGQCCGPLRSKRRKYSFECTDGSSFVDEVEKVVKCGC 1524
>gi|4507483 thrombomodulin precursor [Homo sapiens]
Length = 575
Score = 38.1 bits (87), Expect = 0.009
Identities = 48/203 (23%), Positives = 73/203 (35%), Gaps = 35/203 (17%)
Query: 49 CKWPCECPPSPPRC--PLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHR-GLY---CD 102
C+ C P PRC P G +L DG C Q D C + +P + G Y C+
Sbjct: 252 CEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCE 311
Query: 103 YSGDRPRYAIGVCAHAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQ 162
Y + H +V+ +CI SPC C V+T+ C+P
Sbjct: 312 TG-----YRLAADQHRCEDVD----DCILEP---SPCPQRC---VNTQ-GGFECHCYPNY 355
Query: 163 ESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSY-----QPKYCGVC 217
+ L + C + +A C QP +N T C+ + +P C +
Sbjct: 356 D--LVD-GECVEPVDPCFRA--NCEYQCQP---LNQTSYLCVCAEGFAPIPHEPHRCQMF 407
Query: 218 MDNRCCIPYKSKTIDVSFQCPDG 240
+ C S +CP+G
Sbjct: 408 CNQTACPADCDPNTQASCECPEG 430
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor
[Homo sapiens]
Length = 1584
Score = 37.7 bits (86), Expect = 0.011
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 6/41 (14%)
Query: 134 SPWSPCSTSCGLGVSTRI-----SNVNAQC-WPEQESRLCN 168
SPWS CS++CG G TR S+ + QC P +E RLCN
Sbjct: 361 SPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCN 401
Score = 34.7 bits (78), Expect = 0.096
Identities = 34/136 (25%), Positives = 54/136 (39%), Gaps = 23/136 (16%)
Query: 134 SPWSPCSTSCGLGVSTRISNV-------NAQCWPEQESRLCNLRPCDVDIHTLIKAGKKC 186
SPWS CS++CG G R N PE++++ CN+ C G+
Sbjct: 416 SPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALC---------PGRAV 466
Query: 187 LAVYQPEASMNFTLAGCISTRSYQPKYC-GVCMDNRCCIPYKSKTIDVSF-QCP-DGLGF 243
+ +S + A C R + + C G C + +T D QCP DG
Sbjct: 467 DGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVDG--- 523
Query: 244 SRQVLWINACFCNLSC 259
+ W + C+++C
Sbjct: 524 -KWQAWASWGSCSVTC 538
>gi|226442878 ADAMTS-like 5 [Homo sapiens]
Length = 471
Score = 37.4 bits (85), Expect = 0.015
Identities = 24/67 (35%), Positives = 28/67 (41%), Gaps = 14/67 (20%)
Query: 112 IGVCAHAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNV-----NAQCWPE-QESR 165
+GV A GE W W+ CS+SCG GVS R CW + E R
Sbjct: 28 LGVSAQGPGEWTPW--------VSWTRCSSSCGRGVSVRSRRCLRLPGEEPCWGDSHEYR 79
Query: 166 LCNLRPC 172
LC L C
Sbjct: 80 LCQLPDC 86
>gi|38683827 ADAM metallopeptidase with thrombospondin type 1 motif, 7
preproprotein [Homo sapiens]
Length = 1686
Score = 37.4 bits (85), Expect = 0.015
Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 7/53 (13%)
Query: 127 RNCIAYTSPWSPCSTSCGLGVSTR----ISNVNAQCWP---EQESRLCNLRPC 172
RN WS CST+CGLG R S + C P Q +R C+LRPC
Sbjct: 1411 RNAGWQAGNWSECSTTCGLGAVWRPVRCSSGRDEDCAPAGRPQPARRCHLRPC 1463
Score = 32.0 bits (71), Expect = 0.62
Identities = 37/145 (25%), Positives = 47/145 (32%), Gaps = 39/145 (26%)
Query: 52 PCECPPSPPRCPLGVSLITDGC---------ECCKMCA---QQLGDNCTEAAICDPHRGL 99
P C P P + P C EC + C QQ C E +C+
Sbjct: 1500 PFHCQPGPAKPPAHRPCGAQPCLSWYTSSWRECSEACGGGEQQRLVTCPEPGLCE----- 1554
Query: 100 YCDYSGDRPRYAIGVCAHAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTR-ISNVNAQC 158
RP H + W PW CS CG GV R + VN Q
Sbjct: 1555 ----EALRPNTTRPCNTHPCTQ---W------VVGPWGQCSGPCGGGVQRRLVKCVNTQT 1601
Query: 159 -WPEQESRLC-------NLRPCDVD 175
PE++S C + RPC +
Sbjct: 1602 GLPEEDSDQCGHEAWPESSRPCGTE 1626
Score = 30.4 bits (67), Expect = 1.8
Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 9/48 (18%)
Query: 134 SPWSPCSTSCGLGVSTRISNV--------NAQCWPEQES-RLCNLRPC 172
S WS CS SCG+GV + C E++ RLCNL+ C
Sbjct: 545 SAWSICSRSCGMGVQSAERQCTQPTPKYKGRYCVGERKRFRLCNLQAC 592
Score = 28.1 bits (61), Expect = 8.9
Identities = 17/68 (25%), Positives = 26/68 (38%), Gaps = 27/68 (39%)
Query: 122 VEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCW-----------------PEQES 164
V +WH PW+ C+ +CG GV + N C P+ +
Sbjct: 822 VFSWHYG------PWTKCTVTCGRGVQRQ----NVYCLERQAGPVDEEHCDPLGRPDDQQ 871
Query: 165 RLCNLRPC 172
R C+ +PC
Sbjct: 872 RKCSEQPC 879
>gi|33624896 ADAM metallopeptidase with thrombospondin type 1 motif, 9
preproprotein [Homo sapiens]
Length = 1935
Score = 37.0 bits (84), Expect = 0.019
Identities = 31/98 (31%), Positives = 36/98 (36%), Gaps = 19/98 (19%)
Query: 74 ECCKMCAQQLGDNCTEAAICDPHRG-----LYCDYSGDRPRYAIGVCAHAVGEVEAWHRN 128
EC K+C G T +C G L C+ D+P HA AW
Sbjct: 1393 ECTKLCG---GGIRTRLVVCQRSNGERFPDLSCEIL-DKPPDREQCNTHACPHDAAWS-- 1446
Query: 129 CIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRL 166
T PWS CS SCG G R N C + S L
Sbjct: 1447 ----TGPWSSCSVSCGRGHKQR----NVYCMAKDGSHL 1476
Score = 36.2 bits (82), Expect = 0.033
Identities = 28/99 (28%), Positives = 38/99 (38%), Gaps = 21/99 (21%)
Query: 60 PRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHR----GLYCDYSG---DRPRYAI 112
PRCPL + EC K C + G + D ++ G CD S DR ++
Sbjct: 1552 PRCPLYTWRAEEWQECTKTCGE--GSRYRKVVCVDDNKNEVHGARCDVSKRPVDRESCSL 1609
Query: 113 GVCAHAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRI 151
C + W T WS CS +CG G R+
Sbjct: 1610 QPCEYV------W------ITGEWSECSVTCGKGYKQRL 1636
Score = 35.0 bits (79), Expect = 0.073
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 21/101 (20%)
Query: 134 SPWSPCSTSCGLGVSTRISNVNAQCWPEQES------------RLCNLRPCDVDIHTLIK 181
SP+ CS +CG G+ T I N PE ++ + CN PC
Sbjct: 595 SPFGTCSRTCGGGIKTAIRECNR---PEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDF-- 649
Query: 182 AGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRC 222
++C +F + G + + PKY G+ M +RC
Sbjct: 650 RDEQCAHF----DGKHFNINGLLPNVRWVPKYSGILMKDRC 686
Score = 31.2 bits (69), Expect = 1.1
Identities = 23/64 (35%), Positives = 27/64 (42%), Gaps = 13/64 (20%)
Query: 136 WSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIK--AGKKCLAVYQPE 193
W CS SCG+GV R +V +Q S LC HT +K K C VY E
Sbjct: 1686 WGSCSVSCGVGVMQR--SVQCLTNEDQPSHLC---------HTDLKPEERKTCRNVYNCE 1734
Query: 194 ASMN 197
N
Sbjct: 1735 LPQN 1738
Score = 28.5 bits (62), Expect = 6.8
Identities = 14/31 (45%), Positives = 14/31 (45%), Gaps = 6/31 (19%)
Query: 126 HRNCIAYTSP------WSPCSTSCGLGVSTR 150
HR C P WS CS SCG GV R
Sbjct: 1490 HRKCRGGRCPKWKAGAWSQCSVSCGRGVQQR 1520
Score = 28.1 bits (61), Expect = 8.9
Identities = 21/76 (27%), Positives = 28/76 (36%), Gaps = 17/76 (22%)
Query: 107 RPRYAIGVCAHAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRI----------SNVNA 156
RPR A H +G + W T PW CS++C G R+ +N
Sbjct: 1315 RPRSASPSRTHVLGGNQ-WR------TGPWGACSSTCAGGSQRRVVVCQDENGYTANDCV 1367
Query: 157 QCWPEQESRLCNLRPC 172
+ E R C PC
Sbjct: 1368 ERIKPDEQRACESGPC 1383
>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
Length = 480
Score = 36.6 bits (83), Expect = 0.025
Identities = 25/79 (31%), Positives = 32/79 (40%), Gaps = 14/79 (17%)
Query: 9 LAAVTAAAASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSL 68
L + AA AS L+ A AP + P C+ P CPP P C G +
Sbjct: 12 LLLLLAAPASAQLSRAGRSAPLA-----------AGCPDRCE-PARCPPQPEHCEGGRA- 58
Query: 69 ITDGCECCKMCAQQLGDNC 87
D C CC++C G C
Sbjct: 59 -RDACGCCEVCGAPEGAAC 76
>gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo
sapiens]
Length = 1074
Score = 36.6 bits (83), Expect = 0.025
Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 10/51 (19%)
Query: 132 YTSPWSPCSTSCGLGVSTR-------ISNVNAQCWPE---QESRLCNLRPC 172
+++PWSPCS SC G TR ++ +C P+ R CN +PC
Sbjct: 975 FSTPWSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLRPSRKRPCNSQPC 1025
Score = 30.0 bits (66), Expect = 2.4
Identities = 10/19 (52%), Positives = 11/19 (57%)
Query: 132 YTSPWSPCSTSCGLGVSTR 150
YT PW CS+ CG G R
Sbjct: 915 YTGPWGECSSECGSGTQRR 933
>gi|223718260 ADAMTS-like 2 precursor [Homo sapiens]
Length = 951
Score = 36.2 bits (82), Expect = 0.033
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 10/65 (15%)
Query: 121 EVEAWHRNCIA-YTSPWSPCSTSCGLGVSTRI------SNVNAQCWPEQE---SRLCNLR 170
E + R C YTSPWS C+ +CG+GV R +++ C P + + C+L+
Sbjct: 846 ESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQ 905
Query: 171 PCDVD 175
PC +
Sbjct: 906 PCPTE 910
Score = 29.3 bits (64), Expect = 4.0
Identities = 12/27 (44%), Positives = 15/27 (55%), Gaps = 4/27 (14%)
Query: 133 TSPWSPCSTSCGLGVSTRISNVNAQCW 159
TS WS CS +CG G R+ +CW
Sbjct: 628 TSSWSECSRTCGEGYQFRV----VRCW 650
>gi|41281450 ADAMTS-like 2 precursor [Homo sapiens]
Length = 951
Score = 36.2 bits (82), Expect = 0.033
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 10/65 (15%)
Query: 121 EVEAWHRNCIA-YTSPWSPCSTSCGLGVSTRI------SNVNAQCWPEQE---SRLCNLR 170
E + R C YTSPWS C+ +CG+GV R +++ C P + + C+L+
Sbjct: 846 ESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQ 905
Query: 171 PCDVD 175
PC +
Sbjct: 906 PCPTE 910
Score = 29.3 bits (64), Expect = 4.0
Identities = 12/27 (44%), Positives = 15/27 (55%), Gaps = 4/27 (14%)
Query: 133 TSPWSPCSTSCGLGVSTRISNVNAQCW 159
TS WS CS +CG G R+ +CW
Sbjct: 628 TSSWSECSRTCGEGYQFRV----VRCW 650
>gi|169174934 PREDICTED: similar to ADAMTS-like 2 [Homo sapiens]
Length = 660
Score = 36.2 bits (82), Expect = 0.033
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 10/65 (15%)
Query: 121 EVEAWHRNCIA-YTSPWSPCSTSCGLGVSTRI------SNVNAQCWPEQE---SRLCNLR 170
E + R C YTSPWS C+ +CG+GV R +++ C P + + C+L+
Sbjct: 555 ESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQ 614
Query: 171 PCDVD 175
PC +
Sbjct: 615 PCPTE 619
Score = 29.3 bits (64), Expect = 4.0
Identities = 12/27 (44%), Positives = 15/27 (55%), Gaps = 4/27 (14%)
Query: 133 TSPWSPCSTSCGLGVSTRISNVNAQCW 159
TS WS CS +CG G R+ +CW
Sbjct: 337 TSSWSECSRTCGEGYQFRV----VRCW 359
>gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens]
Length = 476
Score = 35.8 bits (81), Expect = 0.043
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 6/65 (9%)
Query: 39 LEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCAQQLGDNC--TEAAICDPH 96
L S P C+ P CP + P C LG + + D C CC++C + C + C P
Sbjct: 34 LHTQPSCPAVCQ-PTRCP-ALPTCALGTTPVFDLCRCCRVCPAAEREVCGGAQGQPCAP- 90
Query: 97 RGLYC 101
GL C
Sbjct: 91 -GLQC 94
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.136 0.478
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,583,673
Number of Sequences: 37866
Number of extensions: 640138
Number of successful extensions: 3217
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 2851
Number of HSP's gapped (non-prelim): 412
length of query: 280
length of database: 18,247,518
effective HSP length: 101
effective length of query: 179
effective length of database: 14,423,052
effective search space: 2581726308
effective search space used: 2581726308
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.