Search of human proteins with 18373305

Search of human proteins with 18373305

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18373305 arrestin domain containing 2 isoform 1 [Homo
sapiens]
         (407 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18373305 arrestin domain containing 2 isoform 1 [Homo sapiens]     821   0.0  
gi|71040100 arrestin domain containing 2 isoform 2 [Homo sapiens]     695   0.0  
gi|32698736 arrestin domain containing 3 [Homo sapiens]               431   e-121
gi|190886442 arrestin domain containing 4 [Homo sapiens]              348   5e-96
gi|171184421 thioredoxin interacting protein [Homo sapiens]           261   1e-69
gi|22748653 arrestin domain containing 1 [Homo sapiens]               101   1e-21
gi|122937478 arrestin domain containing 5 [Homo sapiens]               74   2e-13
gi|24797153 faciogenital dysplasia protein [Homo sapiens]              39   0.008
gi|10880136 arrestin beta 1 isoform A [Homo sapiens]                   32   1.0  
gi|10880134 arrestin beta 1 isoform B [Homo sapiens]                   32   1.0  
gi|239753049 PREDICTED: hypothetical protein [Homo sapiens]            32   1.0  
gi|239747589 PREDICTED: hypothetical protein XP_002347780 [Homo ...    32   1.0  
gi|110349719 titin isoform N2-A [Homo sapiens]                         31   2.3  
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    30   3.0  
gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens]     30   3.9  
gi|30089935 transmembrane protein 132A isoform a [Homo sapiens]        30   3.9  
gi|30089937 transmembrane protein 132A isoform b [Homo sapiens]        30   3.9  
gi|21361581 solute carrier family 6 (neurotransmitter transporte...    30   5.1  
gi|169790923 5-methyltetrahydrofolate-homocysteine methyltransfe...    30   5.1  
gi|46094081 development and differentiation enhancing factor 1 [...    30   5.1  
gi|54792138 helicase with zinc finger domain [Homo sapiens]            29   6.7  
gi|238550105 SET domain containing 6 isoform b [Homo sapiens]          29   8.7  
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]             29   8.7  
gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate...    29   8.7  

>gi|18373305 arrestin domain containing 2 isoform 1 [Homo sapiens]
          Length = 407

 Score =  821 bits (2121), Expect = 0.0
 Identities = 407/407 (100%), Positives = 407/407 (100%)

Query: 1   MLFDKVKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWT 60
           MLFDKVKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWT
Sbjct: 1   MLFDKVKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWT 60

Query: 61  ESRSAGSSTAYTQSYSERVEVVSHRATLLAPDTGETTTLPPGRHEFLFSFQLPPTLVTSF 120
           ESRSAGSSTAYTQSYSERVEVVSHRATLLAPDTGETTTLPPGRHEFLFSFQLPPTLVTSF
Sbjct: 61  ESRSAGSSTAYTQSYSERVEVVSHRATLLAPDTGETTTLPPGRHEFLFSFQLPPTLVTSF 120

Query: 121 EGKHGSVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKVARSWYCN 180
           EGKHGSVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKVARSWYCN
Sbjct: 121 EGKHGSVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKVARSWYCN 180

Query: 181 RGLVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQKRAVV 240
           RGLVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQKRAVV
Sbjct: 181 RGLVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQKRAVV 240

Query: 241 ASLAGEPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSKLLLELPL 300
           ASLAGEPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSKLLLELPL
Sbjct: 241 ASLAGEPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSKLLLELPL 300

Query: 301 VIGTIPLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAALGQSPFP 360
           VIGTIPLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAALGQSPFP
Sbjct: 301 VIGTIPLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAALGQSPFP 360

Query: 361 LPQDPDMSLEGPFFAYIQEFRYRPPPLYSEEDPNPLLGDMRPRCMTC 407
           LPQDPDMSLEGPFFAYIQEFRYRPPPLYSEEDPNPLLGDMRPRCMTC
Sbjct: 361 LPQDPDMSLEGPFFAYIQEFRYRPPPLYSEEDPNPLLGDMRPRCMTC 407


>gi|71040100 arrestin domain containing 2 isoform 2 [Homo sapiens]
          Length = 402

 Score =  695 bits (1793), Expect = 0.0
 Identities = 348/402 (86%), Positives = 363/402 (90%), Gaps = 5/402 (1%)

Query: 6   VKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWTESRSA 65
           V++F+++L     G    + GG+ + GRVLLE ++  RV AL ++ARG A  HW E RS 
Sbjct: 6   VRSFALELARGPGGA---YRGGERLCGRVLLEAAAPLRVRALEVKARGGAATHWLEGRSV 62

Query: 66  GSSTAYTQSYSERVEVVSHRATLLAPDTGETTTLPPGRHEFLFSFQLPPTLVTSFEGKHG 125
           G + A +  Y+   E    R  LL  DTGETTTLPPGRHEFLFSFQLPPTLVTSFEGKHG
Sbjct: 63  GVN-AVSSDYAA-AETYLRRRQLLLRDTGETTTLPPGRHEFLFSFQLPPTLVTSFEGKHG 120

Query: 126 SVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKVARSWYCNRGLVS 185
           SVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKVARSWYCNRGLVS
Sbjct: 121 SVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKVARSWYCNRGLVS 180

Query: 186 LSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQKRAVVASLAG 245
           LSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQKRAVVASLAG
Sbjct: 181 LSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQKRAVVASLAG 240

Query: 246 EPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSKLLLELPLVIGTI 305
           EPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSKLLLELPLVIGTI
Sbjct: 241 EPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSKLLLELPLVIGTI 300

Query: 306 PLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAALGQSPFPLPQDP 365
           PLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAALGQSPFPLPQDP
Sbjct: 301 PLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAALGQSPFPLPQDP 360

Query: 366 DMSLEGPFFAYIQEFRYRPPPLYSEEDPNPLLGDMRPRCMTC 407
           DMSLEGPFFAYIQEFRYRPPPLYSEEDPNPLLGDMRPRCMTC
Sbjct: 361 DMSLEGPFFAYIQEFRYRPPPLYSEEDPNPLLGDMRPRCMTC 402


>gi|32698736 arrestin domain containing 3 [Homo sapiens]
          Length = 414

 Score =  431 bits (1109), Expect = e-121
 Identities = 219/412 (53%), Positives = 285/412 (69%), Gaps = 9/412 (2%)

Query: 1   MLFDKVKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWT 60
           M+  KVK+ ++  D       PV+S G  V+GRV LE++   RV +L++ ARG A V WT
Sbjct: 1   MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWT 60

Query: 61  ESRSAGSSTAYTQSYSERVEVVSHRATLLAPDTGETT------TLPPGRHEFLFSFQLPP 114
           ESR+AGS+TAYTQ+Y+E VE  +H+  L+  +  +        T+  GRHE+ FSF+LP 
Sbjct: 61  ESRNAGSNTAYTQNYTEEVEYFNHKDILIGHERDDDNSEEGFHTIHSGRHEYAFSFELPQ 120

Query: 115 T-LVTSFEGKHGSVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKV 173
           T L TSFEG+HGSVRY +KA LHRPW+   + +K FTV E +DINTP+LL+PQAG +EK 
Sbjct: 121 TPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPSLLSPQAGTKEKT 180

Query: 174 ARSWYCNRGLVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGAR 233
              W+C  G +SLSAKI+RKGYTPGE I +FAEI+N S+R V+P+AA+ QTQ F A+G  
Sbjct: 181 LCCWFCTSGPISLSAKIERKGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKM 240

Query: 234 KQKRAVVASLAGEPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSK 293
           K+ + +VA+L GE +  G+   W G+ L+IPPV PSIL C ++ V+Y+L V VDIPG   
Sbjct: 241 KEVKQLVANLRGESLSSGKTETWNGKLLKIPPVSPSILDCSIIRVEYSLMVYVDIPGAMD 300

Query: 294 LLLELPLVIGTIPLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAA 353
           L L LPLVIGTIPLHPFGSR+SSV S  S  ++W   +LPERPEAPP Y+EVV + E+  
Sbjct: 301 LFLNLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLSLSLPERPEAPPSYAEVVTE-EQRR 359

Query: 354 LGQSPFPLPQDPDMSLEGPFFAYIQEFRYRPPPLYSEEDPNP-LLGDMRPRC 404
              +P     D + +L+GP FAYIQEFR+ PPPLYSE DPNP    D RP C
Sbjct: 360 NNLAPVSACDDFERALQGPLFAYIQEFRFLPPPLYSEIDPNPDQSADDRPSC 411


>gi|190886442 arrestin domain containing 4 [Homo sapiens]
          Length = 418

 Score =  348 bits (893), Expect = 5e-96
 Identities = 187/376 (49%), Positives = 249/376 (66%), Gaps = 6/376 (1%)

Query: 24  FSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWTESRS--AGSSTAYTQSYSERVEV 81
           +S G+ VAG VLLE S    + ALRL A+GRA   W  S    A +STA    +SE VE 
Sbjct: 32  YSSGETVAGHVLLEASEPVALRALRLEAQGRATAAWGPSTCPRASASTAALAVFSE-VEY 90

Query: 82  VSHRATLLAPDTGE-TTTLPPGRHEFLFSFQLPPT-LVTSFEGKHGSVRYCIKATLHRPW 139
           ++ R +L  P  GE    L PG+HEF F FQLP   LVTSF GK+GS++YC++A L RP 
Sbjct: 91  LNVRLSLREPPAGEGIILLQPGKHEFPFRFQLPSEPLVTSFTGKYGSIQYCVRAVLERPK 150

Query: 140 VPARRARKVFTVIEPVDINTPALLAPQAGAREKVARSWYCNRGLVSLSAKIDRKGYTPGE 199
           VP +  ++   V+  VD+NTPALL P    +EK+   W+   G VSLSAKI+RKGY  GE
Sbjct: 151 VPDQSVKRELQVVSHVDVNTPALLTPVLKTQEKMVGCWFFTSGPVSLSAKIERKGYCNGE 210

Query: 200 VIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQKRAVVASLAGEPVGPGQRALWQGR 259
            IP++AEI+N S+R ++P+AA+ QTQT++A G  K  R +VA++ G  +  G    W G+
Sbjct: 211 AIPIYAEIENCSSRLIVPKAAIFQTQTYLASGKTKTIRHMVANVRGNHIASGSTDTWNGK 270

Query: 260 ALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSKLLLELPLVIGTIPLHPFGSRSSSVGS 319
            L+IPPV PSIL C ++ VDY+L V + IPG  KL+LELPLVIGTIP + FGSR+SS+ S
Sbjct: 271 TLKIPPVTPSILDCCIIRVDYSLAVYIHIPGAKKLMLELPLVIGTIPYNGFGSRNSSIAS 330

Query: 320 HASFLLDWRLGALPERPEAPPEYSEVVADTEEAALGQSPFPLPQDPDMSLEGPFFAYIQE 379
             S  + W    LPE+PEAPP Y++VV++ EE +    P+P P + +  +  P FA IQE
Sbjct: 331 QFSMDMSWLTLTLPEQPEAPPNYADVVSE-EEFSRHIPPYPQPPNCEGEVCCPVFACIQE 389

Query: 380 FRYRPPPLYSEEDPNP 395
           FR++PPPLYSE DP+P
Sbjct: 390 FRFQPPPLYSEVDPHP 405


>gi|171184421 thioredoxin interacting protein [Homo sapiens]
          Length = 391

 Score =  261 bits (666), Expect = 1e-69
 Identities = 152/399 (38%), Positives = 230/399 (57%), Gaps = 23/399 (5%)

Query: 1   MLFDKVKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWT 60
           ++F K+K+F V  +      E V+  G+ VAGRV++E+    RV A+R+ A G A V W 
Sbjct: 2   VMFKKIKSFEVVFNDP----EKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWM 57

Query: 61  ESRSAGSSTAYTQSYSERVEVVSHRATLLAPD--TGETTTL---PPGRHEFLFSFQLPP- 114
           +          +Q   +  E + +  TLL  D  TGE   +   P  ++E+ F F+LP  
Sbjct: 58  QG---------SQQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQG 108

Query: 115 TLVTSFEGKHGSVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKVA 174
            L TSF+GK+G V Y +KA L RP  P +  +K F V++ VD+NTP L+AP +  +EK  
Sbjct: 109 PLGTSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKV 168

Query: 175 RSWYCNRGLVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARK 234
              +   G VS+SA+IDRKG+  G+ I + A+ +N  +R V+P+AA+V   T++A G  K
Sbjct: 169 SCMFIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTK 228

Query: 235 QKRAVVASLAGEPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSKL 294
                ++S+ G  +  G  A W+G++LR+  + PSIL C +L V+Y+L + V +PG+ K+
Sbjct: 229 VLTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKV 288

Query: 295 LLELPLVIGTIPLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAAL 354
           +L+LPLVIG+       SR+SS+ S  S  + W    +P+ PEAPP Y +V+   E+  L
Sbjct: 289 ILDLPLVIGS--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVI--PEDHRL 344

Query: 355 GQSPFPLPQDPDMSLEGPFFAYIQEFRYRPPPLYSEEDP 393
                PL  D D S + P F Y  EF++ PPP Y+E DP
Sbjct: 345 ESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDP 383


>gi|22748653 arrestin domain containing 1 [Homo sapiens]
          Length = 433

 Score =  101 bits (252), Expect = 1e-21
 Identities = 85/308 (27%), Positives = 147/308 (47%), Gaps = 27/308 (8%)

Query: 5   KVKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWTESRS 64
           +V+ F + L         V+S G+ +AG V + L +     A+R+   G   V      +
Sbjct: 3   RVQLFEISLSHGRV----VYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGVS-----N 53

Query: 65  AGSSTAYTQSYSERVEVVSHRATLLAPDTGETTTLPPGRHEFLFSFQLPPTLVTSFEGKH 124
             + TA+       VE     ++L   D G   +LP G H F F F LP T  TSFEG  
Sbjct: 54  KANDTAWV------VEEGYFNSSLSLADKG---SLPAGEHSFPFQFLLPATAPTSFEGPF 104

Query: 125 GSVRYCIKATLHRP-WVPARRARKVFTVIEPVDINT-PALLAPQAGAREKVARSWYCNRG 182
           G + + ++A +H P +    +   VF ++ P+++N+ P +  P   +  K         G
Sbjct: 105 GKIVHQVRAAIHTPRFSKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTG 164

Query: 183 LVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLP-RAAVVQTQTFMARGARKQKRAVVA 241
            V L+A  D +GY  G+ + + A+++N S +   P  A+++Q  ++ A+      R  +A
Sbjct: 165 SVVLTASTDLRGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHDVR-TIA 223

Query: 242 SLAGEPVGPGQRALWQGRALRIPPVGPSIL-HCRVLHVDYALKVCVDIPGTSKLLLELPL 300
            + G  V   +RA W  + L +P +  S L  C ++H+DY L+V +  P   +  + LP+
Sbjct: 224 EVEGAGVKAWRRAQWHEQIL-VPALPQSALPGCSLIHIDYYLQVSLKAP---EATVTLPV 279

Query: 301 VIGTIPLH 308
            IG I ++
Sbjct: 280 FIGNIAVN 287


>gi|122937478 arrestin domain containing 5 [Homo sapiens]
          Length = 342

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 74/296 (25%), Positives = 133/296 (44%), Gaps = 25/296 (8%)

Query: 23  VFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWTESRSAGSSTAYTQSY--SERVE 80
           ++  G ++ G+V+L L+S      +++   GR +V W+E   AG+S  Y+++   + + +
Sbjct: 30  IYLAGSSIKGQVILTLNSTLVDPIVKVELVGRGYVEWSEE--AGASCDYSRNVICNNKAD 87

Query: 81  VVSHRATLLAPDTGETTTLPPGRHEFLFSFQLPPTLVTSFEGKHGSVRYCIKAT-LHRPW 139
            V    T    D      L  G H F F F LPP L ++F  K G V Y ++A+ + R  
Sbjct: 88  YVHKTKTFPVEDNW----LSAGSHTFDFHFNLPPRLPSTFTSKFGHVFYFVQASCMGREH 143

Query: 140 VPARRARKVFTVIEPVDI---NTPALLAPQAGAREKVARSWYCNRGLVSLSAKIDRKGYT 196
           + A+  ++++ +++        TP        A EKV+ +  C +G V L  +++R  +T
Sbjct: 144 ILAK--KRMYLLVQGTSTFHKETPFQNPLFVEAEEKVSYN-CCRQGTVCLQIQMERNTFT 200

Query: 197 PGEVIPVFAEIDNGSTR----PVLPRAAVVQTQTFMARGARKQKRAVVASLAGEPVGPGQ 252
           PGE +    EI+N +++     V    A +Q + F     R+ +      L  E   P  
Sbjct: 201 PGEKVVFTTEINNQTSKCIKTVVFALYAHIQYEGFTPSAERRSRLDSSELLRQEANTPVT 260

Query: 253 R--ALWQGRALRIP---PVGPSILHCRVLHVDYALKVCVDIP-GTSKLLLELPLVI 302
           R           +P    V  S     ++H  Y L   V +P   + L  ++P++I
Sbjct: 261 RFNTTKVVSTFNLPLLLSVSSSTQDGEIMHTRYELVTTVHLPWSLTSLKAKVPIII 316


>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
          Length = 961

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 58/212 (27%), Positives = 78/212 (36%), Gaps = 48/212 (22%)

Query: 197 PGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQKRAVVASLAGEPVGPGQRALW 256
           PG   P  A+ D G++ P L           +AR  R    A+   L  + VGP   +L 
Sbjct: 23  PGAAPPACADSDPGASEPGL-----------LAR--RGSGSALGGPLDPQFVGPSDTSLG 69

Query: 257 QGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSK----LLLELPLVIG-TIPLHPFG 311
                R+ P GPS  H R L   Y L+     PG  +    L+  L L  G ++  HP G
Sbjct: 70  AAPGHRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQSLEPHPEG 129

Query: 312 SRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAALGQSPFPLPQDPDMSLEG 371
                                P+R  + P           + L ++P P PQ P      
Sbjct: 130 ---------------------PQRLRSDPGPPTETPSQRPSPLKRAPGPKPQVP------ 162

Query: 372 PFFAYIQEFRYRPPPLYSEEDP--NPLLGDMR 401
           P  +Y+Q  R  PPPL     P   PL  D R
Sbjct: 163 PKPSYLQMPR-MPPPLEPIPPPPSRPLPADPR 193


>gi|10880136 arrestin beta 1 isoform A [Homo sapiens]
          Length = 418

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 33/123 (26%), Positives = 49/123 (39%), Gaps = 12/123 (9%)

Query: 102 GRHEFLFSFQLPPTLVTSF--------EGKHGSVRYCIKA-TLHRPWVPARRARKVFTVI 152
           G H + F+F++PP L  S          GK   V Y +KA           +   V  VI
Sbjct: 109 GEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVI 168

Query: 153 EPVDINTPALLAPQAGAREKVARSWYCNRGLVSLSAKIDRKGYTPGEVIPVFAEIDNGST 212
             V    P    PQ  A  +  R +  +   + L A +D++ Y  GE I V   + N + 
Sbjct: 169 RKVQY-APERPGPQPTA--ETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTN 225

Query: 213 RPV 215
           + V
Sbjct: 226 KTV 228


>gi|10880134 arrestin beta 1 isoform B [Homo sapiens]
          Length = 410

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 33/123 (26%), Positives = 49/123 (39%), Gaps = 12/123 (9%)

Query: 102 GRHEFLFSFQLPPTLVTSF--------EGKHGSVRYCIKA-TLHRPWVPARRARKVFTVI 152
           G H + F+F++PP L  S          GK   V Y +KA           +   V  VI
Sbjct: 109 GEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVI 168

Query: 153 EPVDINTPALLAPQAGAREKVARSWYCNRGLVSLSAKIDRKGYTPGEVIPVFAEIDNGST 212
             V    P    PQ  A  +  R +  +   + L A +D++ Y  GE I V   + N + 
Sbjct: 169 RKVQY-APERPGPQPTA--ETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTN 225

Query: 213 RPV 215
           + V
Sbjct: 226 KTV 228


>gi|239753049 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 183

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 5/57 (8%)

Query: 216 LPRAAVVQTQTFMARGARKQKRAVVAS-----LAGEPVGPGQRALWQGRALRIPPVG 267
           L R     T +  A G+R+++R  + +      A   VG GQR  W  R  R PP+G
Sbjct: 102 LARGISSWTVSISALGSRRRERTTLVARREQEAARAAVGSGQRVRWSDRPQRSPPLG 158


>gi|239747589 PREDICTED: hypothetical protein XP_002347780 [Homo
           sapiens]
          Length = 183

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 5/57 (8%)

Query: 216 LPRAAVVQTQTFMARGARKQKRAVVAS-----LAGEPVGPGQRALWQGRALRIPPVG 267
           L R     T +  A G+R+++R  + +      A   VG GQR  W  R  R PP+G
Sbjct: 102 LARGISSWTVSISALGSRRRERTTLVARREQEAARAAVGSGQRVRWSDRPQRSPPLG 158


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 14/36 (38%), Positives = 23/36 (63%), Gaps = 2/36 (5%)

Query: 331   ALPERPEAPPEYSEVVADTEEAALGQSPFPLPQDPD 366
             A+P +PE+PP   EV  + EE AL + P  + ++P+
Sbjct: 10653 AIPPKPESPP--PEVFEEPEEVALEEPPAEVVEEPE 10686


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 2/67 (2%)

Query: 332 LPERPEAPPEYSEVVADTEEAA--LGQSPFPLPQDPDMSLEGPFFAYIQEFRYRPPPLYS 389
           +P  P  PP    + A    A   LG+  +P     D   E P  A I E    PPP  +
Sbjct: 930 MPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEAN 989

Query: 390 EEDPNPL 396
             DP P+
Sbjct: 990 CTDPEPV 996


>gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens]
          Length = 1537

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 9/63 (14%)

Query: 336 PEAPPEYSEVVADTEEA-ALGQSPFPLPQDPDMSLEGPFFAYIQEFRYRPPPLYSEEDPN 394
           PE  P+ ++   D   A  + Q+    PQD   S   PF        Y+ PP      PN
Sbjct: 422 PERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPF--------YQLPPSVQRHSPN 473

Query: 395 PLL 397
           PLL
Sbjct: 474 PLL 476


>gi|30089935 transmembrane protein 132A isoform a [Homo sapiens]
          Length = 1024

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 36/137 (26%), Positives = 52/137 (37%), Gaps = 32/137 (23%)

Query: 237 RAVVASLAGEPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDY----ALKVCVDIPGTS 292
           RAV    A  P  P  R L+  +    PP G   L C  LH  +    A + C   P   
Sbjct: 124 RAVSVEAAVTPAEPYARVLFHLKGQDWPP-GSGSLPCARLHATHPAGTAHQACRFQPSLG 182

Query: 293 KLLLELPLVIGTIPLHPFGSRSSSVGSHASFLLD---------------------WRLGA 331
             ++EL L     P H F S++S+  +  ++ L+                       +G 
Sbjct: 183 ACVVELEL-----PSHWF-SQASTTRAELAYTLEPAAEGPGGCGSGEENDPGEQALPVGG 236

Query: 332 LPERPEAPPEYSEVVAD 348
           +  RP  PP+Y EV  D
Sbjct: 237 VELRPADPPQYQEVPLD 253


>gi|30089937 transmembrane protein 132A isoform b [Homo sapiens]
          Length = 1023

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 36/137 (26%), Positives = 52/137 (37%), Gaps = 32/137 (23%)

Query: 237 RAVVASLAGEPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDY----ALKVCVDIPGTS 292
           RAV    A  P  P  R L+  +    PP G   L C  LH  +    A + C   P   
Sbjct: 124 RAVSVEAAVTPAEPYARVLFHLKGQDWPP-GSGSLPCARLHATHPAGTAHQACRFQPSLG 182

Query: 293 KLLLELPLVIGTIPLHPFGSRSSSVGSHASFLLD---------------------WRLGA 331
             ++EL L     P H F S++S+  +  ++ L+                       +G 
Sbjct: 183 ACVVELEL-----PSHWF-SQASTTRAELAYTLEPAAEGPGGCGSGEENDPGEQALPVGG 236

Query: 332 LPERPEAPPEYSEVVAD 348
           +  RP  PP+Y EV  D
Sbjct: 237 VELRPADPPQYQEVPLD 253


>gi|21361581 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 13 [Homo sapiens]
          Length = 602

 Score = 29.6 bits (65), Expect = 5.1
 Identities = 16/43 (37%), Positives = 21/43 (48%)

Query: 209 NGSTRPVLPRAAVVQTQTFMARGARKQKRAVVASLAGEPVGPG 251
           NG T+PV P     +    + RG    K   V S+AGE +G G
Sbjct: 11  NGETKPVYPVMEKKEEDGTLERGHWNNKMEFVLSVAGEIIGLG 53


>gi|169790923 5-methyltetrahydrofolate-homocysteine
           methyltransferase [Homo sapiens]
          Length = 1265

 Score = 29.6 bits (65), Expect = 5.1
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 6/50 (12%)

Query: 326 DWRLGALPERPE---APPEYSEVVADTEEAALGQSPFPLPQDPDMSLEGP 372
           +WR G + ER E          ++ DTEEA L Q  +P P +    +EGP
Sbjct: 665 EWRNGPVEERLEYALVKGIEKHIIEDTEEARLNQKKYPRPLN---IIEGP 711


>gi|46094081 development and differentiation enhancing factor 1 [Homo
            sapiens]
          Length = 1129

 Score = 29.6 bits (65), Expect = 5.1
 Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 6/82 (7%)

Query: 328  RLGALPERP---EAPPEYSEVVADTEEAALGQSPFPLPQDPDMSLEGPFFAYIQEFRYRP 384
            +L  LP++P   + PP+ +E+    +   L   P  LP  P +   G      Q     P
Sbjct: 926  QLAELPQKPPPGDLPPKPTELAPKPQIGDLPPKPGELPPKPQL---GDLPPKPQLSDLPP 982

Query: 385  PPLYSEEDPNPLLGDMRPRCMT 406
             P   +  P P LGD+  +  T
Sbjct: 983  KPQMKDLPPKPQLGDLLAKSQT 1004


>gi|54792138 helicase with zinc finger domain [Homo sapiens]
          Length = 1942

 Score = 29.3 bits (64), Expect = 6.7
 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 10/82 (12%)

Query: 324  LLDWRLGALPERP-EAPPEYSEVVADTEEAALGQSP-FPLPQDPDMSLEGP---FFAYIQ 378
            LL+ +   LPE+P + PP+ ++VV   +++ L Q P  P PQ       GP   FF    
Sbjct: 1379 LLNQQQNNLPEQPNQIPPQPNQVV--QQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAV 1436

Query: 379  EFRYRPPP---LYSEEDPNPLL 397
              R + PP   +  E+ P P+L
Sbjct: 1437 AHRPQSPPAEAVIPEQQPPPML 1458


>gi|238550105 SET domain containing 6 isoform b [Homo sapiens]
          Length = 449

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 3/72 (4%)

Query: 176 SWYCNRGLVSLSAKI--DRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGAR 233
           SW C R  + LS K+   R+G   G  +     +  G    V+PRAA++   T    G  
Sbjct: 27  SW-CRRVGLELSPKVAVSRQGTVAGYGMVARESVQAGELLFVVPRAALLSQHTCSIGGLL 85

Query: 234 KQKRAVVASLAG 245
           +++R  + S +G
Sbjct: 86  ERERVALQSQSG 97


>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
          Length = 518

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 20/67 (29%), Positives = 27/67 (40%), Gaps = 6/67 (8%)

Query: 298 LPLVIGTIPLHPFGSRSSSVGS------HASFLLDWRLGALPERPEAPPEYSEVVADTEE 351
           +P +  T P  P  S + S+ S        +F + W        P  P E SEV   T+ 
Sbjct: 336 VPEISVTTPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQP 395

Query: 352 AALGQSP 358
           AA  Q P
Sbjct: 396 AAGAQEP 402


>gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
           [Homo sapiens]
          Length = 1043

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 2/80 (2%)

Query: 288 IPGTSKLLLELPLVIGTIPLHPFGSRS-SSVGSHASFLLDWRLGALPERPEAPPEYSEVV 346
           + G+S++ +     + ++   P G+ + ++VGS     LD   G    RP  PP+ ++V 
Sbjct: 356 VTGSSQVHMSRHFKVWSLRRDPRGAPAWATVGSWRDGQLDLEPGGASARPP-PPQGAQVW 414

Query: 347 ADTEEAALGQSPFPLPQDPD 366
                  L + PF   +DPD
Sbjct: 415 PKLRVVTLLEHPFVFARDPD 434


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,456,905
Number of Sequences: 37866
Number of extensions: 884397
Number of successful extensions: 2409
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2377
Number of HSP's gapped (non-prelim): 40
length of query: 407
length of database: 18,247,518
effective HSP length: 105
effective length of query: 302
effective length of database: 14,271,588
effective search space: 4310019576
effective search space used: 4310019576
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.