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Search of human proteins with 18105063
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18105063 vacuolar protein sorting 45A [Homo sapiens]
(570 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18105063 vacuolar protein sorting 45A [Homo sapiens] 1120 0.0
gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens] 129 6e-30
gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens] 125 8e-29
gi|33469966 vesicle transport-related protein isoform a [Homo sa... 121 2e-27
gi|118600975 syntaxin binding protein 3 [Homo sapiens] 118 1e-26
gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens] 115 1e-25
gi|33469978 vesicle transport-related protein isoform b [Homo sa... 114 3e-25
gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens] 111 2e-24
gi|18105056 vacuolar protein sorting 33A [Homo sapiens] 67 6e-11
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 36 0.083
gi|38044112 restin isoform b [Homo sapiens] 36 0.083
gi|4506751 restin isoform a [Homo sapiens] 36 0.083
gi|56786157 activating transcription factor 6 [Homo sapiens] 34 0.32
gi|115430110 hypothetical protein LOC153643 [Homo sapiens] 33 0.70
gi|45269141 multimerin 1 [Homo sapiens] 33 0.92
gi|13775178 testis expressed 13B [Homo sapiens] 31 2.7
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 31 3.5
gi|20357504 dystonin isoform 1eB precursor [Homo sapiens] 30 4.6
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 30 4.6
gi|5174457 kinetochore associated 2 [Homo sapiens] 30 4.6
gi|54234040 vacuolar protein sorting 54 isoform 2 [Homo sapiens] 30 4.6
gi|54234034 vacuolar protein sorting 54 isoform 1 [Homo sapiens] 30 4.6
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 30 4.6
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 30 4.6
gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens] 30 6.0
gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens] 30 6.0
gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens] 30 6.0
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 30 6.0
gi|118918413 MICAL C-terminal like [Homo sapiens] 30 6.0
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 30 6.0
>gi|18105063 vacuolar protein sorting 45A [Homo sapiens]
Length = 570
Score = 1120 bits (2898), Expect = 0.0
Identities = 570/570 (100%), Positives = 570/570 (100%)
Query: 1 MNVVFAVKQYISKMIEDSGPGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNR 60
MNVVFAVKQYISKMIEDSGPGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNR
Sbjct: 1 MNVVFAVKQYISKMIEDSGPGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNR 60
Query: 61 EIMKHLKAICFLRPTKENVDYIIQELRRPKYTIYFIYFSNVISKSDVKSLAEADEQEVVA 120
EIMKHLKAICFLRPTKENVDYIIQELRRPKYTIYFIYFSNVISKSDVKSLAEADEQEVVA
Sbjct: 61 EIMKHLKAICFLRPTKENVDYIIQELRRPKYTIYFIYFSNVISKSDVKSLAEADEQEVVA 120
Query: 121 EVQEFYGDYIAVNPHLFSLNILGCCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLS 180
EVQEFYGDYIAVNPHLFSLNILGCCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLS
Sbjct: 121 EVQEFYGDYIAVNPHLFSLNILGCCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLS 180
Query: 181 SEAAKRLAECVKQVITKEYELFEFRRTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELL 240
SEAAKRLAECVKQVITKEYELFEFRRTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELL
Sbjct: 181 SEAAKRLAECVKQVITKEYELFEFRRTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELL 240
Query: 241 GINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPK 300
GINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPK
Sbjct: 241 GINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPK 300
Query: 301 EQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQ 360
EQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQ
Sbjct: 301 EQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQ 360
Query: 361 NDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYR 420
NDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYR
Sbjct: 361 NDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYR 420
Query: 421 KLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKG 480
KLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKG
Sbjct: 421 KLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKG 480
Query: 481 RLKENLYPYLGPSTLRDRPQDIIVFVIGGATYEEALTVYNLNRTTPGVRIVLGGTTVHNT 540
RLKENLYPYLGPSTLRDRPQDIIVFVIGGATYEEALTVYNLNRTTPGVRIVLGGTTVHNT
Sbjct: 481 RLKENLYPYLGPSTLRDRPQDIIVFVIGGATYEEALTVYNLNRTTPGVRIVLGGTTVHNT 540
Query: 541 KSFLEEVLASGLHSRSKESSQVTSRSASRR 570
KSFLEEVLASGLHSRSKESSQVTSRSASRR
Sbjct: 541 KSFLEEVLASGLHSRSKESSQVTSRSASRR 570
>gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens]
Length = 593
Score = 129 bits (325), Expect = 6e-30
Identities = 131/578 (22%), Positives = 250/578 (43%), Gaps = 75/578 (12%)
Query: 23 KVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDYI 82
KVL+MD + I+S S+IL + + + E I+ + RE + L+AI L PT+++V +
Sbjct: 29 KVLIMDHPSMRILSSCCKMSDILAEGITIVEDINKR-REPIPSLEAIYLLSPTEKSVQAL 87
Query: 83 IQELRRPK---YTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSL 139
I++ + Y I+F++ + L + +VV ++E + ++ +FSL
Sbjct: 88 IKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGRSRLAKVVKTLKEIHLAFLPYEAQVFSL 147
Query: 140 NI------LGCCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLAECVKQ 193
+ L C QL Q + L +L++ P IRY+ E +LA V
Sbjct: 148 DAPHSTYNLYCPFRAEERTRQLEVLAQQIATLCATLQEYPAIRYRKGPEDTAQLAHAVLA 207
Query: 194 VITKEYELFEFRRTEVPPL----------LLILDRCDDAITPLLNQWTYQAMVHELLGIN 243
+ + + P L LLI+DR D ++PLL++ T+QAM ++LL I
Sbjct: 208 KLNAF-------KADTPSLGEGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLDIE 260
Query: 244 NNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQ 303
+ G+S+ + VL E+D+ + +++ A++ + L+ F + K
Sbjct: 261 QDTYRY-ETTGLSEAREKAVLLDEDDDLWVELRHMHIADVSKKVTELLRTFCESKRLTTD 319
Query: 304 KLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDH 363
K +I D+ ++ PQ++K S H+ + + + + ++ ++ VEQ+LA +D
Sbjct: 320 K-ANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKHF-KGSVEKLCSVEQDLAMGSDA 377
Query: 364 -----SSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEK 418
+++ I +L + V +D R+++LY L S +L L+ + S
Sbjct: 378 EGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNGVSEENLAKLIQHANVQAHSSL 437
Query: 419 YR---KLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLD 475
R +L V GG S P++ + T Q ++ P + + ++
Sbjct: 438 IRNLEQLGGTVTNPGGSGT--SSRLEPRERMEPTYQL-----------SRWTPVIKDVME 484
Query: 476 HLIKGRLKENLYPYLGPSTLRDRPQ-----------------------DIIVFVIGGATY 512
++ RL NL+P++ Q +IV+V+GG
Sbjct: 485 DAVEDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGIEARAGPRLIVYVMGGVAM 544
Query: 513 EEALTVYNLNRTTPGV-RIVLGGTTVHNTKSFLEEVLA 549
E Y + R T G +++G + + FL+++ A
Sbjct: 545 SEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKA 582
>gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens]
Length = 590
Score = 125 bits (315), Expect = 8e-29
Identities = 130/575 (22%), Positives = 245/575 (42%), Gaps = 72/575 (12%)
Query: 23 KVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDYI 82
KVL+MD + I+S S+IL + + + E I+ + RE + L+AI L PT++ +
Sbjct: 29 KVLIMDHPSMRILSSCCKMSDILAEGITIVEDINKR-REPIPSLEAIYLLSPTEKALIKD 87
Query: 83 IQELRRPKYTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSLNI- 141
Q Y I+F++ + L + +VV ++E + ++ +FSL+
Sbjct: 88 FQGTPTFTYKAAHIFFTDTCPEPLFSELGRSRLAKVVKTLKEIHLAFLPYEAQVFSLDAP 147
Query: 142 -----LGCCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLAECVKQVIT 196
L C QL Q + L +L++ P IRY+ E +LA V +
Sbjct: 148 HSTYNLYCPFRAEERTRQLEVLAQQIATLCATLQEYPAIRYRKGPEDTAQLAHAVLAKLN 207
Query: 197 KEYELFEFRRTEVPPL----------LLILDRCDDAITPLLNQWTYQAMVHELLGINNNR 246
+ + P L LLI+DR D ++PLL++ T+QAM ++LL I +
Sbjct: 208 AF-------KADTPSLGEGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLDIEQDT 260
Query: 247 IDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLE 306
G+S+ + VL E+D+ + +++ A++ + L+ F + K K
Sbjct: 261 YRY-ETTGLSEAREKAVLLDEDDDLWVELRHMHIADVSKKVTELLRTFCESKRLTTDK-A 318
Query: 307 SIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDH--- 363
+I D+ ++ PQ++K S H+ + + + + ++ ++ VEQ+LA +D
Sbjct: 319 NIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKHF-KGSVEKLCSVEQDLAMGSDAEGE 377
Query: 364 --SSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYR- 420
+++ I +L + V +D R+++LY L S +L L+ + S R
Sbjct: 378 KIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNGVSEENLAKLIQHANVQAHSSLIRN 437
Query: 421 --KLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLI 478
+L V GG S P++ + T Q ++ P + + ++ +
Sbjct: 438 LEQLGGTVTNPGGSGT--SSRLEPRERMEPTYQL-----------SRWTPVIKDVMEDAV 484
Query: 479 KGRLKENLYPYLGPSTLRDRPQ-----------------------DIIVFVIGGATYEEA 515
+ RL NL+P++ Q +IV+V+GG E
Sbjct: 485 EDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGIEARAGPRLIVYVMGGVAMSEM 544
Query: 516 LTVYNLNRTTPGV-RIVLGGTTVHNTKSFLEEVLA 549
Y + R T G +++G + + FL+++ A
Sbjct: 545 RAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKA 579
>gi|33469966 vesicle transport-related protein isoform a [Homo
sapiens]
Length = 642
Score = 121 bits (304), Expect = 2e-27
Identities = 139/617 (22%), Positives = 261/617 (42%), Gaps = 102/617 (16%)
Query: 20 PGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENV 79
P KVL+ D+ I+S + + E+ + L + S +R+ + + A+ F+ PT+EN+
Sbjct: 41 PVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHS-DRDPIPDVPAVYFVMPTEENI 99
Query: 80 DYIIQELRRPKYTIYFIYFSNVISKSDVKSLAEA----DEQEVVAEVQEFYGDYIAVNPH 135
D + Q+LR Y Y++ F + IS+S ++ +A A VA+V + Y ++I +
Sbjct: 100 DRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDD 159
Query: 136 LFSLNILGCCQGRNWDPAQ---------------LSRTTQGLTALLLSLKKCPMIRYQLS 180
+F L C Q + + + L ++L P+IR
Sbjct: 160 MFVL----CNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRG 215
Query: 181 SEAA-------KRLAECVKQVITKEYE-------LFEFRRTEVPPLLLILDRCDDAITPL 226
+ A K+L E ++ + F F+R PLL+++DR D TPL
Sbjct: 216 TAAEMVAVKLDKKLRENLRDARNSLFTGDTLGAGQFSFQR----PLLVLVDRNIDLATPL 271
Query: 227 LNQWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAEN---------DEFYANNMY 277
+ WTYQA+VH++L + NR++L G+ +N D+F+ +
Sbjct: 272 HHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDLTPVDKFWQKHKG 331
Query: 278 LNFAEIGSNIKNLMEDFQKKKPKEQQKLESI------------------ADMKAFVENYP 319
F E+ +++ +E ++ ++ E ++L+SI A + + V + P
Sbjct: 332 SPFPEVAESVQQELESYRAQE-DEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLP 390
Query: 320 QFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKV 379
+ + + H V + + R L E E+++ + +L +I + +P
Sbjct: 391 ELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDKSLLDI---ISDPDA 447
Query: 380 -TEFDAARLVMLYALHYERHSSNS-LPGLMMDLRNKGVS----------EKYRKLVSAVV 427
T D RL ++Y + ++ S + L L + G + + + K+ SA
Sbjct: 448 GTPEDKMRLFLIYYISTQQAPSEADLEQYKKALTDAGCNLNPLQYIKQWKAFTKMASAPA 507
Query: 428 EYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPF-LHETLDHL--IKGRLKE 484
YG + L S + QF+ ++GV+N+ + Q + LD+L +K +
Sbjct: 508 SYGSTTTKPMGLLS--RVMNTGSQFV--MEGVKNLVLKQQNLPVTRILDNLMEMKSNPET 563
Query: 485 NLYPYLGPSTLRDRP----------QDIIVFVIGGATYEEALTVYNLNRTTPGVRIVLGG 534
+ Y Y P LR Q+ IVFV+GG Y E + + + G I+ G
Sbjct: 564 DDYRYFDPKMLRGNDSSVPRNKNPFQEAIVFVVGGGNYIEYQNLVDYIKGKQGKHILYGC 623
Query: 535 TTVHNTKSFLEEVLASG 551
+ + N F++++ G
Sbjct: 624 SELFNATQFIKQLSQLG 640
>gi|118600975 syntaxin binding protein 3 [Homo sapiens]
Length = 592
Score = 118 bits (296), Expect = 1e-26
Identities = 118/568 (20%), Positives = 253/568 (44%), Gaps = 67/568 (11%)
Query: 23 KVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDYI 82
K++L+D+ TT +++ +++L++ + + E I +NRE ++ +KA+ F+ PT ++VD
Sbjct: 33 KIMLLDEFTTKLLASCCKMTDLLEEGITVVENI-YKNREPVRQMKALYFITPTSKSVDCF 91
Query: 83 IQELRRP---KYTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSL 139
+ + KY +IYF++ ++ + +A + + +E +I +++L
Sbjct: 92 LHDFASKSENKYKAAYIYFTD-FCPDNLFNKIKASCSKSIRRCKEINISFIPHESQVYTL 150
Query: 140 NIL-----------GCCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSS-EAAKRL 187
++ G +G++ A + + + +L + P +RY+ + A +L
Sbjct: 151 DVPDAFYYCYSPDPGNAKGKD---AIMETMADQIVTVCATLDENPGVRYKSKPLDNASKL 207
Query: 188 AECVKQVITKEYELFE--FRRTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNN 245
A+ V++ + Y++ E + + LLI+DR D ++ +L++ T+QAM ++LL I N
Sbjct: 208 AQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIEN- 266
Query: 246 RIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKL 305
D + K+ +E +L E D+ + + + A + I LM++ K + K
Sbjct: 267 --DTYKYKTDGKE-KEAILE-EEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKT 322
Query: 306 ESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSS 365
S++ + ++ P F+K H+ + + + N+ ++ + EQ+LA D
Sbjct: 323 -SLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKF-KLNIEKLCKTEQDLALGTDAEG 380
Query: 366 -----ALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYR 420
+++ + +L N D R ++LY + +L L+ +++ + S+ R
Sbjct: 381 QKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNVKIENESDMIR 440
Query: 421 KLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKG 480
V + +G L + A + ++ PF+ + ++ I
Sbjct: 441 NWSYLGVPIVPQSQQGKPLRKDRSAEETFQ------------LSRWTPFIKDIMEDAIDN 488
Query: 481 RLKENLYPYL----------GPSTLRDRPQ-----------DIIVFVIGGATYEEALTVY 519
RL +PY G + R +P+ +IVFVIGG TY E Y
Sbjct: 489 RLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRCAY 548
Query: 520 NLNRTTPGVRIVLGGTTVHNTKSFLEEV 547
+++ +++G T V K L+++
Sbjct: 549 EVSQAHKSCEVIIGSTHVLTPKKLLDDI 576
>gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens]
Length = 603
Score = 115 bits (287), Expect = 1e-25
Identities = 119/587 (20%), Positives = 262/587 (44%), Gaps = 67/587 (11%)
Query: 23 KVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDYI 82
KVL++D+ + ++S ++I+ + + + E I+ + RE + L+A+ + P++++V +
Sbjct: 29 KVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKR-REPLPSLEAVYLITPSEKSVHSL 87
Query: 83 IQELRRP---KYTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSL 139
I + + P KY ++F++ + L ++ +V+ + E ++ ++SL
Sbjct: 88 ISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSL 147
Query: 140 NILGCCQGRNWDPAQ-------LSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLAECVK 192
+ Q + P + L R + + L +LK+ P +RY+ + LA+ ++
Sbjct: 148 DSADSFQSF-YSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQ 206
Query: 193 QVITKEYELFEFRRTEVPPL----LLILDRCDDAITPLLNQWTYQAMVHELLGINNNRID 248
+ Y+ + E P LLILDR D +P+L++ T+QAM ++LL I N+ +
Sbjct: 207 DKLDA-YKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIEND-VY 264
Query: 249 LSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESI 308
GI + + VL E+D+ + + + AE+ + ++DF K + ++
Sbjct: 265 KYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTM 324
Query: 309 ADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDH----- 363
D+ ++ PQ++K S H+ + + + + + ++ VEQ+LA D
Sbjct: 325 RDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHY-QGTVDKLCRVEQDLAMGTDAEGEKI 383
Query: 364 SSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYRKLV 423
++ I +L + V+ +D R+++LY + +L L +++ + + +++
Sbjct: 384 KDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKL---IQHAQIPPEDSEII 440
Query: 424 SAVVEYGGKRVRGSDL---FSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKG 480
+ + G V S L P+ I++Q + ++ P + + ++ I+
Sbjct: 441 TNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQ--------LSRWTPIIKDIMEDTIED 492
Query: 481 RLKENLYPYL------------------------GPSTLRDRPQDIIVFVIGGATYEEAL 516
+L YPY+ P R P+ +I+F++GG + E
Sbjct: 493 KLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPR-LIIFILGGVSLNEMR 551
Query: 517 TVYNLNRTTPGVRIVLGGTTVHNTKSFLEEVLASGLHSRSKESSQVT 563
Y + + +++G T + FL ++ H +ESS+V+
Sbjct: 552 CAYEVTQANGKWEVLIGSTHILTPTKFLMDL----RHPDFRESSRVS 594
>gi|33469978 vesicle transport-related protein isoform b [Homo
sapiens]
Length = 575
Score = 114 bits (284), Expect = 3e-25
Identities = 129/578 (22%), Positives = 243/578 (42%), Gaps = 101/578 (17%)
Query: 59 NREIMKHLKAICFLRPTKENVDYIIQELRRPKYTIYFIYFSNVISKSDVKSLAEA----D 114
+R+ + + A+ F+ PT+EN+D + Q+LR Y Y++ F + IS+S ++ +A A
Sbjct: 12 DRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAAS 71
Query: 115 EQEVVAEVQEFYGDYIAVNPHLFSLNILGCCQGRNWDPAQ---------------LSRTT 159
VA+V + Y ++I + +F L C Q + + +
Sbjct: 72 AVTQVAKVFDQYLNFITLEDDMFVL----CNQNKELVSYRAINRPDITDTEMETVMDTIV 127
Query: 160 QGLTALLLSLKKCPMIRYQLSSEAA-------KRLAECVKQVITKEYE-------LFEFR 205
L ++L P+IR + A K+L E ++ + F F+
Sbjct: 128 DSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDTLGAGQFSFQ 187
Query: 206 RTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLS 265
R PLL+++DR D TPL + WTYQA+VH++L + NR++L G+
Sbjct: 188 R----PLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPK 243
Query: 266 AEN---------DEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESI-------- 308
+N D+F+ + F E+ +++ +E ++ ++ E ++L+SI
Sbjct: 244 RKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQE-DEVKRLKSIMGLEGEDE 302
Query: 309 ----------ADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELA 358
A + + V + P+ + + H V + + R L E E+++
Sbjct: 303 GAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIM 362
Query: 359 CQNDHSSALQNIKRLLQNPKV-TEFDAARLVMLYALHYERHSSNS-LPGLMMDLRNKGVS 416
+ +L +I + +P T D RL ++Y + ++ S + L L + G +
Sbjct: 363 SKTTLDKSLLDI---ISDPDAGTPEDKMRLFLIYYISTQQAPSEADLEQYKKALTDAGCN 419
Query: 417 ----------EKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQH 466
+ + K+ SA YG + L S + QF+ ++GV+N+ +
Sbjct: 420 LNPLQYIKQWKAFTKMASAPASYGSTTTKPMGLLS--RVMNTGSQFV--MEGVKNLVLKQ 475
Query: 467 QPF-LHETLDHL--IKGRLKENLYPYLGPSTLRDRP----------QDIIVFVIGGATYE 513
Q + LD+L +K + + Y Y P LR Q+ IVFV+GG Y
Sbjct: 476 QNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRGNDSSVPRNKNPFQEAIVFVVGGGNYI 535
Query: 514 EALTVYNLNRTTPGVRIVLGGTTVHNTKSFLEEVLASG 551
E + + + G I+ G + + N F++++ G
Sbjct: 536 EYQNLVDYIKGKQGKHILYGCSELFNATQFIKQLSQLG 573
>gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens]
Length = 594
Score = 111 bits (277), Expect = 2e-24
Identities = 113/569 (19%), Positives = 253/569 (44%), Gaps = 63/569 (11%)
Query: 23 KVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDYI 82
KVL++D+ + ++S ++I+ + + + E I+ + RE + L+A+ + P++++V +
Sbjct: 29 KVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKR-REPLPSLEAVYLITPSEKSVHSL 87
Query: 83 IQELRRP---KYTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSL 139
I + + P KY ++F++ + L ++ +V+ + E ++ ++SL
Sbjct: 88 ISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSL 147
Query: 140 NILGCCQGRNWDPAQ-------LSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLAECVK 192
+ Q + P + L R + + L +LK+ P +RY+ + LA+ ++
Sbjct: 148 DSADSFQSF-YSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQ 206
Query: 193 QVITKEYELFEFRRTEVPPL----LLILDRCDDAITPLLNQWTYQAMVHELLGINNNRID 248
+ Y+ + E P LLILDR D +P+L++ T+QAM ++LL I N+ +
Sbjct: 207 DKLDA-YKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIEND-VY 264
Query: 249 LSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESI 308
GI + + VL E+D+ + + + AE+ + ++DF K + ++
Sbjct: 265 KYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTM 324
Query: 309 ADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDH----- 363
D+ ++ PQ++K S H+ + + + + + ++ VEQ+LA D
Sbjct: 325 RDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHY-QGTVDKLCRVEQDLAMGTDAEGEKI 383
Query: 364 SSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYRKLV 423
++ I +L + V+ +D R+++LY + +L L +++ + + +++
Sbjct: 384 KDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKL---IQHAQIPPEDSEII 440
Query: 424 SAVVEYGGKRVRGSDL---FSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKG 480
+ + G V S L P+ I++Q + ++ P + + ++ I+
Sbjct: 441 TNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQ--------LSRWTPIIKDIMEDTIED 492
Query: 481 RLKENLYPYL------------------------GPSTLRDRPQDIIVFVIGGATYEEAL 516
+L YPY+ P R P+ +I+F++GG + E
Sbjct: 493 KLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPR-LIIFILGGVSLNEMR 551
Query: 517 TVYNLNRTTPGVRIVLGGTTVHNTKSFLE 545
Y + + +++G T + + L+
Sbjct: 552 CAYEVTQANGKWEVLIGSTHILTPQKLLD 580
>gi|18105056 vacuolar protein sorting 33A [Homo sapiens]
Length = 596
Score = 66.6 bits (161), Expect = 6e-11
Identities = 82/375 (21%), Positives = 148/375 (39%), Gaps = 37/375 (9%)
Query: 6 AVKQYISKMIEDSGPGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKH 65
AV++ + + + D G K ++ D+ TG ++ S + + EV +
Sbjct: 18 AVRRELREFL-DKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKGNRLPAADV 76
Query: 66 LKAICFLRPTKENVDYIIQEL-----RRPK--YTIYFIYFSNVISKSDVKSLAEADEQEV 118
I F+RP E +D I + + R P + I F+ +++ + +K L
Sbjct: 77 KNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLLCEQRLKDLGVLGS--- 133
Query: 119 VAEVQEFYGDYIAVNPHLFSLNILGCCQG--RNWDPAQLSRTTQGLTALLLSLKKCPMIR 176
+E+ D I + L S+ G + D L +GL L P I
Sbjct: 134 FIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLMTLQALYGTIPQIF 193
Query: 177 YQLSSEAAKRLAECVKQVITKEYEL---FEFRRTEVPPL---LLILDRCDDAITPLLNQW 230
+ EC +QV + F + + P+ LL+LDR D +TPL Q
Sbjct: 194 GK---------GECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPLATQL 244
Query: 231 TYQAMVHELLGINNNRIDLSRVPGISKDLRE--VVLSAENDEFYANNMYLNFAEIGSNIK 288
TY+ ++ E+ GI N+ + L K + L E + N+ +AEI
Sbjct: 245 TYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNF 304
Query: 289 NLMEDFQKKKPK-------EQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRL 341
N + KK K E+ +++ ++K FV P + G+++ H ++ + +
Sbjct: 305 NAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAELIKDV 364
Query: 342 VSERNLLEVSEVEQE 356
+ + + VEQE
Sbjct: 365 TTSEDFFDKLTVEQE 379
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 36.2 bits (82), Expect = 0.083
Identities = 73/358 (20%), Positives = 138/358 (38%), Gaps = 56/358 (15%)
Query: 53 ERIDSQNREIMKHLKAICFL---RPTKENVDYIIQELRRPKYTIYFIYFSNVISKSDVKS 109
E ID +N E+ + +K + +P +N +I+EL+R K + + D+K
Sbjct: 1841 EEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQR-KVKKLENQLEGKVEEVDLKP 1899
Query: 110 LAEADEQEVVA-----------------EVQEFYGDYIAVNPHLFSLNILGCCQGRNWDP 152
+ E + +E + +++E G+ + L +L L +
Sbjct: 1900 MKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLT 1959
Query: 153 AQLSRTTQGLTA-LLLSLKKCPMIRYQLSSEAAKRLAECVKQVITKEYELFEFRRTEVPP 211
Q T G+T +L ++ + E+ K L E K+ + E ++ R + P
Sbjct: 1960 LQRKLKTTGMTVDQVLGIR---------ALESEKELEELKKRNLDLENDILYMRAHQALP 2010
Query: 212 LLLILDRCDDAITPLLNQWTY-QAMVHEL-LGINNNRIDLSRVPGISKD---LREVVLSA 266
D + L Q Y Q +H L + + + GI D RE L
Sbjct: 2011 R-------DSVVEDLHLQNRYLQEKLHALEKQFSKDTYSKPSISGIESDDHCQREQELQK 2063
Query: 267 ENDEFYANNMYLNFAEIGSN------------IKNLMEDFQKKKPKEQQKLESIADMKAF 314
EN + + N+ L F +N +K + E +K+K + Q+KL +
Sbjct: 2064 ENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVQRKLGHVRGSGRS 2123
Query: 315 VENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSA-LQNIK 371
+ P+ +K G + K V V + + + + + SE + +N+ A L+ +K
Sbjct: 2124 GKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMANIEQENEKLKAELEKLK 2181
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 36.2 bits (82), Expect = 0.083
Identities = 32/134 (23%), Positives = 70/134 (52%), Gaps = 10/134 (7%)
Query: 255 ISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAF 314
+ + ++E V E N + + ++ N+ ++ F++K +E+Q +++ K
Sbjct: 824 VQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKA----KEK 879
Query: 315 VEN-YPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQ-NIKR 372
+EN + KMSG S +T + + RL ER +V E++ +L N+++S LQ +I+
Sbjct: 880 LENDIAEIMKMSGDNSSQLTKMNDELRL-KER---DVEELQLKLTKANENASFLQKSIED 935
Query: 373 LLQNPKVTEFDAAR 386
+ + ++ +AA+
Sbjct: 936 MTVKAEQSQQEAAK 949
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 36.2 bits (82), Expect = 0.083
Identities = 32/134 (23%), Positives = 70/134 (52%), Gaps = 10/134 (7%)
Query: 255 ISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAF 314
+ + ++E V E N + + ++ N+ ++ F++K +E+Q +++ K
Sbjct: 859 VQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKA----KEK 914
Query: 315 VEN-YPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQ-NIKR 372
+EN + KMSG S +T + + RL ER +V E++ +L N+++S LQ +I+
Sbjct: 915 LENDIAEIMKMSGDNSSQLTKMNDELRL-KER---DVEELQLKLTKANENASFLQKSIED 970
Query: 373 LLQNPKVTEFDAAR 386
+ + ++ +AA+
Sbjct: 971 MTVKAEQSQQEAAK 984
>gi|56786157 activating transcription factor 6 [Homo sapiens]
Length = 670
Score = 34.3 bits (77), Expect = 0.32
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 287 IKNLMEDFQKKKPKEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERN 346
IKN Q +K K++ L A +KA + Q KK +GT+ + +L +VSE
Sbjct: 314 IKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKR------QLDEVVSENQ 367
Query: 347 LLEVSEVEQELAC 359
L+V ++ + C
Sbjct: 368 RLKVPSPKRRVVC 380
>gi|115430110 hypothetical protein LOC153643 [Homo sapiens]
Length = 452
Score = 33.1 bits (74), Expect = 0.70
Identities = 30/121 (24%), Positives = 58/121 (47%), Gaps = 14/121 (11%)
Query: 255 ISKDLREVVLSAENDEFYANNMYLNFAE-----IGSNIKNLMEDFQKKKPKEQQKLESIA 309
+S +L E V EN++ + N +L + + I +K L E +K + K ++KL
Sbjct: 302 LSSNLYEEV---ENNKKWTENQFLKYRKDHLGHINECLKVLQEKLEKSENKMEEKL---L 355
Query: 310 DMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQN 369
+ + VEN+ +K +SK + +LS+ + + E+E QN++ S ++
Sbjct: 356 QLSSKVENFINTQKQETQLSKVKHMENKLSKKMEQMEKQIWGELE---TMQNEYQSGFKS 412
Query: 370 I 370
I
Sbjct: 413 I 413
>gi|45269141 multimerin 1 [Homo sapiens]
Length = 1228
Score = 32.7 bits (73), Expect = 0.92
Identities = 29/117 (24%), Positives = 55/117 (47%), Gaps = 11/117 (9%)
Query: 259 LREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKK---PKEQQKLESIADMKAFV 315
+R++V E + + N+M A++ + +L ED + + K + + SIA + FV
Sbjct: 387 IRDIV--REQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFV 444
Query: 316 ---ENYPQFKKMSGTVSKHVTVVGELSRLVSERNL--LEVSEVEQELACQNDHSSAL 367
EN P + + H+ V + L E+ + LEV + E A + +HS ++
Sbjct: 445 LVQENRPTLTDIV-ELRNHIVNVRQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSI 500
>gi|13775178 testis expressed 13B [Homo sapiens]
Length = 312
Score = 31.2 bits (69), Expect = 2.7
Identities = 46/210 (21%), Positives = 89/210 (42%), Gaps = 22/210 (10%)
Query: 259 LREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQ-KKKPKEQQKLESIADMKAFVEN 317
+ ++ + EFY N+ L++ E+ ++ ++ED + + KE S+A F
Sbjct: 22 IEKMARHTKGPEFYFENISLSWEEVEDKLRAILEDSEVPSEVKEACTWGSLALGVRFAHR 81
Query: 318 YPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNP 377
Q + + + + LV NL E+ E +QE+ C N+ + LQ L
Sbjct: 82 QGQLQNRRVQWLQGFAKLHRSAALVLASNLTELKE-QQEMEC-NEATFQLQ-----LTET 134
Query: 378 KVTEFDAARLVMLYALHYE-------RHSSNSLPGLMMDLRN--KGVSEKYRKLVSAVVE 428
+ E R ++ + L + + + PGL + +G E+ ++ V+A
Sbjct: 135 SLAEVQRERDMLRWKLFHAELAPPQGQGQATVFPGLATAGGDWTEGAGEQEKEAVAAAGA 194
Query: 429 YGGKRVRGSDLFSPKDAVAITKQFLKGLKG 458
GGK G + ++ +A + L+GL G
Sbjct: 195 AGGK---GEERYA--EAGPAPAEVLQGLGG 219
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 30.8 bits (68), Expect = 3.5
Identities = 21/93 (22%), Positives = 49/93 (52%), Gaps = 7/93 (7%)
Query: 291 MEDFQKKKPKEQQKLESIADM--KAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLL 348
M D Q+K P ++++++S AD+ + F++ ++ + +++++ G+ + + E +
Sbjct: 1049 MVDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEEEIK 1108
Query: 349 EVSEVEQELACQNDHSSALQNIK-RLLQNPKVT 380
E + A +S LQ K +L+N K+T
Sbjct: 1109 RCKETSEHGA----YSDLLQRQKATVLENSKLT 1137
>gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]
Length = 3062
Score = 30.4 bits (67), Expect = 4.6
Identities = 39/208 (18%), Positives = 85/208 (40%), Gaps = 35/208 (16%)
Query: 291 MEDFQKKKPKEQQKLESIADM--KAFVENYPQFKKMSGTVSKHVTVVGE-LSRLVSERNL 347
M D Q+K P ++++++S AD+ + F++ ++ + +++++ G+ L RL E
Sbjct: 1049 MVDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEEEKS 1108
Query: 348 LEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLM 407
LE + E H + +++ + N T DA + + P
Sbjct: 1109 LEEEKKE--------HVEKAKELQKWVSNISKTLKDAEK-------------AGKPPFSK 1147
Query: 408 MDLRNKGVSEKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQ-----------FLKGL 456
+ ++ +S K +L A+ + D + ++ + KQ F + L
Sbjct: 1148 QKISSEEISTKKEQLSEALQTIQLFLAKHGDKMTDEERNELEKQVKTLQESYNLLFSESL 1207
Query: 457 KGVENVYTQHQPFLHETLDHLIKGRLKE 484
K ++ T + E LD +I G + +
Sbjct: 1208 KQLQESQTSGDVKVEEKLDKVIAGTIDQ 1235
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 30.4 bits (67), Expect = 4.6
Identities = 24/114 (21%), Positives = 52/114 (45%), Gaps = 5/114 (4%)
Query: 257 KDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAFVE 316
K+ +E+ S E ++ ++ + L + + ++ + +EQQ +I ++K E
Sbjct: 910 KEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSE 969
Query: 317 NYP-QFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQN 369
Q + + G + V EL + + ++++ QELA + + S LQN
Sbjct: 970 QKKKQIEALQGELKIAVLQKTELENKLQQ----QLTQAAQELAAEKEKISVLQN 1019
>gi|5174457 kinetochore associated 2 [Homo sapiens]
Length = 642
Score = 30.4 bits (67), Expect = 4.6
Identities = 29/136 (21%), Positives = 62/136 (45%), Gaps = 18/136 (13%)
Query: 295 QKKKPKEQQKLESIADMKAFVE-NYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEV 353
++++ KE +LES+ +KA ++ + +++ + H ++ + ++E E++ V
Sbjct: 283 EQEREKEPNRLESLRKLKASLQGDVQKYQAYMSNLESHSAILDQKLNGLNE----EIARV 338
Query: 354 EQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNK 413
E E ++ LQNI + N K + D R+ H N L + L K
Sbjct: 339 ELECETIKQENTRLQNI---IDNQKYSVADIERI---------NHERNELQQTINKL-TK 385
Query: 414 GVSEKYRKLVSAVVEY 429
+ + +KL + ++Y
Sbjct: 386 DLEAEQQKLWNEELKY 401
>gi|54234040 vacuolar protein sorting 54 isoform 2 [Homo sapiens]
Length = 965
Score = 30.4 bits (67), Expect = 4.6
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Query: 15 IEDSGPGMKVLLMDKETTGIVSMVYTQSEILQKE---VYLFERIDSQNREIMK 64
+ + P ++VLL E G + ++ T E+LQ+E ++ F + SQ E+ K
Sbjct: 284 VHQTQPTVQVLLSTSEFVGALDLIATTQEVLQQELQGIHSFRHLGSQLCELEK 336
>gi|54234034 vacuolar protein sorting 54 isoform 1 [Homo sapiens]
Length = 977
Score = 30.4 bits (67), Expect = 4.6
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Query: 15 IEDSGPGMKVLLMDKETTGIVSMVYTQSEILQKE---VYLFERIDSQNREIMK 64
+ + P ++VLL E G + ++ T E+LQ+E ++ F + SQ E+ K
Sbjct: 296 VHQTQPTVQVLLSTSEFVGALDLIATTQEVLQQELQGIHSFRHLGSQLCELEK 348
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 30.4 bits (67), Expect = 4.6
Identities = 44/216 (20%), Positives = 92/216 (42%), Gaps = 28/216 (12%)
Query: 261 EVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLES--IADMKAFVENY 318
++ + A+ + + + E+ + + E+ + K + Q+KL++ I+ +A EN
Sbjct: 1442 QLEMQAKEHDERIKQLQVELCEMKQKPEEIGEE-SRAKQQIQRKLQAALISRKEALKENK 1500
Query: 319 PQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPK 378
+++S L+R ER +++VE +++ QN + LLQ +
Sbjct: 1501 SLQEELS------------LARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEER 1548
Query: 379 ---VTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYRKLVSAVVEYGGKRVR 435
+TE D + L + S+S L + L +G++E KLV + ++
Sbjct: 1549 DKLITEMDRSLL-------ENQSLSSSCESLKLAL--EGLTEDKEKLVKEIESLKSSKIA 1599
Query: 436 GSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLH 471
S + K + K++ L+ ENV + + H
Sbjct: 1600 ESTEWQEKHK-ELQKEYEILLQSYENVSNEAERIQH 1634
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 30.4 bits (67), Expect = 4.6
Identities = 33/139 (23%), Positives = 57/139 (41%), Gaps = 34/139 (24%)
Query: 259 LREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKP--------KEQQKL----- 305
LR+ + + +ND N YL +I +E + K + QQ+L
Sbjct: 524 LRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKA 583
Query: 306 -------------ESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSE 352
ES ++A +E+Y +++ +SKH V +ERNL E
Sbjct: 584 ENTRLNAELLKEKESKKRLEADIESYQS--RLAAAISKHSESVK------TERNLKLALE 635
Query: 353 VEQELACQNDHSSALQNIK 371
Q+++ Q + SSA+ +K
Sbjct: 636 RTQDVSVQVEMSSAISKVK 654
>gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]
Length = 1260
Score = 30.0 bits (66), Expect = 6.0
Identities = 27/123 (21%), Positives = 52/123 (42%), Gaps = 7/123 (5%)
Query: 255 ISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNL---MEDFQKKKPKEQQKLESIADM 311
+SK+L+ LS ++E + N + I N+ ++ K K +QK+ ++
Sbjct: 663 VSKELQIPALSTRDNENQCDYRTQNVLGLQKQITNMYPVQQNESKVNKKLRQKVNRKTEI 722
Query: 312 KAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQND----HSSAL 367
+ V + K + TV H + + + + NL + SE E D + S +
Sbjct: 723 ISEVNHLDNDKSIEYTVKSHSLFLTQKDKEIIPGNLEDPSEFETPALSTKDSGNLYDSEI 782
Query: 368 QNI 370
QN+
Sbjct: 783 QNV 785
>gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]
Length = 1265
Score = 30.0 bits (66), Expect = 6.0
Identities = 27/123 (21%), Positives = 52/123 (42%), Gaps = 7/123 (5%)
Query: 255 ISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNL---MEDFQKKKPKEQQKLESIADM 311
+SK+L+ LS ++E + N + I N+ ++ K K +QK+ ++
Sbjct: 663 VSKELQIPALSTRDNENQCDYRTQNVLGLQKQITNMYPVQQNESKVNKKLRQKVNRKTEI 722
Query: 312 KAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQND----HSSAL 367
+ V + K + TV H + + + + NL + SE E D + S +
Sbjct: 723 ISEVNHLDNDKSIEYTVKSHSLFLTQKDKEIIPGNLEDPSEFETPALSTKDSGNLYDSEI 782
Query: 368 QNI 370
QN+
Sbjct: 783 QNV 785
>gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]
Length = 1261
Score = 30.0 bits (66), Expect = 6.0
Identities = 27/123 (21%), Positives = 52/123 (42%), Gaps = 7/123 (5%)
Query: 255 ISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNL---MEDFQKKKPKEQQKLESIADM 311
+SK+L+ LS ++E + N + I N+ ++ K K +QK+ ++
Sbjct: 663 VSKELQIPALSTRDNENQCDYRTQNVLGLQKQITNMYPVQQNESKVNKKLRQKVNRKTEI 722
Query: 312 KAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQND----HSSAL 367
+ V + K + TV H + + + + NL + SE E D + S +
Sbjct: 723 ISEVNHLDNDKSIEYTVKSHSLFLTQKDKEIIPGNLEDPSEFETPALSTKDSGNLYDSEI 782
Query: 368 QNI 370
QN+
Sbjct: 783 QNV 785
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 30.0 bits (66), Expect = 6.0
Identities = 20/80 (25%), Positives = 35/80 (43%), Gaps = 6/80 (7%)
Query: 232 YQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLM 291
++ V +LLG + + R P +L + +N E N Y G + N+
Sbjct: 130 FRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFY------GPQVNNIS 183
Query: 292 EDFQKKKPKEQQKLESIADM 311
+KKK K ++K + AD+
Sbjct: 184 HTKEKKKGKAKKKRLTKADI 203
>gi|118918413 MICAL C-terminal like [Homo sapiens]
Length = 695
Score = 30.0 bits (66), Expect = 6.0
Identities = 33/135 (24%), Positives = 58/135 (42%), Gaps = 19/135 (14%)
Query: 295 QKKKPKEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVE 354
+KK + ++KLE MK V+ + K++ K + +L + + E+ V
Sbjct: 515 EKKTLRRRKKLEKA--MKQLVKQ-EELKRLY----KAQAIQRQLEEVEERQRASEIQGVR 567
Query: 355 QELACQNDHSSALQNIKRLLQN--------PKVTEFDAARLVMLYALHYERHSSNSLPGL 406
E A + + S Q+ +LLQ K+ +++ L+M L E H S L
Sbjct: 568 LEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSR----L 623
Query: 407 MMDLRNKGVSEKYRK 421
LR K + E+ +K
Sbjct: 624 EQKLREKMLKEESQK 638
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 30.0 bits (66), Expect = 6.0
Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 15/91 (16%)
Query: 288 KNLMEDFQKKKPKEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNL 347
K+L ED +KKK +++ + +A SGTV +H+ GE R +
Sbjct: 30 KSLSEDAKKKKKSNRKEDDVMA---------------SGTVKRHLKTSGECERKTKKSLE 74
Query: 348 LEVSEVEQELACQNDHSSALQNIKRLLQNPK 378
L ++ Q L+ A +++ +L+ K
Sbjct: 75 LSKEDLIQLLSIMEGELQAREDVIHMLKTEK 105
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,953,033
Number of Sequences: 37866
Number of extensions: 767801
Number of successful extensions: 2270
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2232
Number of HSP's gapped (non-prelim): 45
length of query: 570
length of database: 18,247,518
effective HSP length: 108
effective length of query: 462
effective length of database: 14,157,990
effective search space: 6540991380
effective search space used: 6540991380
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.