Search of human proteins with 17981708

Search of human proteins with 17981708

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17981708 twist homolog 2 [Homo sapiens]
         (160 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17981708 twist homolog 2 [Homo sapiens]                            316   5e-87
gi|4507741 twist [Homo sapiens]                                       231   2e-61
gi|30039710 pancreas specific transcription factor, 1a [Homo sap...    72   2e-13
gi|116805332 musculin [Homo sapiens]                                   71   3e-13
gi|38202237 transcription factor 21 [Homo sapiens]                     69   1e-12
gi|38202239 transcription factor 21 [Homo sapiens]                     69   1e-12
gi|148922889 scleraxis homolog B [Homo sapiens]                        69   2e-12
gi|186972126 scleraxis homolog A [Homo sapiens]                        69   2e-12
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo...    66   1e-11
gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]          65   3e-11
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H...    64   6e-11
gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]          61   5e-10
gi|121114306 neurogenic differentiation 1 [Homo sapiens]               60   1e-09
gi|4758506 basic helix-loop-helix transcription factor HAND1 [Ho...    59   1e-09
gi|31077092 neurogenin 2 [Homo sapiens]                                59   1e-09
gi|5031943 nescient helix loop helix 1 [Homo sapiens]                  59   1e-09
gi|153792190 neurogenic differentiation 4 [Homo sapiens]               59   2e-09
gi|98986461 neurogenic differentiation 2 [Homo sapiens]                59   2e-09
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi...    59   2e-09
gi|68989258 neurogenin 3 [Homo sapiens]                                58   4e-09
gi|23097242 nephew of atonal 3 [Homo sapiens]                          58   4e-09
gi|4885075 atonal homolog 1 [Homo sapiens]                             57   5e-09
gi|27475985 neurogenic differentiation 6 [Homo sapiens]                57   5e-09
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi...    56   2e-08
gi|38455396 neurogenin 1 [Homo sapiens]                                55   3e-08
gi|226498192 atonal homolog 8 [Homo sapiens]                           54   4e-08
gi|161484632 nescient helix loop helix 2 [Homo sapiens]                54   7e-08
gi|5031945 nescient helix loop helix 2 [Homo sapiens]                  54   7e-08
gi|21553337 atonal homolog 7 [Homo sapiens]                            53   1e-07
gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]     51   4e-07

>gi|17981708 twist homolog 2 [Homo sapiens]
          Length = 160

 Score =  316 bits (810), Expect = 5e-87
 Identities = 160/160 (100%), Positives = 160/160 (100%)

Query: 1   MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQS 60
           MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQS
Sbjct: 1   MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQS 60

Query: 61  FEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQV 120
           FEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQV
Sbjct: 61  FEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQV 120

Query: 121 LQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH 160
           LQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH
Sbjct: 121 LQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH 160


>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score =  231 bits (590), Expect = 2e-61
 Identities = 133/201 (66%), Positives = 145/201 (72%), Gaps = 41/201 (20%)

Query: 1   MEEGSSSPVSPVD-SLGTSEEELERQP----KRFGRKRRYSKKSS--------------- 40
           M++ SSSPVSP D SL  SEEE +RQ     KR GRKRR S++S+               
Sbjct: 2   MQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVG 61

Query: 41  ---EDGSPTPGKRGKK------------------GSPSAQSFEELQSQRILANVRERQRT 79
              E GSP  GKRGKK                  G  S QS+EELQ+QR++ANVRERQRT
Sbjct: 62  GGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRT 121

Query: 80  QSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHE 139
           QSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDE+D+KM SCSYVAHE
Sbjct: 122 QSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHE 181

Query: 140 RLSYAFSVWRMEGAWSMSASH 160
           RLSYAFSVWRMEGAWSMSASH
Sbjct: 182 RLSYAFSVWRMEGAWSMSASH 202


>gi|30039710 pancreas specific transcription factor, 1a [Homo
           sapiens]
          Length = 328

 Score = 72.0 bits (175), Expect = 2e-13
 Identities = 44/90 (48%), Positives = 58/90 (64%), Gaps = 9/90 (10%)

Query: 44  SPTPGKRGKKGSPSA--------QSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPT 95
           SP    RG  G+ +A        +S  ELQ  R  ANVRER+R QS+N+AF  LR  IPT
Sbjct: 133 SPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPT 192

Query: 96  LPSDK-LSKIQTLKLAARYIDFLYQVLQSD 124
           LP +K LSK+ TL+LA  YI+FL +++Q+D
Sbjct: 193 LPYEKRLSKVDTLRLAIGYINFLSELVQAD 222


>gi|116805332 musculin [Homo sapiens]
          Length = 206

 Score = 71.2 bits (173), Expect = 3e-13
 Identities = 56/153 (36%), Positives = 81/153 (52%), Gaps = 17/153 (11%)

Query: 7   SPVSPVDSLGTSEEELERQPKRF---------GRKRRYSKKSSEDGSP-TPGKRGKKGSP 56
           S  SP D+    EE+ + + +R          G KR+  + +   G+  + G  GKK  P
Sbjct: 37  SYASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLP 96

Query: 57  SAQSFEEL-QSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYI 114
           +  S  E  QSQR  AN RER R + L++AF+ L+  +P +P D KLSK+ TL+LA+ YI
Sbjct: 97  AKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYI 156

Query: 115 DFLYQVLQSDEMDNKMTSCSYVAHERLSYAFSV 147
             L Q+LQ D  +N      YV    L++ F V
Sbjct: 157 AHLRQLLQEDRYEN-----GYVHPVNLTWPFVV 184


>gi|38202237 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 69.3 bits (168), Expect = 1e-12
 Identities = 50/133 (37%), Positives = 72/133 (54%), Gaps = 17/133 (12%)

Query: 27  KRFGRKRRYSKKSS--EDGSPTPGKRG---------KKGSPSAQSFEELQSQRILANVRE 75
           K F      +++SS  E+GSP  G+ G         KK   S  S E  Q QR  AN RE
Sbjct: 29  KEFVTSNESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARE 88

Query: 76  RQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCS 134
           R R + L++AF+ L+  +P +P D KLSK+ TL+LA+ YI  L Q+L +D+ +N      
Sbjct: 89  RARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYEN-----G 143

Query: 135 YVAHERLSYAFSV 147
           Y+    L++ F V
Sbjct: 144 YIHPVNLTWPFMV 156


>gi|38202239 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 69.3 bits (168), Expect = 1e-12
 Identities = 50/133 (37%), Positives = 72/133 (54%), Gaps = 17/133 (12%)

Query: 27  KRFGRKRRYSKKSS--EDGSPTPGKRG---------KKGSPSAQSFEELQSQRILANVRE 75
           K F      +++SS  E+GSP  G+ G         KK   S  S E  Q QR  AN RE
Sbjct: 29  KEFVTSNESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARE 88

Query: 76  RQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCS 134
           R R + L++AF+ L+  +P +P D KLSK+ TL+LA+ YI  L Q+L +D+ +N      
Sbjct: 89  RARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYEN-----G 143

Query: 135 YVAHERLSYAFSV 147
           Y+    L++ F V
Sbjct: 144 YIHPVNLTWPFMV 156


>gi|148922889 scleraxis homolog B [Homo sapiens]
          Length = 201

 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 48/120 (40%), Positives = 65/120 (54%), Gaps = 5/120 (4%)

Query: 7   SPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEELQS 66
           SP+S  +  G+     + +P R    R   + +        G+R   G P  +   E + 
Sbjct: 20  SPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAG---GRRAGGGGPGGRPGREPR- 75

Query: 67  QRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDE 125
           QR  AN RER RT S+N AF ALR +IPT P+D KLSKI+TL+LA+ YI  L  VL + E
Sbjct: 76  QRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE 135


>gi|186972126 scleraxis homolog A [Homo sapiens]
          Length = 201

 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 48/120 (40%), Positives = 65/120 (54%), Gaps = 5/120 (4%)

Query: 7   SPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEELQS 66
           SP+S  +  G+     + +P R    R   + +        G+R   G P  +   E + 
Sbjct: 20  SPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAG---GRRAGGGGPGGRPGREPR- 75

Query: 67  QRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDE 125
           QR  AN RER RT S+N AF ALR +IPT P+D KLSKI+TL+LA+ YI  L  VL + E
Sbjct: 76  QRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE 135


>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
           sapiens]
          Length = 199

 Score = 65.9 bits (159), Expect = 1e-11
 Identities = 40/78 (51%), Positives = 47/78 (60%), Gaps = 1/78 (1%)

Query: 45  PTPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSK 103
           P PG   + G         +  QR  AN RER RTQS+N AF ALR +IPT P D KLSK
Sbjct: 51  PGPGGGRRAGGGGGAGPVVVVRQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSK 110

Query: 104 IQTLKLAARYIDFLYQVL 121
           I+TL+LA+ YI  L  VL
Sbjct: 111 IETLRLASSYIAHLANVL 128


>gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]
          Length = 108

 Score = 64.7 bits (156), Expect = 3e-11
 Identities = 34/57 (59%), Positives = 44/57 (77%), Gaps = 1/57 (1%)

Query: 66  SQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVL 121
           +++I  N RER R Q++N AFA LRK+IPT P D KLSK +TL+LA RYI+FL +VL
Sbjct: 2   TRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVL 58


>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
           sapiens]
          Length = 217

 Score = 63.9 bits (154), Expect = 6e-11
 Identities = 33/64 (51%), Positives = 47/64 (73%), Gaps = 1/64 (1%)

Query: 67  QRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDE 125
           +R  AN +ER+RTQS+N AFA LR+ IP +P+D KLSKI+TL+LA  YI +L  +L  D+
Sbjct: 100 RRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDD 159

Query: 126 MDNK 129
            + +
Sbjct: 160 QNGE 163


>gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]
          Length = 331

 Score = 60.8 bits (146), Expect = 5e-10
 Identities = 33/60 (55%), Positives = 43/60 (71%), Gaps = 1/60 (1%)

Query: 67  QRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDE 125
           +RI  N RER R Q++N AFA LRK+IPT P D KLSK + L+LA +YI+FL ++L   E
Sbjct: 188 RRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQE 247


>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
          Length = 356

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 36/89 (40%), Positives = 51/89 (57%), Gaps = 2/89 (2%)

Query: 37  KKSSEDGSPTPGKRG-KKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPT 95
           ++  ED    P +RG KK   +    E  + +R+ AN RER R   LN A   LRK++P 
Sbjct: 71  EEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPC 130

Query: 96  L-PSDKLSKIQTLKLAARYIDFLYQVLQS 123
              + KLSKI+TL+LA  YI  L ++L+S
Sbjct: 131 YSKTQKLSKIETLRLAKNYIWALSEILRS 159


>gi|4758506 basic helix-loop-helix transcription factor HAND1 [Homo
           sapiens]
          Length = 215

 Score = 59.3 bits (142), Expect = 1e-09
 Identities = 30/52 (57%), Positives = 40/52 (76%), Gaps = 1/52 (1%)

Query: 74  RERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSD 124
           +ER+RT+S+N AFA LR+ IP +P+D KLSKI+TL+LA  YI +L  VL  D
Sbjct: 102 KERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKD 153


>gi|31077092 neurogenin 2 [Homo sapiens]
          Length = 272

 Score = 59.3 bits (142), Expect = 1e-09
 Identities = 45/151 (29%), Positives = 77/151 (50%), Gaps = 34/151 (22%)

Query: 4   GSSSP----VSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGS--------------- 44
           GS+SP    ++P+ S  +++EE E +P   G  RR     +  G+               
Sbjct: 21  GSASPALAALTPLSS--SADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPAR 78

Query: 45  -----------PTPGKRGKKGSPSAQSFEELQ-SQRILANVRERQRTQSLNEAFAALRKI 92
                      P+  +   +G+ +A++ + ++ ++R+ AN RER R  +LN A  ALR++
Sbjct: 79  LLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREV 138

Query: 93  IPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 122
           +PT P D KL+KI+TL+ A  YI  L + L+
Sbjct: 139 LPTFPEDAKLTKIETLRFAHNYIWALTETLR 169


>gi|5031943 nescient helix loop helix 1 [Homo sapiens]
          Length = 133

 Score = 59.3 bits (142), Expect = 1e-09
 Identities = 37/84 (44%), Positives = 48/84 (57%), Gaps = 7/84 (8%)

Query: 45  PTPGKRGKKGSPSAQSFEELQSQRILAN------VRERQRTQSLNEAFAALRKIIPTLPS 98
           P PG+ G+K        E  + +R  A        RER R ++ N AFA LRK++PTLP 
Sbjct: 48  PEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPP 107

Query: 99  D-KLSKIQTLKLAARYIDFLYQVL 121
           D KLSKI+ L+LA  YI +L  VL
Sbjct: 108 DKKLSKIEILRLAICYISYLNHVL 131


>gi|153792190 neurogenic differentiation 4 [Homo sapiens]
          Length = 331

 Score = 58.9 bits (141), Expect = 2e-09
 Identities = 33/90 (36%), Positives = 52/90 (57%), Gaps = 1/90 (1%)

Query: 37  KKSSEDGSPTPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTL 96
           ++  EDG     +  KK   +    E  +++R+ AN RER R   LN+A   LR+++P  
Sbjct: 58  EEEEEDGEKPKRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCY 117

Query: 97  -PSDKLSKIQTLKLAARYIDFLYQVLQSDE 125
             + KLSKI+TL+LA  YI  L +VL++ +
Sbjct: 118 SKTQKLSKIETLRLARNYIWALSEVLETGQ 147


>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
          Length = 382

 Score = 58.5 bits (140), Expect = 2e-09
 Identities = 46/127 (36%), Positives = 63/127 (49%), Gaps = 15/127 (11%)

Query: 2   EEGSSSPVSPVDS---LGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRG-KKGSPS 57
           EEG+ + ++ V     LG  EEE E + +             E     P KRG KK   +
Sbjct: 63  EEGTEATLAEVKEEGELGGEEEEEEEEEEGL----------DEAEGERPKKRGPKKRKMT 112

Query: 58  AQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTL-PSDKLSKIQTLKLAARYIDF 116
               E  + +R  AN RER R   LN A   LRK++P    + KLSKI+TL+LA  YI  
Sbjct: 113 KARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWA 172

Query: 117 LYQVLQS 123
           L ++L+S
Sbjct: 173 LSEILRS 179


>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
           sapiens]
          Length = 280

 Score = 58.5 bits (140), Expect = 2e-09
 Identities = 30/58 (51%), Positives = 43/58 (74%), Gaps = 1/58 (1%)

Query: 66  SQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 122
           ++R+  N RER R Q++N AFA LRK++PT P D KLSK + L+LA +YI FL ++L+
Sbjct: 150 ARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLR 207


>gi|68989258 neurogenin 3 [Homo sapiens]
          Length = 214

 Score = 57.8 bits (138), Expect = 4e-09
 Identities = 45/119 (37%), Positives = 62/119 (52%), Gaps = 12/119 (10%)

Query: 5   SSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEEL 64
           +S+P SP  + G   E  E   +   RK R  +          G R +  S  A S ++ 
Sbjct: 33  TSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARR----------GGRSRPKSELALS-KQR 81

Query: 65  QSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 122
           +S+R  AN RER R  +LN A  ALR ++PT P D KL+KI+TL+ A  YI  L Q L+
Sbjct: 82  RSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLR 140


>gi|23097242 nephew of atonal 3 [Homo sapiens]
          Length = 166

 Score = 57.8 bits (138), Expect = 4e-09
 Identities = 31/61 (50%), Positives = 45/61 (73%), Gaps = 1/61 (1%)

Query: 66  SQRILANVRERQRTQSLNEAFAALRKIIPTLPSDK-LSKIQTLKLAARYIDFLYQVLQSD 124
           +QR  AN+RER+R  +LNEAF  LR+ +PT   +K LS+I+TL+LA  YI F+ ++L+S 
Sbjct: 101 AQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLESC 160

Query: 125 E 125
           E
Sbjct: 161 E 161


>gi|4885075 atonal homolog 1 [Homo sapiens]
          Length = 354

 Score = 57.4 bits (137), Expect = 5e-09
 Identities = 33/74 (44%), Positives = 50/74 (67%), Gaps = 2/74 (2%)

Query: 52  KKGSPSAQSFEELQSQRILA-NVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKL 109
           ++ +PS++    +Q QR LA N RER+R   LN AF  LR +IP+  +D KLSK +TL++
Sbjct: 144 RQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQM 203

Query: 110 AARYIDFLYQVLQS 123
           A  YI+ L ++LQ+
Sbjct: 204 AQIYINALSELLQT 217


>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
          Length = 337

 Score = 57.4 bits (137), Expect = 5e-09
 Identities = 42/130 (32%), Positives = 65/130 (50%), Gaps = 16/130 (12%)

Query: 4   GSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRG-KKGSPSAQSFE 62
           G S   +P +     EEE +R+               ED +  P +RG +K   +    E
Sbjct: 45  GKSIKRAPGEETEKEEEEEDRE--------------EEDENGLPRRRGLRKKKTTKLRLE 90

Query: 63  ELQSQRILANVRERQRTQSLNEAFAALRKIIPTL-PSDKLSKIQTLKLAARYIDFLYQVL 121
            ++ +R  AN RER R   LN+A   LRK++P    + KLSKI+TL+LA  YI  L ++L
Sbjct: 91  RVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEIL 150

Query: 122 QSDEMDNKMT 131
           +  +  + +T
Sbjct: 151 RIGKRPDLLT 160


>gi|29126247 basic helix-loop-helix family, member a15 [Homo
           sapiens]
          Length = 189

 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 35/77 (45%), Positives = 48/77 (62%), Gaps = 4/77 (5%)

Query: 44  SPTPGKRGKKG--SPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-K 100
           +P  G+R + G   P  +    +Q +R+ +N RERQR   LN AF ALR++IP + +D K
Sbjct: 52  APGEGRRRRPGPSGPGGRRDSSIQ-RRLESNERERQRMHKLNNAFQALREVIPHVRADKK 110

Query: 101 LSKIQTLKLAARYIDFL 117
           LSKI+TL LA  YI  L
Sbjct: 111 LSKIETLTLAKNYIKSL 127


>gi|38455396 neurogenin 1 [Homo sapiens]
          Length = 237

 Score = 55.1 bits (131), Expect = 3e-08
 Identities = 39/116 (33%), Positives = 55/116 (47%), Gaps = 27/116 (23%)

Query: 34  RYSKKSSEDGSPTPGKRGKKGS------PSAQSFEE--------------------LQSQ 67
           R  + +S  G P P +RG          P AQ  E+                     +S+
Sbjct: 34  RLQQAASASGPPAPARRGAPNISRASEVPGAQDDEQERRRRRGRTRVRSEALLHSLRRSR 93

Query: 68  RILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 122
           R+ AN RER R  +LN A  ALR ++P+ P D KL+KI+TL+ A  YI  L + L+
Sbjct: 94  RVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLR 149


>gi|226498192 atonal homolog 8 [Homo sapiens]
          Length = 321

 Score = 54.3 bits (129), Expect = 4e-08
 Identities = 32/86 (37%), Positives = 51/86 (59%), Gaps = 2/86 (2%)

Query: 41  EDGSPTPGKRGKKGSPSAQSFEELQ-SQRILANVRERQRTQSLNEAFAALRKIIPTLP-S 98
           +D S +P KR  + + ++   + LQ ++R+LAN RER R  +++ AF ALRK +P     
Sbjct: 204 QDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYG 263

Query: 99  DKLSKIQTLKLAARYIDFLYQVLQSD 124
            KLSK+  L++A  YI  L ++   D
Sbjct: 264 QKLSKLAILRIACNYILSLARLADLD 289


>gi|161484632 nescient helix loop helix 2 [Homo sapiens]
          Length = 135

 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 29/49 (59%), Positives = 36/49 (73%), Gaps = 1/49 (2%)

Query: 74  RERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVL 121
           RER R ++ N AFA LRK++PTLP D KLSKI+ L+LA  YI +L  VL
Sbjct: 85  RERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 133


>gi|5031945 nescient helix loop helix 2 [Homo sapiens]
          Length = 135

 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 29/49 (59%), Positives = 36/49 (73%), Gaps = 1/49 (2%)

Query: 74  RERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVL 121
           RER R ++ N AFA LRK++PTLP D KLSKI+ L+LA  YI +L  VL
Sbjct: 85  RERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 133


>gi|21553337 atonal homolog 7 [Homo sapiens]
          Length = 152

 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 30/69 (43%), Positives = 41/69 (59%), Gaps = 1/69 (1%)

Query: 58  AQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDF 116
           A   E    +R+ AN RER+R Q LN AF  LR+++P    D KLSK +TL++A  YI  
Sbjct: 32  AGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMA 91

Query: 117 LYQVLQSDE 125
           L ++L   E
Sbjct: 92  LTRILAEAE 100


>gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]
          Length = 271

 Score = 51.2 bits (121), Expect = 4e-07
 Identities = 45/128 (35%), Positives = 55/128 (42%), Gaps = 13/128 (10%)

Query: 5   SSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEEL 64
           SSS  S   S  +S       PK     R   +  +E   P PG     G  +    +E 
Sbjct: 45  SSSSTSSTSSTSSSSTTAPLLPKA---AREKPEAPAEPPGPGPGSGAHPGGSARPDAKEE 101

Query: 65  QSQRI--LANVRERQRTQSLNEAFAALRKII--------PTLPSDKLSKIQTLKLAARYI 114
           Q Q++    N RER+R Q LN A  ALR++I           P  KLSKI TL LA  YI
Sbjct: 102 QQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYI 161

Query: 115 DFLYQVLQ 122
             L   LQ
Sbjct: 162 LLLGSSLQ 169


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.125    0.345 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,253,949
Number of Sequences: 37866
Number of extensions: 277642
Number of successful extensions: 1680
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 125
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 1452
Number of HSP's gapped (non-prelim): 250
length of query: 160
length of database: 18,247,518
effective HSP length: 94
effective length of query: 66
effective length of database: 14,688,114
effective search space: 969415524
effective search space used: 969415524
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.